Detailed information for compound 275308

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 563.663 | Formula: C31H38FN5O4
  • H donors: 1 H acceptors: 4 LogP: 5.08 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(N[C@@H](C(=O)N1CCN(CC1)CCCOc1ccc(c(c1)F)c1noc(n1)c1ccccc1)C)CC1CCCC1
  • InChi: 1S/C31H38FN5O4/c1-22(33-28(38)20-23-8-5-6-9-23)31(39)37-17-15-36(16-18-37)14-7-19-40-25-12-13-26(27(32)21-25)29-34-30(41-35-29)24-10-3-2-4-11-24/h2-4,10-13,21-23H,5-9,14-20H2,1H3,(H,33,38)/t22-/m1/s1
  • InChiKey: IQWJNZVQZKBYCX-JOCHJYFZSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens histamine receptor H3 Starlite/ChEMBL References
Rattus norvegicus Histamine H3 receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus biogenic amine 5HT receptor Histamine H3 receptor   445 aa 405 aa 25.2 %
Loa Loa (eye worm) hypothetical protein Histamine H3 receptor   445 aa 384 aa 22.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus orexin receptor type 2 0.0079 0.0082 0.0466
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0042 0.0034 0.0193
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0054 0.0049 0.0277
Schistosoma mansoni hypothetical protein 0.0287 0.0353 0.138
Loa Loa (eye worm) hypothetical protein 0.0075 0.0076 0.0291
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0031 0.0072
Onchocerca volvulus 0.0079 0.0082 0.029
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0108 0.012 0.2901
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0041 0.0033 0.0127
Brugia malayi hypothetical protein 0.0037 0.0027 0.0098
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0054 0.0049 0.0184
Loa Loa (eye worm) hypothetical protein 0.011 0.0122 0.0469
Toxoplasma gondii isocitrate dehydrogenase 0.0108 0.012 0.0665
Echinococcus granulosus tm gpcr rhodopsin 0.0079 0.0082 0.0466
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0054 0.0049 0.0184
Echinococcus granulosus sex peptide receptor 0.0079 0.0082 0.0466
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.0082 0.0192
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0075 0.0076 0.0291
Schistosoma mansoni neuropeptide F-like receptor 0.0079 0.0082 0.0322
Echinococcus granulosus enteropeptidase 0.0261 0.0319 0.18
Schistosoma mansoni survival motor neuron protein 0.0045 0.0038 0.0149
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0261 0.0319 0.1245
Echinococcus multilocularis mannose 1 phosphate guanyltransferase beta 0.0037 0.0027 0.0063
Brugia malayi notch-like transmembrane receptor 0.0177 0.021 0.0815
Echinococcus multilocularis high affinity choline transporter 1 0.0383 0.0478 0.1115
Schistosoma mansoni inositol transporter 0.0042 0.0034 0.0133
Mycobacterium ulcerans hypothetical protein 0.1345 0.1732 0.1722
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0175
Onchocerca volvulus 0.0079 0.0082 0.029
Echinococcus granulosus sodium:glucose cotransporter 0.0042 0.0034 0.0193
Loa Loa (eye worm) follicle stimulating hormone receptor 0.021 0.0252 0.0979
Brugia malayi Protein kinase domain containing protein 0.0395 0.0494 0.1925
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0261 0.0319 0.1245
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0054 0.0049 0.0184
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Plasmodium falciparum importin beta, putative 0.0027 0.0014 0.0189
Entamoeba histolytica hypothetical protein 0.003 0.0019 0.1477
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0054 0.0049 0.0184
Schistosoma mansoni nuclear receptor 0.0025 0.0012 0.0047
Schistosoma mansoni amine GPCR 0.0079 0.0082 0.0322
Brugia malayi neuropeptide F receptor 0.0079 0.0082 0.0315
Schistosoma mansoni hypothetical protein 0.0138 0.0159 0.0623
Echinococcus multilocularis mitogen activated protein kinase 0.0029 0.0017 0.0039
Brugia malayi Heterochromatin protein 1 0.0051 0.0046 0.0171
Chlamydia trachomatis UDP-3-O-acylglucosamine N-acyltransferase 0.0037 0.0027 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0039
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0108 0.012 0.2347
Schistosoma mansoni amine GPCR 0.0079 0.0082 0.0322
Brugia malayi Dopamine receptor protein 1 0.0079 0.0082 0.0315
Chlamydia trachomatis acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase 0.0037 0.0027 1
Brugia malayi follicle stimulating hormone receptor 0.021 0.0252 0.0979
Echinococcus multilocularis Niemann Pick C1 protein 0.0092 0.0099 0.023
Schistosoma mansoni hypothetical protein 0.0079 0.0082 0.0322
Echinococcus multilocularis Smad4 0.0018 0.0002 0.0005
Onchocerca volvulus 0.0177 0.021 0.0792
Schistosoma mansoni amine GPCR 0.0079 0.0082 0.0322
Schistosoma mansoni notch 0.0177 0.021 0.0822
Toxoplasma gondii ABC1 family protein 0.0075 0.0076 0.0414
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0032 0.0076
Brugia malayi Calcium binding EGF domain containing protein 0.0177 0.021 0.0815
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0079 0.0082 0.0192
Onchocerca volvulus 0.0261 0.0319 0.1216
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0138 0.0159 0.09
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0027 0.045
Echinococcus granulosus transmembrane protease serine 3 0.0261 0.0319 0.18
Brugia malayi RNA, U transporter 1 0.0076 0.0079 0.03
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0082 0.0322
Trypanosoma cruzi GDP-mannose pyrophosphorylase 0.0038 0.0028 0.0478
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0027 0.0014 0.0048
Echinococcus multilocularis neuropeptides capa receptor 0.0079 0.0082 0.0192
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0098 0.0382
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0017 0.0066
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0079 0.0082 0.0192
Loa Loa (eye worm) hypothetical protein 0.0042 0.0034 0.0126
Echinococcus multilocularis protein jagged 2 0.0177 0.021 0.049
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.0012 0.0028
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0108 0.012 0.0279
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0079 0.0082 0.0322
Onchocerca volvulus 0.0054 0.0049 0.0159
Onchocerca volvulus 0.0079 0.0082 0.029
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.0012 0.0047
Plasmodium vivax hypothetical protein, conserved 0.0075 0.0076 0.1463
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0045 0.0037 0.0138
Trichomonas vaginalis CMGC family protein kinase 0.0029 0.0017 0.0452
Schistosoma mansoni nuclear receptor 0.0025 0.0012 0.0047
Trichomonas vaginalis glucose-1-phosphate thymidylyltransferase, putative 0.0038 0.0028 0.089
Brugia malayi ecdysone receptor 0.0025 0.0012 0.0039
Echinococcus granulosus gamma secretase subunit aph 1 0.0831 0.1062 0.5995
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Echinococcus multilocularis g protein coupled receptor 0.0079 0.0082 0.0192
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.0082 0.0192
Trichomonas vaginalis set domain proteins, putative 0.0221 0.0268 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0012 0.0028
Echinococcus multilocularis neuropeptide receptor A26 0.1375 0.1771 0.4127
Echinococcus granulosus g protein coupled receptor 0.0079 0.0082 0.0466
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0054 0.0049 0.0277
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0029 0.0016 0.0032
Brugia malayi hypothetical protein 0.0079 0.0082 0.0315
Entamoeba histolytica acetyltransferase, putative 0.0037 0.0027 0.2348
Loa Loa (eye worm) hypothetical protein 0.0383 0.0478 0.1862
Echinococcus granulosus chromobox protein 1 0.0051 0.0046 0.0258
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0042 0.0034 0.008
Brugia malayi MAP kinase sur-1 0.0029 0.0017 0.0058
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0079 0.0082 0.0192
Brugia malayi Dopamine receptor protein 2 0.0079 0.0082 0.0315
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.0082 0.0466
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0042 0.0034 0.0169
Brugia malayi Pre-SET motif family protein 0.0028 0.0016 0.0056
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0138 0.0159 0.0371
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0012 0.0068
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0261 0.0319 0.18
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Echinococcus multilocularis fmrfamide receptor 0.0079 0.0082 0.0192
Plasmodium falciparum dynactin subunit 5, putative 0.0037 0.0027 0.045
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0027 0.0838
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.002 0.0005 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0082 0.0322
Schistosoma mansoni laminin gamma-3 chain 0.0177 0.021 0.0822
Echinococcus granulosus allatostatin A receptor 0.0079 0.0082 0.0466
Mycobacterium tuberculosis Probable serine acetyltransferase CysE (sat) 0.0037 0.0027 0.0008
Loa Loa (eye worm) inositol-1 0.0041 0.0032 0.0119
