Detailed information for compound 23289

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 642.662 | Formula: C27H45F3N4O10
  • H donors: 6 H acceptors: 7 LogP: -0.8 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 3
  • SMILES: OC(=O)C(F)(F)F.CCCCCN(C[C@@H]([C@@H]1C[C@H]([C@@H](O1)n1ccc(=O)[nH]c1=O)O)O[C@@H]1O[C@@H]([C@H]([C@H]1O)O)CN)CCCCC
  • InChi: 1S/C25H44N4O8.C2HF3O2/c1-3-5-7-10-28(11-8-6-4-2)15-19(37-24-22(33)21(32)18(14-26)36-24)17-13-16(30)23(35-17)29-12-9-20(31)27-25(29)34;3-2(4,5)1(6)7/h9,12,16-19,21-24,30,32-33H,3-8,10-11,13-15,26H2,1-2H3,(H,27,31,34);(H,6,7)/t16-,17+,18-,19+,21-,22-,23-,24+;/m1./s1
  • InChiKey: KPCODNNGOYEHBO-XTWMXOJASA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi DNA topoisomerase II, putative 0.003 0.0119 0.0358
Leishmania major 4-coumarate:coa ligase-like protein 0.0052 0.0254 0.0737
Entamoeba histolytica peptidase, C54 family 0.0026 0.0094 0.1567
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.003 0.0119 0.3165
Loa Loa (eye worm) hypothetical protein 0.0037 0.0159 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0047 0.0245
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0015 0.0028 0.0428
Echinococcus granulosus thyroid hormone receptor alpha 0.0048 0.0226 0.0258
Onchocerca volvulus 0.0075 0.0394 0.13
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0068 0.038
Echinococcus multilocularis tissue type plasminogen activator 0.0019 0.0053 0.0059
Entamoeba histolytica acyl-CoA synthetase, putative 0.0052 0.0254 0.4249
Loa Loa (eye worm) hypothetical protein 0.0101 0.0552 0.055
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0044 0.0048
Leishmania major cathepsin L-like protease 0.0018 0.0047 0.0096
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0365 0.1079
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.0394 0.0453
Trypanosoma brucei heat shock protein, putative 0.003 0.0119 0.0317
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0394 0.0455
Plasmodium falciparum DNA topoisomerase 2 0.003 0.0119 0.557
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0075 0.0394 0.0455
Trypanosoma brucei Heat shock protein 83, putative 0.003 0.0119 0.0317
Trypanosoma cruzi aldo/keto reductase, putative 0.0033 0.0139 0.042
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0039 0.0173 1
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.0394 0.0453
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0043 0.0198 0.0564
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0394 0.0453
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0003 0.002
Brugia malayi hypothetical protein 0.0075 0.0394 0.0966
Echinococcus multilocularis geminin 0.0365 0.2162 0.2494
Onchocerca volvulus 0.0018 0.0047 0.0126
Loa Loa (eye worm) oxidoreductase 0.0033 0.0139 0.0137
Schistosoma mansoni hypothetical protein 0.0365 0.2162 0.2495
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0177 0.2961
Echinococcus multilocularis GA binding protein alpha chain 0.008 0.0423 0.0486
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0016 0.0042
Loa Loa (eye worm) hypothetical protein 0.0101 0.0552 0.055
Plasmodium falciparum phd finger protein, putative 0.0032 0.0131 0.6213
Echinococcus multilocularis sex peptide receptor 0.0075 0.0394 0.0453
Brugia malayi cathepsin L-like precursor 0.0012 0.001 0.0019
Schistosoma mansoni ets-related 0.0243 0.1418 0.1636
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0047 0.0126
Echinococcus multilocularis para nitrobenzyl esterase 0.0013 0.0014 0.0014
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.006 0.0301 0.0736
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0068 0.038
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0075 0.0394 0.0966
Echinococcus multilocularis allatostatin A receptor 0.0075 0.0394 0.0453
Echinococcus granulosus pyruvate kinase 0.0037 0.0159 0.0182
Echinococcus multilocularis serotonin receptor 0.0815 0.4914 0.5672
Schistosoma mansoni zinc finger protein 0.0048 0.0226 0.026
Brugia malayi Ets-domain containing protein 0.008 0.0423 0.1038
Schistosoma mansoni opsin-like receptor 0.0075 0.0394 0.0455
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0101 0.0552 0.1356
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0058 0.0289 0.0883
Loa Loa (eye worm) hypothetical protein 0.0048 0.0226 0.0224
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0012
Entamoeba histolytica pyruvate kinase, putative 0.0026 0.0091 0.1527
Mycobacterium ulcerans hypothetical protein 0.0027 0.01 0.2591
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0128 0.0146
Onchocerca volvulus 0.0013 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Trypanosoma brucei heat shock protein, putative 0.003 0.0119 0.0317
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0011 0.001
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0139 0.0158
Plasmodium falciparum cysteine repeat modular protein 1 0.0019 0.0053 0.2203
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.0394 0.0392
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0159 0.0158
Echinococcus granulosus BC026374 protein S09 family 0.0013 0.0014 0.0014
Echinococcus granulosus orexin receptor type 2 0.0075 0.0394 0.0453
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0022 0.0068 0.0066
Echinococcus multilocularis acetylcholinesterase 0.0077 0.0407 0.0468
Echinococcus granulosus ETS transcription factor Elf 5 0.0012 0.0005 0.0004
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0047 0.0792
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.0835 0.0964
Loa Loa (eye worm) hypothetical protein 0.0101 0.0552 0.055
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0394 0.0453
Echinococcus granulosus survival motor neuron protein 1 0.0261 0.153 0.1764
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.003 0.0119 0.5
Onchocerca volvulus 0.0033 0.0139 0.0436
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.003 0.0119 0.557
Echinococcus granulosus ETS transcription factor Elf 1 0.0012 0.0005 0.0004
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0015 0.0028 0.0428
Leishmania major cathepsin L-like protease 0.007 0.0365 0.1079
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0068 0.016
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0047 0.0046
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0011 0.0003 0.0127
Loa Loa (eye worm) hypothetical protein 0.0028 0.0104 0.0103
Brugia malayi hypothetical protein 0.0075 0.0394 0.0966
Schistosoma mansoni RAR-like nuclear receptor 0.0101 0.0552 0.0637
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0101 0.0552 0.0637
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0011 0.001
Giardia lamblia Pyruvate kinase 0.0037 0.0159 0.1572
Loa Loa (eye worm) oxidoreductase 0.0033 0.0139 0.0137
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0394 0.0455
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0015 0.0028 0.0031
Brugia malayi Pyruvate kinase, muscle isozyme 0.0037 0.0159 0.0388
Echinococcus multilocularis aldo keto reductase 0.0033 0.0139 0.0158
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0116 0.031
Brugia malayi Carboxylesterase family protein 0.0013 0.0014 0.0029
Echinococcus multilocularis aldehyde reductase 0.0024 0.008 0.009
Echinococcus granulosus alkaline phosphatase 0.018 0.1031 0.1189
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0199 0.1561
Leishmania major DNA polymerase kappa, putative 0.0043 0.0198 0.0564
Echinococcus multilocularis heat shock protein 90 0.003 0.0119 0.0135
Trypanosoma brucei DNA polymerase eta, putative 0.0043 0.0198 0.0564
Leishmania major cathepsin L-like protease 0.0018 0.0047 0.0096
Echinococcus granulosus RUN 0.0044 0.0205 0.0234
Brugia malayi ImpB/MucB/SamB family protein 0.0043 0.0198 0.0484
Onchocerca volvulus 0.0013 0.0014 0.0014
Echinococcus multilocularis neuropeptides capa receptor 0.0075 0.0394 0.0453
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0023 0.0077 0.1287
Trichomonas vaginalis aldo/keto reductase, putative 0.0033 0.0139 0.0843
Echinococcus multilocularis alkaline phosphatase 0.018 0.1031 0.1189
Echinococcus multilocularis ecdysone induced protein 78C 0.0101 0.0552 0.0635
Toxoplasma gondii aldose reductase, putative 0.0033 0.0139 0.1087
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0015 0.0028 0.0428
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0101 0.0552 0.055
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0172
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0139 0.0158
Onchocerca volvulus 0.0015 0.0028 0.0062
Brugia malayi heat shock protein 90 0.003 0.0119 0.0287
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.0394 0.0453
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0199 0.124
Echinococcus multilocularis microtubule associated protein 2 0.1429 0.8663 1
Echinococcus multilocularis dna polymerase kappa 0.0043 0.0198 0.0227
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0131 0.1027
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0159 0.0484
Onchocerca volvulus 0.0034 0.014 0.044
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.0394 0.0455
Toxoplasma gondii DNA topoisomerase 2, putative 0.003 0.0119 0.093
Giardia lamblia Aldose reductase 0.0033 0.0139 0.1345
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0047 0.0792
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0101 0.0552 0.0635
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0047 0.0138
Trichomonas vaginalis heat shock protein, putative 0.003 0.0119 0.0711
Brugia malayi hypothetical protein 0.0075 0.0394 0.0966
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0075 0.0394 0.0453
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0344 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0365 0.1079
Onchocerca volvulus 0.0015 0.0028 0.0062
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0044 0.0048
Brugia malayi nuclear receptor NHR-88 0.0048 0.0226 0.0551
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0075 0.0394 0.0453
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0101 0.0552 0.0635
Trichomonas vaginalis aldo-keto reductase, putative 0.0033 0.0139 0.0843
Schistosoma mansoni hypothetical protein 0.0045 0.0209 0.0241
Leishmania major heat shock protein 83-1 0.003 0.0119 0.0317
Mycobacterium leprae Probable two component sensor kinase MprB 0.003 0.0119 0.3996
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0116 0.031
Echinococcus multilocularis survival motor neuron protein 1 0.0261 0.153 0.1764
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0047 0.0245
Loa Loa (eye worm) hypothetical protein 0.0053 0.0261 0.0259
Onchocerca volvulus 0.0053 0.0256 0.0834
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.003 0.0119 1
Schistosoma mansoni neuropeptide receptor 0.0075 0.0394 0.0455
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0131 0.0129
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0075 0.0394 0.0453
Echinococcus granulosus heat shock protein 90 0.003 0.0119 0.0135
Loa Loa (eye worm) ctsf protein 0.0018 0.0047 0.0046
Leishmania major heat shock protein 83-1 0.003 0.0119 0.0317
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0028 0.0428
Echinococcus granulosus allatostatin A receptor 0.0075 0.0394 0.0453
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0065 0.0155
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0094 0.0508 0.0585
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.0394 0.0455
Echinococcus granulosus dnaJ subfamily B 0.0452 0.2694 0.3108
Schistosoma mansoni DNA topoisomerase II 0.003 0.0119 0.0137
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0015 0.0028 0.0428
Brugia malayi CXXC zinc finger family protein 0.0032 0.0128 0.031
Onchocerca volvulus DNA topoisomerase 2 homolog 0.003 0.0119 0.0368
Brugia malayi mbt repeat family protein 0.0053 0.0256 0.0626
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0047 0.0053
