Detailed information for compound 255414

Basic information

Technical information
  • TDR Targets ID: 255414
  • Name: 1-[(2S)-1-chloropropan-2-yl]-3-(4-iodophenyl) urea
  • MW: 338.573 | Formula: C10H12ClIN2O
  • H donors: 2 H acceptors: 1 LogP: 2.6 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: ClC[C@@H](NC(=O)Nc1ccc(cc1)I)C
  • InChi: 1S/C10H12ClIN2O/c1-7(6-11)13-10(15)14-9-4-2-8(12)3-5-9/h2-5,7H,6H2,1H3,(H2,13,14,15)/t7-/m0/s1
  • InChiKey: AKFJMJCPLGBEPB-ZETCQYMHSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-[(1S)-2-chloro-1-methyl-ethyl]-3-(4-iodophenyl)urea
  • 1-[(1S)-2-chloro-1-methylethyl]-3-(4-iodophenyl)urea

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) calpain family protein 1 0.0041 0.0202 0.0201
Brugia malayi cathepsin L precursor 0.0036 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0203 0.0444
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0189 0.0189
Schistosoma mansoni neurotransmitter gated ion channel 0.0025 0.008 0.0154
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0013 0.0013
Onchocerca volvulus 0.0059 0.034 0.1732
Echinococcus multilocularis fat cadherin tumor suppressor 0.003 0.0114 0.0138
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0054 0.0303 0.0303
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0093 0.06 0.116
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0047 0.0047
Loa Loa (eye worm) melatonin receptor type 1A 0.0093 0.06 0.06
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0124 0.0151
Loa Loa (eye worm) cysteine protease 0.0114 0.0762 0.0761
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0047 0.0142
Giardia lamblia Cysteine protease 0.0036 0.016 0.078
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0093 0.06 0.06
Loa Loa (eye worm) hypothetical protein 0.0024 0.0074 0.0073
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.022
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0054 0.0303 0.0367
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0025 0.008 0.0096
Onchocerca volvulus 0.0054 0.0303 0.1509
Onchocerca volvulus 0.0029 0.0112 0.0351
Echinococcus granulosus alpha 1A adrenergic receptor 0.0093 0.06 0.0726
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.06 0.0726
Loa Loa (eye worm) hypothetical protein 0.0029 0.0112 0.0111
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0079 0.049 0.0594
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0047 0.022
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0025 0.008 0.0079
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0092 0.0588 0.0588
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Toxoplasma gondii EGF family domain-containing protein 0.003 0.0114 0.0468
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0013
Schistosoma mansoni biogenic amine receptor 0.0093 0.06 0.116
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0049 0.0227
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0045 0.0045
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0036 0.016 0.2099
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0093 0.06 0.0726
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0054 0.0303 0.0303
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0124 0.0151
Echinococcus granulosus g protein coupled receptor 0.0093 0.06 0.0726
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0026 0.009 0.0089
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0054 0.0303 0.0586
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0054 0.0303 0.0586
Loa Loa (eye worm) hypothetical protein 0.0025 0.008 0.0079
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0036 0.016 0.1815
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Leishmania major cathepsin L-like protease 0.0114 0.0762 0.3577
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0047 0.0091
Echinococcus multilocularis calpain family protein 1, d 0.0041 0.0202 0.0244
Brugia malayi Cathepsin L-like precursor 0.0032 0.0132 0.0131
Loa Loa (eye worm) animal heme peroxidase 0.0092 0.0588 0.0588
Echinococcus granulosus biogenic amine 5HT receptor 0.0093 0.06 0.0726
Loa Loa (eye worm) matrix metalloproteinase 0.0022 0.0054 0.0053
Plasmodium falciparum cysteine proteinase falcipain 1 0.0068 0.0404 0.5133
Echinococcus granulosus neuropeptides capa receptor 0.0093 0.06 0.0726
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0049 0.0106
Schistosoma mansoni importin beta-1 0.0028 0.0101 0.0196
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0303 0.0303
Onchocerca volvulus 0.003 0.0114 0.0365
Loa Loa (eye worm) glutaminase 0.0265 0.1911 0.1911
Schistosoma mansoni hypothetical protein 0.0331 0.2416 0.467
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0114 0.0762 0.3577
Brugia malayi hypothetical protein 0.0025 0.008 0.0079
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.016 0.0617
Onchocerca volvulus Putative nachr subunit 0.0054 0.0303 0.1509
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0124 0.0428
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Onchocerca volvulus Neurogenic locus notch homolog 0.003 0.0114 0.0365
Brugia malayi Blistered cuticle protein 3 0.0092 0.0588 0.0588
Loa Loa (eye worm) hypothetical protein 0.0018 0.0027 0.0026
Echinococcus granulosus neuropeptide receptor 0.0093 0.06 0.0726
Brugia malayi nuclear receptor RXR 0.0016 0.0013 0.0013
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0054 0.0303 0.0303
Schistosoma mansoni cpg binding protein 0.0066 0.0395 0.0764
Loa Loa (eye worm) hypothetical protein 0.0027 0.0096 0.0096
Entamoeba histolytica hypothetical protein 0.0036 0.016 0.2099
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Echinococcus granulosus fibropellin Ia 0.003 0.0114 0.0138
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0303 0.0303
Schistosoma mansoni cpg binding protein 0.0059 0.034 0.0658
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0195 0.1378 0.8003
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0054 0.0303 0.0303
Echinococcus granulosus calpain 7 C02 family 0.0021 0.0049 0.0059
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0231 0.0279
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0189 0.0823
Echinococcus multilocularis g protein coupled receptor 0.0093 0.06 0.0726
Entamoeba histolytica cysteine protease, putative 0.0068 0.0404 0.5302
Echinococcus multilocularis fmrfamide receptor 0.0093 0.06 0.0726
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0114 0.0762 0.384
Brugia malayi Matrixin family protein 0.0022 0.0054 0.0053
Echinococcus multilocularis dnaJ subfamily B 0.0442 0.3265 0.3953
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0124 0.0151
Brugia malayi Melatonin receptor type 1A 0.0093 0.06 0.06
Schistosoma mansoni hypothetical protein 0.0093 0.06 0.116
Loa Loa (eye worm) hypothetical protein 0.0029 0.0112 0.0111
Brugia malayi cathepsin B-like cysteine proteinase 0.0612 0.4561 0.4561
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0124 0.0124
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0054 0.0303 0.0303
Schistosoma mansoni hypothetical protein 0.0035 0.0158 0.0305
Trypanosoma cruzi major cysteine proteinase, putative 0.0036 0.016 0.035
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0189 0.2211
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.06 0.116
Loa Loa (eye worm) animal heme peroxidase 0.0092 0.0588 0.0588
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.06 0.0726
Brugia malayi Calcitonin receptor-like protein seb-1 0.0103 0.0677 0.0676
Entamoeba histolytica cysteine protease, putative 0.0068 0.0404 0.5302
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0137 0.0166
Toxoplasma gondii cathepsin CPC2 0.0036 0.016 0.078
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0074 0.0073
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Onchocerca volvulus 0.0114 0.0762 0.4277
Brugia malayi Glutamate receptor 1 precursor 0.0027 0.0095 0.0095
Echinococcus multilocularis nAChR subunit 0.0029 0.0112 0.0135
Plasmodium falciparum serine repeat antigen 7 0.0036 0.016 0.1815
Brugia malayi sulfakinin receptor protein 0.0093 0.06 0.06
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0036 0.016 0.078
Echinococcus multilocularis neuropeptide Y receptor 0.0093 0.06 0.0726
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0093 0.06 0.116
Onchocerca volvulus 0.003 0.0114 0.0365
Echinococcus granulosus calpain 0.0021 0.0049 0.0059
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0036 0.016 0.1815
Brugia malayi Glutamate receptor 2 precursor 0.0027 0.0095 0.0095
Onchocerca volvulus Matrix metalloproteinase homolog 0.0048 0.0255 0.1219
Brugia malayi Cadherin domain containing protein 0.003 0.0114 0.0114
Echinococcus granulosus tm gpcr rhodopsin 0.0093 0.06 0.0726
Echinococcus multilocularis neuropeptides capa receptor 0.0093 0.06 0.0726
Schistosoma mansoni notch 0.003 0.0114 0.022
Echinococcus granulosus 7tm_1 domain containing protein 0.0093 0.06 0.0726
Brugia malayi hypothetical protein 0.0243 0.1742 0.1741
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0036 0.016 0.2099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.06 0.116
Onchocerca volvulus 0.0092 0.0588 0.3228
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0189 0.2211
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0035 0.0153 0.0185
Loa Loa (eye worm) hypothetical protein 0.0031 0.0124 0.0124
Trypanosoma cruzi cysteine peptidase, putative 0.0114 0.0762 0.1669
Loa Loa (eye worm) hypothetical protein 0.0026 0.009 0.0089
Giardia lamblia Cathepsin B precursor 0.0036 0.016 0.078
Echinococcus multilocularis slit 2 protein 0.003 0.0114 0.0138
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0056 0.0314 0.0607
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0029 0.0112 0.0111
Onchocerca volvulus 0.0093 0.06 0.33
Loa Loa (eye worm) hypothetical protein 0.0029 0.0112 0.0111
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Loa Loa (eye worm) hypothetical protein 0.0032 0.0132 0.0131
Onchocerca volvulus 0.0093 0.06 0.33
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Plasmodium falciparum serine repeat antigen 1 0.0036 0.016 0.1815
Brugia malayi hypothetical protein 0.0016 0.0013 0.0013
Schistosoma mansoni nAChR subunit 0.0054 0.0303 0.0586
Giardia lamblia Cysteine protease 0.0036 0.016 0.078
Echinococcus multilocularis snurportin 1 0.0298 0.2166 0.2623
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0025 0.008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0049 0.0106
Echinococcus multilocularis neurogenic locus notch protein 0.003 0.0114 0.0138
