Detailed information for compound 511688

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 461.387 | Formula: C20H14Cl2N4OS2
  • H donors: 2 H acceptors: 3 LogP: 6.38 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1ccccc1)Nc1sc(c(n1)C)c1csc(n1)Nc1cccc(c1Cl)Cl
  • InChi: 1S/C20H14Cl2N4OS2/c1-11-17(29-20(23-11)26-18(27)12-6-3-2-4-7-12)15-10-28-19(25-15)24-14-9-5-8-13(21)16(14)22/h2-10H,1H3,(H,24,25)(H,23,26,27)
  • InChiKey: JJRFLKWBRKXEDY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0026 0.0039 0.0112
Echinococcus granulosus microtubule associated protein 2 0.2186 0.879 1
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0074 0.0212
Mycobacterium leprae PROBABLE HYDROLASE 0.0022 0.0023 0.0009
Mycobacterium ulcerans penicillin-binding membrane protein PbpB 0.223 0.8967 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.006 0.0175 0.1248
Brugia malayi CHD4 protein 0.0024 0.003 0.0085
Giardia lamblia Transcriptional regulator, Sir2 family 0.0054 0.0152 0.0311
Brugia malayi Pre-SET motif family protein 0.0882 0.3505 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0028 0.0047 0.0134
Plasmodium vivax 6-phosphofructokinase, putative 0.0062 0.0182 0.1301
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0015 0.0105
Entamoeba histolytica phosphofructokinase, putative 0.0228 0.0856 0.1756
Plasmodium vivax basic transcription factor 3b, putative 0.0071 0.0219 0.1565
Mycobacterium tuberculosis Possible penicillin-binding protein 0.048 0.1879 0.3346
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0028 0.0047 0.0134
Mycobacterium tuberculosis Probable bifunctional penicillin-binding protein 1A/1B PonA1 (murein polymerase) (PBP1): penicillin-insensitive transglycosylase 0.0422 0.1643 0.2926
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0275 0.1049 0.2991
Giardia lamblia Pyruvate kinase 0.0018 0.0005 0.0009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1217 0.4863 0.9223
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0265 0.0501
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0362 0.14 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0028 0.0047 0.0134
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0072 0.0511
Trypanosoma cruzi transcription factor btf3, putative 0.0071 0.0219 0.1565
Mycobacterium tuberculosis Probable lipase LipD 0.0075 0.0237 0.0422
Loa Loa (eye worm) matrixin family protein 0.0044 0.0112 0.0321
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0062 0.0182 0.018
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0018 0.0007 0.0019
Echinococcus granulosus ecdysone induced protein 78C 0.0028 0.0047 0.0054
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0035
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.003 0.0054
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0139 0.0496 0.0883
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1217 0.4863 1
Chlamydia trachomatis transglycolase/transpeptidase 0.1148 0.4583 0.4582
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0362 0.14 1
Mycobacterium ulcerans hydrolase 0.0022 0.0023 0.0024
Onchocerca volvulus 0.0026 0.0038 0.0078
Brugia malayi jmjC domain containing protein 0.002 0.0014 0.0039
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.0018 0.0028
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0062 0.0182 0.1301
Brugia malayi Matrixin family protein 0.0018 0.0007 0.002
Echinococcus multilocularis pyruvate kinase 0.0035 0.0074 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.003 0.0054
Schistosoma mansoni hypothetical protein 0.052 0.2041 0.2322
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.0047 0.0134
Loa Loa (eye worm) hypothetical protein 0.0035 0.0074 0.0212
Schistosoma mansoni lamin 0.0057 0.0162 0.0185
Brugia malayi Heterochromatin protein 1 0.0146 0.0526 0.1501
Trypanosoma brucei DNA polymerase kappa, putative 0.0208 0.0777 0.5549
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0034 0.0038
Mycobacterium leprae PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC 0.03 0.115 0.2022
Toxoplasma gondii PHD-finger domain-containing protein 0.0062 0.0184 0.1314
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0002 0.0014
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0003 0.0003
Mycobacterium ulcerans epimerase 0.0021 0.0018 0.0018
Treponema pallidum penicillin-binding protein (pbp-2) 0.1318 0.5272 0.5271
Loa Loa (eye worm) hypothetical protein 0.0362 0.14 0.3993
Leishmania major hypothetical protein, conserved 0.0075 0.0237 0.1695
Echinococcus granulosus lysine specific demethylase 5A 0.0075 0.0237 0.0269
Trichomonas vaginalis phosphofructokinase, putative 0.0228 0.0856 0.1622
Echinococcus granulosus Chromo domain 0.0024 0.003 0.0034
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0594 0.2341 0.2609
Mycobacterium ulcerans phosphoglycerate kinase 0.0362 0.14 0.1559
Echinococcus multilocularis dna polymerase eta 0.018 0.066 0.0751
Echinococcus multilocularis dna polymerase kappa 0.0208 0.0777 0.0884
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0362 0.14 0.2468
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.003 0.0054
Echinococcus granulosus 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 0.0019 0.0011 0.0013
Mycobacterium tuberculosis Conserved protein 0.0075 0.0237 0.0422
Loa Loa (eye worm) transcriptional regulator 0.0017 0.0003 0.0008
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0179 0.0658 0.0748
Toxoplasma gondii pyruvate kinase PyK1 0.0035 0.0074 0.0532
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0201 0.0747 0.1415
Plasmodium falciparum phosphoinositide-specific phospholipase C 0.0018 0.0007 0.0049
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0126 0.0443 0.0504
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0028 0.0047 0.0054
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0002 0.0014
Echinococcus multilocularis chromobox protein 2 0.0024 0.003 0.0034
Trichomonas vaginalis chromobox protein, putative 0.0024 0.003 0.0054
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0124
Echinococcus granulosus 6 phosphofructokinase 0.0228 0.0856 0.0974
Echinococcus granulosus beta LACTamase domain containing family member 0.0075 0.0237 0.027
Schistosoma mansoni caspase-7 (C14 family) 0.0033 0.0064 0.0073
Entamoeba histolytica hypothetical protein 0.0024 0.003 0.0056
Schistosoma mansoni hypothetical protein 0.0033 0.0064 0.0073
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0021 0.0019 0.0136
Echinococcus granulosus FTZ F1 alpha 0.0028 0.0047 0.0054
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0445 0.0506
Echinococcus multilocularis Small ubiquitin modifier 2 0.0065 0.0197 0.0224
Echinococcus granulosus chromobox protein 2 0.0024 0.003 0.0034
Leishmania major proteasome regulatory non-ATP-ase subunit 11, putative,19S proteasome regulatory subunit, Metallo- peptidase, Clan MP, Family M6 0.0017 0.0001 0.0009
Brugia malayi Flap endonuclease-1 0.0027 0.0043 0.0122
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0182 0.0343
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0362 0.14 0.2653
Mycobacterium ulcerans hypothetical protein 0.0039 0.0091 0.0099
Plasmodium vivax hypothetical protein, conserved 0.0017 0.0003 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.1318 0.5272 1
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0015 0.0105
Schistosoma mansoni thyroid hormone receptor 0.0028 0.0047 0.0054
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0017 0.0003 0.0003
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0027 0.0048
Trypanosoma brucei unspecified product 0.0188 0.0694 0.4958
Trypanosoma brucei DNA damage repair protein, putative 0.0039 0.0091 0.065
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0039
Echinococcus multilocularis neuropeptide s receptor 0.0489 0.1915 0.2179
Trichomonas vaginalis DNA polymerase eta, putative 0.0208 0.0777 0.1471
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0018 0.0018
Trypanosoma brucei phosphoglycerate kinase 0.0362 0.14 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0237 0.027
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0021 0.0019 0.0136
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0067 0.0203 0.0231
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0032
Brugia malayi Bromodomain containing protein 0.0062 0.0184 0.0525
