Detailed information for compound 328261

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 368.82 | Formula: C18H17ClN6O
  • H donors: 3 H acceptors: 4 LogP: 3.97 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCNc1ccc2c(n1)n1cncc1c(n2)Nc1c(C)cccc1Cl
  • InChi: 1S/C18H17ClN6O/c1-11-3-2-4-12(19)16(11)24-17-14-9-20-10-25(14)18-13(22-17)5-6-15(23-18)21-7-8-26/h2-6,9-10,26H,7-8H2,1H3,(H,21,23)(H,22,24)
  • InChiKey: PDDJFHPVBWPORY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans penicillin-binding lipoprotein 0.0785 0.301 0.3372
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.022 0.0796 0.6153
Loa Loa (eye worm) SMO-1 protein 0.0063 0.0181 0.055
Trypanosoma brucei DNA polymerase kappa, putative 0.0203 0.073 0.5641
Echinococcus granulosus pyruvate kinase 0.0017 0.0004 0.0005
Mycobacterium ulcerans lipase LipD 0.0073 0.0221 0.0247
Trichomonas vaginalis phosphofructokinase, putative 0.022 0.0796 0.1527
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.0026 0.0031
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0068 0.0525
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0077 0.0238 0.0724
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0122 0.0413 0.0506
Trypanosoma brucei phosphoglycerate kinase 0.0127 0.0435 0.336
Mycobacterium tuberculosis Probable penicillin-binding membrane protein PbpB 0.0672 0.2564 0.4546
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0018 0.002
Brugia malayi Thioredoxin reductase 0.0048 0.0123 0.0371
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0077 0.0238 0.0721
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0171 0.0605 0.1838
Loa Loa (eye worm) hypothetical protein 0.0347 0.1294 0.393
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0015 0.0019
Echinococcus multilocularis pyruvate kinase 0.0034 0.0068 0.0083
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0183 0.0653 0.08
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0155 0.0297
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0015 0.0019
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.003 0.0051
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0277 0.1022 0.79
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0017 0.0001 0.0001
Plasmodium falciparum nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.0288 0.1064 0.8226
Schistosoma mansoni polycystin 1-related 0.002 0.0015 0.0017
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.119 0.4591 1
Mycobacterium leprae Probable penicillin-binding protein PbpA 0.1457 0.5639 1
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0192 0.0689 0.2089
Brugia malayi beta-lactamase 0.0073 0.0221 0.0669
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0001 0.001
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0021 0.002 0.0058
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0347 0.1294 1
Brugia malayi Variant SH3 domain containing protein 0.0128 0.0439 0.133
Echinococcus granulosus chromobox protein 2 0.0023 0.0026 0.0032
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0018 0.005
Brugia malayi polk-prov protein 0.0119 0.0401 0.1215
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0581 0.221 0.3918
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0018 0.0022
Treponema pallidum phosphoglycerate kinase 0.0347 0.1294 0.1293
Schistosoma mansoni 6-phosphofructokinase 0.022 0.0796 0.0974
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0035
Leishmania major DNA damage repair protein, putative 0.0038 0.0084 0.0653
Brugia malayi ImpB/MucB/SamB family protein 0.0173 0.0614 0.1863
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0183 0.0653 0.1156
Loa Loa (eye worm) hypothetical protein 0.002 0.0016 0.0048
Mycobacterium tuberculosis Conserved hypothetical protein 0.0122 0.0413 0.0731
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0066 0.0194 0.1498
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.0011 0.0079
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0149 0.0454
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0039 0.0048
Mycobacterium tuberculosis Probable bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 (murein polymerase) [includes: penicillin-insen 0.1079 0.4157 0.7371
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0039 0.0083
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0018 0.002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0221 0.027
Brugia malayi Matrixin family protein 0.0043 0.0103 0.0309
Mycobacterium tuberculosis Probable penicillin-binding protein PbpA 0.1457 0.5639 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0018 0.005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0001 0.001
Giardia lamblia Pyruvate kinase 0.0017 0.0004 0.0008
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0018 0.0022
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0127 0.0435 0.336
Trypanosoma cruzi DNA polymerase eta, putative 0.0089 0.0286 0.2207
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0026 0.0051
Schistosoma mansoni transcription factor btf3 0.0035 0.0075 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0051
Echinococcus multilocularis L aminoadipate semialdehyde 0.0085 0.027 0.033
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0008 0.0019
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0122 0.0413 0.0506
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0123 0.0954
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0011 0.0014
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0142 0.0492 0.087
Giardia lamblia Sirtuin type 2 0.0017 0.0001 0.0003
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0021 0.002 0.0061
Brugia malayi intermediate filament protein 0.0054 0.0149 0.045
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0015 0.0019
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0026 0.0195
Trypanosoma brucei DNA polymerase IV, putative 0.0203 0.073 0.5641
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0127 0.0435 0.336
Schistosoma mansoni pyruvate kinase 0.0034 0.0068 0.0082
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0017 0.0001 0.0002
Mycobacterium ulcerans DNA polymerase IV 0.0203 0.073 0.0817
Giardia lamblia Sentrin 0.0063 0.0181 0.0394
Echinococcus granulosus histone lysine methyltransferase setb 0.0123 0.0418 0.0512
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.008
Echinococcus granulosus Small ubiquitin modifier 2 0.0063 0.0181 0.0222
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0001 0.001
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0018 0.002
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0011 0.0014
Toxoplasma gondii ABC1 family protein 0.0073 0.0221 0.1702
Loa Loa (eye worm) hypothetical protein 0.0119 0.0401 0.1218
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0001 0.001
Leishmania major phospholipase c-like protein 0.0019 0.0009 0.0072
Schistosoma mansoni 6-phosphofructokinase 0.022 0.0796 0.0974
Schistosoma mansoni coup transcription factor 0.0021 0.0018 0.002
Trypanosoma brucei unspecified product 0.0084 0.0265 0.2051
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0068 0.0167
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.119 0.4591 0.8806
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0052 0.014 0.0269
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0017 0.0001 0.0002
Plasmodium vivax JmjC domain containing protein 0.0019 0.0011 0.0079
Loa Loa (eye worm) glutaminase 2 0.0556 0.2112 0.6417
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0066 0.0194 0.1498
Brugia malayi Doublecortin family protein 0.002 0.0015 0.0043
Mycobacterium leprae Probable NAD-dependent deacetylase NpdA (Regulatory protein SIR2 homolog) 0.0035 0.0075 0.0105
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.005 0.015
Schistosoma mansoni ap endonuclease 0.006 0.017 0.0207
Echinococcus granulosus ubiquitin 0.0022 0.0022 0.0027
Toxoplasma gondii histone deacetylase SIR2-like 0.0017 0.0001 0.0001
Wolbachia endosymbiont of Brugia malayi cell division protein FtsI 0.2572 1 1
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0068 0.0516
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0001 0.0002
Plasmodium vivax NAD-dependent deacetylase, putative 0.0052 0.014 0.1074
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0347 0.1294 0.2482
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0018 0.005
Leishmania major hypothetical protein, conserved 0.0059 0.0168 0.1301
Entamoeba histolytica hypothetical protein 0.0024 0.003 0.0063