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Brugia malayi Calcium binding EGF domain containing protein 0.003 0.0114 0.0114
Brugia malayi Calcium binding EGF domain containing protein 0.003 0.0114 0.0114
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0048 0.0258 0.0498
Echinococcus granulosus glycine receptor subunit alpha 1 0.0054 0.0303 0.0367
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0124 0.0124
Plasmodium vivax vivapain-3 0.0068 0.0404 0.5133
Echinococcus multilocularis neural cadherin 0.003 0.0114 0.0138
Brugia malayi Animal haem peroxidase family protein 0.0092 0.0588 0.0588
Trypanosoma brucei ISWI complex protein 0.0031 0.0121 0.0568
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0045 0.0045
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0096 0.021
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0266 0.0266
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.06 0.116
Brugia malayi Cation transporter family protein 0.0054 0.0303 0.0303
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0047 0.0103
Echinococcus multilocularis glutamate receptor 2 0.002 0.0041 0.0049
Leishmania major DNA polymerase kappa, putative 0.0021 0.0047 0.022
Schistosoma mansoni amine GPCR 0.0093 0.06 0.116
Brugia malayi hypothetical protein 0.0016 0.0013 0.0013
Mycobacterium tuberculosis Probable oxidoreductase 0.0277 0.2001 1
Brugia malayi G-protein coupled receptor 0.0093 0.06 0.06
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0036 0.016 0.078
Leishmania major cathepsin L-like protease 0.0114 0.0762 0.3577
Loa Loa (eye worm) ACC-1 protein 0.0054 0.0303 0.0303
Plasmodium falciparum serine repeat antigen 3 0.0036 0.016 0.1815
Onchocerca volvulus 0.0092 0.0588 0.3228
Toxoplasma gondii cathepsin CPL 0.0114 0.0762 0.4854
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.016 0.0617
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0124 0.0151
Brugia malayi hypothetical protein 0.0093 0.06 0.06
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0058 0.0333 0.0645
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0049 0.0227
Brugia malayi Papain family cysteine protease containing protein 0.0068 0.0404 0.0404
Loa Loa (eye worm) notch protein 0.003 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0036 0.016 0.016
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0124 0.0241
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Echinococcus multilocularis neurogenic locus protein delta 0.003 0.0114 0.0138
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0082 0.0518 0.2533
Echinococcus multilocularis glutamate receptor 2 0.0027 0.0095 0.0116
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.016 0.0617
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0013 0.0013
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0303 0.0303
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0231 0.0446
Echinococcus multilocularis cathepsin b 0.0612 0.4561 0.5523
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.016 0.0617
Brugia malayi Muscle positioning protein 4 0.003 0.0114 0.0114
Schistosoma mansoni cathepsin F (C01 family) 0.0114 0.0762 0.1472
Loa Loa (eye worm) matrixin family protein 0.0052 0.0289 0.0288
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0082 0.0518 0.2533
Onchocerca volvulus 0.0054 0.0303 0.1509
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0762 0.384
Schistosoma mansoni hypothetical protein 0.0033 0.0137 0.0266
Schistosoma mansoni glutamate receptor kainate 0.0027 0.0095 0.0185
Echinococcus multilocularis neurogenic locus notch protein 4 0.003 0.0114 0.0138
Loa Loa (eye worm) bromodomain containing protein 0.0035 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Echinococcus granulosus slit 2 protein 0.003 0.0114 0.0138
Echinococcus granulosus glycine receptor subunit alpha 1 0.0054 0.0303 0.0367
Echinococcus granulosus peptide allatostatin:somatostatin 0.0093 0.06 0.0726
Echinococcus granulosus tm gpcr rhodopsin 0.1095 0.8259 1
Brugia malayi Papain family cysteine protease containing protein 0.0068 0.0404 0.0404
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0058 0.0333 0.0645
Schistosoma mansoni biogenic amine receptor 0.0093 0.06 0.116
Loa Loa (eye worm) hypothetical protein 0.0049 0.0266 0.0265
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0045 0.0248
Onchocerca volvulus 0.0093 0.06 0.33
Onchocerca volvulus 0.0114 0.0762 0.4277
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0054 0.0303 0.0303
Loa Loa (eye worm) G-protein coupled receptor 0.0093 0.06 0.06
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0124 0.0241
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0036 0.016 0.031
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Onchocerca volvulus Neurogenic locus notch protein homolog 0.003 0.0114 0.0365
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0093 0.06 0.116
Echinococcus granulosus nAChR subunit 0.0029 0.0112 0.0135
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0025 0.008 0.0096
Onchocerca volvulus 0.0082 0.0518 0.2804
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0231 0.0446
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0189 0.0888
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0093 0.06 0.116
Loa Loa (eye worm) hypothetical protein 0.0025 0.008 0.0079
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0124 0.0124
Echinococcus granulosus 7TM GPCR rhodopsin 0.0093 0.06 0.0726
Leishmania major cathepsin L-like protease 0.0114 0.0762 0.3577
Brugia malayi GnHR receptor homolog 0.0093 0.06 0.06
Brugia malayi hypothetical protein 0.0092 0.0588 0.0588
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0025 0.008 0.0079
Leishmania major cathepsin L-like protease 0.0114 0.0762 0.3577
Schistosoma mansoni zinc finger protein 0.0031 0.0121 0.0234
Echinococcus granulosus importin subunit beta 1 0.0028 0.0101 0.0123
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0158 0.0305
Onchocerca volvulus Cathepsin L homolog 0.0036 0.016 0.0643
Echinococcus granulosus fmrfamide receptor 0.0093 0.06 0.0726
Brugia malayi Hemopexin family protein 0.0031 0.0123 0.0123
Schistosoma mansoni hypothetical protein 0.0442 0.3265 0.6313
Onchocerca volvulus 0.0114 0.0762 0.4277
Loa Loa (eye worm) hypothetical protein 0.0025 0.008 0.0079
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0036 0.016 0.031
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0054 0.0303 0.0367
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0093 0.06 0.06
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.06 0.0726
Echinococcus granulosus microtubule associated protein 2 0.0691 0.5172 0.6263
Trypanosoma brucei unspecified product 0.0021 0.0047 0.022
Brugia malayi cathepsin Z-like cysteine proteinase 0.0036 0.016 0.016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0114 0.0762 0.384
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Schistosoma mansoni ap endonuclease 0.0039 0.0189 0.0366
Schistosoma mansoni hypothetical protein 0.0093 0.06 0.116
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0093 0.06 0.0726
Echinococcus multilocularis survival motor neuron protein 1 0.0243 0.1742 0.2109
Echinococcus multilocularis serotonin receptor 0.0093 0.06 0.0726
Loa Loa (eye worm) hypothetical protein 0.0092 0.0588 0.0588
Echinococcus multilocularis zinc finger protein 0.0042 0.0212 0.0257
Schistosoma mansoni calpain-7 (C02 family) 0.0024 0.0072 0.0139
Echinococcus granulosus methyl CpG binding domain protein 2 0.0034 0.0148 0.0179
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0124 0.0151
Schistosoma mansoni alpha-1 adrenergic receptor 0.0093 0.06 0.116
Loa Loa (eye worm) neuropeptide F receptor 0.0093 0.06 0.06
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.06 0.116
Schistosoma mansoni slit 0.003 0.0114 0.022
Brugia malayi notch-like transmembrane receptor 0.003 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Giardia lamblia Cysteine protease 0.0036 0.016 0.078
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0074 0.0345
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0054 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0114 0.0762 0.0922
Brugia malayi ORL1-like opioid receptor 0.0093 0.06 0.06
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0189 0.0977
Onchocerca volvulus 0.0114 0.0762 0.4277
Plasmodium vivax serine-repeat antigen (SERA) 0.0036 0.016 0.1815
Entamoeba histolytica cysteine protease, putative 0.0068 0.0404 0.5302
Schistosoma mansoni nAChR subunit 0.0054 0.0303 0.0586
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0124 0.0124
Brugia malayi Papain family cysteine protease containing protein 0.0036 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0025 0.008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0093 0.06 0.0726
Brugia malayi nuclear receptor NHR-88 0.0031 0.0124 0.0124
Giardia lamblia Cathepsin L precursor 0.0036 0.016 0.078
Entamoeba histolytica cysteine proteinase, putative 0.0114 0.0762 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.06 0.116
Echinococcus multilocularis microtubule associated protein 2 0.0691 0.5172 0.6263
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Brugia malayi Cathepsin L-like precursor 0.0114 0.0762 0.0761
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0036 0.016 0.0617
Echinococcus granulosus dro:myosuppressin receptor 0.0093 0.06 0.0726
Loa Loa (eye worm) LGC-31 protein 0.0054 0.0303 0.0303
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0022 0.0054 0.0104
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0074 0.0964
Loa Loa (eye worm) cathepsin B 0.0214 0.1521 0.1521
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0093 0.06 0.0726
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0762 0.384
Toxoplasma gondii cathepsin B 0.0214 0.1521 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0035 0.0153 0.0185
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0124 0.0124
Echinococcus granulosus neuropeptide Y receptor 0.0093 0.06 0.0726
Onchocerca volvulus 0.0093 0.06 0.33
Loa Loa (eye worm) acetylcholine receptor protein 0.0025 0.008 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.022
Brugia malayi EGF-like domain containing protein 0.003 0.0114 0.0114
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0096 0.0942
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0047 0.0091
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0203 0.0444
Echinococcus granulosus neurogenic locus notch protein 0.003 0.0114 0.0138