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0022 0.0023 0.0065
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0003 0.0003
Wolbachia endosymbiont of Brugia malayi cell division protein FtsI 0.2485 1 1
Entamoeba histolytica hypothetical protein 0.0024 0.003 0.0056
Entamoeba histolytica ubiquitin like protein 0.0065 0.0197 0.04
Brugia malayi PHD-finger family protein 0.0062 0.0184 0.0525
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0134
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.003 0.0054
Echinococcus multilocularis lamin dm0 0.0057 0.0162 0.0185
Entamoeba histolytica transcription factor BTF3, putative 0.0071 0.0219 0.0445
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.0047 0.0134
Schistosoma mansoni 6-phosphofructokinase 0.0228 0.0856 0.0974
Loa Loa (eye worm) hypothetical protein 0.0056 0.0158 0.0451
Loa Loa (eye worm) sirtuin 4 0.0017 0.0003 0.0008
Brugia malayi hypothetical protein 0.0033 0.0064 0.0184
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0002 0.0002
Brugia malayi transcriptional regulator, Sir2 family protein 0.0017 0.0003 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0445 0.0506
Mycobacterium leprae Probable lipase LipE 0.0075 0.0237 0.0391
Leishmania major phosphatidylinositol-specific phospholipase-like protein 0.0018 0.0007 0.0049
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0047 0.0054
Trypanosoma brucei DNA polymerase IV, putative 0.0208 0.0777 0.5549
Schistosoma mansoni ap endonuclease 0.006 0.0175 0.0199
Echinococcus granulosus chromatin regulatory protein sir2 0.0017 0.0003 0.0003
Trypanosoma brucei pyruvate kinase 1, putative 0.0035 0.0074 0.0532
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0126 0.0445 0.0506
Echinococcus multilocularis jumonji domain containing protein 0.0086 0.0282 0.0321
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0146 0.0526 0.0936
Plasmodium vivax NAD-dependent deacetylase, putative 0.0054 0.0152 0.1089
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0002 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.003 0.0054
Giardia lamblia DNA damage repair protein 0.0039 0.0091 0.0185
Trypanosoma cruzi DNA polymerase eta, putative 0.0093 0.0308 0.22
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0024 0.003 0.0034
Echinococcus granulosus Solute carrier family 22 5 0.1081 0.4312 0.4906
Brugia malayi Steroid receptor seven-up type 2 0.0028 0.0047 0.0134
Toxoplasma gondii thioredoxin reductase 0.0049 0.0133 0.0948
Mycobacterium tuberculosis Conserved hypothetical protein 0.0126 0.0443 0.0789
Toxoplasma gondii histone lysine demethylase JMJD6a 0.002 0.0014 0.0098
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0042
Schistosoma mansoni transcription factor btf3 0.0071 0.0219 0.0249
Trypanosoma cruzi phosphoinositide-specific phospholipase C, putative 0.0019 0.0011 0.008
Schistosoma mansoni 6-phosphofructokinase 0.0228 0.0856 0.0974
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0594 0.2341 0.4169
Plasmodium vivax phosphoglycerate kinase, putative 0.0362 0.14 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0121 0.0425 0.3034
Loa Loa (eye worm) CHromoDomain protein family member 0.0024 0.003 0.0085
Brugia malayi Variant SH3 domain containing protein 0.0134 0.0475 0.1355
Trypanosoma brucei phosphoglycerate kinase 0.0362 0.14 1
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.003 0.0054
Schistosoma mansoni rab6-interacting 0.002 0.0012 0.0014
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1217 0.4863 1
Leishmania major sir2-family protein-like protein 0.0017 0.0003 0.0019
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0028 0.0047 0.0054
Giardia lamblia Phosphoglycerate kinase 0.0362 0.14 0.2876
Trypanosoma cruzi DNA polymerase eta, putative 0.018 0.066 0.4715
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0017 0.0001 0.0009
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0054 0.0152 0.0308
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0167 0.0609 0.1737
Trypanosoma brucei phosphoglycerate kinase 0.0133 0.0471 0.3366
Mycobacterium tuberculosis Probable penicillin-binding membrane protein PbpB 0.0651 0.257 0.4576
Trypanosoma brucei DNA polymerase kappa, putative 0.0208 0.0777 0.5549
Loa Loa (eye worm) hypothetical protein 0.0075 0.0237 0.0677
Schistosoma mansoni chromatin regulatory protein sir2 0.0017 0.0003 0.0003
Echinococcus multilocularis RUN 0.002 0.0012 0.0014
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0113 0.0389 0.0693
Treponema pallidum penicillin-binding protein (pbp-1) 0.2485 1 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0028 0.0047 0.0054
Onchocerca volvulus 0.0057 0.0162 0.0389
Brugia malayi photoreceptor-specific nuclear receptor 0.0028 0.0047 0.0134
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0002 0.0014
Toxoplasma gondii 6-phosphofructokinase 0.0062 0.0182 0.1301
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0002 0.0014
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0017 0.0003 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.003 0.0054
Mycobacterium ulcerans bifunctional penicillin-binding protein 1A/1B PonA1 0.1318 0.5272 0.5879
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0126 0.0443 0.0504
Onchocerca volvulus Matrix metalloproteinase homolog 0.0041 0.0098 0.0227
Echinococcus multilocularis musashi 0.0057 0.0162 0.0185
Leishmania major phosphoinositide-specific phospholipase C, putative 0.0018 0.0007 0.0049
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0027 0.0192
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0113 0.0389 0.0693
Brugia malayi Bloom's syndrome protein homolog 0.0046 0.0119 0.034
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.006 0.0174 0.1242
Plasmodium vivax heterochromatin protein 1, putative 0.0024 0.003 0.0212
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0021 0.0019 0.0136
Echinococcus multilocularis pyruvate kinase 0.0018 0.0005 0.0006
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0014 0.0039
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0002 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.0228 0.0856 0.1622
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0002 0.0014
Brugia malayi M-phase phosphoprotein, mpp8 0.0024 0.003 0.0085
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0237 0.0448
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0031 0.0059 0.0067
Plasmodium falciparum pyruvate kinase 0.0035 0.0074 0.0532
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0091 0.065
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0019 0.0011 0.0032
Plasmodium vivax pyruvate kinase, putative 0.0035 0.0074 0.0532
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0002 0.0001
Plasmodium vivax hypothetical protein, conserved 0.0024 0.003 0.0212
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.003 0.0034
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0082 0.0265 0.0647
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0014 0.0098
Brugia malayi transcriptional regulator, Sir2 family protein 0.0017 0.0003 0.0008
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0091 0.065
Brugia malayi Matrixin family protein 0.0044 0.0112 0.0321
Brugia malayi jmjC domain containing protein 0.002 0.0014 0.0039
Leishmania major small ubiquitin protein, putative 0.0065 0.0197 0.1408
Trichomonas vaginalis rotamase, putative 0.0069 0.021 0.0397
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0268 0.0764
Trichomonas vaginalis chromobox protein, putative 0.0024 0.003 0.0054
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0134
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0014 0.0016
Mycobacterium ulcerans bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein 0.03 0.115 0.128
Plasmodium vivax nicotinate-nucleotide adenylyltransferase, putative 0.03 0.115 0.8216
Echinococcus granulosus pyruvate kinase 0.0035 0.0074 0.0085
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0014 0.0039
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0062 0.0184 0.0209
Brugia malayi nuclear receptor NHR-88 0.0028 0.0047 0.0134
Echinococcus granulosus RUN 0.002 0.0012 0.0014
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.0047 0.0134
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.0065 0.0197 0.0224