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0068 0.0077
Schistosoma mansoni blooms syndrome DNA helicase 0.0011 0.0003 0.0003
Onchocerca volvulus 0.0075 0.0394 0.13
Echinococcus multilocularis aldo keto reductase 0.0033 0.0139 0.0158
Echinococcus granulosus tm gpcr rhodopsin 0.0621 0.373 0.4304
Trypanosoma brucei prostaglandin f synthase 0.0033 0.0139 0.0379
Entamoeba histolytica peptidase, C54 family 0.0026 0.0094 0.1567
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0139 0.0158
Onchocerca volvulus Alhambra homolog 0.0032 0.0131 0.041
Loa Loa (eye worm) hypothetical protein 0.0101 0.0552 0.055
Echinococcus multilocularis thyroid hormone receptor alpha 0.024 0.1401 0.1616
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0256 0.0296
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.016 0.4431
Brugia malayi CHE-14 protein 0.0047 0.0219 0.0536
Loa Loa (eye worm) hypothetical protein 0.0077 0.0407 0.0405
Mycobacterium tuberculosis Two component sensor kinase MprB 0.003 0.0119 0.3165
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0018 0.0043 0.0215
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0058 0.0289 0.0844
Onchocerca volvulus 0.0162 0.0927 0.3104
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0047 0.0245
Echinococcus granulosus geminin 0.0365 0.2162 0.2494
Entamoeba histolytica cysteine protease, putative 0.0018 0.0047 0.0792
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.038 0.1163
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Echinococcus multilocularis nuclear receptor nhr 48 0.0048 0.0226 0.0258
Echinococcus granulosus Niemann Pick C1 protein 0.0109 0.0599 0.0689
Echinococcus granulosus ewsr:fli fusion protein type 0.0012 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0172
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0101 0.0552 0.1356
Plasmodium vivax acetyl-CoA synthetase, putative 0.0015 0.0028 0.1386
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0394 0.0455
Schistosoma mansoni hypothetical protein 0.0045 0.0209 0.0241
Schistosoma mansoni nuclear receptor 0.0048 0.0226 0.026
Echinococcus granulosus carboxylesterase 5A 0.0077 0.0407 0.0468
Trypanosoma cruzi hypothetical protein, conserved 0.0235 0.137 0.4215
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0075 0.0394 0.0392
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0198 0.0564
Trypanosoma brucei pyruvate kinase 1, putative 0.0037 0.0159 0.0443
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0621 0.373 0.4304
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0895 0.5405 0.6238
Echinococcus multilocularis somatostatin receptor 0.0075 0.0394 0.0453
Schistosoma mansoni neuroligin 3 (S09 family) 0.0013 0.0014 0.0016
Brugia malayi RE15519p 0.0075 0.0394 0.0966
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0075 0.0394 0.0392
Loa Loa (eye worm) nuclear receptor NHR-67 0.0048 0.0226 0.0224
Brugia malayi hypothetical protein 0.0053 0.0261 0.0637
Leishmania major heat shock protein 83-1 0.003 0.0119 0.0317
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0028 0.012
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0075 0.0394 0.0966
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0023 0.0077 0.0075
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0012 0.0005 0.0006
Echinococcus granulosus biogenic amine 5HT receptor 0.0815 0.4914 0.5672
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0015 0.0028 0.0428
Brugia malayi Cathepsin L-like precursor 0.0012 0.001 0.0019
Brugia malayi nuclear receptor NHR-67 0.0048 0.0226 0.0551
Loa Loa (eye worm) G-protein coupled receptor 0.0075 0.0394 0.0392
Schistosoma mansoni BC026374 protein (S09 family) 0.0013 0.0014 0.0016
Giardia lamblia Heat shock protein HSP 90-alpha 0.003 0.0119 0.1124
Echinococcus multilocularis neuropeptide receptor 0.0075 0.0394 0.0453
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.0394 0.0392
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0047 0.0245
Loa Loa (eye worm) oxidoreductase 0.0033 0.0139 0.0137
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0289 0.1827
Leishmania major DNA topoisomerase ii 0.003 0.0119 0.0317
Echinococcus granulosus ETS domain containing protein Elk 1 0.0012 0.0005 0.0004
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.003 0.0119 0.0287
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.003 0.0119 0.0711
Brugia malayi ORL1-like opioid receptor 0.0075 0.0394 0.0966
Schistosoma mansoni hypothetical protein 0.0018 0.0044 0.0051
Echinococcus granulosus Nuclear hormone receptor HR96 0.0048 0.0226 0.0258
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0028 0.0428
Entamoeba histolytica acyl-CoA synthetase, putative 0.0052 0.0254 0.4249
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0077 0.0407 0.047
Leishmania major cathepsin L-like protease 0.007 0.0365 0.1079
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0101 0.0552 0.1835
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0027 0.01 0.2591
Chlamydia trachomatis pyruvate kinase 0.0037 0.0159 0.745
Leishmania major DNA polymerase eta, putative 0.0043 0.0198 0.0564
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0075 0.0394 0.0453
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0131 0.6408
Toxoplasma gondii kringle domain-containing protein 0.0019 0.0053 0.0418
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0075 0.0394 0.13
Loa Loa (eye worm) hypothetical protein 0.0043 0.0198 0.0197
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0043 0.0198 0.0229
Plasmodium vivax pyruvate kinase, putative 0.0037 0.0159 0.7794
Schistosoma mansoni hypothetical protein 0.0044 0.0205 0.0236
Echinococcus multilocularis dual specificity protein phosphatase 0.0162 0.0927 0.1068
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0015 0.0028 0.0222
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0139 0.0158
Entamoeba histolytica aldose reductase, putative 0.0033 0.0139 0.2318
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0022 0.0068 0.0077
Schistosoma mansoni biogenic amine (5HT) receptor 0.0815 0.4914 0.5673
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0139 0.0158
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0052 0.0254 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0068 0.0202
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0033 0.0139 0.0379
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.038 0.1125
Mycobacterium tuberculosis Probable sensor protein KdpD 0.003 0.0119 0.3165
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0139 0.0784 0.0903
Schistosoma mansoni gabp alpha 0.008 0.0423 0.0488
Echinococcus granulosus cpg binding protein 0.0034 0.0139 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0101 0.0552 0.1356
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Schistosoma mansoni myelin transcription factor 1 myt1 0.006 0.0301 0.0347
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0198 0.0564
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0048 0.0226 0.0224
Brugia malayi G-protein coupled receptor 0.0075 0.0394 0.0966
Onchocerca volvulus Phospholipase A2 homolog 0.0496 0.2963 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0075 0.0394 0.0455
Brugia malayi Ets-domain containing protein 0.0012 0.0005 0.0007
Brugia malayi Carboxylesterase family protein 0.0013 0.0014 0.0029
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0394 0.0455
Onchocerca volvulus 0.0018 0.0047 0.0126
Echinococcus granulosus fmrfamide receptor 0.0075 0.0394 0.0453
Mycobacterium ulcerans acyl-CoA synthetase 0.0052 0.0254 0.7279
Brugia malayi hypothetical protein 0.0075 0.0394 0.0966
Echinococcus granulosus jumonji domain containing protein 0.0045 0.0208 0.0238
Echinococcus granulosus mitogen activated protein kinase 0.0058 0.0289 0.0332
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0016 0.0042
Onchocerca volvulus 0.0053 0.026 0.0846
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.003 0.0119 0.3165
Echinococcus multilocularis serotonin receptor 0.0815 0.4914 0.5672
Echinococcus granulosus ecdysone induced protein 78C 0.0101 0.0552 0.0635
Trypanosoma cruzi aldo-keto reductase 0.0033 0.0139 0.042
Loa Loa (eye worm) DR-78 0.0048 0.0226 0.0224
Schistosoma mansoni neuropeptide F-like receptor 0.0075 0.0394 0.0455
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0101 0.0552 0.1356
Loa Loa (eye worm) cysteine protease 0.0018 0.0047 0.0046
Plasmodium vivax multidomain scavenger receptor, putative 0.0044 0.0205 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0394 0.0453
Echinococcus multilocularis aldo keto reductase 0.0033 0.0139 0.0158
Toxoplasma gondii pyruvate kinase PyK1 0.0037 0.0159 0.125
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0022 0.0068 0.0077
Mycobacterium leprae Conserved hypothetical protein 0.0024 0.008 0.2267
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Echinococcus multilocularis GPCR, family 2 0.0018 0.0044 0.0048
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0064 0.0327 0.1002
Loa Loa (eye worm) hypothetical protein 0.0048 0.0226 0.0224
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0028 0.0428
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.0344 0.1015
Echinococcus granulosus neuroligin 0.0013 0.0014 0.0014
Echinococcus granulosus peregrin 0.0036 0.0153 0.0175
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.0394 0.0453
Echinococcus multilocularis Niemann Pick C1 protein 0.0109 0.0599 0.0689
Trypanosoma brucei unspecified product 0.003 0.0116 0.031
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0067 0.0343 0.105
Trichomonas vaginalis DNA polymerase eta, putative 0.0043 0.0198 0.1234
Onchocerca volvulus 0.0018 0.0047 0.0126
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0047 0.0245
Entamoeba histolytica peptidase, C54 family 0.0026 0.0094 0.1567
Schistosoma mansoni myosin xvIII 0.0075 0.0394 0.0455
Brugia malayi ecdysone receptor 0.0048 0.0226 0.0551
Loa Loa (eye worm) hypothetical protein 0.0048 0.0226 0.0224
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.003 0.0119 0.3165
Schistosoma mansoni lipoxygenase 0.0113 0.0628 0.0725
Echinococcus multilocularis neuropeptide Y receptor 0.0075 0.0394 0.0453
Trichomonas vaginalis aldo/keto reductase, putative 0.0033 0.0139 0.0843
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0023 0.0077 0.0087
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0013 0.0014 0.0016
Schistosoma mansoni hypothetical protein 0.0019 0.0053 0.0062
Echinococcus granulosus muscleblind protein 0.0165 0.0942 0.1086
Brugia malayi Fli-1 protein 0.0243 0.1418 0.3494
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0199 0.9739
Brugia malayi AMP-binding enzyme family protein 0.0052 0.0254 0.0622
Loa Loa (eye worm) carboxylesterase 0.0077 0.0407 0.0405
Brugia malayi Protein kinase domain containing protein 0.002 0.0058 0.0137
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0189 0.1092 0.3331
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0053 0.0256 0.0834
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0075 0.0394 0.0455
Loa Loa (eye worm) hypothetical protein 0.0165 0.0942 0.0941
Loa Loa (eye worm) hypothetical protein 0.007 0.0364 0.0362
Echinococcus granulosus SAM and MBT domain containing protein 0.0053 0.0256 0.0294
Schistosoma mansoni hypothetical protein 0.0094 0.0508 0.0587
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0047 0.0245
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0101 0.0552 0.1356
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0159 0.0158
Brugia malayi kinase, mitochondrial precursor 0.0542 0.3246 0.8009
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.003 0.0119 0.3165
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0226 0.0258
Brugia malayi tailless protein 0.0048 0.0226 0.0551
Giardia lamblia Aldose reductase 0.0033 0.0139 0.1345