Schistosoma mansoni hypothetical protein 0.0071 0.0427 0.0826
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0093 0.06 0.0726
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Echinococcus granulosus notch 0.003 0.0114 0.0138
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Onchocerca volvulus 0.0024 0.0074 0.0122
Brugia malayi EGF-like domain containing protein 0.003 0.0114 0.0114
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0203 0.0444
Echinococcus multilocularis calpain 0.0021 0.0049 0.0059
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0093 0.06 0.06
Plasmodium falciparum importin beta, putative 0.0028 0.0101 0.1015
Brugia malayi Serotonin receptor 0.0093 0.06 0.06
Brugia malayi Cathepsin L-like precursor 0.0114 0.0762 0.0761
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0137 0.0137
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0189 0.0858
Echinococcus multilocularis neuropeptide s receptor 0.0093 0.06 0.0726
Echinococcus granulosus cathepsin l cysteine peptidase 0.0114 0.0762 0.0922
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0074 0.0238
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0035 0.0153 0.0185
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0093 0.06 0.06
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0101 0.0382
Brugia malayi GCC2 and GCC3 family protein 0.003 0.0114 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0036 0.016 0.0617
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0093 0.06 0.0726
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Echinococcus granulosus snurportin 1 0.0298 0.2166 0.2623
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0054 0.0303 0.0367
Schistosoma mansoni cathepsin s 0.0032 0.0132 0.0255
Schistosoma mansoni hypothetical protein 0.0033 0.0137 0.0266
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0124 0.0241
Brugia malayi hypothetical protein 0.0093 0.06 0.06
Plasmodium vivax vivapain-2 0.0114 0.0762 1
Trypanosoma cruzi ISWI complex protein 0.0031 0.0121 0.0265
Echinococcus multilocularis cysteine protease 0.0114 0.0762 0.0922
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0029 0.0112 0.0111
Onchocerca volvulus 0.0093 0.06 0.33
Brugia malayi hypothetical protein 0.0025 0.008 0.0079
Leishmania major DNA polymerase eta, putative 0.0021 0.0047 0.022
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0036 0.016 0.031
Echinococcus granulosus neuropeptide Y receptor 0.0093 0.06 0.0726
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0124 0.0124
Giardia lamblia Cathepsin L precursor 0.0036 0.016 0.078
Loa Loa (eye worm) hypothetical protein 0.0032 0.0132 0.0131
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0774 0.0773
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0774 0.0773
Echinococcus granulosus fetal alzheimer antigen falz 0.0048 0.0258 0.0312
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0054 0.0303 0.0367
Echinococcus granulosus G protein coupled receptor 139 0.0093 0.06 0.0726
Onchocerca volvulus 0.0036 0.016 0.0643
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Giardia lamblia Cathepsin B precursor 0.0214 0.1521 1
Loa Loa (eye worm) hypothetical protein 0.0103 0.0677 0.0676
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0103 0.0677 0.0676
Brugia malayi Cathepsin L-like precursor 0.0114 0.0762 0.0761
Echinococcus granulosus g-protein coupled receptor 0.0093 0.06 0.0726
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0293 0.2128 0.4666
Onchocerca volvulus 0.0054 0.0303 0.1509
Loa Loa (eye worm) hypothetical protein 0.0092 0.0588 0.0588
Echinococcus multilocularis cathepsin b 0.0612 0.4561 0.5523
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0045 0.0098
Onchocerca volvulus 0.0093 0.06 0.33
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0047 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0404 0.1924
Schistosoma mansoni microtubule-associated protein tau 0.0691 0.5172 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0028 0.0101 0.0101
Echinococcus granulosus zinc finger protein 0.0042 0.0212 0.0257
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0189 0.0414
Echinococcus multilocularis cathepsin L 0.0036 0.016 0.0194
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0074 0.0275
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0074 0.0238
Toxoplasma gondii hypothetical protein 0.0047 0.0249 0.1384
Brugia malayi neuropeptide F receptor 0.0093 0.06 0.06
Leishmania major hypothetical protein, conserved 0.0027 0.0096 0.045
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.0148 0.0286
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0074 0.0345
Schistosoma mansoni nAChR subunit 0.0025 0.008 0.0154
Loa Loa (eye worm) hypothetical protein 0.0025 0.008 0.0079
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Schistosoma mansoni neurotransmitter gated ion channel 0.0029 0.0112 0.0216
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0114 0.0762 0.384
Schistosoma mansoni hypothetical protein 0.0031 0.0123 0.0237
Loa Loa (eye worm) G-protein coupled receptor 0.0093 0.06 0.06
Brugia malayi Animal haem peroxidase family protein 0.0092 0.0588 0.0588
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0049 0.0106
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0093 0.06 0.116
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0114 0.0762 0.384
Brugia malayi hypothetical protein 0.0027 0.0096 0.0096
Schistosoma mansoni hypothetical protein 0.0331 0.2416 0.467
Loa Loa (eye worm) hypothetical protein 0.0025 0.008 0.0079
Schistosoma mansoni notch 0.003 0.0114 0.022
Echinococcus multilocularis calpain 5 0.0021 0.0049 0.0059
Brugia malayi Pax transcription factor protein 2 0.0238 0.1709 0.1709
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0054 0.0303 0.0303
Schistosoma mansoni notch 0.003 0.0114 0.022
Echinococcus granulosus neural cadherin 0.003 0.0114 0.0138
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0045 0.0098
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Brugia malayi Matrixin family protein 0.0022 0.0054 0.0053
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0124 0.0151
Schistosoma mansoni coup transcription factor 0.0031 0.0124 0.0241
Loa Loa (eye worm) hypothetical protein 0.0025 0.008 0.0079
Trypanosoma cruzi cysteine peptidase, putative 0.0114 0.0762 0.1669
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0036 0.016 0.1815
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.016 0.0617
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0058 0.0333 0.0404
Loa Loa (eye worm) hypothetical protein 0.0082 0.0518 0.0517
Onchocerca volvulus 0.0093 0.06 0.33
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0093 0.06 0.33
Toxoplasma gondii cathepsin CPC1 0.0036 0.016 0.078
Echinococcus multilocularis glycine receptor subunit beta 0.0054 0.0303 0.0367
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0036 0.016 0.1815
Brugia malayi Cathepsin L-like precursor 0.0082 0.0518 0.0517
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0093 0.06 0.06
Schistosoma mansoni glutamate receptor kainate 0.0027 0.0095 0.0185
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.003 0.0114 0.0114
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.06 0.0726
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0074 0.0238
Plasmodium vivax unspecified product 0.0032 0.0132 0.1429
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0047 0.022
Trypanosoma cruzi cruzipain precursor, putative 0.0032 0.0132 0.0288
Loa Loa (eye worm) Notch2 0.003 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Echinococcus multilocularis cpg binding protein 0.0066 0.0395 0.0479
Echinococcus granulosus neuropeptide FF receptor 2 0.0093 0.06 0.0726
Loa Loa (eye worm) hypothetical protein 0.0036 0.016 0.016
Onchocerca volvulus Peroxidase homolog 0.0092 0.0588 0.3228
Echinococcus granulosus g protein coupled receptor 0.0093 0.06 0.0726
Giardia lamblia Cathepsin B precursor 0.0036 0.016 0.078
Echinococcus granulosus protein jagged 2 0.003 0.0114 0.0138
Echinococcus granulosus neuropeptide receptor 0.0093 0.06 0.0726
Onchocerca volvulus 0.0049 0.0266 0.1283
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0054 0.0303 0.0367
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0061 0.0133
Loa Loa (eye worm) hypothetical protein 0.0024 0.0074 0.0073
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Plasmodium vivax serine-repeat antigen (SERA) 0.0036 0.016 0.1815
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0787 0.5904 0.7148
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0054 0.0303 0.0367
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0074 0.0238
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0036 0.016 0.1815
Entamoeba histolytica hypothetical protein 0.0035 0.0158 0.2066
Echinococcus multilocularis dro:myosuppressin receptor 0.0093 0.06 0.0726
Onchocerca volvulus 0.003 0.0114 0.0365
Echinococcus granulosus calpain A 0.0021 0.0049 0.0059
Loa Loa (eye worm) hypothetical protein 0.0025 0.008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Entamoeba histolytica cysteine protease, putative 0.0068 0.0404 0.5302
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0036 0.016 0.1815
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0061 0.0086
Brugia malayi glutaminase DH11.1 0.0265 0.1911 0.1911
Trypanosoma cruzi cruzipain precursor, putative 0.0114 0.0762 0.1669
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Schistosoma mansoni glutamate receptor AMPA 0.0027 0.0095 0.0185
Entamoeba histolytica cysteine proteinase, putative 0.0068 0.0404 0.5302
Loa Loa (eye worm) hypothetical protein 0.0033 0.0137 0.0137
Trypanosoma cruzi cysteine proteinase, putative 0.0068 0.0404 0.0885
Giardia lamblia Cathepsin L-like protease 0.0036 0.016 0.078
Echinococcus multilocularis GPCR, family 2 0.0033 0.0137 0.0166
Trypanosoma brucei cysteine peptidase C (CPC) 0.0214 0.1521 0.7147
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0054 0.0303 0.0303
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0231 0.0279
Trypanosoma cruzi cysteine proteinase, putative 0.0068 0.0404 0.0885
Mycobacterium tuberculosis Conserved hypothetical protein 0.0154 0.1068 0.5292
Loa Loa (eye worm) hypothetical protein 0.0092 0.0588 0.0588
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0028 0.0034
Plasmodium falciparum serine repeat antigen 8 0.0036 0.016 0.1815
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Toxoplasma gondii exonuclease III APE 0.0039 0.0189 0.0977
Loa Loa (eye worm) hypothetical protein 0.0031 0.0124 0.0124
