Detailed information for compound 257516

Basic information

Technical information
  • TDR Targets ID: 257516
  • Name: 1,4-Methano-s-indacene-3a(1H)-carboxylic acid , 8a-[2-(benzoyloxy)ethyl]-4-formyl-4,4a,5,6, 7,7a,8,8a-octahydro-7-methyl-3-(1-methylethyl )-, (7R)-
  • MW: 450.567 | Formula: C28H34O5
  • H donors: 1 H acceptors: 4 LogP: 4.83 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=CC12CC3C(C2(C(=O)O)C(=C3)C(C)C)(CC2C1CC[C@H]2C)CCOC(=O)c1ccccc1
  • InChi: 1S/C28H34O5/c1-17(2)23-13-20-14-27(16-29)22-10-9-18(3)21(22)15-26(20,28(23,27)25(31)32)11-12-33-24(30)19-7-5-4-6-8-19/h4-8,13,16-18,20-22H,9-12,14-15H2,1-3H3,(H,31,32)/t18-,20?,21?,22?,26?,27?,28?/m1/s1
  • InChiKey: MQDVQACAJARLJR-YIJFEYSDSA-N  


Substructure search Similarity search

Network

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Synonyms

  • AIDS-228123
  • AIDS228123

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0277 0.1046 0.3026
Onchocerca volvulus 0.0082 0.0264 0.0656
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0072 0.0221 0.0635
Mycobacterium tuberculosis Probable bifunctional penicillin-binding protein 1A/1B PonA1 (murein polymerase) (PBP1): penicillin-insensitive transglycosylase 0.043 0.1658 0.2953
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0054 0.0148 0.0278
Toxoplasma gondii peptidylprolyl isomerase 0.007 0.0214 0.1558
Loa Loa (eye worm) hypothetical protein 0.0183 0.0668 0.1932
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1246 0.4936 0.9297
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0045 0.005
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0075 0.0546
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0085 0.0274 0.048
Brugia malayi 6-phosphofructokinase 0.0233 0.0868 0.2508
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1246 0.4936 0.9297
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0006 0.0041
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.006 0.0175 0.1282
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0357 0.1366 1
Onchocerca volvulus 0.0079 0.0252 0.0626
Trypanosoma cruzi transcription factor btf3, putative 0.0072 0.0223 0.1629
Echinococcus multilocularis apoptotic protease activating factor 1 0.0032 0.0062 0.0069
Onchocerca volvulus 0.002 0.0011 0.0015
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0031 0.0059
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.0019 0.001 0.0028
Toxoplasma gondii histone lysine demethylase JMJD6a 0.002 0.0012 0.0079
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0075 0.0546
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0079 0.0252 0.0725
Loa Loa (eye worm) matrixin family protein 0.0044 0.0109 0.0315
Giardia lamblia PHD finger protein 15 0.0061 0.0178 0.0362
Trypanosoma brucei DNA polymerase IV, putative 0.0212 0.0783 0.5734
Brugia malayi Hemopexin family protein 0.0026 0.0036 0.01
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.0006 0.0006
Echinococcus multilocularis lamin 0.0058 0.0165 0.0184
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0016
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0131 0.0459 0.336
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.002 0.0012 0.0089
Schistosoma mansoni microtubule-associated protein tau 0.2257 0.8998 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.006 0.0175 0.1282
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0001 0.0003
Echinococcus multilocularis microtubule associated protein 2 0.2257 0.8998 1
Mycobacterium ulcerans pyruvate kinase 0.0037 0.0081 0.0089
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0022 0.002 0.015
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0047 0.0053
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0186 0.0349
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.002 0.0013 0.0086
Echinococcus granulosus lysine specific demethylase 6a 0.002 0.0012 0.0014
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0024 0.0031 0.0086
Giardia lamblia Transcriptional regulator, Sir2 family 0.0054 0.0148 0.0299
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0028 0.0047 0.0051
Brugia malayi Pre-SET motif family protein 0.0878 0.3457 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0061 0.0178 0.0197
Loa Loa (eye worm) flap endonuclease-1 0.0029 0.0048 0.014
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0031 0.0059
Brugia malayi Bromodomain containing protein 0.0061 0.0178 0.0512
Loa Loa (eye worm) hypothetical protein 0.0032 0.0062 0.0179
Loa Loa (eye worm) hypothetical protein 0.0079 0.0252 0.0729
Entamoeba histolytica phosphofructokinase, putative 0.0233 0.0868 0.1756
Toxoplasma gondii NAC domain-containing protein 0.0072 0.0223 0.162
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0508 0.1972 0.3514
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0221 0.0416
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0024 0.0031 0.0035
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0031 0.0059
Schistosoma mansoni hypothetical protein 0.0537 0.2091 0.2323
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0031 0.0059
Onchocerca volvulus 0.0019 0.001 0.0011
Mycobacterium leprae PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) [INCLUDES: PENICILLIN-INSEN 0.1085 0.429 0.765
Echinococcus multilocularis pyruvate kinase 0.0037 0.0081 0.0091
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.0403 0.0448
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0081 0.0236
Schistosoma mansoni hypothetical protein 0.0061 0.0178 0.0197
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0028 0.0047 0.0053
Schistosoma mansoni lamin 0.0058 0.0165 0.0182
Trichomonas vaginalis hypothetical protein 0.0024 0.0031 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.0047 0.0133
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0026 0.0008
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0032 0.0062 0.0069
Brugia malayi Phosphoglycerate kinase 0.0131 0.0459 0.1324
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0783 0.5734
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0106
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0022 0.002 0.0139
Trichomonas vaginalis chromobox protein, putative 0.015 0.0534 0.1005
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0054 0.0148 0.0254
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0079 0.0252 0.0729
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0006 0.0012
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0017 0.0001 0.0002
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0137 0.0483 0.0853
Echinococcus multilocularis expressed protein 0.0072 0.0221 0.0246
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0198 0.0728 0.1371
Mycobacterium leprae PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC 0.0296 0.1123 0.1974
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0186 0.0349
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0175 0.033
Brugia malayi hypothetical protein 0.0024 0.0031 0.0086
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.009
Schistosoma mansoni RAR-like nuclear receptor 0.0028 0.0047 0.0051
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0137
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1246 0.4936 1
Loa Loa (eye worm) doublecortin family protein 0.002 0.0011 0.0033
Toxoplasma gondii ImpB/MucB/SamB family protein 0.004 0.0093 0.067
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0054 0.0148 0.0278
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0031 0.0059
Loa Loa (eye worm) glutathione reductase 0.0052 0.0142 0.0412
Loa Loa (eye worm) hypothetical protein 0.0137 0.0482 0.1394
Echinococcus multilocularis jumonji domain containing protein 0.0085 0.0275 0.0305
Trichomonas vaginalis flap endonuclease-1, putative 0.0029 0.0048 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.027 0.0508
Chlamydia trachomatis transglycolase/transpeptidase 0.116 0.4592 0.4589
Echinococcus multilocularis jumonji domain containing 1A 0.002 0.0012 0.0014
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0357 0.1366 1
Toxoplasma gondii proteasome regulatory subunit 0.0022 0.0021 0.0144
Schistosoma mansoni flap endonuclease-1 0.0026 0.0037 0.004
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0023 0.0043
Trypanosoma brucei trypanothione reductase 0.0052 0.0142 0.1043
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0063 0.0186 0.1349
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0028 0.0047 0.0133
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.02 0.0737 0.0819
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0029 0.0048 0.0354