Mycobacterium leprae Probable transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) 0.0161 0.0566 0.0979
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0347 0.1294 0.1293
Toxoplasma gondii exonuclease III APE 0.006 0.017 0.1309
Echinococcus granulosus caspase 2 0.0031 0.0059 0.0072
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0018 0.002
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0011 0.0014
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0011 0.0035
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0084 0.0653
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0053
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0178
Trypanosoma cruzi small ubiquitin protein, putative 0.0063 0.0181 0.14
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0026 0.0055
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.017 0.1309
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0023
Leishmania major hypothetical protein, conserved 0.0019 0.0011 0.0089
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0039 0.0305
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0169 0.1297
Trichomonas vaginalis set domain proteins, putative 0.0976 0.3755 0.7203
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0068 0.0203
Brugia malayi glutaminase DH11.1 0.0556 0.2112 0.6415
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0012 0.0086
Loa Loa (eye worm) hypothetical protein 0.0073 0.0221 0.0672
Plasmodium falciparum thioredoxin reductase 0.0048 0.0123 0.0946
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0027 0.004 0.0303
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0127 0.0435 0.336
Plasmodium falciparum glutathione reductase 0.0048 0.0123 0.0946
Brugia malayi jmjC domain containing protein 0.0019 0.0011 0.0031
Loa Loa (eye worm) 6-phosphofructokinase 0.022 0.0796 0.2418
Mycobacterium leprae PROBABLE HYDROLASE 0.0021 0.002 0.0008
Plasmodium vivax nicotinate-nucleotide adenylyltransferase, putative 0.0288 0.1064 0.8226
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.022 0.0796 0.1388
Mycobacterium ulcerans bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein 0.0288 0.1064 0.1192
Onchocerca volvulus 0.0085 0.027 0.0705
Echinococcus multilocularis jumonji domain containing protein 0.0083 0.026 0.0319
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0026 0.0051
Echinococcus multilocularis Small ubiquitin modifier 2 0.0063 0.0181 0.0222
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.003 0.0032
Trichomonas vaginalis rotamase, putative 0.0067 0.02 0.0384
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0021 0.002 0.0057
Mycobacterium tuberculosis Conserved protein 0.0073 0.0221 0.039
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0068 0.0206
Brugia malayi jmjC domain containing protein 0.0019 0.0011 0.0031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0018 0.0053
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.006 0.017 0.1317
Brugia malayi jmjC domain containing protein 0.0019 0.0011 0.0031
Entamoeba histolytica ubiquitin like protein 0.0063 0.0181 0.0392
Trypanosoma brucei DNA damage repair protein, putative 0.0038 0.0084 0.0653
Brugia malayi Pre-SET motif family protein 0.0123 0.0418 0.1266
Plasmodium vivax DNA repair protein REV1, putative 0.0038 0.0084 0.0644
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0079 0.0245 0.0638
Schistosoma mansoni rab6-interacting 0.002 0.0015 0.0017
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0001 0.001
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0018 0.0053
Brugia malayi Matrixin family protein 0.0018 0.0005 0.0012
Echinococcus granulosus RUN 0.002 0.0015 0.0019
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0068 0.0167
Echinococcus granulosus chromobox protein 1 0.0141 0.0486 0.0596
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.003 0.0032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0035
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0038 0.0084 0.0644
Echinococcus multilocularis transcription factor btf3 0.0035 0.0075 0.0091
Entamoeba histolytica hypothetical protein 0.0035 0.0075 0.016
Plasmodium falciparum JmjC domain-containing protein, putative 0.0019 0.0011 0.0079
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.008
Onchocerca volvulus Matrilysin homolog 0.0039 0.0089 0.0224
Loa Loa (eye worm) hypothetical protein 0.0023 0.0028 0.0085
Loa Loa (eye worm) transcriptional regulator 0.0017 0.0001 0.0004
Leishmania major pyruvate kinase 0.0034 0.0068 0.0525
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0221 0.039
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0064 0.0187 0.0229
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0238 0.1835
Schistosoma mansoni DNA helicase recq5 0.003 0.0054 0.0064
Trichomonas vaginalis esterase, putative 0.0073 0.0221 0.0424
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0026 0.0051
Leishmania major pyruvate kinase 0.0034 0.0068 0.0525
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0239 0.0871 0.2645
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0016
Onchocerca volvulus 0.0021 0.0018 0.0033
Leishmania major sir2-family protein-like protein 0.0017 0.0001 0.0011
Brugia malayi jmjC domain containing protein 0.0019 0.0011 0.0031
Trichomonas vaginalis phosphofructokinase, putative 0.022 0.0796 0.1527
Loa Loa (eye worm) matrix metalloproteinase 0.0018 0.0005 0.0016
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0363 0.0642
Trichomonas vaginalis glutaminase, putative 0.0556 0.2112 0.4052
Trichomonas vaginalis ubiquitin, putative 0.0022 0.0022 0.0042
Loa Loa (eye worm) hypothetical protein 0.0039 0.009 0.0274
Treponema pallidum fructose-bisphosphate aldolase 0.119 0.4591 0.459
Loa Loa (eye worm) hypothetical protein 0.0058 0.0161 0.049
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0051
Loa Loa (eye worm) hypothetical protein 0.0102 0.0335 0.1018
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0052 0.014 0.0302
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0018 0.0022
Giardia lamblia Fructose-bisphosphate aldolase 0.119 0.4591 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0011 0.0014
Brugia malayi 6-phosphofructokinase 0.022 0.0796 0.2416
Schistosoma mansoni DNA polymerase eta 0.0173 0.0614 0.0751
Echinococcus granulosus expressed protein 0.0067 0.02 0.0245
Brugia malayi Phosphoglycerate kinase 0.0127 0.0435 0.1317
Loa Loa (eye worm) jmjC domain-containing protein 0.0123 0.0416 0.1265
Mycobacterium ulcerans bifunctional penicillin-binding protein 1A/1B PonA1 0.1349 0.5213 0.5842
Toxoplasma gondii 6-phosphofructokinase 0.0059 0.0169 0.1295
Brugia malayi Associated with TFs and helicases family protein 0.0023 0.0026 0.0077
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0084 0.0653
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0221 0.039
Leishmania major silent information regulator 2, putative 0.0017 0.0001 0.0011
Brugia malayi PHD-finger family protein 0.0059 0.0169 0.051
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.003 0.0029
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0001 0.001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.003 0.0035
Loa Loa (eye worm) hypothetical protein 0.0021 0.002 0.0062
Brugia malayi steroid hormone receptor 0.0021 0.0018 0.005
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0001 0.0003
Echinococcus granulosus neuropeptide s receptor 0.047 0.1774 0.2174
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0064 0.0187 0.0229
Onchocerca volvulus 0.0025 0.0034 0.0077
Treponema pallidum penicillin-binding protein (pbp-1) 0.2572 1 1
Entamoeba histolytica phosphoglycerate kinase, putative 0.0347 0.1294 0.2816
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.005 0.0153
Giardia lamblia Transcriptional regulator, Sir2 family 0.0052 0.014 0.0305
Plasmodium vivax 6-phosphofructokinase, putative 0.0059 0.0169 0.1295
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0085 0.0268 0.0701
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0011 0.0014
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.0363 0.0642
Echinococcus granulosus lamin dm0 0.0054 0.0149 0.0183
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0059 0.0169 0.1295
Mycobacterium leprae PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC 0.0288 0.1064 0.1865
Plasmodium vivax small ubiquitin-related modifier, putative 0.0063 0.0181 0.1391
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0192 0.0689 0.1321
Loa Loa (eye worm) hypothetical protein 0.0132 0.0454 0.1379
