Detailed information for compound 229565

Basic information

Technical information
  • TDR Targets ID: 229565
  • Name: N-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydro xymethyl)oxan-2-yl]benzamide
  • MW: 283.277 | Formula: C13H17NO6
  • H donors: 5 H acceptors: 5 LogP: -0.93 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]1O[C@@H](NC(=O)c2ccccc2)[C@@H]([C@H]([C@@H]1O)O)O
  • InChi: 1S/C13H17NO6/c15-6-8-9(16)10(17)11(18)13(20-8)14-12(19)7-4-2-1-3-5-7/h1-5,8-11,13,15-18H,6H2,(H,14,19)/t8-,9-,10+,11-,13-/m1/s1
  • InChiKey: SPYSOSUFGSNSMY-BZNQNGANSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]benzamide
  • N-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]benzamide
  • N-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]benzamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus E3 ubiquitin protein ligase LRSAM1 0.0023 0.0072 0.0072
Echinococcus multilocularis sex peptide receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0445 0.3486 0.3484
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0051 0.0297 0.0297
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0052 0.0052
Brugia malayi Cyclic-nucleotide gated cation channel 0.0037 0.019 0.019
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0017 0.0029 0.0029
Echinococcus granulosus E3 ubiquitin protein ligase mib1 0.0023 0.0073 0.0073
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0052 0.0052
Trypanosoma cruzi hypothetical protein, conserved 0.0445 0.3486 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0051 0.0297 0.0297
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0275 0.0275
Schistosoma mansoni peter pan-related 0.0023 0.0072 0.0072
Echinococcus granulosus ring finger protein 113a 0.0023 0.0072 0.0072
Echinococcus multilocularis expressed conserved protein 0.0025 0.009 0.009
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0445 0.3486 0.3486
Treponema pallidum cyclic nucleotide binding protein 0.0025 0.009 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Schistosoma mansoni flap endonuclease-1 0.0027 0.0104 0.0104
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0119 0.0341
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.009 0.009
Echinococcus granulosus netrin receptor unc 5 0.0016 0.002 0.002
Treponema pallidum catabolite gene activator 0.0025 0.009 1
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0014 0.0004 0.0001
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0052 0.0052
Echinococcus granulosus ring finger protein 170 0.0023 0.0072 0.0072
Schistosoma mansoni netrin receptor unc5 0.0016 0.002 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0052 0.0049
Echinococcus multilocularis aryl hydrocarbon receptor 0.0014 0.0004 0.0004
Schistosoma mansoni ATPase 0.0017 0.0028 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Leishmania major hypothetical protein, conserved 0.0023 0.0072 0.0206
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0051 0.0297 0.0297
Brugia malayi hypothetical protein 0.0018 0.0037 0.0037
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0052 0.0052
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.0297 0.0297
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0023 0.0073 0.0073
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0052 0.0052
Brugia malayi B-box zinc finger family protein 0.0023 0.0072 0.0072
Echinococcus multilocularis geminin 0.0192 0.1436 0.1436
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0025 0.009 0.009
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0194 0.1454 0.1454
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0033 0.0033
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0023 0.0072 0.0072
Loa Loa (eye worm) MH2 domain-containing protein 0.0135 0.0979 0.0976
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0052 0.0048
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0297 0.0297
Onchocerca volvulus 0.0025 0.009 0.0086
Echinococcus multilocularis zinc finger protein Ran binding 0.0445 0.3486 0.3486
Entamoeba histolytica zinc finger domain containing protein 0.0023 0.0072 0.058
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0119 0.0119
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.1252 1 1
Echinococcus multilocularis hyperpolarization activated cyclic 0.0037 0.019 0.019
Echinococcus granulosus tachykinin peptides receptor 99D 0.0051 0.0297 0.0297
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0033 0.0033
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0189 0.1413 0.1413
Giardia lamblia Hypothetical protein 0.0023 0.0072 0.3596
Leishmania major hypothetical protein, conserved 0.0023 0.0072 0.0206
Echinococcus multilocularis expressed conserved protein 0.0105 0.0733 0.0733
Schistosoma mansoni amine GPCR 0.0051 0.0297 0.0297
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0052 0.0052
Schistosoma mansoni ring finger protein 151 0.0023 0.0072 0.0072
Leishmania major protein kinase, putative 0.0039 0.0206 0.059
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0025 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0017 0.0028 0.0025
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0445 0.3486 1
Trichomonas vaginalis flap endonuclease-1, putative 0.0029 0.0127 0.0127
Brugia malayi sulfakinin receptor protein 0.0051 0.0297 0.0297
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0052 0.0048
Onchocerca volvulus 0.0268 0.2053 0.205
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0025 0.009 0.009
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0019 0.0019
Leishmania major hypothetical protein, conserved 0.0023 0.0072 0.0206
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0176 0.1313 0.1313
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Giardia lamblia Kinase, NEK 0.0023 0.0072 0.3596
Onchocerca volvulus Matrilysin homolog 0.0022 0.0066 0.0062
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0029 0.0127 0.0363
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.0297 0.0297
Toxoplasma gondii helicase, putative 0.0023 0.0072 0.0072
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0024 0.0082 0.0235
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0297 0.0297
Echinococcus granulosus nervana 2 0.0315 0.2435 0.2435
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0017 0.0029 0.0029
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0025 0.009 0.009
Onchocerca volvulus 0.0051 0.0297 0.0293
Onchocerca volvulus 0.0051 0.0297 0.0293
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0052 0.0052
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0.0028 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0297 0.0297
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0033 0.0033
Echinococcus granulosus neuropeptide receptor 0.0051 0.0297 0.0297
Onchocerca volvulus 0.0042 0.0228 0.0223
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Toxoplasma gondii SWI2/SNF2-containing protein RAD5 0.0023 0.0072 0.0072
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0037 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0024 0.0082 0.0713
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0052 0.0052
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0051 0.0297 0.0297
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0021 0.0021
Schistosoma mansoni alpha-1 adrenergic receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Plasmodium vivax E3 ubiquitin-protein ligase, putative 0.0023 0.0072 0.0051
Trichomonas vaginalis cell cycle control protein cwf24, putative 0.0023 0.0072 0.0072
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0017 0.0028 0.008
Loa Loa (eye worm) hypothetical protein 0.0056 0.0344 0.0341
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0315 0.2435 0.2435
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0052 0.0049
Brugia malayi Death domain containing protein 0.0016 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0031 0.0139 0.0136
Brugia malayi G-protein coupled receptor 0.0051 0.0297 0.0297
Echinococcus granulosus GPCR family 2 0.0018 0.0033 0.0033
Echinococcus multilocularis musashi 0.003 0.0135 0.0135
Echinococcus granulosus ring and YY1 binding protein 0.0445 0.3486 0.3486
Echinococcus multilocularis protein dispatched 1 0.0055 0.0329 0.0329
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0036 0.0183 1
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0445 0.3486 0.3486
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Echinococcus granulosus FTZ F1 alpha 0.002 0.0052 0.0052
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0004 0.0004
Brugia malayi CHE-14 protein 0.0048 0.0275 0.0275
Echinococcus granulosus 7tm_1 domain containing protein 0.0051 0.0297 0.0297
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0072 0.0206
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0082 0.0235
Brugia malayi hypoxia-induced factor 1 0.017 0.1264 0.1264
Giardia lamblia Ribonuclease 0.0023 0.0072 0.3596
Leishmania major hypothetical protein, conserved 0.0023 0.0072 0.0206
Brugia malayi Serotonin receptor 0.0051 0.0297 0.0297
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0042 0.0228 0.0228
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0445 0.3486 0.3486
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0014 0.0004 0.0012
Brugia malayi G protein-coupled receptor 0.0051 0.0297 0.0297