Schistosoma mansoni hypothetical protein 0.0075 0.0394 0.0455
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0198 0.0604
Giardia lamblia Non ATPase subunit MPR1 of 26S proteasome 0.0018 0.0043 0.0292
Loa Loa (eye worm) hypothetical protein 0.0026 0.0091 0.009
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0068 0.2968
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0226 0.026
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.0394 0.0453
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0542 0.3246 1
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0013 0.0016 0.0128
Toxoplasma gondii pyruvate kinase PyKII 0.0019 0.005 0.0391
Brugia malayi MAP kinase sur-1 0.0058 0.0289 0.0707
Plasmodium vivax DNA topoisomerase II, putative 0.003 0.0119 0.5799
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0068 0.038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0365 0.1079
Onchocerca volvulus 0.0013 0.0014 0.0014
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0047 0.0126
Onchocerca volvulus 0.0075 0.0394 0.13
Onchocerca volvulus 0.0075 0.0394 0.13
Schistosoma mansoni rab6-interacting 0.0044 0.0205 0.0236
Schistosoma mansoni hypothetical protein 0.0018 0.0044 0.0051
Leishmania major pyruvate kinase 0.0037 0.0159 0.0443
Schistosoma mansoni gliotactin 0.0013 0.0014 0.0016
Leishmania major heat shock protein 83-1 0.003 0.0119 0.0317
Schistosoma mansoni opsin-like receptor 0.0075 0.0394 0.0455
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.01 0.0258
Loa Loa (eye worm) hypothetical protein 0.0018 0.0047 0.0046
Echinococcus granulosus Peptidase C54 0.0067 0.0343 0.0394
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0075 0.0394 0.0453
Schistosoma mansoni alkaline phosphatase 0.018 0.1031 0.1191
Entamoeba histolytica peptidase, C54 family 0.0026 0.0094 0.1567
Echinococcus multilocularis ephrin type A receptor 4 A 0.0071 0.0369 0.0424
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0026 0.0094 0.0281
Plasmodium vivax pyruvate kinase 2, putative 0.0019 0.005 0.2441
Onchocerca volvulus 0.0018 0.0047 0.0126
Echinococcus granulosus Protein patched homolog 1 0.0047 0.0219 0.0251
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0101 0.0552 0.0635
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0674 0.4052 1
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0028 0.0037
Brugia malayi Cathepsin L-like precursor 0.0012 0.001 0.0019
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0067 0.0343 0.2182
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.016 0.4431
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0289 0.0883
Echinococcus granulosus GPCR family 2 0.0018 0.0044 0.0048
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.006 0.0301 0.0345
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0012
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0028 0.0079
Brugia malayi hypothetical protein 0.0075 0.0394 0.0966
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0047 0.0245
Schistosoma mansoni DNA helicase recq5 0.0022 0.0068 0.0079
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0139 0.0158
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0047 0.0053
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0028 0.0428
Trypanosoma cruzi heat shock protein 85, putative 0.003 0.0119 0.0358
Echinococcus multilocularis protein patched 0.0047 0.0219 0.0251
Giardia lamblia Kinase, CMGC MAPK 0.0058 0.0289 0.2995
Echinococcus granulosus Polycystic kidney disease protein 0.0044 0.0205 0.0234
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0289 0.0334
Leishmania major heat shock protein 83-1 0.003 0.0119 0.0317
Echinococcus granulosus cysteine protease atg4b 0.0067 0.0343 0.0394
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Echinococcus multilocularis lipoxygenase domain containing protein 0.0044 0.0205 0.0234
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0028 0.0428
Leishmania major heat shock protein 83-1 0.003 0.0119 0.0317
Leishmania major prostaglandin f synthase, putative 0.0033 0.0139 0.0379
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0047 0.0245
Echinococcus multilocularis ETS transcription factor Elf 1 0.0012 0.0005 0.0004
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0109 0.0599 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.0344 0.0395
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0053 0.0261 0.0301
Brugia malayi hypothetical protein 0.0261 0.153 0.3771
Onchocerca volvulus 0.0075 0.0394 0.13
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0131 0.0149
Schistosoma mansoni ephrin receptor 0.0071 0.0369 0.0426
Onchocerca volvulus 0.0044 0.0205 0.0659
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Loa Loa (eye worm) hypothetical protein 0.0036 0.0153 0.0151
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0027
Leishmania major pyruvate kinase 0.0037 0.0159 0.0443
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0018 0.0043 0.0215
Onchocerca volvulus 0.0048 0.0226 0.073
Echinococcus granulosus alpha 1A adrenergic receptor 0.0075 0.0394 0.0453
Echinococcus multilocularis mitogen activated protein kinase 3 0.0058 0.0289 0.0332
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0012 0.0005 0.0004
Brugia malayi nuclear hormone receptor 0.0101 0.0552 0.1356
Leishmania major heat shock protein 83-1 0.003 0.0119 0.0317
Onchocerca volvulus 0.0048 0.0226 0.073
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0008
Schistosoma mansoni microtubule-associated protein tau 0.1429 0.8663 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0101 0.0552 0.1356
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0394 0.0453
Mycobacterium leprae Probable pyruvate kinase PykA 0.0037 0.0159 0.5803
Schistosoma mansoni hypothetical protein 0.0075 0.0394 0.0455
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0105 0.0579 0.0666
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.003 0.0119 0.0317
Schistosoma mansoni hypothetical protein 0.0094 0.0508 0.0587
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0344 1
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.003 0.0119 0.3165
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0052 0.0254 0.7279
Entamoeba histolytica aldose reductase, putative 0.0033 0.0139 0.2318
Brugia malayi transcription factor E74 isoform 0.0012 0.0005 0.0007
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.003 0.0119 0.3165
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0013 0.0014 0.0016
Schistosoma mansoni pyruvate dehydrogenase 0.0542 0.3246 0.3747
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0674 0.4052 0.4677
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0052 0.0254 0.7279
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0139 0.0158
Onchocerca volvulus 0.0262 0.1537 0.517
Echinococcus granulosus ephrin type A receptor 4 A 0.0071 0.0369 0.0424
Brugia malayi Carboxylesterase family protein 0.0013 0.0014 0.0029
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0101 0.0552 0.0635
Trichomonas vaginalis heat shock protein, putative 0.003 0.0119 0.0711
Schistosoma mansoni pyruvate kinase 0.0019 0.005 0.0058
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Schistosoma mansoni amine GPCR 0.0075 0.0394 0.0455
Brugia malayi steroid hormone receptor 0.0101 0.0552 0.1356
Loa Loa (eye worm) hypothetical protein 0.0022 0.0068 0.0066
Schistosoma mansoni hypothetical protein 0.0045 0.0209 0.0241
Leishmania major heat shock protein 83-1 0.003 0.0119 0.0317
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0101 0.0552 0.0637
Loa Loa (eye worm) hypothetical protein 0.003 0.0119 0.0117
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0028 0.0428
Mycobacterium ulcerans DNA gyrase subunit B 0.003 0.0119 0.3165
Loa Loa (eye worm) melatonin receptor type 1A 0.0075 0.0394 0.0392
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0101 0.0552 0.0635
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0033 0.0139 0.0843
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0199 0.0228
Onchocerca volvulus 0.0033 0.0139 0.0436
Schistosoma mansoni elf1 0.0012 0.0005 0.0006
Entamoeba histolytica peptidase, C54 family 0.0067 0.0343 0.5732
Loa Loa (eye worm) hypothetical protein 0.0674 0.4052 0.4051
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0047 0.0053
Loa Loa (eye worm) steroid hormone receptor 0.0101 0.0552 0.055
Echinococcus granulosus para nitrobenzyl esterase 0.0013 0.0014 0.0014
Echinococcus multilocularis pyruvate kinase 0.0019 0.005 0.0056
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Plasmodium falciparum pyruvate kinase 2 0.0019 0.005 0.2031
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0013 0.0014 0.0014
Echinococcus granulosus neuropeptide receptor A26 0.0583 0.3497 0.4036
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0172
Echinococcus multilocularis RUN 0.0044 0.0205 0.0234
Echinococcus multilocularis carboxylesterase 5A 0.0077 0.0407 0.0468
Mycobacterium leprae Probable two-component sensor kinase 0.003 0.0119 0.3996
Echinococcus multilocularis ewsr:fli fusion protein type 0.0012 0.0005 0.0004
Schistosoma mansoni amine GPCR 0.0075 0.0394 0.0455
Plasmodium falciparum cysteine protease ATG4, putative 0.0026 0.0094 0.4291
Onchocerca volvulus 0.0033 0.0139 0.0436
Brugia malayi mbt repeat family protein 0.0053 0.0256 0.0626
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Echinococcus multilocularis peregrin 0.0036 0.0153 0.0175
Echinococcus granulosus sterol regulatory element binding protein 0.0047 0.0219 0.0251
Brugia malayi hypothetical protein 0.0044 0.0205 0.0499
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0094 0.0508 0.1249
Plasmodium vivax DNA repair protein REV1, putative 0.0013 0.0016 0.08
Trypanosoma brucei unspecified product 0.003 0.0116 0.031
Leishmania major hypothetical protein, conserved 0.0028 0.0104 0.0273
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0394 0.0453
Trypanosoma brucei heat shock protein, putative 0.003 0.0119 0.0317
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0053 0.0261 0.0299
Brugia malayi Carboxylesterase family protein 0.0077 0.0407 0.0998
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0033 0.0139 0.0336
Loa Loa (eye worm) hypothetical protein 0.0101 0.0552 0.055
Echinococcus multilocularis pyruvate kinase 0.0019 0.005 0.0056
Plasmodium vivax vivapain-2 0.0018 0.0047 0.2317
Brugia malayi GnHR receptor homolog 0.0075 0.0394 0.0966
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0039 0.0173 0.4827
Brugia malayi Bromodomain containing protein 0.0036 0.0153 0.0372
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0028 0.0079
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0104 0.0314
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Toxoplasma gondii cathepsin CPL 0.0018 0.0047 0.0371
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0015 0.0028 0.0428
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0198 0.0564
Loa Loa (eye worm) pyruvate kinase-PB 0.0026 0.0091 0.009
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.001 0.0012
Trypanosoma cruzi major cysteine proteinase, putative 0.0055 0.0273 0.0833
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0073 0.038 0.0378
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0048 0.0226 0.073
Loa Loa (eye worm) hypothetical protein 0.0109 0.0599 0.0597
Mycobacterium tuberculosis Conserved protein 0.0027 0.01 0.2591
Onchocerca volvulus DNA topoisomerase 2 homolog 0.003 0.0119 0.0368
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0047 0.0245
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0047 0.0053
Loa Loa (eye worm) hypothetical protein 0.0044 0.0205 0.0203
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0047 0.0245
Schistosoma mansoni hypothetical protein 0.0012 0.0005 0.0006
Echinococcus granulosus dna polymerase kappa 0.0043 0.0198 0.0227