Trypanosoma brucei DNA damage repair protein, putative 0.004 0.0093 0.068
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0012 0.0089
Mycobacterium tuberculosis Conserved protein 0.0079 0.0252 0.0441
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0181 0.0661 0.0735
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0017 0.0001 0.0011
Mycobacterium leprae Probable transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) 0.0176 0.0639 0.1106
Plasmodium vivax pyruvate kinase, putative 0.0037 0.0081 0.0586
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0031 0.0033
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0198 0.0728 0.1371
Toxoplasma gondii phosphoinositide phospholipase PIPLC 0.0019 0.001 0.0061
Giardia lamblia Sirtuin type 2 0.0017 0.0001 0.0003
Leishmania major sir2-family protein-like protein 0.0017 0.0001 0.0011
Echinococcus granulosus pyruvate kinase 0.0019 0.0009 0.001
Mycobacterium tuberculosis Conserved hypothetical protein 0.0128 0.0448 0.0791
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0004
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0128 0.0448 0.0498
Brugia malayi steroid hormone receptor 0.0028 0.0047 0.0133
Trypanosoma cruzi DNA damage repair protein, putative 0.004 0.0093 0.068
Plasmodium falciparum glutathione reductase 0.0018 0.0006 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0783 0.5734
Echinococcus multilocularis chromobox protein 2 0.0024 0.0031 0.0035
Mycobacterium leprae Probable lipase LipE 0.0079 0.0252 0.0413
Brugia malayi ecdysteroid receptor 0.0028 0.0047 0.0133
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0031 0.0059
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0028 0.0047 0.0106
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0017 0.0001 0.0002
Echinococcus granulosus 6 phosphofructokinase 0.0233 0.0868 0.0965
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0252 0.0475
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0028 0.0047 0.0053
Plasmodium falciparum heterochromatin protein 1 0.0024 0.0031 0.0218
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0031 0.006
Brugia malayi ImpB/MucB/SamB family protein 0.0183 0.0668 0.1928
Chlamydia trachomatis phosphoglycerate kinase 0.0357 0.1366 0.1361
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0233 0.0868 0.6353
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0062 0.0177
Trypanosoma brucei DNA polymerase kappa, putative 0.0109 0.0371 0.2719
Entamoeba histolytica Flap nuclease, putative 0.0029 0.0048 0.0095
Onchocerca volvulus 0.0079 0.0252 0.0626
Treponema pallidum penicillin-binding protein (pbp-2) 0.1339 0.531 0.5307
Trypanosoma brucei unspecified product 0.0088 0.0288 0.211
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0031 0.0059
Echinococcus granulosus phosphoglycerate kinase 1 0.0357 0.1366 0.1519
Echinococcus multilocularis lysine specific demethylase 5A 0.0074 0.023 0.0256
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0023 0.0024
Leishmania major hypothetical protein, conserved 0.0079 0.0252 0.1845
Plasmodium vivax JmjC domain containing protein 0.002 0.0012 0.0079
Schistosoma mansoni phosphoglycerate kinase 0.0357 0.1366 0.1517
Loa Loa (eye worm) hypothetical protein 0.0357 0.1366 0.3952
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1246 0.4936 0.9297
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0023 0.0061
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0031 0.0033
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0031 0.0033
Mycobacterium ulcerans phosphoglycerate kinase 0.0357 0.1366 0.1518
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0609 0.2377 0.2643
Entamoeba histolytica transcription factor BTF3, putative 0.0072 0.0223 0.0448
Echinococcus granulosus chromobox protein 1 0.015 0.0534 0.0593
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0252 0.0475
Trichomonas vaginalis phosphofructokinase, putative 0.0233 0.0868 0.1635
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.0252 0.1845
Plasmodium falciparum pyruvate kinase 2 0.0019 0.0009 0.0056
Trichomonas vaginalis phosphofructokinase, putative 0.0233 0.0868 0.1635
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0031 0.0059
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0119 0.0411 0.0724
Echinococcus multilocularis dna polymerase eta 0.0183 0.0668 0.0742
Echinococcus granulosus peregrin 0.0061 0.0178 0.0198
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0028 0.0047 0.0137
Echinococcus multilocularis dna polymerase kappa 0.0212 0.0783 0.0871
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0357 0.1366 0.241
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0013 0.0096
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0081 0.0236
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.006 0.0175 0.1282
Leishmania major DNA damage repair protein, putative 0.004 0.0093 0.068
Trypanosoma brucei unspecified product 0.0191 0.07 0.5125
Trypanosoma brucei phosphoglycerate kinase 0.0357 0.1366 1
Trichomonas vaginalis DNA polymerase eta, putative 0.0212 0.0783 0.1475
Echinococcus multilocularis neuropeptide s receptor 0.0517 0.2009 0.2233
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0022 0.0021 0.0023
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0022 0.0021 0.004
Trichomonas vaginalis glutathione reductase, putative 0.0018 0.0006 0.001
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0198 0.0728 0.1371
Loa Loa (eye worm) thioredoxin reductase 0.0052 0.0142 0.0412
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0252 0.0279
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0063 0.0186 0.018
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0028 0.0047 0.0053
Echinococcus granulosus transcription factor btf3 0.0072 0.0223 0.0247
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0022 0.002 0.015
Echinococcus multilocularis thioredoxin glutathione reductase 0.0052 0.0142 0.0158
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0066 0.0197 0.0219
Leishmania major DNA polymerase eta, putative 0.0183 0.0668 0.4888
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0093 0.068
Toxoplasma gondii pyruvate kinase PyKII 0.0019 0.0009 0.0056
Mycobacterium ulcerans epimerase 0.0022 0.0023 0.0024
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0047 0.0051
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0128 0.0448 0.1296
Schistosoma mansoni chromobox protein 0.0024 0.0031 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0191 0.036
Loa Loa (eye worm) PHD-finger family protein 0.0061 0.0178 0.0516
Loa Loa (eye worm) ICD-1 protein 0.0072 0.0223 0.0644
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0062 0.0177
Schistosoma mansoni lipoxygenase 0.0117 0.0403 0.0446
Schistosoma mansoni polycystin 1-related 0.002 0.0011 0.0011
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0357 0.1366 0.2573
Echinococcus granulosus PHD finger protein rhinoceros 0.0061 0.0178 0.0198
Echinococcus granulosus microtubule associated protein 2 0.2257 0.8998 1
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0006 0.0005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0047 0.0053
Schistosoma mansoni intermediate filament proteins 0.0058 0.0165 0.0182
Trichomonas vaginalis DNA helicase recq, putative 0.0047 0.0121 0.0228
Echinococcus granulosus ubiquitin 0.0023 0.0023 0.0026
Brugia malayi jmjC domain containing protein 0.002 0.0012 0.0031
Brugia malayi Matrixin family protein 0.0044 0.0109 0.031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0028 0.0047 0.0137
Plasmodium vivax heterochromatin protein 1, putative 0.0024 0.0031 0.0218
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0017 0.0001 0.0011
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0012 0.0035
Onchocerca volvulus Matrix metalloproteinase homolog 0.004 0.0094 0.0225
Brugia malayi Protein cec-1. 0.0024 0.0031 0.0086
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0001 0.0003
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0026 0.0037
Brugia malayi glutathione reductase 0.0052 0.0142 0.0408
Trichomonas vaginalis conserved hypothetical protein 0.1339 0.531 1
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0011 0.0013
Trypanosoma cruzi DNA polymerase kappa, putative 0.0212 0.0783 0.5734
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0028 0.0047 0.0133
Chlamydia trachomatis pyruvate kinase 0.0037 0.0081 0.0076
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0132 0.0464 0.082
Trypanosoma brucei DNA polymerase IV, putative 0.0212 0.0783 0.5734
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0137
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0011 0.0073