Plasmodium falciparum E3 ubiquitin-protein ligase RNF5, putative 0.0023 0.0072 0.0072
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0084 0.0084
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.019 0.019
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0039 0.02 0.02
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0445 0.3486 0.3486
Echinococcus granulosus dro:myosuppressin receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0051 0.0297 0.0297
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0052 0.0049
Brugia malayi Calcitonin receptor-like protein seb-1 0.0056 0.0344 0.0344
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0039 0.02 0.02
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Echinococcus multilocularis sodium:potassium transporting ATPase subunit 0.0315 0.2435 0.2435
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0025 0.009 0.009
Trypanosoma brucei protein kinase A regulatory subunit 0.0025 0.009 0.0259
Leishmania major hypothetical protein, conserved 0.0023 0.0072 0.0206
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0049
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0051 0.0297 0.0297
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0052 0.0052
Mycobacterium tuberculosis Conserved hypothetical protein 0.0025 0.009 0.7929
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Brugia malayi Pre-SET motif family protein 0.0034 0.0161 0.0161
Schistosoma mansoni hypothetical protein 0.0023 0.0072 0.0072
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0052 0.0052
Trichomonas vaginalis adenylate cyclase, putative 0.0017 0.0029 0.0029
Loa Loa (eye worm) hypoxia-induced factor 1 0.017 0.1264 0.1261
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0297 0.0297
Schistosoma mansoni inhibitor of apoptosis 1 diap1 0.0023 0.0072 0.0072
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.002 0.002
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0033 0.003
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0049
Echinococcus multilocularis survival motor neuron protein 1 0.0267 0.2048 0.2048
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0151 0.0151
Onchocerca volvulus 0.003 0.0135 0.0131
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.008 0.0534 0.0534
Onchocerca volvulus 0.0023 0.0072 0.0068
Plasmodium falciparum flap endonuclease 1 0.0029 0.0127 0.0127
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Loa Loa (eye worm) flap endonuclease-1 0.0029 0.0127 0.0124
Onchocerca volvulus 0.0051 0.0297 0.0293
Brugia malayi Ets-domain containing protein 0.0082 0.055 0.055
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0082 0.0082
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0072 0.0206
Schistosoma mansoni biogenic amine receptor 0.0051 0.0297 0.0297
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.009 0.009
Giardia lamblia Hypothetical protein 0.0023 0.0072 0.3596
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0033 0.0033
Trichomonas vaginalis adenylate cyclase, putative 0.0017 0.0029 0.0029
Echinococcus multilocularis neuropeptide FF receptor 2 0.0051 0.0297 0.0297
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0025 0.009 0.009
Echinococcus multilocularis nervana 2 0.0315 0.2435 0.2435
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0033 0.0033
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0037 0.019 0.0187
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0033 0.0013
Loa Loa (eye worm) hypothetical protein 0.003 0.0131 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0025 0.009 0.009
Mycobacterium leprae Possible transporter protein 0.0017 0.0029 0.1374
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Onchocerca volvulus 0.0051 0.0297 0.0293
Trypanosoma brucei Aph-1 protein, putative 0.0093 0.0641 0.1839
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0069
Giardia lamblia Flap structure-specific endonuclease 0.0029 0.0127 0.6339
Loa Loa (eye worm) hypothetical protein 0.0055 0.033 0.0327
Entamoeba histolytica zinc finger domain containing protein 0.0023 0.0072 0.058
Plasmodium vivax hypothetical protein, conserved 0.1252 1 1
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0025 0.009 0.009
Onchocerca volvulus 0.0051 0.0297 0.0293
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0039 0.02 1
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0023 0.0072 0.0072
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0025 0.009 0.009
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0017 0.0028 0.0028
Echinococcus granulosus g-protein coupled receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0025 0.009 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0029 0.0029
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0017 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0055 0.033 0.033
Mycobacterium ulcerans hypothetical protein 0.0025 0.009 0.3122
Schistosoma mansoni rnf5 0.0023 0.0072 0.0072
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0055 0.033 0.033
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0082 0.0082
Loa Loa (eye worm) matrixin family protein 0.0053 0.0318 0.0315
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0029 0.0029
Treponema pallidum cyclic nucleotide binding protein 0.0025 0.009 1
Onchocerca volvulus 0.0315 0.2435 0.2432
Echinococcus granulosus g protein coupled receptor 0.0051 0.0297 0.0297
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0069
Onchocerca volvulus Protein neuralized homolog 0.0023 0.0072 0.0068
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0052 0.0052
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Echinococcus multilocularis voltage gated potassium channel 0.0055 0.033 0.033
Onchocerca volvulus 0.0445 0.3486 0.3483
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0052 0.0052
Entamoeba histolytica zinc finger domain containing protein 0.0023 0.0072 0.058
Brugia malayi Hemopexin family protein 0.0031 0.014 0.014
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0049
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0025 0.009 0.0087
Brugia malayi Melatonin receptor type 1A 0.0051 0.0297 0.0297
Schistosoma mansoni hypothetical protein 0.0031 0.014 0.014
Giardia lamblia Protein 21.1 0.0023 0.0073 0.3652
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0083 0.0561 0.0561
Schistosoma mansoni myosin xvIII 0.0051 0.0297 0.0297
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Brugia malayi hypothetical protein 0.0138 0.1 0.1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0052 0.0052
Echinococcus multilocularis sterol regulatory element binding protein 0.0048 0.0275 0.0275
Echinococcus multilocularis lamin 0.003 0.0135 0.0135
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0023 0.0072 0.0072
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0027 0.0105 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0051 0.0297 0.0297
Echinococcus multilocularis serotonin receptor 0.0051 0.0297 0.0297
Echinococcus granulosus somatostatin receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0022 0.0066 0.0063
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0017 0.0028 0.008
Onchocerca volvulus 0.003 0.0135 0.0131
Echinococcus multilocularis ring finger protein 170 0.0023 0.0072 0.0072
Echinococcus multilocularis neuropeptide receptor A26 0.0051 0.0297 0.0297
Echinococcus granulosus Ankyrin 0.0016 0.0021 0.0021
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0052 0.0052
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0024 0.0082 0.0082
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0025 0.009 0.009
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0051 0.0297 0.0297
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0025 0.009 0.451
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0069
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0082 0.0082
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0025 0.009 0.7929
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0033 0.0095
Schistosoma mansoni thyroid hormone receptor 0.002 0.0052 0.0052
Onchocerca volvulus 0.0445 0.3486 0.3483
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.002 0.002
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0033 0.0033
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0297 0.0297
Entamoeba histolytica hypothetical protein 0.0041 0.0217 0.2495
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0014 0.0004 0.0012
Toxoplasma gondii hypothetical protein 0.0023 0.0072 0.0072
Brugia malayi hypothetical protein 0.0051 0.0297 0.0297
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Brugia malayi Matrixin family protein 0.0022 0.0066 0.0066
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0297 0.0297
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0556 0.4376 0.4376
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0025 0.009 0.0086
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0052 0.0052
Schistosoma mansoni amine GPCR 0.0051 0.0297 0.0297
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0052 0.0049
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0069
Giardia lamblia Hypothetical protein 0.0023 0.0072 0.3596
Schistosoma mansoni hypothetical protein 0.0051 0.0297 0.0297
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Giardia lamblia Zinc finger domain 0.0023 0.0072 0.3596