Onchocerca volvulus 0.0079 0.0082 0.029
Onchocerca volvulus 0.0079 0.0082 0.029
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.0067 0.0377
Brugia malayi intermediate filament protein 0.0045 0.0037 0.0138
Loa Loa (eye worm) latrophilin receptor protein 2 0.0138 0.0159 0.0615
Brugia malayi beta-lactamase family protein 0.0075 0.0076 0.0291
Mycobacterium ulcerans transferase 0.0037 0.0027 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.0082 0.0192
Loa Loa (eye worm) isocitrate dehydrogenase 0.0108 0.012 0.0461
Echinococcus multilocularis L aminoadipate semialdehyde 0.0108 0.012 0.028
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0054 0.0049 0.0184
Echinococcus multilocularis smad 0.0018 0.0002 0.0005
Echinococcus multilocularis neurogenic locus notch protein 0.0177 0.021 0.049
Echinococcus granulosus Protein patched homolog 1 0.0039 0.003 0.0172
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0041 0.0033 0.0127
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0465 0.0585 0.2286
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.198 0.2559 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0039
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0261 0.0319 0.1245
Onchocerca volvulus Protein ultraspiracle homolog 0.0054 0.0049 0.0159
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0012 0.0039
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Schistosoma mansoni neuropeptide receptor 0.0079 0.0082 0.0322
Brugia malayi CHE-14 protein 0.0039 0.003 0.0111
Brugia malayi hypothetical protein 0.0261 0.0319 0.1238
Leishmania major hypothetical protein, conserved 0.0037 0.0027 0.045
Schistosoma mansoni amine GPCR 0.0079 0.0082 0.0322
Echinococcus multilocularis isocitrate dehydrogenase 0.0108 0.012 0.0279
Leishmania major hypothetical protein, conserved 0.0097 0.0106 0.2063
Trichomonas vaginalis esterase, putative 0.0075 0.0076 0.2723
Mycobacterium tuberculosis Conserved hypothetical protein 0.1345 0.1732 0.1717
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0079 0.0082 0.0315
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.0012 0.0068
Echinococcus multilocularis fibropellin Ia 0.0177 0.021 0.049
Schistosoma mansoni smad1 5 8 and 0.0018 0.0002 0.0008
Entamoeba histolytica serine acetyltransferase 1 0.0037 0.0027 0.2348
Schistosoma mansoni inositol transporter 0.0042 0.0034 0.0133
Loa Loa (eye worm) hypothetical protein 0.0437 0.0549 0.2138
Plasmodium falciparum ataxin-2 like protein, putative 0.0097 0.0106 0.2063
Brugia malayi hypothetical protein 0.0222 0.0268 0.104
Schistosoma mansoni hypothetical protein 0.0138 0.0159 0.0623
Entamoeba histolytica hypothetical protein 0.004 0.0031 0.2757
Echinococcus granulosus neuropeptide receptor 0.0079 0.0082 0.0466
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.7689 1 1
Brugia malayi Kringle domain containing protein 0.0395 0.0494 0.1925
Schistosoma mansoni mannose-1-phosphate guanyltransferase 0.0038 0.0028 0.011
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Schistosoma mansoni sodium/solute symporter 0.0042 0.0034 0.0133
Echinococcus granulosus Niemann Pick C1 protein 0.0092 0.0099 0.0558
Loa Loa (eye worm) hypothetical protein 0.0465 0.0585 0.228
Brugia malayi Sodium:solute symporter family protein 0.0042 0.0034 0.0126
Echinococcus granulosus geminin 0.115 0.1477 0.8344
Echinococcus granulosus dro:myosuppressin receptor 0.0079 0.0082 0.0466
Brugia malayi tailless protein 0.0025 0.0012 0.0039
Schistosoma mansoni patched 1 0.0039 0.003 0.0119
Schistosoma mansoni inositol monophosphatase 0.0041 0.0032 0.0127
Echinococcus multilocularis beta LACTamase domain containing family member 0.0075 0.0076 0.0178
Echinococcus multilocularis notch 0.0177 0.021 0.049
Echinococcus granulosus L aminoadipate semialdehyde 0.0108 0.012 0.0678
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0108 0.012 0.2347
Brugia malayi hypothetical protein 0.0079 0.0082 0.0315
Brugia malayi hypothetical protein 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0037 0.0027 0.0098
Brugia malayi Bromodomain containing protein 0.0057 0.0053 0.0199
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0027 0.045
Echinococcus multilocularis allatostatin A receptor 0.0079 0.0082 0.0192
Brugia malayi hypothetical protein 0.0037 0.0027 0.0098
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0054 0.0049 0.0114
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0032 0.0563
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0079 0.0082 0.0322
Schistosoma mansoni hypothetical protein 0.0038 0.0029 0.0112
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0079 0.0082 0.0192
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0079 0.0082 0.0322
Trypanosoma cruzi Aph-1 protein, putative 0.0324 0.0401 0.8091
Schistosoma mansoni neuropeptide F-like receptor 0.0079 0.0082 0.0322
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0031 0.002 0.0046
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0075 0.0076 0.0058
Brugia malayi EGF-like domain containing protein 0.0177 0.021 0.0815
Brugia malayi Intermediate filament tail domain containing protein 0.0045 0.0037 0.0138
Schistosoma mansoni Smad4 0.0018 0.0002 0.0008
Brugia malayi Trypsin-like protease protein 5 0.0261 0.0319 0.1238
Echinococcus granulosus neuropeptide Y receptor 0.0079 0.0082 0.0466
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0395 0.0494 1
Trypanosoma brucei PAB1-binding protein , putative 0.0097 0.0106 0.2549
Loa Loa (eye worm) hypothetical protein 0.0075 0.0076 0.0291
Schistosoma mansoni cercarial elastase (S01 family) 0.0261 0.0319 0.1245
Onchocerca volvulus 0.0025 0.0012 0.0014
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0177 0.021 0.0822
Giardia lamblia Kinase, CMGC MAPK 0.0029 0.0017 0.0578
Echinococcus multilocularis Mastin 0.0261 0.0319 0.0743
Echinococcus multilocularis protein jagged 1 0.0177 0.021 0.049
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0079 0.0082 0.0466
Brugia malayi GH02984p 0.0383 0.0478 0.1862
Schistosoma mansoni hypothetical protein 0.0037 0.0027 0.0105
Echinococcus granulosus notch 0.0177 0.021 0.1188
Echinococcus multilocularis musashi 0.0045 0.0037 0.0087
Loa Loa (eye worm) heterochromatin protein 1 0.0051 0.0046 0.0171
Loa Loa (eye worm) hypothetical protein 0.0075 0.0076 0.0291
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0108 0.012 0.2347
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0465 0.0585 0.228
Plasmodium falciparum liver specific protein 2, putative 0.0037 0.0027 0.045
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0079 0.0082 0.0192
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0078
Echinococcus multilocularis expressed conserved protein 0.0086 0.0091 0.0213
Brugia malayi Bromodomain containing protein 0.0028 0.0016 0.0054
Trichomonas vaginalis CMGC family protein kinase 0.0029 0.0017 0.0452
Brugia malayi hypothetical protein 0.004 0.0031 0.0113
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Echinococcus multilocularis glycoprotein Antigen 5 0.0261 0.0319 0.0743
Echinococcus granulosus protein jagged 2 0.0177 0.021 0.1188
Schistosoma mansoni biogenic amine receptor 0.0079 0.0082 0.0322
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0098 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0025
Schistosoma mansoni cercarial elastase (S01 family) 0.0261 0.0319 0.1245
Brugia malayi GDP-mannose pyrophosphorylase B 0.0038 0.0028 0.0103
Brugia malayi Calcitonin receptor-like protein seb-1 0.0437 0.0549 0.2138
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0045 0.0038 0.0089
Brugia malayi RE15519p 0.0079 0.0082 0.0315
Onchocerca volvulus 0.0075 0.0076 0.0267
Loa Loa (eye worm) hypothetical protein 0.0054 0.0049 0.0184
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0054 0.0049 0.0277
Mycobacterium tuberculosis Possible siderophore-binding protein 0.0037 0.0027 0.0008
Echinococcus granulosus neural cadherin 0.0177 0.021 0.1188
Echinococcus granulosus neurogenic locus notch protein 0.0177 0.021 0.1188
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0012 0.0039
Leishmania major hypothetical protein, conserved 0.0037 0.0027 0.045
Entamoeba histolytica hypothetical protein 0.004 0.0031 0.2757
Echinococcus granulosus Smad4 0.0018 0.0002 0.0011
Mycobacterium tuberculosis Probable esterase LipL 0.0075 0.0076 0.0058
Loa Loa (eye worm) hypothetical protein 0.0037 0.0027 0.0098
Brugia malayi Trypsin family protein 0.198 0.2559 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.0067 0.1266
Schistosoma mansoni adenoreceptor 0.0079 0.0082 0.0322
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0098 0.0382
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0082 0.0322
Brugia malayi hypothetical protein 0.0079 0.0082 0.0315
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.0012 0.0068
