Detailed information for compound 28670

Basic information

Technical information
  • TDR Targets ID: 28670
  • Name: (3,5-dimethylphenyl)methyl (2S)-2-amino-3-(1H -indol-3-yl)propanoate
  • MW: 322.401 | Formula: C20H22N2O2
  • H donors: 2 H acceptors: 1 LogP: 3.55 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C([C@H](Cc1c[nH]c2c1cccc2)N)OCc1cc(C)cc(c1)C
  • InChi: 1S/C20H22N2O2/c1-13-7-14(2)9-15(8-13)12-24-20(23)18(21)10-16-11-22-19-6-4-3-5-17(16)19/h3-9,11,18,22H,10,12,21H2,1-2H3/t18-/m0/s1
  • InChiKey: RGUDXLHTEUZZSX-SFHVURJKSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid (3,5-dimethylphenyl)methyl ester
  • (3,5-dimethylphenyl)methyl (2S)-2-azanyl-3-(1H-indol-3-yl)propanoate
  • (2S)-2-amino-3-(1H-indol-3-yl)propionic acid (3,5-dimethylbenzyl) ester

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens tachykinin receptor 1 Starlite/ChEMBL References
Homo sapiens tachykinin receptor 2 Starlite/ChEMBL References
Homo sapiens tachykinin receptor 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus tachykinin peptides receptor 99D Get druggable targets OG5_131969 All targets in OG5_131969
Echinococcus multilocularis tachykinin peptides receptor 99D Get druggable targets OG5_131969 All targets in OG5_131969
Schistosoma japonicum ko:K04224 tachykinin receptor 3, putative Get druggable targets OG5_137770 All targets in OG5_137770
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Cathepsin L-like precursor 0.0126 0.0495 0.0961
Giardia lamblia Cathepsin B precursor 0.0099 0.0343 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase BAP1 0.006 0.0119 0.023
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0524 0.2755 0.6259
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0213 0.0988 0.6069
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0043 0.002 0.002
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0304 0.1508 0.347
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trypanosoma cruzi cysteine peptidase, putative 0.0323 0.1616 0.3719
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.008 0.0232 0.1424
Schistosoma mansoni cathepsin F (C01 family) 0.0186 0.0833 0.1615
Entamoeba histolytica cysteine protease, putative 0.0099 0.0338 0.2467
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0554 0.2926 0.6661
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0101 0.0352 0.0682
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0071 0.018 0.0349
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0304 0.1508 0.347
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0047 0.0046 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0213 0.0988 0.6069
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0064 0.014 0.0857
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Schistosoma mansoni hypothetical protein 0.0213 0.0988 0.1916
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Leishmania major receptor-type adenylate cyclase a-like protein 0.0261 0.1262 0.2745
Trypanosoma cruzi major cysteine proteinase, putative 0.0177 0.0783 0.1802
Trypanosoma brucei hypothetical protein 0.0468 0.2436 0.5508
Entamoeba histolytica hypothetical protein 0.006 0.0119 0.0866
Brugia malayi calpain 7 0.03 0.1483 0.2876
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0099 0.0338 0.2074
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0043 0.002 0.002
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0226 0.1064 0.2449
Schistosoma mansoni tyrosine kinase 0.043 0.2224 0.4313
Entamoeba histolytica hypothetical protein 0.0043 0.002 0.0147
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0047 0.0046 0.0089
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0063 0.0134 0.026
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0101 0.0352 0.0601
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0076 0.0209 0.0405
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0323 0.1616 0.3577
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Brugia malayi cathepsin B-like cysteine proteinase 0.0099 0.0343 0.0665
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0474 0.2473 0.5693
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.002 0.0039
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0039
Leishmania major small myristoylated protein-2 0.0692 0.3711 0.8509
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0226 0.1064 0.2278
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0213 0.0988 0.6069
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.002 0.0147
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0047 0.0046 0.0089
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.002 0.0147
Trypanosoma cruzi cysteine peptidase, putative 0.0323 0.1616 0.3719
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0043 0.002 0.0039
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0069 0.017 0.496
Entamoeba histolytica cysteine proteinase, putative 0.0099 0.0338 0.2467
Leishmania major hypothetical protein, conserved 0.0261 0.1262 0.2745
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0391 0.2003 0.461
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0069 0.017 0.017
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0261 0.1262 0.2905
Schistosoma mansoni otubain-1 (C65 family) 0.0084 0.0253 0.0491
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.002 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0209 0.1282
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0071 0.018 0.0415
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0803 0.4345 1
Schistosoma mansoni cathepsin s 0.0059 0.0115 0.0223
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0226 0.1064 0.2278
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0043 0.002 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0047 0.0046 0.0281
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0069 0.017 0.033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0186 0.0833 0.5116
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0078 0.0221 0.0428
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Leishmania major cysteine peptidase A (CPA) 0.0186 0.0833 0.1734
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0597 0.3169 0.7233
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0128 0.0506 0.3111
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0186 0.0833 0.5116
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0063 0.0134 0.026
Trichomonas vaginalis calpain, putative 0.0213 0.0988 0.6069
Brugia malayi Cathepsin L-like precursor 0.0186 0.0833 0.1615
Onchocerca volvulus 0.0043 0.002 0.0242
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0304 0.1508 0.347
Brugia malayi calpain family protein 1 0.0269 0.1307 0.2535
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0096 0.0325 0.0538
Plasmodium falciparum deubiquinating/deneddylating enzyme 0.011 0.0402 0.0402
Onchocerca volvulus 0.0186 0.0833 1
Plasmodium vivax vivapain-2 0.0186 0.0833 0.0833
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0255 0.1225 0.282
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0152 0.0641 0.1283
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0056 0.0098 0.0098
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Toxoplasma gondii hypothetical protein 0.0043 0.002 0.002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0075 0.0205 0.1262
Loa Loa (eye worm) hypothetical protein 0.0069 0.017 0.033
Echinococcus granulosus insulin receptor 0.0946 0.5156 1
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0047 0.0046 0.0089
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0323 0.1616 0.3577
Onchocerca volvulus 0.0186 0.0833 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0186 0.0833 0.0833
