Detailed information for compound 268694

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 337.394 | Formula: C15H19N3O4S
  • H donors: 1 H acceptors: 4 LogP: 0.66 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC([C@H]1C(=O)N2C1CC(=C2C(=O)[O-])SCc1n(C)cc[n+]1C)O
  • InChi: 1S/C15H19N3O4S/c1-8(19)12-9-6-10(13(15(21)22)18(9)14(12)20)23-7-11-16(2)4-5-17(11)3/h4-5,8-9,12,19H,6-7H2,1-3H3/t8?,9?,12-/m1/s1
  • InChiKey: HLXHIVSWUJVYOY-SHVIVCPWSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0042 0.0195 0.0195
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.001 0.0012 0.0033
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0008 0.0003 0.0003
Trypanosoma brucei calmodulin, putative 0.0011 0.002 0.0055
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0046 0.0221 0.0353
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0107
Brugia malayi hypothetical protein 0.0039 0.0181 0.0181
Echinococcus multilocularis transient receptor potential cation channel 0.0021 0.0078 0.0092
Echinococcus granulosus calbindin 32 0.0011 0.002 0.0024
Onchocerca volvulus 0.0075 0.0383 0.6135
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.001 0.0012 0.0033
Mycobacterium leprae PROBABLE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE PROTEIN PROA (GPR) (GLUTAMATE-5-SEMIALDEHYDE DEHYDROGENASE) (GLUTAMYL-GAMMA-SEMIALDE 0.001 0.0012 0.031
Toxoplasma gondii aldehyde dehydrogenase 0.0179 0.0981 1
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0021 0.0078 0.0078
Trichomonas vaginalis calmodulin, putative 0.0011 0.002 0.032
Schistosoma mansoni hypothetical protein 0.001 0.0012 0.0012
Brugia malayi mothers against decapentaplegic homolog 3 0.0011 0.0016 0.0016
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0181 0.0216
Brugia malayi HAD-superfamily hydrolase, subfamily IA, variant 1 containing protein 0.0008 0.0003 0.0003
Mycobacterium tuberculosis Possible epoxide hydrolase EphE (epoxide hydratase) (arene-oxide hydratase) 0.0009 0.0006 0.0023
Trichomonas vaginalis calcium binding protein, putative 0.0011 0.002 0.032
Trichomonas vaginalis calmodulin, putative 0.0011 0.002 0.032
Brugia malayi Niemann-Pick C1 protein precursor 0.0108 0.0574 0.0574
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0068 0.1095
Leishmania major hydrolase-like protein,esterase-like protein 0.0009 0.0006 0.0025
Echinococcus granulosus abhydrolase domain containing protein 0.0009 0.0006 0.0007
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0104 0.1672
Onchocerca volvulus 0.0043 0.02 0.3209
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0092 0.0147
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0021 0.0078 0.0092
Mycobacterium tuberculosis Probable amidase AmiB2 (aminohydrolase) 0.0013 0.0027 0.0101
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0104 0.0104
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0237 0.1315 0.21
Schistosoma mansoni ef hand domain family member A2 0.0011 0.002 0.002
Schistosoma mansoni neuronal calcium sensor 0.0011 0.002 0.002
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.001 0.0012 0.0014
Echinococcus multilocularis neuropeptide s receptor 0.0468 0.2638 0.3138
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0021 0.0078 0.0092
Trypanosoma brucei aldehyde dehydrogenase, putative 0.001 0.0012 0.0033
Echinococcus multilocularis centrin 2 0.0011 0.002 0.0024
Onchocerca volvulus 0.0043 0.02 0.3209
Mycobacterium tuberculosis Possible phosphatase 0.0008 0.0003 0.0012
Mycobacterium tuberculosis Possible haloalkane dehalogenase 0.0009 0.0006 0.0023
Trypanosoma brucei hypothetical protein, conserved 0.0008 0.0003 0.0009
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0226 0.036
Entamoeba histolytica haloacid dehalogenase-like hydrolase domain-containing protein 0.0008 0.0003 0.0052
Trichomonas vaginalis calcium binding protein, putative 0.0011 0.002 0.032
Echinococcus multilocularis potassium voltage gated channel protein 0.0021 0.0078 0.0092
Trichomonas vaginalis calmodulin, putative 0.0011 0.002 0.032
Brugia malayi Aldehyde dehydrogenase protein 4 0.001 0.0012 0.0012
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0075 0.0383 0.1425
Echinococcus multilocularis potassium voltage gated channel protein 0.0021 0.0078 0.0092
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0226 0.0268
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Schistosoma mansoni reticulocalbin 0.0011 0.002 0.002
Schistosoma mansoni cpg binding protein 0.0032 0.0138 0.0138
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.001 0.0012 0.0044
Leishmania major calmodulin, putative 0.0011 0.002 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0003 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0017 0.0277
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0075 0.0075
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0021 0.0078 0.0078
Leishmania major serine peptidase, putative,serine peptidase, Clan SC, Family S9D 0.0009 0.0006 0.0025
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0011 0.002 0.0055
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0092 0.0109
Loa Loa (eye worm) hypothetical protein 0.0075 0.0383 0.0612
Schistosoma mansoni voltage-gated ion channel 0.0021 0.0078 0.0078
Echinococcus granulosus short transient receptor potential channel 6 0.0021 0.0078 0.0092
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0075 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0003 0.0052
Schistosoma mansoni family S33 non-peptidase homologue (S33 family) 0.0009 0.0006 0.0006
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0011 0.002 0.002
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0104 0.0388
Mycobacterium ulcerans peptide amidase, GatA 0.0013 0.0027 0.0151
Echinococcus granulosus beta LACTamase domain containing family member 0.0075 0.0383 0.0456
Schistosoma mansoni smad 0.0024 0.0092 0.0092
Trypanosoma cruzi calmodulin, putative 0.0011 0.002 0.0055
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0017 0.0277
Entamoeba histolytica alpha/beta hydrolase domain protein, putative 0.0009 0.0006 0.0099
Schistosoma mansoni hypothetical protein 0.0011 0.002 0.002
Loa Loa (eye worm) amidase 0.0013 0.0027 0.0043
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.001 0.0012 0.0044
Echinococcus multilocularis voltage dependent calcium channel 0.0021 0.0078 0.0092
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0372 0.103
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0021 0.0078 0.0791
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0021 0.0078 0.0078
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Leishmania major hypothetical protein, unknown function 0.0021 0.0078 0.0315
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0021 0.0078 0.0791
Schistosoma mansoni ap endonuclease 0.002 0.0068 0.0068
Mycobacterium ulcerans 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD 0.0009 0.0006 0.0034
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0523 0.0523
Trypanosoma brucei Component of motile flagella 41 0.0011 0.002 0.0055
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0011 0.002 0.0024
Loa Loa (eye worm) hypothetical protein 0.0043 0.02 0.032
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.001 0.0012 0.0048
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0226 0.0268
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.001 0.0012 0.0033
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.001 0.0012 0.0033
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.001
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0075 0.0089
Echinococcus granulosus inositol monophosphatase 1 0.0073 0.0372 0.0443
Leishmania major phospholipase c-like protein 0.0011 0.002 0.0081
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0011 0.002 0.0055
Schistosoma mansoni inositol monophosphatase 0.0073 0.0372 0.0372
Brugia malayi MH2 domain containing protein 0.0349 0.1956 0.1956
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0011 0.002 0.0024
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0021 0.0078 0.0092
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0092 0.0092
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0075 0.0089
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0075 0.0383 0.0383
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0277 0.0442
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0009 0.0006 0.0099
Entamoeba histolytica hypothetical protein 0.0008 0.0003 0.0052
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.001 0.0012 0.0012
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0078 0.0078
Echinococcus multilocularis C type lectin domian containing protein 0.0043 0.02 0.0238
Echinococcus multilocularis smad 0.0024 0.0092 0.0109
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0075 0.0075
Schistosoma mansoni inositol monophosphatase 0.0073 0.0372 0.0372
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0321 0.1781
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.001 0.0012 0.0044
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0021 0.0078 0.0092
Echinococcus granulosus hypothetical protein 0.0021 0.0078 0.0092
Trypanosoma cruzi caltractin, putative 0.0011 0.002 0.0055
Entamoeba histolytica hypothetical protein 0.0009 0.0006 0.0099
Mycobacterium ulcerans lignin peroxidase LipJ 0.0009 0.0006 0.0034
Schistosoma mansoni cpg binding protein 0.003 0.0128 0.0128
Echinococcus multilocularis voltage dependent calcium channel 0.0021 0.0078 0.0092
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0104 0.0388
Echinococcus granulosus calcium activated potassium channel 0.0021 0.0078 0.0092
Loa Loa (eye worm) hypothetical protein 0.0031 0.0134 0.0215
Entamoeba histolytica calmodulin, putative 0.0011 0.002 0.032
Schistosoma mansoni c4b-binding protein beta chain 0.0043 0.02 0.02
Trypanosoma brucei protein I/6 0.0011 0.002 0.0055
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0009 0.0006 0.0099
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0009 0.0006 0.0099
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0179 0.0981 0.1167