Echinococcus multilocularis cysteine protease 0.0114 0.0762 0.0922
Brugia malayi calpain 7 0.0021 0.0049 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.022
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0054 0.0303 0.0586
Schistosoma mansoni hypothetical protein 0.003 0.0114 0.022
Loa Loa (eye worm) hypothetical protein 0.0092 0.0588 0.0588
Mycobacterium ulcerans short chain dehydrogenase 0.0277 0.2001 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0404 0.1897
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0124 0.0428
Brugia malayi cathepsin Z-like cysteine proteinase 0.0036 0.016 0.016
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0074 0.0964
Brugia malayi EGF-like domain containing protein 0.003 0.0114 0.0114
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0231 0.0279
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0124 0.0241
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0047 0.0142
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0948 0.4454
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0061 0.0086
Loa Loa (eye worm) PHD-finger family protein 0.0041 0.0203 0.0202
Onchocerca volvulus 0.0025 0.008 0.0157
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.022
Echinococcus granulosus glutamate NMDA receptor subunit 0.0136 0.0929 0.1125
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0047 0.0057
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0093 0.06 0.116
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0093 0.06 0.0726
Brugia malayi Cathepsin L-like precursor 0.0114 0.0762 0.0761
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0054 0.0303 0.0303
Onchocerca volvulus 0.0093 0.06 0.33
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0029 0.0112 0.0216
Onchocerca volvulus 0.003 0.0114 0.0365
Echinococcus multilocularis calpain 7 (C02 family) 0.0021 0.0049 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0124 0.0124
Entamoeba histolytica cysteine protease, putative 0.0068 0.0404 0.5302
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0404 0.1924
Onchocerca volvulus 0.0093 0.06 0.33
Onchocerca volvulus 0.0029 0.0112 0.0351
Brugia malayi cathepsin F-like cysteine proteinase 0.0032 0.0132 0.0131
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0093 0.06 0.0726
Brugia malayi hypothetical protein 0.0093 0.06 0.06
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0762 0.384
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0101 0.0123
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0101 0.0474
Onchocerca volvulus 0.0092 0.0588 0.3228
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0049 0.0106
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0054 0.0303 0.0303
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0093 0.06 0.0726
Schistosoma mansoni hypothetical protein 0.003 0.0114 0.022
Echinococcus granulosus cathepsin L cysteine proteinase 0.0114 0.0762 0.0922
Mycobacterium ulcerans hydrolase 0.0026 0.009 0.0319
Brugia malayi Papain family cysteine protease containing protein 0.0036 0.016 0.016
Loa Loa (eye worm) ctsf protein 0.0114 0.0762 0.0761
Entamoeba histolytica cysteine protease, putative 0.0036 0.016 0.2099
Echinococcus granulosus neuropeptide s receptor 0.0093 0.06 0.0726
Schistosoma mansoni calpain C (C02 family) 0.0021 0.0049 0.0094
Schistosoma mansoni nAChR subunit 0.0025 0.008 0.0154
Giardia lamblia Cathepsin B precursor 0.0036 0.016 0.078
Trypanosoma cruzi ISWI complex protein 0.0031 0.0121 0.0265
Loa Loa (eye worm) hypothetical protein 0.0092 0.0588 0.0588
Schistosoma mansoni ATP-binding cassette transporter 0.0027 0.0095 0.0185
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.016 0.0617
Schistosoma mansoni neurotransmitter gated ion channel 0.0025 0.008 0.0154
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0054 0.0303 0.0586
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0025 0.008 0.0079
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0025 0.008 0.0096
Loa Loa (eye worm) ACC-1 protein 0.0054 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.022
Onchocerca volvulus Chorion peroxidase homolog 0.0092 0.0588 0.3228
Onchocerca volvulus 0.0093 0.06 0.33
Schistosoma mansoni biogenic amine (5HT) receptor 0.0093 0.06 0.116
Plasmodium vivax importin-beta 2, putative 0.0028 0.0101 0.1015
Leishmania major cathepsin L-like protease 0.0114 0.0762 0.3577
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0079 0.049 0.0594
Echinococcus granulosus cathepsin l1 0.0114 0.0762 0.0922
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0093 0.06 0.0726
Echinococcus multilocularis dna polymerase eta 0.0021 0.0047 0.0057
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0036 0.016 0.031
Echinococcus granulosus cathepsin b 0.0612 0.4561 0.5523
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0047 0.022
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Schistosoma mansoni glutamate receptor NMDA 0.0035 0.0153 0.0296
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0068 0.0404 0.0781
Entamoeba histolytica cysteine protease, putative 0.0036 0.016 0.2099
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0189 0.0773
Entamoeba histolytica hypothetical protein 0.0035 0.0158 0.2066
Echinococcus multilocularis G protein coupled receptor 139 0.0093 0.06 0.0726
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0189 0.0888
Echinococcus multilocularis neurogenic locus notch protein 0.003 0.0114 0.0138
Loa Loa (eye worm) hypothetical protein 0.0092 0.0588 0.0588
Loa Loa (eye worm) hypothetical protein 0.0036 0.016 0.016
Leishmania major importin beta-1 subunit, putative 0.0023 0.0061 0.0285
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0139 0.0948 0.4454
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0025 0.008 0.0079
Schistosoma mansoni neuropeptide F-like receptor 0.0093 0.06 0.116
Echinococcus granulosus delta-like protein 1 0.003 0.0114 0.0138
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0048 0.0258 0.0312
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0036 0.016 0.031
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0612 0.4561 0.8819
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0114 0.0762 1
Brugia malayi G protein-coupled receptor 0.0093 0.06 0.06
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0049 0.0227
Loa Loa (eye worm) hypothetical protein 0.0243 0.1742 0.1741
Entamoeba histolytica hypothetical protein 0.0029 0.0112 0.1463
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0036 0.016 0.078
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.022
Loa Loa (eye worm) glutamate receptor 2 0.0027 0.0095 0.0095
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0214 0.1521 0.7147
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0054 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Loa Loa (eye worm) hypothetical protein 0.0025 0.008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0092 0.0588 0.0588
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0124 0.0124
Onchocerca volvulus 0.0054 0.0303 0.1509
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0114 0.0762 0.3577
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0124 0.0124
Brugia malayi hypothetical protein 0.0093 0.06 0.06
Loa Loa (eye worm) hypothetical protein 0.0141 0.0967 0.0966
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0404 0.1897
Plasmodium falciparum serine repeat antigen 5 0.0036 0.016 0.1815
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0047 0.0103
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0013
Trypanosoma cruzi major cysteine proteinase, putative 0.0036 0.016 0.035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0762 0.384
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0036 0.016 0.031
Schistosoma mansoni neuropeptide receptor 0.0093 0.06 0.116
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0049 0.0106
Echinococcus granulosus cathepsin b 0.0612 0.4561 0.5523
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0124 0.0241
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0035 0.0153 0.0185
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0035 0.0153 0.0185
Schistosoma mansoni neuropeptide F-like receptor 0.0093 0.06 0.116
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0093 0.06 0.0726
Entamoeba histolytica cysteine protease, putative 0.0068 0.0404 0.5302
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0436 0.0528
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0612 0.4561 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0047 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0114 0.0762 0.3577
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0101 0.0474
Echinococcus granulosus hypothetical protein 0.0093 0.06 0.0726
Echinococcus multilocularis glutamate receptor 2 0.0035 0.0153 0.0185
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0762 0.384
Loa Loa (eye worm) hypothetical protein 0.0018 0.0027 0.0026
Giardia lamblia Cathepsin B precursor 0.0214 0.1521 1
Brugia malayi fibroinase precursor 0.0036 0.016 0.016
Entamoeba histolytica cysteine protease, putative 0.0068 0.0404 0.5302
Echinococcus granulosus cysteine protease 0.0068 0.0404 0.0489
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0036 0.016 0.016
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0029 0.0112 0.0216
Echinococcus granulosus glycine receptor subunit beta 0.0054 0.0303 0.0367
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0093 0.06 0.116
Onchocerca volvulus 0.0114 0.0762 0.4277
Schistosoma mansoni hypothetical protein 0.0033 0.0137 0.0266
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0231 0.0231
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0158 0.0305
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0018 0.0027 0.0026
Schistosoma mansoni cathepsin B (C01 family) 0.0036 0.016 0.031
Entamoeba histolytica cysteine protease, putative 0.0068 0.0404 0.5302
Onchocerca volvulus Peroxidase homolog 0.0092 0.0588 0.3228
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0054 0.0303 0.0367
Echinococcus multilocularis calpain A 0.0058 0.0333 0.0404
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0054 0.0303 0.0586
Brugia malayi hypothetical protein 0.0093 0.06 0.06
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0027 0.0038
Brugia malayi Calcium binding EGF domain containing protein 0.003 0.0114 0.0114
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0047 0.0047
Schistosoma mansoni cpg binding protein 0.0066 0.0395 0.0764