Schistosoma mansoni ap endonuclease 0.006 0.0175 0.0193
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0022 0.002 0.015
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0001 0.0003
Schistosoma mansoni chromobox protein 0.015 0.0534 0.0592
Plasmodium vivax NAD-dependent deacetylase, putative 0.0054 0.0148 0.1073
Giardia lamblia Pyruvate kinase 0.0019 0.0009 0.0019
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0438 0.0486
Plasmodium falciparum phosphoinositide-specific phospholipase C 0.0018 0.0005 0.0029
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0085 0.0274 0.0789
Brugia malayi CHD4 protein 0.0024 0.0031 0.0086
Onchocerca volvulus Matrilysin homolog 0.004 0.0094 0.0225
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0032 0.0034
Trypanosoma cruzi DNA polymerase eta, putative 0.0095 0.0312 0.2287
Brugia malayi hypothetical protein 0.0023 0.0023 0.0063
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0001 0.0003
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0131 0.0459 0.336
Trichomonas vaginalis mercuric reductase, putative 0.0018 0.0006 0.001
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0031 0.0059
Mycobacterium tuberculosis Probable penicillin-binding protein PbpA 0.1412 0.5602 1
Toxoplasma gondii thioredoxin reductase 0.0052 0.0142 0.1033
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0252 0.0279
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0024 0.0031 0.0035
Echinococcus granulosus Solute carrier family 22 5 0.1142 0.4521 0.5025
Brugia malayi photoreceptor-specific nuclear receptor 0.0028 0.0047 0.0133
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0028 0.0047 0.0133
Treponema pallidum hypothetical protein 0.0176 0.0639 0.0634
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0063 0.0186 0.0373
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0028 0.0047 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0031 0.0059
Echinococcus multilocularis lamin dm0 0.0058 0.0165 0.0184
Treponema pallidum phosphoglycerate kinase 0.0357 0.1366 0.1361
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0081 0.0153
Wolbachia endosymbiont of Brugia malayi cell division protein FtsI 0.2507 1 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0031 0.006
Trypanosoma brucei SIR2-like protein 4, putative 0.0017 0.0001 0.0011
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.0064 0.0191 0.0211
Brugia malayi SET domain containing protein 0.0029 0.005 0.014
Toxoplasma gondii pyruvate kinase PyK1 0.0037 0.0081 0.0586
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0016 0.0019
Schistosoma mansoni rotamase 0.0072 0.0221 0.0244
Loa Loa (eye worm) glutaminase 2 0.0555 0.2162 0.6253
Echinococcus multilocularis lysine specific demethylase 6a 0.002 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0057 0.0161 0.0466
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1246 0.4936 0.9297
Brugia malayi Cell death protein 3 precursor 0.0032 0.0062 0.0175
Chlamydia trachomatis endonuclease IV 0.0085 0.0274 0.0269
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.0006 0.003
Onchocerca volvulus 0.0024 0.0031 0.0065
Schistosoma mansoni 6-phosphofructokinase 0.0233 0.0868 0.0963
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0011 0.0013
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0119 0.0411 0.0724
Toxoplasma gondii ABC1 family protein 0.0079 0.0252 0.1836
Echinococcus multilocularis Chromo domain 0.0024 0.0031 0.0035
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0028
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.007 0.0214 0.1567
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0018 0.0006 0.0005
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0128 0.0448 0.0497
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0031 0.0218
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.007 0.0214 0.1567
Mycobacterium ulcerans DNA polymerase IV 0.0212 0.0783 0.087
Echinococcus granulosus chromatin regulatory protein sir2 0.0017 0.0001 0.0002
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0012 0.0089
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1246 0.4936 1
Mycobacterium leprae Probable penicillin-binding protein PbpA 0.1412 0.5602 1
Plasmodium falciparum nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.0296 0.1123 0.8218
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0277 0.1046 0.7656
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.0006 0.003
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0028 0.0047 0.0133
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.002 0.0012 0.0012
Toxoplasma gondii exonuclease III APE 0.006 0.0175 0.1272
Trypanosoma cruzi DNA polymerase eta, putative 0.0183 0.0668 0.4888
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0075 0.0546
Brugia malayi jmjC domain containing protein 0.002 0.0012 0.0031
Giardia lamblia Phosphoglycerate kinase 0.0357 0.1366 0.2768
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0084 0.027 0.067
Mycobacterium tuberculosis Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) 0.0176 0.0639 0.1131
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0054 0.0148 0.0297
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.009
Plasmodium vivax SET domain protein, putative 0.0126 0.0438 0.3201
Mycobacterium tuberculosis Probable penicillin-binding membrane protein PbpB 0.0657 0.257 0.4582
Loa Loa (eye worm) hypothetical protein 0.0082 0.0264 0.0764
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0132 0.0463 0.134
Giardia lamblia Hypothetical protein 0.0017 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0028 0.0045 0.0131
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0081 0.0236
Trichomonas vaginalis phosphofructokinase, putative 0.0233 0.0868 0.1635
Mycobacterium ulcerans lipase LipD 0.0079 0.0252 0.0279
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0017 0.0001 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0783 0.5734
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.007 0.0214 0.0431
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0233 0.0868 0.6353
Mycobacterium ulcerans penicillin-binding lipoprotein 0.0803 0.316 0.3513
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.006 0.0175 0.0507
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0033
Plasmodium vivax basic transcription factor 3b, putative 0.0072 0.0223 0.162
Echinococcus granulosus histone lysine methyltransferase setb 0.0126 0.0438 0.0487
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0.0013 0.0086
Trypanosoma brucei DNA polymerase IV, putative 0.0191 0.07 0.5125
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0043 0.0106 0.0116
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0181 0.0661 0.0733
Leishmania major phospholipase c-like protein 0.0019 0.001 0.0072
Schistosoma mansoni 6-phosphofructokinase 0.0233 0.0868 0.0963
Plasmodium vivax phosphoglycerate kinase, putative 0.0357 0.1366 1
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0026 0.018
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0609 0.2377 0.4238
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0031 0.0059
Loa Loa (eye worm) hypothetical protein 0.0123 0.0428 0.1238
Mycobacterium tuberculosis Probable oxidoreductase 0.0132 0.0464 0.082
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0137
Trypanosoma brucei phosphoglycerate kinase 0.0357 0.1366 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0031 0.0059
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0016
Brugia malayi beta-lactamase 0.0079 0.0252 0.0725
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0198 0.0728 0.2103
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0028
Brugia malayi 6-phosphofructokinase 0.0233 0.0868 0.2508
Giardia lamblia Fructose-bisphosphate aldolase 0.1246 0.4936 1
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0026 0.018
Echinococcus multilocularis musashi 0.0058 0.0165 0.0184
Loa Loa (eye worm) hypothetical protein 0.0105 0.0354 0.1024
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0024 0.0031 0.0218
Brugia malayi exodeoxyribonuclease III family protein 0.006 0.0175 0.0503
Brugia malayi Bloom's syndrome protein homolog 0.0047 0.0121 0.0347
Treponema pallidum fructose-bisphosphate aldolase 0.1246 0.4936 0.4933
Entamoeba histolytica hypothetical protein 0.0024 0.0031 0.006
Trichomonas vaginalis glutaminase, putative 0.0555 0.2162 0.4072
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0119 0.0411 0.0698
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0035
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0006 0.0041