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0394 0.0455
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0394 0.0453
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0394 0.0453
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0012 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0015
Schistosoma mansoni aldo-keto reductase 0.0033 0.0139 0.016
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0394 0.0453
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0193 0.1114 0.1284
Brugia malayi ecdysteroid receptor 0.0258 0.1514 0.3731
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0067 0.0343 0.2182
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0047 0.0245
Leishmania major cathepsin L-like protease 0.007 0.0365 0.1079
Brugia malayi G-protein coupled receptor 0.0075 0.0394 0.0966
Brugia malayi Nuclear hormone receptor E75 0.0048 0.0226 0.0551
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0015 0.0028 0.0428
Echinococcus granulosus lipoxygenase domain containing protein 0.0044 0.0205 0.0234
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Leishmania major heat shock protein 83-1 0.003 0.0119 0.0317
Brugia malayi hypothetical protein 0.0075 0.0394 0.0966
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0542 0.3246 0.3745
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0047 0.0111
Mycobacterium tuberculosis Probable two component sensor kinase 0.003 0.0119 0.3165
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0047 0.1899
Trypanosoma cruzi hypothetical protein, conserved 0.0235 0.137 0.4215
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0394 0.0453
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0289 0.0883
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0159 0.0979
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.003 0.0119 0.0711
Schistosoma mansoni autophagin-1 (C54 family) 0.0067 0.0343 0.0396
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0394 0.0453
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Loa Loa (eye worm) hypothetical protein 0.0053 0.0261 0.0259
Entamoeba histolytica acyl-coA synthetase, putative 0.0052 0.0254 0.4249
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0028 0.0079
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0192 0.022
Leishmania major 4-coumarate:coa ligase-like protein 0.0052 0.0254 0.0737
Loa Loa (eye worm) TOPoisomerase family member 0.003 0.0119 0.0117
Echinococcus granulosus 7tm_1 domain containing protein 0.0075 0.0394 0.0453
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0101 0.0552 0.1356
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0101 0.0552 0.0635
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0058 0.0289 0.2264
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0177 0.8588
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0015 0.0028 0.0428
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0184 0.0212
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0047 0.0245
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0047 0.0055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0047 0.0245
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.003 0.0119 0.0317
Schistosoma mansoni hypothetical protein 0.0012 0.0011 0.0012
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.018 0.1031 0.1189
Schistosoma mansoni lipoxygenase 0.0193 0.1114 0.1286
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0047 0.0245
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.014 0.0162
Echinococcus granulosus protein C ets 2 0.0012 0.0005 0.0004
Loa Loa (eye worm) TK/ROR protein kinase 0.002 0.0058 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0198 0.0564
Echinococcus multilocularis jumonji domain containing protein 0.0045 0.0208 0.0238
Loa Loa (eye worm) hypothetical protein 0.0067 0.0343 0.0341
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0013 0.0016 0.0128
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0289 0.1827
Echinococcus multilocularis pyruvate kinase 0.0029 0.0112 0.0127
Brugia malayi nuclear receptor RXR 0.0053 0.0261 0.0637
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0047 0.0096
Entamoeba histolytica recQ family DNA helicase 0.0011 0.0003 0.0043
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0048 0.0226 0.026
Echinococcus granulosus acetylcholinesterase 0.0077 0.0407 0.0468
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0073 0.038 0.6344
Mycobacterium ulcerans oxidoreductase 0.0033 0.0139 0.3776
Onchocerca volvulus 0.0019 0.0053 0.0146
Trypanosoma cruzi heat shock protein 85, putative 0.003 0.0119 0.0358
Plasmodium vivax DNA gyrase subunit B, putative 0.003 0.0119 0.5799
Loa Loa (eye worm) hypothetical protein 0.0053 0.0256 0.0254
Onchocerca volvulus 0.0075 0.0394 0.13
Echinococcus multilocularis neuropeptide s receptor 0.0583 0.3497 0.4036
Schistosoma mansoni amine GPCR 0.0075 0.0394 0.0455
Schistosoma mansoni coup transcription factor 0.0101 0.0552 0.0637
Loa Loa (eye worm) hypothetical protein 0.0165 0.0942 0.0941
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.006 0.0301 0.0345
Schistosoma mansoni hypothetical protein 0.0032 0.0131 0.0151
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0067 0.0343 0.0396
Entamoeba histolytica recQ family helicase, putative 0.0022 0.0068 0.1138
Brugia malayi AMP-binding enzyme family protein 0.0052 0.0254 0.0622
Echinococcus granulosus aldo keto reductase 0.0033 0.0139 0.0158
Schistosoma mansoni survival motor neuron protein 0.0053 0.026 0.03
Brugia malayi jmjC domain containing protein 0.0041 0.0184 0.0447
Trichomonas vaginalis endoplasmin, putative 0.003 0.0119 0.0711
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0353 0.0407
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0018 0.0043 0.0048
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Echinococcus multilocularis dro:myosuppressin receptor 0.0075 0.0394 0.0453
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.018 0.1031 0.1189
Brugia malayi hypothetical protein 0.0075 0.0394 0.0966
Mycobacterium ulcerans hypothetical protein 0.0027 0.01 0.2591
Echinococcus granulosus aldehyde reductase 0.0024 0.008 0.009
Schistosoma mansoni pyruvate kinase 0.0037 0.0159 0.0184
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0028 0.0428
Trypanosoma brucei hypothetical protein, conserved 0.0235 0.137 0.419
Echinococcus granulosus bloom syndrome protein 0.0022 0.0068 0.0077
Loa Loa (eye worm) D-ets-2 protein 0.0012 0.0005 0.0004
Schistosoma mansoni neuropeptide receptor 0.0075 0.0394 0.0455
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0289 0.1827
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0365 0.1079
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0075 0.0394 0.0455
Brugia malayi neuropeptide F receptor 0.0075 0.0394 0.0966
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0226 0.0258
Trypanosoma brucei aldo-keto reductase, putative 0.0033 0.0139 0.0379
Loa Loa (eye worm) doublecortin family protein 0.0044 0.0205 0.0203
Schistosoma mansoni alkaline phosphatase 0.018 0.1031 0.1191
Echinococcus granulosus GA binding protein alpha chain 0.008 0.0423 0.0486
Echinococcus granulosus pyruvate kinase 0.0019 0.005 0.0056
Echinococcus granulosus neuropeptide Y receptor 0.0075 0.0394 0.0453
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0105 0.0579 0.0666
Brugia malayi Cathepsin L-like precursor 0.0018 0.0047 0.0111
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0199 0.124
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.023 0.1343 0.1341
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.003 0.0119 0.0711
Loa Loa (eye worm) MBCTL1 0.006 0.0301 0.0299
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0067 0.0343 0.2182
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0094 0.0508 0.0585
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0542 0.3246 0.3745
Echinococcus multilocularis expressed conserved protein 0.0102 0.0558 0.0643
Leishmania major heat shock protein 83-1 0.003 0.0119 0.0317
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0047 0.0055
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0131 0.0149
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0067 0.0343 0.0396
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0022 0.0068 0.2968
Brugia malayi hypothetical protein 0.0013 0.0014 0.0029
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0044 0.0048
Mycobacterium tuberculosis Conserved hypothetical protein 0.0043 0.0198 0.5582
Echinococcus multilocularis aldo keto reductase 0.0033 0.0139 0.0158
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0023 0.0077 0.0087
Schistosoma mansoni hypothetical protein 0.0053 0.026 0.03
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0039 0.0173 0.4827
Giardia lamblia Dual specificity phosphatase, catalytic 0.0162 0.0927 1
Schistosoma mansoni pyruvate kinase 0.0037 0.0159 0.0184
Echinococcus multilocularis cysteine protease 0.0018 0.0047 0.0053
Loa Loa (eye worm) hypothetical protein 0.0053 0.0261 0.0259
Schistosoma mansoni nuclear hormone receptor 0.0101 0.0552 0.0637
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0047 0.0245
Brugia malayi DNA topoisomerase II, alpha isozyme 0.003 0.0119 0.0287
Onchocerca volvulus 0.0052 0.0254 0.0827
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0028 0.0428
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0394 0.0455
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0139 0.0158
Onchocerca volvulus 0.0075 0.0394 0.13
Brugia malayi conserved hypotetical protein 0.0048 0.0226 0.0551
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0159 0.0506
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0365 0.1079
Schistosoma mansoni ets 0.0012 0.0005 0.0006
Brugia malayi Cathepsin L-like cysteine proteinase 0.0012 0.001 0.0019
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0052 0.0254 0.7279
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.018 0.1031 0.1189
Brugia malayi hypothetical protein 0.0075 0.0394 0.0966
Echinococcus granulosus g protein coupled receptor 0.0075 0.0394 0.0453
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0028 0.0428
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.0835 0.0962
Echinococcus multilocularis SAM and MBT domain containing protein 0.0053 0.0256 0.0294
Trypanosoma cruzi heat shock protein 90, putative 0.003 0.0119 0.0358
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0068 0.0162
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0075 0.0394 0.0453
Echinococcus granulosus FTZ F1 alpha 0.0101 0.0552 0.0635
Schistosoma mansoni loxhd1 0.0044 0.0205 0.0236
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0001
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0159 0.0506
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0104 0.0273
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0008
Mycobacterium ulcerans hypothetical protein 0.0052 0.0254 0.7279
Trypanosoma brucei developmentally regulated phosphoprotein 0.0542 0.3246 1
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.003 0.0119 0.0368
Brugia malayi Cathepsin L-like precursor 0.0018 0.0047 0.0111
Echinococcus granulosus sex peptide receptor 0.0075 0.0394 0.0453
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0365 0.1079
Leishmania major heat shock protein 83-1 0.003 0.0119 0.0317
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0033 0.0139 0.0843
Schistosoma mansoni alpha-1 adrenergic receptor 0.0075 0.0394 0.0455
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0047 0.0245
Echinococcus granulosus cathepsin l1 0.0018 0.0047 0.0053
Mycobacterium ulcerans pyruvate kinase 0.0037 0.0159 0.4403
Echinococcus granulosus acetylcholinesterase 0.0077 0.0407 0.0468
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0033 0.0139 0.0336
Loa Loa (eye worm) hypothetical protein 0.0048 0.0226 0.0224
Loa Loa (eye worm) hypothetical protein 0.0542 0.3246 0.3245
