Detailed information for compound 305946

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 545.609 | Formula: C28H27N5O5S
  • H donors: 1 H acceptors: 6 LogP: 4.21 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: C#CCOc1nc(nc(c1Oc1ccccc1OC)NS(=O)(=O)c1ccc(cc1)C(C)(C)C)c1cnccn1
  • InChi: 1S/C28H27N5O5S/c1-6-17-37-27-24(38-23-10-8-7-9-22(23)36-5)26(31-25(32-27)21-18-29-15-16-30-21)33-39(34,35)20-13-11-19(12-14-20)28(2,3)4/h1,7-16,18H,17H2,2-5H3,(H,31,32,33)
  • InChiKey: WLIQAZXJDQKSEC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens endothelin receptor type B Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni nAChR subunit 0.0136 0.0292 0.067
Schistosoma mansoni serine/threonine protein kinase 0.0543 0.2495 0.5915
Schistosoma mansoni protein kinase C mu 0.0364 0.1525 0.3607
Echinococcus multilocularis Immunoglobulin 0.0136 0.0291 0.0285
Entamoeba histolytica protein kinase, putative 0.0238 0.0841 0.2072
Schistosoma mansoni protein kinase 0.0179 0.0521 0.1214
Loa Loa (eye worm) hypothetical protein 0.0155 0.0393 0.0393
Trichomonas vaginalis CAMK family protein kinase 0.0139 0.0306 0.0632
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0136 0.0292 0.0286
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0088 0.0007
Echinococcus multilocularis dual specificity 0.0164 0.0441 0.0453
Echinococcus granulosus mitogen activated protein kinase 3 0.0158 0.041 0.0488
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0511 0.119
Trichomonas vaginalis CMGC family protein kinase 0.0251 0.0912 0.2369
Loa Loa (eye worm) hypothetical protein 0.0246 0.0883 0.0883
Trypanosoma brucei aurora B kinase 0.0286 0.11 0.2824
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0238 0.0841 0.2072
Schistosoma mansoni nAChR subunit 0.0136 0.0292 0.067
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0102 0.0108 0.0093
Giardia lamblia Kinase, STE STE20 0.0163 0.0436 0.1309
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0158 0.041 0.1349
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.091 0.2141
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0238 0.0841 0.3135
Brugia malayi map kinase activated protein kinase protein 2 0.0799 0.3879 0.3879
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0088 0.0007
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.055 0.253 0.5412
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.015 0.0363 0.0366
Echinococcus granulosus titin 0.0109 0.0143 0.0139
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0251 0.0912 0.0912
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0132 0.0266 0.0299
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0413 0.1788 0.1963
Loa Loa (eye worm) hypothetical protein 0.0117 0.0189 0.0189
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0286 0.0575
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0099 0.0088 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0286 0.0575
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.015 0.0363 0.0839
Entamoeba histolytica protein kinase domain containing protein 0.0119 0.0199 0.0212
Echinococcus multilocularis serine:threonine protein kinase 3 0.0516 0.2345 0.2588
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0143 0.0326 0.0326
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0136 0.0292 0.0292
Plasmodium vivax unspecified product 0.0192 0.0593 0.3235
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0124 0.0226 0.0248
Loa Loa (eye worm) hypothetical protein 0.0387 0.1649 0.1649
Brugia malayi Sex muscle abnormal protein 5 0.0117 0.0189 0.0189
Echinococcus multilocularis tyrosine protein kinase HCK 0.0187 0.0568 0.0595
Onchocerca volvulus 0.0136 0.0292 0.0395
Brugia malayi Protein kinase domain containing protein 0.0381 0.1618 0.1618
Echinococcus granulosus c-Jun N-terminal kinases 0.0531 0.2428 0.3123
Trichomonas vaginalis CMGC family protein kinase 0.0251 0.0912 0.2369
Trichomonas vaginalis AGC family protein kinase 0.0381 0.1618 0.4389
Loa Loa (eye worm) TK/EPH protein kinase 0.0234 0.0821 0.0821
Echinococcus granulosus tyrosine protein kinase Srms 0.0561 0.2593 0.3339
Plasmodium falciparum protein kinase 5 0.0231 0.0802 0.4112
Schistosoma mansoni serine/threonine protein kinase 0.0657 0.3108 0.7375
Schistosoma mansoni tyrosine kinase 0.0475 0.2125 0.5034
Trichomonas vaginalis AGC family protein kinase 0.0286 0.11 0.2907
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0238 0.0841 0.3018
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0534 0.2444 0.3145
Giardia lamblia Kinase, CAMK CAMKL 0.0135 0.0286 0.0677
Onchocerca volvulus 0.0286 0.1104 0.2216
Schistosoma mansoni cell adhesion molecule 0.0189 0.0576 0.1347
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0286 0.0575
Echinococcus granulosus tyrosine protein kinase HCK 0.0187 0.0568 0.0693
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0316 0.1263 0.1263
Echinococcus multilocularis raf serine:threonine protein kinase 0.0144 0.0335 0.0334
Brugia malayi excitatory GABA receptor EXP-1A 0.0136 0.0292 0.0292
Brugia malayi Protein kinase domain containing protein 0.0238 0.0841 0.0841
Echinococcus multilocularis casein kinase I alpha 0.0171 0.0479 0.0496
Brugia malayi Homeodomain interacting protein kinase protein 1 0.023 0.08 0.08
Trichomonas vaginalis CAMK family protein kinase 0.0543 0.2495 0.6901
Schistosoma mansoni titin 0.0109 0.0143 0.0315
Echinococcus multilocularis epidermal growth factor receptor 0.0575 0.2666 0.2948
Brugia malayi Immunoglobulin I-set domain containing protein 0.0155 0.0393 0.0393
Echinococcus granulosus glycine receptor subunit alpha 1 0.0136 0.0292 0.0334
Brugia malayi p70 ribosomal S6 kinase beta 0.0719 0.3447 0.3447
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0139 0.0306 0.0302
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0334 0.1363 0.1487
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0135 0.0286 0.0834
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.0756 0.1774
Echinococcus granulosus casein kinase I delta 0.0171 0.0479 0.0578
Brugia malayi Protein kinase c protein 2 0.0216 0.0725 0.0725
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0385 0.0891
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0479 0.1115
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0644 0.304 0.304
Echinococcus multilocularis casein kinase I delta 0.0171 0.0479 0.0496
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0136 0.0292 0.0292
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0147 0.0351 0.0352
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0136 0.0292 0.0292
Entamoeba histolytica protein kinase, putative 0.0132 0.0266 0.0407
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0136 0.0292 0.0292
Onchocerca volvulus 0.0136 0.0292 0.0395
Schistosoma mansoni protein kinase 0.044 0.1936 0.4585
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0136 0.0292 0.0292
Echinococcus granulosus tyrosine protein kinase ABL1 0.0353 0.1463 0.1864
Schistosoma mansoni serine/threonine protein kinase 0.0238 0.0841 0.1976
Brugia malayi Fes/CIP4 homology domain containing protein 0.0125 0.0232 0.0232
Echinococcus granulosus calcium activated potassium channel 0.0222 0.0756 0.0939
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0124 0.0226 0.0213
Trichomonas vaginalis AGC family protein kinase 0.0743 0.3577 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0158 0.041 0.1349
Schistosoma mansoni tyrosine kinase 0.0183 0.0545 0.1271
Schistosoma mansoni protein kinase 0.044 0.1936 0.4585
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0147 0.0351 0.0352
Echinococcus granulosus serine:threonine protein kinase 0.0221 0.075 0.0931
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0178 0.0516 0.2402
Brugia malayi Protein kinase domain containing protein 0.0662 0.3139 0.3139
Onchocerca volvulus 0.0311 0.1236 0.2511
Loa Loa (eye worm) TK protein kinase 0.0315 0.1261 0.1261
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0231 0.0802 0.1
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0147 0.0351 0.0351
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0192 0.0593 0.3235
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.023 0.08 0.0855
Schistosoma mansoni cell adhesion molecule 0.0089 0.0037 0.0062
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0286 0.11 0.2824
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0041 0.0072
Echinococcus multilocularis tyrosine protein kinase 0.0315 0.1261 0.1373
Loa Loa (eye worm) hypothetical protein 0.0481 0.2155 0.2155
Loa Loa (eye worm) hypothetical protein 0.0127 0.0243 0.0243
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0136 0.0292 0.0292
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0286 0.11 0.2824
Giardia lamblia Kinase, CAMK CAMKL 0.0135 0.0286 0.0677
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0231 0.0802 0.0802
Trichomonas vaginalis AGC family protein kinase 0.0743 0.3577 1
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0799 0.3879 0.502
Entamoeba histolytica protein kinase, putative 0.0147 0.0351 0.0653
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.036 0.15 0.1911
Schistosoma mansoni tyrosine kinase 0.0509 0.231 0.5476
Brugia malayi Protein kinase domain containing protein 0.0644 0.304 0.304
Echinococcus granulosus protein tyrosine kinase 0.0593 0.2763 0.3561
Trichomonas vaginalis CAMK family protein kinase 0.0543 0.2495 0.6901