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0003 0.0052
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0011 0.0017 0.0277
Mycobacterium leprae POSSIBLE SECRETED PROTEASE 0.0009 0.0006 0.0161
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0021 0.0078 0.0124
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0068 0.0081
Entamoeba histolytica hypothetical protein 0.0039 0.0181 0.2906
Schistosoma mansoni hypothetical protein 0.0175 0.0956 0.0956
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0008 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0013 0.0027 0.011
Chlamydia trachomatis glutamyl-tRNA(Gln) amidotransferase subunit A 0.0013 0.0027 0.3766
Loa Loa (eye worm) hypothetical protein 0.0318 0.1777 0.2838
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0383 0.6135
Echinococcus granulosus betaine aldehyde dehydrogenase 0.001 0.0012 0.0014
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0021 0.0078 0.0092
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0.0017 0.0277
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0064 0.0321 0.1196
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0321 0.0382
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0021 0.0078 0.0078
Echinococcus multilocularis neuropeptide receptor A26 0.0468 0.2638 0.3138
Brugia malayi voltage-dependent calcium channel 0.0021 0.0078 0.0078
Toxoplasma gondii alpha/beta hydrolase, putative 0.0009 0.0006 0.0063
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0061 0.0226
Toxoplasma gondii troponin c, isotype gamma, putative 0.0011 0.002 0.0204
Giardia lamblia ENC6 protein 0.0009 0.0006 0.0902
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0107
Treponema pallidum aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0013 0.0027 0.3756
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0021 0.0078 0.0078
Mycobacterium ulcerans proline iminopeptidase PIP 0.0009 0.0006 0.0034
Loa Loa (eye worm) hypothetical protein 0.0043 0.02 0.032
Leishmania major hypothetical protein, conserved 0.0437 0.2462 1
Schistosoma mansoni transient receptor potential channel 4 0.0021 0.0078 0.0078
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0321 0.1781
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0075 0.0089
Brugia malayi MH1 domain containing protein 0.0013 0.0031 0.0031
Mycobacterium ulcerans epoxide hydrolase EphE 0.0009 0.0006 0.0034
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0021 0.0078 0.0124
Echinococcus granulosus neurocalcin 0.0011 0.002 0.0024
Brugia malayi calcium-binding protein 0.0011 0.002 0.002
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0021 0.0078 0.0078
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0021 0.0078 0.0092
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0021 0.0078 0.0092
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0006 0.0161
Echinococcus multilocularis calpain A 0.0011 0.002 0.0024
Trichomonas vaginalis myosin light chain 1, putative 0.0011 0.002 0.032
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.001 0.0012 0.0048
Leishmania major centrin, putative 0.0011 0.002 0.0081
Plasmodium vivax alpha/beta hydrolase, putative 0.0009 0.0006 0.0161
Onchocerca volvulus 0.0042 0.0195 0.312
Echinococcus granulosus calumenin 0.0011 0.002 0.0024
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0075 0.012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0107
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.001 0.0012 0.0033
Mycobacterium tuberculosis Probable haloalkane dehalogenase 0.0009 0.0006 0.0023
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0128 0.0204
Mycobacterium ulcerans exported protease 0.0009 0.0006 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0006 0.0017
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0092 0.0109
Giardia lamblia Phosphoglycolate phosphatase 0.0008 0.0003 0.0476
Echinococcus granulosus ferritin 0.0008 0.0002 0.0003
Echinococcus multilocularis short transient receptor potential channel 6 0.0021 0.0078 0.0092
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0021 0.0078 0.0092
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0011 0.002 0.032
Schistosoma mansoni calmodulin 0.0011 0.002 0.002
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0006 0.0161
Schistosoma mansoni hypothetical protein 0.0031 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0017 0.0277
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0068 0.1095
Loa Loa (eye worm) hypothetical protein 0.0054 0.0266 0.0425
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0099 0.0523 0.0622
Echinococcus granulosus voltage gated potassium channel 0.0021 0.0078 0.0092
Leishmania major hypothetical protein, conserved 0.0009 0.0006 0.0025
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0021 0.0078 0.0092
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0226 0.0226
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0107
Trypanosoma brucei centrin-3 0.0011 0.002 0.0055
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.001 0.0012 0.0044
Loa Loa (eye worm) hypothetical protein 0.0057 0.0281 0.0448
Toxoplasma gondii hypothetical protein 0.0021 0.0078 0.0791
Loa Loa (eye worm) voltage-gated calcium channel 0.0021 0.0078 0.0124
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0383 0.6135
Echinococcus multilocularis abhydrolase domain containing protein 11 0.0009 0.0006 0.0007
Onchocerca volvulus 0.0011 0.0017 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0221 0.3538
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0021 0.0078 0.0092
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0068 0.0189
Loa Loa (eye worm) programmed cell death protein 6 0.0011 0.002 0.0032
Loa Loa (eye worm) MH2 domain-containing protein 0.0011 0.0016 0.0026
Echinococcus granulosus haloacid dehalogenase hydrolase 0.0008 0.0003 0.0004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0226 0.0226
Toxoplasma gondii melibiase subfamily protein 0.0099 0.0523 0.5325
Mycobacterium ulcerans amidase 0.0013 0.0027 0.0151
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0008 0.0003 0.0052
Schistosoma mansoni smad1 5 8 and 0.0024 0.0092 0.0092
Loa Loa (eye worm) HAD-superfamily hydrolase 0.0008 0.0003 0.0005
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0075 0.0089
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0075 0.0089
Mycobacterium tuberculosis Conserved protein 0.0075 0.0383 0.1425
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0021 0.0078 0.0092
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0009 0.0006 0.0099
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0011 0.0017 0.0048
Treponema pallidum phosphoglycolate phosphatase 0.0008 0.0003 0.0134
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0011 0.002 0.002
Brugia malayi MH2 domain containing protein 0.0024 0.0092 0.0092
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0181 0.0181
Brugia malayi aldehyde dehydrogenase 0.001 0.0012 0.0012
Mycobacterium ulcerans epoxide hydrolase EphA 0.0322 0.1804 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.001
Trypanosoma cruzi calmodulin, putative 0.0011 0.002 0.0055
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0181 0.0216
Onchocerca volvulus 0.0021 0.0078 0.1244
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.0521 0.0521
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0075 0.0089
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Echinococcus granulosus sodium leak channel non selective protein 0.0021 0.0078 0.0092
Loa Loa (eye worm) voltage-gated potassium channel 0.0021 0.0078 0.0124
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.001 0.0012 0.0066
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0011 0.002 0.032
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0104 0.055 0.0654
Loa Loa (eye worm) beta-lactamase 0.0075 0.0383 0.0612
Loa Loa (eye worm) aldehyde dehydrogenase 0.001 0.0012 0.0019
Mycobacterium ulcerans amidase 0.0013 0.0027 0.0151
Schistosoma mansoni 60S ribosomal protein L21 0.0021 0.0078 0.0078
Loa Loa (eye worm) voltage-gated potassium channel 0.0021 0.0078 0.0124
Mycobacterium leprae PROBABLE AMIDASE AMIC (AMINOHYDROLASE) 0.0013 0.0027 0.0709
Mycobacterium leprae PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) 0.0013 0.0027 0.0709
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0383 0.106
Trichomonas vaginalis hydrolase, putative 0.0009 0.0006 0.0099
Mycobacterium tuberculosis Probable NADH dehydrogenase I (chain H) NuoH (NADH-ubiquinone oxidoreductase chain H) 0.0155 0.0845 0.3143
Plasmodium vivax glutamyl-tRNA(Gln) amidotransferase subunit A, putative 0.0013 0.0027 0.0709
Trichomonas vaginalis calmodulin, putative 0.0011 0.002 0.032
Mycobacterium ulcerans hypothetical protein 0.0008 0.0003 0.0018
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0021 0.0078 0.1244
Loa Loa (eye worm) hypothetical protein 0.0075 0.0383 0.0612
Mycobacterium tuberculosis Conserved protein 0.0009 0.0006 0.0023
Trypanosoma brucei caltractin, putative 0.0011 0.002 0.0055
Trypanosoma cruzi amidase, putative 0.0013 0.0027 0.0075
Brugia malayi olfactory channel protein osm-9 0.0022 0.0081 0.0081
Schistosoma mansoni aldehyde dehydrogenase 0.001 0.0012 0.0012
Echinococcus granulosus expressed conserved protein 0.0101 0.0536 0.0638
Schistosoma mansoni transient receptor potential channel 0.0021 0.0078 0.0078
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0075 0.012
Schistosoma mansoni hypothetical protein 0.0031 0.0134 0.0134
Schistosoma mansoni hypothetical protein 0.0067 0.0342 0.0342
Echinococcus multilocularis transient receptor potential cation channel 0.0021 0.0078 0.0092
Trypanosoma cruzi hydrolase-like protein, putative 0.0009 0.0006 0.0017
Brugia malayi MIR domain containing protein 0.0117 0.0624 0.0624
Echinococcus multilocularis ferritin 0.0008 0.0002 0.0003
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0226 0.0226
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0321 0.0382
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0075 0.0089