Leishmania major phosphoglycerate kinase C, glycosomal 0.0362 0.14 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0059 0.0169
Toxoplasma gondii phosphoinositide phospholipase PIPLC 0.0019 0.0011 0.008
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0031 0.0059 0.0422
Brugia malayi jmjC domain containing protein 0.002 0.0014 0.0039
Trypanosoma cruzi DNA damage repair protein, putative 0.0039 0.0091 0.065
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0059 0.0169
Mycobacterium ulcerans penicillin-binding protein PbpA 0.1403 0.5616 0.6262
Onchocerca volvulus 0.0075 0.0237 0.0577
Onchocerca volvulus 0.0023 0.0025 0.0045
Plasmodium falciparum basic transcription factor 3b, putative 0.0071 0.0219 0.1565
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0069 0.021 0.1503
Brugia malayi Pre-SET motif family protein 0.0126 0.0445 0.127
Echinococcus granulosus pyruvate kinase 0.0018 0.0005 0.0006
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0074 0.0169
Echinococcus multilocularis pyruvate kinase 0.0018 0.0005 0.0006
Echinococcus granulosus pyruvate kinase 0.0035 0.0074 0.0085
Schistosoma mansoni phospholipase C beta 0.0018 0.0007 0.0008
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0201 0.0747 0.1531
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0047 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0028 0.0047 0.0134
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0002 0.0014
Trichomonas vaginalis DNA helicase recq1, putative 0.0046 0.0119 0.0224
Mycobacterium ulcerans pyruvate kinase 0.0035 0.0074 0.0081
Trypanosoma cruzi DNA polymerase kappa, putative 0.0208 0.0777 0.5549
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0021 0.0019 0.0017
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.006 0.0175 0.0357
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0201 0.0747 0.1534
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0024 0.003 0.0034
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0179 0.0658 0.0731
Trypanosoma brucei small ubiquitin-related modifier 0.0065 0.0197 0.1408
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0028 0.0047 0.0054
Mycobacterium tuberculosis Conserved protein 0.0075 0.0237 0.0422
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0043 0.0122
Echinococcus granulosus pyruvate kinase 0.0018 0.0005 0.0006
Loa Loa (eye worm) transcriptional regulator 0.0017 0.0003 0.0008
Schistosoma mansoni lipoxygenase 0.0117 0.0408 0.0464
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.003 0.0054
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0054 0.0152 0.0287
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0201 0.0747 0.1415
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0125 0.044 0.0783
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0021 0.0019 0.0136
Brugia malayi Hemopexin family protein 0.0026 0.0038 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.003 0.0054
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1217 0.4863 0.9223
Loa Loa (eye worm) doublecortin family protein 0.002 0.0012 0.0035
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.006 0.0175 0.0173
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0362 0.14 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.006 0.0175 0.0311
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0074 0.0212
Trypanosoma cruzi DNA polymerase kappa, putative 0.0208 0.0777 0.5549
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0208 0.0777 0.1471
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0032
Trypanosoma brucei DNA damage repair protein, putative 0.0039 0.0091 0.065
Toxoplasma gondii ABC1 family protein 0.0075 0.0237 0.1695
Echinococcus granulosus neuropeptide receptor A26 0.0489 0.1915 0.2179
Loa Loa (eye worm) hypothetical protein 0.0024 0.0032 0.009
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0093 0.0308 0.22
Loa Loa (eye worm) SMO-1 protein 0.0065 0.0197 0.0562
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0002 0.0014
Schistosoma mansoni ap endonuclease 0.006 0.0175 0.0199
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0028 0.0047 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0028 0.0047 0.0134
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0015 0.0027
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0012 0.0014
Echinococcus granulosus transcription factor btf3 0.0071 0.0219 0.0249
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0362 0.14 0.1398
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0002 0.0014
Mycobacterium ulcerans DNA polymerase IV 0.0208 0.0777 0.0864
Echinococcus multilocularis PHD finger protein rhinoceros 0.0062 0.0184 0.0209
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0022 0.0023 0.0066
Entamoeba histolytica phosphoglycerate kinase, putative 0.0362 0.14 0.2874
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0882 0.3505 1
Loa Loa (eye worm) phosphofructokinase 0.0228 0.0856 0.2443
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.003 0.0054
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0002 0.0014
Echinococcus granulosus intermediate filament protein 0.0057 0.0162 0.0185
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0085
Entamoeba histolytica phosphofructokinase, putative 0.0228 0.0856 0.1756
Plasmodium vivax SET domain protein, putative 0.0126 0.0445 0.318
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0017 0.0003 0.0019
Echinococcus multilocularis pyruvate kinase 0.0035 0.0074 0.0085
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0275 0.1049 0.1193
Brugia malayi Ubiquitin-like protein SMT3 0.0065 0.0197 0.0562
Mycobacterium ulcerans endonuclease IV 0.008 0.0258 0.0286
Echinococcus multilocularis phosphoglycerate kinase 1 0.0362 0.14 0.1592
Trypanosoma brucei SIR2-like protein 4, putative 0.0017 0.0003 0.0019
Brugia malayi polk-prov protein 0.0121 0.0425 0.1212
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0175 0.0329
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0237 0.0448
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.002 0.0015 0.0105
Toxoplasma gondii proteasome regulatory subunit 0.0022 0.0023 0.0163
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0052
Loa Loa (eye worm) matrix metalloproteinase 0.0018 0.0007 0.002
Echinococcus multilocularis pyruvate kinase 0.0028 0.0045 0.0051
Echinococcus multilocularis transcription factor btf3 0.0071 0.0219 0.0249
Brugia malayi 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 0.0018 0.0007 0.0019
Brugia malayi Matrixin family protein 0.0018 0.0007 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0107 0.0367 0.2625
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.003 0.0054
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0062 0.0184 0.0346
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0125 0.044 0.0753
Schistosoma mansoni chromobox protein 0.0146 0.0526 0.0598
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0237 0.0448
Echinococcus granulosus lamin dm0 0.0057 0.0162 0.0185
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0062 0.0182 0.0343
Echinococcus granulosus caspase 2 0.0033 0.0064 0.0073
Echinococcus granulosus PHD finger protein rhinoceros 0.0062 0.0184 0.0209
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0043 0.0082
Leishmania major DNA polymerase eta, putative 0.0093 0.0308 0.22
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0179 0.0658 0.1876
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0075 0.0237 0.0263
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0074 0.0139
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0017 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0062 0.0184 0.0209
Loa Loa (eye worm) beta-lactamase 0.0075 0.0237 0.0677
Brugia malayi Cell death protein 3 precursor 0.0033 0.0064 0.0184
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0237 0.1695
Schistosoma mansoni retinoic acid receptor RXR 0.0028 0.0047 0.0054
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0085
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0027 0.0028
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0134
Schistosoma mansoni steroid hormone receptor ad4bp 0.0028 0.0047 0.0054
Schistosoma mansoni hypothetical protein 0.0024 0.003 0.0034
Schistosoma mansoni jumonji/arid domain-containing protein 0.0075 0.0237 0.0269
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0062 0.0182 0.018