Trichomonas vaginalis phosphofructokinase, putative 0.0233 0.0868 0.1635
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0018 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0021 0.0062
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0246 0.092 0.2661
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0006 0.0041
Schistosoma mansoni pyruvate kinase 0.0037 0.0081 0.0089
Brugia malayi Valyl-tRNA synthetase 0.0024 0.0031 0.0086
Trichomonas vaginalis esterase, putative 0.0079 0.0252 0.0475
Schistosoma mansoni lipoxygenase 0.0082 0.0261 0.0289
Onchocerca volvulus 0.0032 0.0062 0.0143
Entamoeba histolytica hypothetical protein 0.0072 0.0223 0.0448
Mycobacterium tuberculosis Probable esterase LipL 0.0079 0.0252 0.0441
Mycobacterium tuberculosis Probable reductase 0.0119 0.0411 0.0724
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0011 0.0013
Toxoplasma gondii endonuclease IV APN 0.0085 0.0274 0.1998
Plasmodium falciparum phd finger protein, putative 0.0061 0.0178 0.1297
Onchocerca volvulus 0.0058 0.0165 0.0406
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0029 0.0048 0.0344
Schistosoma mansoni phosphoglycerate kinase 0.0357 0.1366 0.1517
Treponema pallidum penicillin-binding protein (pbp-1) 0.2507 1 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.0047 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0223 0.0419
Schistosoma mansoni hypothetical protein 0.0537 0.2091 0.2323
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0001 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0031 0.0059
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0026 0.0021
Schistosoma mansoni thyroid hormone receptor 0.0028 0.0047 0.0051
Giardia lamblia NADH oxidase lateral transfer candidate 0.0018 0.0006 0.0011
Schistosoma mansoni thyroid hormone receptor 0.0028 0.0047 0.0051
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0186 0.0349
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.0006 0.0006
Mycobacterium tuberculosis Probable lipase LipE 0.0079 0.0252 0.0441
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0093 0.068
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0047 0.0053
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0186 0.0349
Mycobacterium ulcerans bifunctional penicillin-binding protein 1A/1B PonA1 0.1339 0.531 0.5905
Entamoeba histolytica deoxycytidyl transferase, putative 0.0128 0.0448 0.0905
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0181 0.0661 0.0735
Leishmania major basic transcription factor 3a, putative 0.0072 0.0223 0.1629
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0131 0.0459 0.336
Mycobacterium ulcerans bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein 0.0296 0.1123 0.1248
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0233 0.0868 0.1517
Plasmodium vivax nicotinate-nucleotide adenylyltransferase, putative 0.0296 0.1123 0.8218
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0031 0.0059
Loa Loa (eye worm) 6-phosphofructokinase 0.0233 0.0868 0.2511
Echinococcus granulosus phd:f box containing protein 0.002 0.0012 0.0014
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0054 0.0148 0.1082
Trypanosoma brucei phosphoglycerate kinase 0.0131 0.0459 0.336
Echinococcus granulosus flap endonuclease 1 0.0029 0.0048 0.0054
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0054 0.0148 0.1082
Loa Loa (eye worm) hypothetical protein 0.0079 0.0252 0.0729
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.0038
Echinococcus granulosus pyruvate kinase 0.0037 0.0081 0.0091
Brugia malayi glutaminase DH11.1 0.0555 0.2162 0.6252
Trichomonas vaginalis set domain proteins, putative 0.0999 0.3944 0.7428
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0063 0.0186 0.018
Echinococcus multilocularis flap endonuclease 1 0.0029 0.0048 0.0054
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0011 0.0013
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0066 0.0197 0.0219
Brugia malayi 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 0.0018 0.0005 0.0012
Echinococcus multilocularis ecdysone induced protein 78C 0.0028 0.0047 0.0053
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0072 0.0221 0.0639
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0032 0.0062 0.0069
Onchocerca volvulus 0.002 0.0011 0.0015
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0026 0.0021
Echinococcus multilocularis bloom syndrome protein 0.0047 0.0121 0.0135
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0019 0.001 0.0024
Echinococcus multilocularis Chromobox protein 3 0.0024 0.0031 0.0035
Echinococcus granulosus apoptotic protease activating factor 1 0.0032 0.0062 0.0069
Toxoplasma gondii small ubiquitin family modifier, putative 0.0064 0.0191 0.1391
Leishmania major phosphoglycerate kinase C, glycosomal 0.0357 0.1366 1
Schistosoma mansoni pyruvate kinase 0.0037 0.0081 0.0089
Echinococcus multilocularis chromatin regulatory protein sir2 0.0017 0.0001 0.0002
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0024 0.0031 0.0218
Echinococcus granulosus bloom syndrome protein 0.0047 0.0121 0.0135
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0031 0.0218
Schistosoma mansoni loxhd1 0.002 0.0011 0.0011
Leishmania major pyruvate kinase 0.0037 0.0081 0.0596
Brugia malayi Pyruvate kinase, M2 isozyme 0.0037 0.0081 0.0231
Trypanosoma brucei DNA damage repair protein, putative 0.004 0.0093 0.068
Trypanosoma cruzi phosphoinositide-specific phospholipase C, putative 0.0019 0.001 0.0072
Schistosoma mansoni coup transcription factor 0.0028 0.0047 0.0051
Onchocerca volvulus 0.015 0.0537 0.1349
Trichomonas vaginalis DNA helicase recq, putative 0.0035 0.0075 0.0141
Brugia malayi AF-10 protein 0.002 0.0013 0.0034
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0006 0.0041
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0067
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0018 0.0006 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.027 0.0508
Leishmania major hypothetical protein, conserved 0.002 0.0012 0.0089
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0044 0.0109 0.0789
Leishmania major DNA polymerase kappa, putative 0.004 0.0093 0.068
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0131 0.0459 0.336
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.007 0.0214 0.1567
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0035
Plasmodium falciparum small ubiquitin-related modifier 0.0064 0.0191 0.1391
Echinococcus multilocularis ubiquitin 0.0023 0.0023 0.0026
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0081 0.0192
Echinococcus granulosus jumonji domain containing 1A 0.002 0.0012 0.0014
Mycobacterium tuberculosis Conserved protein 0.0079 0.0252 0.0441
Trypanosoma cruzi transcription factor btf3, putative 0.0072 0.0223 0.1629
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0031 0.0059
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0028 0.0047 0.0051
Trichomonas vaginalis rotamase, putative 0.007 0.0214 0.0403
Loa Loa (eye worm) pyruvate kinase-PB 0.0026 0.0036 0.0106
Mycobacterium ulcerans endonuclease IV 0.0085 0.0274 0.0303
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0085 0.0274 0.0453
Schistosoma mansoni caspase-7 (C14 family) 0.0032 0.0062 0.0067
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.0006 0.003
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.0006 0.003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1246 0.4936 0.9297
Echinococcus granulosus FTZ F1 alpha 0.0028 0.0047 0.0053
Loa Loa (eye worm) transcriptional regulator 0.0017 0.0001 0.0004
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0121 0.042 0.0467
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0033
Trypanosoma cruzi DNA polymerase kappa, putative 0.0212 0.0783 0.5734
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0066
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0032 0.0062 0.0181
Mycobacterium ulcerans hydrolase 0.0022 0.0021 0.0022
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.006 0.0175 0.0355
Leishmania major DNA polymerase kappa, putative 0.0149 0.0531 0.3889
Brugia malayi phosphofructokinase 0.0233 0.0868 0.2508
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0006 0.0041
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0057 0.0162
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0149 0.0531 0.3889
Trichomonas vaginalis DNA helicase recq1, putative 0.0047 0.0121 0.0228
Plasmodium falciparum JmjC domain-containing protein, putative 0.002 0.0012 0.0079
Echinococcus multilocularis pyruvate kinase 0.0037 0.0081 0.0091
Mycobacterium leprae conserved hypothetical protein 0.0079 0.0252 0.0413