Loa Loa (eye worm) G-protein coupled receptor 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0016 0.0063
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0076 0.2723
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0029 0.0017 0.0243
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0029 0.0017 0.0069
Toxoplasma gondii eukaryotic initiation factor-2B, epsilon subunit, putative 0.0037 0.0027 0.0128
Loa Loa (eye worm) hypothetical protein 0.0045 0.0037 0.0138
Brugia malayi Delta serrate ligand family protein 0.0177 0.021 0.0815
Echinococcus multilocularis neuropeptide Y receptor 0.0079 0.0082 0.0192
Brugia malayi Cytochrome P450 family protein 0.0048 0.0041 0.0154
Echinococcus granulosus high affinity choline transporter 1 0.0383 0.0478 0.2701
Schistosoma mansoni intermediate filament proteins 0.0045 0.0037 0.0146
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0098 0.0552
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.003 0.0019 0.008
Brugia malayi GCC2 and GCC3 family protein 0.0177 0.021 0.0815
Leishmania major importin beta-1 subunit, putative 0.0022 0.0008 0.0054
Brugia malayi EGF-like domain containing protein 0.0177 0.021 0.0815
Mycobacterium leprae PROBABLE SERINE ACETYLTRANSFERASE CYSE (SAT) 0.0037 0.0027 0.0008
Onchocerca volvulus 0.0079 0.0082 0.029
Echinococcus multilocularis transmembrane protease serine 3 0.0261 0.0319 0.0743
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.0012 0.0047
Mycobacterium leprae POSSIBLE TRANSFERASE 0.0037 0.0027 0.0008
Echinococcus multilocularis sex peptide receptor 0.0079 0.0082 0.0192
Loa Loa (eye worm) hypothetical protein 0.0465 0.0585 0.228
Mycobacterium ulcerans esterase/lipase LipP 0.0075 0.0076 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0016 0.044
Trichomonas vaginalis sugar-1-phosphate guanyl transferase, putative 0.0038 0.0028 0.089
Echinococcus granulosus biogenic amine 5HT receptor 0.0079 0.0082 0.0466
Brugia malayi Cytochrome P450 family protein 0.0025 0.0012 0.0039
Loa Loa (eye worm) MH2 domain-containing protein 0.0258 0.0315 0.1223
Loa Loa (eye worm) nucleotidyl transferase 0.0038 0.0028 0.0103
Echinococcus multilocularis lamin dm0 0.0045 0.0037 0.0087
Echinococcus granulosus g protein coupled receptor 0.0079 0.0082 0.0466
Schistosoma mansoni gdp-mannose pyrophosphorylase b isoform 2 0.0038 0.0028 0.011
Schistosoma mansoni biogenic amine receptor 0.0079 0.0082 0.0322
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.003 0.0019 0.0283
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0054 0.0049 0.0184
Schistosoma mansoni retinoic acid receptor RXR 0.0054 0.0049 0.0191
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0016 0.0055
Loa Loa (eye worm) hypothetical protein 0.0048 0.0042 0.0156
Echinococcus granulosus peptide allatostatin:somatostatin 0.0079 0.0082 0.0466
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0063
Schistosoma mansoni cercarial elastase (S01 family) 0.0261 0.0319 0.1245
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Echinococcus granulosus neuropeptide s receptor 0.1375 0.1771 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0027 0.0106
Echinococcus multilocularis gamma secretase subunit aph 1 0.0831 0.1062 0.2474
Echinococcus multilocularis Tolloid protein 1 0.0465 0.0585 0.1364
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0017 0.0059
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0076 0.0299
Onchocerca volvulus 0.0261 0.0319 0.1216
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0054 0.0049 0.0191
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0054 0.0049 0.0114
Toxoplasma gondii HEAT repeat-containing protein 0.0027 0.0014 0.0054
Echinococcus granulosus mitogen activated protein kinase 3 0.0029 0.0017 0.0095
Brugia malayi EGF-like domain containing protein 0.0177 0.021 0.0815
Mycobacterium tuberculosis Probable lipase LipE 0.0075 0.0076 0.0058
Schistosoma mansoni ran 0.002 0.0005 0.0019
Mycobacterium tuberculosis Conserved protein 0.0075 0.0076 0.0058
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0075 0.0076 0.0065
Echinococcus granulosus lamin dm0 0.0045 0.0037 0.0211
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0079 0.0082 0.0466
Echinococcus multilocularis FTZ F1 alpha 0.0054 0.0049 0.0114
Echinococcus granulosus survival motor neuron protein 1 0.0222 0.0268 0.1513
Loa Loa (eye worm) hypothetical protein 0.0075 0.0076 0.0291
Schistosoma mansoni coup transcription factor 0.0054 0.0049 0.0191
Mycobacterium ulcerans beta-lactamase 0.0075 0.0076 0.0065
Brugia malayi MH2 domain containing protein 0.0258 0.0315 0.1223
Loa Loa (eye worm) hypothetical protein 0.0465 0.0585 0.228
Loa Loa (eye worm) hypothetical protein 0.106 0.136 0.531
Brugia malayi eIF4-gamma/eIF5/eIF2-epsilon family protein 0.0037 0.0027 0.0098
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0079 0.0082 0.0466
Onchocerca volvulus 0.198 0.2559 1
Brugia malayi Calcium binding EGF domain containing protein 0.0177 0.021 0.0815
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0054 0.0049 0.0184
Loa Loa (eye worm) neuropeptide F receptor 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0261 0.0319 0.1238
Echinococcus granulosus tm gpcr rhodopsin 0.0805 0.1028 0.5807
Brugia malayi neuropeptide F receptor 0.0079 0.0082 0.0315
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.003 0.0019 0.0283
Onchocerca volvulus 0.0029 0.0017 0.0034
Loa Loa (eye worm) GDP-mannose pyrophosphorylase B 0.0038 0.0028 0.0103
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0079 0.0082 0.029
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0079 0.0082 0.0466
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0025
Brugia malayi latrophilin 2 splice variant baaae 0.0299 0.0369 0.1433
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0027 0.0556
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0018 0.0003 0.0007
Brugia malayi hypothetical protein 0.0037 0.0027 0.0098
Schistosoma mansoni hypothetical protein 0.0045 0.0038 0.0149
Loa Loa (eye worm) hypothetical protein 0.0054 0.0049 0.0184
Loa Loa (eye worm) hypothetical protein 0.0092 0.0099 0.0378
Mycobacterium ulcerans hypothetical protein 0.0075 0.0076 0.0065
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.0082 0.0192
Brugia malayi Nucleotidyl transferase family protein 0.0038 0.0028 0.0103
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Brugia malayi Trypsin family protein 0.0261 0.0319 0.1238
Loa Loa (eye worm) transcription factor SMAD2 0.0258 0.0315 0.1223
Leishmania major serine acetyltransferase 0.0037 0.0027 0.045
Schistosoma mansoni notch 0.0177 0.021 0.0822
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0016 0.0063
Leishmania major phosphopantetheinyl transferase-like protein 0.003 0.0019 0.0283
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0032 0.1049
Loa Loa (eye worm) hypothetical protein 0.0054 0.0049 0.0184
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0082 0.0322
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0075 0.0076 0.0058
Wolbachia endosymbiont of Brugia malayi 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 0.0037 0.0027 0.0008
Mycobacterium tuberculosis Probable lipase LipD 0.0075 0.0076 0.0058
Toxoplasma gondii eukaryotic initiation factor 2B epsilon subunit, putative 0.0037 0.0027 0.0128
Onchocerca volvulus 0.0177 0.021 0.0792
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0012 0.0047
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0045 0.0038 0.0217
Brugia malayi Inositol-1 0.0041 0.0032 0.0119
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0108 0.012 0.2347
Echinococcus granulosus slit 2 protein 0.0177 0.021 0.1188
Onchocerca volvulus 0.0079 0.0082 0.029
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Schistosoma mansoni hypothetical protein 0.0177 0.021 0.0822
Loa Loa (eye worm) hypothetical protein 0.0028 0.0016 0.0055
Echinococcus multilocularis GPCR, family 2 0.0138 0.0159 0.0371
Schistosoma mansoni glucosamine-1-phosphate N-acetyltransferase 0.0038 0.0028 0.011
Schistosoma mansoni biogenic amine (5HT) receptor 0.0079 0.0082 0.0322
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0054 0.0049 0.0277
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0093 0.0101 0.0393
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0067 0.0261
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0054 0.0049 0.0184
Trypanosoma brucei cytochrome P450, putative 0.0025 0.0012 0.0176
Echinococcus multilocularis G protein coupled receptor 139 0.0079 0.0082 0.0192
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0054 0.0049 0.0191
Echinococcus granulosus mitogen activated protein kinase 0.0029 0.0017 0.0095
Entamoeba histolytica acetyltransferase, putative 0.0037 0.0027 0.2348
Mycobacterium ulcerans lipase LipD 0.0075 0.0076 0.0065
Schistosoma mansoni notch 0.0177 0.021 0.0822
Brugia malayi chromobox protein homolog 3 0.0029 0.0016 0.0057