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0101 0.0352 0.0682
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0043 0.002 0.0124
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase isozyme 0.0122 0.0468 0.0908
Echinococcus granulosus cysteine protease atg4b 0.008 0.0232 0.045
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Plasmodium falciparum cysteine protease ATG4, putative 0.0045 0.0032 0.0032
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0063 0.0134 0.0309
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0304 0.1508 0.347
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.002 0.0039
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0205 0.0946 0.1999
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Echinococcus multilocularis cathepsin b 0.0099 0.0343 0.0665
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0076 0.0209 0.0405
Trypanosoma brucei small myristoylated protein 1-1 0.0407 0.2091 0.4695
Plasmodium vivax ubiquitin C-terminal hydrolase, family 1, putative 0.011 0.0402 0.0402
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.015 0.0346
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0047 0.0046 0.0281
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0063 0.0134 0.0134
Trypanosoma cruzi cysteine peptidase, putative 0.0186 0.0833 0.1917
Toxoplasma gondii exonuclease 0.0059 0.0114 0.0114
Entamoeba histolytica peptidase, C54 family 0.0045 0.0032 0.0236
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0186 0.0833 0.5116
Loa Loa (eye worm) hypothetical protein 0.0126 0.0495 0.0961
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0128 0.0506 0.1166
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0064 0.014 0.0857
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.002 0.0039
Brugia malayi Cathepsin L-like precursor 0.0126 0.0495 0.0961
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Leishmania major hypothetical protein, unknown function 0.0644 0.3437 0.7863
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0043 0.002 0.0039
Entamoeba histolytica protein kinase, putative 0.0056 0.0096 0.0702
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0186 0.0833 0.5116
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0078 0.0221 0.0428
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0101 0.0352 0.0601
Trypanosoma brucei cysteine peptidase, Clan CA, family C51, putative 0.0304 0.1508 0.3322
Trypanosoma brucei calpain-like protein, putative 0.0288 0.1414 0.3101
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0071 0.018 0.0198
Trypanosoma cruzi trypanothione synthetase-like protein, putative 0.0066 0.015 0.0346
Echinococcus multilocularis cysteine protease 0.0186 0.0833 0.1615
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0043 0.002 0.0124
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.011 0.0402 0.0924
Loa Loa (eye worm) hypothetical protein 0.0058 0.0106 0.0206
Loa Loa (eye worm) hypothetical protein 0.0059 0.0115 0.0223
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trypanosoma brucei hypothetical protein, conserved 0.0326 0.1628 0.3606
Trichomonas vaginalis Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase 0.0122 0.0468 0.2875
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.002 0.0147
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0264 0.1278 0.2942
Leishmania major small myristoylated protein-1 0.0407 0.2091 0.4695
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0354 0.1789 0.4119
Brugia malayi calpain 5 0.0213 0.0988 0.1916
Echinococcus multilocularis 0.0124 0.048 0.0931
Schistosoma mansoni Mername-AA248 (C02 family) 0.0269 0.1307 0.2535
Entamoeba histolytica cysteine proteinase, putative 0.0186 0.0833 0.6085
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0076 0.0209 0.0405
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0075 0.0205 0.0205
Onchocerca volvulus 0.0186 0.0833 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0075 0.0205 0.0398
Echinococcus multilocularis hypothetical protein 0.0269 0.1307 0.2535
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0047 0.0046 0.0089
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0288 0.1414 0.3254
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0288 0.1414 0.3254
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.002 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0056 0.0098 0.0605
Echinococcus multilocularis cathepsin b 0.0099 0.0343 0.0665
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0636 0.3393 0.7809
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0112 0.0415 0.0092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0063 0.0134 0.0824
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0075 0.0205 0.0398
Plasmodium vivax vivapain-2 0.0186 0.0833 0.0833
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0226 0.1064 0.2449
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0112 0.0414 0.0802
Leishmania major META domain containing protein 0.0261 0.1262 0.2745
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Schistosoma mansoni cathepsin F (C01 family) 0.0186 0.0833 0.1615
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Leishmania major cathepsin L-like protease 0.0186 0.0833 0.1734
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0075 0.0205 0.0205
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0043 0.002 0.0039
Brugia malayi Cathepsin L-like precursor 0.0059 0.0115 0.0223
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.002 0.0147
Trypanosoma cruzi cysteine peptidase, Clan CA, family C48, putative 0.0175 0.0774 0.1782
Schistosoma mansoni hypothetical protein 0.0043 0.002 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.002 0.0147
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0099 0.0343 0.058
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0043 0.002 0.0039
Loa Loa (eye worm) hypothetical protein 0.0126 0.0495 0.0961
Plasmodium falciparum cysteine proteinase falcipain 1 0.0099 0.0338 0.0338
Echinococcus multilocularis cathepsin L cysteine protease 0.0186 0.0833 0.1615
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0226 0.1064 0.2278
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0101 0.0352 0.0682
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0071 0.018 0.0198
Loa Loa (eye worm) ubiquitin C-terminal hydrolase UCH-L5 0.011 0.0402 0.0779
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Echinococcus multilocularis calpain A 0.0269 0.1307 0.2535
Entamoeba histolytica cysteine protease, putative 0.0099 0.0338 0.2467
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0226 0.1064 0.2449
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0186 0.0833 0.5116
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.011 0.0402 0.2934
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0261 0.1262 0.2905
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0043 0.002 0.002
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0288 0.1416 0.2273
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase isozyme L3, putative 0.0122 0.0468 0.0468
Trichomonas vaginalis calpain, putative 0.0213 0.0988 0.6069
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0354 0.1789 0.3986
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0252 0.1212 0.2625
Leishmania major small myristoylated protein 4, putative 0.0607 0.3226 0.7367
Echinococcus granulosus ubiquitin specific protease 41 0.0076 0.0209 0.0405
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0397 0.2032 0.4557
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0326 0.1628 1
Leishmania major calpain family cysteine protease-like protein 0.0541 0.2854 0.6491