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0001 0.0003
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0008 0.0009
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0221 0.0672
Mycobacterium ulcerans NAD-dependent deacetylase 0.0052 0.014 0.0156
Giardia lamblia DINP protein human, muc B family 0.0142 0.0492 0.1071
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0018 0.0022
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0026 0.0051
Trypanosoma brucei DNA polymerase kappa, putative 0.0203 0.073 0.5641
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.003 0.0054 0.0159
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.0418 0.051
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0018 0.0022
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0039 0.0296
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0018 0.005
Loa Loa (eye worm) hypothetical protein 0.0053 0.0145 0.0442
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0026 0.0055
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0059 0.0168 0.0323
Echinococcus granulosus pyruvate kinase 0.0034 0.0068 0.0083
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.0363 0.0618
Mycobacterium ulcerans bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 0.1079 0.4157 0.4658
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0068 0.0525
Leishmania major phosphatidylinositol-specific phospholipase-like protein 0.0018 0.0005 0.004
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0018 0.005
Brugia malayi nuclear receptor NHR-88 0.0021 0.0018 0.005
Echinococcus granulosus neuropeptide receptor A26 0.047 0.1774 0.2174
Echinococcus multilocularis Chromobox protein 3 0.0023 0.0026 0.0032
Leishmania major small ubiquitin protein, putative 0.0063 0.0181 0.14
Schistosoma mansoni loxhd1 0.002 0.0015 0.0017
Trypanosoma cruzi DNA damage repair protein, putative 0.0038 0.0084 0.0653
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0195 0.0698 0.0855
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0039 0.0296
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.003 0.0054 0.0066
Trichomonas vaginalis ap endonuclease, putative 0.006 0.017 0.0327
Echinococcus granulosus bloom syndrome protein 0.0044 0.0109 0.0134
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.002 0.0017 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0051
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0018 0.0022
Echinococcus granulosus phosphoglycerate kinase 1 0.0347 0.1294 0.1585
Echinococcus granulosus 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 0.0019 0.0009 0.0011
Chlamydia trachomatis transglycolase/transpeptidase 0.1182 0.4562 0.4561
Loa Loa (eye worm) hypothetical protein 0.0079 0.0245 0.0743
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0039 0.0305
Brugia malayi chromobox protein homolog 3 0.0079 0.0245 0.074
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0133 0.0457 0.0808
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.009 0.027
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0123 0.0151
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0018 0.005
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0075 0.0577
Toxoplasma gondii phosphoinositide phospholipase PIPLC 0.0019 0.0009 0.0062
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.119 0.4591 1
Echinococcus granulosus Chromobox protein 3 0.0023 0.0026 0.0032
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.003 0.0223
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0018 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0026 0.0051
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0169 0.0324
Leishmania major DNA polymerase kappa, putative 0.0038 0.0084 0.0653
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0221 0.0669
Echinococcus multilocularis pyruvate kinase 0.0034 0.0068 0.0083
Mycobacterium ulcerans epimerase 0.002 0.0016 0.0016
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0011 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0018 0.005
Echinococcus granulosus phd:f box containing protein 0.0019 0.0011 0.0014
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0054 0.0406
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.02 0.0384
Onchocerca volvulus 0.0073 0.0221 0.0576
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0347 0.1294 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0058 0.0161 0.0487
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.119 0.4591 0.8806
Schistosoma mansoni phospholipase C beta 0.0018 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0245 0.0469
Brugia malayi 6-phosphofructokinase 0.022 0.0796 0.2416
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.0068 0.0093
Brugia malayi Protein cec-1. 0.0023 0.0026 0.0077
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.119 0.4591 0.8806
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0183 0.0653 0.0731
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0181 0.0347
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0123 0.0946
Trypanosoma brucei phosphoglycerate kinase 0.0347 0.1294 1
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0067 0.02 0.0608
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0077 0.0238 0.0421
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0277 0.1022 0.3105
Trypanosoma brucei phosphoglycerate kinase 0.0347 0.1294 1
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0066 0.0194 0.1498
Entamoeba histolytica phosphofructokinase, putative 0.022 0.0796 0.1732
Loa Loa (eye worm) hypothetical protein 0.0073 0.0221 0.0672
Onchocerca volvulus Cell death protein 3 homolog 0.0031 0.0059 0.0142
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0021 0.002 0.0057
Echinococcus granulosus PHD finger protein rhinoceros 0.0059 0.0169 0.0207
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0039 0.0305
Brugia malayi Pre-SET motif family protein 0.0858 0.3292 1
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0059 0.0169 0.0324
Schistosoma mansoni flap endonuclease-1 0.0024 0.003 0.0035
Toxoplasma gondii thioredoxin reductase 0.0048 0.0123 0.0946
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0026 0.0051
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0011 0.0089
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0016 0.0044
Toxoplasma gondii phosphofructokinase PFKII 0.0059 0.0169 0.1295
Plasmodium falciparum heterochromatin protein 1 0.0023 0.0026 0.0195
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0053
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0068 0.013
Echinococcus granulosus microtubule associated protein 2 0.2102 0.8161 1
Onchocerca volvulus Alhambra homolog 0.0059 0.0169 0.0436
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0001 0.0003
Mycobacterium ulcerans penicillin-binding membrane protein PbpB 0.2297 0.8923 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0123 0.0418 0.3222
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0015 0.011
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0001 0.001
Schistosoma mansoni chromatin regulatory protein sir2 0.0052 0.014 0.017
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0017 0.0001 0.0011
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0026 0.0051
Trypanosoma brucei DNA polymerase IV, putative 0.0203 0.073 0.5641
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0011 0.0035
Trypanosoma cruzi DNA damage repair protein, putative 0.0038 0.0084 0.0653
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0183 0.0653 0.0799
Loa Loa (eye worm) matrixin family protein 0.0039 0.0089 0.0271
Loa Loa (eye worm) hypothetical protein 0.0062 0.0178 0.0541
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0066 0.0194 0.0419
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0018 0.0053
Brugia malayi Valyl-tRNA synthetase 0.0023 0.0026 0.0077
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0059 0.0168 0.1301
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0221 0.027
Schistosoma mansoni hypothetical protein 0.0039 0.009 0.0109
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0192 0.0689 0.1321
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0001 0.001
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0018 0.0022
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.002 0.0017 0.0128
Trichomonas vaginalis DNA polymerase eta, putative 0.0203 0.073 0.14
Plasmodium falciparum phosphoglycerate kinase 0.0347 0.1294 1
Echinococcus multilocularis pyruvate kinase 0.0017 0.0004 0.0005