Loa Loa (eye worm) HAD-superfamily hydrolase 0.0008 0.0003 0.0005
Echinococcus granulosus fatty acid amide hydrolase 1 0.0013 0.0027 0.0032
Trichomonas vaginalis calmodulin, putative 0.0011 0.002 0.032
Mycobacterium tuberculosis Probable exported protease 0.0009 0.0006 0.0023
Brugia malayi MH1 domain containing protein 0.0013 0.0031 0.0031
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0021 0.0078 0.0092
Brugia malayi hypothetical protein 0.0043 0.02 0.02
Entamoeba histolytica calcium-binding protein, putative 0.0011 0.002 0.032
Schistosoma mansoni DNA ligase IV 0.0011 0.0017 0.0017
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Echinococcus granulosus potassium voltage gated channel protein 0.0021 0.0078 0.0092
Onchocerca volvulus Lipase homolog 0.0009 0.0006 0.0099
Schistosoma mansoni Smad4 0.0024 0.0092 0.0092
Brugia malayi CHE-14 protein 0.0046 0.0221 0.0221
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0021 0.0078 0.0078
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0073 0.0372 0.3795
Echinococcus granulosus hyperpolarization activated cyclic 0.0021 0.0078 0.0092
Giardia lamblia Hydrolase, putative 0.0008 0.0003 0.0476
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0017 0.0048
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0011 0.0017 0.0017
Brugia malayi hypothetical protein 0.0021 0.0075 0.0075
Onchocerca volvulus 0.0043 0.02 0.3209
Brugia malayi hydrolase, alpha/beta fold family protein 0.0009 0.0006 0.0006
Echinococcus multilocularis tumor protein p63 0.037 0.2078 0.2472
Mycobacterium ulcerans amidase 0.0013 0.0027 0.0151
Mycobacterium ulcerans epoxide hydrolase EphB 0.0009 0.0006 0.0034
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Brugia malayi EF hand family protein 0.0011 0.002 0.002
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0068 0.0278
Schistosoma mansoni hypothetical protein 0.0031 0.0134 0.0134
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0134 0.0134
Echinococcus multilocularis programmed cell death protein 0.0011 0.002 0.0024
Mycobacterium tuberculosis Probable esterase LipL 0.0075 0.0383 0.1425
Echinococcus multilocularis transient receptor potential gamma protein 0.0021 0.0078 0.0092
Toxoplasma gondii exonuclease III APE 0.002 0.0068 0.0697
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Echinococcus granulosus voltage gated potassium channel 0.0021 0.0078 0.0092
Leishmania major i/6 autoantigen-like protein 0.0011 0.002 0.0081
Schistosoma mansoni mitochondrial solute carrier 0.0011 0.002 0.002
Entamoeba histolytica haloacid dehalogenase-like hydrolase domain-containing protein 0.0008 0.0003 0.0052
Loa Loa (eye worm) hypothetical protein 0.0013 0.0031 0.0049
Echinococcus granulosus sodium channel protein 0.0021 0.0078 0.0092
Entamoeba histolytica hypothetical protein 0.0021 0.0075 0.1202
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Toxoplasma gondii homoserine O-acetyltransferase, putative 0.0009 0.0006 0.0063
Onchocerca volvulus 0.0011 0.002 0.032
Echinococcus multilocularis transient receptor potential cation channel 0.0021 0.0078 0.0092
Trichomonas vaginalis replication factor C large subunit, putative 0.0011 0.0017 0.0277
Echinococcus multilocularis calcium activated potassium channel 0.0021 0.0078 0.0092
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Toxoplasma gondii centrin, putative 0.0011 0.002 0.0204
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Entamoeba histolytica alpha/beta hydrolase fold protein, putative 0.0009 0.0006 0.0099
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0104 0.2725
Echinococcus multilocularis GPCR, family 2 0.0031 0.0134 0.016
Echinococcus granulosus abhydrolase domain containing protein 3 0.0009 0.0006 0.0007
Brugia malayi Cyclic-nucleotide gated cation channel 0.0021 0.0078 0.0078
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0021 0.0078 0.0092
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0021 0.0078 0.0215
Loa Loa (eye worm) hypothetical protein 0.0067 0.0342 0.0546
Echinococcus multilocularis dnaJ subfamily B 0.0429 0.2412 0.2869
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0075 0.0383 0.1425
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0028
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0017 0.0051 0.0189
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0075 0.0075
Schistosoma mansoni transient receptor potential channel 0.0021 0.0078 0.0078
Brugia malayi topoisomerase 0.0011 0.0017 0.0017
Echinococcus multilocularis transient receptor potential cation channel 0.0021 0.0078 0.0092
Brugia malayi MH1 domain containing protein 0.0024 0.0092 0.0092
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0383 0.6135
Giardia lamblia Phosphoglycolate phosphatase 0.0008 0.0003 0.0476
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.001 0.0012 0.0066
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Plasmodium falciparum apical sushi protein 0.0043 0.02 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0009 0.001
Trichomonas vaginalis calmodulin-2, putative 0.0011 0.002 0.032
Mycobacterium tuberculosis Possible haloalkane dehalogenase DhaA (1-chlorohexane halidohydrolase) 0.0009 0.0006 0.0023
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0019
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0075 0.0089
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.001 0.0012 0.019
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0372 0.103
Entamoeba histolytica hypothetical protein 0.0021 0.0075 0.1202
Brugia malayi PXA domain containing protein 0.0021 0.0075 0.0075
Trypanosoma brucei fatty-acid amide hydrolase, putative 0.0013 0.0027 0.0075
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Entamoeba histolytica hypothetical protein 0.0021 0.0075 0.1202
Loa Loa (eye worm) inositol-1 0.0073 0.0372 0.0595
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0075 0.0089
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0006 0.0017
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0008 0.0008
Brugia malayi UPF0017 protein CG3488 0.0009 0.0006 0.0006
Trypanosoma cruzi glycosyl hydrolase, putative 0.0008 0.0003 0.0009
Echinococcus granulosus glutamyl tRNAGln amidotransferase subunit A 0.0013 0.0027 0.0032
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0011 0.002 0.0055
Schistosoma mansoni Smad4 0.0011 0.0016 0.0016
Trichomonas vaginalis calmodulin, putative 0.0011 0.002 0.032
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0075 0.1202
Leishmania major protein kinase, putative 0.0011 0.002 0.0081
Echinococcus multilocularis calmodulin 0.0011 0.002 0.0024
Echinococcus granulosus TRP transient receptor potential channel 0.0021 0.0078 0.0092
Mycobacterium ulcerans esterase/lipase LipP 0.0075 0.0383 0.2123
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0021 0.0078 0.0078
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0021 0.0078 0.0078
Schistosoma mansoni ferritin 0.0008 0.0002 0.0002
Echinococcus granulosus ryanodine receptor 44f 0.1421 0.81 0.9634
Onchocerca volvulus 0.0043 0.02 0.3209
Chlamydia trachomatis DNA ligase 0.0011 0.0017 0.2209
Echinococcus granulosus hyperpolarization activated cyclic 0.0021 0.0078 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0075 0.1202
Loa Loa (eye worm) hypothetical protein 0.0021 0.0075 0.012
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.001 0.0012 0.0066
Mycobacterium ulcerans amidase 0.0013 0.0027 0.0151
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.001 0.0012 0.019
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0383 0.6135
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0104 0.1672
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0068 0.0068
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0108 0.0574 0.9194
Echinococcus multilocularis inositol monophosphatase 1 0.0073 0.0372 0.0443
Leishmania major calcineurin B subunit, putative 0.0011 0.002 0.0081
Brugia malayi hydrolase, alpha/beta fold family protein 0.0009 0.0006 0.0006
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0099 0.0523 0.0622
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0068 0.0254
Loa Loa (eye worm) NADH dehydrogenase subunit 1 0.0042 0.0195 0.0311
Trypanosoma cruzi hydrolase-like protein, putative 0.0009 0.0006 0.0017
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0064 0.0321 0.0321
Trypanosoma cruzi I/6 autoantigen, putative 0.0011 0.002 0.0055
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.001 0.0012 0.0066
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.001 0.0012 0.0014
Mycobacterium tuberculosis Probable oxidoreductase 0.0009 0.0006 0.0023
Brugia malayi Sushi domain 0.0043 0.02 0.02
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0008 0.0003 0.0052
Echinococcus granulosus lysosomal acid lipase:cholesteryl ester 0.0009 0.0006 0.0007
Trypanosoma cruzi centrin-3 0.0011 0.002 0.0055
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0021 0.0078 0.0078
Onchocerca volvulus 0.0054 0.0266 0.4263
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0008 0.0003 0.0052
Onchocerca volvulus 0.0011 0.002 0.032
Brugia malayi beta-lactamase family protein 0.0075 0.0383 0.0383
Onchocerca volvulus 0.0043 0.02 0.3209
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0104 0.0424
Brugia malayi Amidase family protein 0.0013 0.0027 0.0027
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0078 0.0078
Echinococcus multilocularis expressed protein 0.0008 0.0002 0.0003
Loa Loa (eye worm) Smad1 0.0024 0.0092 0.0147
Schistosoma mansoni hypothetical protein 0.0039 0.0181 0.0181
Echinococcus granulosus short transient receptor potential channel 6 0.0022 0.0081 0.0096
Loa Loa (eye worm) MIR domain-containing protein 0.0117 0.0624 0.0997
Toxoplasma gondii EF hand domain-containing protein 0.0011 0.002 0.0204
Onchocerca volvulus 0.0008 0.0003 0.0052
Trichomonas vaginalis mannosyltransferase 1, putative 0.0117 0.0624 1
Loa Loa (eye worm) calmodulin-like protein 0.0011 0.002 0.0032
Entamoeba histolytica grainin 2 0.0011 0.002 0.032
Schistosoma mansoni hypothetical protein 0.0429 0.2412 0.2412
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0134 0.016