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0028 0.0047 0.0134
Schistosoma mansoni protein phosphatase 2C 0.002 0.0014 0.0016
Leishmania major DNA polymerase kappa, putative 0.0146 0.0526 0.3756
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0275 0.1049 0.1193
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0062 0.0182 0.0372
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0028 0.0047 0.0134
Onchocerca volvulus Bile acid receptor homolog 0.0028 0.0047 0.0101
Entamoeba histolytica hypothetical protein 0.0023 0.0025 0.0046
Brugia malayi NAD-dependent deacetylase SIRT1 0.0017 0.0003 0.0008
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0062 0.0182 0.1301
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0074 0.0532
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.008 0.0258 0.0429
Echinococcus multilocularis caspase 2 0.0033 0.0064 0.0073
Trypanosoma brucei DNA polymerase eta, putative 0.018 0.066 0.4715
Schistosoma mansoni chromatin regulatory protein sir2 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Probable bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 (murein polymerase) [includes: penicillin-insen 0.1062 0.4235 0.7542
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0025 0.0045
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0201 0.0747 0.1415
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0133 0.0471 0.3366
Echinococcus granulosus apoptotic protease activating factor 1 0.0033 0.0064 0.0073
Loa Loa (eye worm) glutaminase 0.056 0.2201 0.628
Loa Loa (eye worm) 6-phosphofructokinase 0.0228 0.0856 0.2443
Schistosoma mansoni hypothetical protein 0.002 0.0012 0.0014
Plasmodium falciparum phd finger protein, putative 0.0062 0.0184 0.1314
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.003 0.0034
Trichomonas vaginalis hypothetical protein 0.0024 0.003 0.0054
Mycobacterium tuberculosis Probable dehydrogenase 0.0113 0.0389 0.0693
Trypanosoma brucei DNA polymerase kappa, putative 0.0208 0.0777 0.5549
Trypanosoma brucei DNA polymerase kappa, putative 0.0208 0.0777 0.5549
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0054 0.0152 0.1089
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0113 0.0389 0.0693
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0126 0.0445 0.0506
Onchocerca volvulus 0.0057 0.0162 0.0389
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0028 0.0045 0.032
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0237 0.027
Leishmania major ATP-dependent phosphofructokinase 0.0228 0.0856 0.6117
Mycobacterium ulcerans lipase LipD 0.0075 0.0237 0.0263
Mycobacterium tuberculosis Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic 0.03 0.115 0.2048
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0594 0.2341 0.415
Plasmodium vivax hypothetical protein, conserved 0.0024 0.003 0.0212
Loa Loa (eye worm) steroid hormone receptor 0.0028 0.0047 0.0134
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0021 0.0019 0.0136
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.006 0.0175 0.1248
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0012 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0208 0.0777 0.5549
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0002 0.0006
Plasmodium falciparum thioredoxin reductase 0.0049 0.0133 0.0948
Loa Loa (eye worm) RecQ helicase 0.0046 0.0119 0.034
Plasmodium vivax JmjC domain containing protein 0.002 0.0014 0.0098
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0179 0.0658 0.1171
Entamoeba histolytica deoxycytidyl transferase, putative 0.0126 0.0443 0.0906
Echinococcus granulosus lysine specific demethylase 6a 0.002 0.0014 0.0016
Brugia malayi intermediate filament protein 0.0057 0.0162 0.0463
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.003 0.0056
Onchocerca volvulus 0.0033 0.0064 0.0144
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0162 0.0463
Echinococcus granulosus dna polymerase kappa 0.0208 0.0777 0.0884
Brugia malayi Phosphoglycerate kinase 0.0362 0.14 0.3993
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0275 0.1049 0.7492
Echinococcus granulosus Chromobox protein 3 0.0024 0.003 0.0034
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0134 0.0475 0.1355
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0126 0.0443 0.0504
Loa Loa (eye worm) hypothetical protein 0.0075 0.0237 0.0677
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0122 0.0426 0.0485
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0003 0.0003
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0002 0.0001
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0022 0.0023 0.0041
Schistosoma mansoni DNA polymerase eta 0.018 0.066 0.0751
Entamoeba histolytica hypothetical protein 0.0071 0.0219 0.0445
Echinococcus granulosus lamin 0.0057 0.0162 0.0185
Schistosoma mansoni DNA polymerase IV / kappa 0.0039 0.0091 0.0104
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0175 0.1248
Schistosoma mansoni chromobox protein 0.0146 0.0526 0.0598
Mycobacterium ulcerans NAD-dependent deacetylase 0.0054 0.0152 0.0168
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0179 0.0658 0.4699
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0275 0.1049 0.1193
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0085
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0002 0.0003
Loa Loa (eye worm) transcriptional regulator 0.0017 0.0003 0.0008
Echinococcus granulosus Small ubiquitin modifier 2 0.0065 0.0197 0.0224
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0134
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0237 0.0448
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0002 0.0014
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.007 0.0217 0.0619
Leishmania major trypanothione reductase 0.0049 0.0133 0.0948
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.006 0.0175 0.0199
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0022 0.0023 0.0163
Plasmodium falciparum glutathione reductase 0.0049 0.0133 0.0948
Toxoplasma gondii endonuclease IV APN 0.008 0.0258 0.1846
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0027 0.0028
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0017 0.0003 0.0019
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0002 0.0014
Trichomonas vaginalis chromobox protein, putative 0.0024 0.003 0.0054
Brugia malayi AF-10 protein 0.002 0.0015 0.0042
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0039 0.0091 0.065
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0445 0.0506
Leishmania major pyruvate kinase 0.0035 0.0074 0.0532
Mycobacterium leprae Probable NAD-dependent deacetylase NpdA (Regulatory protein SIR2 homolog) 0.0037 0.0082 0.0114
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0237 0.0448
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0002 0.0014
Echinococcus multilocularis microtubule associated protein 2 0.2186 0.879 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0043 0.0049
Brugia malayi SET domain containing protein 0.0029 0.0049 0.0139
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0017 0.0003 0.0003
Echinococcus multilocularis transcription factor Dp 1 0.0159 0.0579 0.0658
Echinococcus granulosus neuropeptide s receptor 0.0489 0.1915 0.2179
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.003 0.0054
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.007 0.0217 0.0619
Echinococcus multilocularis lysine specific demethylase 6a 0.002 0.0014 0.0016
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0043 0.0085
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0056 0.0159
Brugia malayi follicle stimulating hormone receptor 0.0249 0.0941 0.2684
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0054 0.0152 0.1089
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0075 0.0237 0.0677
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0027 0.0192
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0002 0.0014
Toxoplasma gondii histone deacetylase SIR2 0.0054 0.0152 0.1089
Mycobacterium leprae Probable pyruvate kinase PykA 0.0035 0.0074 0.01
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0362 0.14 0.2492
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0022 0.0023 0.0026
Onchocerca volvulus 0.0201 0.0747 0.1854
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0043 0.0049