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0054 0.0049 0.0277
Mycobacterium ulcerans hypothetical protein 0.0261 0.0319 0.0307
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Entamoeba histolytica maltose O-acetyltransferase, putative 0.0037 0.0027 0.2348
Brugia malayi GnHR receptor homolog 0.0079 0.0082 0.0315
Echinococcus granulosus neurogenic locus protein delta 0.0177 0.021 0.1188
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.0012 0.0039
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.0012 0.0039
Echinococcus multilocularis g protein coupled receptor 0.0079 0.0082 0.0192
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0027 0.045
Brugia malayi gamma-secretase subunit aph-1 0.0831 0.1062 0.4143
Loa Loa (eye worm) hypothetical protein 0.198 0.2559 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0079 0.0082 0.0322
Loa Loa (eye worm) CYP4Cod1 0.0025 0.0012 0.0039
Brugia malayi Cadherin domain containing protein 0.0177 0.021 0.0815
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0012 0.0142
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0054 0.0049 0.0114
Loa Loa (eye worm) hypothetical protein 0.0465 0.0585 0.228
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0805 0.1028 0.2396
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.0027 0.0008
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Onchocerca volvulus 0.1719 0.222 0.8669
Brugia malayi Tachykinin-like peptides receptor 99D 0.0079 0.0082 0.0315
Mycobacterium leprae Probable lipase LipE 0.0075 0.0076 0.0058
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0079 0.0082 0.0322
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0041 0.0033 0.0119
Brugia malayi nuclear receptor NHR-67 0.0025 0.0012 0.0039
Toxoplasma gondii GDP-D-mannose pyrophosphorylase 0.0038 0.0028 0.0135
Brugia malayi PHD-finger family protein 0.002 0.0005 0.0012
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0032 0.0563
Echinococcus granulosus cpg binding protein 0.0032 0.0021 0.0119
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0054 0.0049 0.0184
Schistosoma mansoni slit 0.0177 0.021 0.0822
Echinococcus multilocularis neurogenic locus protein delta 0.0177 0.021 0.049
Brugia malayi nuclear receptor NHR-88 0.0054 0.0049 0.0184
Echinococcus multilocularis protein patched 0.0039 0.003 0.0071
Echinococcus granulosus histone lysine methyltransferase setb 0.0041 0.0033 0.0184
Echinococcus granulosus protein jagged 1 0.0177 0.021 0.1188
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0054 0.0049 0.0184
Schistosoma mansoni neuropeptide receptor 0.0079 0.0082 0.0322
Onchocerca volvulus 0.0079 0.0082 0.029
Echinococcus granulosus serotonin receptor 0.0079 0.0082 0.0466
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0028 0.0016 0.0063
Leishmania major GDP-mannose pyrophosphorylase 0.0038 0.0028 0.0478
Onchocerca volvulus Putative cubilin 0.0177 0.021 0.0792
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Echinococcus granulosus fmrfamide receptor 0.0079 0.0082 0.0466
Loa Loa (eye worm) hypothetical protein 0.0028 0.0016 0.0054
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.0067 0.0156
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0054 0.0049 0.0191
Schistosoma mansoni hypothetical protein 0.0177 0.021 0.0822
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0079 0.0082 0.0315
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3308 0.429 1
Loa Loa (eye worm) GDP-mannose pyrophosphorylase B 0.0037 0.0027 0.0098
Brugia malayi hypothetical protein 0.0079 0.0082 0.0315
Echinococcus multilocularis neuropeptides capa receptor 0.0079 0.0082 0.0192
Loa Loa (eye worm) hypothetical protein 0.0261 0.0319 0.1238
Brugia malayi hypothetical protein 0.0079 0.0082 0.0315
Trypanosoma cruzi serine acetyltransferase, putative 0.0037 0.0027 0.045
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0019 0.035
Echinococcus multilocularis enteropeptidase 0.0261 0.0319 0.0743
Onchocerca volvulus 0.0075 0.0076 0.0267
Brugia malayi CXXC zinc finger family protein 0.0029 0.0017 0.0059
Onchocerca volvulus 0.0045 0.0037 0.0113
Schistosoma mansoni neuropeptide receptor 0.0079 0.0082 0.0322
Brugia malayi Trypsin family protein 0.0261 0.0319 0.1238
Onchocerca volvulus 0.106 0.136 0.5299
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0054 0.0049 0.0114
Leishmania major hypothetical protein, conserved 0.0395 0.0494 1
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0012 0.0047
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.002 0.0005 0.0011
Echinococcus multilocularis importin subunit beta 1 0.0027 0.0014 0.0033
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0041 0.0033 0.0076
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0076 0.2723
Brugia malayi Serotonin receptor 0.0079 0.0082 0.0315
Trypanosoma cruzi Aph-1 protein, putative 0.0324 0.0401 0.8091
Brugia malayi nuclear hormone receptor 0.0054 0.0049 0.0184
Echinococcus multilocularis neuropeptide Y receptor 0.0079 0.0082 0.0192
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0046 0.1554
Echinococcus granulosus tissue type plasminogen activator 0.0395 0.0494 0.2792
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0028 0.0016 0.0037
Echinococcus multilocularis g-protein coupled receptor 0.0079 0.0082 0.0192
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0098 0.0374
Echinococcus multilocularis fmrfamide receptor 0.0079 0.0082 0.0192
Echinococcus granulosus tachykinin peptides receptor 99D 0.0079 0.0082 0.0466
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0039
Onchocerca volvulus 0.0261 0.0319 0.1216
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0082 0.0322
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0076 0.2723
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0177 0.021 0.0815
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0002 0.0008
Mycobacterium tuberculosis Conserved hypothetical protein 0.0037 0.0027 0.0008
Loa Loa (eye worm) dynactin 5 0.0037 0.0027 0.0098
Echinococcus granulosus importin subunit beta 1 0.0027 0.0014 0.008
Echinococcus multilocularis snurportin 1 0.0287 0.0353 0.0823
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0029 0.0017 0.0243
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0076 0.1463
Onchocerca volvulus 0.0025 0.0012 0.0014
Schistosoma mansoni biogenic amine (5HT) receptor 0.0079 0.0082 0.0322
Echinococcus multilocularis G-protein coupled receptor, putative 0.0079 0.0082 0.0192
Onchocerca volvulus 0.0042 0.0034 0.0101
Schistosoma mansoni notch 0.0177 0.021 0.0822
Echinococcus multilocularis GTP binding nuclear protein Ran 0.002 0.0005 0.0011
Schistosoma mansoni hypothetical protein 0.0079 0.0082 0.0322
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0016 0.0055
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0002 0.0005
Loa Loa (eye worm) trypsin family protein 0.0261 0.0319 0.1238
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0465 0.0585 0.228
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0082 0.0322
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.0041 0.0154
Brugia malayi EGF-like domain containing protein 0.0177 0.021 0.0815
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0032 0.2939
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0022 0.0008 0.01
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Onchocerca volvulus 0.0037 0.0027 0.0073
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0022 0.0007 0.0017
Echinococcus granulosus snurportin 1 0.0287 0.0353 0.1994
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0054 0.0049 0.0184
Onchocerca volvulus 0.0079 0.0082 0.029
Leishmania major cytochrome p450-like protein 0.0025 0.0012 0.0142
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Echinococcus granulosus sodium:myo inositol cotransporter 0.0042 0.0034 0.0193
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0028 0.0016 0.0055
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.0012 0.0047
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.0027 0.0008
Schistosoma mansoni cpg binding protein 0.0029 0.0017 0.0067
Echinococcus multilocularis dro:myosuppressin receptor 0.0079 0.0082 0.0192
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0054 0.0049 0.0159
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0032 0.0696
Trypanosoma cruzi Translation initiation factor eIF-2B subunit epsilon, putative 0.0038 0.0028 0.0478
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0082 0.0322
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0016 0.044
Loa Loa (eye worm) hypothetical protein 0.0108 0.012 0.0462
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0026 0.0013 0.0076
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0465 0.0585 0.228
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0465 0.0585 0.228
Brugia malayi G-protein coupled receptor 0.0079 0.0082 0.0315