Echinococcus granulosus c4b binding protein beta chain 0.0043 0.02 0.0238
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0134 0.016
Schistosoma mansoni centrin-related 0.0011 0.002 0.002
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0009 0.0006 0.0099
Toxoplasma gondii ABC1 family protein 0.0075 0.0383 0.3903
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0021 0.0078 0.0092
Schistosoma mansoni fatty-acid amide hydrolase 0.0013 0.0027 0.0027
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0075 0.0383 0.1425
Brugia malayi follicle stimulating hormone receptor 0.0237 0.1315 0.1315
Loa Loa (eye worm) HAD-superfamily hydrolase 0.0008 0.0003 0.0005
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0021 0.0078 0.0078
Echinococcus multilocularis expressed conserved protein 0.0101 0.0536 0.0638
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0011 0.002 0.032
Mycobacterium ulcerans hydrolase 0.0009 0.0006 0.0034
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0006 0.0161
Echinococcus multilocularis ryanodine receptor 44f 0.11 0.6262 0.7449
Schistosoma mansoni amidase 0.0104 0.055 0.055
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0075 0.0075
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0009 0.0006 0.0099
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0075 0.0089
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0011 0.0017 0.0277
Schistosoma mansoni neuronal calcium sensor 0.0011 0.002 0.002
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0008 0.0003 0.0052
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0019
Loa Loa (eye worm) amidase 0.0013 0.0027 0.0043
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0104 0.0104
Onchocerca volvulus 0.0075 0.0383 0.6135
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0075 0.0089
Trichomonas vaginalis inositol monophosphatase, putative 0.0073 0.0372 0.5965
Loa Loa (eye worm) hypothetical protein 0.0066 0.0334 0.0533
Loa Loa (eye worm) hypothetical protein 0.0021 0.0075 0.012
Mycobacterium ulcerans bacterioferritin BfrA 0.0008 0.0002 0.0013
Plasmodium vivax haloacid dehalogenase-like hydrolase, putative 0.0008 0.0003 0.0085
Trypanosoma brucei mitochondrial calcium uptake 1 0.0011 0.002 0.0055
Loa Loa (eye worm) hypothetical protein 0.11 0.6262 1
Schistosoma mansoni neuronal calcium sensor 0.0011 0.002 0.002
Plasmodium falciparum acid cluster protein 33 homologue, putative 0.0009 0.0006 0.0308
Schistosoma mansoni hypothetical protein 0.0045 0.0211 0.0211
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0068 0.0109
Loa Loa (eye worm) hypothetical protein 0.0026 0.0104 0.0167
Loa Loa (eye worm) hypothetical protein 0.0046 0.0221 0.0353
Echinococcus granulosus EF hand domain containing family member A2 0.0011 0.002 0.0024
Trichomonas vaginalis calcium binding protein, putative 0.0011 0.002 0.032
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.001 0.0012 0.0033
Leishmania major hypothetical protein, conserved 0.0011 0.002 0.0081
Brugia malayi Hypothetical 54.7 kDa protein F37A4.1 in chromosome III 0.0009 0.0006 0.0006
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.001 0.0012 0.0033
Echinococcus granulosus dnaJ subfamily B 0.0429 0.2412 0.2869
Schistosoma mansoni cpg binding protein 0.0032 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0032
Schistosoma mansoni neuronal calcium sensor 0.0011 0.002 0.002
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.001 0.0012 0.0014
Treponema pallidum phosphoglycolate phosphatase 0.0008 0.0003 0.0134
Onchocerca volvulus 0.0043 0.02 0.3209
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0011 0.002 0.002
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0021 0.0078 0.0078
Echinococcus multilocularis beta LACTamase domain containing family member 0.0075 0.0383 0.0456
Mycobacterium ulcerans aldehyde dehydrogenase 0.001 0.0012 0.0066
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0021 0.0078 0.0078
Leishmania major centrin, putative 0.0011 0.002 0.0081
Echinococcus multilocularis stromal cell derived factor 2 0.0117 0.0624 0.0743
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0321 0.0321
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0012 0.0068
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0075 0.012
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0021 0.0078 0.0124
Schistosoma mansoni aldehyde dehydrogenase 0.0179 0.0981 0.0981
Echinococcus multilocularis calbindin 32 0.0011 0.002 0.0024
Trichomonas vaginalis calmodulin, putative 0.0011 0.002 0.032
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0075 0.0075
Schistosoma mansoni aldehyde dehydrogenase 0.001 0.0012 0.0012
Mycobacterium ulcerans aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0013 0.0027 0.0151
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0021 0.0078 0.0078
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Schistosoma mansoni Smad4 0.0011 0.0016 0.0016
Onchocerca volvulus 0.0008 0.0003 0.0052
Schistosoma mansoni chromosome transmission fidelity factor 0.0011 0.0017 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0075 0.1202
Echinococcus multilocularis programmed cell death protein 0.0011 0.002 0.0024
Plasmodium vivax centrin-1, putative 0.0011 0.002 0.0522
Mycobacterium tuberculosis Conserved protein 0.0075 0.0383 0.1425
Brugia malayi alpha/beta hydrolase 0.0009 0.0006 0.0006
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0383 0.0383
Echinococcus multilocularis sterol regulatory element binding protein 0.0046 0.0221 0.0263
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0021 0.0078 0.0092
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0075 0.0089
Loa Loa (eye worm) MH2 domain-containing protein 0.0349 0.1956 0.3124
Brugia malayi MH1 domain containing protein 0.0024 0.0092 0.0092
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0179 0.0981 0.3986
Echinococcus multilocularis EF hand domain containing family member A2 0.0011 0.002 0.0024
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0028
Echinococcus multilocularis potassium voltage gated channel protein 0.0021 0.0078 0.0092
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0009 0.0014
Echinococcus granulosus mothers against decapentaplegic 2 0.0011 0.0016 0.0019
Echinococcus multilocularis transient receptor potential cation channel 0.0022 0.0081 0.0096
Echinococcus granulosus smad 0.0024 0.0092 0.0109
Echinococcus multilocularis cpg binding protein 0.0032 0.0138 0.0164
Trypanosoma brucei centrin, putative 0.0011 0.002 0.0055
Schistosoma mansoni ferritin 0.0008 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0075 0.1202
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0014 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0028
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.001 0.0012 0.0033
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0226 0.0226
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0075 0.0089
Schistosoma mansoni hypothetical protein 0.0045 0.0211 0.0211
Echinococcus granulosus EF hand domain containing family member A2 0.0011 0.002 0.0024
Mycobacterium ulcerans hypothetical protein 0.0009 0.0006 0.0034
Loa Loa (eye worm) hypothetical protein 0.0021 0.0075 0.012
Loa Loa (eye worm) hypothetical protein 0.0099 0.0521 0.0832
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0134 0.0215
Mycobacterium ulcerans haloalkane dehalogenase 0.0009 0.0006 0.0034
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0092 0.0147
Brugia malayi cation channel family protein 0.0021 0.0078 0.0078
Schistosoma mansoni ferritin 0.0008 0.0002 0.0002
Mycobacterium tuberculosis Conserved protein 0.0075 0.0383 0.1425
Echinococcus granulosus neuropeptide receptor A26 0.0468 0.2638 0.3138
Mycobacterium ulcerans formate hydrogenlyase HycD 0.0042 0.0195 0.108
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0533 0.3008 0.3008
Leishmania major centrin, putative,caltractin, putative 0.0011 0.002 0.0081
Schistosoma mansoni aldehyde dehydrogenase 0.0179 0.0981 0.0981
Echinococcus granulosus calpain A 0.0011 0.002 0.0024
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0061 0.0226
Onchocerca volvulus 0.0015 0.0044 0.0701
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Brugia malayi CXXC zinc finger family protein 0.003 0.0128 0.0128
Brugia malayi Amidase family protein 0.0013 0.0027 0.0027
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0065 0.0329 0.8582
Schistosoma mansoni hypothetical protein 0.0045 0.0211 0.0211
Echinococcus multilocularis short transient receptor potential channel 6 0.0022 0.0081 0.0096
Mycobacterium ulcerans hydrolase 0.0008 0.0003 0.0018
Echinococcus multilocularis haloacid dehalogenase hydrolase 0.0008 0.0003 0.0004
Entamoeba histolytica hypothetical protein 0.0039 0.0181 0.2906
Entamoeba histolytica MIR domain protein 0.0117 0.0624 1
Schistosoma mansoni voltage-gated cation channel 0.0021 0.0078 0.0078
Mycobacterium ulcerans aldehyde dehydrogenase 0.0179 0.0981 0.544
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0021 0.0078 0.0078
Schistosoma mansoni aldehyde dehydrogenase 0.001 0.0012 0.0012
Echinococcus multilocularis muscleblind protein 0.0144 0.0783 0.0931
Brugia malayi ion channel NompC 0.0021 0.0078 0.0078
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0011 0.002 0.0024
Schistosoma mansoni ap endonuclease 0.002 0.0068 0.0068
Echinococcus multilocularis EF hand domain containing family member A2 0.0011 0.002 0.0024
Echinococcus granulosus programmed cell death protein 0.0011 0.002 0.0024
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0075 0.0075
Mycobacterium tuberculosis Probable lipase LipD 0.0075 0.0383 0.1425
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Onchocerca volvulus 0.0042 0.0195 0.312
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0011 0.002 0.0522
Echinococcus granulosus geminin 0.0175 0.0956 0.1137
Loa Loa (eye worm) hypothetical protein 0.0026 0.0104 0.0167
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0075 0.0383 0.2123
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.001 0.0012 0.0044