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0347 0.1294 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0183 0.0653 0.5048
Schistosoma mansoni DNA polymerase IV / kappa 0.0038 0.0084 0.0102
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0058 0.0161 0.0487
Giardia lamblia Pyruvate kinase 0.0034 0.0068 0.0148
Brugia malayi AF-10 protein 0.0019 0.0012 0.0034
Trypanosoma cruzi DNA polymerase kappa, putative 0.0203 0.073 0.5641
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.003 0.0223
Brugia malayi PHD-finger family protein 0.0019 0.0012 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.1349 0.5213 1
Loa Loa (eye worm) RecQ helicase 0.0044 0.0109 0.0332
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0017 0.0001 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0018 0.0022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0026 0.0051
Echinococcus granulosus transcription factor btf3 0.0035 0.0075 0.0091
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0011 0.0013
Schistosoma mansoni pyruvate kinase 0.0017 0.0004 0.0003
Schistosoma mansoni chromobox protein 0.0023 0.0026 0.0031
Echinococcus multilocularis ubiquitin 0.0022 0.0022 0.0027
Trypanosoma brucei DNA damage repair protein, putative 0.0038 0.0084 0.0653
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0018 0.0053
Schistosoma mansoni hypothetical protein 0.002 0.0015 0.0017
Onchocerca volvulus Matrix metalloproteinase homolog 0.0039 0.0089 0.0224
Onchocerca volvulus 0.0054 0.0149 0.0384
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0028 0.0058
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0001 0.001
Schistosoma mansoni microtubule-associated protein tau 0.2102 0.8161 1
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0059 0.0168 0.0323
Echinococcus multilocularis phosphoglycerate kinase 1 0.0347 0.1294 0.1585
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0016 0.0028
Mycobacterium tuberculosis Probable reductase 0.0109 0.0363 0.0642
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0065 0.0504
Brugia malayi Ubiquitin-like protein SMT3 0.0063 0.0181 0.0547
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0169 0.0324
Entamoeba histolytica exodeoxyribonuclease III, putative 0.006 0.017 0.0368
Mycobacterium leprae conserved hypothetical protein 0.0024 0.003 0.0025
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0023 0.0026 0.0032
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0123 0.0418 0.0512
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0018 0.0033
Echinococcus multilocularis pyruvate kinase 0.0027 0.004 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0344 0.2658
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0065 0.0504
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.022 0.0796 0.6153
Brugia malayi hypothetical protein 0.0022 0.0022 0.0063
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0347 0.1294 0.2273
Trypanosoma brucei DNA polymerase IV, putative 0.0183 0.0651 0.5034
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0051
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0026 0.0055
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0221 0.0424
Echinococcus granulosus 6 phosphofructokinase 0.022 0.0796 0.0975
Echinococcus granulosus pyruvate kinase 0.0017 0.0004 0.0005
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0038 0.0285
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0026 0.0051
Onchocerca volvulus 0.0022 0.0022 0.0044
Mycobacterium leprae Probable lipase LipE 0.0073 0.0221 0.0365
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0018 0.002
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0001 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0203 0.073 0.5641
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0075 0.0568
Loa Loa (eye worm) hypothetical protein 0.0025 0.0035 0.0107
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0123 0.0418 0.0512
Brugia malayi ImpB/MucB/SamB family protein 0.0122 0.0413 0.1252
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0001 0.0003
Echinococcus multilocularis 1 phosphatidylinositol 4,5 bisphosphate 0.0019 0.0009 0.0011
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0004 0.0021
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0017 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0028
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0192 0.0689 0.1321
Mycobacterium tuberculosis Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) 0.0161 0.0566 0.1002
Plasmodium falciparum pyruvate kinase 0.0034 0.0068 0.0516
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.008
Echinococcus granulosus chromatin regulatory protein sir2 0.0017 0.0001 0.0002
Echinococcus multilocularis dna polymerase eta 0.0173 0.0614 0.0753
Mycobacterium tuberculosis Conserved protein 0.0073 0.0221 0.039
Echinococcus multilocularis pyruvate kinase 0.0017 0.0004 0.0005
Echinococcus multilocularis geminin 0.0342 0.1274 0.1561
Echinococcus multilocularis dna polymerase kappa 0.0203 0.073 0.0894
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.0026 0.0195
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0169 0.0324
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0183 0.0653 0.08
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0018 0.005
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0118 0.04 0.049
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0011 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.022 0.0796 0.1527
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0221 0.171
Trichomonas vaginalis phosphofructokinase, putative 0.022 0.0796 0.1527
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0221 0.0424
Trichomonas vaginalis rotamase, putative 0.0066 0.0194 0.0372
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0142 0.0492 0.3802
Schistosoma mansoni hypothetical protein 0.0342 0.1274 0.156
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0581 0.221 0.2476
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.008
Echinococcus multilocularis Chromo domain 0.0023 0.0026 0.0032
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0018 0.0022
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.119 0.4591 0.8806
Schistosoma mansoni hypothetical protein 0.0342 0.1274 0.156
Trypanosoma brucei phosphoinositide-specific phospholipase C 0.0019 0.0009 0.0072
Giardia lamblia Phosphoglycerate kinase 0.0347 0.1294 0.2818
Leishmania major hypothetical protein, conserved 0.0073 0.0221 0.171
Echinococcus multilocularis lysine specific demethylase 5A 0.0072 0.0218 0.0267
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.002 0.0017 0.0128
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0347 0.1294 0.2482
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0018 0.005
Trichomonas vaginalis chromobox protein, putative 0.0085 0.0268 0.0514
Onchocerca volvulus 0.0073 0.0221 0.0576
Treponema pallidum penicillin-binding protein (pbp-2) 0.1349 0.5213 0.5213
Schistosoma mansoni intermediate filament proteins 0.0054 0.0149 0.0181
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0018 0.0022
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.119 0.4591 0.8806
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.0109 0.021
Trypanosoma cruzi small ubiquitin protein, putative 0.0063 0.0181 0.14
Toxoplasma gondii small ubiquitin family modifier, putative 0.0063 0.0181 0.1391
Trypanosoma cruzi hypothetical protein, conserved 0.0059 0.0168 0.1301
Loa Loa (eye worm) hypothetical protein 0.0173 0.0614 0.1867
Echinococcus granulosus transcription factor Dp 1 0.0161 0.0565 0.0692
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0008 0.0009
Trichomonas vaginalis DNA helicase recq, putative 0.0033 0.0065 0.0125
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0001 0.001
Loa Loa (eye worm) hypothetical protein 0.0073 0.0221 0.0672
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0015 0.0019
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0023 0.0026 0.0195
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.006 0.017 0.1317
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0023 0.0026 0.0031
Loa Loa (eye worm) Plcb4 protein 0.0018 0.0005 0.0016
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.017 0.1309
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.003 0.0029
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0017 0.0001 0.0002
Leishmania major DNA polymerase eta, putative 0.0173 0.0614 0.4749
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0277 0.1022 0.1252