Brugia malayi isocitrate dehydrogenase 0.0108 0.012 0.0461
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0079 0.0082 0.0192
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0031 0.002 0.0112
Schistosoma mansoni hypothetical protein 0.0177 0.021 0.0822
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0437 0.0549 0.2138
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0026 0.0013 0.0031
Echinococcus granulosus GTP binding nuclear protein Ran 0.002 0.0005 0.0028
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0076 0.0299
Schistosoma mansoni hypothetical protein 0.0177 0.021 0.0822
Brugia malayi Melatonin receptor type 1A 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Onchocerca volvulus Arrow homolog 0.0465 0.0585 0.2261
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0054 0.0049 0.0191
Toxoplasma gondii EGF family domain-containing protein 0.0177 0.021 0.1189
Trypanosoma brucei protein kinase, putative 0.0029 0.0017 0.03
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0039
Echinococcus granulosus chromobox protein 1 0.0051 0.0046 0.0258
Echinococcus granulosus ecdysone induced protein 78C 0.0054 0.0049 0.0277
Onchocerca volvulus 0.0261 0.0319 0.1216
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.1345 0.1732 1
Echinococcus granulosus neurogenic locus notch protein 0.0177 0.021 0.1188
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0261 0.0319 0.1238
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0054 0.0049 0.0114
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.7689 1 1
Loa Loa (eye worm) hypothetical protein 0.0097 0.0106 0.0406
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Entamoeba histolytica maltose O-acetyltransferase, putative 0.0037 0.0027 0.2348
Onchocerca volvulus Bile acid receptor homolog 0.0054 0.0049 0.0159
Echinococcus multilocularis ecdysone induced protein 78C 0.0054 0.0049 0.0114
Onchocerca volvulus 0.0079 0.0082 0.029
Loa Loa (eye worm) hypothetical protein 0.0261 0.0319 0.1238
Echinococcus multilocularis somatostatin receptor 0.0079 0.0082 0.0192
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0079 0.0082 0.0192
Schistosoma mansoni egf-like domain protein 0.0465 0.0585 0.2286
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.0082 0.0466
Brugia malayi photoreceptor-specific nuclear receptor 0.0054 0.0049 0.0184
Echinococcus granulosus laminin 0.0465 0.0585 0.3305
Echinococcus multilocularis neural cadherin 0.0177 0.021 0.049
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0061 0.0239
Schistosoma mansoni opsin-like receptor 0.0079 0.0082 0.0322
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0012 0.0028
Brugia malayi G-protein coupled receptor 0.0079 0.0082 0.0315
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0002 0.0011
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0031 0.0174
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0039
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0079 0.0082 0.0192
Echinococcus multilocularis mitogen activated protein kinase 3 0.0029 0.0017 0.0039
Schistosoma mansoni hypothetical protein 0.0261 0.0319 0.1245
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0079 0.0082 0.0315
Onchocerca volvulus 0.0221 0.0268 0.1017
Brugia malayi hypothetical protein 0.0025 0.0012 0.0039
Onchocerca volvulus 0.0079 0.0082 0.029
Trypanosoma cruzi GDP-mannose pyrophosphorylase 0.0038 0.0028 0.0478
Schistosoma mansoni hypothetical protein 0.0177 0.021 0.0822
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Echinococcus multilocularis neuropeptide s receptor 0.1375 0.1771 0.4127
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.003 0.0972
Echinococcus multilocularis chromobox protein 1 0.0051 0.0046 0.0107
Echinococcus granulosus mannose 1 phosphate guanyltransferase beta 0.0038 0.0028 0.016
Leishmania major hypothetical protein, conserved 0.0075 0.0076 0.1463
Echinococcus granulosus fibropellin Ia 0.0177 0.021 0.1188
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0098 0.0228
Onchocerca volvulus 0.0045 0.0038 0.0116
Brugia malayi Pre-SET motif family protein 0.0195 0.0233 0.0903
Loa Loa (eye worm) hypothetical protein 0.0465 0.0585 0.228
Schistosoma mansoni hypothetical protein 0.0038 0.0029 0.0112
Onchocerca volvulus 0.0079 0.0082 0.029
Schistosoma mansoni lamin 0.0045 0.0037 0.0146
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0039
Echinococcus granulosus FTZ F1 alpha 0.0054 0.0049 0.0277
Schistosoma mansoni DNA polymerase epsilon catalytic subunit 0.0037 0.0027 0.0105
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0028 0.0016 0.0091
Trypanosoma brucei GDP-mannose pyrophosphorylase 0.0038 0.0028 0.059
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0079 0.0082 0.0322
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0042 0.0034 0.008
Schistosoma mansoni nuclear hormone receptor 0.0054 0.0049 0.0191
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Echinococcus multilocularis g protein coupled receptor 0.0079 0.0082 0.0192
Echinococcus granulosus 7tm_1 domain containing protein 0.0079 0.0082 0.0466
Onchocerca volvulus 0.0177 0.021 0.0792
Brugia malayi Importin beta-1 subunit 0.0027 0.0014 0.0048
Echinococcus granulosus G protein coupled receptor 139 0.0079 0.0082 0.0466
Loa Loa (eye worm) TK/ROR protein kinase 0.0395 0.0494 0.1925
Mycobacterium ulcerans serine acetyltransferase CysE 0.0037 0.0027 0.0015
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Echinococcus granulosus fetal alzheimer antigen falz 0.0018 0.0003 0.0016
Echinococcus granulosus mannose 1 phosphate guanyltransferase beta 0.0037 0.0027 0.0152
Onchocerca volvulus 0.0177 0.021 0.0792
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.0082 0.0466
Schistosoma mansoni hypothetical protein 0.0079 0.0082 0.0322
Schistosoma mansoni cpg binding protein 0.0032 0.0021 0.0083
Schistosoma mansoni cpg binding protein 0.0032 0.0021 0.0083
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0042 0.0034 0.008
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0054 0.0049 0.0184
Schistosoma mansoni cercarial elastase (S01 family) 0.0261 0.0319 0.1245
Schistosoma mansoni notch 0.0177 0.021 0.0822
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0261 0.0319 0.18
Mycobacterium ulcerans d-alpha-D-mannose-1-phosphate guanylyltransferase ManB 0.0038 0.0028 0.0016
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.0012 0.0039
Echinococcus multilocularis protein jagged 1 0.0177 0.021 0.049
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0079 0.0082 0.0192
Entamoeba histolytica hypothetical protein 0.004 0.0031 0.2757
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0044 0.0036 0.0084
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0079 0.0082 0.0192
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0054 0.0049 0.0184
Echinococcus granulosus expressed conserved protein 0.0086 0.0091 0.0517
Loa Loa (eye worm) hypothetical protein 0.0075 0.0076 0.0291
Echinococcus granulosus sterol regulatory element binding protein 0.0039 0.003 0.0172
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Brugia malayi zgc:92842 0.0037 0.0027 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0025
Echinococcus granulosus Mastin 0.0261 0.0319 0.18
Brugia malayi AKH receptor 0.0079 0.0082 0.0315
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0027 0.0556
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0098 0.0552
Brugia malayi hypothetical protein 0.0028 0.0016 0.0055
Entamoeba histolytica translation initiation factor eIF-2B epsilon subunit, putative 0.0038 0.0028 0.2492
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0067 0.0261
Loa Loa (eye worm) hypothetical protein 0.0054 0.0049 0.0184
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0076 0.1463
Loa Loa (eye worm) hypothetical protein 0.0138 0.0159 0.0615
Loa Loa (eye worm) hypothetical protein 0.0299 0.0369 0.1433
Schistosoma mansoni septate junction protein 0.0177 0.021 0.0822
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0054 0.0049 0.0184
Mycobacterium leprae conserved hypothetical protein 0.0075 0.0076 0.0058
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0076 0.2723
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0079 0.0082 0.0192
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0067 0.0055
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0031 0.012
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0054 0.0049 0.0184
Echinococcus granulosus sodium:glucose cotransporter 2 0.0042 0.0034 0.0193
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.0067 0.0359
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0054 0.0049 0.0184
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0079 0.0082 0.0322
Schistosoma mansoni hypothetical protein 0.0138 0.0159 0.0623
Echinococcus multilocularis lamin 0.0045 0.0037 0.0087
Schistosoma mansoni thyroid hormone receptor 0.0054 0.0049 0.0191