Loa Loa (eye worm) hypothetical protein 0.0021 0.0075 0.012
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0061 0.0226
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0075 0.0075
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0075 0.0075
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.001 0.0012 0.0121
Loa Loa (eye worm) ryanodine receptor 0.0411 0.2312 0.3692
Brugia malayi DKFZp564C0469 protein 0.0011 0.0017 0.0017
Trypanosoma brucei centrin, putative 0.0011 0.002 0.0055
Mycobacterium ulcerans oxidoreductase 0.0009 0.0006 0.0034
Loa Loa (eye worm) hypothetical protein 0.0043 0.02 0.032
Entamoeba histolytica calcium binding family protein 0.0011 0.002 0.032
Schistosoma mansoni hydrolase 0.0009 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0075 0.0383 0.0612
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0021 0.0078 0.0078
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0021 0.0078 0.0092
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0144 0.0783 0.125
Echinococcus multilocularis calumenin 0.0011 0.002 0.0024
Leishmania major hydrolase, alpha/beta fold family-like protein 0.0009 0.0006 0.0025
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.001 0.0012 0.0033
Plasmodium falciparum replication factor C subunit 1, putative 0.0011 0.0017 0.0862
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0372 0.103
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0021 0.0078 0.0092
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0011 0.0017 0.0451
Onchocerca volvulus 0.0043 0.02 0.3209
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0068 0.0379
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0075 0.0075
Mycobacterium ulcerans bacterioferritin BfrB 0.0008 0.0002 0.0013
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0372 0.1513
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0011 0.002 0.0055
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0065 0.0329 0.1223
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0092 0.0109
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.001 0.0012 0.0014
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Mycobacterium tuberculosis Possible amidase (aminohydrolase) 0.0013 0.0027 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0003 0.0052
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0021 0.0078 0.0092
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0075 0.0383 0.0612
Entamoeba histolytica hypothetical protein 0.0011 0.0017 0.0277
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0078 0.1244
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0021 0.0078 0.0092
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.001 0.0012 0.0033
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0008 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Mycobacterium leprae PROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDENT 0.001 0.0012 0.031
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0068 0.1095
Onchocerca volvulus 0.0075 0.0383 0.6135
Schistosoma mansoni ferritin light chain 0.0008 0.0002 0.0002
Loa Loa (eye worm) abhydrolase domain-containing protein 2 0.0009 0.0006 0.001
Echinococcus granulosus calmodulin 0.0011 0.002 0.0024
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0889 0.505 0.6007
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0075 0.0089
Schistosoma mansoni transient receptor potential channel 0.0022 0.0081 0.0081
Loa Loa (eye worm) voltage-dependent calcium channel 0.0021 0.0078 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0017 0.0277
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0021 0.0078 0.0092
Brugia malayi hypothetical protein 0.0043 0.02 0.02
Brugia malayi Transient-receptor-potential like protein 0.0021 0.0078 0.0078
Echinococcus granulosus transient receptor potential cation channel 0.0022 0.0081 0.0096
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.001 0.0012 0.0033
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0017 0.0051 0.1325
Loa Loa (eye worm) nuclear factor I 0.0013 0.0031 0.0049
Echinococcus granulosus replication factor c subunit 1 0.0011 0.0017 0.0021
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.001 0.0012 0.0066
Schistosoma mansoni calcium-activated potassium channel 0.0021 0.0078 0.0078
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0021 0.0078 0.0078
Echinococcus multilocularis protein dispatched 1 0.0053 0.0258 0.0307
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0523 0.0523
Schistosoma mansoni apoferritin-2 0.0008 0.0002 0.0002
Echinococcus granulosus EF HAND 1 calcium binding site 0.0011 0.002 0.0024
Echinococcus granulosus tumor protein p63 0.037 0.2078 0.2472
Entamoeba histolytica hypothetical protein 0.0008 0.0003 0.0052
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.001 0.0012 0.0014
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0134 0.016
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.0372 0.5965
Echinococcus multilocularis transfer RNA-Gly 0.0021 0.0078 0.0092
Trypanosoma cruzi FHA domain containing protein, putative 0.0011 0.0017 0.0048
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0104 0.0579
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0068 1
Trypanosoma cruzi amidase, putative 0.0013 0.0027 0.0075
Schistosoma mansoni centrin 0.0011 0.002 0.002
Echinococcus granulosus calcium uptake protein 1 0.0011 0.002 0.0024
Echinococcus multilocularis abhydrolase domain containing protein 16A 0.0009 0.0006 0.0007
Mycobacterium ulcerans homoserine O-acetyltransferase 0.0009 0.0006 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0003 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.002 0.032
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0068 0.0809
Brugia malayi MH2 domain containing protein 0.0024 0.0092 0.0092
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0067 0.0248
Mycobacterium ulcerans lipase/esterase 0.0009 0.0006 0.0034
Echinococcus multilocularis potassium large conductance calcium activated 0.0021 0.0078 0.0092
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0104 0.0104
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0013 0.0027 0.0032
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0021 0.0078 0.0078
Mycobacterium tuberculosis Probable homoserine O-acetyltransferase MetA (homoserine O-trans-acetylase) (homoserine transacetylase) (HTA) 0.0009 0.0006 0.0023
Brugia malayi NADH dehydrogenase subunit 1 0.0042 0.0195 0.0195
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0092 0.0109
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0066 0.0334 0.5344
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Loa Loa (eye worm) HAD-superfamily hydrolase 0.0008 0.0003 0.0005
Brugia malayi NADH dehydrogenase subunit 1, identical 0.0042 0.0195 0.0195
Echinococcus multilocularis haloacid dehalogenase hydrolase 0.0008 0.0003 0.0004
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0008 0.0003 0.0003
Schistosoma mansoni voltage-dependent calcium channel 0.0021 0.0078 0.0078
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0021 0.0078 0.0092
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0075 0.0089
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0078 0.0078
Brugia malayi hypothetical protein 0.0011 0.0017 0.0017
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0043 0.02 0.032
Brugia malayi Smad1 0.0024 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0049 0.0237 0.0378
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0017 0.0277
Echinococcus granulosus mothers against decapentaplegic 6 0.0011 0.0016 0.0019
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0021 0.0078 0.0078
Leishmania major aldehyde dehydrogenase, putative 0.001 0.0012 0.0048
Leishmania major aldehyde dehydrogenase, putative 0.001 0.0012 0.0048
Schistosoma mansoni glutamyl-tRNA(Gln) amidotransferase subunit A 0.0013 0.0027 0.0027
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.001 0.0012 0.0012
Giardia lamblia Replication factor C, subunit 1 0.0011 0.0017 0.2527
Brugia malayi amidase 0.0104 0.055 0.055
Schistosoma mansoni aldehyde dehydrogenase 0.001 0.0012 0.0012
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0134 0.016
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0021 0.0078 0.0078
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0021 0.0078 0.0092
Mycobacterium ulcerans hypothetical protein 0.0026 0.0104 0.0579
Loa Loa (eye worm) hypothetical protein 0.0043 0.02 0.032
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0003 0.0052
Brugia malayi Pax transcription activation domain interacting protein 0.0011 0.0017 0.0017
Echinococcus granulosus two pore calcium channel protein 1 0.0021 0.0078 0.0092
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.001 0.0012 0.0019
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0322 0.1804 0.6712
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0383 0.0383
Mycobacterium ulcerans non-heme haloperoxidase Hpx 0.0009 0.0006 0.0034
Onchocerca volvulus 0.0117 0.0624 1
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0021 0.0078 0.0092
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0099 0.0523 0.0622
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.001 0.0012 0.0066
Brugia malayi pregnancy-associated plasma protein-A 0.0043 0.02 0.02
Brugia malayi beta-lactamase family protein 0.0075 0.0383 0.0383
Mycobacterium ulcerans exported protease 0.0009 0.0006 0.0034
Schistosoma mansoni smad 0.0011 0.0016 0.0016
Schistosoma mansoni aldehyde dehydrogenase 0.001 0.0012 0.0012
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Onchocerca volvulus 0.0026 0.0104 0.1672
Plasmodium falciparum glutamyl-tRNA(Gln) amidotransferase subunit A 0.0013 0.0027 0.1355
Echinococcus granulosus voltage gated hydrogen channel 1 0.0021 0.0078 0.0092
Toxoplasma gondii transporter, cation channel family protein 0.0021 0.0078 0.0791
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0011 0.002 0.0024
Brugia malayi hypothetical protein 0.0021 0.0075 0.0075
Schistosoma mansoni calmodulin 0.0011 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0048 0.0228 0.0364