Schistosoma mansoni chromobox protein 0.0141 0.0486 0.0595
Loa Loa (eye worm) hypothetical protein 0.0059 0.0169 0.0513
Loa Loa (eye worm) glutathione reductase 0.0048 0.0123 0.0375
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0075 0.0568
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0018 0.005
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.003 0.0223
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0018 0.002
Schistosoma mansoni DNA helicase recq1 0.003 0.0054 0.0064
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.0026 0.0195
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0128 0.0439 0.1333
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0221 0.0247
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.0411 0.0702
Entamoeba histolytica deoxycytidyl transferase, putative 0.0122 0.0413 0.0898
Echinococcus multilocularis chromobox protein 2 0.0023 0.0026 0.0032
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0277 0.1022 0.79
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.119 0.4591 0.8806
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0052 0.014 0.0246
Toxoplasma gondii peptidylprolyl isomerase 0.0066 0.0194 0.149
Trypanosoma brucei unspecified product 0.0183 0.0651 0.5034
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0017 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0053
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0004
Treponema pallidum hypothetical protein 0.0161 0.0566 0.0565
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0169 0.0324
Echinococcus granulosus dna polymerase kappa 0.0203 0.073 0.0894
Schistosoma mansoni phosphoglycerate kinase 0.0347 0.1294 0.1584
Onchocerca volvulus 0.0054 0.0149 0.0384
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0121 0.0409 0.0501
Onchocerca volvulus 0.0019 0.0009 0.0011
Loa Loa (eye worm) CHromoDomain protein family member 0.0023 0.0026 0.008
Echinococcus granulosus apoptotic protease activating factor 1 0.0031 0.0059 0.0072
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0059 0.0169 0.1295
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0018 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0022 0.0042
Echinococcus multilocularis musashi 0.0054 0.0149 0.0183
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0011 0.0089
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0011 0.0013
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0015 0.0019
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0052 0.014 0.1083
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0052 0.014 0.0269
Schistosoma mansoni terminal deoxycytidyl transferase 0.0122 0.0413 0.0505
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0084 0.0653
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0053
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0075 0.0568
Trypanosoma brucei DNA polymerase eta, putative 0.0173 0.0614 0.4749
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0011 0.0089
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0001 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0203 0.073 0.5641
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0221 0.039
Schistosoma mansoni hypothetical protein 0.0019 0.0012 0.0014
Plasmodium vivax phospholipase C-like, putative 0.0018 0.0005 0.003
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0001 0.0003
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0123 0.0151
Loa Loa (eye worm) helicase 0.0023 0.0026 0.008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0053
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0581 0.221 0.3902
Brugia malayi beta-NAC-like protein 0.0035 0.0075 0.0223
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.003 0.0233
Mycobacterium tuberculosis Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic 0.0288 0.1064 0.1886
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0221 0.039
Echinococcus multilocularis PHD finger protein rhinoceros 0.0059 0.0169 0.0207
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0085 0.027 0.0815
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0018 0.0022
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0023 0.0026 0.0195
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0039 0.0076
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0221 0.0424
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0039 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0492 0.3802
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0018 0.0033
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0018 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0245 0.0469
Leishmania major ATP-dependent phosphofructokinase 0.022 0.0796 0.6153
Onchocerca volvulus 0.002 0.0015 0.0027
Onchocerca volvulus 0.002 0.0015 0.0027
Echinococcus multilocularis apoptotic protease activating factor 1 0.0031 0.0059 0.0072
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0042 0.01 0.0121
Schistosoma mansoni jumonji/arid domain-containing protein 0.0072 0.0218 0.0265
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0052 0.014 0.0269
Echinococcus multilocularis pyruvate kinase 0.0017 0.0004 0.0005
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0122 0.0413 0.1256
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.0363 0.0642
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0051
Trypanosoma brucei DNA polymerase kappa, putative 0.0203 0.073 0.5641
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0123 0.0217
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.003 0.0233
Echinococcus multilocularis caspase 2 0.0031 0.0059 0.0072
Echinococcus granulosus chromobox protein 1 0.0141 0.0486 0.0596
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0017 0.0001 0.0002
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0021 0.002 0.0034
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.022 0.0796 0.141
Trypanosoma brucei DNA polymerase kappa, putative 0.0203 0.073 0.5641
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0363 0.0642
Loa Loa (eye worm) matrixin family protein 0.0043 0.0103 0.0313
Plasmodium falciparum flap endonuclease 1 0.0026 0.0039 0.0296
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.008
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.006 0.017 0.0518
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0019 0.0012 0.0086
Trypanosoma brucei phosphoglycerate kinase, putative 0.0127 0.0435 0.336
Schistosoma mansoni caspase-7 (C14 family) 0.0031 0.0059 0.007
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0068 0.0525
Loa Loa (eye worm) glutaminase 0.0556 0.2112 0.6417
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0012 0.0096
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0065 0.0504
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0192 0.0689 0.1321
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0127 0.0435 0.336
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0011 0.0014
Leishmania major basic transcription factor 3a, putative 0.0035 0.0075 0.0577
Trypanosoma brucei DNA polymerase kappa, putative 0.0203 0.073 0.5641
Loa Loa (eye worm) 6-phosphofructokinase 0.022 0.0796 0.2418
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0012 0.0096
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0146 0.0508 0.0621
Schistosoma mansoni ap endonuclease 0.006 0.017 0.0207
Loa Loa (eye worm) hypothetical protein 0.0054 0.0149 0.0454
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0021 0.002 0.0145
Plasmodium falciparum phd finger protein, putative 0.0059 0.0169 0.1297
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0149 0.0454
Schistosoma mansoni lamin 0.0054 0.0149 0.0181
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0221 0.0247
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0001 0.0002
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0277 0.1022 0.3102
Trichomonas vaginalis chromobox protein, putative 0.0141 0.0486 0.0933
Entamoeba histolytica hypothetical protein 0.0023 0.0026 0.0055
Echinococcus multilocularis lamin 0.0054 0.0149 0.0183
Onchocerca volvulus 0.0062 0.0178 0.0461
Trypanosoma cruzi phosphoinositide-specific phospholipase C, putative 0.0019 0.0009 0.0072
Mycobacterium leprae PROBABLE BIFUNCTIONAL PENICILLIN-BINDING PROTEIN 1A/1B PONA1 (MUREIN POLYMERASE) (PBP1): PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE 0.1349 0.5213 0.9243
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0018 0.0022
Loa Loa (eye worm) hypothetical protein 0.0073 0.0221 0.0672