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0614 0.3268 0.7521
Brugia malayi cathepsin L-like precursor 0.0126 0.0495 0.0961
Trypanosoma cruzi hypothetical protein, conserved 0.0326 0.1628 0.3747
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0063 0.0134 0.009
Toxoplasma gondii ubiquitin-specific protease USP4 0.0043 0.002 0.002
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0213 0.0988 0.21
Entamoeba histolytica cysteine proteinase, putative 0.0099 0.0338 0.2467
Toxoplasma gondii peptidase c13 family protein 0.0059 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0059 0.0115 0.0223
Schistosoma mansoni tyrosine kinase 0.043 0.2224 0.4313
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0547 0.2889 0.6573
Toxoplasma gondii cathepsin B 0.0099 0.0343 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0186 0.0833 0.5116
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0076 0.0209 0.0405
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.002 0.0147
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0226 0.1064 0.2449
Brugia malayi Papain family cysteine protease containing protein 0.0186 0.0833 0.1615
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0186 0.0833 0.1615
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Leishmania major inhibitor of cysteine peptidase 0.0228 0.1073 0.23
Echinococcus granulosus cathepsin L cysteine protease 0.0099 0.0338 0.0655
Echinococcus multilocularis epidermal growth factor receptor 0.043 0.2224 0.4313
Echinococcus multilocularis cathepsin L cysteine protease 0.0186 0.0833 0.1615
Schistosoma mansoni cathepsin F (C01 family) 0.0126 0.0495 0.0961
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0128 0.0506 0.1166
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0047 0.0046 0.0089
Trichomonas vaginalis ubiquitin specific protease, putative 0.0062 0.0127 0.0781
Loa Loa (eye worm) hypothetical protein 0.0126 0.0495 0.0961
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0128 0.0506 0.0982
Giardia lamblia GPI-anchor transamidase, putative 0.0059 0.0115 0.3365
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0043 0.002 0.002
Schistosoma mansoni ubiquitinyl hydrolase-BAP1 (C12 family) 0.006 0.0119 0.023
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0039
Brugia malayi Peptidase family C54 containing protein 0.008 0.0232 0.045
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0261 0.1262 0.2745
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0099 0.0343 0.0665
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0101 0.0352 0.0809
Trypanosoma cruzi unspecified product 0.0407 0.2091 0.4812
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0269 0.1307 0.2535
Loa Loa (eye worm) hypothetical protein 0.0122 0.0468 0.0908
Schistosoma mansoni hypothetical protein 0.0165 0.0715 0.1387
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0162 0.0697 0.1604
Trypanosoma brucei cysteine peptidase C (CPC) 0.0099 0.0343 0.058
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0803 0.4345 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.0343 0.0665
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0043 0.002 0.0039
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0059 0.0115 0.0045
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0186 0.0833 0.5116
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0071 0.018 0.0198
Trypanosoma brucei antigen, putative 0.0269 0.1307 0.285
Loa Loa (eye worm) hypothetical protein 0.0269 0.1307 0.2535
Entamoeba histolytica cysteine protease, putative 0.0099 0.0338 0.2467
Trypanosoma cruzi cysteine peptidase inhibitor, putative 0.0228 0.1073 0.2471
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0099 0.0343 0.0665
Entamoeba histolytica cysteine proteinase 2 0.0099 0.0338 0.2467
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0043 0.002 0.0039
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0043 0.002 0.002
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase isozyme L3 0.0122 0.0468 0.0468
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0071 0.018 0.0349
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.003 0.0059
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Echinococcus multilocularis calpain 5 0.0269 0.1307 0.2535
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.008 0.0232 0.045
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trypanosoma cruzi otubain cysteine peptidase, Clan CA, family C65, putative 0.0084 0.0253 0.0582
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0101 0.0352 0.0809
Loa Loa (eye worm) calpain family protein 1 0.0269 0.1307 0.2535
Loa Loa (eye worm) calpain D 0.028 0.1369 0.2655
Entamoeba histolytica cysteine protease, putative 0.0099 0.0338 0.2467
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0043 0.002 0.002
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0176 0.0778 0.5
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0803 0.4345 1
Trypanosoma cruzi pyroglutamyl-peptidase I, putative 0.0419 0.216 0.4972
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Leishmania major hypothetical protein, conserved 0.0261 0.1262 0.2745
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0226 0.1064 0.2449
Trypanosoma brucei inhibitor of cysteine peptidase 0.0228 0.1073 0.23
Onchocerca volvulus Cathepsin L homolog 0.0186 0.0833 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0069 0.017 0.033
Echinococcus granulosus GPI anchor transamidase 0.0059 0.0115 0.0224
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0226 0.1064 0.2278
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0468 0.2436 0.5508
Trypanosoma cruzi cysteine peptidase, putative 0.0323 0.1616 0.3719
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0099 0.0343 0.0789
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0391 0.2003 0.461
Trichomonas vaginalis ubiquitin specific protease, putative 0.0043 0.002 0.0124
Echinococcus granulosus cathepsin l1 0.0186 0.0833 0.1615
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.002 0.0147
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.002 0.0039
Echinococcus granulosus calpain 5 0.0269 0.1307 0.2535
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0063 0.0134 0.0134
Leishmania major cathepsin L-like protease 0.0186 0.0833 0.1734
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0063 0.0134 0.0824
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0099 0.0338 0.0655
Onchocerca volvulus 0.0186 0.0833 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0096 0.0325 0.063
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0069 0.017 0.017
Plasmodium vivax vivapain-1 0.0099 0.0338 0.0338
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0043 0.002 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Loa Loa (eye worm) ctsf protein 0.0186 0.0833 0.1615
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0323 0.1616 0.3577
Loa Loa (eye worm) hypothetical protein 0.0059 0.0115 0.0224
Trichomonas vaginalis hypothetical protein 0.0213 0.0988 0.6069
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0043 0.002 0.0039
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0101 0.0352 0.0682
Plasmodium falciparum cysteine proteinase falcipain 3 0.0186 0.0833 0.0833
Leishmania major hypothetical protein, conserved 0.0423 0.218 0.4904
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.008 0.0232 0.045
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0063 0.0134 0.026
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0583 0.309 0.7113
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.003 0.0059
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0071 0.018 0.0349