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0027 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0168 0.0317
Leishmania major DNA damage repair protein, putative 0.0039 0.0091 0.065
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0182 0.0343
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.002
Leishmania major hypothetical protein, conserved 0.0062 0.0184 0.1312
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0169
Schistosoma mansoni jumonji/arid domain-containing protein 0.0075 0.0237 0.0269
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.003 0.0054
Trypanosoma brucei transcription factor BTF3, putative 0.0071 0.0219 0.1565
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0133 0.0471 0.3366
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0237 0.1695
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0003 0.0003
Schistosoma mansoni terminal deoxycytidyl transferase 0.0126 0.0443 0.0504
Mycobacterium ulcerans glutaminase 0.056 0.2201 0.2453
Onchocerca volvulus 0.0083 0.0268 0.0654
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0022 0.0023 0.0065
Schistosoma mansoni chromatin regulatory protein sir2 0.0017 0.0003 0.0003
Plasmodium falciparum phosphoglycerate kinase 0.0362 0.14 1
Onchocerca volvulus 0.1004 0.3999 1
Treponema pallidum penicillin-binding protein (pbp-3) 0.2396 0.9641 0.9641
Trichomonas vaginalis chromobox protein, putative 0.0146 0.0526 0.0996
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0031 0.0059 0.0067
Schistosoma mansoni chromobox protein 0.0024 0.003 0.0034
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0062 0.0182 0.0369
Mycobacterium leprae PROBABLE BIFUNCTIONAL PENICILLIN-BINDING PROTEIN 1A/1B PONA1 (MUREIN POLYMERASE) (PBP1): PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE 0.1318 0.5272 0.9386
Leishmania major phosphoglycerate kinase B, cytosolic 0.0362 0.14 1
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0067 0.0203 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0168 0.0317
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.0184 0.1312
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.006 0.0175 0.0193
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0085
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.006 0.0175 0.0199
Giardia lamblia Sirtuin type 2 0.0017 0.0003 0.0003
Brugia malayi transcriptional regulator, Sir2 family protein 0.0017 0.0003 0.0008
Trypanosoma brucei DNA polymerase IV, putative 0.0208 0.0777 0.5549
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0002 0.0014
Echinococcus multilocularis lamin 0.0057 0.0162 0.0185
Brugia malayi ImpB/MucB/SamB family protein 0.0126 0.0443 0.1264
Leishmania major hypothetical protein, conserved 0.002 0.0014 0.0098
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0017 0.0003 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0047 0.0054
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0182 0.0343
Echinococcus granulosus jumonji domain containing 1A 0.002 0.0014 0.0016
Loa Loa (eye worm) hypothetical protein 0.0075 0.0237 0.0677
Schistosoma mansoni DNA helicase recq1 0.0031 0.0059 0.0067
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.003 0.0054
Giardia lamblia PHD finger protein 15 0.0062 0.0184 0.0376
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0054 0.0152 0.0287
Brugia malayi beta-NAC-like protein 0.0071 0.0219 0.0625
Toxoplasma gondii peptidylprolyl isomerase 0.0069 0.021 0.1503
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.008 0.0258 0.046
Brugia malayi 6-phosphofructokinase 0.0228 0.0856 0.2443
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.006 0.0175 0.1248
Loa Loa (eye worm) hypothetical protein 0.018 0.066 0.1883
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1217 0.4863 0.9223
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0031 0.0059 0.0169
Onchocerca volvulus 0.002 0.0012 0.0013
Brugia malayi jmjC domain containing protein 0.0075 0.0237 0.0676
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.003 0.0054
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0015 0.0105
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0072 0.0511
Brugia malayi Protein cec-1. 0.0024 0.003 0.0085
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0032 0.009
Trypanosoma cruzi DNA damage repair protein, putative 0.0039 0.0091 0.065
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0054 0.0152 0.0287
Loa Loa (eye worm) glutathione reductase 0.0049 0.0133 0.0378
Plasmodium falciparum flap endonuclease 1 0.0027 0.0043 0.0306
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0012 0.0014
Schistosoma mansoni lipoxygenase 0.0082 0.0265 0.0302
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.0047 0.0134
Loa Loa (eye worm) hypothetical protein 0.0082 0.0265 0.0757
Trypanosoma brucei trypanothione reductase 0.0049 0.0133 0.0948
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.0047 0.0134
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0047 0.0134
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0203 0.0756 0.086
Plasmodium falciparum DNA repair protein REV1, putative 0.0039 0.0091 0.065
Mycobacterium leprae PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) [INCLUDES: PENICILLIN-INSEN 0.1062 0.4235 0.7534
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0113 0.0389 0.0662
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0017 0.0001 0.0001
Schistosoma mansoni rotamase 0.007 0.0217 0.0247
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.003 0.0056
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.003 0.0054
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.003 0.0054
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0182 0.0343
Echinococcus granulosus flap endonuclease 1 0.0027 0.0043 0.0049
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0054 0.0152 0.0271
Loa Loa (eye worm) hypothetical protein 0.0075 0.0237 0.0677
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0027 0.0015
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0126 0.0445 0.318
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0031 0.0059 0.0067
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0022 0.0023 0.0026
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0175 0.0329
Loa Loa (eye worm) hypothetical protein 0.0138 0.0491 0.1401
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0201 0.0747 0.1415
Echinococcus multilocularis expressed protein 0.007 0.0217 0.0247
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.003 0.0054
Echinococcus granulosus phosphoglycerate kinase 1 0.0362 0.14 0.1592
Onchocerca volvulus 0.0075 0.0237 0.0577
Echinococcus multilocularis lysine specific demethylase 5A 0.0075 0.0237 0.0269
Trypanosoma brucei unspecified product 0.0087 0.0285 0.2033
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1217 0.4863 0.9223
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0066
Schistosoma mansoni phosphoglycerate kinase 0.0362 0.14 0.1592
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0012 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0219 0.0413
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0146 0.0526 0.3756
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0024 0.003 0.0034
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0182 0.0343
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0134
Trypanosoma brucei hypothetical protein, conserved 0.0075 0.0237 0.1695
Trypanosoma brucei phosphoinositide-specific phospholipase C 0.0019 0.0011 0.008
Trichomonas vaginalis phosphofructokinase, putative 0.0228 0.0856 0.1622
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.0408 0.0464
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0002 0.0014
Mycobacterium tuberculosis Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) 0.0166 0.0606 0.108
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.003 0.0034
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0002 0.0001
Echinococcus granulosus histone lysine methyltransferase setb 0.0126 0.0445 0.0506
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0208 0.0777 0.5549
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 11, putative 0.0017 0.0001 0.0009
Mycobacterium leprae conserved hypothetical protein 0.0075 0.0237 0.0391
Brugia malayi steroid hormone receptor 0.0028 0.0047 0.0134
Schistosoma mansoni chromatin regulatory protein sir2 0.0017 0.0003 0.0003