Schistosoma mansoni hypothetical protein 0.0059 0.0169 0.0205
Brugia malayi Phosphoglycerate kinase 0.0347 0.1294 0.3928
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.003 0.0054 0.0406
Echinococcus multilocularis bloom syndrome protein 0.0044 0.0109 0.0134
Entamoeba histolytica hypothetical protein 0.0022 0.0022 0.0045
Brugia malayi jmjC domain containing protein 0.0195 0.0698 0.2117
Brugia malayi glutathione reductase 0.0048 0.0123 0.0371
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0028 0.0085
Leishmania major phosphoglycerate kinase C, glycosomal 0.0347 0.1294 1
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0017 0.0001 0.0002
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0018 0.0022
Schistosoma mansoni blooms syndrome DNA helicase 0.0029 0.005 0.0059
Onchocerca volvulus 0.0023 0.0026 0.0056
Schistosoma mansoni lipoxygenase 0.0084 0.0267 0.0325
Trichomonas vaginalis chromobox protein, putative 0.0141 0.0486 0.0933
Treponema pallidum penicillin-binding protein (pbp-3) 0.2458 0.9553 0.9553
Onchocerca volvulus 0.0976 0.3755 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.0418 0.051
Loa Loa (eye worm) transcriptional regulator 0.0017 0.0001 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0221 0.171
Echinococcus granulosus L aminoadipate semialdehyde 0.0085 0.027 0.033
Mycobacterium tuberculosis Possible penicillin-binding lipoprotein 0.0785 0.301 0.5336
Echinococcus granulosus jumonji domain containing protein 0.0083 0.026 0.0319
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0008 0.0009
Mycobacterium ulcerans glutaminase 0.0556 0.2112 0.2366
Mycobacterium ulcerans hypothetical protein 0.002 0.0016 0.0016
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0054 0.0406
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0059 0.0169 0.1295
Treponema pallidum hypothetical protein 0.0288 0.1064 0.1063
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0127 0.0435 0.336
Schistosoma mansoni rotamase 0.0067 0.02 0.0244
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0221 0.0424
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0018 0.005
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0052 0.014 0.1083
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0021 0.002 0.0041
Echinococcus multilocularis lamin dm0 0.0054 0.0149 0.0183
Brugia malayi Bloom's syndrome protein homolog 0.0044 0.0109 0.0329
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0075 0.0227
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0068 0.0525
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0004 0.0021
Schistosoma mansoni hypothetical protein 0.0018 0.0008 0.0008
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0059 0.0169 0.0167
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0277 0.1022 0.79
Mycobacterium ulcerans hypothetical protein 0.0038 0.0084 0.0093
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0023 0.0026 0.0031
Leishmania major trypanothione reductase 0.0048 0.0123 0.0954
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0068 0.0206
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0026 0.0195
Plasmodium vivax hypothetical protein, conserved 0.0017 0.0001 0.0001
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0026 0.0051
Onchocerca volvulus 0.0192 0.0689 0.1823
Leishmania major phosphoglycerate kinase B, cytosolic 0.0347 0.1294 1
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0021 0.002 0.0024
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0169 0.0324
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0084 0.0653
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0001 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0203 0.073 0.5641
Entamoeba histolytica hypothetical protein 0.0023 0.0026 0.0055
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0001 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0051
Brugia malayi follicle stimulating hormone receptor 0.0239 0.0871 0.2642
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0021 0.002 0.0024
Brugia malayi beta-lactamase family protein 0.0073 0.0221 0.0669
Trypanosoma brucei trypanothione reductase 0.0048 0.0123 0.0954
Echinococcus multilocularis RUN 0.002 0.0015 0.0019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0203 0.073 0.5641
Brugia malayi SET domain containing protein 0.0028 0.0044 0.013
Trypanosoma brucei small ubiquitin-related modifier 0.0063 0.0181 0.14
Brugia malayi nuclear hormone receptor 0.0021 0.0018 0.005
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0465 0.1756 0.3113
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0347 0.1294 0.2293
Schistosoma mansoni chromobox protein 0.0023 0.0026 0.0031
Schistosoma mansoni jumonji domain containing protein 0.0155 0.0541 0.0662
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.022 0.0796 0.0795
Giardia lamblia Sgs1 DNA helicase, putative 0.003 0.0054 0.0117
Trichomonas vaginalis Heterochromatin protein, putative 0.0023 0.0026 0.0051
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0011 0.0013
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0183 0.0653 0.0731
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0238 0.1835
Echinococcus granulosus ATP dependent DNA helicase Q5 0.003 0.0054 0.0066
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0163
Plasmodium vivax heterochromatin protein 1, putative 0.0023 0.0026 0.0195
Giardia lamblia DNA damage repair protein 0.0038 0.0084 0.0184
Giardia lamblia Hypothetical protein 0.0017 0.0001 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0075 0.0143
Loa Loa (eye worm) hypothetical protein 0.0123 0.0418 0.1269
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0277 0.1022 0.79
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0015 0.0019
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0075 0.0577
Brugia malayi Bromodomain containing protein 0.0059 0.0169 0.051
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0018 0.005
Brugia malayi M-phase phosphoprotein, mpp8 0.0023 0.0026 0.0077
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0001 0.001
Echinococcus multilocularis microtubule associated protein 2 0.2102 0.8161 1
Echinococcus granulosus lysine specific demethylase 5A 0.0072 0.0218 0.0267
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0075 0.016
Loa Loa (eye worm) beta-lactamase 0.0073 0.0221 0.0672
Echinococcus multilocularis GPCR, family 2 0.0018 0.0008 0.0009
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.003 0.0054 0.0066
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0023 0.0026 0.0195
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0047
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.0026 0.0031
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0016
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0017 0.0001 0.0011
Echinococcus multilocularis transcription factor Dp 1 0.0161 0.0565 0.0692
Schistosoma mansoni chromobox protein 0.0141 0.0486 0.0595
Schistosoma mansoni phosphoglycerate kinase 0.0347 0.1294 0.1584
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0018 0.0053
Toxoplasma gondii endonuclease IV APN 0.0077 0.0238 0.1835
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0123 0.0375
Schistosoma mansoni hypothetical protein 0.0031 0.0059 0.007
Mycobacterium ulcerans DNA polymerase IV 0.0203 0.073 0.0817
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0053
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0053
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0059 0.0169 0.0167
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0066 0.0194 0.1498
Brugia malayi F/Y-rich N-terminus family protein 0.0024 0.003 0.0088
Plasmodium vivax phosphoglycerate kinase, putative 0.0347 0.1294 1
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0127 0.0435 0.336
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0011 0.0013
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0085 0.027 0.0329
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0011 0.0014
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0039 0.0048
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0004 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0344 0.2658
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0008 0.0019
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0026 0.0051
Loa Loa (eye worm) doublecortin family protein 0.002 0.0015 0.0047
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0149 0.045
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.003 0.0223