Onchocerca volvulus 0.0066 0.0197 0.0486
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.0047 0.0133
Mycobacterium tuberculosis Probable dehydrogenase 0.0119 0.0411 0.0724
Onchocerca volvulus 0.0079 0.0252 0.0626
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0198 0.0728 0.1475
Echinococcus granulosus chromobox protein 2 0.0024 0.0031 0.0035
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0181 0.0661 0.0734
Onchocerca volvulus 0.0028 0.0047 0.0106
Echinococcus multilocularis caspase 2 0.0032 0.0062 0.0069
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0081 0.0596
Brugia malayi beta-lactamase family protein 0.0079 0.0252 0.0725
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0017 0.0001 0.0002
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0026 0.0191
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0026 0.0191
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.023 0.0254
Mycobacterium leprae Probable penicillin-binding membrane protein PbpB 0.0657 0.257 0.4567
Entamoeba histolytica pyruvate kinase, putative 0.0026 0.0036 0.0071
Echinococcus granulosus caspase 2 0.0032 0.0062 0.0069
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0017 0.0001 0.0002
Mycobacterium ulcerans penicillin-binding protein PbpA 0.1412 0.5602 0.623
Echinococcus multilocularis beta LACTamase domain containing family member 0.0079 0.0252 0.028
Loa Loa (eye worm) jmjC domain-containing protein 0.0074 0.023 0.0666
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0783 0.5734
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0061 0.0178 0.0335
Onchocerca volvulus 0.0023 0.0023 0.0045
Toxoplasma gondii phosphofructokinase PFKII 0.0063 0.0186 0.1349
Schistosoma mansoni DNA polymerase IV / kappa 0.004 0.0093 0.0102
Brugia malayi hypothetical protein 0.002 0.0011 0.0029
Echinococcus granulosus thioredoxin glutathione reductase 0.0052 0.0142 0.0158
Toxoplasma gondii PHD-finger domain-containing protein 0.0061 0.0178 0.1297
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0131 0.0459 0.336
Plasmodium falciparum basic transcription factor 3b, putative 0.0072 0.0223 0.162
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.007 0.0214 0.1567
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0079 0.0252 0.0441
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0047 0.0053
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0006 0.0041
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.009
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0081 0.0192
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0018 0.0006 0.003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0006 0.0041
Giardia lamblia Pyruvate kinase 0.0037 0.0081 0.0165
Brugia malayi M-phase phosphoprotein, mpp8 0.0024 0.0031 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.0047 0.0133
Echinococcus granulosus jumonji domain containing protein 0.0085 0.0275 0.0305
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0198 0.0728 0.1473
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0024 0.0031 0.0035
Echinococcus granulosus pyruvate kinase 0.0019 0.0009 0.001
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.006 0.0175 0.017
Schistosoma mansoni hypothetical protein 0.002 0.0013 0.0013
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0006 0.0041
Echinococcus granulosus neuropeptide receptor A26 0.0517 0.2009 0.2233
Loa Loa (eye worm) CHromoDomain protein family member 0.0024 0.0031 0.009
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0095 0.0312 0.2279
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.02 0.0737 0.0819
Leishmania major phosphoinositide-specific phospholipase C, putative 0.0018 0.0005 0.004
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0212 0.0783 0.1475
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0093 0.068
Plasmodium vivax pyruvate kinase 2, putative 0.0019 0.0009 0.0056
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0175 0.1272
Schistosoma mansoni glutaminase 0.0555 0.2162 0.2401
Plasmodium vivax hypothetical protein, conserved 0.0079 0.0252 0.1836
Giardia lamblia Sentrin 0.0064 0.0191 0.0388
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0006 0.0041
Brugia malayi hypothetical protein 0.002 0.0011 0.0029
Schistosoma mansoni ap endonuclease 0.006 0.0175 0.0193
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0028 0.0047 0.0051
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0043 0.0305
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0006 0.0041
Trypanosoma brucei DNA polymerase kappa, putative 0.0109 0.0371 0.2719
Brugia malayi Matrixin family protein 0.0018 0.0006 0.0012
Echinococcus multilocularis RUN 0.002 0.0011 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0028 0.0047 0.0133
Echinococcus multilocularis phd:f box containing protein 0.002 0.0012 0.0014
Trichomonas vaginalis chromobox protein, putative 0.009 0.0295 0.0556
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0132 0.0464 0.082
Schistosoma mansoni transcription factor btf3 0.0072 0.0223 0.0246
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0357 0.1366 0.1361
Schistosoma mansoni steroid hormone receptor ad4bp 0.0028 0.0047 0.0051
Echinococcus multilocularis peregrin 0.0061 0.0178 0.0198
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0022 0.002 0.015
Trichomonas vaginalis ubiquitin, putative 0.0023 0.0023 0.0044
Mycobacterium ulcerans DNA polymerase IV 0.0212 0.0783 0.087
Schistosoma mansoni DNA helicase recq5 0.0032 0.0062 0.0068
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0013 0.0096
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0357 0.1366 0.2573
Onchocerca volvulus Protein ultraspiracle homolog 0.0028 0.0047 0.0106
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0006 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.0047 0.0133
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0031 0.0059
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0198 0.0728 0.1371
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0054 0.0148 0.0278
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0119 0.0411 0.0724
Trichomonas vaginalis Heterochromatin protein, putative 0.0024 0.0031 0.0059
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0031 0.0059
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1246 0.4936 0.9297
Brugia malayi Matrixin family protein 0.0018 0.0006 0.0012
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0126 0.0438 0.0487
Trypanosoma brucei unspecified product 0.0088 0.0288 0.211
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0022 0.0021 0.0144
Loa Loa (eye worm) hypothetical protein 0.0027 0.0041 0.0118
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0001 0.0003
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0175 0.1272
Loa Loa (eye worm) hypothetical protein 0.0037 0.0081 0.0236
Trypanosoma cruzi DNA polymerase kappa, putative 0.0212 0.0783 0.5734
Brugia malayi jmjC domain containing protein 0.002 0.0012 0.0031
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0012 0.0035
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.006 0.0175 0.1282
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0357 0.1366 1
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0011 0.0073
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0022 0.002 0.0015
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0142 0.1043
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0031 0.006
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0079 0.0252 0.0441
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0081 0.0192
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0028 0.0047 0.0137
Leishmania major phosphatidylinositol-specific phospholipase-like protein 0.0018 0.0005 0.004
Mycobacterium ulcerans hypothetical protein 0.0022 0.0023 0.0024
Trichomonas vaginalis rotamase, putative 0.0072 0.0221 0.0416
Echinococcus multilocularis pyruvate kinase 0.0019 0.0009 0.001
Echinococcus multilocularis pyruvate kinase 0.0019 0.0009 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0006 0.0041
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0186 0.0349
Trypanosoma brucei DNA polymerase kappa, putative 0.0109 0.0371 0.2719
Loa Loa (eye worm) SMO-1 protein 0.0064 0.0191 0.0553
Echinococcus granulosus lamin dm0 0.0058 0.0165 0.0184
Brugia malayi jmjC domain containing protein 0.0074 0.023 0.0662
Trypanosoma brucei DNA polymerase kappa, putative 0.0123 0.0428 0.3133
Echinococcus multilocularis PHD finger protein rhinoceros 0.0061 0.0178 0.0198
Toxoplasma gondii PHD-finger domain-containing protein 0.0061 0.0178 0.1297
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0062 0.0447