Echinococcus multilocularis dna polymerase eta 0.0043 0.0198 0.0227
Echinococcus granulosus G protein coupled receptor 139 0.0075 0.0394 0.0453
Trichomonas vaginalis sensor histidine kinase, putative 0.003 0.0119 0.0711
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0015 0.0028 0.0428
Trypanosoma brucei heat shock protein 90, putative 0.003 0.0119 0.0317
Schistosoma mansoni hypothetical protein 0.0075 0.0394 0.0455
Loa Loa (eye worm) hypothetical protein 0.0032 0.0131 0.0129
Plasmodium falciparum DNA repair protein REV1, putative 0.0013 0.0016 0.03
Echinococcus granulosus hypothetical protein 0.0033 0.0139 0.0158
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0198 0.0564
Schistosoma mansoni opsin-like receptor 0.0075 0.0394 0.0455
Trichomonas vaginalis aldo-keto reductase, putative 0.0033 0.0139 0.0843
Mycobacterium ulcerans acyl-CoA synthetase 0.0052 0.0254 0.7279
Plasmodium falciparum DNA gyrase subunit B 0.003 0.0119 0.557
Brugia malayi Pyruvate kinase, M2 isozyme 0.0037 0.0159 0.0388
Loa Loa (eye worm) hypothetical protein 0.0048 0.0226 0.0224
Brugia malayi Serotonin receptor 0.0075 0.0394 0.0966
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0101 0.0552 0.055
Leishmania major cathepsin L-like protease 0.0018 0.0047 0.0096
Echinococcus multilocularis G protein coupled receptor 139 0.0075 0.0394 0.0453
Echinococcus granulosus dual specificity protein phosphatase 0.0162 0.0927 0.1068
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0101 0.0552 0.055
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0058 0.0289 0.0883
Onchocerca volvulus 0.0033 0.0139 0.0436
Toxoplasma gondii histone lysine methyltransferase SET1 0.0065 0.0331 0.2593
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0208 0.1202 0.1386
Leishmania major hypothetical protein, conserved 0.003 0.0119 0.0317
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0073 0.038 0.0436
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0365 0.1117
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0033 0.0139 0.0336
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0052 0.0254 0.7279
Echinococcus granulosus nuclear receptor nhr 48 0.0048 0.0226 0.0258
Schistosoma mansoni hypothetical protein 0.0039 0.0171 0.0197
Schistosoma mansoni hypothetical protein 0.0012 0.0005 0.0006
Echinococcus granulosus intestinal type alkaline phosphatase 0.018 0.1031 0.1189
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0028 0.0064
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0012
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0058 0.0289 0.0844
Schistosoma mansoni endoplasmin 0.003 0.0119 0.0137
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0033 0.0139 0.0379
Treponema pallidum chemotaxis histidine kinase (cheA) 0.003 0.0119 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0048 0.0226 0.0258
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0101 0.0552 0.055
Trichomonas vaginalis aldo-keto reductase, putative 0.0033 0.0139 0.0843
Trypanosoma brucei protein kinase, putative 0.0058 0.0289 0.0844
Brugia malayi putative neuropeptide receptor 0.0075 0.0394 0.0966
Schistosoma mansoni aldo-keto reductase 0.0033 0.0139 0.016
Brugia malayi putative neuropeptide receptor NPR1 0.0075 0.0394 0.0966
Schistosoma mansoni heat shock protein 0.003 0.0119 0.0137
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0101 0.0552 0.0637
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.038 0.1163
Loa Loa (eye worm) oxidoreductase 0.0033 0.0139 0.0137
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0053 0.0261 0.0259
Echinococcus multilocularis mitogen activated protein kinase 0.0058 0.0289 0.0332
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0075 0.0394 0.0392
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0012
Echinococcus granulosus g protein coupled receptor 0.0075 0.0394 0.0453
Leishmania major heat shock protein 83-1 0.003 0.0119 0.0317
Brugia malayi hypothetical protein 0.0028 0.0104 0.0252
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.003 0.0119 0.3165
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0057 0.028 0.0278
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0394 0.0453
Brugia malayi Cathepsin L-like precursor 0.0018 0.0047 0.0111
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.003 0.0119 0.3996
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0198 0.0564
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0075 0.0394 0.0455
Loa Loa (eye worm) hypothetical protein 0.0048 0.0226 0.0224
Brugia malayi nuclear hormone receptor family member odr-7 0.0048 0.0226 0.0551
Mycobacterium ulcerans acetyl-CoA synthetase 0.0015 0.0028 0.0428
Plasmodium falciparum heat shock protein 90 0.003 0.0119 0.557
Echinococcus multilocularis lipoxygenase domain containing protein 0.0044 0.0205 0.0234
Brugia malayi polk-prov protein 0.0013 0.0016 0.0034
Echinococcus multilocularis polycomb protein SCMH1 0.0053 0.0256 0.0294
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.003 0.0119 0.3996
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0116 0.031
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.018 0.1031 0.1189
Mycobacterium ulcerans putative regultory protein 0.003 0.0119 0.3165
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0289 0.1827
Onchocerca volvulus 0.0033 0.0139 0.0436
Schistosoma mansoni nuclear receptor 0.0048 0.0226 0.026
Echinococcus multilocularis neuropeptide FF receptor 2 0.0075 0.0394 0.0453
Loa Loa (eye worm) hypothetical protein 0.0033 0.0139 0.0137
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0104 0.4841
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0101 0.0552 0.0635
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0094 0.0508 0.0585
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0256 0.0296
Onchocerca volvulus 0.0032 0.0128 0.04
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0028 0.0428
Leishmania major aldo-keto reductase-like protein 0.0033 0.0139 0.0379
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0028 0.0064
Loa Loa (eye worm) hypothetical protein 0.0815 0.4914 0.4913
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0047 0.0219 0.0218
Onchocerca volvulus 0.0075 0.0394 0.13
Onchocerca volvulus 0.007 0.0364 0.1198
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0019 0.0053 0.2605
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0226 0.026
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0022 0.0068 0.0077
Echinococcus multilocularis protein dispatched 1 0.0053 0.026 0.0298
Brugia malayi PHD-finger family protein 0.0032 0.0131 0.0318
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0394 0.0455
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0027 0.01 0.2591
Trichomonas vaginalis aldo-keto reductase, putative 0.0033 0.0139 0.0843
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Onchocerca volvulus 0.0101 0.0552 0.1835
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0094 0.0508 0.0585
Brugia malayi ephrin receptor 1 precursor 0.0034 0.0142 0.0343
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0048 0.0226 0.0258
Plasmodium falciparum acyl-CoA synthetase 0.0039 0.0173 0.8394
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0015 0.0028 0.0428
Echinococcus granulosus lipoxygenase domain containing protein 0.0044 0.0205 0.0234
Schistosoma mansoni hypothetical protein 0.0093 0.0504 0.0582
Giardia lamblia Sgs1 DNA helicase, putative 0.0022 0.0068 0.0569
Loa Loa (eye worm) nuclear hormone receptor 0.0048 0.0226 0.0224
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.0835 0.2056
Echinococcus granulosus serotonin receptor 0.0075 0.0394 0.0453
Giardia lamblia PHD finger protein 15 0.0032 0.0131 0.1261
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0394 0.0455
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0004
Toxoplasma gondii heat shock protein 90, putative 0.003 0.0119 0.093
Trypanosoma brucei DNA topoisomerase II beta, putative 0.003 0.0119 0.0317
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0043 0.0198 0.0227
Loa Loa (eye worm) ets-domain-containing protein 0.0012 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0094 0.0508 0.0507
Onchocerca volvulus 0.0015 0.0028 0.0062
Loa Loa (eye worm) oxidoreductase 0.0033 0.0139 0.0137
Echinococcus multilocularis cysteine protease atg4b 0.0067 0.0343 0.0394
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0018 0.0043 0.0215
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.014 0.1097
Echinococcus multilocularis G-protein coupled receptor, putative 0.0075 0.0394 0.0453
Plasmodium vivax heat shock protein 86, putative 0.003 0.0119 0.5799
Loa Loa (eye worm) RecQ helicase 0.0022 0.0068 0.0066
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0101 0.0552 0.0637
Brugia malayi Cathepsin L-like precursor 0.0018 0.0047 0.0111
Brugia malayi Pre-SET motif family protein 0.0034 0.014 0.034
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0015 0.0028 0.0428
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.003 0.0119 0.0135
Trypanosoma brucei heat shock protein, putative 0.003 0.0119 0.0317
Schistosoma mansoni niemann-pick C1 (NPC1) 0.011 0.0609 0.0703
Brugia malayi Calcitonin receptor-like protein seb-1 0.0057 0.028 0.0685
Echinococcus multilocularis histone acetyltransferase MYST2 0.006 0.0301 0.0345
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0101 0.0552 0.055
Echinococcus multilocularis ETS transcription factor Elf 2 0.0012 0.0005 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0047 0.0245
Trypanosoma brucei DNA topoisomerase ii 0.003 0.0119 0.0317
Loa Loa (eye worm) hypothetical protein 0.0057 0.0284 0.0282
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0053 0.0261 0.0299
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0171 0.0415
Onchocerca volvulus 0.0075 0.0394 0.13
Loa Loa (eye worm) hypothetical protein 0.0101 0.0552 0.055
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0192 0.022
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0043 0.0198 0.5582
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0026 0.0094 0.0735
Brugia malayi Serotonin receptor 0.0075 0.0394 0.0966
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0013 0.0014 0.0016
Loa Loa (eye worm) hypothetical protein 0.0048 0.0226 0.0224
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0026 0.0094 0.024
Mycobacterium tuberculosis Conserved protein 0.003 0.0119 0.3165
Trichomonas vaginalis aldo-keto reductase, putative 0.0033 0.0139 0.0843
Echinococcus multilocularis g-protein coupled receptor 0.0075 0.0394 0.0453
Loa Loa (eye worm) endoplasmin 0.003 0.0119 0.0117
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0043 0.0198 0.0197
Loa Loa (eye worm) hypothetical protein 0.0048 0.0226 0.0224
Echinococcus multilocularis Niemann Pick C1 protein 0.0155 0.0884 0.1018
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0067 0.0343 0.2182
Loa Loa (eye worm) apoptosis regulator protein 0.0094 0.0508 0.0507
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0057 0.028 0.0685
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0208 0.1202 0.1386
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.003 0.0119 0.3165
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0344 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0139 0.0158
Schistosoma mansoni pyruvate dehydrogenase 0.0512 0.3062 0.3534
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0047 0.0245
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0033 0.0139 0.0336
Plasmodium vivax endoplasmin, putative 0.003 0.0119 0.5799
Schistosoma mansoni neuropeptide receptor 0.0075 0.0394 0.0455
Onchocerca volvulus 0.0075 0.0394 0.13
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0184 0.0212
Trypanosoma cruzi DNA polymerase eta, putative 0.0043 0.0198 0.0604
Schistosoma mansoni polycystin 1-related 0.0044 0.0205 0.0236