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Plasmodium vivax ataxin-2 like protein, putative 0.0097 0.0106 0.2063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0054 0.0049 0.0184
Loa Loa (eye worm) DR-78 0.0025 0.0012 0.0039
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0012 0.0028
Plasmodium vivax dynactin subunit 5, putative 0.0037 0.0027 0.045
Echinococcus multilocularis fibrillin 1 0.0465 0.0585 0.1364
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0108 0.012 0.0676
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0037 0.0027 0.0015
Schistosoma mansoni RAR-like nuclear receptor 0.0054 0.0049 0.0191
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0108 0.012 0.0469
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0054 0.0049 0.0191
Echinococcus multilocularis laminin 0.0465 0.0585 0.1364
Plasmodium vivax mannose-1-phosphate guanyltransferase, putative 0.0038 0.0028 0.0478
Brugia malayi sulfakinin receptor protein 0.0079 0.0082 0.0315
Onchocerca volvulus 0.0079 0.0082 0.029
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0019 0.0548
Onchocerca volvulus 0.0108 0.012 0.0438
Echinococcus granulosus beta LACTamase domain containing family member 0.0075 0.0076 0.0432
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0098 0.0382
Onchocerca volvulus 0.0079 0.0082 0.029
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0016
Brugia malayi Calcium binding EGF domain containing protein 0.0465 0.0585 0.228
Brugia malayi Muscleblind-like protein 0.011 0.0122 0.0469
Echinococcus granulosus mannose 1 phosphate guanyltransferase 0.0038 0.0028 0.016
Echinococcus multilocularis orexin receptor type 2 0.0079 0.0082 0.0192
Echinococcus multilocularis geminin 0.115 0.1477 0.3444
Loa Loa (eye worm) hypothetical protein 0.0028 0.0016 0.0055
Entamoeba histolytica ankyrin, putative 0.0037 0.0027 0.2348
Echinococcus multilocularis muscleblind protein 1 0.011 0.0122 0.0284
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0054 0.0049 0.0191
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0027 0.0556
Wolbachia endosymbiont of Brugia malayi carbonic anhydrase 0.0037 0.0027 0.0008
Schistosoma mansoni inositol monophosphatase 0.0041 0.0032 0.0127
Echinococcus multilocularis slit 2 protein 0.0177 0.021 0.049
Schistosoma mansoni hypothetical protein 0.115 0.1477 0.5773
Toxoplasma gondii calcium binding egf domain-containing protein 0.0465 0.0585 0.336
Brugia malayi G protein-coupled receptor F59B2.13 0.0079 0.0082 0.0315
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0029 0.0017 0.0243
Brugia malayi beta-lactamase family protein 0.0075 0.0076 0.0291
Schistosoma mansoni hypothetical protein 0.0177 0.021 0.0822
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.0012 0.0028
Brugia malayi hypothetical protein 0.0063 0.0061 0.023
Trypanosoma cruzi PAB1-binding protein , putative 0.0097 0.0106 0.2063
Schistosoma mansoni smad1 5 8 and 0.0018 0.0002 0.0008
Entamoeba histolytica bacterial transferase hexapeptide family protein 0.0037 0.0027 0.2348
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0195 0.0233 0.0903
Trypanosoma brucei Aph-1 protein, putative 0.0324 0.0401 1
Brugia malayi Steroid receptor seven-up type 2 0.0054 0.0049 0.0184
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0079 0.0082 0.0315
Echinococcus multilocularis neurogenic locus notch protein 0.0177 0.021 0.049
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Plasmodium falciparum ataxin-2 like protein, putative 0.0097 0.0106 0.2063
Echinococcus multilocularis neurogenic locus protein delta 0.0177 0.021 0.049
Trypanosoma cruzi PAB1-binding protein , putative 0.0097 0.0106 0.2063
Mycobacterium tuberculosis Conserved protein 0.0075 0.0076 0.0058
Trypanosoma cruzi importin beta-1 subunit, putative 0.0022 0.0008 0.0054
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0032 0.0183
Schistosoma mansoni zinc finger protein 0.0025 0.0012 0.0047
Trypanosoma brucei nucleotidyl transferase, putative 0.0038 0.0028 0.059
Loa Loa (eye worm) hypothetical protein 0.0039 0.003 0.0111
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0028 0.0016 0.0038
Echinococcus granulosus neuropeptide FF receptor 2 0.0079 0.0082 0.0466
Entamoeba histolytica acetyltransferase, putative 0.0037 0.0027 0.2348
Echinococcus multilocularis survival motor neuron protein 1 0.0222 0.0268 0.0624
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Brugia malayi nuclear hormone receptor 0.0025 0.0012 0.0039
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0022 0.0007 0.0041
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0039
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0092 0.0099 1
Brugia malayi Cadherin domain containing protein 0.0177 0.021 0.0815
Trichomonas vaginalis CMGC family protein kinase 0.0029 0.0017 0.0452
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0027 0.045
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0012 0.0014
Schistosoma mansoni smad 0.0018 0.0002 0.0008
Echinococcus granulosus intermediate filament protein 0.0045 0.0037 0.0211
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0032 0.0021
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.1345 0.1732 0.1722
Schistosoma mansoni dynactin subunit P25 0.0037 0.0027 0.0105
Trypanosoma cruzi hypothetical protein 0.0037 0.0027 0.045
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0055 0.0289
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.0082 0.0192
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0029 0.0017 0.0243
Trypanosoma brucei hypothetical protein, conserved 0.0075 0.0076 0.1808
Entamoeba histolytica acetyltransferase, putative 0.0037 0.0027 0.2348
Brugia malayi ecdysteroid receptor 0.0054 0.0049 0.0184
Trichomonas vaginalis maltose O-acetyltransferase, putative 0.0037 0.0027 0.0838
Schistosoma mansoni thyroid hormone receptor 0.0054 0.0049 0.0191
Brugia malayi Cytochrome P450 family protein 0.0025 0.0012 0.0039
Schistosoma mansoni hypothetical protein 0.004 0.0031 0.012
Echinococcus granulosus protein jagged 2 0.0177 0.021 0.1188
Mycobacterium tuberculosis Conserved hypothetical protein 0.1345 0.1732 0.1717
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Schistosoma mansoni hypothetical protein 0.115 0.1477 0.5773
Loa Loa (eye worm) TYRA-2 protein 0.0079 0.0082 0.0315
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.0082 0.0466
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0082 0.0322
Schistosoma mansoni ran 0.002 0.0005 0.0019
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0079 0.0082 0.0315
Brugia malayi EGF-like domain containing protein 0.0177 0.021 0.0815
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0022 0.0008 0.01
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Toxoplasma gondii kringle domain-containing protein 0.0395 0.0494 0.2834
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0477 0.0601 0.0584
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0261 0.0319 0.1245
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0057
Echinococcus multilocularis neuropeptide FF receptor 2 0.0079 0.0082 0.0192
Schistosoma mansoni importin beta-1 0.0027 0.0014 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0054 0.0049 0.0184
Echinococcus multilocularis chromobox protein 1 0.0051 0.0046 0.0107
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0054 0.0049 0.0277
Brugia malayi hypothetical protein 0.0079 0.0082 0.0315
Echinococcus granulosus neuropeptides capa receptor 0.0079 0.0082 0.0466
Schistosoma mansoni opsin-like receptor 0.0079 0.0082 0.0322
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0287 0.0353 0.1373
Echinococcus granulosus g protein coupled receptor 0.0079 0.0082 0.0466
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0079 0.0082 0.0315
Brugia malayi nuclear receptor RXR 0.0025 0.0012 0.0039
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.0082 0.0192
Toxoplasma gondii isocitrate dehydrogenase 0.0108 0.012 0.0665
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0079 0.0082 0.0466
Echinococcus granulosus solute carrier family 5 0.0042 0.0034 0.0193
Echinococcus granulosus delta-like protein 1 0.0177 0.021 0.1188
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0079 0.0082 0.0315
Echinococcus granulosus 7TM GPCR rhodopsin 0.0079 0.0082 0.0466
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0261 0.0319 0.0743
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0079 0.0082 0.0322
Entamoeba histolytica bacterial transferase hexapeptide family protein 0.0037 0.0027 0.2348
Loa Loa (eye worm) hypothetical protein 0.0261 0.0319 0.1238
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0031 0.0019 0.0043
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0067 0.0055
Trichomonas vaginalis maltose O-acetyltransferase, putative 0.0037 0.0027 0.0838
Brugia malayi cytoplasmic intermediate filament protein 0.0024 0.001 0.0032