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0008 0.0023
Treponema pallidum exodeoxyribonuclease (exoA) 0.006 0.017 0.0169
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0155 0.0297
Schistosoma mansoni glutaminase 0.0556 0.2112 0.2587
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0221 0.1702
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0038
Trypanosoma brucei chrX additional, unordered contigs 0.0038 0.0084 0.0653
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0203 0.073 0.14
Schistosoma mansoni hypothetical protein 0.0018 0.0008 0.0008
Toxoplasma gondii proteasome regulatory subunit 0.0021 0.002 0.0145
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0195 0.0698 0.0855
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0089 0.0286 0.2199
Mycobacterium tuberculosis Probable bifunctional penicillin-binding protein 1A/1B PonA1 (murein polymerase) (PBP1): penicillin-insensitive transglycosylase 0.0431 0.1623 0.2876
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0008 0.0009
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0347 0.1294 1
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0058 0.0163 0.1251
Schistosoma mansoni rab6-interacting 0.002 0.0015 0.0017
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0019 0.0012 0.0086
Trypanosoma cruzi DNA polymerase kappa, putative 0.0203 0.073 0.5641
Echinococcus granulosus pyruvate kinase 0.0034 0.0068 0.0083
Echinococcus multilocularis peregrin 0.0059 0.0169 0.0207
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0001 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0026 0.0051
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0018 0.0022
Trichomonas vaginalis chromobox protein, putative 0.0085 0.0268 0.0514
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0121 0.0409 0.0501
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.119 0.4591 0.8806
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0018 0.005
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0021 0.002 0.0145
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0401 0.3099
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0192 0.0689 0.1321
Plasmodium vivax glutathione reductase, putative 0.0048 0.0123 0.0946
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0018 0.005
Loa Loa (eye worm) transcriptional regulator 0.0017 0.0001 0.0004
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0039 0.0048
Brugia malayi Matrixin family protein 0.0018 0.0005 0.0012
Trichomonas vaginalis hypothetical protein 0.0023 0.0026 0.0051
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.002 0.0017 0.0119
Mycobacterium ulcerans phosphoglycerate kinase 0.0347 0.1294 0.1449
Echinococcus multilocularis chromatin regulatory protein sir2 0.0017 0.0001 0.0002
Schistosoma mansoni jumonji/arid domain-containing protein 0.0072 0.0218 0.0265
Mycobacterium leprae Probable penicillin-binding membrane protein PbpB 0.0672 0.2564 0.4532
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0018 0.0022
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0018 0.0022
Echinococcus granulosus pyruvate kinase 0.0017 0.0004 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0075 0.0143
Brugia malayi beta-lactamase family protein 0.0073 0.0221 0.0669
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.003 0.0054 0.0159
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0026 0.0051
Echinococcus granulosus dna polymerase eta 0.0173 0.0614 0.0753
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0023 0.0026 0.0032
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0192 0.0689 0.15
Onchocerca volvulus 0.0073 0.0221 0.0576
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0363 0.0642
Brugia malayi Hemopexin family protein 0.0025 0.0034 0.01
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0221 0.0365
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.006 0.017 0.03
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0068 0.013
Plasmodium falciparum DNA repair protein REV1, putative 0.0038 0.0084 0.0644
Brugia malayi hypothetical protein 0.002 0.0015 0.0043
Echinococcus granulosus ATP dependent DNA helicase Q1 0.003 0.0054 0.0066
Loa Loa (eye worm) heterochromatin protein 1 0.0141 0.0486 0.1478
Schistosoma mansoni hypothetical protein 0.0018 0.0008 0.0008
Brugia malayi phosphofructokinase 0.022 0.0796 0.2416
Echinococcus multilocularis chromobox protein 1 0.0141 0.0486 0.0596
Echinococcus granulosus lamin 0.0054 0.0149 0.0183
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.002 0.0017 0.0128
Onchocerca volvulus 0.0031 0.0059 0.0142
Trypanosoma cruzi DNA polymerase kappa, putative 0.0203 0.073 0.5641
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0018 0.0033
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.0011 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0401 0.3099
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0001 0.0003
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0023 0.0026 0.0077
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.119 0.4591 0.8806
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0001 0.001
Trypanosoma brucei SIR2-like protein 4, putative 0.0017 0.0001 0.0011
Brugia malayi Cell death protein 3 precursor 0.0031 0.0059 0.0174
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0058 0.0161 0.049
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0016 0.0026
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.0019 0.0009 0.0028
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0192 0.0689 0.1498
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0018 0.002
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0039 0.012
Trypanosoma brucei unspecified product 0.0084 0.0265 0.2051
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0051
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0068 0.0203
Echinococcus granulosus GPCR family 2 0.0018 0.0008 0.0009
Brugia malayi 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 0.0018 0.0005 0.0012
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0068 0.0206
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0018 0.002
Brugia malayi Matrixin family protein 0.0018 0.0005 0.0012
Entamoeba histolytica hypothetical protein 0.0023 0.0026 0.0055
Plasmodium vivax SET domain protein, putative 0.0123 0.0418 0.3222
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0067 0.02 0.0604
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0221 0.039
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.0063 0.0181 0.022
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.0098 0.0748
Giardia lamblia PHD finger protein 15 0.0059 0.0169 0.0368
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0047
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0075 0.0577
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.006 0.017 0.0209
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0018 0.0053
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0169 0.0324
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0221 0.0271
Loa Loa (eye worm) jmjC domain-containing protein 0.0072 0.0218 0.0662
Trypanosoma brucei DNA polymerase kappa, putative 0.0203 0.073 0.5641
Mycobacterium ulcerans penicillin-binding protein PbpA 0.1457 0.5639 0.6319
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0026 0.0051
Loa Loa (eye worm) sirtuin 4 0.0017 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0178
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0017 0.0001 0.0002
Loa Loa (eye worm) ATP-dependent DNA helicase 0.003 0.0054 0.0163
Brugia malayi hypothetical protein 0.0031 0.0059 0.0174
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0183 0.0653 0.1981
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0077 0.0238 0.0396
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0192 0.0689 0.1498
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0075 0.0143
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0059 0.0169 0.0167
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0053
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0018 0.0022
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0023 0.0026 0.0032
Mycobacterium leprae PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) [INCLUDES: PENICILLIN-INSEN 0.1079 0.4157 0.7365
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0011 0.0035
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0277 0.1022 0.1251
Leishmania major DNA polymerase kappa, putative 0.0142 0.0492 0.3802