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0139 0.0158
Schistosoma mansoni steroid hormone receptor ad4bp 0.0101 0.0552 0.0637
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0012
Brugia malayi G protein-coupled receptor F59B2.13 0.0075 0.0394 0.0966
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0026 0.0094 0.024
Entamoeba histolytica deoxycytidyl transferase, putative 0.0043 0.0198 0.3314
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0047 0.0053
Schistosoma mansoni thyroid hormone receptor 0.024 0.1401 0.1617
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0073 0.038 0.0436
Brugia malayi hypothetical protein 0.0075 0.0394 0.0966
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0198 0.0564
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0198 0.0564
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0067 0.0343 0.1012
Onchocerca volvulus Bile acid receptor homolog 0.0258 0.1514 0.5091
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0365 0.1117
Echinococcus granulosus 7TM GPCR rhodopsin 0.0075 0.0394 0.0453
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.0394 0.0453
Loa Loa (eye worm) hypothetical protein 0.0068 0.0352 0.035
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0101 0.0552 0.0635
Trypanosoma brucei heat shock protein, putative 0.003 0.0119 0.0317
Loa Loa (eye worm) dual specificity phosphatase 0.0162 0.0927 0.0925
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0139 0.0158
Leishmania major 4-coumarate:coa ligase-like protein 0.0052 0.0254 0.0737
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0043 0.0198 0.0227
Echinococcus granulosus Nuclear hormone receptor HR96 0.0048 0.0226 0.0258
Echinococcus granulosus heat shock protein 0.003 0.0119 0.0135
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0075 0.0394 0.0453
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.003 0.0119 0.0358
Schistosoma mansoni hypothetical protein 0.0045 0.0209 0.0241
Brugia malayi hypothetical protein 0.0048 0.0226 0.0551
Leishmania major hypothetical protein, conserved 0.0019 0.0053 0.0114
Onchocerca volvulus 0.0075 0.0394 0.13
Onchocerca volvulus 0.0075 0.0394 0.13
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0012 0.0009 0.0008
Giardia lamblia Pms1-like protein 0.003 0.0119 0.1124
Echinococcus granulosus tissue type plasminogen activator 0.0019 0.0053 0.0059
Mycobacterium ulcerans two component sensor kinase MprB 0.003 0.0119 0.3165
Brugia malayi Dopamine receptor protein 2 0.0075 0.0394 0.0966
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0075 0.0394 0.0455
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0365 0.1079
Echinococcus multilocularis pyruvate kinase 0.0037 0.0159 0.0182
Schistosoma mansoni pol-related 0.0033 0.0139 0.016
Loa Loa (eye worm) proteasome 26S subunit 0.0018 0.0043 0.0041
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0067 0.0343 0.1012
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Echinococcus multilocularis Polycystic kidney disease protein 0.0044 0.0205 0.0234
Echinococcus granulosus peptide allatostatin:somatostatin 0.0075 0.0394 0.0453
Trypanosoma cruzi heat shock protein 85, putative 0.003 0.0119 0.0358
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 11, putative 0.0018 0.0043 0.0124
Brugia malayi Melatonin receptor type 1A 0.0075 0.0394 0.0966
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0037 0.0159 0.4403
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0101 0.0552 0.0635
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0104 0.4841
Mycobacterium tuberculosis Probable oxidoreductase 0.0033 0.0139 0.3776
Trypanosoma brucei heat shock protein, putative 0.003 0.0119 0.0317
Brugia malayi Muscleblind-like protein 0.0165 0.0942 0.232
Trypanosoma cruzi DNA polymerase eta, putative 0.0013 0.0016 0.0042
Leishmania major proteasome regulatory non-ATP-ase subunit 11, putative,19S proteasome regulatory subunit, Metallo- peptidase, Clan MP, Family M6 0.0018 0.0043 0.0082
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0058 0.0289 0.0844
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0131 0.0151
Schistosoma mansoni jumonji domain containing protein 0.0084 0.0446 0.0515
Brugia malayi Carboxylesterase family protein 0.0013 0.0014 0.0029
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.003 0.0119 0.0711
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0101 0.0552 0.0637
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0139 0.0158
Mycobacterium ulcerans hypothetical protein 0.0013 0.0016 0.0064
Plasmodium falciparum LCCL domain-containing protein 0.0044 0.0205 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0075 0.0394 0.0453
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.014 0.016
Echinococcus granulosus cathepsin l1 0.0012 0.001 0.001
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0189 0.1092 0.3359
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0015 0.0028 0.0428
Loa Loa (eye worm) hypothetical protein 0.0057 0.028 0.0278
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0067 0.0343 0.2182
Loa Loa (eye worm) hypothetical protein 0.0815 0.4914 0.4913
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0015 0.0028 0.0474
Schistosoma mansoni histamine h1 receptor 0.0075 0.0394 0.0455
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.003 0.0119 0.3165
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0101 0.0552 0.1356
Toxoplasma gondii propionate-CoA ligase 0.0015 0.0028 0.0222
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0101 0.0552 0.0635
Brugia malayi sulfakinin receptor protein 0.0075 0.0394 0.0966
Schistosoma mansoni DNA polymerase eta 0.0043 0.0198 0.0229
Loa Loa (eye worm) oxidoreductase 0.0015 0.0028 0.0027
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0139 0.0158
Plasmodium vivax SET domain protein, putative 0.0034 0.014 0.6845
Entamoeba histolytica DNA topoisomerase II, putative 0.003 0.0119 0.1982
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0365 0.1117
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0012
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0028 0.0064
Brugia malayi hypothetical protein 0.0048 0.0226 0.0551
Echinococcus granulosus polycomb protein SCMH1 0.0053 0.0256 0.0294
Trichomonas vaginalis set domain proteins, putative 0.0262 0.1537 1
Leishmania major cathepsin L-like protease 0.0018 0.0047 0.0096
Trichomonas vaginalis DNA topoisomerase II, putative 0.003 0.0119 0.0711
Loa Loa (eye worm) hypothetical protein 0.0077 0.0407 0.0405
Schistosoma mansoni hypothetical protein 0.0139 0.0784 0.0905
Schistosoma mansoni patched 1 0.0047 0.0219 0.0253
Brugia malayi Cathepsin L-like precursor 0.0018 0.0047 0.0111
Trypanosoma brucei unspecified product 0.0043 0.0198 0.0564
Entamoeba histolytica aldose reductase, putative 0.0033 0.0139 0.2318
Brugia malayi Steroid receptor seven-up type 2 0.0101 0.0552 0.1356
Brugia malayi DNA-binding protein D-ETS-3 0.0012 0.0005 0.0007
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.0261 0.0637
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0139 0.0158
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.003 0.0119 0.3165
Leishmania major heat shock protein 83-1 0.003 0.0119 0.0317
Loa Loa (eye worm) fibroinase 0.0018 0.0047 0.0046
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0011 0.0515
Loa Loa (eye worm) hypothetical protein 0.0015 0.0028 0.0027
Schistosoma mansoni acetylcholinesterase 0.0013 0.0014 0.0016
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0075 0.0394 0.0455
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0159 0.0158
Brugia malayi Dual specificity phosphatase, catalytic domain containing protein 0.0162 0.0927 0.2282
Schistosoma mansoni amine GPCR 0.0075 0.0394 0.0455
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0172
Brugia malayi hypothetical protein 0.0044 0.0205 0.0499
Echinococcus multilocularis cysteine protease 0.0018 0.0047 0.0053
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0193 0.1114 0.1284
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.014 0.016
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0075 0.0394 0.0453
Schistosoma mansoni growth hormone secretagogue receptor 0.0075 0.0394 0.0455
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.003 0.0119 0.5
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.0344 1
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0068 0.016
Schistosoma mansoni endoplasmin 0.003 0.0119 0.0137
Loa Loa (eye worm) hypothetical protein 0.0261 0.153 0.1528
Schistosoma mansoni cpg binding protein 0.0034 0.0139 0.0161
Echinococcus granulosus g-protein coupled receptor 0.0075 0.0394 0.0453
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0159 0.0506
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.014 0.0162
Onchocerca volvulus Neuropeptide F receptor homolog 0.0075 0.0394 0.13
Echinococcus multilocularis sterol regulatory element binding protein 0.0047 0.0219 0.0251
Loa Loa (eye worm) fli-1 protein 0.0243 0.1418 0.1416
Onchocerca volvulus 0.0018 0.0047 0.0126
Loa Loa (eye worm) hypothetical protein 0.0048 0.0226 0.0224
Echinococcus granulosus hypothetical protein 0.0075 0.0394 0.0453
Loa Loa (eye worm) hypothetical protein 0.0055 0.0272 0.027
Loa Loa (eye worm) hypothetical protein 0.0053 0.0261 0.0259
Brugia malayi orphan nuclear receptor NR2E1 0.0048 0.0226 0.0551
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0044 0.0102
Loa Loa (eye worm) hypothetical protein 0.0048 0.0226 0.0224
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.014 0.0162
Trichomonas vaginalis aldo-keto reductase, putative 0.0033 0.0139 0.0843
Brugia malayi Endoplasmin precursor 0.003 0.0119 0.0287
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0047 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0047 0.0245
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0027 0.01 0.0587
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0044 0.0102
Trypanosoma brucei heat shock protein, putative 0.003 0.0119 0.0317
Brugia malayi Dopamine receptor protein 1 0.0075 0.0394 0.0966
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0043 0.0198 0.1234
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0139 0.0158
Loa Loa (eye worm) heat shock protein 90 0.003 0.0119 0.0117
Trichomonas vaginalis receptor histidine kinase, putative 0.003 0.0119 0.0711
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0198 0.0604
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0198 0.0604
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0131 0.1027
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0075 0.0394 0.0453
Schistosoma mansoni heat shock protein 0.003 0.0119 0.0137
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0159 0.0484
Echinococcus multilocularis protein C ets 2 0.0012 0.0005 0.0004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0101 0.0552 0.1356
Brugia malayi Nuclear hormone receptor E75 0.0048 0.0226 0.0551
Brugia malayi photoreceptor-specific nuclear receptor 0.0101 0.0552 0.1356
Mycobacterium tuberculosis Possible two component sensor kinase 0.003 0.0119 0.3165
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0075 0.0394 0.0455
Echinococcus granulosus neuropeptide receptor 0.0075 0.0394 0.0453
Echinococcus granulosus citrate lyase subunit beta protein 0.0027 0.01 0.0113
Brugia malayi hypothetical protein 0.0018 0.0044 0.0103
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0048 0.0226 0.026
Loa Loa (eye worm) hypothetical protein 0.0258 0.1514 0.1512
Onchocerca volvulus Phospholipase A2 homolog 0.0104 0.0572 0.1903
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0028 0.0064
Onchocerca volvulus 0.0018 0.0047 0.0126
Trypanosoma brucei pyruvate kinase 1 0.0037 0.0159 0.0443
Onchocerca volvulus Protein ultraspiracle homolog 0.0101 0.0552 0.1835
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0028 0.012