Toxoplasma gondii calcium binding egf domain-containing protein 0.0465 0.0585 0.336
Schistosoma mansoni hypothetical protein 0.0038 0.0029 0.0112
Echinococcus multilocularis serotonin receptor 0.0079 0.0082 0.0192
Brugia malayi Fibulin-1 precursor 0.0465 0.0585 0.228
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0027 0.0014 0.0079
Schistosoma mansoni bromodomain containing protein 0.0048 0.0042 0.0163
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0079 0.0082 0.0322
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0079 0.0082 0.0322
Trypanosoma cruzi serine acetyltransferase, putative 0.0037 0.0027 0.045
Schistosoma mansoni cell polarity protein 0.0177 0.021 0.0822
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0108 0.012 0.0279
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0029 0.0017 0.0243
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0019 0.0548
Leishmania major hypothetical protein, conserved 0.0037 0.0027 0.045
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0079 0.0082 0.0315
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.0082 0.0192
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0067 0.0055
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.003 0.0019 0.0007
Brugia malayi steroid hormone receptor 0.0054 0.0049 0.0184
Loa Loa (eye worm) nuclear hormone receptor 0.0025 0.0012 0.0039
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0079 0.0082 0.0322
Brugia malayi EGF-like domain containing protein 0.0177 0.021 0.0815
Loa Loa (eye worm) hypothetical protein 0.0028 0.0016 0.0055
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0039
Brugia malayi nuclear receptor RXR 0.0028 0.0016 0.0055
Schistosoma mansoni opsin-like receptor 0.0079 0.0082 0.0322
Trypanosoma cruzi hypothetical protein, conserved 0.0395 0.0494 1
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.0012 0.0039
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0138 0.0159 0.09
Onchocerca volvulus 0.0177 0.021 0.0792
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0831 0.1062 0.4143
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0054 0.0049 0.0184
Mycobacterium ulcerans hypothetical protein 0.0037 0.0027 0.0015
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Giardia lamblia Translation initiation factor 0.0037 0.0027 0.1073
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.0012 0.0039
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0024 0.001 0.0032
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Loa Loa (eye worm) hypothetical protein 0.011 0.0122 0.0469
Plasmodium falciparum cysteine repeat modular protein 1 0.0395 0.0494 1
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.0012 0.0039
Echinococcus granulosus neurogenic locus notch protein 4 0.0177 0.021 0.1188
Loa Loa (eye worm) hypothetical protein 0.0054 0.0049 0.0184
Loa Loa (eye worm) hypothetical protein 0.198 0.2559 1
Plasmodium falciparum mannose-1-phosphate guanyltransferase, putative 0.0038 0.0028 0.0478
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Onchocerca volvulus Neuropeptide F receptor homolog 0.0079 0.0082 0.029
Loa Loa (eye worm) Notch2 0.0177 0.021 0.0815
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0029 0.0017 0.0243
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0079 0.0082 0.0322
Onchocerca volvulus 0.0079 0.0082 0.029
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Echinococcus multilocularis protein dispatched 1 0.0045 0.0038 0.0088
Echinococcus granulosus hypothetical protein 0.0079 0.0082 0.0466
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0039
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0032 0.1049
Echinococcus multilocularis mannose 1 phosphate guanyltransferase beta 0.0038 0.0028 0.0066
Schistosoma mansoni cercarial elastase (S01 family) 0.0261 0.0319 0.1245
Brugia malayi Isocitrate dehydrogenase 0.0108 0.012 0.0461
Schistosoma mansoni chromobox protein 0.0051 0.0046 0.0179
Loa Loa (eye worm) hypothetical protein 0.0054 0.0049 0.0184
Echinococcus multilocularis muscleblind protein 0.011 0.0122 0.0284
Schistosoma mansoni biogenic amine receptor 0.0079 0.0082 0.0322
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0012 0.0142
Onchocerca volvulus 0.0045 0.0037 0.0113
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.0082 0.0466
Loa Loa (eye worm) hypothetical protein 0.0261 0.0319 0.1238
Toxoplasma gondii LsmAD domain-containing protein 0.0097 0.0106 0.0584
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.003 0.0019 0.0007
Entamoeba histolytica acetyltransferase, putative 0.0037 0.0027 0.2348
Entamoeba histolytica serine acetyltransferase, putative 0.0037 0.0027 0.2348
Schistosoma mansoni histamine h1 receptor 0.0079 0.0082 0.0322
Schistosoma mansoni myosin xvIII 0.0079 0.0082 0.0322
Schistosoma mansoni cercarial elastase (S01 family) 0.0261 0.0319 0.1245
Brugia malayi hypothetical protein 0.0028 0.0016 0.0055
Echinococcus granulosus biogenic amine 5HT receptor 0.0079 0.0082 0.0466
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0079 0.0082 0.0322
Brugia malayi Dopamine receptor 0.0079 0.0082 0.0315
Entamoeba histolytica acetyltransferase, putative 0.0037 0.0027 0.2348
Trypanosoma brucei importin beta-1 subunit, putative 0.0027 0.0014 0.0234
Brugia malayi beta-lactamase 0.0075 0.0076 0.0291
Echinococcus granulosus tm gpcr rhodopsin 0.0079 0.0082 0.0466
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0032 0.0014
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0054 0.0049 0.0277
Onchocerca volvulus 0.0261 0.0319 0.1216
Schistosoma mansoni hypothetical protein 0.0177 0.021 0.0822
Trichomonas vaginalis mannose-1-phosphate guanyltransferase, putative 0.0037 0.0027 0.0838
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0079 0.0082 0.0192
Echinococcus multilocularis tissue type plasminogen activator 0.0395 0.0494 0.1152
Echinococcus multilocularis sterol regulatory element binding protein 0.0039 0.003 0.0071
Brugia malayi hypothetical protein 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0075 0.0076 0.0291
Brugia malayi hypothetical protein 0.0025 0.0012 0.0039
Echinococcus granulosus alpha 1A adrenergic receptor 0.0079 0.0082 0.0466
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0054 0.0049 0.0184
Echinococcus multilocularis fat cadherin tumor suppressor 0.0177 0.021 0.049
Entamoeba histolytica serine acetyltransferase 1 0.0037 0.0027 0.2348
Echinococcus granulosus Niemann Pick C1 protein 0.0131 0.015 0.0848
Echinococcus granulosus neuropeptide Y receptor 0.0079 0.0082 0.0466
Schistosoma mansoni high-affinity choline transporter 0.0383 0.0478 0.1868
Echinococcus multilocularis neuropeptide receptor 0.0079 0.0082 0.0192
Loa Loa (eye worm) intermediate filament protein 0.0045 0.0037 0.0138
Trichomonas vaginalis importin beta-1, putative 0.0022 0.0008 0.01
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.7689 1 1
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0108 0.012 0.2347
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0079 0.0082 0.0192
Echinococcus multilocularis Niemann Pick C1 protein 0.0131 0.015 0.035
Schistosoma mansoni alpha-1 adrenergic receptor 0.0079 0.0082 0.0322
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.0012 0.0068
Loa Loa (eye worm) hypothetical protein 0.0044 0.0036 0.0134
Trichomonas vaginalis CMGC family protein kinase 0.0029 0.0017 0.0452
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0039
Toxoplasma gondii hypothetical protein 0.0037 0.0027 0.0128
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.198 0.2559 1
Echinococcus multilocularis serotonin receptor 0.0079 0.0082 0.0192
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0108 0.012 0.0101
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0018 0.0003 0.0011
Echinococcus multilocularis dynactin 5 p25 0.0037 0.0027 0.0063
Brugia malayi G protein-coupled receptor 0.0079 0.0082 0.0315
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0138 0.0159 0.0371
Brugia malayi hypothetical protein 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0108 0.012 0.2901
Echinococcus multilocularis rhodopsin orphan GPCR 0.0079 0.0082 0.0192
Schistosoma mansoni amine GPCR 0.0079 0.0082 0.0322
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0079 0.0082 0.0322
Echinococcus multilocularis neuropeptide receptor 0.0079 0.0082 0.0192
Loa Loa (eye worm) hypothetical protein 0.0054 0.0049 0.0184
Schistosoma mansoni cercarial elastase (S01 family) 0.0261 0.0319 0.1245
Onchocerca volvulus 0.0075 0.0076 0.0267
Mycobacterium ulcerans hypothetical protein 0.1345 0.1732 0.1722
Echinococcus multilocularis neurogenic locus notch protein 4 0.0177 0.021 0.049
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.0082 0.0466
Schistosoma mansoni lipoxygenase 0.0031 0.002 0.0078
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0016
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0002 0.0005