Trypanosoma cruzi cAMP response protein 1 0.0025 0.009 0.0259
Echinococcus multilocularis RING finger and transmembrane domain containing protein 0.0023 0.0072 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0297 0.0297
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0025 0.009 0.009
Brugia malayi Hypothetical RING finger protein C16C10.7 in chromosome III 0.0023 0.0072 0.0072
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0051 0.0297 0.0297
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0017 0.0028 0.0028
Echinococcus granulosus GA binding protein alpha chain 0.0082 0.055 0.055
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0082 0.055 0.0547
Loa Loa (eye worm) hypothetical protein 0.0315 0.2435 0.2433
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0135 0.0135
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0161 0.0161
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Echinococcus granulosus Zinc finger RanBP2 type 0.0445 0.3486 0.3486
Giardia lamblia Zinc finger domain 0.0023 0.0072 0.3596
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.02 0.02
Schistosoma mansoni hypothetical protein 0.0046 0.0261 0.0261
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0052 0.0052
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0025 0.009 0.009
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0025 0.009 0.009
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0072 0.0206
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.0046 0.0261 0.0261
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0297 0.0297
Schistosoma mansoni hypothetical protein 0.0192 0.1436 0.1436
Loa Loa (eye worm) hypothetical protein 0.0022 0.0066 0.0063
Onchocerca volvulus 0.0023 0.0072 0.0068
Schistosoma mansoni coup transcription factor 0.002 0.0052 0.0052
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0014 0.0004 0.0004
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0019 0.0044 0.0041
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0024 0.0082 0.0082
Trypanosoma brucei hypothetical protein, conserved 0.0445 0.3486 1
Schistosoma mansoni voltage-gated potassium channel 0.0206 0.1553 0.1553
Plasmodium falciparum trophozoite exported protein 1 0.0023 0.0072 0.0072
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0017 0.0029 0.0029
Onchocerca volvulus 0.0051 0.0297 0.0293
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Echinococcus granulosus alpha 1A adrenergic receptor 0.0051 0.0297 0.0297
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0004
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.0297 0.0297
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0072 0.0206
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0119 0.0099
Loa Loa (eye worm) pax transcription factor protein 2 0.0272 0.2087 0.2084
Mycobacterium ulcerans transmembrane transport protein 0.0025 0.009 0.3122
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0051 0.0297 0.0297
Giardia lamblia Hypothetical protein 0.0023 0.0072 0.3596
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Brugia malayi N-terminal motif family protein 0.0025 0.009 0.009
Giardia lamblia Kinase, NEK 0.0023 0.0072 0.3596
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Echinococcus multilocularis Ankyrin 0.0016 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0445 0.3486 0.3484
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0161 0.0161
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0025 0.009 0.009
Leishmania major DNA repair protein-like protein 0.0023 0.0072 0.0206
Schistosoma mansoni patched 1 0.0048 0.0275 0.0275
Onchocerca volvulus 0.0194 0.1454 0.145
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0051 0.0297 0.0294
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0048 0.0275 0.0272
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0297 0.0297
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.0297 0.0297
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0297 0.0297
Toxoplasma gondii RING zinc finger protein 0.0023 0.0072 0.0072
Echinococcus granulosus neuropeptide receptor A26 0.0051 0.0297 0.0297
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0297 0.0297
Mycobacterium ulcerans hydrolase 0.0027 0.0105 0.3867
Schistosoma mansoni neuropeptide receptor 0.0051 0.0297 0.0297
Brugia malayi GnHR receptor homolog 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.002 0.002
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0025 0.009 0.009
Loa Loa (eye worm) matrixin family protein 0.0049 0.0282 0.0279
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0297 0.0297
Trichomonas vaginalis ankyrin, putative 0.0023 0.0073 0.0073
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0051 0.0297 0.0297
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0025 0.009 0.0259
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0052 0.0049
Plasmodium vivax RING zinc finger protein, putative 0.0023 0.0072 0.0051
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0189 0.1413 0.141
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0052 0.0052
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0024 0.0082 0.0078
Brugia malayi hypothetical protein 0.0051 0.0297 0.0297
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0025 0.009 0.007
Trichomonas vaginalis adenylate cyclase type III, putative 0.0017 0.0029 0.0029
Echinococcus multilocularis dro:myosuppressin receptor 0.0051 0.0297 0.0297
Echinococcus granulosus cell growth regulator with ring finger domain 0.0023 0.0072 0.0072
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.0297 0.0297
Leishmania major hypothetical protein, unknown function 0.0023 0.0072 0.0206
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0049
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0004 0.0004
Echinococcus multilocularis ring finger protein 113a 0.0023 0.0072 0.0072
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0052 0.0052
Brugia malayi nuclear hormone receptor 0.002 0.0052 0.0052
Echinococcus granulosus nervana 2 0.0315 0.2435 0.2435
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0004 0.0012
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0329 0.0329
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0051 0.0297 0.0294
Plasmodium falciparum cGMP-dependent protein kinase 0.0025 0.009 0.009
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0017 0.0029 0.0029
Echinococcus multilocularis E3 ubiquitin protein ligase LRSAM1 0.0023 0.0072 0.0072
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0051 0.0297 0.0294
Schistosoma mansoni hypothetical protein 0.0039 0.02 0.02
Trichomonas vaginalis adenylate cyclase, putative 0.0017 0.0029 0.0029
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0023 0.0072 0.0206
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0052 0.0052
Brugia malayi isocitrate dehydrogenase 0.0018 0.0033 0.0033
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0084 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Trichomonas vaginalis adenylyl cyclase type V, putative 0.0017 0.0029 0.0029
Echinococcus multilocularis Niemann Pick C1 protein 0.0159 0.1174 0.1174
Echinococcus multilocularis GA binding protein alpha chain 0.0082 0.055 0.055
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0052 0.0052
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0022 0.0066 0.0063
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.0297 0.0297
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0037 0.019 0.019
Leishmania major hypothetical protein, conserved 0.0445 0.3486 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0051 0.0297 0.0297
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0315 0.2435 0.2435
Brugia malayi Dopamine receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0471 0.3692 0.369
Brugia malayi hypothetical protein 0.0051 0.0297 0.0297
Schistosoma mansoni hypothetical protein 0.0018 0.0033 0.0033
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0217 0.0217
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Trichomonas vaginalis hypothetical protein 0.0023 0.0072 0.0072
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0033 0.0033
Echinococcus multilocularis neuropeptide receptor 0.0051 0.0297 0.0297
Plasmodium vivax DNA repair protein RAD5, putative 0.0023 0.0072 0.0051
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0037 0.019 0.019
Brugia malayi hypothetical protein 0.0051 0.0297 0.0297
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0025 0.009 0.009
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0315 0.2435 0.2435
Schistosoma mansoni neuropeptide receptor 0.0051 0.0297 0.0297
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0297 0.0297
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Schistosoma mansoni voltage-gated potassium channel 0.0055 0.033 0.033
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0235 0.1789 0.1787
Echinococcus granulosus Niemann Pick C1 protein 0.0111 0.0788 0.0788
Schistosoma mansoni opsin-like receptor 0.0051 0.0297 0.0297
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Schistosoma mansoni biogenic amine receptor 0.0051 0.0297 0.0297
Giardia lamblia E3 ubiquitin ligase for Rad6p required for the ubiquitination of histone H2B 0.0023 0.0072 0.3596
Echinococcus granulosus lamin dm0 0.003 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.003