Loa Loa (eye worm) hypothetical protein 0.0612 0.4561 0.4561
Schistosoma mansoni peroxidasin 0.0092 0.0588 0.1137
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0034 0.0148 0.0179
Onchocerca volvulus 0.0093 0.06 0.33
Onchocerca volvulus Peroxidasin homolog 0.0092 0.0588 0.3228
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0036 0.016 0.031
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.008 0.0079
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0036 0.016 0.031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0114 0.0762 0.3577
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Brugia malayi excitatory GABA receptor EXP-1A 0.0054 0.0303 0.0303
Schistosoma mansoni nAChR subunit 0.0054 0.0303 0.0586
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0054 0.0303 0.0303
Echinococcus granulosus neuropeptide receptor A26 0.0093 0.06 0.0726
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0231 0.0231
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.0148 0.0286
Brugia malayi Cathepsin L-like precursor 0.0082 0.0518 0.0517
Brugia malayi RNA, U transporter 1 0.0079 0.0495 0.0494
Schistosoma mansoni nAChR subunit 0.0054 0.0303 0.0586
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0036 0.016 0.1815
Schistosoma mansoni nAChR subunit 0.0054 0.0303 0.0586
Loa Loa (eye worm) fibroinase 0.0114 0.0762 0.0761
Onchocerca volvulus 0.0031 0.0123 0.0418
Loa Loa (eye worm) matrixin family protein 0.0048 0.0255 0.0255
Entamoeba histolytica cysteine proteinase, putative 0.0082 0.0518 0.6797
Loa Loa (eye worm) hypothetical protein 0.0077 0.0473 0.0473
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0047 0.0104
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0114 0.0762 0.384
Onchocerca volvulus 0.0054 0.0303 0.1509
Brugia malayi Papain family cysteine protease containing protein 0.0114 0.0762 0.0761
Mycobacterium ulcerans glutaminase 0.0265 0.1911 0.9545
Loa Loa (eye worm) hypothetical protein 0.0081 0.0509 0.0509
Entamoeba histolytica cysteine proteinase 1, putative 0.0068 0.0404 0.5302
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0114 0.0762 0.3577
Echinococcus granulosus cathepsin L 0.0036 0.016 0.0194
Brugia malayi cathepsin L-like precursor 0.0082 0.0518 0.0517
Brugia malayi hypothetical protein 0.0093 0.06 0.06
Toxoplasma gondii preprocathepsin c precursor, putative 0.0036 0.016 0.078
Loa Loa (eye worm) hypothetical protein 0.0025 0.008 0.0079
Echinococcus granulosus somatostatin receptor 0.0093 0.06 0.0726
Mycobacterium ulcerans hypothetical protein 0.0024 0.0074 0.0238
Schistosoma mansoni notch 0.003 0.0114 0.022
Onchocerca volvulus 0.0025 0.008 0.0157
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.003 0.0114 0.022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.016 0.0617
Leishmania major cysteine peptidase A (CPA) 0.0114 0.0762 0.3577
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.06 0.0726
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1095 0.8259 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.016 0.016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.016 0.0617
Plasmodium vivax unspecified product 0.0036 0.016 0.1815
Giardia lamblia Cathepsin L-like protease 0.0036 0.016 0.078
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0036 0.016 0.016
Plasmodium falciparum serine repeat antigen 9 0.0036 0.016 0.1815
Onchocerca volvulus 0.0093 0.06 0.33
Brugia malayi hypothetical protein 0.0093 0.06 0.06
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0762 0.384
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0093 0.06 0.116
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Echinococcus multilocularis protein jagged 1 0.003 0.0114 0.0138
Echinococcus granulosus GPCR family 2 0.0033 0.0137 0.0166
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0036 0.016 0.0617
Brugia malayi Matrixin family protein 0.0052 0.0289 0.0288
Loa Loa (eye worm) hypothetical protein 0.0092 0.0588 0.0588
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Schistosoma mansoni laminin gamma-3 chain 0.003 0.0114 0.022
Entamoeba histolytica hypothetical protein 0.0035 0.0158 0.2066
Schistosoma mansoni calpain (C02 family) 0.0021 0.0049 0.0094
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0124 0.0241
Echinococcus multilocularis neuropeptide FF receptor 2 0.0093 0.06 0.0726
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0047 0.0616
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0049 0.0227
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.016 0.0617
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0074 0.0073
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Giardia lamblia Cathepsin L precursor 0.0036 0.016 0.078
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0036 0.016 0.0617
Mycobacterium leprae PROBABLE HYDROLASE 0.0026 0.009 1
Schistosoma mansoni cathepsin F (C01 family) 0.0114 0.0762 0.1472
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0093 0.06 0.116
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0114 0.0762 1
Brugia malayi Peroxidasin 0.0092 0.0588 0.0588
Trypanosoma cruzi cysteine peptidase, putative 0.0114 0.0762 0.1669
Schistosoma mansoni glutaminase 0.0265 0.1911 0.3695
Brugia malayi Cation transporter family protein 0.0054 0.0303 0.0303
Brugia malayi hypothetical protein 0.0018 0.0022 0.0022
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0114 0.0762 0.384
Echinococcus multilocularis fibropellin Ia 0.003 0.0114 0.0138
Brugia malayi Papain family cysteine protease containing protein 0.0036 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0092 0.0588 0.0588
Entamoeba histolytica cysteine proteinase, putative 0.0114 0.0762 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0074 0.0964
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0047 0.0047
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0189 0.2481
Onchocerca volvulus Dual oxidase homolog 0.0092 0.0588 0.3228
Loa Loa (eye worm) hypothetical protein 0.0036 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0022 0.0054 0.0053
Echinococcus multilocularis allatostatin A receptor 0.0093 0.06 0.0726
Echinococcus multilocularis sex peptide receptor 0.0093 0.06 0.0726
Loa Loa (eye worm) hypothetical protein 0.0082 0.0518 0.0517
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0093 0.06 0.116
Brugia malayi putative neuropeptide receptor 0.0093 0.06 0.06
Onchocerca volvulus 0.0093 0.06 0.33
Loa Loa (eye worm) hypothetical protein 0.0031 0.0124 0.0124
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0021 0.0049 0.0106
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0114 0.0762 0.384
Onchocerca volvulus 0.0031 0.0124 0.0428
Entamoeba histolytica cysteine protease, putative 0.0068 0.0404 0.5302
Loa Loa (eye worm) hypothetical protein 0.0035 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0114 0.0762 0.0761
Schistosoma mansoni hypothetical protein 0.0049 0.0266 0.0514
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0124 0.0151
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0029 0.0112 0.0111
Loa Loa (eye worm) blistered cuticle protein 3 0.0092 0.0588 0.0588
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0093 0.06 0.06
Schistosoma mansoni opsin-like receptor 0.0093 0.06 0.116
Loa Loa (eye worm) calpain 0.0021 0.0049 0.0048
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0093 0.06 0.0726
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.06 0.116
Echinococcus multilocularis nAChR subunit 0.0054 0.0303 0.0367
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0031 0.0124 0.0124
Echinococcus granulosus nmda type glutamate receptor 0.0033 0.0144 0.0174
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0158 0.0191
Loa Loa (eye worm) hypothetical protein 0.0018 0.0027 0.0026
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0074 0.0238
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0189 0.0773
Giardia lamblia Cathepsin L precursor 0.0036 0.016 0.078
Giardia lamblia Cysteine protease 0.0036 0.016 0.078
Brugia malayi hypothetical protein 0.0025 0.008 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0762 0.384
Trypanosoma cruzi cysteine peptidase, putative 0.0032 0.0132 0.0288
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0049 0.0106
Schistosoma mansoni hypothetical protein 0.0033 0.0137 0.0266
Entamoeba histolytica cysteine proteinase, putative 0.0068 0.0404 0.5302
Brugia malayi Matrixin family protein 0.0022 0.0054 0.0053
Echinococcus granulosus glycine receptor subunit alpha 1 0.0054 0.0303 0.0367
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0124 0.0124
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0189 0.5
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0068 0.0404 0.0885
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0068 0.0404 0.0781
Echinococcus granulosus neurogenic locus protein delta 0.003 0.0114 0.0138
Brugia malayi Animal haem peroxidase family protein 0.0092 0.0588 0.0588
Loa Loa (eye worm) hypothetical protein 0.0041 0.0202 0.0201
Schistosoma mansoni adenoreceptor 0.0093 0.06 0.116
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0124 0.0151
Plasmodium vivax vivapain-2 0.0114 0.0762 1
Entamoeba histolytica cysteine protease, putative 0.0114 0.0762 1
Schistosoma mansoni hypothetical protein 0.0041 0.0203 0.0392
Onchocerca volvulus 0.0093 0.06 0.33
Brugia malayi putative neuropeptide receptor NPR1 0.0093 0.06 0.06
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0298 0.2166 0.2166
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0612 0.4561 0.8819
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0082 0.0518 0.1134
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0124 0.0428
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0036 0.016 0.016
Leishmania major cathepsin L-like protease 0.0114 0.0762 0.3577
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0114 0.0762 0.0761
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0114 0.0762 0.3577
Schistosoma mansoni opsin-like receptor 0.0093 0.06 0.116
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0124 0.0124
Schistosoma mansoni amine GPCR 0.0093 0.06 0.116
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0035 0.0153 0.0185
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0049 0.0227
Echinococcus granulosus neurogenic locus notch protein 0.003 0.0114 0.0138
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0189 0.0414
Brugia malayi N-terminal motif family protein 0.0195 0.1378 0.1378
Onchocerca volvulus Slit protein homolog 0.003 0.0114 0.0365
Onchocerca volvulus 0.0148 0.1021 0.5843