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0413 0.1788 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0543 0.2495 1
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0109 0.0143 0.0143
Schistosoma mansoni serine/threonine protein kinase 0.036 0.1503 0.3552
Entamoeba histolytica protein kinase, putative 0.0132 0.0266 0.0407
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0305 0.1203 0.1308
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0681 0.3241 0.4186
Entamoeba histolytica protein kinase domain containing protein 0.0238 0.0841 0.2072
Echinococcus granulosus phosphorylase kinase gamma subunit 0.019 0.0582 0.0712
Echinococcus granulosus cyclin dependent kinase 0.0231 0.0802 0.1
Echinococcus granulosus epidermal growth factor receptor 0.086 0.421 0.5452
Schistosoma mansoni kinase 0.0581 0.2701 0.6406
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0593 0.1455
Schistosoma mansoni serine/threonine protein kinase 0.036 0.15 0.3546
Loa Loa (eye worm) ACC-1 protein 0.0136 0.0292 0.0292
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0136 0.0292 0.0334
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0136 0.0292 0.0286
Echinococcus multilocularis protein kinase c epsilon type 0.0441 0.1942 0.2136
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0593 0.1455
Brugia malayi Protein kinase domain containing protein 0.0486 0.2186 0.2186
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.016 0.0421 0.0855
Echinococcus multilocularis N chimaerin 0.015 0.0363 0.0366
Plasmodium vivax casein kinase 1, putative 0.0171 0.0479 0.2589
Echinococcus multilocularis casein kinase i 0.0171 0.0479 0.0496
Trichomonas vaginalis AGC family protein kinase 0.0286 0.11 0.2907
Schistosoma mansoni neuroglian 0.0089 0.0037 0.0062
Echinococcus granulosus epidermal growth factor receptor 0.0575 0.2666 0.3435
Loa Loa (eye worm) TK/ABL protein kinase 0.0353 0.1463 0.1463
Brugia malayi Protein kinase domain containing protein 0.0287 0.1109 0.1109
Brugia malayi protein unc-22 0.0109 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0169 0.0466 0.0466
Trypanosoma cruzi polo-like protein kinase, putative 0.0543 0.2495 1
Loa Loa (eye worm) RhoGAP domain-containing protein 0.015 0.0363 0.0363
Loa Loa (eye worm) casein kinase 0.0188 0.057 0.057
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0088 0.0007
Brugia malayi Temporarily assigned gene name protein 59 0.0127 0.0243 0.0243
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0231 0.0802 0.0802
Echinococcus multilocularis cyclin dependent kinase 0.0231 0.0802 0.0858
Echinococcus granulosus activin receptor type 0.0119 0.0199 0.0212
Loa Loa (eye worm) hypothetical protein 0.0126 0.0234 0.0234
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0534 0.2444 0.27
Onchocerca volvulus 0.0136 0.0292 0.0395
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0266 0.0996 0.2646
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0178 0.0516 0.1788
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0178 0.0516 0.1131
Loa Loa (eye worm) hypothetical protein 0.0147 0.0351 0.0351
Trypanosoma brucei polo-like protein kinase 0.0543 0.2495 0.6865
Schistosoma mansoni hypothetical protein 0.0169 0.0466 0.1084
Echinococcus multilocularis 0.0179 0.0521 0.0542
Echinococcus granulosus serine/threonine protein kinase 0.0437 0.1917 0.2456
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0127 0.0243 0.027
Brugia malayi serine/threonine kinase 12 0.0286 0.11 0.11
Echinococcus granulosus dual specificity 0.0164 0.0441 0.0527
Trypanosoma cruzi cdc2-related kinase 1 0.0231 0.0802 0.2975
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.04 0.1718 0.1885
Brugia malayi Protein kinase domain containing protein 0.036 0.1503 0.1503
Brugia malayi putative serine/threonine kinase SADA gamma 0.0135 0.0286 0.0286
Loa Loa (eye worm) TK/FAK protein kinase 0.0599 0.2797 0.2797
Echinococcus multilocularis dual specificity protein kinase clk2 0.0179 0.0523 0.0545
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0179 0.0523 0.1152
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0486 0.2186 0.2186
Echinococcus granulosus titin 0.0109 0.0143 0.0139
Leishmania major protein kinase, putative 0.0119 0.0199 0.0309
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0305 0.1203 0.1523
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0147 0.0351 0.0711
Echinococcus granulosus serine:threonine protein kinase N2 0.0135 0.0284 0.0323
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0102 0.0108 0.0079
Trypanosoma cruzi casein kinase, putative 0.0171 0.0479 0.1635
Brugia malayi Tyrosine-protein kinase abl-1 0.0133 0.0276 0.0276
Echinococcus granulosus serine threonine protein kinase nrc 0.0413 0.1788 0.2287
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0171 0.0479 0.0479
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0359 0.1498 0.1909
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.019 0.0582 0.0612
Trichomonas vaginalis AGC family protein kinase 0.0743 0.3577 1
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0334 0.1363 0.1733
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.041 0.0931
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.0859 0.202
Trichomonas vaginalis AGC family protein kinase 0.0381 0.1618 0.4389
Loa Loa (eye worm) SRC-1 0.0305 0.1203 0.1203
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0412 0.1785 0.1785
Echinococcus multilocularis PAK box P21 Rho binding 0.0118 0.0193 0.0176
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0286 0.0575
Schistosoma mansoni protein kinase 0.0119 0.0199 0.0447
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0286 0.0575
Brugia malayi Immunoglobulin I-set domain containing protein 0.0089 0.0037 0.0037
Echinococcus granulosus tyrosine protein kinase Src42A 0.0195 0.0608 0.0746
Schistosoma mansoni vam6/vps39 related 0.0127 0.0243 0.0553
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0284 0.1093 0.138
Schistosoma mansoni atypical protein kinase C 0.0622 0.2922 0.6933
Trypanosoma brucei casein kinase I, isoform 2 0.0171 0.0479 0.1025
Trichomonas vaginalis CAMK family protein kinase 0.0543 0.2495 0.6901
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0135 0.0286 0.028
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0146 0.0175
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0381 0.1618 0.1618
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0088 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.0163 0.0223
Schistosoma mansoni protein kinase 0.0306 0.121 0.2857
Schistosoma mansoni serine/threonine kinase 0.036 0.1503 0.3552
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0286 0.0575
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.041 0.0931
Schistosoma mansoni hypothetical protein 0.0127 0.0243 0.0553
Trichomonas vaginalis STE family protein kinase 0.0118 0.0193 0.031
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0359 0.1498 0.1639
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0534 0.2442 0.3143
Trichomonas vaginalis AGC family protein kinase 0.036 0.1503 0.4059
Trypanosoma brucei protein kinase, putative 0.0251 0.0912 0.228
Echinococcus multilocularis calcium dependent protein kinase 0.0094 0.0061 0.0028
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0147 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0135 0.0286 0.0286
Onchocerca volvulus 0.0137 0.0294 0.0398
Toxoplasma gondii aurora kinase 0.0286 0.11 0.2959
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0286 0.0575
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0726 0.3486 0.3486
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0412 0.1785 0.2283
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0136 0.0292 0.067
Loa Loa (eye worm) hypothetical protein 0.011 0.0146 0.0146
Echinococcus granulosus hypothetical protein 0.0126 0.0234 0.0257
Echinococcus granulosus twitchin 0.0226 0.0779 0.097
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0334 0.1363 0.1363
Trichomonas vaginalis CMGC family protein kinase 0.0164 0.0441 0.1018
Echinococcus granulosus Vam6:Vps39 protein 0.0127 0.0243 0.027
Loa Loa (eye worm) hypothetical protein 0.0184 0.0551 0.0551
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0286 0.0655
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.0163 0.0223
Entamoeba histolytica protein kinase , putative 0.0286 0.11 0.2824
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0364 0.1525 0.1525
Onchocerca volvulus 0.0603 0.2818 0.606
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0543 0.2495 1
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0136 0.0292 0.0286
Brugia malayi casein kinase I 0.0171 0.0479 0.0479
Schistosoma mansoni growth factor receptor-bound protein 0.0119 0.02 0.045
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Onchocerca volvulus 0.0232 0.0811 0.1557
Loa Loa (eye worm) hypothetical protein 0.0232 0.0811 0.0811
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0458 0.2035 0.2241
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0251 0.091 0.091
Loa Loa (eye worm) hypothetical protein 0.0207 0.0673 0.0673
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0106 0.0126 0.0126
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.0163 0.0223
Entamoeba histolytica casein kinase, putative 0.0192 0.0593 0.1355
Loa Loa (eye worm) CAMK/PIM protein kinase 0.055 0.253 0.253
Loa Loa (eye worm) AGC/PKA protein kinase 0.0178 0.0516 0.0516