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0051 0.0297 0.0297
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0029 0.0029
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.019 0.019
Trichomonas vaginalis adenylate cyclase type, putative 0.0017 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.0046 0.0261 0.0261
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.0297 0.0297
Leishmania major cyclic nucleotide-binding protein-like protein 0.0025 0.009 0.0259
Brugia malayi Serotonin receptor 0.0051 0.0297 0.0297
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0025 0.009 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni RNA binding protein 0.0445 0.3486 0.3486
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0025 0.009 0.0259
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Schistosoma mansoni ATPase 0.0017 0.0028 0.0028
Echinococcus granulosus flap endonuclease 1 0.0029 0.0127 0.0127
Schistosoma mansoni hypothetical protein 0.0025 0.009 0.009
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Chlamydia trachomatis DNA topoisomerase I 0.1252 1 1
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0.0028 0.0028
Onchocerca volvulus 0.0051 0.0297 0.0293
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0033 0.0033
Loa Loa (eye worm) AGC/PKG protein kinase 0.0025 0.009 0.0087
Leishmania major hypothetical protein, conserved 0.0023 0.0072 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0297 0.0297
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0297 0.0297
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0052 0.0052
Brugia malayi Uncoordinated protein 44 0.0016 0.002 0.002
Plasmodium falciparum eukaryotic initiation factor 4A 0.0024 0.0082 0.0082
Schistosoma mansoni hypothetical protein 0.0018 0.0033 0.0033
Entamoeba histolytica hypothetical protein 0.0041 0.0217 0.2495
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0017 0.0029 0.0029
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Brugia malayi PAS domain containing protein 0.0055 0.0333 0.0333
Echinococcus multilocularis nervana 2 0.0194 0.1454 0.1454
Loa Loa (eye worm) hypothetical protein 0.0059 0.0361 0.0358
Trypanosoma brucei hypothetical protein, conserved 0.0445 0.3486 1
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Plasmodium vivax P-type ATPase4, putative 0.0017 0.0028 0.0007
Echinococcus granulosus Protein patched homolog 1 0.0048 0.0275 0.0275
Brugia malayi Matrixin family protein 0.0022 0.0066 0.0066
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0051 0.0297 0.0297
Leishmania major calcium-translocating P-type ATPase 0.0017 0.0028 0.008
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0024 0.0082 0.0082
Brugia malayi hypothetical protein 0.0267 0.2048 0.2048
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0297 0.0297
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.0016 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.0297 0.0297
Brugia malayi MH2 domain containing protein 0.0135 0.0979 0.0979
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Brugia malayi eukaryotic initiation factor 4A 0.0024 0.0082 0.0082
Trypanosoma cruzi cAMP binding protein, putative 0.0025 0.009 0.0259
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0445 0.3486 1
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0023 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0017 0.0028 0.1388
Echinococcus granulosus E3 ubiquitin protein ligase MYLIP 0.0023 0.0072 0.0072
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0017 0.0028 0.0028
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0119 0.0341
Echinococcus granulosus zinc finger protein Ran binding 0.0445 0.3486 0.3486
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.0297 0.0297
Giardia lamblia Hypothetical protein 0.0023 0.0072 0.3596
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0161 0.0161
Echinococcus granulosus RING finger and transmembrane domain containing protein 0.0023 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0005
Echinococcus multilocularis Niemann Pick C1 protein 0.0111 0.0788 0.0788
Echinococcus granulosus gamma secretase subunit aph 1 0.0239 0.1819 0.1819
Schistosoma mansoni amine GPCR 0.0051 0.0297 0.0297
Entamoeba histolytica hypothetical protein 0.0041 0.0217 0.2495
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0025 0.009 0.009
Onchocerca volvulus 0.0051 0.0297 0.0293
Brugia malayi Matrixin family protein 0.0022 0.0066 0.0066
Echinococcus granulosus E3 ubiquitin protein ligase RNF146 0.0023 0.0072 0.0072
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0297 0.0297
Schistosoma mansoni aryl hydrocarbon receptor 0.0055 0.0333 0.0333
Brugia malayi Dopamine receptor protein 2 0.0051 0.0297 0.0297
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.009 0.0259
Schistosoma mansoni single-minded 0.0055 0.0333 0.0333
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0069
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0051 0.0297 0.0297
Echinococcus granulosus tumor protein p63 0.0382 0.2975 0.2975
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0445 0.3486 0.3486
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0025 0.009 0.007
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0025 0.009 0.0259
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0017 0.0029 0.0029
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Echinococcus granulosus hyperpolarization activated cyclic 0.0037 0.019 0.019
Entamoeba histolytica zinc finger domain containing protein 0.0023 0.0072 0.058
Onchocerca volvulus Putative RING finger protein 207 0.0023 0.0072 0.0068
Loa Loa (eye worm) hypothetical protein 0.0034 0.0161 0.0158
Brugia malayi hypothetical protein 0.0023 0.0072 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0297 0.0297
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0017 0.0028 0.008
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Echinococcus multilocularis SWI:SNF matrix associated 0.1252 1 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0049
Onchocerca volvulus 0.0051 0.0297 0.0293
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0025 0.009 0.009
Leishmania major regulatory subunit of protein kinase a-like protein 0.0025 0.009 0.0259
Leishmania major hypothetical protein, conserved 0.0445 0.3486 1
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0004 0.0012
Leishmania major hypothetical protein, conserved 0.0445 0.3486 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0016 0.0021 0.0018
Brugia malayi Ets-domain containing protein 0.0082 0.055 0.055
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0052 0.0052
Echinococcus multilocularis ring and YY1 binding protein 0.0445 0.3486 0.3486
Plasmodium falciparum RING zinc finger protein, putative 0.0023 0.0072 0.0072
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0029 0.0127 0.0363
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Echinococcus granulosus Upstream activation factor subunit UAF30 0.1252 1 1
Brugia malayi AKH receptor 0.0051 0.0297 0.0297
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0052 0.0052
Mycobacterium ulcerans hypothetical protein 0.0025 0.009 0.3122
Echinococcus granulosus hypothetical protein 0.0051 0.0297 0.0297
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0025 0.009 0.009
Echinococcus multilocularis SWI:SNF matrix associated 0.1252 1 1
Echinococcus granulosus sodium:potassium transporting ATPase subunit 0.0315 0.2435 0.2435
Plasmodium vivax SET domain protein, putative 0.0034 0.0161 0.0141
Leishmania major hypothetical protein, conserved 0.0023 0.0072 0.0206
Brugia malayi Fli-1 protein 0.0249 0.1897 0.1897
Brugia malayi ORL1-like opioid receptor 0.0051 0.0297 0.0297
Brugia malayi Pre-SET motif family protein 0.0235 0.1789 0.1789
Schistosoma mansoni hypothetical protein 0.0051 0.0297 0.0297
Echinococcus granulosus nervana 2 0.0194 0.1454 0.1454
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Leishmania major protein kinase, putative 0.0014 0.0004 0.0012
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Loa Loa (eye worm) hypothetical protein 0.003 0.0135 0.0132
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Schistosoma mansoni adenoreceptor 0.0051 0.0297 0.0297
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.0297 0.0297
Schistosoma mansoni hypothetical protein 0.0017 0.0029 0.0029
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0025 0.009 0.009
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0445 0.3486 1
Schistosoma mansoni voltage-gated potassium channel 0.0206 0.1553 0.1553
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0055 0.0329 0.0329
Brugia malayi Neuralized family protein 0.0023 0.0072 0.0072
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Trichomonas vaginalis set domain proteins, putative 0.0268 0.2052 0.2052
Schistosoma mansoni hypothetical protein 0.0018 0.0033 0.0033
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0051 0.0297 0.0297
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0052 0.0052
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0017 0.0029 0.0029
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0037 0.019 0.019
Brugia malayi hypothetical protein 0.0041 0.0217 0.0217
Echinococcus granulosus cGMP dependent protein kinase 1 0.0025 0.009 0.009