Schistosoma mansoni pyruvate kinase 0.0019 0.0009 0.0009
Echinococcus granulosus transcription factor Dp 1 0.016 0.0577 0.0642
Entamoeba histolytica exodeoxyribonuclease III, putative 0.006 0.0175 0.0352
Loa Loa (eye worm) jmjC domain-containing protein 0.0126 0.044 0.1272
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0061 0.0176 0.1279
Loa Loa (eye worm) hypothetical protein 0.0079 0.0252 0.0729
Trichomonas vaginalis chromobox protein, putative 0.015 0.0534 0.1005
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0198 0.0728 0.1371
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0031 0.0059
Echinococcus multilocularis geminin 0.0537 0.2091 0.2324
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0878 0.3457 1
Entamoeba histolytica ubiquitin like protein 0.0064 0.0191 0.0385
Loa Loa (eye worm) phosphofructokinase 0.0233 0.0868 0.2511
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0028 0.0047 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0031 0.0059
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0085 0.0274 0.1998
Echinococcus granulosus intermediate filament protein 0.0058 0.0165 0.0184
Loa Loa (eye worm) matrix metalloproteinase 0.0018 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0137
Echinococcus granulosus ecdysone induced protein 78C 0.0028 0.0047 0.0053
Entamoeba histolytica phosphoglycerate kinase, putative 0.0357 0.1366 0.2766
Entamoeba histolytica phosphofructokinase, putative 0.0233 0.0868 0.1756
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0016
Brugia malayi ImpB/MucB/SamB family protein 0.0128 0.0448 0.1293
Mycobacterium leprae Probable pyruvate kinase PykA 0.0037 0.0081 0.0107
Mycobacterium leprae POSSIBLE PENICILLIN-BINDING LIPOPROTEIN 0.0803 0.316 0.5624
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0277 0.1046 0.1163
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.009
Echinococcus multilocularis 6 phosphofructokinase 0.0233 0.0868 0.0965
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0022 0.0021 0.0058
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0126 0.0438 0.3201
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0264 0.0293
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0264 0.0293
Echinococcus multilocularis phosphoglycerate kinase 1 0.0357 0.1366 0.1519
Mycobacterium tuberculosis Conserved protein 0.0079 0.0252 0.0441
Loa Loa (eye worm) hypothetical protein 0.0058 0.0165 0.0479
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0018 0.0005 0.0012
Echinococcus multilocularis Small ubiquitin modifier 2 0.0064 0.0191 0.0213
Trypanosoma cruzi small ubiquitin protein, putative 0.0064 0.0191 0.14
Loa Loa (eye worm) hypothetical protein 0.0027 0.0041 0.0118
Echinococcus granulosus geminin 0.0537 0.2091 0.2324
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0175 0.033
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0252 0.0475
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0081 0.0153
Trypanosoma brucei DNA polymerase kappa, putative 0.0123 0.0428 0.3133
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.002 0.0012 0.0079
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0028 0.0047 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0028 0.0047 0.0133
Brugia malayi beta-NAC-like protein 0.0072 0.0223 0.064
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0031 0.0218
Trypanosoma cruzi small ubiquitin protein, putative 0.0064 0.0191 0.14
Leishmania major small ubiquitin protein, putative 0.0064 0.0191 0.14
Echinococcus granulosus beta LACTamase domain containing family member 0.0079 0.0252 0.028
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.0047 0.0133
Brugia malayi Ubiquitin-like protein SMT3 0.0064 0.0191 0.0549
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.009
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0026 0.0027
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0277 0.1046 0.2117
Leishmania major hypothetical protein, conserved 0.0061 0.0178 0.1303
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0012 0.0035
Echinococcus multilocularis pyruvate kinase 0.0029 0.005 0.0056
Schistosoma mansoni hypothetical protein 0.0026 0.0036 0.0038
Schistosoma mansoni phosphatidylserine receptor 0.002 0.0012 0.0012
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0031 0.0033
Mycobacterium ulcerans beta-lactamase 0.0079 0.0252 0.0279
Trypanosoma cruzi hypothetical protein, conserved 0.0061 0.0178 0.1303
Mycobacterium ulcerans 6-phosphofructokinase 0.0233 0.0868 0.0964
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0028 0.0047 0.0137
Entamoeba histolytica hypothetical protein 0.0023 0.0023 0.0044
Schistosoma mansoni retinoic acid receptor RXR 0.0028 0.0047 0.0051
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0063 0.0186 0.0376
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0016
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0023 0.0031
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0012 0.0014
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0277 0.1046 0.1161
Echinococcus granulosus chromobox protein 1 0.015 0.0534 0.0593
Echinococcus granulosus 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 0.0019 0.001 0.0011
Mycobacterium tuberculosis Probable bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 (murein polymerase) [includes: penicillin-insen 0.1085 0.429 0.7656
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0137
Onchocerca volvulus 0.0024 0.0031 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0023 0.0044
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0264 0.076
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0081 0.0596
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0198 0.0728 0.1473
Loa Loa (eye worm) hypothetical protein 0.0061 0.0178 0.0516
Trypanosoma brucei DNA polymerase eta, putative 0.0183 0.0668 0.4888
Schistosoma mansoni hypothetical protein 0.0032 0.0062 0.0067
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0029 0.0048 0.0354
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0017 0.0001 0.0003
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0198 0.0728 0.0808
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0024 0.0031 0.0218
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0024 0.0031 0.0035
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0198 0.0728 0.2106
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0045 0.005
Schistosoma mansoni lamin 0.0058 0.0165 0.0182
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0011 0.0013
Mycobacterium ulcerans bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 0.1085 0.429 0.4771
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0061 0.0178 0.1303
Leishmania major DNA polymerase eta, putative 0.0095 0.0312 0.2287
Entamoeba histolytica phosphofructokinase, putative 0.0233 0.0868 0.1756
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0063 0.0186 0.1349
Mycobacterium tuberculosis Probable hydrolase 0.0079 0.0252 0.0441
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0181 0.0661 0.1909
Trypanosoma brucei pyruvate kinase 1, putative 0.0037 0.0081 0.0596
Entamoeba histolytica recQ family helicase, putative 0.0035 0.0075 0.0148
Mycobacterium ulcerans hypothetical protein 0.0079 0.0252 0.0279
Mycobacterium leprae Probable NAD-dependent deacetylase NpdA (Regulatory protein SIR2 homolog) 0.0036 0.0079 0.0104
Loa Loa (eye worm) transcriptional regulator 0.0017 0.0001 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.015 0.0537 0.0595
Loa Loa (eye worm) hypothetical protein 0.0126 0.0438 0.1268
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0063 0.0186 0.018
Giardia lamblia DINP protein human, muc B family 0.0149 0.0531 0.1076
Onchocerca volvulus 0.0019 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0079 0.0252 0.0729
Echinococcus multilocularis pyruvate kinase 0.0019 0.0009 0.001
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0047 0.0133
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0018 0.0006 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0252 0.1845
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0032 0.0062 0.0447
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.023 0.0254
Onchocerca volvulus 0.0058 0.0165 0.0406
Plasmodium vivax thioredoxin reductase, putative 0.0052 0.0142 0.1033
Loa Loa (eye worm) hypothetical protein 0.0032 0.0062 0.0181
Schistosoma mansoni protein phosphatase 2C 0.002 0.0012 0.0012
Schistosoma mansoni phd/f-box containing protein 0.002 0.0012 0.0012
Brugia malayi chromobox protein homolog 3 0.0084 0.027 0.0776
Leishmania major ATP-dependent phosphofructokinase 0.0233 0.0868 0.6353