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0076 0.0209 0.0265
Trypanosoma cruzi hypothetical protein, conserved 0.0261 0.1262 0.2905
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0043 0.002 0.0039
Echinococcus granulosus cathepsin l1 0.0126 0.0495 0.0961
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.003 0.0059
Trypanosoma brucei trypanothione synthetase 0.0066 0.015 0.0128
Leishmania major hypothetical protein, conserved 0.0326 0.1628 0.3606
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0126 0.0495 0.3042
Trypanosoma brucei calpain-like protein, putative 0.0269 0.1307 0.285
Echinococcus granulosus Peptidase C54 0.008 0.0232 0.045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0323 0.1616 0.3577
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0043 0.002 0.0039
Echinococcus multilocularis calpain 7 (C02 family) 0.03 0.1483 0.2876
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0261 0.1262 0.2745
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0071 0.018 0.0349
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0043 0.002 0.0039
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0554 0.2926 0.6735
Leishmania major hypothetical protein, conserved 0.0261 0.1262 0.2745
Brugia malayi ubiquitin specific protease 14 0.0069 0.017 0.033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0323 0.1616 0.3577
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0099 0.0338 0.2074
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0063 0.0134 0.026
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0047 0.0046 0.0089
Trypanosoma brucei calpain, putative 0.0213 0.0988 0.21
Entamoeba histolytica cysteine protease inhibitor 1 (EhICP1) 0.0228 0.1073 0.7842
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0096 0.0325 0.0538
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0323 0.1616 0.3577
Loa Loa (eye worm) hypothetical protein 0.0213 0.0988 0.1916
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0397 0.2032 0.4677
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0039
Trypanosoma brucei Calpain-like protein CALP1.3 0.0474 0.2473 0.5595
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0186 0.0833 0.5116
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.011 0.0402 0.0779
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Echinococcus multilocularis insulin receptor 0.0946 0.5156 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0039
Leishmania major D-alanyl-glycyl endopeptidase-like protein,cysteine peptidase, Clan CA, family C51, putative 0.0304 0.1508 0.3322
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0099 0.0338 0.0568
Onchocerca volvulus 0.0043 0.002 0.0242
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0069 0.017 0.0174
Plasmodium vivax vivapain-3 0.0099 0.0338 0.0338
Echinococcus granulosus cathepsin L cysteine proteinase 0.0186 0.0833 0.1615
Trichomonas vaginalis Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase 0.0122 0.0468 0.2875
Giardia lamblia Cathepsin B precursor 0.0099 0.0343 1
Entamoeba histolytica cysteine proteinase, putative 0.0099 0.0338 0.2467
Entamoeba histolytica cysteine protease, putative 0.0099 0.0338 0.2467
Echinococcus multilocularis expressed protein 0.0043 0.002 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0128 0.0506 0.0982
Entamoeba histolytica cysteine proteinase, putative 0.0099 0.0338 0.2467
Brugia malayi calpain 5 0.0056 0.0096 0.0186
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0261 0.1262 0.2745
Trypanosoma cruzi small myristoylated protein 1-1 0.0407 0.2091 0.4812
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0186 0.0833 0.5116
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0043 0.002 0.002
Onchocerca volvulus 0.0186 0.0833 1
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0255 0.1225 0.2658
Schistosoma mansoni tyrosine kinase 0.0423 0.2181 0.4229
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0122 0.0468 0.0908
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0069 0.017 0.033
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.002 0.0147
Echinococcus multilocularis cysteine protease atg4b 0.008 0.0232 0.045
Trypanosoma brucei small myristoylated protein 1-2 0.0407 0.2091 0.4695
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.011 0.0402 0.0779
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0209 0.048
Entamoeba histolytica cysteine protease, putative 0.0099 0.0338 0.2467
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0078 0.0221 0.0221
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0099 0.0343 0.2105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Entamoeba histolytica cysteine protease, putative 0.0099 0.0338 0.2467
Trypanosoma brucei Calpain-like protein 1.2 0.0614 0.3268 0.7465
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0261 0.1262 0.2745
Toxoplasma gondii chorismate synthase, putative 0.1798 1 1
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0043 0.002 0.002
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0205 0.0946 0.1999
Trypanosoma cruzi glutathionylspermidine synthase, putative 0.0066 0.015 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0524 0.2755 0.6341
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0554 0.2926 0.6735
Entamoeba histolytica peptidase, C54 family 0.0191 0.0861 0.6288
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0614 0.3268 0.7465
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0213 0.0988 0.6069
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0186 0.0833 0.5116
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0252 0.1212 0.2625
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0323 0.1616 0.3577
Leishmania major hypothetical protein, conserved 0.0066 0.015 0.0128
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0099 0.0338 0.0655
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0186 0.0833 0.5116
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0397 0.2032 0.4557
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0047 0.0046 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0069 0.017 0.0391
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0047 0.0046 0.0046
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0354 0.1789 0.4119
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0269 0.1307 0.2535
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0524 0.2755 0.6341
Brugia malayi GPI-anchor transamidase 0.0059 0.0115 0.0224
Trypanosoma brucei calpain-like protein, putative 0.0524 0.2755 0.6259
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.002 0.0039
Leishmania major SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative 0.0175 0.0774 0.1596
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0524 0.2755 0.6259
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0288 0.1416 0.1416
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0047 0.0046 0.0089
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0076 0.0209 0.0405
Echinococcus multilocularis GPI anchor transamidase 0.0059 0.0115 0.0224
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0059 0.0114 0.0262
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0099 0.0343 0.0665
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0056 0.0098 0.0098
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0323 0.1616 0.3577
Echinococcus granulosus Ubiquitin thioesterase otubain protein 0.0084 0.0253 0.0491
Schistosoma mansoni ubiquitinyl hydrolase-UCH37 (C12 family) 0.011 0.0402 0.0779
Leishmania major hypothetical protein, conserved 0.0261 0.1262 0.2745
Echinococcus multilocularis calpain 0.0269 0.1307 0.2535
Brugia malayi cathepsin F-like cysteine proteinase 0.0059 0.0115 0.0223