Brugia malayi hypothetical protein 0.0023 0.0072 0.0072
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0052 0.0052
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0017 0.0029 0.0029
Echinococcus granulosus neuropeptide receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0.0028 0.0028
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.0297 0.0297
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0.0028 0.0028
Schistosoma mansoni zinc finger protein 0.0445 0.3486 0.3486
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.1252 1 1
Trichomonas vaginalis adenylate cyclase, putative 0.0017 0.0029 0.0029
Onchocerca volvulus 0.0051 0.0297 0.0293
Schistosoma mansoni sodium / potassium ATPase beta chain 0.0194 0.1454 0.1454
Echinococcus multilocularis 0.0023 0.0072 0.0072
Trichomonas vaginalis adenylate cyclase type VI, putative 0.0017 0.0029 0.0029
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0315 0.2435 0.2435
Brugia malayi YY1-associated factor 2 0.0445 0.3486 0.3486
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Brugia malayi G protein-coupled receptor F59B2.13 0.0051 0.0297 0.0297
Leishmania major hypothetical protein, conserved 0.0025 0.009 0.0259
Loa Loa (eye worm) hypothetical protein 0.0445 0.3486 0.3484
Schistosoma mansoni hypothetical protein 0.0051 0.0297 0.0297
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0025 0.009 0.0259
Echinococcus granulosus Na:K ATPase alpha subunit 0.0039 0.02 0.02
Schistosoma mansoni transmemberane protein 0.0315 0.2435 0.2435
Loa Loa (eye worm) hypothetical protein 0.0029 0.0119 0.0116
Echinococcus granulosus voltage gated potassium channel 0.0055 0.033 0.033
Brugia malayi hypothetical protein 0.0185 0.1379 0.1379
Echinococcus multilocularis RING finger protein 185 0.0023 0.0072 0.0072
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0023 0.0072 0.0072
Onchocerca volvulus 0.1252 1 1
Giardia lamblia Protein 21.1 0.0023 0.0073 0.3652
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.0297 0.0297
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0025 0.009 0.009
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0025 0.009 0.009
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0051 0.0297 0.0294
Echinococcus granulosus aryl hydrocarbon receptor 0.0014 0.0004 0.0004
Trichomonas vaginalis adenylate cyclase, putative 0.0017 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0029 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.009 0.009
Echinococcus multilocularis SWI:SNF matrix associated 0.1252 1 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0017 0.0029 0.0029
Schistosoma mansoni lamin 0.003 0.0135 0.0135
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0052 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0029 0.0029
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0217 0.0217
Echinococcus granulosus neuropeptide FF receptor 2 0.0051 0.0297 0.0297
Schistosoma mansoni amine GPCR 0.0051 0.0297 0.0297
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0025 0.009 0.0086
Trypanosoma cruzi protein kinase A regulatory subunit 0.0025 0.009 0.0259
Echinococcus granulosus lamin 0.003 0.0135 0.0135
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0025 0.009 0.7929
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0033 0.0033
Schistosoma mansoni brg-1 associated factor 0.1252 1 1
Echinococcus granulosus expressed conserved protein 0.0105 0.0733 0.0733
Entamoeba histolytica zinc finger domain containing protein 0.0023 0.0072 0.058
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0025 0.0089 0.0085
Loa Loa (eye worm) hypothetical protein 0.0185 0.1379 0.1377
Leishmania major eukaryotic initiation factor 4a, putative 0.0024 0.0082 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Trichomonas vaginalis adenylate cyclase, putative 0.0017 0.0029 0.0029
Brugia malayi RING zinc finger protein 0.0023 0.0072 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Echinococcus granulosus cGMP dependent protein kinase 0.0025 0.009 0.009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0161 0.0161
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0037 0.019 0.019
Schistosoma mansoni hypothetical protein 0.0023 0.0072 0.0072
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0297 0.0297
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0033 0.0095
Schistosoma mansoni gamma-secretase subunit aph-1 0.0239 0.1819 0.1819
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0037 0.019 0.019
Leishmania major hypothetical protein, conserved 0.0023 0.0072 0.0206
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.0051 0.0297 0.0297
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0025 0.009 0.009
Treponema pallidum catabolite gene activator (Crp) 0.0025 0.009 1
Onchocerca volvulus 0.0051 0.0297 0.0293
Loa Loa (eye worm) hypothetical protein 0.0267 0.2048 0.2046
Echinococcus multilocularis E3 ubiquitin protein ligase Bre1 0.0023 0.0072 0.0072
Giardia lamblia Protein 21.1 0.0023 0.0073 0.3652
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0297 0.0297
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0052 0.0048
Brugia malayi hypothetical protein 0.0051 0.0297 0.0297
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0052 0.0052
Leishmania major hypothetical protein, conserved 0.0025 0.009 0.0259
Echinococcus granulosus patatin phospholipase domain containing protein 0.0025 0.009 0.009
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.002 0.002
Brugia malayi neuropeptide F receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Schistosoma mansoni voltage-gated potassium channel 0.0055 0.033 0.033
Echinococcus multilocularis transfer RNA-Lys 0.0041 0.0218 0.0218
Toxoplasma gondii P-type ATPase4, putative 0.0017 0.0028 0.0028
Toxoplasma gondii hypothetical protein 0.0023 0.0072 0.0072
Trypanosoma brucei DNA repair protein, putative 0.0023 0.0072 0.0206
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0297 0.0297
Trichomonas vaginalis hypothetical protein 0.0017 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Onchocerca volvulus 0.0051 0.0297 0.0293
Brugia malayi hypothetical protein 0.0023 0.0072 0.0072
Leishmania major hypothetical protein 0.0023 0.0072 0.0206
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0084 0.0084
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0315 0.2435 0.2435
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0017 0.0029 0.0029
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0023 0.0072 0.0072
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Leishmania major protein kinase, putative 0.0025 0.009 0.0259
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.1252 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Trichomonas vaginalis intestinal guanylate cyclase, putative 0.0017 0.0029 0.0029
Entamoeba histolytica zinc finger domain containing protein 0.0023 0.0072 0.058
Echinococcus multilocularis protein patched 0.0048 0.0275 0.0275
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0033 0.0033
Echinococcus granulosus survival motor neuron protein 1 0.0267 0.2048 0.2048
Echinococcus granulosus E3 ubiquitin protein ligase Bre1 0.0023 0.0072 0.0072
Brugia malayi G-protein coupled receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.0297 0.0294
Echinococcus granulosus geminin 0.0192 0.1436 0.1436
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0161 0.0161
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0025 0.009 0.009
Loa Loa (eye worm) RecQ helicase 0.0024 0.0084 0.0081
Brugia malayi neuropeptide F receptor 0.0051 0.0297 0.0297
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0445 0.3486 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.0297 0.0297
Echinococcus granulosus serotonin receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0048 0.0275 0.0272
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.0087
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.0297 0.0294
Schistosoma mansoni ets-related 0.0249 0.1897 0.1897
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0051 0.0297 0.0297
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0194 0.1454 0.1454
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.009 0.009
Mycobacterium tuberculosis Conserved hypothetical protein 0.0025 0.009 0.7929
Brugia malayi RE15519p 0.0051 0.0297 0.0297
Schistosoma mansoni TRABID protein (C64 family) 0.0445 0.3486 0.3486
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Plasmodium falciparum zinc finger protein, putative 0.0023 0.0072 0.0072
Chlamydia trachomatis SWIB complex protein 0.1252 1 1
Brugia malayi brahma associated protein 60 kDa 0.1252 1 1
Toxoplasma gondii hypothetical protein 0.0023 0.0072 0.0072
Echinococcus multilocularis G protein coupled receptor 139 0.0051 0.0297 0.0297
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0025 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Brugia malayi hypothetical protein 0.0051 0.0297 0.0297
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0052 0.0052
Leishmania major hypothetical protein, conserved 0.0029 0.0119 0.0341
Trichomonas vaginalis adenylate cyclase, putative 0.0017 0.0029 0.0029
Brugia malayi Dopamine receptor protein 1 0.0051 0.0297 0.0297
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.1252 1 1
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0025 0.009 0.009