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0022 0.0021 0.0061
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.009
Schistosoma mansoni chromobox protein 0.015 0.0534 0.0592
Brugia malayi nuclear hormone receptor 0.0028 0.0047 0.0133
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0252 0.0475
Brugia malayi nuclear receptor NHR-88 0.0028 0.0047 0.0133
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0028 0.0047 0.0053
Trichomonas vaginalis chromobox protein, putative 0.009 0.0295 0.0556
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0022 0.0021 0.0023
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.006 0.0175 0.0303
Mycobacterium tuberculosis Probable lipase LipD 0.0079 0.0252 0.0441
Mycobacterium tuberculosis Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic 0.0296 0.1123 0.1997
Brugia malayi Steroid receptor seven-up type 2 0.0028 0.0047 0.0133
Giardia lamblia DNA damage repair protein 0.004 0.0093 0.0188
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0609 0.2377 0.4221
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0022 0.0021 0.0144
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0031 0.0218
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0017 0.0001 0.0002
Plasmodium falciparum thioredoxin reductase 0.0052 0.0142 0.1033
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0006 0.0041
Echinococcus multilocularis JmjC domain containing protein 4 0.002 0.0012 0.0014
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0079 0.0252 0.0441
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0783 0.5734
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0018 0.0006 0.0005
Brugia malayi Heterochromatin protein 1 0.015 0.0534 0.154
Echinococcus granulosus Small ubiquitin modifier 2 0.0064 0.0191 0.0213
Schistosoma mansoni jumonji domain containing protein 0.002 0.0012 0.0012
Loa Loa (eye worm) 6-phosphofructokinase 0.0233 0.0868 0.2511
Plasmodium vivax DNA repair protein REV1, putative 0.004 0.0093 0.067
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0783 0.5734
Echinococcus granulosus pyruvate kinase 0.0019 0.0009 0.001
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0198 0.0728 0.1371
Trypanosoma brucei phosphoglycerate kinase, putative 0.0131 0.0459 0.336
Brugia malayi hypothetical protein 0.0032 0.0062 0.0175
Trypanosoma brucei phosphoinositide-specific phospholipase C 0.0019 0.001 0.0072
Loa Loa (eye worm) glutaminase 0.0555 0.2162 0.6253
Trypanosoma brucei pyruvate kinase 1 0.0037 0.0081 0.0596
Schistosoma mansoni DNA helicase recq1 0.0032 0.0062 0.0068
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0132 0.0464 0.0794
Schistosoma mansoni rab6-interacting 0.002 0.0011 0.0011
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0063 0.0186 0.1349
Schistosoma mansoni chromobox protein 0.0024 0.0031 0.0033
Giardia lamblia Flap structure-specific endonuclease 0.0029 0.0048 0.0098
Plasmodium vivax glutathione reductase, putative 0.0052 0.0142 0.1033
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0783 0.5734
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.0403 0.0448
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0233 0.0868 0.1541
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0031 0.0059
Echinococcus multilocularis chromobox protein 1 0.015 0.0534 0.0593
Giardia lamblia Sgs1 DNA helicase, putative 0.0032 0.0062 0.0127
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0783 0.5734
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0054 0.0148 0.1082
Onchocerca volvulus 0.0026 0.0036 0.0077
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0028 0.0046 0.0323
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0119 0.0411 0.0724
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0438 0.0486
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0028 0.0047 0.0051
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0031 0.0059
Loa Loa (eye worm) matrixin family protein 0.004 0.0094 0.0272
Mycobacterium ulcerans NAD-dependent deacetylase 0.0054 0.0148 0.0163
Loa Loa (eye worm) heterochromatin protein 1 0.015 0.0534 0.1544
Onchocerca volvulus Alhambra homolog 0.0061 0.0178 0.0439
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0181 0.0661 0.4838
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0277 0.1046 0.1163
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0047 0.0051
Plasmodium vivax small ubiquitin-related modifier, putative 0.0064 0.0191 0.1391
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0006 0.0041
Trypanosoma brucei small ubiquitin-related modifier 0.0064 0.0191 0.14
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0028 0.0047 0.0137
Loa Loa (eye worm) hypothetical protein 0.0079 0.0252 0.0729
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0028 0.0047 0.0053
Brugia malayi Doublecortin family protein 0.002 0.0011 0.0029
Plasmodium vivax phospholipase C-like, putative 0.0018 0.0005 0.0029
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0062 0.0447
Brugia malayi Matrixin family protein 0.0018 0.0006 0.0012
Mycobacterium ulcerans serine/threonine-protein kinase B PknB 0.0176 0.0639 0.0709
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0181 0.0661 0.0734
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0186 0.0349
Echinococcus multilocularis transcription factor btf3 0.0072 0.0223 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0223 0.0419
Leishmania major trypanothione reductase 0.0052 0.0142 0.1043
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1246 0.4936 0.9297
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.006 0.0175 0.0195
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0022 0.0021 0.0057
Schistosoma mansoni hypothetical protein 0.002 0.0011 0.0011
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0181 0.0661 0.1171
Mycobacterium ulcerans hypothetical protein 0.004 0.0093 0.0102
Entamoeba histolytica hypothetical protein 0.0023 0.0026 0.005
Loa Loa (eye worm) RecQ helicase 0.0047 0.0121 0.0351
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0054 0.0148 0.1073
Brugia malayi Pre-SET motif family protein 0.0126 0.0438 0.1264
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0165 0.0479
Echinococcus granulosus JmjC domain containing protein 4 0.002 0.0012 0.0014
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0011 0.0013
Brugia malayi intermediate filament protein 0.0058 0.0165 0.0475
Plasmodium vivax hypothetical protein, conserved 0.002 0.0013 0.0086
Entamoeba histolytica hypothetical protein 0.0024 0.0031 0.006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0031 0.0059
Plasmodium vivax 6-phosphofructokinase, putative 0.0063 0.0186 0.1349
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0032 0.0062 0.0069
Brugia malayi Associated with TFs and helicases family protein 0.0024 0.0031 0.0086
Echinococcus multilocularis 1 phosphatidylinositol 4,5 bisphosphate 0.0019 0.001 0.0011
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0126 0.0438 0.0487
Brugia malayi Phosphoglycerate kinase 0.0357 0.1366 0.395
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0165 0.0475
Echinococcus granulosus dna polymerase kappa 0.0212 0.0783 0.0871
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0061 0.0178 0.0335
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0169 0.0612 0.177
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0017 0.0001 0.0002
Echinococcus granulosus lamin 0.0058 0.0165 0.0184
Schistosoma mansoni DNA polymerase eta 0.0183 0.0668 0.0741
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1246 0.4936 0.9297
Echinococcus granulosus expressed protein 0.0072 0.0221 0.0246
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0022 0.0021 0.0028
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0277 0.1046 0.7656
Echinococcus granulosus Chromo domain 0.0024 0.0031 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0028 0.0047 0.0137
Brugia malayi Variant SH3 domain containing protein 0.0132 0.0463 0.1336
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0079 0.0252 0.0279
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0438 0.0486
Onchocerca volvulus Cell death protein 3 homolog 0.0032 0.0062 0.0143
Brugia malayi polk-prov protein 0.0123 0.0428 0.1235
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0012 0.0014
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0028 0.0047 0.0053
Schistosoma mansoni blooms syndrome DNA helicase 0.003 0.0055 0.006
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0233 0.0868 0.0863
Schistosoma mansoni jumonji domain containing protein 0.0159 0.0572 0.0634