Giardia lamblia DUB-1 0.0043 0.002 0.0588
Trypanosoma cruzi cysteine peptidase, putative 0.0059 0.0115 0.0264
Leishmania major trypanothione synthetase, putative 0.0066 0.015 0.0128
Leishmania major cathepsin L-like protease 0.0186 0.0833 0.1734
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0099 0.0338 0.0568
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trypanosoma brucei calpain, putative 0.0468 0.2436 0.5508
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.008 0.0232 0.1424
Loa Loa (eye worm) hypothetical protein 0.0056 0.0096 0.0186
Leishmania major trypanothione synthetase, putative 0.0066 0.015 0.0128
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0069 0.017 0.0174
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0271 0.1319 0.3035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0186 0.0833 0.5116
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0078 0.0221 0.0508
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0186 0.0833 0.5116
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0946 0.5156 1
Brugia malayi Cathepsin L-like precursor 0.0186 0.0833 0.1615
Plasmodium falciparum GPI-anchor transamidase, putative 0.0059 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0039
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase UCHL3 0.0122 0.0468 0.0468
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.008 0.0232 0.0534
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trypanosoma brucei pyroglutamyl-peptidase I, putative 0.0419 0.216 0.4858
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0252 0.1212 0.2789
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0078 0.0221 0.1356
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0209 0.048
Brugia malayi ubiquitin C-terminal hydrolase UCH-L5 0.011 0.0402 0.0779
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0056 0.0098 0.0605
Brugia malayi Papain family cysteine protease containing protein 0.0099 0.0338 0.0655
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0043 0.002 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0064 0.014 0.0857
Schistosoma mansoni hypothetical protein 0.0165 0.0715 0.1387
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0039
Plasmodium falciparum ubiquitin specific protease, putative 0.0043 0.002 0.002
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0547 0.2889 0.6573
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0043 0.002 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0636 0.3393 0.776
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0076 0.0209 0.1282
Loa Loa (eye worm) hypothetical protein 0.0213 0.0988 0.1916
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0261 0.1262 0.2905
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0152 0.0641 0.1476
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0288 0.1416 0.1044
Schistosoma mansoni tyrosine kinase 0.0423 0.2181 0.4229
Entamoeba histolytica cysteine protease, putative 0.0099 0.0338 0.2467
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0122 0.0468 0.1077
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0043 0.002 0.0039
Leishmania major cathepsin L-like protease 0.0323 0.1616 0.3577
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0255 0.1225 0.2658
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0047 0.0046 0.0281
Loa Loa (eye worm) hypothetical protein 0.0069 0.017 0.033
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0043 0.002 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0261 0.1262 0.2905
Plasmodium vivax unspecified product 0.0099 0.0338 0.0338
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0186 0.0833 0.1615
Entamoeba histolytica calpain large subunit domain III containing protein 0.0056 0.0096 0.0702
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0803 0.4345 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.008 0.0232 0.1424
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0039
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0099 0.0343 0.0789
Leishmania major hypothetical protein, conserved 0.0261 0.1262 0.2745
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0096 0.0325 0.063
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.003 0.0059
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0043 0.002 0.002
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase BAP1 0.006 0.0119 0.023
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.002 0.0147
Brugia malayi Cathepsin L-like cysteine proteinase 0.0126 0.0495 0.0961
Echinococcus granulosus cathepsin b 0.0099 0.0343 0.0665
Trypanosoma brucei trypanothione synthetase, putative 0.0066 0.015 0.0128
Trypanosoma brucei cysteine peptidase, Clan CA, family C51, putative 0.0304 0.1508 0.3322
Loa Loa (eye worm) hypothetical protein 0.0065 0.0146 0.0283
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.008 0.0232 0.0319
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0191 0.0861 0.1981
Trypanosoma brucei CHAP domain containing protein, putative 0.0066 0.015 0.0128
Loa Loa (eye worm) cysteine protease 0.0186 0.0833 0.1615
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0644 0.3437 0.7863
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0468 0.2436 0.5508
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0043 0.002 0.0039
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0047 0.0046 0.0046
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0271 0.1319 0.2877
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0761 0.4106 0.9438
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0059 0.0115 0.0708
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0075 0.0205 0.1262
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0043 0.002 0.0039
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0803 0.4345 1
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0388 0.1984 0.4566
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0191 0.0861 0.1981
Entamoeba histolytica cysteine protease, putative 0.0099 0.0338 0.2467
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0474 0.2473 0.5693
Entamoeba histolytica cysteine proteinase, putative 0.0186 0.0833 0.6085
Trypanosoma cruzi small myristoylated protein 1-2 0.0407 0.2091 0.4812
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0524 0.2755 0.6341
Leishmania major cathepsin L-like protease 0.0186 0.0833 0.1734
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0099 0.0343 0.0665
Loa Loa (eye worm) hypothetical protein 0.013 0.0516 0.1001
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0043 0.002 0.0039
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0043 0.002 0.0039
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.002 0.0147
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0075 0.0205 0.599
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0186 0.0833 0.5116
Leishmania major otubain, putative,otubain cysteine peptidase, Clan CA, family C65, putative 0.0084 0.0253 0.0369
Leishmania major ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative 0.011 0.0402 0.0719
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0186 0.0833 0.1615
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0069 0.017 0.017
Echinococcus multilocularis cysteine protease 0.0186 0.0833 0.1615
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Entamoeba histolytica cysteine protease, putative 0.0099 0.0338 0.2467
Plasmodium vivax chorismate synthase 0.1798 1 1
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0255 0.1225 0.2658
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Brugia malayi Papain family cysteine protease containing protein 0.0099 0.0338 0.0655
Brugia malayi Protein kinase domain containing protein 0.0946 0.5156 1