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0043 0.0306
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0091 0.065
Mycobacterium ulcerans Sir2-like regulatory protein 0.0017 0.0003 0.0001
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0228 0.0856 0.6117
Trypanosoma brucei DNA polymerase kappa, putative 0.0107 0.0367 0.2625
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0028 0.0047 0.0134
Brugia malayi hypothetical protein 0.0024 0.003 0.0085
Brugia malayi ImpB/MucB/SamB family protein 0.018 0.066 0.1883
Chlamydia trachomatis phosphoglycerate kinase 0.0362 0.14 0.1398
Loa Loa (eye worm) hypothetical protein 0.0062 0.0184 0.0525
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0217 0.041
Schistosoma mansoni intermediate filament proteins 0.0057 0.0162 0.0185
Trichomonas vaginalis DNA helicase recq, putative 0.0046 0.0119 0.0224
Mycobacterium tuberculosis Probable reductase 0.0113 0.0389 0.0693
Schistosoma mansoni phd/f-box containing protein 0.002 0.0014 0.0016
Schistosoma mansoni microtubule-associated protein tau 0.2186 0.879 1
Echinococcus multilocularis JmjC domain containing protein 4 0.002 0.0014 0.0016
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0024 0.003 0.0212
Echinococcus granulosus ubiquitin 0.0023 0.0025 0.0029
Brugia malayi Doublecortin family protein 0.002 0.0012 0.0035
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0044 0.0109 0.0124
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0028 0.0047 0.0054
Trichomonas vaginalis Heterochromatin protein, putative 0.0024 0.003 0.0054
Trypanosoma cruzi DNA polymerase kappa, putative 0.0208 0.0777 0.5549
Brugia malayi glutathione reductase 0.0049 0.0133 0.0378
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0074 0.0212
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.006 0.0175 0.1248
Echinococcus multilocularis chromatin regulatory protein sir2 0.0017 0.0003 0.0003
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0017 0.0003 0.0003
Loa Loa (eye worm) proteasome 26S subunit 0.0017 0.0001 0.0003
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0133 0.0378
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0002 0.0014
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0201 0.0747 0.1415
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0133 0.0151
Leishmania major DNA polymerase eta, putative 0.018 0.066 0.4715
Onchocerca volvulus Matrilysin homolog 0.0041 0.0098 0.0227
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0028 0.0047 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0219 0.0413
Giardia lamblia Pyruvate kinase 0.0035 0.0074 0.0151
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0002 0.0014
Mycobacterium leprae Probable transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) 0.0166 0.0606 0.1051
Treponema pallidum phosphoglycerate kinase 0.0362 0.14 0.1398
Plasmodium falciparum JmjC domain-containing protein, putative 0.002 0.0014 0.0098
Loa Loa (eye worm) glutaminase 2 0.056 0.2201 0.628
Echinococcus multilocularis jumonji domain containing 1A 0.002 0.0014 0.0016
Brugia malayi Pyruvate kinase, M2 isozyme 0.0035 0.0074 0.0212
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0268 0.0305
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0012 0.0014
Onchocerca volvulus 0.0024 0.003 0.0057
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0002 0.0014
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.0408 0.0464
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1217 0.4863 0.9223
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0069 0.021 0.1503
Schistosoma mansoni chromobox protein 0.0024 0.003 0.0034
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0069 0.021 0.1503
Schistosoma mansoni chromatin regulatory protein sir2 0.0017 0.0003 0.0003
Mycobacterium ulcerans DNA polymerase IV 0.0208 0.0777 0.0864
Echinococcus multilocularis Chromo domain 0.0024 0.003 0.0034
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0022 0.0023 0.0065
Plasmodium vivax hypothetical protein, conserved 0.002 0.0015 0.0105
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0133 0.0471 0.3366
Plasmodium vivax phospholipase C-like, putative 0.0018 0.0007 0.0049
Brugia malayi Associated with TFs and helicases family protein 0.0024 0.003 0.0085
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0017 0.0003 0.0003
Plasmodium falciparum pyruvate kinase 2 0.0018 0.0005 0.0038
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0133 0.0471 0.3366
Brugia malayi hypothetical protein 0.0023 0.0025 0.0072
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0017 0.0001 0.0001
Mycobacterium tuberculosis Probable penicillin-binding protein PbpA 0.1403 0.5616 1
Plasmodium falciparum heterochromatin protein 1 0.0024 0.003 0.0212
Plasmodium vivax hypothetical protein, conserved 0.0075 0.0237 0.1695
Schistosoma mansoni RAR-like nuclear receptor 0.0028 0.0047 0.0054
Trypanosoma brucei DNA polymerase IV, putative 0.0188 0.0694 0.4958
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.006 0.0175 0.0498
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0043 0.0107 0.0763
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0179 0.0658 0.0748
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0027 0.0192
Brugia malayi beta-lactamase 0.0075 0.0237 0.0677
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0201 0.0747 0.2131
Onchocerca volvulus Protein ultraspiracle homolog 0.0028 0.0047 0.0101
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0017 0.0003 0.0019
Toxoplasma gondii exonuclease III APE 0.006 0.0175 0.1248
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0014 0.0098
Mycobacterium leprae Probable penicillin-binding protein PbpA 0.1403 0.5616 1
Plasmodium falciparum nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.03 0.115 0.8216
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0275 0.1049 0.7492
Brugia malayi hypothetical protein 0.002 0.0012 0.0035
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0034 0.0072 0.0511
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0028 0.0047 0.0054
Chlamydia trachomatis pyruvate kinase 0.0035 0.0074 0.0072
Trichomonas vaginalis phosphofructokinase, putative 0.0228 0.0856 0.1622
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.008 0.0258 0.0737
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0085
Loa Loa (eye worm) hypothetical protein 0.008 0.0258 0.0737
Loa Loa (eye worm) hypothetical protein 0.0126 0.0445 0.127
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0069 0.021 0.0427
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0228 0.0856 0.6117
Mycobacterium ulcerans penicillin-binding lipoprotein 0.0781 0.3096 0.3451
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0268 0.0305
Schistosoma mansoni hypothetical protein 0.052 0.2041 0.2322
Loa Loa (eye worm) ICD-1 protein 0.0071 0.0219 0.0625
Echinococcus granulosus peregrin 0.0062 0.0184 0.0209
Schistosoma mansoni phosphoglycerate kinase 0.0362 0.14 0.1592
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0028 0.0047 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0028 0.0047 0.0134
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0027 0.0025
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0179 0.0658 0.0748
Brugia malayi Phosphoglycerate kinase 0.0133 0.0471 0.1344
Leishmania major basic transcription factor 3a, putative 0.0071 0.0219 0.1565
Mycobacterium tuberculosis Probable lipase LipE 0.0075 0.0237 0.0422
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0134
Plasmodium vivax hypothetical protein, conserved 0.0062 0.0184 0.1314
Loa Loa (eye worm) hypothetical protein 0.0106 0.0363 0.1037
Brugia malayi 6-phosphofructokinase 0.0228 0.0856 0.2443
Giardia lamblia Fructose-bisphosphate aldolase 0.1217 0.4863 1
Trichomonas vaginalis glutaminase, putative 0.056 0.2201 0.4174
Brugia malayi Valyl-tRNA synthetase 0.0024 0.003 0.0085
Treponema pallidum fructose-bisphosphate aldolase 0.1217 0.4863 0.4862
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0249 0.0941 0.2684
Schistosoma mansoni pyruvate kinase 0.0035 0.0074 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0219 0.0413
Mycobacterium ulcerans hypothetical protein 0.0075 0.0237 0.0263
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.008 0.0258 0.1846
Schistosoma mansoni rab6-interacting 0.002 0.0012 0.0014