Brugia malayi serine/threonine-protein kinase plk-2 0.0543 0.2495 0.2495
Echinococcus granulosus glycine receptor subunit beta 0.0136 0.0292 0.0334
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.025 0.0905 0.0905
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0136 0.0292 0.067
Schistosoma mansoni vesicular amine transporter 0.0136 0.0291 0.0668
Schistosoma mansoni protein kinase 0.0412 0.1785 0.4224
Echinococcus multilocularis growth factor receptor bound protein 2 0.0117 0.0189 0.017
Brugia malayi Protein kinase domain 0.0163 0.0436 0.0436
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0136 0.0292 0.0334
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0136 0.0292 0.0292
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0294 0.0294
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0136 0.0292 0.067
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0284 0.1093 0.1184
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0251 0.0912 0.3321
Toxoplasma gondii histone kinase SNF1, putative 0.0135 0.0286 0.0517
Echinococcus multilocularis dual specificity 0.0238 0.0841 0.0901
Echinococcus multilocularis tyrosine kinase 0.0137 0.0294 0.0288
Onchocerca volvulus 0.0137 0.0294 0.0398
Giardia lamblia Kinase, NEK 0.0266 0.0996 0.3674
Entamoeba histolytica protein kinase, putative 0.0142 0.0323 0.0572
Echinococcus granulosus serine:threonine protein kinase N2 0.0495 0.2233 0.287
Schistosoma mansoni serine/threonine protein kinase 0.0334 0.1363 0.3221
Giardia lamblia Kinase, PLK 0.0543 0.2495 1
Trichomonas vaginalis CMGC family protein kinase 0.0231 0.0802 0.2053
Echinococcus granulosus Protein kinase C brain isozyme 0.0523 0.2385 0.3068
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0516 0.1203
Echinococcus multilocularis insulin receptor 0.0662 0.3139 0.3479
Echinococcus granulosus fibroblast growth factor receptor 4 0.0475 0.2125 0.2728
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0154 0.0385 0.0455
Onchocerca volvulus 0.0109 0.0143 0.006
Echinococcus granulosus roundabout 2 0.0226 0.0775 0.0964
Schistosoma mansoni protein kinase 0.0494 0.2229 0.5282
Brugia malayi MAP kinase sur-1 0.0158 0.041 0.041
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0136 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0222 0.0753 0.0753
Entamoeba histolytica protein kinase, putative 0.0238 0.0841 0.2072
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0251 0.0912 0.1144
Echinococcus multilocularis ephrin type A receptor 4 A 0.0198 0.0625 0.0659
Echinococcus multilocularis mitogen activated protein kinase 14 0.0314 0.1253 0.1363
Loa Loa (eye worm) TK protein kinase 0.0382 0.162 0.162
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0231 0.0802 0.2065
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0286 0.0575
Brugia malayi protein kinase C II. 0.0441 0.1942 0.1942
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0179 0.0523 0.1152
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0132 0.0266 0.0257
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0136 0.0291 0.0668
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0437 0.1917 0.7603
Echinococcus multilocularis dual specificity 0.0164 0.0441 0.0453
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0135 0.0286 0.0286
Schistosoma mansoni growth factor receptor-bound protein 0.0117 0.0189 0.0424
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0088 0.0007
Brugia malayi intracellular kinase 0.0251 0.0912 0.0912
Entamoeba histolytica protein kinase domain containing protein 0.023 0.08 0.1953
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0314 0.1253 0.4845
Schistosoma mansoni serine/threonine protein kinase 0.0286 0.11 0.2594
Echinococcus multilocularis mitogen activated protein kinase 11 0.0314 0.1253 0.1363
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0441 0.1023
Onchocerca volvulus 0.0136 0.0292 0.0395
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0286 0.0575
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0136 0.0292 0.0334
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.041 0.0951
Entamoeba histolytica protein kinase, putative 0.0142 0.0323 0.0572
Brugia malayi SH2 domain containing protein 0.0137 0.0294 0.0294
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0441 0.1942 0.1942
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0136 0.0292 0.0334
Echinococcus granulosus c src tyrosine kinase 0.0183 0.0545 0.0663
Trypanosoma cruzi casein kinase, putative 0.0171 0.0479 0.1635
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0136 0.0291 0.0285
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0158 0.041 0.0825
Echinococcus multilocularis casein kinase ii subunit alpha 0.0192 0.0593 0.0624
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0593 0.1455
Entamoeba histolytica protein kinase, putative 0.0118 0.0193 0.0196
Giardia lamblia Kinase, CMGC CDK 0.0231 0.0802 0.2856
Echinococcus multilocularis Glutaredoxin protein 5 0.0359 0.1498 0.1639
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0413 0.1788 0.2287
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0258 0.0952 0.1196
Trichomonas vaginalis STE family protein kinase 0.0163 0.0436 0.1004
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0136 0.0292 0.0334
Schistosoma mansoni nAChR subunit 0.0136 0.0292 0.067
Onchocerca volvulus Putative nachr subunit 0.0136 0.0292 0.0395
Plasmodium vivax calcium-dependent protein kinase, putative 0.0147 0.0351 0.1862
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0221 0.075 0.075
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0181 0.0533 0.0556
Echinococcus multilocularis neuroglian 0.0173 0.049 0.0508
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0179 0.0523 0.0523
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.017 0.0475 0.0572
Loa Loa (eye worm) hypothetical protein 0.0387 0.1649 0.1649
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0178 0.0516 0.0537
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0127 0.0243 0.0553
Brugia malayi Protein kinase domain containing protein 0.0179 0.0523 0.0523
Trypanosoma brucei rac serine-threonine kinase, putative 0.0743 0.3577 1
Trichomonas vaginalis CMGC family protein kinase 0.0231 0.0802 0.2053
Echinococcus multilocularis serine:threonine protein kinase 0.0221 0.075 0.0799
Trypanosoma cruzi cdc2-related kinase 1 0.0231 0.0802 0.2975
Echinococcus granulosus Immunoglobulin 0.0136 0.0291 0.0333
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0147 0.0351 0.1862
Giardia lamblia Kinase, NEK 0.0266 0.0996 0.3674
Plasmodium falciparum calcium-dependent protein kinase 3 0.0147 0.0351 0.1416
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0543 0.2495 0.2756
Brugia malayi hypothetical protein 0.0251 0.091 0.091
Leishmania major protein kinase A catalytic subunit isoform 1 0.0178 0.0516 0.1648
Loa Loa (eye worm) hypothetical protein 0.0178 0.0516 0.0516
Echinococcus multilocularis aurora kinase A 0.0286 0.11 0.1193
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0516 0.1203
Echinococcus granulosus aurora kinase A 0.0286 0.11 0.1389
Leishmania major protein kinase, putative 0.016 0.0421 0.1245
Echinococcus granulosus defective proboscis extension response 0.0136 0.0291 0.0333
Schistosoma mansoni protein kinase 0.022 0.0744 0.1746
Leishmania major casein kinase II, putative 0.0192 0.0593 0.1974
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0178 0.0516 0.0537
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.041 0.0931
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0176 0.0507 0.0507
Schistosoma mansoni serine/threonine-protein kinase 0.0437 0.1917 0.454
Loa Loa (eye worm) hypothetical protein 0.0132 0.0269 0.0269
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0163 0.0436 0.0521
Entamoeba histolytica PH domain containing protein kinase, putative 0.0202 0.0645 0.1506
Toxoplasma gondii CMGC kinase, CK2 family 0.0192 0.0593 0.1438
Echinococcus granulosus protein kinase c epsilon type 0.0441 0.1942 0.2489
Trichomonas vaginalis CMGC family protein kinase 0.0164 0.0441 0.1018
Schistosoma mansoni tyrosine kinase 0.0509 0.231 0.5476
Onchocerca volvulus 0.0657 0.3108 0.6709
Trypanosoma brucei Casein kinase II 0.0192 0.0593 0.1355
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0181 0.0533 0.0648
Loa Loa (eye worm) hypothetical protein 0.0286 0.1104 0.1104
Trichomonas vaginalis CAMK family protein kinase 0.0543 0.2495 0.6901
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0147 0.0351 0.041
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.022 0.0744 0.0744
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.04 0.1718 0.2196
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0351 0.081
Leishmania major protein kinase, putative 0.0286 0.11 0.4114
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0119 0.0199 0.0471
Loa Loa (eye worm) hypothetical protein 0.0137 0.0294 0.0294
Entamoeba histolytica protein kinase, putative 0.0125 0.0228 0.0295
Trichomonas vaginalis CAMK family protein kinase 0.0246 0.0887 0.2296
Brugia malayi Stress-activated protein kinase jnk-1 0.0531 0.2428 0.2428
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1503 0.7691 1
Brugia malayi Cation transporter family protein 0.0136 0.0292 0.0292
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0136 0.0292 0.0292
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0147 0.0351 0.1862
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0137 0.0294 0.0488