Echinococcus multilocularis ubiquitin specific protease 41 0.0076 0.0209 0.0405
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0323 0.1616 0.3577
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0047 0.0046 0.0089
Trypanosoma cruzi trypanothione synthetase, putative 0.0066 0.015 0.0346
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.011 0.0402 0.0924
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0069 0.017 0.033
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0043 0.002 0.002
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0354 0.1789 0.4119
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0186 0.0833 0.5116
Onchocerca volvulus 0.0186 0.0833 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0524 0.2755 0.6341
Trypanosoma cruzi cruzipain precursor, putative 0.0059 0.0115 0.0264
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0122 0.0468 0.0908
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0043 0.002 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.003 0.0059
Trypanosoma cruzi cysteine proteinase, putative 0.0099 0.0338 0.0777
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0059 0.0114 0.0041
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0614 0.3268 0.7521
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase isozyme 0.011 0.0402 0.0779
Brugia malayi Protein kinase domain containing protein 0.0523 0.2753 0.5339
Leishmania major cathepsin L-like protease 0.0323 0.1616 0.3577
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0524 0.2755 0.6259
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.002 0.0147
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0209 0.0265
Trypanosoma cruzi cysteine peptidase, putative 0.0099 0.0338 0.0777
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0288 0.1416 0.1127
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.008 0.0232 0.1424
Brugia malayi Ubiquitin carboxyl-terminal hydrolase, family 1 protein 0.0122 0.0468 0.0908
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0059 0.0115 0.0223
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0176 0.0778 0.5
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0128 0.0506 0.3111
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0096 0.0325 0.063
Trypanosoma brucei calpain-like protein, putative 0.0288 0.1414 0.3101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trypanosoma brucei otubain cysteine peptidase, Clan CA, family C65, putative 0.0084 0.0253 0.0369
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0043 0.002 0.0039
Echinococcus granulosus calpain 7 C02 family 0.03 0.1483 0.2876
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0096 0.0325 0.0748
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0186 0.0833 0.5116
Loa Loa (eye worm) calpain family protein 1 0.0213 0.0988 0.1916
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase, family 1 protein 0.011 0.0402 0.0402
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.043 0.2224 0.4313
Schistosoma mansoni tyrosine kinase 0.0946 0.5156 1
Trypanosoma cruzi kinesin, putative 0.0056 0.0096 0.0221
Entamoeba histolytica cysteine protease, putative 0.0099 0.0338 0.2467
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0096 0.0325 0.063
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.002 0.0147
Entamoeba histolytica cysteine proteinase, putative 0.0126 0.0495 0.3618
Loa Loa (eye worm) hypothetical protein 0.0242 0.1153 0.2235
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.006 0.0119 0.0053
Onchocerca volvulus 0.0043 0.002 0.0242
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0101 0.0352 0.0682
Echinococcus granulosus geminin 0.0165 0.0715 0.1387
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0071 0.018 0.1107
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Echinococcus granulosus cysteine protease 0.0099 0.0338 0.0655
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) 0.0887 0.4818 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Leishmania major cathepsin L-like protease 0.0323 0.1616 0.3577
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0063 0.0134 0.0981
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Echinococcus multilocularis Ubiquitin thioesterase otubain protein 0.0084 0.0253 0.0491
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.002 0.0039
Plasmodium vivax unspecified product 0.0059 0.0115 0.0115
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0043 0.002 0.0124
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.008 0.0232 0.0319
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0045 0.0032 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0232 0.1095 0.1095
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0063 0.0134 0.026
Plasmodium falciparum calpain 0.0232 0.1095 0.1095
Loa Loa (eye worm) fibroinase 0.0186 0.0833 0.1615
Echinococcus granulosus calpain 0.0269 0.1307 0.2535
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0077 0.0218 0.0218
Echinococcus granulosus calpain A 0.0269 0.1307 0.2535
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.003 0.0059
Loa Loa (eye worm) calpain 0.03 0.1483 0.2876
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Giardia lamblia Hypothetical protein 0.0047 0.0046 0.1337
Brugia malayi calpain D 0.028 0.1369 0.2655
Brugia malayi hypothetical protein 0.0043 0.002 0.0039
Brugia malayi Furin-like cysteine rich region family protein 0.043 0.2224 0.4313
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0073 0.0195 0.0378
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0397 0.2032 0.4677
Toxoplasma gondii hypothetical protein 0.0213 0.0988 0.0988
Trypanosoma cruzi trypanothione synthetase 0.0066 0.015 0.0346
Echinococcus multilocularis Peptidase C54 0.008 0.0232 0.045
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trypanosoma cruzi cruzipain precursor, putative 0.0323 0.1616 0.3719
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0047 0.0046 0.0089
Plasmodium vivax ubiquitin specific protease, putative 0.0043 0.002 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0186 0.0833 0.5116
Trypanosoma cruzi trypanothione synthetase 0.0066 0.015 0.0346
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0354 0.1789 0.3986
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0186 0.0833 0.5116
Loa Loa (eye worm) calpain 5 0.0056 0.0096 0.0186
Leishmania major cathepsin L-like protease 0.0186 0.0833 0.1734
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0453 0.2351 0.5411
Echinococcus multilocularis epidermal growth factor receptor 0.043 0.2224 0.4313
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0761 0.4106 0.9438
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Schistosoma mansoni tyrosine kinase 0.0946 0.5156 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.0186 0.0833 0.1615
Trichomonas vaginalis calpain, putative 0.0213 0.0988 0.6069
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.002 0.0039
Leishmania major PFPI/DJ-1-like protein, putative 0.044 0.2278 0.5136
Brugia malayi Cathepsin L-like precursor 0.0186 0.0833 0.1615
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.002 0.0147
Loa Loa (eye worm) hypothetical protein 0.0186 0.0833 0.1615
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Schistosoma mansoni calpain-7 (C02 family) 0.0343 0.1726 0.3347
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0213 0.0988 0.6069
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0043 0.002 0.0039
Schistosoma mansoni ubiquitinyl hydrolase-UCH37 (C12 family) 0.011 0.0402 0.0779
Schistosoma mansoni calpain C (C02 family) 0.0269 0.1307 0.2535
Entamoeba histolytica GPI-anchor transamidase, putative 0.0059 0.0115 0.0843