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0114 0.0762 0.3577
Loa Loa (eye worm) glutaminase 2 0.0265 0.1911 0.1911
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0231 0.0446
Brugia malayi ecdysteroid receptor 0.0031 0.0124 0.0124
Brugia malayi Cation transporter family protein 0.0054 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0024 0.0074 0.0073
Giardia lamblia Cathepsin L precursor 0.0036 0.016 0.078
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0093 0.06 0.0726
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0093 0.06 0.0726
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Schistosoma mansoni opsin-like receptor 0.0093 0.06 0.116
Echinococcus granulosus cpg binding protein 0.0066 0.0395 0.0479
Schistosoma mansoni cathepsin C 0.0036 0.016 0.031
Mycobacterium ulcerans hypothetical protein 0.0154 0.1068 0.5274
Echinococcus granulosus biogenic amine 5HT receptor 0.0093 0.06 0.0726
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0045 0.0054
Loa Loa (eye worm) neuropeptide F receptor 0.0093 0.06 0.06
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0055 0.0055
Brugia malayi Importin beta-1 subunit 0.0028 0.0101 0.0101
Echinococcus multilocularis geminin 0.0331 0.2416 0.2925
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0124 0.0241
Giardia lamblia Encystation-specific protease 0.0036 0.016 0.078
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.06 0.116
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0124 0.0241
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0045 0.0054
Schistosoma mansoni glutamate receptor AMPA 0.0027 0.0095 0.0185
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0114 0.0762 0.384
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0054 0.0303 0.0367
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0025 0.008 0.0096
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0203 0.0952
Echinococcus granulosus glycine receptor subunit beta 0.0054 0.0303 0.0367
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0404 0.0885
Echinococcus multilocularis g protein coupled receptor 0.0093 0.06 0.0726
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0049 0.0106
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0093 0.06 0.116
Schistosoma mansoni ran 0.0021 0.0045 0.0087
Schistosoma mansoni neuropeptide receptor 0.0093 0.06 0.116
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0762 0.384
Plasmodium falciparum serine repeat antigen 4 0.0036 0.016 0.1815
Loa Loa (eye worm) hypothetical protein 0.1323 1 1
Schistosoma mansoni amine GPCR 0.0093 0.06 0.116
Loa Loa (eye worm) hypothetical protein 0.0032 0.0132 0.0131
Brugia malayi hypothetical protein 0.0025 0.008 0.0079
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0124 0.0124
Schistosoma mansoni nAChR subunit 0.0054 0.0303 0.0586
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Plasmodium vivax calpain, putative 0.0021 0.0049 0.0298
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0054 0.0303 0.0367
Onchocerca volvulus 0.0035 0.0153 0.0603
Schistosoma mansoni zinc finger protein 0.0042 0.0212 0.041
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0033 0.0144 0.0174
Schistosoma mansoni hypothetical protein 0.0093 0.06 0.116
Loa Loa (eye worm) hypothetical protein 0.0089 0.0564 0.0564
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0137 0.0166
Loa Loa (eye worm) hypothetical protein 0.0022 0.0054 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0036 0.016 0.0617
Leishmania major mitochondrial DNA polymerase beta 0.0293 0.2128 1
Brugia malayi cathepsin L-like cysteine proteinase 0.0036 0.016 0.016
Echinococcus granulosus cathepsin L cysteine protease 0.0068 0.0404 0.0489
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0049 0.0227
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0045 0.021
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0074 0.0345
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0114 0.0762 0.384
Brugia malayi CXXC zinc finger family protein 0.0059 0.034 0.034
Loa Loa (eye worm) hypothetical protein 0.0021 0.0047 0.0047
Trypanosoma cruzi cysteine peptidase, putative 0.0114 0.0762 0.1669
Echinococcus granulosus cathepsin l1 0.0082 0.0518 0.0627
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0124 0.0151
Loa Loa (eye worm) glutamate receptor 1 0.0027 0.0095 0.0095
Leishmania major GTP-binding protein, putative 0.0021 0.0045 0.021
Echinococcus granulosus serotonin receptor 0.0093 0.06 0.0726
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0137 0.0166
Echinococcus granulosus orexin receptor type 2 0.0093 0.06 0.0726
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0068 0.0404 0.0781
Echinococcus multilocularis fmrfamide receptor 0.0093 0.06 0.0726
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0047 0.0103
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0093 0.06 0.0726
Onchocerca volvulus Cathepsin L homolog 0.0114 0.0762 0.4277
Schistosoma mansoni notch 0.003 0.0114 0.022
Schistosoma mansoni amine GPCR 0.0093 0.06 0.116
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0158 0.0191
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0029 0.0112 0.0111
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0124 0.0124
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0114 0.0762 0.0922
Loa Loa (eye worm) animal heme peroxidase 0.0092 0.0588 0.0588
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0124 0.0124
Echinococcus multilocularis cathepsin L 0.0068 0.0404 0.0489
Schistosoma mansoni hypothetical protein 0.0093 0.06 0.116
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0054 0.0303 0.0367
Schistosoma mansoni glutamate receptor NMDA 0.0136 0.0929 0.1796
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0028 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.06 0.0726
Loa Loa (eye worm) TYRA-2 protein 0.0093 0.06 0.06
Echinococcus granulosus calpain A 0.0058 0.0333 0.0404
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.06 0.0726
Brugia malayi follicle stimulating hormone receptor 0.0324 0.2361 0.2361
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Brugia malayi Animal haem peroxidase family protein 0.0092 0.0588 0.0588
Loa Loa (eye worm) hypothetical protein 0.0056 0.0314 0.0314
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0029 0.0112 0.0111
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0026 0.009 0.0356
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0189 1
Loa Loa (eye worm) hypothetical protein 0.0195 0.1378 0.1378
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.008 0.0079
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0436 0.0528
Schistosoma mansoni neuropeptide f receptor 76f 0.0093 0.06 0.116
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Loa Loa (eye worm) hypothetical protein 0.0025 0.008 0.0079
Schistosoma mansoni growth hormone secretagogue receptor 0.0093 0.06 0.116
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.06 0.0726
Echinococcus granulosus tachykinin peptides receptor 99D 0.0677 0.5059 0.6125
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0054 0.0303 0.0367
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0124 0.0124
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0114 0.0762 0.0761
Echinococcus granulosus nAChR subunit 0.0054 0.0303 0.0367
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0047 0.0103
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0137 0.0166
Onchocerca volvulus 0.0054 0.0303 0.1509
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.016 0.0617
Giardia lamblia Cathepsin B precursor 0.0036 0.016 0.078
Loa Loa (eye worm) hypothetical protein 0.0022 0.0054 0.0053
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Echinococcus multilocularis g-protein coupled receptor 0.0093 0.06 0.0726
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0036 0.016 0.0617
Loa Loa (eye worm) hypothetical protein 0.0092 0.0588 0.0588
Plasmodium falciparum cysteine proteinase falcipain 3 0.0114 0.0762 1
Echinococcus multilocularis protein jagged 1 0.003 0.0114 0.0138
Brugia malayi hypothetical protein 0.0148 0.1021 0.1021
Plasmodium falciparum serine repeat antigen 2 0.0036 0.016 0.1815
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0035 0.0153 0.0185
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0036 0.016 0.078
Schistosoma mansoni hypothetical protein 0.0298 0.2166 0.4188
Schistosoma mansoni biogenic amine receptor 0.0093 0.06 0.116
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0025 0.008 0.0096
Loa Loa (eye worm) hypothetical protein 0.0092 0.0588 0.0588
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0124 0.0241
Brugia malayi Cathepsin L-like cysteine proteinase 0.0082 0.0518 0.0517
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0054 0.0303 0.0303
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0028 0.0028
Brugia malayi cathepsin F-like cysteine proteinase 0.0036 0.016 0.016
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0054 0.0303 0.0367
Loa Loa (eye worm) pax transcription factor protein 2 0.0238 0.1709 0.1709
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0054 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0036 0.016 0.016
Entamoeba histolytica cysteine protease, putative 0.0036 0.016 0.2099
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0158 0.0305
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.008 0.0079
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0124 0.0151
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0036 0.016 0.0617
Schistosoma mansoni hypothetical protein 0.0031 0.0121 0.0234
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0762 0.384
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0047 0.022
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0032 0.0132 0.0131
Schistosoma mansoni myosin xvIII 0.0093 0.06 0.116
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.06 0.0726
Schistosoma mansoni septate junction protein 0.003 0.0114 0.022
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0047 0.0057
Echinococcus multilocularis peroxidasin 0.0092 0.0588 0.0712
Schistosoma mansoni cell polarity protein 0.003 0.0114 0.022
Echinococcus granulosus geminin 0.0331 0.2416 0.2925
Schistosoma mansoni ap endonuclease 0.0039 0.0189 0.0366
Entamoeba histolytica cysteine protease, putative 0.0068 0.0404 0.5302
Giardia lamblia Hypothetical protein 0.0036 0.016 0.078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0762 0.384
Onchocerca volvulus Peroxidasin homolog 0.0092 0.0588 0.3228