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0136 0.0292 0.0292
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0231 0.0802 0.2856
Brugia malayi Fibronectin type III domain containing protein 0.0155 0.0393 0.0393
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0464 0.2068 0.2068
Echinococcus granulosus serine:threonine protein kinase MARK2 0.039 0.1663 0.2124
Echinococcus multilocularis CDC7 cell division cycle 7 0.0113 0.0163 0.0142
Echinococcus granulosus casein kinase I alpha 0.0171 0.0479 0.0578
Echinococcus granulosus tyrosine protein kinase shark 0.0359 0.1498 0.1908
Loa Loa (eye worm) CAMK protein kinase 0.0109 0.0143 0.0143
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0136 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0137 0.0294 0.0294
Trichomonas vaginalis CMGC family protein kinase 0.0164 0.0441 0.1018
Plasmodium falciparum protein kinase, putative 0.0119 0.0199 0.0508
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0231 0.0802 0.0802
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0171 0.0479 0.0479
Echinococcus multilocularis nervana 2 0.0359 0.1498 0.1639
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0136 0.0292 0.0292
Echinococcus multilocularis serine:threonine protein kinase 0.0221 0.075 0.0799
Onchocerca volvulus 0.0137 0.0294 0.0398
Trichomonas vaginalis AGC family protein kinase 0.0154 0.0385 0.0859
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0681 0.3241 0.3593
Onchocerca volvulus Serine\/threonine kinase homolog 0.019 0.0582 0.1045
Schistosoma mansoni serine/threonine protein kinase 0.0441 0.1942 0.4599
Schistosoma mansoni serine/threonine protein kinase 0.0179 0.0523 0.122
Brugia malayi STE20-like kinase MST 0.0516 0.2345 0.2345
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0286 0.0655
Entamoeba histolytica PH domain containing protein kinase, putative 0.0202 0.0645 0.1506
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0305 0.1203 0.1308
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0136 0.0292 0.0292
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0305 0.1203 0.1308
Schistosoma mansoni serine/threonine protein kinase 0.019 0.0582 0.1361
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0251 0.0912 0.2147
Echinococcus granulosus NCK adaptor protein 0.0117 0.0189 0.0198
Echinococcus granulosus protein kinase shaggy 0.0251 0.0912 0.1144
Entamoeba histolytica protein kinase 2, putative 0.0413 0.1788 0.4816
Echinococcus multilocularis nervana 2 0.0359 0.1498 0.1639
Echinococcus multilocularis 0.0126 0.0234 0.0221
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0136 0.0292 0.067
Echinococcus multilocularis myotubularin protein 13 0.0102 0.0108 0.008
Echinococcus multilocularis glycine receptor subunit beta 0.0136 0.0292 0.0286
Entamoeba histolytica PH domain containing protein kinase, putative 0.0437 0.1917 0.5191
Giardia lamblia Kinase, AGC AKT 0.0227 0.0783 0.2774
Echinococcus multilocularis nAChR subunit 0.0136 0.0292 0.0286
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0179 0.0523 0.1818
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0314 0.1253 0.4757
Brugia malayi casein kinase 1, delta 0.0171 0.0479 0.0479
Loa Loa (eye worm) CAMK/PIM protein kinase 0.055 0.253 0.253
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0258 0.0952 0.1026
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0305 0.1203 0.1308
Trichomonas vaginalis CMGC family protein kinase 0.0179 0.0523 0.1255
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0238 0.0841 0.0841
Loa Loa (eye worm) AGC/AKT protein kinase 0.0743 0.3577 0.3577
Echinococcus multilocularis casein kinase I alpha 0.0171 0.0479 0.0496
Giardia lamblia Kinase, CMGC CDK 0.0231 0.0802 0.2856
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0178 0.0516 0.1131
Giardia lamblia Kinase, CK1 Casein kinase 0.0171 0.0479 0.1493
Loa Loa (eye worm) TK/ROR protein kinase 0.0102 0.0108 0.0108
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0158 0.041 0.1349
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0579 0.2688 0.2688
Schistosoma mansoni protein kinase 0.0192 0.0593 0.1387
Echinococcus granulosus tyrosine protein kinase Lyn 0.0358 0.1492 0.1902
Brugia malayi Temporarily assigned gene name protein 59 0.0266 0.0995 0.0995
Schistosoma mansoni tyrosine kinase 0.0359 0.1498 0.3541
Echinococcus granulosus dual specificity 0.0238 0.0841 0.105
Schistosoma mansoni tyrosine kinase 0.086 0.421 1
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0164 0.0441 0.1475
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0286 0.0575
Echinococcus granulosus dual specificity testis-specific protein kinase 0.044 0.1936 0.2481
Trypanosoma cruzi casein kinase, putative 0.0171 0.0479 0.1635
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0286 0.11 0.1193
Loa Loa (eye worm) ACC-1 protein 0.0136 0.0292 0.0292
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0294 0.0294
Trichomonas vaginalis CMGC family protein kinase 0.0164 0.0441 0.1018
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0416 0.0965
Echinococcus multilocularis mitogen activated protein kinase 14 0.0314 0.1253 0.1363
Schistosoma mansoni serine/threonine protein kinase 0.0132 0.0266 0.0608
Schistosoma mansoni serine/threonine protein kinase 0.0495 0.2233 0.5293
Brugia malayi Egg laying defective protein 4 0.0159 0.0416 0.0416
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0494 0.2229 0.2864
Loa Loa (eye worm) hypothetical protein 0.0232 0.0811 0.0811
Entamoeba histolytica protein kinase, putative 0.036 0.1503 0.399
Entamoeba histolytica protein kinase, putative 0.0719 0.3447 0.9625
Schistosoma mansoni serine/threonine protein kinase 0.0799 0.3879 0.9213
Brugia malayi Protein kinase domain containing protein 0.022 0.0744 0.0744
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0136 0.0292 0.0292
Schistosoma mansoni tyrosine kinase 0.013 0.026 0.0593
Schistosoma mansoni serine/threonine protein kinase 0.0531 0.2428 0.5755
Trypanosoma cruzi Protein kinase B 0.0437 0.1917 0.7603
Trichomonas vaginalis CAMK family protein kinase 0.0543 0.2495 0.6901
Echinococcus multilocularis serine:threonine protein kinase 38 0.036 0.1503 0.1644
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0286 0.0575
Echinococcus granulosus mitogen activated protein kinase 14 0.0314 0.1253 0.1588
Schistosoma mansoni tyrosine kinase 0.0136 0.0291 0.0667
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0118 0.019 0.0434
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0159 0.0416 0.0425
Schistosoma mansoni serine/threonine protein kinase 0.0579 0.2688 0.6375
Plasmodium vivax tyrosine kinase-like protein, putative 0.0104 0.0114 0.0519
Onchocerca volvulus Serine\/threonine kinase homolog 0.0543 0.2495 0.5334
Brugia malayi Protein kinase domain containing protein 0.055 0.253 0.253
Echinococcus granulosus rho-associated protein kinase 1 0.0657 0.3108 0.4012
Trichomonas vaginalis STE family protein kinase 0.0163 0.0436 0.1004
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Leishmania major protein kinase A catalytic subunit 0.0178 0.0516 0.1648
Brugia malayi Protein kinase domain containing protein 0.0241 0.0859 0.0859
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0138 0.03 0.03
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0286 0.0575
Brugia malayi probable protein kinase 0.0306 0.121 0.121
Loa Loa (eye worm) TK protein kinase 0.0258 0.0952 0.0952
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0179 0.0523 0.1228
Echinococcus multilocularis mitogen activated protein kinase 11 0.0314 0.1253 0.1363
Brugia malayi Cam kinase protein 1 0.0147 0.0351 0.0351
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0575 0.2666 0.3435
Schistosoma mansoni tyrosine kinase 0.0288 0.1113 0.2625
Echinococcus multilocularis tyrosine protein kinase Abl 0.0266 0.0992 0.1071
Brugia malayi Variant SH3 domain containing protein 0.0098 0.0082 0.0082
Trichomonas vaginalis AGC family protein kinase 0.0743 0.3577 1
Trypanosoma brucei SNF1-related protein kinases, putative 0.0135 0.0286 0.0465
Brugia malayi Protein kinase domain containing protein 0.0137 0.0294 0.0294
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.036 0.15 0.164
Plasmodium falciparum serine/threonine protein kinase KIN 0.0135 0.0286 0.1029
Loa Loa (eye worm) hypothetical protein 0.0089 0.0037 0.0037
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0458 0.2035 0.2611
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0164 0.0441 0.0441
Trichomonas vaginalis STE family protein kinase 0.016 0.0421 0.096
Leishmania major casein kinase, putative 0.0171 0.0479 0.1493
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0593 0.1455
Loa Loa (eye worm) protein kinase domain-containing protein 0.0241 0.0859 0.0859
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0334 0.1363 0.1363
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0314 0.1253 0.4845
Echinococcus multilocularis mitogen activated protein kinase 3 0.0158 0.041 0.0419
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0475 0.2125 0.2728
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.193 1 1
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.036 0.1503 0.1644
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Echinococcus multilocularis glycine receptor subunit beta 0.0136 0.0292 0.0286
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0178 0.0516 0.0537