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0304 0.1508 0.347
Loa Loa (eye worm) TK/EGFR protein kinase 0.043 0.2224 0.4313
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0043 0.002 0.0039
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0039
Schistosoma mansoni tyrosine kinase 0.043 0.2224 0.4313
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0583 0.309 0.7113
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0176 0.0778 0.0379
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0269 0.1307 0.2535
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0186 0.0833 0.5116
Schistosoma mansoni calpain-7 (C02 family) 0.0343 0.1726 0.3347
Entamoeba histolytica calpain family cysteine protease, putative 0.028 0.1369 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0075 0.0205 0.0398
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Echinococcus granulosus epidermal growth factor receptor 0.043 0.2224 0.4313
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0803 0.4345 1
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0946 0.5156 1
Schistosoma mansoni tyrosine kinase 0.0423 0.2181 0.4229
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0063 0.0134 0.009
Trypanosoma cruzi Cysteine peptidase, Clan CF, family C15 0.0419 0.216 0.4972
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Entamoeba histolytica cysteine proteinase 1, putative 0.0099 0.0338 0.2467
Onchocerca volvulus 0.0186 0.0833 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0323 0.1616 0.3577
Echinococcus granulosus ubiquitin specific peptidase c family 0.0128 0.0506 0.0982
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0391 0.2003 0.4488
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0607 0.3226 0.7425
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0186 0.0833 0.5116
Trypanosoma cruzi cysteine proteinase, putative 0.0099 0.0338 0.0777
Brugia malayi calpain family protein 1 0.0269 0.1307 0.2535
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0043 0.002 0.0039
Brugia malayi Cathepsin L-like precursor 0.0186 0.0833 0.1615
Trypanosoma brucei Calpain-like protein 2 0.0597 0.3169 0.7233
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0261 0.1262 0.2745
Entamoeba histolytica cysteine protease inhibitor 2 (EhICP2) 0.0228 0.1073 0.7842
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0059 0.0115 0.0223
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0076 0.0209 0.0405
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0335 0.1684 0.3876
Loa Loa (eye worm) hypothetical protein 0.0084 0.0253 0.0491
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0269 0.1307 0.2535
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Leishmania major small myristoylated protein-3, putative 0.0354 0.1789 0.3986
Entamoeba histolytica cysteine protease, putative 0.0099 0.0338 0.2467
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Onchocerca volvulus Cathepsin F homolog 0.0186 0.0833 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0043 0.002 0.0588
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0226 0.1064 0.2449
Plasmodium vivax calpain, putative 0.0288 0.1414 0.1414
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0043 0.002 0.0039
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0226 0.1064 0.2278
Brugia malayi CG8232-PA 0.0058 0.0106 0.0206
Trypanosoma cruzi hypothetical protein, conserved 0.0261 0.1262 0.2905
Loa Loa (eye worm) hypothetical protein 0.0516 0.2709 0.5255
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0043 0.002 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0186 0.0833 0.5116
Leishmania major D-alanyl-glycyl endopeptidase-like protein,cysteine peptidase, Clan CA, family C51, putative 0.0304 0.1508 0.3322
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0453 0.2351 0.5411
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.059 0.3134 0.7213
Schistosoma mansoni calpain (C02 family) 0.0269 0.1307 0.2535
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0099 0.0338 0.0777
Trypanosoma cruzi cysteine peptidase inhibitor 0.0228 0.1073 0.2471
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trypanosoma brucei conserved protein 0.021 0.0969 0.2054
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.003 0.0059
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0076 0.0209 0.1525
Leishmania major hypothetical protein, conserved 0.0261 0.1262 0.2745
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0059 0.0115 0.0045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0323 0.1616 0.3577
Giardia lamblia Cathepsin B precursor 0.0099 0.0343 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.002 0.0147
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0043 0.002 0.002
Echinococcus granulosus cathepsin b 0.0099 0.0343 0.0665
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0186 0.0833 0.5116
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0644 0.3437 0.7863
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0063 0.0134 0.026
Plasmodium vivax hypothetical protein, conserved 0.0063 0.0134 0.0134
Schistosoma mansoni autophagin-1 (C54 family) 0.008 0.0232 0.045
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0047 0.0046 0.0335
Schistosoma mansoni calpain-2 (C02 family) 0.0213 0.0988 0.1916
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0257 0.1237 0.2686
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0039
Loa Loa (eye worm) TK/INSR protein kinase 0.0946 0.5156 1
Trypanosoma brucei amidase, putative 0.0066 0.015 0.0128
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0078 0.0221 0.1612
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.002 0.0147
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0176 0.0778 0.0468
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0554 0.2926 0.6661
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Echinococcus granulosus calpain A 0.0269 0.1307 0.2535
Leishmania major ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative 0.0122 0.0468 0.0876
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0059 0.0115 0.0708
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0043 0.002 0.0039
Trypanosoma cruzi cysteine protease, putative 0.0099 0.0338 0.0777
Echinococcus granulosus epidermal growth factor receptor 0.043 0.2224 0.4313
Loa Loa (eye worm) hypothetical protein 0.0076 0.0209 0.0405
Mycobacterium ulcerans chorismate synthase 0.1798 1 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.002 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0126 0.0495 0.3042
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0186 0.0833 0.5116
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0152 0.0641 0.4685
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0252 0.1212 0.2789
Entamoeba histolytica peptidase, C54 family 0.0045 0.0032 0.0236
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0152 0.0641 0.1476
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0307 0.1522 0.2953
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0099 0.0338 0.0655
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0761 0.4106 0.9438
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0073 0.0195 0.0449
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0366 0.1857 0.3601
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0191 0.0861 0.18
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0043 0.002 0.0039
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0226 0.1064 0.2278
Loa Loa (eye worm) cathepsin B 0.0099 0.0343 0.0665
Trypanosoma brucei unspecified product 0.0261 0.1262 0.2745
Trypanosoma brucei glutathionylspermidine synthetase, putative 0.0066 0.015 0.0128