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0075 0.0075
Echinococcus granulosus transient receptor potential gamma protein 0.0021 0.0078 0.0092
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0334 0.0334
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0523 0.0523
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Onchocerca volvulus Epoxide hydrolase 1 homolog 0.0009 0.0006 0.0099
Toxoplasma gondii transporter, cation channel family protein 0.0021 0.0078 0.0791
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0006 0.0017
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.001 0.0012 0.0121
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0021 0.0078 0.0092
Mycobacterium ulcerans lipase LipD 0.0075 0.0383 0.2123
Echinococcus multilocularis muscleblind protein 1 0.0144 0.0783 0.0931
Leishmania major hydrolase-like protein 0.0009 0.0006 0.0025
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0342 0.0342
Echinococcus granulosus nibrin 0.0011 0.0017 0.0021
Echinococcus granulosus potassium voltage gated channel protein 0.0021 0.0078 0.0092
Brugia malayi hypothetical protein 0.0021 0.0078 0.0078
Leishmania major hydrolase-like protein,esterase-like protein 0.0009 0.0006 0.0025
Loa Loa (eye worm) hypothetical protein 0.0043 0.02 0.032
Schistosoma mansoni smad1 5 8 and 0.0024 0.0092 0.0092
Echinococcus granulosus sterol regulatory element binding protein 0.0046 0.0221 0.0263
Echinococcus granulosus C type lectin domian containing protein 0.0043 0.02 0.0238
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.0521 0.0521
Trypanosoma cruzi I/6 autoantigen, putative 0.0011 0.002 0.0055
Loa Loa (eye worm) MH1 domain-containing protein 0.0011 0.0016 0.0026
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0066 0.0334 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0075 0.1202
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0011 0.002 0.0055
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0075 0.0089
Plasmodium vivax apical sushi protein, putative 0.0043 0.02 0.5231
Echinococcus granulosus shaker cognate 0.0021 0.0078 0.0092
Echinococcus multilocularis abhydrolase domain containing protein 0.0009 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0032
Plasmodium falciparum alpha/beta hydrolase, putative 0.0009 0.0006 0.0308
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Mycobacterium tuberculosis Probable amidase AmiC (aminohydrolase) 0.0013 0.0027 0.0101
Entamoeba histolytica calmodulin, putative 0.0011 0.002 0.032
Echinococcus multilocularis abhydrolase domain containing protein 3 0.0009 0.0006 0.0007
Schistosoma mansoni ryanodine receptor 1 skeletal muscle 0.0201 0.1108 0.1108
Leishmania major hypothetical protein, conserved 0.0011 0.002 0.0081
Echinococcus granulosus Smad4 0.0024 0.0092 0.0109
Echinococcus granulosus fatty acid amide hydrolase 1 0.0104 0.055 0.0654
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0021 0.0078 0.0092
Loa Loa (eye worm) hypothetical protein 0.0075 0.0383 0.0612
Mycobacterium tuberculosis Protein tyrosine kinase transcriptional regulatory protein PtkA 0.0008 0.0003 0.0012
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.001 0.0012 0.0066
Echinococcus multilocularis mothers against decapentaplegic 2 0.0011 0.0016 0.0019
Echinococcus granulosus transient receptor potential cation channel 0.0021 0.0078 0.0092
Mycobacterium leprae Probable homoserine o-acetyltransferase MetA 0.0009 0.0006 0.0161
Mycobacterium tuberculosis Probable lipase LipE 0.0075 0.0383 0.1425
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0068 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0104 0.0579
Trichomonas vaginalis esterase, putative 0.0075 0.0383 0.6135
Mycobacterium tuberculosis Possible formate hydrogenlyase HycD (FHL) 0.0042 0.0195 0.0725
Brugia malayi MH2 domain containing protein 0.0011 0.0016 0.0016
Toxoplasma gondii rhoptry neck protein RON9 0.0043 0.02 0.2042
Loa Loa (eye worm) hypothetical protein 0.0075 0.0383 0.0612
Echinococcus granulosus transient receptor potential cation channel 0.0021 0.0078 0.0092
Onchocerca volvulus 0.0043 0.02 0.3209
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Plasmodium vivax hypothetical protein, conserved 0.0075 0.0383 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0028
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0179 0.0981 0.1167
Echinococcus multilocularis protein patched 0.0046 0.0221 0.0263
Brugia malayi Inositol-1 0.0073 0.0372 0.0372
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0021 0.0078 0.0092
Trichomonas vaginalis ferritin, putative 0.0008 0.0002 0.0038
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0011 0.002 0.0055
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0075 0.0075
Onchocerca volvulus Lipase homolog 0.0009 0.0006 0.0099
Echinococcus granulosus transient receptor potential cation channel 0.0021 0.0078 0.0092
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0021 0.0078 0.0078
Loa Loa (eye worm) ab-hydrolase associated lipase region family protein 0.0009 0.0006 0.001
Mycobacterium tuberculosis Possible epoxide hydrolase EphF (epoxide hydratase) (arene-oxide hydratase) 0.0009 0.0006 0.0023
Schistosoma mansoni topbp1 0.0011 0.0017 0.0017
Echinococcus granulosus voltage dependent calcium channel 0.0021 0.0078 0.0092
Mycobacterium tuberculosis Probable carboxylesterase CaeA 0.0009 0.0006 0.0023
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0009 0.0006 0.0099
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0075 0.0075
Echinococcus granulosus potassium voltage gated channel protein 0.0021 0.0078 0.0092
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0011 0.002 0.0055
Echinococcus multilocularis potassium voltage gated channel protein 0.0021 0.0078 0.0092
Echinococcus granulosus muscleblind protein 0.0144 0.0783 0.0931
Loa Loa (eye worm) haloacid dehalogenase-like hydrolase 0.0008 0.0003 0.0005
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Brugia malayi cation channel family protein 0.0755 0.4283 0.4283
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Mycobacterium ulcerans aldehyde dehydrogenase 0.0179 0.0981 0.544
Echinococcus granulosus cpg binding protein 0.0032 0.0138 0.0164
Brugia malayi hypothetical protein 0.0043 0.02 0.02
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0008 0.0002 0.0009
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0104 0.0424
Leishmania major hydrolase, alpha/beta fold family, putative 0.0009 0.0006 0.0025
Loa Loa (eye worm) transcription factor SMAD2 0.0349 0.1956 0.3124
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0226 0.0268
Echinococcus granulosus microtubule associated protein 2 0.1475 0.8407 1
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.001 0.0012 0.0066
Echinococcus granulosus NADH dehydrogenase subunit 1 0.0155 0.0845 0.1005
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0011 0.0017 0.0277
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Wolbachia endosymbiont of Brugia malayi bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 0.001 0.0012 0.0141
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Schistosoma mansoni rab 0.0011 0.002 0.002
Echinococcus granulosus voltage dependent calcium channel 0.0021 0.0078 0.0092
Giardia lamblia Hydrolase, haloacid dehalogenase-like family 0.0008 0.0003 0.0476
Loa Loa (eye worm) hypothetical protein 0.0022 0.0081 0.0129
Schistosoma mansoni hypothetical protein 0.0045 0.0211 0.0211
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0104 0.0579
Toxoplasma gondii calmodulin CAM1 0.0011 0.002 0.0204
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0075 0.0075
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0075 0.0089
Mycobacterium ulcerans haloalkane dehalogenase 0.0009 0.0006 0.0034
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0073 0.0372 0.5965
Trypanosoma brucei I/6 autoantigen 0.0011 0.002 0.0055
Mycobacterium ulcerans NADH dehydrogenase subunit H 0.0155 0.0845 0.4682
Treponema pallidum DNA ligase (lig) 0.0011 0.0017 0.2259
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0021 0.0078 0.0092
Echinococcus multilocularis voltage gated potassium channel 0.0021 0.0078 0.0092
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.001 0.0012 0.0066
Echinococcus multilocularis neuronal calcium sensor 0.0011 0.002 0.0024
Echinococcus multilocularis conserved hypothetical protein 0.0021 0.0078 0.0092
Mycobacterium tuberculosis Probable amidase AmiA2 (aminohydrolase) 0.0013 0.0027 0.0101
Brugia malayi hypothetical protein 0.0011 0.0017 0.0017
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0075 0.0075
Mycobacterium ulcerans lipase/esterase 0.0009 0.0006 0.0034
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0282 0.2876
Schistosoma mansoni hypothetical protein 0.0175 0.0956 0.0956
Echinococcus granulosus two pore calcium channel protein 2 0.0021 0.0078 0.0092
Schistosoma mansoni calmodulin related calcium binding protein 0.0011 0.002 0.002
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0104 0.2725
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.0521 0.0832
Giardia lamblia Alcohol dehydrogenase 0.001 0.0012 0.1737
Echinococcus granulosus ryanodine receptor 44f 0.11 0.6262 0.7449
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0104 0.0579
Loa Loa (eye worm) haloacid dehalogenase-like hydrolase 0.0008 0.0003 0.0005
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0075 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.002 0.032
Brugia malayi hypothetical protein 0.0043 0.02 0.02
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0075 0.012
Toxoplasma gondii ATPase, AAA family protein 0.0011 0.0017 0.0176
Mycobacterium tuberculosis Possible peroxidase BpoB (non-haem peroxidase) 0.0009 0.0006 0.0023
Echinococcus multilocularis glutamyl tRNA(Gln) amidotransferase subunit A 0.0013 0.0027 0.0032
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0021 0.0078 0.0092
Echinococcus granulosus centrin 2 0.0011 0.002 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0003 0.0052