Echinococcus granulosus histone acetyltransferase KAT2B 0.0143 0.081 0.0933
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0068 0.0162
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.003 0.0119 0.3165
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0015 0.0028 0.0031
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0015 0.0028 0.0222
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0075 0.0394 0.0453
Trypanosoma cruzi heat shock protein 90, putative 0.003 0.0119 0.0358
Brugia malayi PHD-finger family protein 0.0012 0.001 0.0018
Schistosoma mansoni DNA helicase recq1 0.0022 0.0068 0.0079
Brugia malayi Peptidase family C54 containing protein 0.0067 0.0343 0.0841
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0365 0.1079
Loa Loa (eye worm) hypothetical protein 0.0048 0.0226 0.0224
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0159 0.0979
Entamoeba histolytica heat shock protein 90, putative 0.003 0.0119 0.1982
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0075 0.0394 0.0453
Echinococcus multilocularis pyruvate kinase 0.0019 0.005 0.0056
Echinococcus granulosus neuropeptide FF receptor 2 0.0075 0.0394 0.0453
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0047 0.0126
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0054 0.0063
Schistosoma mansoni amine GPCR 0.0075 0.0394 0.0455
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0023 0.0077 0.3426
Brugia malayi Pre-SET motif family protein 0.023 0.1343 0.3309
Echinococcus granulosus microtubule associated protein 2 0.1429 0.8663 1
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0022 0.0068 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0101 0.0552 0.1356
Onchocerca volvulus 0.0075 0.0394 0.13
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.003 0.0119 0.3165
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.0008
Trypanosoma brucei heat shock protein, putative 0.003 0.0119 0.0317
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0394 0.0453
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0219 0.1372
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0047 0.0245
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0052 0.0254 1
Schistosoma mansoni hypothetical protein 0.0365 0.2162 0.2495
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0044 0.0048
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0015 0.0028 0.0428
Loa Loa (eye worm) hypothetical protein 0.0039 0.0171 0.0169
Trypanosoma cruzi DNA damage repair protein, putative 0.0013 0.0016 0.0042
Schistosoma mansoni hypothetical protein 0.0452 0.2694 0.3109
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.003 0.0119 0.093
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0189 0.1092 0.8557
Loa Loa (eye worm) hypothetical protein 0.0101 0.0552 0.055
Plasmodium vivax vivapain-2 0.0018 0.0047 0.2317
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.0261 0.0637
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0198 0.0564
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.026 0.0635
Loa Loa (eye worm) hypothetical protein 0.0674 0.4052 0.4051
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0139 0.0158
Leishmania major acetyl-CoA synthetase, putative 0.0015 0.0028 0.0037
Brugia malayi neuropeptide F receptor 0.0075 0.0394 0.0966
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0048 0.0226 0.073
Trichomonas vaginalis receptor histidine kinase, putative 0.003 0.0119 0.0711
Trypanosoma cruzi DNA damage repair protein, putative 0.0013 0.0016 0.0042
Echinococcus multilocularis neuroligin 0.0013 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0047 0.0219 0.0218
Echinococcus multilocularis ETS transcription factor Elf 5 0.0012 0.0005 0.0004
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0075 0.0394 0.0453
Echinococcus multilocularis neuropeptide receptor A26 0.0583 0.3497 0.4036
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.001 0.0168
Brugia malayi Phospholipase A2 family protein 0.0104 0.0572 0.1406
Brugia malayi Ets-domain containing protein 0.008 0.0423 0.1038
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0198 0.0564
Schistosoma mansoni dual specificity protein phosphatase 0.0162 0.0927 0.107
Brugia malayi Niemann-Pick C1 protein precursor 0.0109 0.0599 0.1472
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0341 0.0339
Brugia malayi AKH receptor 0.0075 0.0394 0.0966
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0101 0.0552 0.1356
Loa Loa (eye worm) hypothetical protein 0.0039 0.0173 0.0172
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0198 0.0604
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0018 0.0043 0.0048
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0058 0.0289 0.0287
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0075 0.0394 0.0453
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0139 0.0158
Echinococcus multilocularis Peptidase C54 0.0067 0.0343 0.0394
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0394 0.0453
Schistosoma mansoni cpg binding protein 0.0034 0.0139 0.0161
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0101 0.0552 0.0635
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0018 0.0043 0.0082
Brugia malayi jmjC domain containing protein 0.0105 0.0579 0.1423
Schistosoma mansoni biogenic amine receptor 0.0075 0.0394 0.0455
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0047 0.0245
Loa Loa (eye worm) hypothetical protein 0.0048 0.0226 0.0224
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0365 0.1079
Echinococcus multilocularis orexin receptor type 2 0.0075 0.0394 0.0453
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.014 0.0162
Echinococcus granulosus neuropeptides capa receptor 0.0075 0.0394 0.0453
Leishmania major heat shock protein 83-1 0.003 0.0119 0.0317
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0052 0.0254 0.7279
Schistosoma mansoni hypothetical protein 0.0094 0.0508 0.0587
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0075 0.0394 0.0966
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0015 0.0028 0.0037
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0094 0.0508 0.0587
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0198 0.5582
Echinococcus multilocularis acetylcholinesterase 0.0077 0.0407 0.0468
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0128 0.0126
Schistosoma mansoni thyroid hormone receptor 0.024 0.1401 0.1617
Echinococcus multilocularis intestinal type alkaline phosphatase 0.018 0.1031 0.1189
Brugia malayi nuclear hormone receptor 0.0048 0.0226 0.0551
Echinococcus multilocularis citrate lyase subunit beta protein 0.0027 0.01 0.0113
Trichomonas vaginalis aldo-keto reductase, putative 0.0033 0.0139 0.0843
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0254 0.7279
Onchocerca volvulus 0.0013 0.0014 0.0014
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0344 0.0397
Echinococcus multilocularis cpg binding protein 0.0034 0.0139 0.0159
Trypanosoma brucei heat shock protein 90, putative 0.003 0.0119 0.0317
Trichomonas vaginalis aldo-keto reductase, putative 0.0033 0.0139 0.0843
Echinococcus granulosus pyruvate kinase 0.0037 0.0159 0.0182
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0028 0.0037
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Echinococcus granulosus histone acetyltransferase MYST2 0.006 0.0301 0.0345
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0104 0.0819
Echinococcus multilocularis ETS transcription factor Elf 2 0.0012 0.0005 0.0004
Leishmania major developmentally regulated phosphoprotein-like protein 0.0542 0.3246 1
Echinococcus granulosus pyruvate kinase 0.0019 0.005 0.0056
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0028 0.0428
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.003 0.0119 0.0358
Onchocerca volvulus 0.0013 0.0014 0.0014
Onchocerca volvulus 0.0015 0.0028 0.0062
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0028 0.0027
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0075 0.0394 0.0453
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.003 0.0119 0.5
Leishmania major cathepsin L-like protease 0.0018 0.0047 0.0096
Brugia malayi Doublecortin family protein 0.0044 0.0205 0.0499
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0365 0.1079
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.003 0.0119 0.3165
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0023 0.0077 0.0184
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0101 0.0552 0.0635
Giardia lamblia Pyruvate kinase 0.0019 0.005 0.0369
Brugia malayi nuclear receptor NHR-88 0.0101 0.0552 0.1356
Echinococcus granulosus pyruvate kinase 0.0019 0.005 0.0056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0101 0.0552 0.055
Schistosoma mansoni pyruvate dehydrogenase 0.0512 0.3062 0.3534
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.01 0.0299
Onchocerca volvulus 0.0075 0.0394 0.13
Leishmania major mitochondrial DNA topoisomerase II 0.003 0.0119 0.0317
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0104 0.0314
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0198 0.0564
Loa Loa (eye worm) acetylcholinesterase 1 0.0077 0.0407 0.0405
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0139 0.0784 0.0903
Trichomonas vaginalis spcc417.12 protein, putative 0.0013 0.0014 0.0028
Trichomonas vaginalis aldo-keto reductase, putative 0.0033 0.0139 0.0843
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Brugia malayi Dopamine receptor 0.0075 0.0394 0.0966
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0068 0.0534
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0028 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0394 0.0455
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Brugia malayi Cathepsin L-like precursor 0.0018 0.0047 0.0111
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Schistosoma mansoni retinoic acid receptor RXR 0.0101 0.0552 0.0637
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0044 0.0042
Schistosoma mansoni rab6-interacting 0.0044 0.0205 0.0236
Loa Loa (eye worm) hypothetical protein 0.0052 0.0254 0.0253
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0139 0.0158
Schistosoma mansoni ets-related 0.0012 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.032 0.1891 0.2182
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0027 0.01 0.2591
Loa Loa (eye worm) hypothetical protein 0.0034 0.014 0.0138
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0027 0.01 0.2591
Brugia malayi hypothetical protein 0.0053 0.0261 0.0637
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.022 0.1276 1
Trypanosoma cruzi DNA topoisomerase II, putative 0.003 0.0119 0.0358
Loa Loa (eye worm) neuropeptide F receptor 0.0075 0.0394 0.0392
Trichomonas vaginalis aldo-keto reductase, putative 0.0033 0.0139 0.0843
Echinococcus granulosus mitogen activated protein kinase 3 0.0058 0.0289 0.0332
Echinococcus multilocularis heat shock protein 0.003 0.0119 0.0135
Brugia malayi G protein-coupled receptor 0.0075 0.0394 0.0966
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0026 0.0094 0.0281
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0018 0.0043 0.0082
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.0344 0.0395
Echinococcus multilocularis lysine specific demethylase 5A 0.0039 0.0173 0.0197
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0047 0.1899
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0012 0.0005 0.0004
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0068 0.0534
Brugia malayi AMP-binding enzyme family protein 0.0052 0.0254 0.0622
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0073 0.038 0.0932
Brugia malayi larval opioid receptor 0.0075 0.0394 0.0966
Onchocerca volvulus 0.0018 0.0047 0.0126
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0048 0.0226 0.0258
Brugia malayi follicle stimulating hormone receptor 0.0075 0.0394 0.0966