Schistosoma mansoni serine/threonine protein kinase 0.0285 0.1095 0.2581
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0164 0.0441 0.0913
Echinococcus granulosus nAChR subunit 0.0136 0.0292 0.0334
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.016 0.0421 0.0855
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0136 0.0292 0.0292
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0117 0.0189 0.0189
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0088 0.0007
Echinococcus granulosus protein kinase C gamma type 0.0444 0.196 0.2512
Onchocerca volvulus 0.0136 0.0292 0.0395
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0251 0.0912 0.332
Entamoeba histolytica cell division protein kinase 2, putative 0.0231 0.0802 0.196
Brugia malayi P38 map kinase family protein 2 0.0314 0.1253 0.1253
Echinococcus multilocularis tyrosine protein kinase Srms 0.0258 0.0952 0.1026
Echinococcus multilocularis serine threonine protein kinase 0.0444 0.196 0.2156
Brugia malayi Immunoglobulin I-set domain containing protein 0.0089 0.0037 0.0037
Trichomonas vaginalis AGC family protein kinase 0.0743 0.3577 1
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0125 0.0228 0.0295
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0644 0.304 0.304
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0178 0.0516 0.0626
Brugia malayi Variant SH3 domain containing protein 0.0117 0.0189 0.0189
Loa Loa (eye worm) thyroid receptor interactor 0.0125 0.0232 0.0232
Trichomonas vaginalis STE family protein kinase 0.0266 0.0996 0.2608
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0286 0.0655
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0132 0.0266 0.03
Schistosoma mansoni serine/threonine protein kinase 0.0516 0.2346 0.5562
Echinococcus granulosus N chimaerin 0.015 0.0363 0.0427
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0294 0.0294
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0179 0.0521 0.0521
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0195 0.0608 0.064
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.0802 0.1884
Trypanosoma cruzi cdc2-related kinase 3 0.0231 0.0802 0.2975
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0154 0.0385 0.039
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0164 0.0441 0.098
Entamoeba histolytica protein kinase, putative 0.015 0.0365 0.0694
Entamoeba histolytica hypothetical protein 0.0396 0.1696 0.4551
Loa Loa (eye worm) hypothetical protein 0.0207 0.0673 0.0673
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0127 0.0243 0.0231
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0305 0.1203 0.1523
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0163 0.0363
Trichomonas vaginalis CK1 family protein kinase 0.0171 0.0479 0.1128
Plasmodium vivax serine/threonine kinase-1, putative 0.0179 0.0523 0.2839
Trypanosoma cruzi aurora B kinase, putative 0.0286 0.11 0.4213
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0136 0.0292 0.0292
Echinococcus granulosus serine:threonine protein kinase 0.0221 0.075 0.0931
Schistosoma mansoni tyrosine kinase 0.0305 0.1203 0.2839
Brugia malayi Variant SH3 domain containing protein 0.0117 0.0189 0.0189
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0139 0.0306 0.0352
Brugia malayi serine/threonine protein kinase 6 0.0286 0.11 0.11
Schistosoma mansoni protein kinase 0.0163 0.0436 0.1012
Echinococcus granulosus dual specificity 0.0164 0.0441 0.0527
Plasmodium falciparum glycogen synthase kinase 3 0.0251 0.0912 0.4771
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.015 0.0363 0.0427
Brugia malayi Immunoglobulin I-set domain containing protein 0.1061 0.5298 0.5298
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0164 0.0441 0.133
Echinococcus multilocularis casein kinase I alpha 0.0171 0.0479 0.0496
Echinococcus granulosus CDC7 cell division cycle 7 0.0113 0.0163 0.0165
Plasmodium falciparum calcium-dependent protein kinase 5 0.0147 0.0351 0.1416
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0136 0.0292 0.067
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0251 0.0912 0.0912
Echinococcus multilocularis expressed protein 0.0106 0.0126 0.01
Entamoeba histolytica protein kinase, putative 0.0187 0.0568 0.128
Entamoeba histolytica protein kinase, putative 0.0286 0.11 0.2824
Brugia malayi Variant SH3 domain containing protein 0.015 0.0363 0.0363
Brugia malayi Protein kinase domain containing protein 0.0599 0.2797 0.2797
Echinococcus granulosus glycine receptor subunit beta 0.0136 0.0292 0.0334
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0136 0.0292 0.0286
Brugia malayi protein kinase C3,putative 0.0303 0.1195 0.1195
Plasmodium vivax protein kinase Crk2 0.0231 0.0802 0.4418
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0127 0.0243 0.0341
Schistosoma mansoni nephrin 0.0089 0.0037 0.0062
Loa Loa (eye worm) hypothetical protein 0.016 0.0422 0.0422
Echinococcus multilocularis NCK adaptor protein 0.0119 0.02 0.0183
Echinococcus granulosus casein kinase ii subunit alpha 0.0192 0.0593 0.0727
Entamoeba histolytica protein kinase domain containing protein 0.0251 0.0912 0.228
Giardia lamblia Kinase, NEK 0.0266 0.0996 0.3674
Echinococcus multilocularis activin receptor type 0.0119 0.0199 0.0182
Brugia malayi Serine/threonine-protein kinase SULU 0.0251 0.091 0.091
Loa Loa (eye worm) hypothetical protein 0.0127 0.0243 0.0243
Echinococcus multilocularis myosin iiia 0.016 0.0421 0.043
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.039 0.1663 0.1823
Loa Loa (eye worm) AGC/NDR protein kinase 0.036 0.1503 0.1503
Brugia malayi Immunoglobulin I-set domain containing protein 0.0512 0.2323 0.2323
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0088 0.0007
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Echinococcus granulosus cGMP dependent protein kinase 0.0159 0.0416 0.0495
Echinococcus multilocularis 0.0244 0.0874 0.0938
Schistosoma mansoni protein kinase 0.0494 0.2229 0.5282
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0136 0.0292 0.0334
Loa Loa (eye worm) hypothetical protein 0.0365 0.1529 0.1529
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0085 0.0177
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0127 0.0243 0.0656
Onchocerca volvulus 0.0137 0.0294 0.0398
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0251 0.0912 0.0982
Schistosoma mansoni nck2/grb4 0.0117 0.0189 0.0424
Toxoplasma gondii AGC kinase 0.0719 0.3447 1
Echinococcus granulosus dual specificity 0.0164 0.0441 0.0527
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Loa Loa (eye worm) LGC-31 protein 0.0136 0.0292 0.0292
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0135 0.0286 0.0465
Brugia malayi C1-like domain containing protein 0.0364 0.1525 0.1525
Brugia malayi Hr1 repeat family protein 0.0495 0.2233 0.2233
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Entamoeba histolytica PH domain containing protein kinase, putative 0.0437 0.1917 0.5191
Loa Loa (eye worm) hypothetical protein 0.0102 0.0108 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.0802 0.1884
Leishmania major protein kinase, putative 0.0147 0.0351 0.0951
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0286 0.11 0.1389
Trichomonas vaginalis CK1 family protein kinase 0.0171 0.0479 0.1128
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0136 0.0292 0.0286
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0335 0.0771
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0136 0.0292 0.0292
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0543 0.2495 0.3211
Entamoeba histolytica serine/threonine protein kinase, putative 0.0543 0.2495 0.6865
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0163 0.0436 0.0521
Echinococcus multilocularis hypothetical protein 0.0169 0.0466 0.0482
Entamoeba histolytica protein kinase domain containing protein 0.0286 0.11 0.2824
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0136 0.0292 0.0292
Giardia lamblia Aurora kinase 0.0286 0.11 0.4114
Echinococcus multilocularis protein tyrosine kinase 0.0593 0.2763 0.3057
Trichomonas vaginalis AGC family protein kinase 0.0405 0.1747 0.476
Echinococcus granulosus serine:threonine protein kinase 3 0.0516 0.2345 0.3015
Schistosoma mansoni ste20-related kinase 0.0409 0.1767 0.4182
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0308 0.1219 0.1219
Giardia lamblia Kinase, CMGC DYRK 0.0164 0.0441 0.133
Schistosoma mansoni tyrosine kinase 0.0662 0.3139 0.745
Echinococcus multilocularis cyclin dependent kinase 1 0.0231 0.0802 0.0858
Entamoeba histolytica protein kinase, putative 0.0743 0.3577 1
Trypanosoma brucei cdc2-related kinase 3 0.0231 0.0802 0.196
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1061 0.5298 0.5298
Leishmania major protein kinase, putative 0.0179 0.0523 0.1679
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0178 0.0516 0.1788
Loa Loa (eye worm) hypothetical protein 0.0095 0.0068 0.0068
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0136 0.0292 0.0292
Echinococcus multilocularis expressed conserved protein 0.0159 0.0416 0.0425
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.016 0.0421 0.0855
Trichomonas vaginalis STE family protein kinase 0.0163 0.0436 0.1004
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0364 0.1525 0.1525
Echinococcus multilocularis twitchin 0.009 0.0041 0.0005
Echinococcus granulosus glycine receptor subunit alpha 1 0.0136 0.0292 0.0334
Echinococcus granulosus cyclin dependent kinase 1 0.0231 0.0802 0.1