Brugia malayi Pyruvate kinase, muscle isozyme 0.0035 0.0074 0.0212
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0134
Echinococcus granulosus bloom syndrome protein 0.0046 0.0119 0.0136
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0072
Loa Loa (eye worm) jmjC domain-containing protein 0.0128 0.0451 0.1288
Giardia lamblia DINP protein human, muc B family 0.0146 0.0526 0.1079
Trichomonas vaginalis DNA helicase recq, putative 0.0034 0.0072 0.0133
Schistosoma mansoni pyruvate kinase 0.0018 0.0005 0.0006
Echinococcus multilocularis ubiquitin 0.0023 0.0025 0.0029
Echinococcus granulosus phd:f box containing protein 0.002 0.0014 0.0016
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0074 0.0169
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0069 0.021 0.1503
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0039
Schistosoma mansoni flap endonuclease-1 0.0025 0.0032 0.0037
Brugia malayi chromobox protein homolog 3 0.0082 0.0265 0.0757
Mycobacterium ulcerans beta-lactamase 0.0075 0.0237 0.0263
Trypanosoma cruzi transcription factor btf3, putative 0.0071 0.0219 0.1565
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0017 0.0003 0.0003
Loa Loa (eye worm) 6-phosphofructokinase 0.0228 0.0856 0.2443
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0228 0.0856 0.1497
Loa Loa (eye worm) helicase 0.0024 0.003 0.0085
Trichomonas vaginalis esterase, putative 0.0075 0.0237 0.0448
Brugia malayi glutaminase DH11.1 0.056 0.2201 0.628
Trichomonas vaginalis set domain proteins, putative 0.1004 0.3999 0.7584
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0054 0.0152 0.1089
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0133 0.0471 0.3366
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0054 0.0152 0.1089
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0043 0.0306
Trichomonas vaginalis rotamase, putative 0.007 0.0217 0.041
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0017 0.0001 0.0009
Plasmodium falciparum small ubiquitin-related modifier 0.0065 0.0197 0.1408
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0027 0.0025
Echinococcus multilocularis bloom syndrome protein 0.0046 0.0119 0.0136
Onchocerca volvulus 0.002 0.0012 0.0013
Echinococcus multilocularis Chromobox protein 3 0.0024 0.003 0.0034
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0062 0.0184 0.1312
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0003 0.0003
Brugia malayi F/Y-rich N-terminus family protein 0.0025 0.0034 0.0096
Mycobacterium ulcerans esterase/lipase LipP 0.0075 0.0237 0.0263
Trypanosoma brucei DNA polymerase kappa, putative 0.0208 0.0777 0.5549
Loa Loa (eye worm) PHD-finger family protein 0.0062 0.0184 0.0525
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0075 0.0237 0.0422
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0043 0.0306
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0085
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0182 0.0343
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0133 0.0151
Brugia malayi exodeoxyribonuclease III family protein 0.006 0.0175 0.0498
Schistosoma mansoni phosphatidylserine receptor 0.002 0.0014 0.0016
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.003 0.0212
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0024 0.003 0.0034
Loa Loa (eye worm) hypothetical protein 0.0083 0.0268 0.0764
Onchocerca volvulus 0.0019 0.0011 0.0011
Plasmodium falciparum glutathione reductase 0.0017 0.0002 0.0014
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0014 0.0039
Loa Loa (eye worm) hypothetical protein 0.0121 0.0425 0.1212
Loa Loa (eye worm) hypothetical protein 0.0033 0.0064 0.0184
Leishmania major silent information regulator 2, putative 0.0017 0.0003 0.0019
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1217 0.4863 0.9223
Loa Loa (eye worm) Plcb4 protein 0.0018 0.0007 0.0019
Brugia malayi phosphofructokinase 0.0228 0.0856 0.2443
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0056 0.0159
Loa Loa (eye worm) heterochromatin protein 1 0.0146 0.0526 0.1501
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0012 0.0087
Schistosoma mansoni DNA helicase recq5 0.0031 0.0059 0.0067
Mycobacterium ulcerans hypothetical protein 0.0021 0.0018 0.0018
Echinococcus multilocularis chromobox protein 1 0.0146 0.0526 0.0598
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0113 0.0389 0.0693
Echinococcus multilocularis beta LACTamase domain containing family member 0.0075 0.0237 0.027
Brugia malayi beta-lactamase family protein 0.0075 0.0237 0.0677
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0027 0.0192
Schistosoma mansoni chromatin regulatory protein sir2 0.0017 0.0003 0.0003
Mycobacterium leprae Probable penicillin-binding membrane protein PbpB 0.0651 0.257 0.4558
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0027 0.0192
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0043 0.0079
Giardia lamblia Sgs1 DNA helicase, putative 0.0031 0.0059 0.0119
Leishmania major pyruvate kinase 0.0035 0.0074 0.0532
Brugia malayi beta-lactamase family protein 0.0075 0.0237 0.0677
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0028 0.0047 0.0054
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.002 0.0014 0.0098
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0362 0.14 0.2653
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0003 0.0003
Trypanosoma brucei unspecified product 0.0087 0.0285 0.2033
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.003 0.0054
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0002 0.0014
Brugia malayi jmjC domain containing protein 0.002 0.0014 0.0039
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0002 0.0002
Schistosoma mansoni glutaminase 0.056 0.2201 0.2504
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0175 0.1248
Echinococcus multilocularis pyruvate kinase 0.0018 0.0005 0.0006
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0203 0.0756 0.086
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.002
Brugia malayi hypothetical protein 0.002 0.0012 0.0035
Trichomonas vaginalis chromobox protein, putative 0.0088 0.029 0.0549
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0133 0.0471 0.3366
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0047 0.0054
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0043 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0107 0.0367 0.2625
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0018 0.0007 0.0008
Trichomonas vaginalis ubiquitin, putative 0.0023 0.0025 0.0045
Onchocerca volvulus Cell death protein 3 homolog 0.0033 0.0064 0.0144
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0028 0.0047 0.0101
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0028 0.0047 0.0134
Echinococcus multilocularis geminin 0.052 0.2041 0.2322
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0197 0.0371
Schistosoma mansoni thyroid hormone receptor 0.0028 0.0047 0.0054
Echinococcus granulosus jumonji domain containing protein 0.0086 0.0282 0.0321
Echinococcus multilocularis 6 phosphofructokinase 0.0228 0.0856 0.0974
Mycobacterium leprae POSSIBLE PENICILLIN-BINDING LIPOPROTEIN 0.0781 0.3096 0.5498
Onchocerca volvulus 0.0064 0.0193 0.0467
Schistosoma mansoni hypothetical protein 0.0026 0.0038 0.0043
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0126 0.0443 0.1264
Chlamydia trachomatis endonuclease IV 0.008 0.0258 0.0257
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0022 0.0023 0.0041
Loa Loa (eye worm) hypothetical protein 0.0057 0.0162 0.0463
Mycobacterium tuberculosis Conserved protein 0.0075 0.0237 0.0422
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0074 0.0139
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0012 0.0087
Echinococcus granulosus geminin 0.052 0.2041 0.2322
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0133 0.0948
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.003 0.0054
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0035 0.0074 0.0132
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0075 0.0237 0.0422
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0019
Plasmodium vivax 6-phosphofructokinase, putative 0.0062 0.0182 0.1301
Schistosoma mansoni jumonji domain containing protein 0.0161 0.0586 0.0667
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.0019 0.0011 0.0032
Entamoeba histolytica exodeoxyribonuclease III, putative 0.006 0.0175 0.0354