Mycobacterium ulcerans peroxidase BpoB 0.0009 0.0006 0.0034
Echinococcus granulosus GPCR family 2 0.0031 0.0134 0.016
Echinococcus granulosus transient receptor potential cation channel 0.0021 0.0078 0.0092
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.001 0.0012 0.0014
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.001 0.0012 0.0121
Trypanosoma brucei hypothetical protein, conserved 0.0011 0.002 0.0055
Mycobacterium ulcerans hypothetical protein 0.0075 0.0383 0.2123
Mycobacterium ulcerans hydrolase 0.0008 0.0003 0.0018
Brugia malayi GCC2 and GCC3 family protein 0.0049 0.0237 0.0237
Wolbachia endosymbiont of Brugia malayi phosphatase 0.0008 0.0003 0.0039
Trypanosoma brucei hydrolase, alpha/beta fold family, putative 0.0009 0.0006 0.0017
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.001 0.0012 0.0012
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0075 0.0075
Echinococcus granulosus fatty acid amide hydrolase 1 0.0104 0.055 0.0654
Mycobacterium ulcerans hypothetical protein 0.0009 0.0006 0.0034
Brugia malayi programmed cell death protein 6 0.0011 0.002 0.002
Mycobacterium ulcerans aldehyde dehydrogenase 0.0179 0.0981 0.544
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.001 0.0012 0.0033
Echinococcus multilocularis sodium channel protein 0.0021 0.0078 0.0092
Echinococcus granulosus transient receptor potential cation channel 0.0021 0.0078 0.0092
Entamoeba histolytica haloacid dehalogenase-like hydrolase domain-containing protein 0.0008 0.0003 0.0052
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0021 0.0078 0.0092
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0068 0.1785
Echinococcus multilocularis lysosomal acid lipase:cholesteryl ester 0.0009 0.0006 0.0007
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0011 0.002 0.032
Schistosoma mansoni stromal cell-derived factor 2 precursor-like protein 0.0117 0.0624 0.0624
Trypanosoma brucei calmodulin, putative 0.0011 0.002 0.0055
Echinococcus multilocularis lysosomal acid lipase:cholesteryl ester 0.0009 0.0006 0.0007
Echinococcus granulosus expressed protein 0.0406 0.2285 0.2718
Trichomonas vaginalis calcium binding proteins, putative 0.0011 0.002 0.032
Schistosoma mansoni hypothetical protein 0.0021 0.0078 0.0078
Trichomonas vaginalis calcium binding protein, putative 0.0011 0.002 0.032
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0061 0.0226
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0477 0.2687 1
Brugia malayi EF hand family protein 0.0011 0.002 0.002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0226 0.0268
Echinococcus multilocularis neurocalcin 0.0011 0.002 0.0024
Echinococcus multilocularis Smad4 0.0024 0.0092 0.0109
Echinococcus multilocularis transient receptor potential cation channel 0.0022 0.0081 0.0096
Leishmania major aldehyde dehydrogenase, putative 0.001 0.0012 0.0048
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0075 0.1202
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0099 0.0523 0.0523
Schistosoma mansoni hypothetical protein 0.0155 0.0845 0.0845
Wolbachia endosymbiont of Brugia malayi aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0013 0.0027 0.0321
Echinococcus multilocularis voltage gated potassium channel 0.0021 0.0078 0.0092
Loa Loa (eye worm) hypothetical protein 0.0144 0.0783 0.125
Schistosoma mansoni hypothetical protein 0.043 0.2418 0.2418
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0134 0.0134
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.001 0.0012 0.0033
Trichomonas vaginalis centrin, putative 0.0011 0.002 0.032
Mycobacterium tuberculosis Probable amidase AmiD (acylamidase) (acylase) 0.0013 0.0027 0.0101
Schistosoma mansoni vesicular amine transporter 0.0021 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0332 0.1856 0.2963
Leishmania major calmodulin, putative 0.0011 0.002 0.0081
Echinococcus granulosus potassium voltage gated channel protein 0.0021 0.0078 0.0092
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0068 0.0189
Schistosoma mansoni apoferritin-2 0.0008 0.0002 0.0002
Wolbachia endosymbiont of Brugia malayi NADH dehydrogenase subunit H 0.0155 0.0845 1
Brugia malayi beta-lactamase 0.0075 0.0383 0.0383
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0021 0.0078 0.0315
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0011 0.0017 0.0048
Echinococcus multilocularis microtubule associated protein 2 0.1475 0.8407 1
Schistosoma mansoni two-pore calcium channel 0.0021 0.0078 0.0078
Mycobacterium leprae POSSIBLE EPOXIDE HYDROLASE EPHE (EPOXIDE HYDRATASE) (ARENE-OXIDE HYDRATASE) 0.0009 0.0006 0.0161
Echinococcus multilocularis ryanodine receptor 44f 0.1421 0.81 0.9634
Echinococcus multilocularis hyperpolarization activated cyclic 0.0021 0.0078 0.0092
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0011 0.002 0.0024
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0008 0.0002 0.0028
Entamoeba histolytica grainin, putative 0.0011 0.002 0.032
Loa Loa (eye worm) hypothetical protein 0.0026 0.0104 0.0167
Echinococcus granulosus neuronal calcium sensor 0.0011 0.002 0.0024
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.001 0.0012 0.0044
Brugia malayi PXA domain containing protein 0.0021 0.0075 0.0075
Mycobacterium tuberculosis Conserved hypothetical protein 0.0008 0.0003 0.0012
Mycobacterium leprae Probable exported protease 0.0009 0.0006 0.0161
Echinococcus multilocularis nibrin 0.0011 0.0017 0.0021
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.0372 0.5965
Loa Loa (eye worm) hypothetical protein 0.0021 0.0075 0.012
Echinococcus granulosus Niemann Pick C1 protein 0.0154 0.0839 0.0998
Trichomonas vaginalis calmodulin, putative 0.0011 0.002 0.032
Echinococcus multilocularis geminin 0.0175 0.0956 0.1137
Mycobacterium ulcerans beta-lactamase 0.0075 0.0383 0.2123
Mycobacterium ulcerans hypothetical protein 0.0009 0.0006 0.0034
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.001 0.0012 0.0066
Schistosoma mansoni ferritin light chain 0.0008 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.001 0.0012 0.019
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0011 0.002 0.002
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0011 0.0017 0.0096
Mycobacterium ulcerans epoxide hydrolase EphF 0.0009 0.0006 0.0034
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0067 1
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0638 0.3615 1
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0021 0.0078 0.0078
Brugia malayi hypothetical protein 0.0043 0.02 0.02
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0067 0.037
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0011 0.002 0.0055
Giardia lamblia Hypothetical protein 0.0011 0.002 0.2926
Echinococcus multilocularis shaker cognate 0.0021 0.0078 0.0092
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0008 0.0003 0.0052
Echinococcus granulosus Niemann Pick C1 protein 0.0108 0.0574 0.0683
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0075 0.0075
Treponema pallidum gamma-glutamyl phosphate reductase 0.001 0.0012 0.1441
Mycobacterium ulcerans amidase 0.0013 0.0027 0.0151
Schistosoma mansoni choline dehydrogenase 0.0008 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0383 0.106
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0104 0.0579
Schistosoma mansoni reticulocalbin 0.0011 0.002 0.002
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0011 0.0017 0.0205
Plasmodium falciparum centrin-1 0.0011 0.002 0.0998
Trypanosoma cruzi calmodulin, putative 0.0011 0.002 0.0055
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0075 0.0089
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0073 0.0372 0.4409
Trypanosoma cruzi hydrolase-like protein 0.0009 0.0006 0.0017
Onchocerca volvulus 0.003 0.0128 0.2049
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0064 0.0321 0.1305
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.001 0.0012 0.0044
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.001 0.0012 0.0066
Echinococcus granulosus abhydrolase domain containing protein 11 0.0009 0.0006 0.0007
Toxoplasma gondii rhoptry neck protein RON1 0.0043 0.02 0.2042
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0067 0.333
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.001 0.0012 0.0033
Loa Loa (eye worm) hypothetical protein 0.0008 0.0003 0.0005
Trypanosoma cruzi centrin, putative 0.0011 0.002 0.0055
Mycobacterium ulcerans bromoperoxidase BpoC 0.0009 0.0006 0.0034
Echinococcus multilocularis Niemann Pick C1 protein 0.0108 0.0574 0.0683
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0179 0.0981 0.3652
Mycobacterium leprae conserved hypothetical protein 0.0075 0.0383 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0104 0.0579
Toxoplasma gondii centrin 0.0011 0.002 0.0204
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Schistosoma mansoni fatty-acid amide hydrolase 0.0104 0.055 0.055
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Mycobacterium tuberculosis Probable hydrolase 0.0075 0.0383 0.1425
Brugia malayi Melibiase family protein 0.0066 0.0334 0.0334
Loa Loa (eye worm) ryanodine receptor 0.0661 0.3744 0.5979
Trichomonas vaginalis calmodulin, putative 0.0011 0.002 0.032
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0104 0.0424
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Echinococcus granulosus haloacid dehalogenase hydrolase 0.0008 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0108 0.0574 0.0917
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0222 0.123 0.123
Echinococcus granulosus Protein patched homolog 1 0.0046 0.0221 0.0263
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0021 0.0078 0.0092
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0064 0.0321 0.0321
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.001 0.0012 0.0014
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.001 0.0012 0.0014
Schistosoma mansoni smad1 5 8 and 0.0024 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0075 0.0383 0.0612
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0107
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.001 0.0012 0.0012