Loa Loa (eye worm) TYRA-2 protein 0.0051 0.0297 0.0294
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0052 0.0052
Onchocerca volvulus 0.0051 0.0297 0.0293
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.0297 0.0297
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0135 0.0132
Onchocerca volvulus 0.0023 0.0072 0.0068
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0027 0.0105 0.0105
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0445 0.3486 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0052 0.0049
Mycobacterium tuberculosis Conserved protein 0.0025 0.009 0.7929
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0297 0.0297
Loa Loa (eye worm) RING finger protein 20 0.0023 0.0072 0.0069
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0049
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0022 0.0066 0.0066
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0297 0.0297
Leishmania major hypothetical protein, conserved 0.0445 0.3486 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0052 0.0049
Onchocerca volvulus 0.0055 0.0329 0.0325
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0017 0.0029 0.0029
Echinococcus granulosus neuropeptide s receptor 0.0051 0.0297 0.0297
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0017 0.0028 0.008
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0119 0.0341
Echinococcus granulosus sterol regulatory element binding protein 0.0048 0.0275 0.0275
Trichomonas vaginalis ion channel nompc, putative 0.0023 0.0072 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.1252 1 1
Entamoeba histolytica zinc finger domain containing protein 0.0023 0.0072 0.058
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0029 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.007 0.0454 0.0451
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0069
Toxoplasma gondii ran binding protein 0.0445 0.3486 0.3486
Plasmodium vivax trophozoite exported protein 1, putative 0.0023 0.0072 0.0051
Brugia malayi follicle stimulating hormone receptor 0.0051 0.0297 0.0297
Mycobacterium ulcerans hypothetical protein 0.0025 0.009 0.3122
Echinococcus multilocularis E3 ubiquitin protein ligase MYLIP 0.0023 0.0072 0.0072
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0014 0.0004 0.0004
Onchocerca volvulus 0.0031 0.014 0.0136
Echinococcus multilocularis nervana 2 0.0315 0.2435 0.2435
Trypanosoma cruzi hypothetical protein, conserved 0.0445 0.3486 1
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0004
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0004 0.0012
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0033 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Brugia malayi hypothetical protein 0.0023 0.0072 0.0072
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Onchocerca volvulus 0.0445 0.3486 0.3483
Trypanosoma brucei SNF2 family N-terminal domain/Ring finger domain containing protein, putative 0.0023 0.0072 0.0206
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0033 0.003
Plasmodium falciparum E3 ubiquitin-protein ligase, putative 0.0023 0.0072 0.0072
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0082 0.0082
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0017 0.0028 0.0028
Trypanosoma brucei predicted zinc finger protein 0.0023 0.0072 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0029 0.0029
Echinococcus multilocularis G-protein coupled receptor, putative 0.0051 0.0297 0.0297
Schistosoma mansoni cellular tumor antigen P53 0.0056 0.034 0.034
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Onchocerca volvulus 0.0445 0.3486 0.3483
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Trypanosoma cruzi hypothetical protein 0.0023 0.0072 0.0206
Trypanosoma cruzi Aph-1 protein, putative 0.0093 0.0641 0.1839
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni nuclear hormone receptor 0.002 0.0052 0.0052
Echinococcus granulosus peptide allatostatin:somatostatin 0.0051 0.0297 0.0297
Brugia malayi SWIB/MDM2 domain containing protein 0.1252 1 1
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0023 0.0072 0.0206
Leishmania major hypothetical protein, conserved 0.0023 0.0072 0.0206
Schistosoma mansoni thyroid hormone receptor 0.002 0.0052 0.0052
Trypanosoma brucei Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni amine GPCR 0.0051 0.0297 0.0297
Entamoeba histolytica SPRY domain protein 0.0023 0.0072 0.058
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0014 0.0004 0.0004
Echinococcus multilocularis fmrfamide receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0056 0.0344 0.0341
Giardia lamblia Kinase 0.0023 0.0072 0.3596
Brugia malayi Protein kinase domain containing protein 0.0016 0.002 0.002
Onchocerca volvulus 0.002 0.0052 0.0048
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0297 0.0297
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0297 0.0297
Entamoeba histolytica hypothetical protein 0.0041 0.0217 0.2495
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0036 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0025 0.009 0.009
Onchocerca volvulus 0.0051 0.0297 0.0293
Toxoplasma gondii Bardet-Biedl syndrome 5, putative 0.0023 0.0072 0.0072
Onchocerca volvulus 0.0056 0.034 0.0336
Onchocerca volvulus 0.0022 0.0066 0.0062
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0025 0.009 0.009
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0052 0.0052
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0033 0.0095
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0017 0.0028 0.0028
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0017 0.0028 0.0028
Echinococcus multilocularis somatostatin receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) RiNg Finger protein family member 0.0023 0.0072 0.0069
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0052 0.0049
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Toxoplasma gondii hypothetical protein 0.0023 0.0072 0.0072
Echinococcus multilocularis allatostatin A receptor 0.0051 0.0297 0.0297
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0.0028 0.0028
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.0297 0.0297
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0017 0.0029 0.0029
Brugia malayi hypothetical protein 0.0051 0.0297 0.0297
Brugia malayi Pax transcription factor protein 2 0.0272 0.2087 0.2087
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0004 0.0012
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0445 0.3486 1
Echinococcus granulosus single minded 2 0.0058 0.0358 0.0358
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0052 0.0052
Trichomonas vaginalis ankyrin, putative 0.0023 0.0073 0.0073
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0217 0.0217
Trichomonas vaginalis adenylate cyclase type, putative 0.0017 0.0029 0.0029
Brugia malayi putative neuropeptide receptor NPR1 0.0051 0.0297 0.0297
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0017 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0164 0.1212 0.1209
Echinococcus granulosus Niemann Pick C1 protein 0.0159 0.1174 0.1174
Brugia malayi RING finger protein 20 0.0023 0.0072 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni neuropeptide receptor 0.0051 0.0297 0.0297
Brugia malayi nuclear receptor NHR-88 0.002 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.0018 0.0033 0.0033
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0.0028 0.0028
Trypanosoma brucei cAMP binding protein, putative 0.0025 0.009 0.0259
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0023 0.0072 0.0072
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0004 0.0004
Echinococcus granulosus cGMP dependent protein kinase 1 0.0025 0.009 0.009
Onchocerca volvulus Matrilysin homolog 0.0049 0.0282 0.0278
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0017 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0029 0.0029
Leishmania major protein kinase A regulatory subunit, putative 0.0025 0.009 0.0259
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0017 0.0029 0.0029
Echinococcus granulosus nuclear factor of activated T cells 5 0.0083 0.0561 0.0561
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0008 0.0008
Mycobacterium ulcerans putative regulatory protein 0.0041 0.0218 0.9505
Loa Loa (eye worm) melatonin receptor type 1A 0.0051 0.0297 0.0294
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0049
Schistosoma mansoni histamine h1 receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0069
Echinococcus granulosus g protein coupled receptor 0.0051 0.0297 0.0297
Onchocerca volvulus 0.0023 0.0072 0.0068
Entamoeba histolytica hypothetical protein 0.0023 0.0072 0.058
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.0297 0.0294
Trypanosoma brucei ring finger containing protein 0.0023 0.0072 0.0206
Echinococcus multilocularis orexin receptor type 2 0.0051 0.0297 0.0297
Brugia malayi hypothetical protein 0.0051 0.0297 0.0297
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0445 0.3486 1
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0072 0.0206
Leishmania major hypothetical protein, conserved 0.0445 0.3486 1
Trichomonas vaginalis sex-determining protein fem-1, putative 0.0023 0.0072 0.0072
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0056 0.0344 0.0344
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0051 0.0297 0.0297