Brugia malayi calpain family protein 1 0.0056 0.0314 0.0314
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0293 0.2128 0.4666
Schistosoma mansoni histamine h1 receptor 0.0093 0.06 0.116
Schistosoma mansoni amine GPCR 0.0093 0.06 0.116
Entamoeba histolytica cysteine protease, putative 0.0036 0.016 0.2099
Brugia malayi Animal haem peroxidase family protein 0.0092 0.0588 0.0588
Brugia malayi Bromodomain containing protein 0.0076 0.0472 0.0472
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0047 0.0103
Echinococcus granulosus dna polymerase eta 0.0021 0.0047 0.0057
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0019 0.0032 0.0025
Loa Loa (eye worm) hypothetical protein 0.0092 0.0588 0.0588
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0096 0.0346
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0093 0.06 0.06
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0096 0.045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.06 0.116
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0762 0.384
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0047 0.022
Brugia malayi EGF-like domain containing protein 0.003 0.0114 0.0114
Brugia malayi hypothetical protein 0.0035 0.0158 0.0157
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Schistosoma mansoni ran 0.0021 0.0045 0.0087
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0124 0.0151
Schistosoma mansoni peroxidasin 0.0092 0.0588 0.1137
Loa Loa (eye worm) hypothetical protein 0.0351 0.2573 0.2573
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0612 0.4561 0.8819
Entamoeba histolytica cysteine protease, putative 0.0036 0.016 0.2099
Brugia malayi AKH receptor 0.0093 0.06 0.06
Brugia malayi Cathepsin L-like precursor 0.0114 0.0762 0.0761
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0019 0.0032 0.0063
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0035 0.0153 0.0185
Brugia malayi MH2 domain containing protein 0.0116 0.0774 0.0773
Brugia malayi nuclear hormone receptor 0.0031 0.0124 0.0124
Brugia malayi larval opioid receptor 0.0093 0.06 0.06
Echinococcus multilocularis orexin receptor type 2 0.0093 0.06 0.0726
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.034 0.034
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0036 0.016 0.1815
Giardia lamblia Cathepsin B precursor 0.0036 0.016 0.078
Brugia malayi steroid hormone receptor 0.0031 0.0124 0.0124
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0049 0.0227
Loa Loa (eye worm) hypothetical protein 0.0029 0.0112 0.0111
Loa Loa (eye worm) hypothetical protein 0.0025 0.008 0.0079
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0189 0.0189
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0272 0.0595
Echinococcus multilocularis neuropeptide Y receptor 0.0093 0.06 0.0726
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0054 0.0303 0.0586
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.06 0.0726
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.06 0.0726
Echinococcus multilocularis serotonin receptor 0.0093 0.06 0.0726
Echinococcus granulosus glutamate receptor 2 0.0035 0.0153 0.0185
Onchocerca volvulus Putative cubilin 0.003 0.0114 0.0365
Onchocerca volvulus Matrilysin homolog 0.0048 0.0255 0.1219
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0189 0.0229
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.06 0.0726
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0093 0.06 0.0726
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0612 0.4561 0.8819
Loa Loa (eye worm) hypothetical protein 0.0029 0.0112 0.0111
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0136 0.0929 0.1125
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0036 0.016 0.1815
Echinococcus multilocularis protein jagged 2 0.003 0.0114 0.0138
Echinococcus multilocularis neuropeptides capa receptor 0.0093 0.06 0.0726
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0124 0.0151
Echinococcus granulosus glutamate receptor 2 0.002 0.0041 0.0049
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Onchocerca volvulus Cathepsin L homolog 0.0114 0.0762 0.4277
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0124 0.0124
Loa Loa (eye worm) GABA receptor subunit 0.0029 0.0112 0.0111
Loa Loa (eye worm) hypothetical protein 0.0031 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0013
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0036 0.016 0.1815
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0074 0.0238
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0049 0.0106
Echinococcus granulosus protein jagged 1 0.003 0.0114 0.0138
Giardia lamblia Hypothetical protein 0.0036 0.016 0.078
Brugia malayi Cathepsin L-like precursor 0.0114 0.0762 0.0761
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0036 0.016 0.016
Brugia malayi latrophilin 2 splice variant baaae 0.0071 0.0427 0.0427
Schistosoma mansoni hypothetical protein 0.003 0.0114 0.022
Brugia malayi neuropeptide F receptor 0.0093 0.06 0.06
Giardia lamblia High cysteine protein 0.003 0.0114 0.0468
Entamoeba histolytica cysteine proteinase, putative 0.0068 0.0404 0.5302
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0124 0.0241
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0021 0.0049 0.0227
Brugia malayi RE15519p 0.0093 0.06 0.06
Leishmania major cathepsin L-like protease 0.0114 0.0762 0.3577
Echinococcus multilocularis somatostatin receptor 0.0093 0.06 0.0726
Brugia malayi hypothetical protein 0.0093 0.06 0.06
Loa Loa (eye worm) hypothetical protein 0.0148 0.1021 0.1021
Echinococcus multilocularis neuropeptide receptor A26 0.0093 0.06 0.0726
Onchocerca volvulus 0.0093 0.06 0.33
Trichomonas vaginalis glutaminase, putative 0.0265 0.1911 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0114 0.0762 0.384
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.06 0.0726
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0114 0.0762 0.3577
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0124 0.0151
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Entamoeba histolytica cysteine protease, putative 0.0068 0.0404 0.5302
Loa Loa (eye worm) hypothetical protein 0.0031 0.0124 0.0124
Entamoeba histolytica cysteine proteinase 2 0.0068 0.0404 0.5302
Schistosoma mansoni biogenic amine (5HT) receptor 0.0093 0.06 0.116
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0096 0.0942
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0189 0.0229
Loa Loa (eye worm) hypothetical protein 0.0025 0.008 0.0079
Echinococcus multilocularis G-protein coupled receptor, putative 0.0093 0.06 0.0726
Brugia malayi G protein-coupled receptor F59B2.13 0.0093 0.06 0.06
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0093 0.06 0.0726
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0103 0.0677 0.0676
Echinococcus granulosus neurogenic locus notch protein 4 0.003 0.0114 0.0138
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0124 0.0151
Schistosoma mansoni hypothetical protein 0.003 0.0114 0.022
Loa Loa (eye worm) hypothetical protein 0.0025 0.008 0.0079
Leishmania major hypothetical protein, conserved 0.0031 0.0121 0.0568
Schistosoma mansoni Mername-AA248 (C02 family) 0.0021 0.0049 0.0094
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0096 0.021
Loa Loa (eye worm) hypothetical protein 0.0031 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0082 0.0518 0.0517
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Brugia malayi EGF-like domain containing protein 0.003 0.0114 0.0114
Schistosoma mansoni acetylcholine receptor-related 0.0025 0.008 0.0154
Onchocerca volvulus 0.0238 0.1709 1
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0054 0.0303 0.0367
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0114 0.0762 0.3577
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0093 0.06 0.06
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0124 0.0151
Loa Loa (eye worm) hypothetical protein 0.0029 0.0112 0.0111
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Echinococcus granulosus sex peptide receptor 0.0093 0.06 0.0726
Brugia malayi Tachykinin-like peptides receptor 99D 0.0093 0.06 0.06
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0124 0.0124
Plasmodium falciparum serine repeat antigen 6 0.0036 0.016 0.1815
Echinococcus granulosus protein jagged 1 0.003 0.0114 0.0138
Brugia malayi EGF-like domain containing protein 0.003 0.0114 0.0114
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0093 0.06 0.116
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0114 0.0762 0.3577
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0036 0.016 0.031
Brugia malayi Serotonin receptor 0.0093 0.06 0.06
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0096 0.0942
Loa Loa (eye worm) hypothetical protein 0.0031 0.0124 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.016 0.0617
Echinococcus granulosus calpain 5 0.0021 0.0049 0.0059
Echinococcus granulosus g protein coupled receptor 0.0093 0.06 0.0726
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0324 0.2361 0.2361
Onchocerca volvulus 0.0114 0.0762 0.4277
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0035 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0092 0.0588 0.0588
Schistosoma mansoni hypothetical protein 0.003 0.0114 0.022
Schistosoma mansoni neuropeptide receptor 0.0093 0.06 0.116
Brugia malayi Matrixin family protein 0.0022 0.0054 0.0053
Brugia malayi PHD-finger family protein 0.0053 0.0294 0.0293
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Entamoeba histolytica cysteine protease, putative 0.0068 0.0404 0.5302
Brugia malayi Cadherin domain containing protein 0.003 0.0114 0.0114
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0124 0.0241
Giardia lamblia DINP protein human, muc B family 0.0021 0.0047 0.0015
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.06 0.0726
Brugia malayi hypothetical protein 0.0025 0.008 0.0079
Brugia malayi hypothetical protein 0.0093 0.06 0.06
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0214 0.1521 0.3335
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0126 0.0848 0.1639
Trypanosoma brucei antigen, putative 0.0021 0.0049 0.0227
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.022
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0124 0.0124
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0054 0.0303 0.0367
Schistosoma mansoni hypothetical protein 0.003 0.0114 0.022
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0032 0.0132 0.0131
Onchocerca volvulus 0.0093 0.06 0.33
Echinococcus multilocularis neuropeptide receptor 0.0093 0.06 0.0726