Echinococcus granulosus neuropeptide s receptor 0.0468 0.2638 0.3138
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0.0017 0.0277
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0073 0.0372 0.2065
Schistosoma mansoni niemann-pick C1 (NPC1) 0.011 0.0584 0.0584
Echinococcus granulosus stromal cell derived factor 2 0.0117 0.0624 0.0743
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0008 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0222 0.123 0.1965
Echinococcus multilocularis Niemann Pick C1 protein 0.0154 0.0839 0.0998
Toxoplasma gondii calcium-dependent protein kinase 0.0011 0.002 0.0204
Echinococcus multilocularis c4b binding protein beta chain 0.0043 0.02 0.0238
Plasmodium vivax hypothetical protein, conserved 0.0011 0.002 0.0522
Schistosoma mansoni patched 1 0.0046 0.0221 0.0221
Echinococcus multilocularis calmodulin 0.0011 0.002 0.0024
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0021 0.0078 0.0215
Trichomonas vaginalis calcineurin B subunit, putative 0.0011 0.002 0.032
Loa Loa (eye worm) hypothetical protein 0.0043 0.02 0.032
Leishmania major hypothetical protein, conserved 0.0075 0.0383 0.1556
Onchocerca volvulus 0.0011 0.002 0.032
Schistosoma mansoni NADH dehydrogenase subunit 1 0.0042 0.0195 0.0195
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.001 0.0012 0.0019
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0011 0.0017 0.0176
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0009 0.001
Brugia malayi HAD-superfamily hydrolase, subfamily IA, variant 3 containing protein 0.0008 0.0003 0.0003
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0021 0.0078 0.0092
Echinococcus multilocularis expressed protein 0.0406 0.2285 0.2718
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0068 0.0081
Schistosoma mansoni topbp1 0.0011 0.0017 0.0017
Mycobacterium ulcerans hypothetical protein 0.0008 0.0003 0.0018
Loa Loa (eye worm) ion channel NompC 0.0021 0.0078 0.0124
Plasmodium falciparum haloacid dehalogenase-like hydrolase, putative 0.0008 0.0003 0.0162
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.001 0.0012 0.0044
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0383 0.6135
Brugia malayi putative amidase 0.0013 0.0027 0.0027
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0075 0.0089
Schistosoma mansoni ferritin 0.0008 0.0002 0.0002
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0266 0.0266
Mycobacterium tuberculosis Probable hydrolase 0.0008 0.0003 0.0012
Entamoeba histolytica hypothetical protein 0.0039 0.0181 0.2906
Loa Loa (eye worm) hypothetical protein 0.0043 0.02 0.032
Echinococcus multilocularis hyperpolarization activated cyclic 0.0021 0.0078 0.0092
Trypanosoma cruzi hydrolase, alpha/beta fold family, putative 0.0009 0.0006 0.0017
Echinococcus granulosus potassium large conductance calcium activated 0.0021 0.0078 0.0092
Trypanosoma brucei hypothetical protein, conserved 0.0075 0.0383 0.106
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.001 0.0012 0.0033
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0104 0.1672
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.001 0.0012 0.0066
Brugia malayi Alpha/beta hydrolase 0.0009 0.0006 0.0006
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0008 0.0003 0.0052
Brugia malayi hypothetical protein 0.0043 0.02 0.02
Plasmodium vivax replication factor C subunit 1, putative 0.0011 0.0017 0.0451
Schistosoma mansoni 2-deoxyglucose-6-phosphate phosphatase 0.0008 0.0003 0.0003
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0021 0.0078 0.0092
Mycobacterium ulcerans short chain dehydrogenase 0.0017 0.0051 0.0281
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0021 0.0078 0.0078
Trypanosoma cruzi centrin, putative 0.0011 0.002 0.0055
Toxoplasma gondii hypothetical protein 0.0021 0.0078 0.0791
Leishmania major hypothetical protein, conserved 0.0009 0.0006 0.0025
Schistosoma mansoni ryanodine receptor related 0.1752 1 1
Echinococcus multilocularis two pore calcium channel protein 2 0.0021 0.0078 0.0092
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0075 0.0075
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0068 0.0189
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0008 0.0003 0.0052
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0028
Mycobacterium ulcerans hydrolase 0.0009 0.0006 0.0034
Echinococcus multilocularis sodium leak channel non selective protein 0.0021 0.0078 0.0092
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0021 0.0078 0.0092
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.001 0.0012 0.0044
Brugia malayi Muscleblind-like protein 0.0144 0.0783 0.0783
Toxoplasma gondii transporter, cation channel family protein 0.0021 0.0078 0.0791
Mycobacterium leprae Probable hydrolase 0.0008 0.0003 0.0085
Loa Loa (eye worm) hypothetical protein 0.0104 0.055 0.0878
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0104 0.055 0.0654
Echinococcus granulosus expressed protein 0.0008 0.0002 0.0003
Loa Loa (eye worm) EF hand family protein 0.0011 0.002 0.0032
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0068 0.3412
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0021 0.0078 0.0078
Echinococcus multilocularis mothers against decapentaplegic 6 0.0011 0.0016 0.0019
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0075 0.0075
Brugia malayi Calmodulin-like protein 0.0011 0.002 0.002
Toxoplasma gondii Alpha-galactosidase 0.0014 0.0036 0.0364
Loa Loa (eye worm) hydrolase 0.0009 0.0006 0.001
Entamoeba histolytica hypothetical protein 0.0039 0.0181 0.2906
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0021 0.0078 0.0078
Leishmania major calmodulin-like protein 0.0011 0.002 0.0081
Leishmania major calmodulin-like protein 0.0011 0.002 0.0081
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Trypanosoma brucei hydrolase, alpha/beta fold family, putative 0.0009 0.0006 0.0017
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0011 0.0016 0.0262
Loa Loa (eye worm) hypothetical protein 0.0021 0.0078 0.0124
Trichomonas vaginalis calcineurin B subunit, putative 0.0011 0.002 0.032
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0003 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0075 0.1202
Loa Loa (eye worm) calcium channel 0.0021 0.0078 0.0124
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.001 0.0012 0.0066
Trichomonas vaginalis centrin, putative 0.0011 0.002 0.032
Schistosoma mansoni hypothetical protein 0.0031 0.0134 0.0134
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.001 0.0012 0.019
Mycobacterium leprae Probable lipase LipE 0.0075 0.0383 1
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.001 0.0012 0.0121
Echinococcus multilocularis replication factor c subunit 1 0.0011 0.0017 0.0021
Mycobacterium ulcerans hypothetical protein 0.0009 0.0006 0.0034
Entamoeba histolytica hypothetical protein, conserved 0.0011 0.002 0.032
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0008 0.0002 0.0062
Mycobacterium leprae PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE [NADP+] DEPENDENT (SSDH) GABD 0.001 0.0012 0.031
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0104 0.0579
Echinococcus multilocularis two pore calcium channel protein 1 0.0021 0.0078 0.0092
Leishmania major programmed cell death 6 protein-like protein 0.0011 0.002 0.0081
Schistosoma mansoni hypothetical protein 0.0011 0.002 0.002
Trypanosoma brucei aldehyde dehydrogenase, putative 0.001 0.0012 0.0033
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0021 0.0078 0.0092
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0078 0.0078
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0078 0.1244
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0017 0.0048
Onchocerca volvulus 0.0043 0.02 0.3209
Mycobacterium leprae Probable exported protease 0.0009 0.0006 0.0161
Plasmodium falciparum epoxide hydrolase 1 0.0009 0.0006 0.0308
Toxoplasma gondii EFHC1, putative 0.0011 0.002 0.0204
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0021 0.0078 0.0078
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.001 0.0012 0.019
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.001 0.0012 0.019
Loa Loa (eye worm) hypothetical protein 0.0021 0.0075 0.012
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0638 0.3615 1
Brugia malayi hypothetical protein 0.0043 0.02 0.02
Onchocerca volvulus 0.0043 0.02 0.3209
Echinococcus multilocularis abhydrolase domain containing 3 0.0009 0.0006 0.0007
Echinococcus multilocularis calcium uptake protein 1 0.0011 0.002 0.0024
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0021 0.0078 0.1244
Echinococcus granulosus potassium voltage gated channel protein 0.0021 0.0078 0.0092
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0067 0.1742
Schistosoma mansoni microtubule-associated protein tau 0.1475 0.8407 0.8407

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 0.004 ug ml-1 Compound was tested in vitro for antibacterial activity against Staphylococcus aureus, pen-res A-9606 ChEMBL. 2918506
MIC (functional) = 0.008 ug ml-1 Compound was tested in vitro for antibacterial activity against Escherichia coli A-15119 ChEMBL. 2918506
MIC (functional) = 0.008 ug ml-1 Compound was tested in vitro for antibacterial activity against Proteus vulgaris A-21559 ChEMBL. 2918506
MIC (functional) = 0.008 ug ml-1 Compound was tested in vitro for antibacterial activity against Escherichia coli A-15119 ChEMBL. 2918506
MIC (functional) = 0.016 ug ml-1 Compound was tested in vitro for antibacterial activity against Serratia marcescens A-20019 ChEMBL. 2918506
MIC (functional) = 0.03 ug ml-1 Compound was tested in vitro for antibacterial activity against Enterobacter cloacae A-9695 ChEMBL. 2918506
MIC (functional) = 2 ug ml-1 Compound was tested in vitro for antibacterial activity against Pseudomonas aeruginosa ChEMBL. 2918506
Relative rate (ADMET) = 0.2 Compound was evaluated for the rate of hydrolysis by renal dipeptidase relative to hog renal dipeptidase ChEMBL. 2918506

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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