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0445 0.3486 0.3486
Onchocerca volvulus 0.0051 0.0297 0.0293
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0161 0.0161
Trichomonas vaginalis adenylate cyclase, putative 0.0017 0.0029 0.0029
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0297 0.0297
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0297 0.0297
Brugia malayi hypothetical protein 0.0023 0.0072 0.0072
Echinococcus granulosus fmrfamide receptor 0.0051 0.0297 0.0297
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0051 0.0297 0.0297
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0025 0.009 0.009
Schistosoma mansoni hypothetical protein 0.1252 1 1
Schistosoma mansoni lamin 0.003 0.0135 0.0135
Schistosoma mansoni hypothetical protein 0.0192 0.1436 0.1436
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0025 0.009 0.009
Echinococcus multilocularis flap endonuclease 1 0.0029 0.0127 0.0127
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0014 0.0004 0.0004
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0176 0.1313 0.1313
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0052 0.0052
Brugia malayi Egg laying defective protein 4 0.0025 0.009 0.009
Onchocerca volvulus 0.0051 0.0297 0.0293
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Schistosoma mansoni neuropeptide receptor 0.0051 0.0297 0.0297
Brugia malayi bHLH-PAS transcription factor 0.0041 0.0218 0.0218
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0072 0.0072
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0025 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0359 0.2786 0.2784
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0025 0.009 0.0259
Schistosoma mansoni opsin-like receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0025 0.009 0.7929
Onchocerca volvulus 0.0272 0.2087 0.2083
Trichomonas vaginalis adenylate cyclase type, putative 0.0017 0.0029 0.0029
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0111 0.0788 0.0785
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0297 0.0297
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0082 0.0235
Schistosoma mansoni mind bomb 0.0023 0.0073 0.0073
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0017 0.0028 0.008
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.1252 1 1
Trypanosoma cruzi cAMP response protein 1, putative 0.0025 0.009 0.0259
Loa Loa (eye worm) hypothetical protein 0.0039 0.02 0.0197
Echinococcus multilocularis neuropeptide s receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0297 0.0297
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0445 0.3486 0.3483
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0017 0.0029 0.0029
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0017 0.0028 0.0028
Schistosoma mansoni fusion 0.0445 0.3486 0.3486
Brugia malayi hypothetical protein 0.0023 0.0072 0.0072
Trichomonas vaginalis adenylate cyclase, putative 0.0017 0.0029 0.0029
Schistosoma mansoni opsin-like receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) intermediate filament protein 0.003 0.0135 0.0132
Schistosoma mansoni hypothetical protein 0.0041 0.0217 0.0217
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0051 0.0297 0.0297
Schistosoma mansoni growth hormone secretagogue receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.0087
Entamoeba histolytica hypothetical protein 0.0023 0.0072 0.058
Echinococcus granulosus eukaryotic initiation factor 4A 0.0024 0.0082 0.0082
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0445 0.3486 0.3486
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0051 0.0297 0.0297
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0017 0.0029 0.0029
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0239 0.1819 0.1817
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.002 0.002
Echinococcus granulosus G protein coupled receptor 139 0.0051 0.0297 0.0297
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0445 0.3486 0.3486
Leishmania major hypothetical protein, conserved 0.0023 0.0072 0.0206
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0043 0.0043
Brugia malayi Matrixin family protein 0.0053 0.0318 0.0318
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0037 0.019 0.0187
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0194 0.1454 0.1454
Loa Loa (eye worm) hypothetical protein 0.0471 0.3692 0.369
Brugia malayi ecdysteroid receptor 0.002 0.0052 0.0052
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0069
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.0017 0.0029 0.0029
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0037 0.019 0.019
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Entamoeba histolytica Flap nuclease, putative 0.0029 0.0127 0.1301
Loa Loa (eye worm) hypothetical protein 0.0315 0.2435 0.2433
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Brugia malayi Zinc finger protein 183 homolog 0.0023 0.0072 0.0072
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0111 0.0788 1
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0129 0.0129
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0189 0.1413 0.1413
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0072 0.0206
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Onchocerca volvulus Netrin receptor homolog 0.0016 0.002 0.0016
Onchocerca volvulus 0.0023 0.0072 0.0068
Echinococcus multilocularis tumor protein p63 0.0382 0.2975 0.2975
Loa Loa (eye worm) hypothetical protein 0.0445 0.3486 0.3484
Echinococcus granulosus RING finger protein 185 0.0023 0.0072 0.0072
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0017 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0024 0.0082 0.0079
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0037 0.019 0.019
Onchocerca volvulus 0.0025 0.009 0.0086
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0017 0.0029 0.0083
Loa Loa (eye worm) hypothetical protein 0.003 0.0132 0.0129
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0017 0.0028 0.0028
Brugia malayi hypothetical protein 0.0029 0.0119 0.0119
Schistosoma mansoni hypothetical protein 0.0046 0.0261 0.0261
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0025 0.009 0.009
Brugia malayi putative neuropeptide receptor 0.0051 0.0297 0.0297
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0052 0.0052
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0051 0.0297 0.0293
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0027 0.0105 0.0102
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0161 0.0161
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0315 0.2435 0.2435
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0051 0.0297 0.0297
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0113 0.0802 0.0802
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.1252 1 1
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger) containing protein, putative 0.0023 0.0072 0.0206
Echinococcus granulosus hyperpolarization activated cyclic 0.0037 0.019 0.019
Leishmania major hypothetical protein, conserved 0.0025 0.009 0.0259
Trichomonas vaginalis adenylate cyclase, putative 0.0017 0.0029 0.0029
Giardia lamblia Hypothetical protein 0.0023 0.0072 0.3596
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0119 0.0119
Trypanosoma cruzi hypothetical protein 0.0023 0.0072 0.0206
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0001
Leishmania major hypothetical protein, conserved 0.0023 0.0072 0.0206
Schistosoma mansoni biogenic amine receptor 0.0051 0.0297 0.0297
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0297 0.0297
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0297 0.0297
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0297 0.0297
Trypanosoma cruzi hypothetical protein, conserved 0.0445 0.3486 1
Loa Loa (eye worm) hypothetical protein 0.0445 0.3486 0.3484
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0004 0.0004
Echinococcus multilocularis hyperpolarization activated cyclic 0.0037 0.019 0.019
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0025 0.009 0.009
Brugia malayi Tachykinin-like peptides receptor 99D 0.0051 0.0297 0.0297
Onchocerca volvulus 0.0041 0.0218 0.0213
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.0297 0.0297
Plasmodium vivax RNA helicase-1, putative 0.0024 0.0082 0.0061
Schistosoma mansoni neuropeptide f receptor 76f 0.0051 0.0297 0.0297
Onchocerca volvulus RING finger protein 141 homolog 0.0023 0.0072 0.0068
Echinococcus granulosus death domain containing protein 0.0016 0.002 0.002
Echinococcus multilocularis E3 ubiquitin protein ligase mib1 0.0023 0.0073 0.0073
Echinococcus granulosus tm gpcr rhodopsin 0.0556 0.4376 0.4376
Trichomonas vaginalis adenylate cyclase, putative 0.0017 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Schistosoma mansoni hypothetical protein 0.0445 0.3486 0.3486
Brugia malayi Zinc finger, C2H2 type family protein 0.0023 0.0072 0.0072
Brugia malayi intermediate filament protein 0.003 0.0135 0.0135
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0037 0.019 0.019
Echinococcus multilocularis g-protein coupled receptor 0.0051 0.0297 0.0297
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Mycobacterium leprae PROBABLE HYDROLASE 0.0027 0.0105 0.5635
Leishmania major hypothetical protein, unknown function 0.0025 0.009 0.0259