Echinococcus multilocularis thyroid hormone receptor alpha 0.0054 0.0049 0.0114
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.0067 0.0048
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Echinococcus granulosus g-protein coupled receptor 0.0079 0.0082 0.0466
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.0012 0.0028
Echinococcus granulosus dynactin 5 p25 0.0037 0.0027 0.0152
Loa Loa (eye worm) beta-lactamase 0.0075 0.0076 0.0291
Brugia malayi hypothetical protein 0.0097 0.0106 0.0406
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0037 0.0027 0.045
Brugia malayi Calcium binding EGF domain containing protein 0.0177 0.021 0.0815
Plasmodium vivax importin-beta 2, putative 0.0027 0.0014 0.0189
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0079 0.0082 0.0466
Schistosoma mansoni cercarial elastase (S01 family) 0.0261 0.0319 0.1245
Entamoeba histolytica hypothetical protein 0.004 0.0031 0.2757
Onchocerca volvulus 0.0079 0.0082 0.029
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0108 0.012 0.0279
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0039
Brugia malayi Trypsin family protein 0.0261 0.0319 0.1238
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0395 0.0494 0.1925
Brugia malayi conserved hypotetical protein 0.0025 0.0012 0.0039
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0029 0.0017 0.0058
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0032 0.0563
Onchocerca volvulus Slit protein homolog 0.0177 0.021 0.0792
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0177 0.021 0.0792
Echinococcus granulosus rhodopsin orphan GPCR 0.0079 0.0082 0.0466
Schistosoma mansoni hypothetical protein 0.0079 0.0082 0.0322
Schistosoma mansoni neuropeptide f receptor 76f 0.0079 0.0082 0.0322
Echinococcus granulosus lamin 0.0045 0.0037 0.0211
Loa Loa (eye worm) hypothetical protein 0.0177 0.021 0.0815
Loa Loa (eye worm) melatonin receptor type 1A 0.0079 0.0082 0.0315
Loa Loa (eye worm) G-protein coupled receptor 0.0079 0.0082 0.0315
Brugia malayi putative neuropeptide receptor NPR1 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0028 0.0016 0.0055
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0108 0.012 0.0468
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0261 0.0319 0.1245
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0012 0.0068
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0032 0.016
Brugia malayi Muscle positioning protein 4 0.0177 0.021 0.0815
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0012 0.0014
Echinococcus granulosus neuropeptide receptor 0.0079 0.0082 0.0466
Brugia malayi Niemann-Pick C1 protein precursor 0.0092 0.0099 0.0378
Schistosoma mansoni cercarial elastase (S01 family) 0.0261 0.0319 0.1245
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0032 0.1049
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0039 0.003 0.0111
Mycobacterium tuberculosis Conserved protein 0.0075 0.0076 0.0058
Brugia malayi Latrophilin receptor protein 2 0.0138 0.0159 0.0615
Schistosoma mansoni cercarial elastase (S01 family) 0.0261 0.0319 0.1245
Echinococcus granulosus Tolloid protein 1 0.0465 0.0585 0.3305
Echinococcus multilocularis mannose 1 phosphate guanyltransferase 0.0038 0.0028 0.0066
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.0049 0.0184
Schistosoma mansoni lamin 0.0045 0.0037 0.0146
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0045 0.0038 0.0141
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0012 0.0039
Mycobacterium tuberculosis Possible transferase 0.0037 0.0027 0.0008
Onchocerca volvulus 0.0079 0.0082 0.029
Brugia malayi larval opioid receptor 0.0079 0.0082 0.0315
Loa Loa (eye worm) notch protein 0.0177 0.021 0.0815
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.003 0.0019 0.008
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0261 0.0319 0.1245
Schistosoma mansoni hypothetical protein 0.0395 0.0494 0.1931
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0075 0.0076 0.0291
Schistosoma mansoni notch 0.0177 0.021 0.0822
Mycobacterium tuberculosis Probable hydrolase 0.0075 0.0076 0.0058
Echinococcus granulosus glycoprotein Antigen 5 0.0261 0.0319 0.18
Echinococcus granulosus somatostatin receptor 0.0079 0.0082 0.0466
Echinococcus granulosus GPCR family 2 0.0138 0.0159 0.09
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0002 0.0011
Schistosoma mansoni hypothetical protein 0.0261 0.0319 0.1245
Brugia malayi putative neuropeptide receptor 0.0079 0.0082 0.0315
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0028 0.0016 0.0066
Onchocerca volvulus Neurogenic locus notch homolog 0.0177 0.021 0.0792
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0437 0.0549 0.2138
Loa Loa (eye worm) steroid hormone receptor 0.0054 0.0049 0.0184
Plasmodium vivax SET domain protein, putative 0.0028 0.0016 0.0231
Echinococcus granulosus protein jagged 1 0.0177 0.021 0.1188
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0044 0.0036 0.0203
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0012 0.0068
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0039
Onchocerca volvulus 0.0395 0.0494 0.1905
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Giardia lamblia High cysteine protein 0.0177 0.021 1
Echinococcus granulosus neuropeptide receptor A26 0.1375 0.1771 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0075 0.0076 0.0058
Loa Loa (eye worm) neuropeptide F receptor 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0022 0.0007 0.002
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0039
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0046 0.1554
Brugia malayi nuclear receptor NHR-88 0.0025 0.0012 0.0039
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0029 0.0017 0.03
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0054 0.0049 0.0114
Brugia malayi hypothetical protein 0.106 0.136 0.531
Schistosoma mansoni steroid hormone receptor ad4bp 0.0054 0.0049 0.0191
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0138 0.0159 0.0615
Echinococcus multilocularis solute carrier family 5 0.0042 0.0034 0.008
Schistosoma mansoni chromobox protein 0.0051 0.0046 0.0179
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Entamoeba histolytica hypothetical protein 0.0022 0.0008 0.028
Brugia malayi EGF-like domain containing protein 0.0177 0.021 0.0815
Brugia malayi ORL1-like opioid receptor 0.0079 0.0082 0.0315
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0261 0.0319 0.0743
Schistosoma mansoni hypothetical protein 0.0044 0.0036 0.014
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0012 0.0039
Schistosoma mansoni smad1 5 8 and 0.0018 0.0002 0.0008
Schistosoma mansoni gamma-secretase subunit aph-1 0.0831 0.1062 0.4147
Echinococcus granulosus muscleblind protein 0.011 0.0122 0.0689
Schistosoma mansoni cercarial elastase (S01 family) 0.0261 0.0319 0.1245
Echinococcus multilocularis cpg binding protein 0.0032 0.0021 0.0049
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0098 0.0228
Loa Loa (eye worm) hypothetical protein 0.0028 0.0016 0.0055
Schistosoma mansoni neuropeptide receptor 0.0079 0.0082 0.0322
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0108 0.012 0.0279
Echinococcus granulosus neuropeptides capa receptor 0.0079 0.0082 0.0466
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0054 0.0049 0.0184
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Brugia malayi hypothetical protein 0.0037 0.0027 0.0098
Schistosoma mansoni hypothetical protein 0.0299 0.0369 0.144
Schistosoma mansoni hypothetical protein 0.0138 0.0159 0.0623
Loa Loa (eye worm) hypothetical protein 0.0222 0.0268 0.104
Brugia malayi hypothetical protein 0.0079 0.0082 0.0315
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0108 0.012 0.0462
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0027 0.045
Echinococcus granulosus smad 0.0018 0.0002 0.0011
Trypanosoma brucei importin beta-1 subunit, putative 0.0027 0.0014 0.0234
Schistosoma mansoni growth hormone secretagogue receptor 0.0079 0.0082 0.0322
Brugia malayi Serotonin receptor 0.0079 0.0082 0.0315
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0076 0.2723
Schistosoma mansoni hypothetical protein 0.0038 0.0029 0.0112
Loa Loa (eye worm) hypothetical protein 0.0079 0.0082 0.0315
Treponema pallidum licC protein (licC) 0.1345 0.1732 1

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 21 nM Binding affinity for rat histamine H3 receptor on rat cortical cells ChEMBL. 14741266
Ki (binding) = 21 nM Binding affinity for rat histamine H3 receptor on rat cortical cells ChEMBL. 14741266
Ki (binding) = 130 nM Binding affinity for human histamine H3 receptor on human colon cells ChEMBL. 14741266
Ki (binding) = 130 nM Binding affinity for human histamine H3 receptor on human colon cells ChEMBL. 14741266

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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