Loa Loa (eye worm) hypothetical protein 0.0018 0.0027 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0114 0.0762 0.384
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0013 0.0013
Echinococcus multilocularis neuropeptide receptor 0.0093 0.06 0.0726
Schistosoma mansoni cathepsin F (C01 family) 0.0082 0.0518 0.1001
Onchocerca volvulus 0.003 0.0114 0.0365
Echinococcus granulosus dna polymerase kappa 0.0021 0.0047 0.0057
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0049 0.0106
Loa Loa (eye worm) hypothetical protein 0.0071 0.0427 0.0427
Schistosoma mansoni nAChR subunit 0.0054 0.0303 0.0586
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0948 0.2078
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.0781 0.4987
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0047 0.0012
Schistosoma mansoni acetylcholine receptor subunit beta 0.0025 0.008 0.0154
Giardia lamblia Cathepsin L precursor 0.0036 0.016 0.078
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0137 0.0137
Echinococcus multilocularis g protein coupled receptor 0.0093 0.06 0.0726
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0013
Entamoeba histolytica hypothetical protein 0.0035 0.0158 0.2066
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0158 0.0191
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Onchocerca volvulus Cathepsin F homolog 0.0114 0.0762 0.4277
Schistosoma mansoni survival motor neuron protein 0.0049 0.0266 0.0514
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0137 0.0137
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0036 0.016 0.0617
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0036 0.016 0.1815
Echinococcus granulosus survival motor neuron protein 1 0.0243 0.1742 0.2109
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0074 0.0275
Echinococcus multilocularis cathepsin L cysteine protease 0.0114 0.0762 0.0922
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0114 0.0762 0.3577
Giardia lamblia Cathepsin B precursor 0.0214 0.1521 1
Entamoeba histolytica Ran family GTPase 0.0021 0.0045 0.0586
Echinococcus multilocularis notch 0.003 0.0114 0.0138
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0123 0.0824 0.0998
Brugia malayi hypothetical protein 0.0093 0.06 0.06
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0124 0.0151
Echinococcus granulosus tm gpcr rhodopsin 0.0093 0.06 0.0726
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0293 0.2128 1
Chlamydia trachomatis glutamine binding protein 0.0019 0.0032 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0093 0.06 0.0726
Plasmodium vivax unspecified product 0.0068 0.0404 0.5133
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0677 0.5059 0.6125
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0074 0.0238
Onchocerca volvulus Neuropeptide F receptor homolog 0.0093 0.06 0.33
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0214 0.1521 0.791
Plasmodium vivax vivapain-1 0.0068 0.0404 0.5133
Echinococcus multilocularis hypothetical protein 0.0021 0.0049 0.0059
Brugia malayi Dopamine receptor 0.0093 0.06 0.06
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0045 0.0248
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0019 0.0032 1
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0049 0.0227
Echinococcus multilocularis nmda type glutamate receptor 0.0033 0.0144 0.0174
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0074 0.0073
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0158 0.0191
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0124 0.0124
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0762 0.384
Trypanosoma cruzi cysteine protease, putative 0.0068 0.0404 0.0885
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0013 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0762 0.384
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0231 0.0279
Loa Loa (eye worm) hypothetical protein 0.0025 0.008 0.0079
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0036 0.016 0.1815
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0054 0.0303 0.0367
Onchocerca volvulus 0.0025 0.008 0.0157
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0054 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0093 0.06 0.06
Schistosoma mansoni glutamate receptor kainate 0.0027 0.0095 0.0185
Brugia malayi Bromodomain containing protein 0.0153 0.1058 0.1057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.06 0.116
Echinococcus granulosus allatostatin A receptor 0.0093 0.06 0.0726
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.022
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0114
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0054 0.0303 0.0367
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0123 0.0824 0.0998
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0036 0.016 0.1815
Loa Loa (eye worm) hypothetical protein 0.0029 0.0112 0.0111
Entamoeba histolytica cysteine protease, putative 0.0068 0.0404 0.5302
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.022
Brugia malayi Delta serrate ligand family protein 0.003 0.0114 0.0114
Loa Loa (eye worm) animal heme peroxidase 0.0092 0.0588 0.0588
Echinococcus granulosus peroxidasin 0.0092 0.0588 0.0712
Echinococcus granulosus protein jagged 2 0.003 0.0114 0.0138
Leishmania major cathepsin L-like protease 0.0114 0.0762 0.3577
Schistosoma mansoni notch 0.003 0.0114 0.022
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0124 0.0124
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0093 0.06 0.06
Loa Loa (eye worm) calpain family protein 1 0.0056 0.0314 0.0314
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0303 0.0303
Entamoeba histolytica cysteine protease, putative 0.0036 0.016 0.2099
Entamoeba histolytica hypothetical protein 0.0023 0.0061 0.0796
Schistosoma mansoni bromodomain containing protein 0.013 0.0879 0.1699
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0054 0.0303 0.0367
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0058 0.0333 0.0404
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0013 0.0025
Brugia malayi EGF-like domain containing protein 0.003 0.0114 0.0114
Echinococcus multilocularis cathepsin L cysteine protease 0.0114 0.0762 0.0922
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0013 0.0016
Schistosoma mansoni calpain-7 (C02 family) 0.0024 0.0072 0.0139
Echinococcus multilocularis glycine receptor subunit beta 0.0054 0.0303 0.0367
Echinococcus granulosus neuropeptides capa receptor 0.0093 0.06 0.0726
Onchocerca volvulus 0.0093 0.06 0.33
Brugia malayi G-protein coupled receptor 0.0093 0.06 0.06
Brugia malayi Dopamine receptor protein 2 0.0093 0.06 0.06
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0124 0.0241
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0214 0.1521 0.2941
Schistosoma mansoni DNA polymerase eta 0.0021 0.0047 0.0091
Brugia malayi calpain family protein 1 0.0056 0.0314 0.0314
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0013
Entamoeba histolytica cysteine proteinase, putative 0.0068 0.0404 0.5302
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0762 0.384
Echinococcus multilocularis neurogenic locus protein delta 0.003 0.0114 0.0138
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0061 0.0086
Schistosoma mansoni hypothetical protein 0.003 0.0114 0.022
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.06 0.0726
Schistosoma mansoni cathepsin S (C01 family) 0.0036 0.016 0.031
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0124 0.0151
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0029 0.0112 0.0111
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0054 0.0303 0.0367
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0124 0.0151
Onchocerca volvulus 0.0114 0.0762 0.4277
Loa Loa (eye worm) hypothetical protein 0.0054 0.0303 0.0303
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0093 0.06 0.116
Echinococcus granulosus cathepsin L 0.0068 0.0404 0.0489
Echinococcus granulosus dnaJ subfamily B 0.0442 0.3265 0.3953
Schistosoma mansoni neuropeptide receptor 0.0093 0.06 0.116
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0047 0.0104

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) = 49 uM Antiproliferative activity against human HT29 cells ChEMBL. 18023585
GI50 (functional) = 49 uM Antiproliferative activity against human HT29 cells ChEMBL. 18023585
IC50 (functional) = 43 uM In vitro cytotoxic activity required to inhibit human chronic myelogenous leukemia K-562 cell line ChEMBL. 14584955
IC50 (functional) = 43 uM In vitro cytotoxic activity required to inhibit human chronic myelogenous leukemia K-562 cell line ChEMBL. 14584955
IC50 (functional) = 47 uM In vitro cytotoxic activity required to inhibit murine lymphocytotic leukemia L1210 cell line ChEMBL. 14584955
IC50 (functional) = 47 uM In vitro cytotoxic activity required to inhibit murine lymphocytotic leukemia L1210 cell line ChEMBL. 14584955
IC50 (functional) = 51 uM Cytotoxic activity of the compound on colchicine-resistant CHO-VV 3-2 cell line expressing mutated tubulin ChEMBL. 14584955
IC50 (functional) = 54 uM Cytotoxic activity of the compound on paclitaxel-resistant CHO-TAX 5-6 cell line expressing mutated tubulin ChEMBL. 14584955
IC50 (functional) = 58 uM Cytotoxic activity of the compound on wild type CHO-10001 cell line expressing mutated tubulin ChEMBL. 14584955
IC50 (functional) = 59 uM In vitro cytotoxic activity required to inhibit human bladder carcinoma T24 cell line ChEMBL. 14584955
IC50 (functional) = 59 uM In vitro cytotoxic activity required to inhibit human bladder carcinoma T24 cell line ChEMBL. 14584955
IC50 (functional) = 76 uM In vitro cytotoxic activity required to inhibit human colon adenocarcinoma HT-29 cell line ChEMBL. 14584955
IC50 (functional) = 76 uM In vitro cytotoxic activity required to inhibit human colon adenocarcinoma HT-29 cell line ChEMBL. 14584955
IC50 (functional) = 93 uM In vitro cytotoxic activity required to inhibit murine melanoma B16 cell line ChEMBL. 14584955
IC50 (functional) = 93 uM In vitro cytotoxic activity required to inhibit human estrogen-sensitive breast adenocarcinoma MCF-7 cell line ChEMBL. 14584955
IC50 (functional) = 93 uM In vitro cytotoxic activity required to inhibit murine melanoma B16 cell line ChEMBL. 14584955
IC50 (functional) = 93 uM In vitro cytotoxic activity required to inhibit human estrogen-sensitive breast adenocarcinoma MCF-7 cell line ChEMBL. 14584955

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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