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0099 0.0343 0.0665
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0186 0.0833 0.5116
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0076 0.0209 0.1282
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0583 0.309 0.7047
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0636 0.3393 0.7809
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0122 0.0468 0.0908
Echinococcus granulosus tachykinin peptides receptor 99D 0.0366 0.1857 0.3601
Leishmania major pyroglutamyl-peptidase I (C15 family) 0.0419 0.216 0.4858
Trypanosoma cruzi conserved protein 0.0423 0.218 0.5017
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.002 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0326 0.1628 0.3747
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0069 0.017 0.1044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Toxoplasma gondii ubiquitin thioesterase otubain-like family protein 0.0084 0.0253 0.0253
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0071 0.018 0.0349
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Onchocerca volvulus 0.0126 0.0495 0.5946
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0474 0.2473 0.5693
Trypanosoma cruzi trypanothione synthetase, putative 0.0066 0.015 0.0346
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0128 0.0506 0.37
Trypanosoma cruzi kinesin, putative 0.0056 0.0096 0.0221
Echinococcus multilocularis geminin 0.0165 0.0715 0.1387
Trypanosoma cruzi hypothetical protein, conserved 0.0261 0.1262 0.2905
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0075 0.0205 0.0398
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis ubiquitin specific protease, putative 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0186 0.0833 0.1615
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.002 0.0124
Trypanosoma cruzi otubain cysteine peptidase, Clan CA, family C65, putative 0.0084 0.0253 0.0582
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0255 0.1225 0.2658
Entamoeba histolytica peptidase, C54 family 0.008 0.0232 0.1694
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0076 0.0209 0.6089
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.003 0.0059
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.003 0.0059
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0096 0.0325 0.063
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0078 0.0221 0.0293
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0078 0.0221 0.0293
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.008 0.0232 0.1424
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0059 0.0115 0.0224
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0186 0.0833 0.0833
Entamoeba histolytica cysteine protease, putative 0.0186 0.0833 0.6085
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0043 0.002 0.0039
Plasmodium vivax GPI-anchor transamidase, putative 0.0059 0.0115 0.0115
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0128 0.0506 0.0966
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0047 0.0046 0.0089
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0205 0.0946 0.2176
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0191 0.0861 0.18
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0152 0.0641 0.1283
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0128 0.0506 0.0966
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0075 0.0205 0.1262
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0047 0.0046 0.0281
Echinococcus granulosus cathepsin L 0.0099 0.0338 0.0655
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0096 0.0325 0.1995
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0803 0.4345 1
Schistosoma mansoni peptidase 0.0043 0.002 0.0039
Trypanosoma brucei cysteine peptidase, putative 0.0554 0.2926 0.6661
Echinococcus multilocularis calpain family protein 1, d 0.0213 0.0988 0.1916
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0388 0.1984 0.4443
Trypanosoma brucei Calpain-like protein 1.1 0.0803 0.4345 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Echinococcus multilocularis cathepsin L 0.0099 0.0338 0.0655
Trichomonas vaginalis conserved hypothetical protein 0.0213 0.0988 0.6069
Entamoeba histolytica peptidase, C54 family 0.0045 0.0032 0.0236
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0186 0.0833 0.5116
Toxoplasma gondii cathepsin CPL 0.0186 0.0833 0.0833
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0069 0.017 0.0391
Trypanosoma cruzi SUMO1/Ulp2, putative 0.0175 0.0774 0.1782
Brugia malayi Cathepsin L-like precursor 0.0186 0.0833 0.1615
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0335 0.1684 0.3738
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0043 0.002 0.0039
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0397 0.2032 0.4557
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0076 0.0209 0.0405
Schistosoma mansoni 3-dehydroquinate synthase 0.0112 0.0415 0.0805
Entamoeba histolytica cysteine protease, putative 0.0099 0.0338 0.2467
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0453 0.2351 0.5307
Leishmania major trypanothione synthetase-like protein 0.0066 0.015 0.0128
Plasmodium falciparum chorismate synthase 0.1798 1 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0063 0.0134 0.0309
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0554 0.2926 0.6735
Trypanosoma brucei SUMO1/Ulp2, putative 0.0175 0.0774 0.1596
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0213 0.0988 0.6069
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0205 0.0946 0.2176
Brugia malayi Cathepsin L-like precursor 0.0186 0.0833 0.1615
Loa Loa (eye worm) hypothetical protein 0.008 0.0232 0.045
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0059 0.0115 0.0265
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0122 0.0468 0.0908
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). 0.0887 0.4818 1
Leishmania major calpain protease-like protein 0.0244 0.1164 0.2513
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0269 0.1307 0.2535
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0255 0.1225 0.2658
Onchocerca volvulus Cathepsin L homolog 0.0186 0.0833 1
Plasmodium falciparum ubiquitin specific protease, putative 0.0043 0.002 0.002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.002 0.0124
Loa Loa (eye worm) hypothetical protein 0.0059 0.0115 0.0223
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0059 0.0115 0.0708
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0122 0.0468 0.0876

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1533 nM Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cells ChEMBL. 8393115
IC50 (binding) = 1533 nM Binding affinity towards cloned neurokinin 1 receptor, based on the displacement of [125I]-labeled substance P ChEMBL. 7513763
IC50 (binding) = 1533 nM Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cells ChEMBL. 8393115
IC50 (binding) = 1533 nM Binding affinity towards cloned neurokinin 1 receptor, based on the displacement of [125I]-labeled substance P ChEMBL. 7513763
IC50 (binding) > 5 uM Binding affinity to the NK2 receptor assayed by displacement of [125I]-Neurokinin A ChEMBL. 7513763
IC50 (binding) > 5 uM Affinity to NK3 receptors assayed by displacement of [125I]-Bolton-Hunter labeled eledoisin radioligand ChEMBL. 7513763
IC50 (binding) > 5 uM Binding affinity to the NK2 receptor assayed by displacement of [125I]-Neurokinin A ChEMBL. 7513763
IC50 (binding) > 5 uM Affinity to NK3 receptors assayed by displacement of [125I]-Bolton-Hunter labeled eledoisin radioligand ChEMBL. 7513763

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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