Echinococcus granulosus neuropeptide s receptor 0.0517 0.2009 0.2233
Echinococcus multilocularis neuropeptide receptor A26 0.0517 0.2009 0.2233
Loa Loa (eye worm) steroid hormone receptor 0.0028 0.0047 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0031 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0223 0.0419
Plasmodium vivax flap endonuclease 1, putative 0.0029 0.0048 0.0344
Trypanosoma cruzi DNA polymerase kappa, putative 0.0212 0.0783 0.5734
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0054 0.0148 0.1082
Schistosoma mansoni rab6-interacting 0.002 0.0011 0.0011
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0026 0.018
Brugia malayi beta-lactamase family protein 0.0079 0.0252 0.0725
Brugia malayi follicle stimulating hormone receptor 0.0246 0.092 0.2658
Loa Loa (eye worm) sirtuin 4 0.0017 0.0001 0.0004
Brugia malayi F/Y-rich N-terminus family protein 0.0025 0.0032 0.0088
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0028 0.0047 0.0053
Loa Loa (eye worm) Plcb4 protein 0.0018 0.0005 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0212 0.0783 0.5734
Plasmodium falciparum DNA repair protein REV1, putative 0.004 0.0093 0.067
Plasmodium vivax hypothetical protein, conserved 0.0061 0.0178 0.1297
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0022 0.0021 0.0057
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0357 0.1366 0.2431
Onchocerca volvulus 0.0198 0.0728 0.1834
Onchocerca volvulus Bile acid receptor homolog 0.0028 0.0047 0.0106
Leishmania major silent information regulator 2, putative 0.0017 0.0001 0.0011
Toxoplasma gondii histone deacetylase SIR2 0.0054 0.0148 0.1073
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0137
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0137
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0037 0.0081 0.0136
Plasmodium falciparum glutathione reductase 0.0052 0.0142 0.1033
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0264 0.0292
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0026 0.0027
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0357 0.1366 1
Echinococcus multilocularis chromobox protein 1 0.015 0.0534 0.0593
Echinococcus multilocularis transcription factor Dp 1 0.016 0.0577 0.0642
Schistosoma mansoni phospholipase C beta 0.0018 0.0005 0.0004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0006 0.0041
Brugia malayi jmjC domain containing protein 0.002 0.0012 0.0031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0028 0.0047 0.0137
Loa Loa (eye worm) transcriptional regulator 0.0017 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0137
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0029 0.0048 0.0354
Loa Loa (eye worm) beta-lactamase 0.0079 0.0252 0.0729
Plasmodium falciparum pyruvate kinase 0.0037 0.0081 0.0586
Brugia malayi Matrixin family protein 0.0018 0.0006 0.0012
Mycobacterium ulcerans penicillin-binding membrane protein PbpB 0.2255 0.899 1
Plasmodium falciparum thioredoxin reductase 0.0018 0.0006 0.003
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0028 0.0047 0.0053
Echinococcus granulosus lysine specific demethylase 5A 0.0074 0.023 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0031 0.0059
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0063 0.0186 0.0349
Trypanosoma brucei chrX additional, unordered contigs 0.004 0.0093 0.068
Brugia malayi PHD-finger family protein 0.002 0.0013 0.0034
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0128 0.0448 0.0498
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0277 0.1046 0.7656
Leishmania major pyruvate kinase 0.0037 0.0081 0.0596
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0001 0.0003
Trypanosoma cruzi DNA damage repair protein, putative 0.004 0.0093 0.068
Echinococcus multilocularis FTZ F1 alpha 0.0028 0.0047 0.0053
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0057 0.0166
Plasmodium falciparum flap endonuclease 1 0.0029 0.0048 0.0344
Loa Loa (eye worm) hypothetical protein 0.0084 0.027 0.078
Echinococcus granulosus dna polymerase eta 0.0183 0.0668 0.0742
Schistosoma mansoni hypothetical protein 0.0024 0.0031 0.0033
Schistosoma mansoni chromatin regulatory protein sir2 0.0054 0.0148 0.0163
Brugia malayi jmjC domain containing protein 0.02 0.0737 0.2129
Entamoeba histolytica hypothetical protein 0.0024 0.0031 0.006
Loa Loa (eye worm) hypothetical protein 0.0032 0.0062 0.0179
Brugia malayi Thioredoxin reductase 0.0052 0.0142 0.0408
Leishmania major phosphoglycerate kinase B, cytosolic 0.0357 0.1366 1
Loa Loa (eye worm) hypothetical protein 0.0079 0.0252 0.0729
Trypanosoma cruzi hypothetical protein, conserved 0.0061 0.0178 0.1303
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0026 0.0021
Mycobacterium leprae PROBABLE BIFUNCTIONAL PENICILLIN-BINDING PROTEIN 1A/1B PONA1 (MUREIN POLYMERASE) (PBP1): PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE 0.1339 0.531 0.9476
Echinococcus granulosus RUN 0.002 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.0066 0.0197 0.057
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0171 0.0323
Echinococcus multilocularis thyroid hormone receptor alpha 0.0028 0.0047 0.0053
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0149 0.0531 0.094
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0277 0.1046 0.3023
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0001 0.0003
Mycobacterium ulcerans esterase/lipase LipP 0.0079 0.0252 0.0279
Treponema pallidum exodeoxyribonuclease (exoA) 0.006 0.0175 0.017
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.006 0.0175 0.0193
Plasmodium vivax 6-phosphofructokinase, putative 0.0063 0.0186 0.1349
Loa Loa (eye worm) helicase 0.0024 0.0031 0.009
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.006 0.0175 0.0195
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0093 0.068
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0277 0.1046 0.7656
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0006 0.0041
Brugia malayi PHD-finger family protein 0.0061 0.0178 0.0512
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0017 0.0001 0.0011
Echinococcus granulosus pyruvate kinase 0.0037 0.0081 0.0091
Brugia malayi Pyruvate kinase, muscle isozyme 0.0037 0.0081 0.0231
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0052 0.0142 0.0245
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0171 0.0323
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0026 0.018
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0165 0.0479
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0031 0.0059
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0252 0.0475
Trypanosoma brucei transcription factor BTF3, putative 0.0072 0.0223 0.1629
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0131 0.0459 0.336
Treponema pallidum hypothetical protein 0.0296 0.1123 0.1118
Toxoplasma gondii 6-phosphofructokinase 0.0063 0.0186 0.1349
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0032 0.0062 0.0069
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0013 0.0086
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0006 0.0041
Mycobacterium ulcerans glutaminase 0.0555 0.2162 0.2403
Loa Loa (eye worm) hypothetical protein 0.0085 0.0274 0.0793
Mycobacterium tuberculosis Possible penicillin-binding lipoprotein 0.0803 0.316 0.5636
Onchocerca volvulus Heterochromatin protein 1 homolog 0.009 0.0295 0.0735
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0252 0.1845
Schistosoma mansoni terminal deoxycytidyl transferase 0.0128 0.0448 0.0497
Onchocerca volvulus 0.0999 0.3944 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0149 0.0531 0.3889
Treponema pallidum penicillin-binding protein (pbp-3) 0.2431 0.9696 0.9696
Echinococcus granulosus Chromobox protein 3 0.0024 0.0031 0.0035
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0085 0.0274 0.1998
Brugia malayi Flap endonuclease-1 0.0029 0.0048 0.0136
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0023 0.0002
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0017 0.0001 0.0002
Plasmodium falciparum phosphoglycerate kinase 0.0357 0.1366 1

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 32 ug ml-1 Minimum inhibitory concentration to inhibit 90 to 100% visible growth of Candida albicans ChEMBL. 12565963
MIC (functional) = 32 ug ml-1 Minimum inhibitory concentration to inhibit 90 to 100% visible growth of Candida albicans ChEMBL. 12565963
MIC (functional) > 128 ug ml-1 Minimum inhibitory concentration required to inhibit 90 to 100% visible growth of Candida glabrata ChEMBL. 12565963

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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