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0019 0.0009 0.0025
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.002 0.0017 0.0128
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0017 0.0001 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0059 0.0168 0.1301
Mycobacterium ulcerans 6-phosphofructokinase 0.022 0.0796 0.0891
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0018 0.0053
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0023 0.0026 0.0032
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.003 0.0029
Echinococcus granulosus peregrin 0.0059 0.0169 0.0207
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.008
Mycobacterium ulcerans beta-lactamase 0.0073 0.0221 0.0247
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0015 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0051
Brugia malayi Flap endonuclease-1 0.0026 0.0039 0.0116
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.0012 0.0086
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0059 0.0169 0.0205
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0277 0.1022 0.2224
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0018 0.0053
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0018 0.002
Brugia malayi exodeoxyribonuclease III family protein 0.006 0.017 0.0514
Echinococcus granulosus flap endonuclease 1 0.0026 0.0039 0.0048
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0221 0.0271
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.006 0.017 0.1317
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.006 0.017 0.0169
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.008
Echinococcus multilocularis expressed protein 0.0067 0.02 0.0245
Brugia malayi CHD4 protein 0.0023 0.0026 0.0077
Loa Loa (eye worm) hypothetical protein 0.0026 0.0039 0.0119
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0068 0.0167
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0221 0.171
Brugia malayi Matrixin family protein 0.0018 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0025 0.0035 0.0107
Leishmania major phosphoinositide-specific phospholipase C, putative 0.0018 0.0005 0.004
Loa Loa (eye worm) hypothetical protein 0.0073 0.0221 0.0672
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0018 0.0005 0.0012
Echinococcus multilocularis chromobox protein 1 0.0141 0.0486 0.0596
Plasmodium vivax 6-phosphofructokinase, putative 0.0059 0.0169 0.1295
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.0411 0.0726
Onchocerca volvulus 0.0146 0.0508 0.134
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0068 0.0075
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0001 0.0003
Mycobacterium ulcerans hypothetical protein 0.0073 0.0221 0.0247
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0068 0.0118
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0221 0.039
Trypanosoma cruzi DNA polymerase eta, putative 0.0173 0.0614 0.4749
Schistosoma mansoni pyruvate kinase 0.0034 0.0068 0.0082
Entamoeba histolytica phosphofructokinase, putative 0.022 0.0796 0.1732
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.006 0.017 0.019
Leishmania major DNA polymerase eta, putative 0.0089 0.0286 0.2207
Plasmodium vivax hypothetical protein, conserved 0.0059 0.0169 0.1297
Echinococcus granulosus Solute carrier family 22 5 0.1047 0.4031 0.4939
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0011 0.0013
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0026 0.0051
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0052 0.014 0.1074
Onchocerca volvulus 0.0023 0.0026 0.0056
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0192 0.0689 0.2092
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0192 0.0689 0.0771
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0026 0.0051
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0059 0.0169 0.0367
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0192 0.0689 0.1321
Brugia malayi Heterochromatin protein 1 0.0141 0.0486 0.1474
Loa Loa (eye worm) hypothetical protein 0.0073 0.0221 0.0672
Schistosoma mansoni lipoxygenase 0.0121 0.0409 0.05
Brugia malayi ecdysteroid receptor 0.0021 0.0018 0.005
Schistosoma mansoni lamin 0.0054 0.0149 0.0181
Mycobacterium ulcerans serine/threonine-protein kinase B PknB 0.0161 0.0566 0.0633
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0028
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0059 0.0169 0.0365
Entamoeba histolytica recQ family helicase, putative 0.0033 0.0065 0.0139
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.0411 0.0726
Brugia malayi jmjC domain containing protein 0.0072 0.0218 0.0658
Loa Loa (eye worm) PHD-finger family protein 0.0059 0.0169 0.0513
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0052 0.014 0.1083
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.006 0.017 0.0371
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0344 0.2658
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0169 0.1297
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0018 0.0005 0.0005
Onchocerca volvulus 0.0019 0.0009 0.0011
Plasmodium falciparum phosphoinositide-specific phospholipase C 0.0018 0.0005 0.003
Plasmodium falciparum small ubiquitin-related modifier 0.0063 0.0181 0.1391
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0015 0.011
Schistosoma mansoni hypothetical protein 0.0018 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0023 0.0026 0.0031
Loa Loa (eye worm) hypothetical protein 0.0034 0.0068 0.0206
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0221 0.039
Trichomonas vaginalis DNA helicase recq1, putative 0.0044 0.0109 0.021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.0067
Mycobacterium ulcerans hydrolase 0.0021 0.002 0.0021
Brugia malayi hypothetical protein 0.002 0.0015 0.0043
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.0411 0.0726
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0016 0.0016
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0068 0.0516
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0221 0.0424
Echinococcus granulosus intermediate filament protein 0.0054 0.0149 0.0183
Echinococcus multilocularis neuropeptide s receptor 0.047 0.1774 0.2174
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0026 0.0051
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.006 0.017 0.1317
Trichomonas vaginalis ap endonuclease, putative 0.006 0.017 0.0327
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0016
Toxoplasma gondii histone deacetylase SIR2 0.0052 0.014 0.1074
Mycobacterium tuberculosis Conserved protein 0.0073 0.0221 0.039
Echinococcus granulosus geminin 0.0342 0.1274 0.1561
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0018 0.0022
Chlamydia trachomatis endonuclease IV 0.0077 0.0238 0.0237
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0122 0.0413 0.0505
Mycobacterium ulcerans endonuclease IV 0.0077 0.0238 0.0266
Echinococcus multilocularis 6 phosphofructokinase 0.022 0.0796 0.0975
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0018 0.002
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0277 0.1022 0.1252
Mycobacterium leprae POSSIBLE PENICILLIN-BINDING LIPOPROTEIN 0.0785 0.301 0.5324
Chlamydia trachomatis pyruvate kinase 0.0034 0.0068 0.0067
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0001 0.001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.0418 0.051
Entamoeba histolytica phosphofructokinase, putative 0.022 0.0796 0.1732
Brugia malayi hypothetical protein 0.0023 0.0026 0.0077
Chlamydia trachomatis phosphoglycerate kinase 0.0347 0.1294 0.1293
Echinococcus granulosus Chromo domain 0.0023 0.0026 0.0032
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0001 0.001
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0052 0.014 0.1083
Loa Loa (eye worm) hypothetical protein 0.0085 0.027 0.0819
Schistosoma mansoni hypothetical protein 0.0025 0.0034 0.004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0018 0.005
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.006 0.017 0.0209
Loa Loa (eye worm) phosphofructokinase 0.022 0.0796 0.2418
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0858 0.3292 1
Echinococcus multilocularis neuropeptide receptor A26 0.047 0.1774 0.2174

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 3 nM Inhibition of recombinant p56 Lck tyrosine kinase expressed in insect cells ChEMBL. 15317463
IC50 (functional) = 490 nM Inhibition of Human PBL (T cell) proliferation ChEMBL. 15317463

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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