Schistosoma mansoni cpg binding protein 0.0032 0.0128 0.0148
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0012
Echinococcus multilocularis BC026374 protein (S09 family) 0.0013 0.0014 0.0014
Leishmania major hypothetical protein, conserved 0.0235 0.137 0.419
Loa Loa (eye worm) TYRA-2 protein 0.0075 0.0394 0.0392
Loa Loa (eye worm) hypothetical protein 0.0052 0.0254 0.0253
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0013 0.0016 0.0128
Trichomonas vaginalis aldo/keto reductase, putative 0.0033 0.0139 0.0843
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0053 0.0256 0.0296
Loa Loa (eye worm) carboxylesterase 0.0013 0.0014 0.0012
Schistosoma mansoni nuclear receptor nhr-48 0.0048 0.0226 0.026
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.01 0.0299
Echinococcus granulosus neuropeptide s receptor 0.0583 0.3497 0.4036
Plasmodium vivax acyl-CoA synthetase, putative 0.0039 0.0173 0.8477
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0052
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0033 0.0139 0.4887
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0001
Onchocerca volvulus 0.0075 0.0394 0.13
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0047 0.0046
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.003 0.0119 0.3165
Schistosoma mansoni acetyl-CoA synthetase 0.0015 0.0028 0.0033
Giardia lamblia DINP protein human, muc B family 0.0043 0.0198 0.2
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0048 0.0226 0.0258
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0033 0.0139 0.0843
Schistosoma mansoni neuropeptide f receptor 76f 0.0075 0.0394 0.0455
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0023 0.0077 0.0184
Onchocerca volvulus 0.0044 0.0205 0.0659
Trichomonas vaginalis aldo-keto reductase, putative 0.0033 0.0139 0.0843
Toxoplasma gondii heat shock protein HSP90 0.003 0.0119 0.093
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0101 0.0552 0.055
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0101 0.0552 0.0637
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0012 0.0005 0.0004
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0047 0.1899
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0177 0.1767
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0394 0.0453
Leishmania major heat shock protein 83-1 0.003 0.0119 0.0317
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.0344 0.2696
Brugia malayi ImpB/MucB/SamB family protein 0.0043 0.0198 0.0484
Echinococcus multilocularis dnaJ subfamily B 0.0452 0.2694 0.3108
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0075 0.0394 0.0392
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0075 0.0394 0.0966
Echinococcus granulosus Niemann Pick C1 protein 0.0155 0.0884 0.1018
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0542 0.3246 0.3745
Mycobacterium ulcerans two component regulator - sensor kinase 0.003 0.0119 0.3165
Brugia malayi Carboxylesterase family protein 0.0077 0.0407 0.0998
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0394 0.0453
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0075 0.0394 0.0392
Onchocerca volvulus 0.0033 0.0139 0.0436
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0365 0.1079
Echinococcus multilocularis rhodopsin orphan GPCR 0.0075 0.0394 0.0453
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.003 0.0119 0.3165
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.016 0.4431
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0184 0.0182
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0068 0.0162
Echinococcus granulosus aldo keto reductase 0.0033 0.0139 0.0158
Loa Loa (eye worm) TK/EPH protein kinase 0.009 0.0486 0.0485
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0344 0.0397
Brugia malayi nuclear receptor RXR 0.0048 0.0226 0.0551
Echinococcus granulosus ETS transcription factor Elf 2 0.0012 0.0005 0.0004
Echinococcus multilocularis muscleblind protein 0.0165 0.0942 0.1086
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0394 0.0455
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0075 0.0394 0.0455
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0198 0.5582
Loa Loa (eye worm) hypothetical protein 0.0104 0.0572 0.057
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0101 0.0552 0.0635
Schistosoma mansoni apoptosis regulator bax 0.0094 0.0508 0.0587
Schistosoma mansoni neuropeptide receptor 0.0075 0.0394 0.0455
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0028 0.0079
Brugia malayi Kringle domain containing protein 0.0019 0.0053 0.0125
Schistosoma mansoni biogenic amine receptor 0.0075 0.0394 0.0455
Onchocerca volvulus 0.0075 0.0394 0.13
Schistosoma mansoni biogenic amine receptor 0.0075 0.0394 0.0455
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0139 0.0158
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0028 0.0064
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0013 0.0015 0.0032
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0013 0.0014 0.0014
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.016 0.4431
Echinococcus granulosus DNA topoisomerase 2 alpha 0.003 0.0119 0.0135
Loa Loa (eye worm) hypothetical protein 0.0052 0.0254 0.0253
Echinococcus multilocularis g protein coupled receptor 0.0075 0.0394 0.0453
Brugia malayi Nuclear hormone receptor-like 1 0.0101 0.0552 0.1356
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.003 0.0119 0.0358
Echinococcus granulosus rhodopsin orphan GPCR 0.0075 0.0394 0.0453
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0198 0.0564
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.008 0.0423 0.0421
Brugia malayi nuclear hormone receptor family member nhr-6 0.0048 0.0226 0.0551
Loa Loa (eye worm) hypothetical protein 0.0018 0.0044 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0053 0.0156
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.014 0.016
Echinococcus multilocularis fmrfamide receptor 0.0075 0.0394 0.0453
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0075 0.0394 0.0455
Echinococcus granulosus dna polymerase eta 0.0043 0.0198 0.0227
Schistosoma mansoni adenoreceptor 0.0075 0.0394 0.0455
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0047 0.0245
Entamoeba histolytica heat shock protein 90, putative 0.003 0.0119 0.1982
Plasmodium falciparum endoplasmin, putative 0.003 0.0119 0.557
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0015 0.0028 0.0428
Brugia malayi Probable DNA topoisomerase II 0.003 0.0119 0.0287
Trypanosoma cruzi Heat shock protein 83, putative 0.003 0.0119 0.0358
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0015 0.0028 0.0428
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0199 0.1561
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0047 0.0053
Echinococcus multilocularis muscleblind protein 1 0.0165 0.0942 0.1086
Echinococcus multilocularis FTZ F1 alpha 0.0101 0.0552 0.0635
Loa Loa (eye worm) hypothetical protein 0.0053 0.0261 0.0259
Echinococcus granulosus somatostatin receptor 0.0075 0.0394 0.0453
Toxoplasma gondii proteasome regulatory subunit 0.0023 0.0077 0.0604
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0075 0.0394 0.0453
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.003 0.0119 0.3165
Trypanosoma cruzi cruzipain precursor, putative 0.007 0.0365 0.1117
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0023 0.0077 0.3765
Echinococcus granulosus lysine specific demethylase 5A 0.0041 0.0184 0.021
Leishmania major heat shock protein 83-1 0.003 0.0119 0.0317
Loa Loa (eye worm) hypothetical protein 0.003 0.0119 0.0117
Plasmodium vivax hypothetical protein, conserved 0.003 0.0119 0.5799
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0073 0.038 0.0438
Loa Loa (eye worm) carboxylesterase 0.0013 0.0014 0.0012
Schistosoma mansoni hypothetical protein 0.0075 0.0394 0.0455
Leishmania major heat shock protein 83-1 0.003 0.0119 0.0317
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0101 0.0552 0.1356
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.003 0.0119 0.093
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.003 0.0119 0.3165
Echinococcus granulosus ETS transcription factor Elf 2 0.0012 0.0005 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0047 0.0245
Loa Loa (eye worm) hypothetical protein 0.0044 0.0205 0.0203
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.003 0.0119 0.0711
Echinococcus granulosus tm gpcr rhodopsin 0.0075 0.0394 0.0453
Schistosoma mansoni DNA polymerase IV / kappa 0.0013 0.0016 0.0019
Echinococcus granulosus expressed conserved protein 0.0102 0.0558 0.0643
Loa Loa (eye worm) hypothetical protein 0.0496 0.2963 0.2962
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0104 0.5106
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0198 0.0564
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0075 0.0394 0.0453
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0028 0.0027
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0028 0.0428
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Echinococcus granulosus dro:myosuppressin receptor 0.0075 0.0394 0.0453
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0053 0.0261 0.0301
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0047 0.0245
Plasmodium falciparum pyruvate kinase 0.0037 0.0159 0.7674
Echinococcus granulosus g protein coupled receptor 0.0075 0.0394 0.0453
Trichomonas vaginalis aldo-keto reductase, putative 0.0033 0.0139 0.0843
Loa Loa (eye worm) acetyltransferase 0.0147 0.0835 0.0833
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0048 0.0226 0.0258
Echinococcus multilocularis neuropeptide receptor 0.0075 0.0394 0.0453
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Schistosoma mansoni hypothetical protein 0.0018 0.0044 0.0051
Mycobacterium ulcerans acyl-CoA synthetase 0.0052 0.0254 0.7279
Echinococcus granulosus aldo keto reductase 0.0033 0.0139 0.0158
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Loa Loa (eye worm) hypothetical protein 0.006 0.0301 0.0299
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0189 0.1092 0.3331
Loa Loa (eye worm) hypothetical protein 0.0048 0.0226 0.0224
Schistosoma mansoni terminal deoxycytidyl transferase 0.0043 0.0198 0.0229
Onchocerca volvulus 0.0075 0.0394 0.13
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0139 0.0158
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0101 0.0552 0.1356
Echinococcus granulosus neuropeptide receptor 0.0075 0.0394 0.0453
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0073 0.038 0.1125
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Echinococcus granulosus tachykinin peptides receptor 99D 0.0075 0.0394 0.0453
Echinococcus multilocularis fmrfamide receptor 0.0075 0.0394 0.0453
Echinococcus multilocularis pyruvate kinase 0.0037 0.0159 0.0182
Echinococcus granulosus tm gpcr rhodopsin 0.0075 0.0394 0.0453
Echinococcus granulosus biogenic amine 5HT receptor 0.0075 0.0394 0.0453
Schistosoma mansoni biogenic amine (5HT) receptor 0.0075 0.0394 0.0455
Loa Loa (eye worm) mbt repeat family protein 0.0053 0.0256 0.0254
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0015 0.0028 0.0064
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0013 0.0014 0.0028
Brugia malayi Tachykinin-like peptides receptor 99D 0.0075 0.0394 0.0966
Brugia malayi hypothetical protein 0.0075 0.0394 0.0966
Loa Loa (eye worm) hypothetical protein 0.0075 0.0394 0.0392
Schistosoma mansoni hypothetical protein 0.0018 0.0044 0.0051
Echinococcus multilocularis ets variant gene 4 0.0012 0.0005 0.0004
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0015 0.0028 0.0918
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0048 0.0226 0.0551

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 9.7 uM Inhibitory activity against Translocase I ChEMBL. 11934590

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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