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Trypanosoma brucei Flagellar Member 6 0.0025 0.009 0.0259
Echinococcus granulosus orexin receptor type 2 0.0051 0.0297 0.0297
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0033 0.0033
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0082 0.0082
Brugia malayi hypothetical protein 0.0051 0.0297 0.0297
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0052 0.0052
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Echinococcus granulosus 7TM GPCR rhodopsin 0.0051 0.0297 0.0297
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0072 0.0072
Brugia malayi Flap endonuclease-1 0.0029 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0025 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0023 0.0072 0.0072
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0024 0.0082 0.6787
Schistosoma mansoni survival motor neuron protein 0.0055 0.0329 0.0329
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0017 0.0028 0.008
Echinococcus multilocularis serotonin receptor 0.0051 0.0297 0.0297
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0033 0.0095
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0049
Brugia malayi hypothetical protein 0.0051 0.0297 0.0297
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0025 0.009 0.7929
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.008 0.0534 0.0534
Giardia lamblia Ser/Thr protein kinase 0.0023 0.0072 0.3596
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0021 0.0018
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0051 0.0297 0.0297
Trichomonas vaginalis adenylate cyclase, putative 0.0017 0.0029 0.0029
Schistosoma mansoni zinc finger protein 0.0023 0.0072 0.0072
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0017 0.0028 0.008
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.002 0.0017
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.0297 0.0297
Trichomonas vaginalis guanylate cyclase beta 1 subunit, putative 0.0017 0.0029 0.0029
Leishmania major hypothetical protein, conserved 0.0023 0.0072 0.0206
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0029 0.0127 0.0363
Mycobacterium ulcerans regulatory protein 0.0025 0.009 0.3122
Brugia malayi Na,K-ATPase alpha subunit 0.0042 0.0228 0.0228
Brugia malayi gamma-secretase subunit aph-1 0.0239 0.1819 0.1819
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0017 0.0028 0.0028
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0004 0.0004
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0017 0.0028 0.008
Echinococcus granulosus bloom syndrome protein 0.0024 0.0084 0.0084
Echinococcus multilocularis GPCR, family 2 0.0018 0.0033 0.0033
Giardia lamblia Protein 21.1 0.0023 0.0072 0.3596
Schistosoma mansoni hypothetical protein 0.1252 1 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0917 0.7294 0.7294
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Trypanosoma brucei cAMP response protein 1, putative 0.0025 0.009 0.0259
Loa Loa (eye worm) hypothetical protein 0.0042 0.0228 0.0224
Trypanosoma cruzi WLM domain containing protein, putative 0.0445 0.3486 1
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0023 0.0072 0.0072
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0052 0.0052
Trichomonas vaginalis adenylate cyclase type vIII, putative 0.0017 0.0029 0.0029
Brugia malayi Niemann-Pick C1 protein precursor 0.0111 0.0788 0.0788
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0189 0.1413 0.1413
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0017 0.0029 0.0029
Mycobacterium leprae Conserved hypothetical protein 0.0025 0.009 0.4802
Loa Loa (eye worm) transcription factor SMAD2 0.0135 0.0979 0.0976
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.006 0.006
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0033 0.0033
Trypanosoma cruzi Aph-1 protein, putative 0.0093 0.0641 0.1839
Leishmania major hypothetical protein, conserved 0.0023 0.0072 0.0206
Giardia lamblia Hypothetical protein 0.0023 0.0072 0.3596
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0023 0.0072 0.0072
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0037 0.019 0.0187
Echinococcus granulosus SWI:SNF matrix associated 0.1252 1 1
Schistosoma mansoni gabp alpha 0.0082 0.055 0.055
Echinococcus multilocularis fmrfamide receptor 0.0051 0.0297 0.0297
Trichomonas vaginalis adenylate cyclase, putative 0.0017 0.0029 0.0029
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Loa Loa (eye worm) brahma associated protein 0.1252 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0072 0.0206
Schistosoma mansoni 60S ribosomal protein L21 0.003 0.0129 0.0129
Brugia malayi Matrixin family protein 0.0022 0.0066 0.0066
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0051 0.0297 0.0294
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0037 0.019 0.019
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0024 0.0082 0.4099
Entamoeba histolytica zinc finger domain containing protein 0.0023 0.0072 0.058
Loa Loa (eye worm) matrix metalloproteinase 0.0022 0.0066 0.0063
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0036 0.0183 0.018
Loa Loa (eye worm) fli-1 protein 0.0249 0.1897 0.1894
Plasmodium vivax flap endonuclease 1, putative 0.0029 0.0127 0.0106
Trypanosoma cruzi WLM domain containing protein, putative 0.0445 0.3486 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.0051 0.0297 0.0293
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0042 0.0228 0.0224
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0069
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.0297 0.0294
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0084 0.0084
Schistosoma mansoni peter pan-related 0.0023 0.0072 0.0072
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Mycobacterium ulcerans hypothetical protein 0.0025 0.009 0.3122
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Echinococcus multilocularis lamin dm0 0.003 0.0135 0.0135
Echinococcus multilocularis nervana 2 0.0194 0.1454 0.1454
Mycobacterium ulcerans transcriptional regulatory protein 0.0025 0.009 0.3122
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0052 0.0052
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.1252 1 1
Echinococcus multilocularis neuropeptide receptor 0.0051 0.0297 0.0297
Echinococcus granulosus nervana 2 0.0194 0.1454 0.1454
Plasmodium vivax zinc finger protein, putative 0.0023 0.0072 0.0051
Echinococcus granulosus sex peptide receptor 0.0051 0.0297 0.0297
Echinococcus multilocularis gamma secretase subunit aph 1 0.0239 0.1819 0.1819
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0033 0.0033
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0033 0.0033
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0037 0.019 0.019
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0055 0.033 0.033
Trypanosoma cruzi Flagellar Member 6 0.0025 0.009 0.0259
Onchocerca volvulus 0.0051 0.0297 0.0293
Onchocerca volvulus Matrix metalloproteinase homolog 0.0049 0.0282 0.0278
Leishmania major eukaryotic initiation factor 4a, putative 0.0024 0.0082 0.0235
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0023 0.0072 0.0206
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0017
Plasmodium vivax calcium-transporting ATPase, putative 0.0017 0.0028 0.0007
Echinococcus granulosus g protein coupled receptor 0.0051 0.0297 0.0297
Onchocerca volvulus 0.0023 0.0072 0.0068
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.019 0.019
Echinococcus granulosus allatostatin A receptor 0.0051 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0051 0.0297 0.0294
Trichomonas vaginalis adenylate cyclase type III, putative 0.0017 0.0029 0.0029
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0445 0.3486 0.3486
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0.0028 0.0028
Trichomonas vaginalis guanylate cyclase, putative 0.0017 0.0029 0.0029
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0042 0.0228 1
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0025 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0056 0.034 0.0337
Schistosoma mansoni hypothetical protein 0.1252 1 1
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0037 0.019 0.019
Schistosoma mansoni intermediate filament proteins 0.003 0.0135 0.0135
Plasmodium vivax E3 ubiquitin-protein ligase RNF5, putative 0.0023 0.0072 0.0051
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0014 0.0004 0.0012
Onchocerca volvulus 0.0034 0.0161 0.0157
Brugia malayi larval opioid receptor 0.0051 0.0297 0.0297
Trichomonas vaginalis adenylate cyclase, putative 0.0017 0.0029 0.0029
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0004 0.0004
Trichomonas vaginalis ankyrin, putative 0.0023 0.0073 0.0073
Brugia malayi steroid hormone receptor 0.002 0.0052 0.0052
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0025 0.009 0.009
Echinococcus granulosus intermediate filament protein 0.003 0.0135 0.0135
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0024 0.0082 0.0082

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 81 uM Inhibition of rabbit skeletal muscle glycogen phosphorylase b assessed as inorganic phosphate release ChEMBL. 25092521
Log Ki (binding) = 4.1 Inhibitory activity against Pig Skeletal Glycogen Phosphorylase b ChEMBL. 12213058

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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