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0314 0.1253 0.1253
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0085 0.0177
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0534 0.2442 0.2697
Brugia malayi Casein kinase II, alpha chain 0.0192 0.0593 0.0593
Echinococcus multilocularis serine:threonine protein kinase N2 0.0495 0.2233 0.2463
Giardia lamblia Kinase, CMGC GSK 0.0251 0.0912 0.3321
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0799 0.3879 0.3879
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0147 0.0351 0.0653
Onchocerca volvulus 0.0113 0.0163 0.0105
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0136 0.0292 0.067
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0147 0.0351 0.0351
Brugia malayi Protein kinase domain containing protein 0.019 0.0582 0.0582
Echinococcus granulosus mitogen activated protein kinase 0.0158 0.041 0.0488
Schistosoma mansoni nAChR subunit 0.0136 0.0292 0.067
Trichomonas vaginalis CAMK family protein kinase 0.0246 0.0887 0.2296
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0106 0.0126 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.023 0.08 0.1878
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0159 0.0416 0.0425
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0136 0.0292 0.0292
Schistosoma mansoni serine/threonine protein kinase 0.055 0.253 0.5998
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.036 0.1503 0.1644
Schistosoma mansoni protein kinase 0.0118 0.0193 0.0435
Entamoeba histolytica protein kinase, putative 0.0163 0.0436 0.0899
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0147 0.0351 0.0711
Onchocerca volvulus 0.0825 0.4021 0.8757
Trichomonas vaginalis CAMK family protein kinase 0.0543 0.2495 0.6901
Schistosoma mansoni serine/threonine protein kinase 0.036 0.1503 0.3552
Brugia malayi Protein kinase domain containing protein 0.0644 0.304 0.304
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0099 0.0088 0.0007
Brugia malayi hypothetical protein 0.0137 0.0294 0.0294
Echinococcus multilocularis protein kinase c iota type 0.061 0.2854 0.3159
Loa Loa (eye worm) hypothetical protein 0.0286 0.1104 0.1104
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0178 0.0516 0.2797
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.0756 0.1774
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Entamoeba histolytica protein kinase domain containing protein 0.0164 0.0441 0.0913
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0286 0.0575
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0543 0.2495 0.2495
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.036 0.1503 0.1915
Brugia malayi Serine/threonine-protein kinase Pim-3 0.055 0.253 0.253
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0179 0.0523 0.1818
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0158 0.041 0.041
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0475 0.2125 0.2341
Loa Loa (eye worm) hypothetical protein 0.0155 0.0393 0.0393
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0147 0.0351 0.1862
Echinococcus granulosus nervana 2 0.0359 0.1498 0.1909
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0135 0.0286 0.0677
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0799 0.3879 0.4309
Schistosoma mansoni nAChR subunit 0.0136 0.0292 0.067
Schistosoma mansoni nAChR subunit 0.0136 0.0292 0.067
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0347 0.1431 0.1431
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0251 0.091 0.1141
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0183 0.0545 0.1271
Schistosoma mansoni nephrin 0.0192 0.0591 0.1383
Loa Loa (eye worm) TK/EGFR protein kinase 0.086 0.421 0.421
Schistosoma mansoni serine/threonine protein kinase 0.0534 0.2442 0.5791
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0098 0.0085 0.0085
Schistosoma mansoni protein kinase 0.0286 0.11 0.2594
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0136 0.0292 0.0334
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0453 0.2004 0.2206
Schistosoma mansoni tyrosine kinase 0.0593 0.2763 0.6554
Brugia malayi Protein kinase domain containing protein 0.0154 0.0385 0.0385
Loa Loa (eye worm) TK protein kinase 0.0187 0.0568 0.0568
Loa Loa (eye worm) CAMK/PHK protein kinase 0.019 0.0582 0.0582
Entamoeba histolytica protein kinase, putative 0.0154 0.0385 0.0752
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0088 0.0007
Toxoplasma gondii casein kinase I 0.0171 0.0479 0.1096
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0523 0.2385 0.2633
Loa Loa (eye worm) TK/INSR protein kinase 0.0662 0.3139 0.3139
Schistosoma mansoni adapter molecule crk 0.0117 0.0189 0.0424
Entamoeba histolytica p21-activated kinase 0.0187 0.0565 0.1274
Giardia lamblia Kinase, CMGC CK2 0.0192 0.0593 0.1974
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0516 0.1203
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.016 0.0421 0.1392
Echinococcus granulosus protein kinase c iota type 0.061 0.2854 0.3681
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0593 0.1455
Schistosoma mansoni tyrosine kinase 0.0575 0.2666 0.6324
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.0756 0.1774
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0294 0.0294
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0253 0.0921 0.1155
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0158 0.041 0.1202
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0286 0.0575
Echinococcus multilocularis rac serine:threonine kinase 0.0437 0.1917 0.2108
Brugia malayi Doublecortin family protein 0.0176 0.0507 0.0507
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0119 0.0199 0.0471
Echinococcus multilocularis roundabout 2 0.0226 0.0775 0.0828
Echinococcus granulosus insulin receptor 0.0662 0.3139 0.4053
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0179 0.0523 0.1818
Onchocerca volvulus 0.0132 0.0269 0.0342
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0154 0.0385 0.0385
Brugia malayi hypothetical protein 0.0127 0.0243 0.0243
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.016 0.0421 0.1392
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0135 0.0286 0.1495
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.055 0.253 0.3257
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0416 0.0965
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.055 0.253 0.2795
Echinococcus multilocularis tyrosine protein kinase Blk 0.0258 0.0952 0.1026
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0347 0.1431 0.1431
Loa Loa (eye worm) TK protein kinase 0.0512 0.2323 0.2323
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0305 0.1203 0.1308
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0178 0.0516 0.0516
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0231 0.0802 0.2856
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0088 0.0007
Brugia malayi Pleckstrin Homology Domain 0.0102 0.0108 0.0108
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0136 0.0292 0.0286
Schistosoma mansoni tyrosine kinase 0.0183 0.0545 0.1271
Leishmania major protein kinase, putative 0.0179 0.0523 0.1679
Brugia malayi Protein kinase domain containing protein 0.0231 0.0802 0.0802
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0088 0.0007
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Echinococcus multilocularis protein kinase shaggy 0.0251 0.0912 0.0982
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.039 0.1663 0.1823
Brugia malayi SH2 domain containing protein 0.0453 0.2004 0.2004
Echinococcus granulosus calcium dependent protein kinase 0.0094 0.0061 0.0032
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0098 0.0082 0.0082
Echinococcus multilocularis calcium activated potassium channel 0.0222 0.0756 0.0806
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0178 0.0516 0.1788
Echinococcus granulosus tyrosine protein kinase Src64B 0.0305 0.1203 0.1523
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0119 0.0199 0.0255
Schistosoma mansoni protein kinase 0.0494 0.2229 0.5282
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0154 0.0385 0.0385
Schistosoma mansoni serine/threonine-protein kinase 0.0437 0.1917 0.454
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0147 0.0351 0.041
Schistosoma mansoni tyrosine kinase 0.0305 0.1203 0.2839
Brugia malayi Protein kinase domain containing protein 0.0137 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Echinococcus multilocularis cyclin dependent kinase 1 0.0231 0.0802 0.0858
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0089 0.0037 0.0037
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.0177 0.0513 0.0513
Echinococcus granulosus casein kinase I alpha 0.0171 0.0479 0.0578
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0171 0.0479 0.0479
Brugia malayi Protein kinase domain containing protein 0.0221 0.075 0.075
Onchocerca volvulus 0.0118 0.019 0.0165
Schistosoma mansoni serine/threonine protein kinase 0.0179 0.0523 0.122
Loa Loa (eye worm) hypothetical protein 0.0253 0.0921 0.0921
Trichomonas vaginalis AGC family protein kinase 0.0178 0.0516 0.1234
Schistosoma mansoni tyrosine kinase 0.0575 0.2666 0.6324
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0178 0.0516 0.1206
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0163 0.0436 0.0447
Giardia lamblia Kinase, CMGC MAPK 0.0158 0.041 0.1202
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0251 0.091 0.0979
Echinococcus multilocularis c src tyrosine kinase 0.0183 0.0545 0.0569
Entamoeba histolytica protein kinase, putative 0.0251 0.0912 0.228
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0475 0.2125 0.2341
Trichomonas vaginalis AGC family protein kinase 0.0743 0.3577 1
Trichomonas vaginalis AGC family protein kinase 0.0286 0.11 0.2907
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0286 0.0655
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.036 0.1503 0.1915
Brugia malayi Protein kinase domain containing protein 0.0308 0.1219 0.1219
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0088 0.0007
Echinococcus multilocularis epidermal growth factor receptor 0.086 0.421 0.468
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0136 0.0292 0.0286
Loa Loa (eye worm) hypothetical protein 0.0155 0.0393 0.0393
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0136 0.0291 0.0668
Entamoeba histolytica casein kinase, putative 0.0171 0.0479 0.1025
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0158 0.041 0.1202
Echinococcus granulosus Glutaredoxin protein 5 0.0359 0.1498 0.1909
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0227 0.0783 0.0783
Entamoeba histolytica protein kinase, putative 0.0286 0.11 0.2824
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0412 0.1785 0.196
Loa Loa (eye worm) hypothetical protein 0.0136 0.0291 0.0291
Loa Loa (eye worm) hypothetical protein 0.0184 0.0551 0.0551
Brugia malayi RhoGAP domain containing protein 0.015 0.0363 0.0363
Plasmodium falciparum serine/threonine protein kinase, putative 0.0286 0.11 0.5894
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0413 0.1788 0.7065
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0088 0.0007
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0089 0.0037 0.0062
Trichomonas vaginalis CMGC family protein kinase 0.0158 0.041 0.0931
Brugia malayi Protein kinase domain containing protein 0.0378 0.1597 0.1597
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0147 0.0351 0.0352
Entamoeba histolytica hypothetical protein 0.0238 0.0841 0.2072
Echinococcus granulosus myotubularin protein 13 0.0102 0.0108 0.0093
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0328 0.1328 0.356
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.015 0.0363 0.0839
Schistosoma mansoni cell adhesion molecule 0.0089 0.0037 0.0062
Trichomonas vaginalis STE family protein kinase 0.0163 0.0436 0.1004
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0305 0.1203 0.1308
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0238 0.0841 0.3135
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0127 0.0243 0.0553
Loa Loa (eye worm) hypothetical protein 0.0646 0.3053 0.3053
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0119 0.0199 0.0212
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0147 0.0351 0.041
Brugia malayi SRC-1 0.0305 0.1203 0.1203
Echinococcus granulosus tyrosine protein kinase 0.0315 0.1261 0.1599
Loa Loa (eye worm) hypothetical protein 0.0221 0.075 0.075
Echinococcus granulosus cGMP dependent protein kinase 1 0.0159 0.0416 0.0495
Echinococcus granulosus glycine receptor subunit alpha 1 0.0136 0.0292 0.0334
Brugia malayi Kinase associated domain 1 family protein 0.0169 0.0466 0.0466
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0286 0.0575
Schistosoma mansoni serine/threonine protein kinase 0.0523 0.2385 0.5654
Trichomonas vaginalis CAMK family protein kinase 0.0139 0.0306 0.0632
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0143 0.0315
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0178 0.0516 0.1131
Loa Loa (eye worm) AUR protein kinase 0.0286 0.11 0.11
Echinococcus multilocularis casein kinase I delta 0.0171 0.0479 0.0496
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0088 0.0007
Brugia malayi cell division control protein 2 homolog 0.0231 0.0802 0.0802
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0088 0.0007
Leishmania major protein kinase A catalytic subunit isoform 2 0.0178 0.0516 0.1648
Brugia malayi Tyrosine-protein kinase abl-1 0.0266 0.0992 0.0992
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Trypanosoma brucei cdc2-related kinase 1 0.0231 0.0802 0.196
Trichomonas vaginalis AGC family protein kinase 0.0266 0.0996 0.2608
Onchocerca volvulus 0.0113 0.0163 0.0105
Brugia malayi hypothetical protein 0.0155 0.0393 0.0393
Schistosoma mansoni vav2 0.0174 0.0493 0.1148
Echinococcus granulosus raf serine:threonine protein kinase 0.0144 0.0335 0.0389
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0719 0.3447 0.3447
Echinococcus granulosus casein kinase I delta 0.0171 0.0479 0.0578
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0159 0.0416 0.0906
Trichomonas vaginalis AGC family protein kinase 0.0154 0.0385 0.0859
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0117 0.0189 0.0424
Plasmodium falciparum cGMP-dependent protein kinase 0.0159 0.0416 0.1805
Trypanosoma brucei protein kinase, putative 0.0158 0.041 0.0825
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0117 0.0189 0.0189
Echinococcus granulosus dual specificity protein kinase clk2 0.0179 0.0523 0.0635
Plasmodium falciparum serine/threonine protein kinase 0.0106 0.0126 0.007
Echinococcus granulosus mitogen activated protein kinase 11 0.0314 0.1253 0.1588
Giardia lamblia Kinase, AGC PKA 0.0178 0.0516 0.1648
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0286 0.11 0.11
Echinococcus multilocularis dual specificity testis specific protein kinase 0.044 0.1936 0.213
Echinococcus granulosus serine:threonine kinase SAD 1 0.0135 0.0286 0.0326
Brugia malayi Protein kinase domain containing protein 0.0137 0.0294 0.0294
Echinococcus granulosus serine:threonine protein kinase MARK2 0.039 0.1663 0.2124
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0171 0.0479 0.1635
Trichomonas vaginalis CMGC family protein kinase 0.0164 0.0441 0.1018
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0088 0.0007
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0286 0.11 0.2824
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0286 0.11 0.6107
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0088 0.0007
Trypanosoma cruzi casein kinase II, putative 0.0192 0.0593 0.2109
Brugia malayi Immunoglobulin I-set domain containing protein 0.0109 0.0143 0.0143
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.023 0.08 0.08
Onchocerca volvulus 0.0171 0.0479 0.0814
Onchocerca volvulus 0.0127 0.0243 0.0285
Loa Loa (eye worm) hypothetical protein 0.0335 0.1365 0.1365
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.0351 0.0761
Echinococcus multilocularis casein kinase I gamma 0.0241 0.0859 0.0922
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0178 0.0516 0.0626
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0286 0.0575
Echinococcus granulosus tyrosine protein kinase Fyn 0.0305 0.1203 0.1523
Brugia malayi protein-tyrosine kinase 0.0258 0.0952 0.0952
Echinococcus granulosus neuroglian 0.0173 0.049 0.0592
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0251 0.0912 0.3433
Loa Loa (eye worm) AGC/PKA protein kinase 0.0178 0.0516 0.0516
Echinococcus granulosus tyrosine protein kinase Blk 0.0258 0.0952 0.1196
Loa Loa (eye worm) hypothetical protein 0.0148 0.0356 0.0356
Schistosoma mansoni serine/threonine protein kinase 0.0523 0.2385 0.5654
Echinococcus granulosus cGMP dependent protein kinase 1 0.0159 0.0416 0.0495
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Echinococcus multilocularis cyclin dependent kinase 5 0.0231 0.0802 0.0858
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0305 0.1203 0.1308
Entamoeba histolytica protein kinase domain containing protein 0.0192 0.0593 0.1355
Trichomonas vaginalis CAMK family protein kinase 0.0308 0.1219 0.3247
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0098 0.0085 0.0085
Toxoplasma gondii AGC kinase 0.0178 0.0516 0.1206
Mycobacterium ulcerans hypothetical protein 0.0106 0.0126 0.5
Trichomonas vaginalis AGC family protein kinase 0.0743 0.3577 1
Echinococcus multilocularis rho associated protein kinase 0.0657 0.3108 0.3444
Trichomonas vaginalis CAMK family protein kinase 0.0543 0.2495 0.6901
Entamoeba histolytica protein kinase, putative 0.0164 0.0441 0.0913
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0294 0.0294
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0132 0.0266 0.0257
Loa Loa (eye worm) CDC7 protein kinase 0.0113 0.0163 0.0163
Echinococcus granulosus expressed protein 0.0106 0.0126 0.0116
Entamoeba histolytica cell division protein kinase 2, putative 0.0231 0.0802 0.196
Echinococcus granulosus tyrosine protein kinase Src42A 0.0305 0.1203 0.1523
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0179 0.0523 0.1818
Entamoeba histolytica casein kinase 1, putative 0.0171 0.0479 0.1025
Plasmodium falciparum calcium-dependent protein kinase 2 0.0147 0.0351 0.1416
Echinococcus granulosus tyrosine kinase 0.0258 0.0952 0.1196
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0178 0.0516 0.1788
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0266 0.0996 0.5515
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0135 0.0286 0.0677
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0147 0.0351 0.0711
Brugia malayi Protein kinase domain containing protein 0.0113 0.0163 0.0163
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0126 0.0273
Schistosoma mansoni serine/threonine kinase 0.0308 0.1219 0.2877
Trichomonas vaginalis AGC family protein kinase 0.0099 0.0088 0.0007
Plasmodium falciparum casein kinase 2, alpha subunit 0.0192 0.0593 0.2864
Loa Loa (eye worm) AGC/PKG protein kinase 0.0159 0.0416 0.0416
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0163 0.0436 0.0447
Brugia malayi Protein kinase domain containing protein 0.0315 0.1261 0.1261
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0286 0.0575
Echinococcus granulosus tyrosine protein kinase Fyn 0.0305 0.1203 0.1523
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0531 0.2428 0.2428
Echinococcus granulosus cyclin dependent kinase 5 0.0231 0.0802 0.1
Schistosoma mansoni serine/threonine protein kinase 0.036 0.15 0.3546
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0531 0.2428 0.2681
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0135 0.0286 0.0834
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0098 0.0085 0.0085
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0136 0.0292 0.0292
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0136 0.0292 0.0292
Echinococcus granulosus tyrosine protein kinase Fyn 0.0305 0.1203 0.1523
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0136 0.0292 0.0286
Entamoeba histolytica protein kinase, putative 0.0743 0.3577 1
Giardia lamblia Kinase, AGC PKA 0.0413 0.1788 0.7015
Plasmodium falciparum calcium-dependent protein kinase 1 0.0147 0.0351 0.1416
Trichomonas vaginalis AGC family protein kinase 0.0286 0.11 0.2907
Schistosoma mansoni hypothetical protein 0.0169 0.0466 0.1084
Schistosoma mansoni protein kinase 0.0171 0.0479 0.1115
Onchocerca volvulus 0.0251 0.0912 0.1786
Onchocerca volvulus Tyrosine kinase homolog 0.0928 0.4575 1
Trichomonas vaginalis AGC family protein kinase 0.0154 0.0385 0.0859
Loa Loa (eye worm) TK/FER protein kinase 0.0453 0.2004 0.2004
Loa Loa (eye worm) AUR protein kinase 0.0286 0.11 0.11
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0158 0.041 0.1349
Onchocerca volvulus 0.0335 0.1365 0.2801
Echinococcus granulosus casein kinase I gamma 0.0241 0.0859 0.1074
Loa Loa (eye worm) hypothetical protein 0.0644 0.304 0.304
Entamoeba histolytica protein kinase domain containing protein 0.0251 0.0912 0.228
Echinococcus granulosus homeodomain interacting protein kinase 3 0.023 0.08 0.0996
Giardia lamblia Kinase, STE STE20 0.016 0.0421 0.1245
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0136 0.0292 0.0334
Entamoeba histolytica serine/threonine protein kinase, putative 0.0135 0.0286 0.0465
Echinococcus multilocularis tyrosine protein kinase shark 0.0359 0.1498 0.1638
Plasmodium vivax glycogen synthase kinase 3, putative 0.0251 0.0912 0.5043
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0314 0.1253 0.3266
Trypanosoma brucei protein kinase, putative 0.0119 0.0199 0.0212
Echinococcus granulosus casein kinase I alpha 0.0171 0.0479 0.0578
Schistosoma mansoni rap gtpase-activating protein 0.0127 0.0243 0.0553
Echinococcus granulosus tyrosine kinase 0.0137 0.0294 0.0336
Echinococcus granulosus casein kinase i 0.0171 0.0479 0.0578
Loa Loa (eye worm) AUR protein kinase 0.0286 0.11 0.11
Schistosoma mansoni serine/threonine protein kinase 0.039 0.1663 0.3934
Schistosoma mansoni tyrosine kinase 0.0414 0.1796 0.425
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0158 0.041 0.0889
Brugia malayi Protein kinase domain containing protein 0.0412 0.1785 0.1785
Plasmodium falciparum calcium-dependent protein kinase 4 0.0147 0.0351 0.1416
Plasmodium falciparum protein serine/threonine kinase-1 0.0179 0.0523 0.2446
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0178 0.0516 0.0537
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0136 0.0292 0.0286
Brugia malayi phosphoinositide-dependent protein kinase I 0.0154 0.0385 0.0385
Brugia malayi serine/threonine-protein kinase 6 0.0286 0.11 0.11
Loa Loa (eye worm) hypothetical protein 0.0286 0.1104 0.1104
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0136 0.0292 0.0286
Brugia malayi Protein kinase domain containing protein 0.0137 0.0294 0.0294
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0494 0.2229 0.2458
Brugia malayi Furin-like cysteine rich region family protein 0.086 0.421 0.421
Echinococcus granulosus nervana 2 0.0359 0.1498 0.1909
Loa Loa (eye worm) hypothetical protein 0.017 0.0475 0.0475
Brugia malayi Cation transporter family protein 0.0136 0.0292 0.0292
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0516 0.2345 0.2345
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0305 0.1203 0.1308
Plasmodium falciparum casein kinase 1 0.0171 0.0479 0.2183
Giardia lamblia Kinase, CMGC GSK 0.0251 0.0912 0.3321
Brugia malayi Protein kinase domain containing protein 0.0579 0.2688 0.2688
Brugia malayi serine/threonine-protein kinase PAK 7 0.0464 0.2068 0.2068
Plasmodium vivax serine/threonine protein kinase, putative 0.0106 0.0126 0.0586
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0251 0.0912 0.2396
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0127 0.0243 0.0656
Loa Loa (eye worm) hypothetical protein 0.0127 0.0243 0.0243
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0163 0.0436 0.0521
Trypanosoma cruzi casein kinase, putative 0.0171 0.0479 0.1635
Echinococcus multilocularis Immunoglobulin 0.0136 0.0291 0.0285
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0192 0.0593 0.0593
Trichomonas vaginalis CMGC family protein kinase 0.0231 0.0802 0.2053
Echinococcus multilocularis titin 0.0109 0.0143 0.0119
Loa Loa (eye worm) hypothetical protein 0.0136 0.0291 0.0291
Brugia malayi Immunoglobulin I-set domain containing protein 0.0089 0.0037 0.0037
Echinococcus multilocularis dual specificity 0.0164 0.0441 0.0453
Echinococcus multilocularis serine:threonine protein kinase N2 0.036 0.1503 0.1644
Toxoplasma gondii AGC kinase 0.0178 0.0516 0.1206
Loa Loa (eye worm) hypothetical protein 0.0311 0.1236 0.1236
Schistosoma mansoni serine/threonine protein kinase 0.039 0.1663 0.3934
Schistosoma mansoni tyrosine kinase 0.0662 0.3139 0.745
Brugia malayi Protein kinase domain containing protein 0.0137 0.0294 0.0294
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0534 0.2442 0.2442
Trichomonas vaginalis CK1 family protein kinase 0.0171 0.0479 0.1128
Echinococcus multilocularis mitogen activated protein kinase 0.0158 0.041 0.0419
Trichomonas vaginalis CAMK family protein kinase 0.0221 0.075 0.1903
Schistosoma mansoni tyrosine kinase 0.0509 0.231 0.5476
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0294 0.0294
Echinococcus multilocularis serine:threonine protein kinase N2 0.0135 0.0284 0.0278
Echinococcus granulosus NDR protein kinase 0.036 0.1503 0.1915
Echinococcus granulosus protein kinase 0.0179 0.0521 0.0632
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0593 0.1455
Giardia lamblia Kinase, CDC7 0.0113 0.0163 0.0159
Brugia malayi Cation transporter family protein 0.0136 0.0292 0.0292
Onchocerca volvulus 0.0136 0.0292 0.0395
Plasmodium falciparum NIMA related kinase 1 0.0266 0.0996 0.527
Brugia malayi Protein kinase domain containing protein 0.0106 0.0126 0.0126
Schistosoma mansoni ephrin receptor 0.0198 0.0625 0.1462
Onchocerca volvulus 0.0137 0.0294 0.0398
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0178 0.0516 0.0626
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0163 0.0436 0.0447
Brugia malayi Protein kinase domain containing protein 0.0743 0.3577 0.3577
Onchocerca volvulus 0.0137 0.0294 0.0398
Brugia malayi ephrin receptor 1 precursor 0.0128 0.0246 0.0246
Loa Loa (eye worm) AGC/PKN protein kinase 0.0495 0.2233 0.2233
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0164 0.0441 0.0441
Echinococcus granulosus ephrin type A receptor 4 A 0.0198 0.0625 0.0768
Trichomonas vaginalis CMGC family protein kinase 0.0164 0.0441 0.1018
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0453 0.2004 0.257
Loa Loa (eye worm) hypothetical protein 0.0136 0.0292 0.0292
Brugia malayi Protein kinase domain containing protein 0.0084 0.0006 0.0006
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0106 0.0126 0.0035
Schistosoma mansoni nAChR subunit 0.0136 0.0292 0.067
Schistosoma mansoni tyrosine kinase 0.0282 0.1079 0.2543
Echinococcus granulosus growth factor receptor bound protein 2 0.0119 0.02 0.0213
Trypanosoma cruzi casein kinase, putative 0.0171 0.0479 0.1635
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0305 0.1203 0.1308
Echinococcus multilocularis death associated protein kinase 1 0.1737 0.8954 1
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0593 0.1455
Giardia lamblia Kinase, CMGC CLK 0.0179 0.0523 0.1679
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0353 0.1463 0.16
Schistosoma mansoni protein kinase 0.0163 0.0436 0.1012
Trypanosoma cruzi cdc2-related kinase 3 0.0231 0.0802 0.2975
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0413 0.1788 1

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 186 nM In vitro inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptor ChEMBL. 12617929
IC50 (binding) = 186 nM In vitro inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETA receptor ChEMBL. 12617929
IC50 (binding) = 903 nM In vitro inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptor ChEMBL. 12617929
IC50 (binding) = 903 nM In vitro inhibitory concentration required against [125I]-ET-1 binding to membranes of CHO cells expressing human ETB receptor ChEMBL. 12617929

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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