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0201 0.0747 0.1415
Loa Loa (eye worm) hypothetical protein 0.0064 0.0193 0.0552
Onchocerca volvulus Alhambra homolog 0.0062 0.0184 0.0443
Mycobacterium tuberculosis Probable hydrolase 0.0075 0.0237 0.0422
Trypanosoma brucei DNA polymerase kappa, putative 0.0121 0.0425 0.3034
Mycobacterium ulcerans bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 0.1062 0.4235 0.4722
Echinococcus multilocularis phd:f box containing protein 0.002 0.0014 0.0016
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0024 0.003 0.0085
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0201 0.0747 0.0831
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0032 0.0059
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0201 0.0747 0.2131
Schistosoma mansoni lamin 0.0057 0.0162 0.0185
Onchocerca volvulus 0.015 0.0542 0.1341
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0062 0.0182 0.1301
Entamoeba histolytica phosphofructokinase, putative 0.0228 0.0856 0.1756
Entamoeba histolytica recQ family helicase, putative 0.0034 0.0072 0.0142
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0075 0.0237 0.0677
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0074 0.0169
Echinococcus multilocularis chromobox protein 1 0.0146 0.0526 0.0598
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.0005 0.0038
Brugia malayi Matrixin family protein 0.0018 0.0007 0.002
Mycobacterium tuberculosis Probable oxidoreductase 0.0125 0.044 0.0783
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.0005 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0028 0.0047 0.0134
Plasmodium vivax small ubiquitin-related modifier, putative 0.0065 0.0197 0.1408
Toxoplasma gondii NAC domain-containing protein 0.0071 0.0219 0.1565
Trypanosoma cruzi small ubiquitin protein, putative 0.0065 0.0197 0.1408
Toxoplasma gondii small ubiquitin family modifier, putative 0.0065 0.0197 0.1408
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0035
Loa Loa (eye worm) hypothetical protein 0.0026 0.0039 0.0112
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0275 0.1049 0.2152
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0018 0.0033
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0012 0.0014
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.003 0.0034
Loa Loa (eye worm) hypothetical protein 0.0075 0.0237 0.0677
Mycobacterium ulcerans 6-phosphofructokinase 0.0228 0.0856 0.0953
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0201 0.0747 0.1531
Echinococcus multilocularis peregrin 0.0062 0.0184 0.0209
Brugia malayi ecdysteroid receptor 0.0028 0.0047 0.0134
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0043 0.0306
Echinococcus multilocularis 1 phosphatidylinositol 4,5 bisphosphate 0.0019 0.0011 0.0013
Onchocerca volvulus 0.0024 0.003 0.0057
Leishmania major phospholipase c-like protein 0.0019 0.0011 0.008
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.015 0.0542 0.0617
Giardia lamblia Sentrin 0.0065 0.0197 0.0403
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0091 0.065
Trypanosoma brucei DNA polymerase kappa, putative 0.0208 0.0777 0.5549
Onchocerca volvulus 0.0019 0.0011 0.0011
Schistosoma mansoni jumonji domain containing protein 0.002 0.0014 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.0047 0.0134
Echinococcus multilocularis apoptotic protease activating factor 1 0.0033 0.0064 0.0073
Schistosoma mansoni pyruvate kinase 0.0035 0.0074 0.0085
Trypanosoma brucei phosphoglycerate kinase, putative 0.0133 0.0471 0.3366
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0003 0.0003
Plasmodium vivax glutathione reductase, putative 0.0049 0.0133 0.0948
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0228 0.0856 0.1525
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0024 0.003 0.0212
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0028 0.0047 0.0054
Echinococcus granulosus chromobox protein 1 0.0146 0.0526 0.0598
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0059 0.0422
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0133 0.0948
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0059 0.0422
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0008
Mycobacterium tuberculosis Probable esterase LipL 0.0075 0.0237 0.0422
Trypanosoma brucei DNA polymerase kappa, putative 0.0146 0.0526 0.3756
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0047 0.0054
Schistosoma mansoni polycystin 1-related 0.002 0.0012 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0265 0.0501
Schistosoma mansoni loxhd1 0.002 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0085
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0018 0.0052
Schistosoma mansoni coup transcription factor 0.0028 0.0047 0.0054
Plasmodium vivax DNA repair protein REV1, putative 0.0039 0.0091 0.065
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0022 0.0023 0.0163
Trichomonas vaginalis chromobox protein, putative 0.0088 0.029 0.0549
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0075 0.0237 0.0422
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0017 0.0003 0.0003
Echinococcus granulosus pyruvate kinase 0.0018 0.0005 0.0006
Trypanosoma brucei chrX additional, unordered contigs 0.0039 0.0091 0.065
Entamoeba histolytica hypothetical protein 0.0023 0.0027 0.005
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.003 0.0212
Brugia malayi Matrixin family protein 0.0018 0.0007 0.002
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0162 0.0463
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0054 0.0152 0.1089
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.002 0.0014 0.0016
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0014 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.003 0.0054
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.0184 0.1312
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0125 0.044 0.0783
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0031 0.0059 0.0067
Echinococcus multilocularis ecdysone induced protein 78C 0.0028 0.0047 0.0054
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0062 0.0182 0.018
Mycobacterium ulcerans serine/threonine-protein kinase B PknB 0.0166 0.0606 0.0674
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1217 0.4863 0.9223
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.003 0.0054
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0028 0.0047 0.0054
Onchocerca volvulus 0.0028 0.0047 0.0101
Trypanosoma cruzi small ubiquitin protein, putative 0.0065 0.0197 0.1408
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0028 0.0047 0.0054
Treponema pallidum hypothetical protein 0.0166 0.0606 0.0605
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0179 0.0658 0.0731
Brugia malayi PHD-finger family protein 0.002 0.0015 0.0042
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0033 0.0064 0.0184
Echinococcus granulosus expressed protein 0.007 0.0217 0.0247
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1217 0.4863 0.9223
Toxoplasma gondii phosphofructokinase PFKII 0.0062 0.0182 0.1301
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0362 0.14 1
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0017 0.0003 0.0003
Echinococcus multilocularis FTZ F1 alpha 0.0028 0.0047 0.0054
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0.0015 0.0105
Plasmodium falciparum thioredoxin reductase 0.0017 0.0002 0.0014
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0028 0.0047 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0028 0.0047 0.0134
Echinococcus granulosus chromobox protein 1 0.0146 0.0526 0.0598
Echinococcus granulosus transcription factor Dp 1 0.0159 0.0579 0.0658
Toxoplasma gondii PHD-finger domain-containing protein 0.0062 0.0184 0.1314
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0275 0.1049 0.7492
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0017 0.0003 0.0019
Onchocerca volvulus 0.0075 0.0237 0.0577
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0134
Schistosoma mansoni blooms syndrome DNA helicase 0.003 0.0055 0.0062
Echinococcus granulosus dna polymerase eta 0.018 0.066 0.0751
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.008 0.0258 0.1846
Leishmania major DNA polymerase kappa, putative 0.0039 0.0091 0.065
Echinococcus multilocularis thyroid hormone receptor alpha 0.0028 0.0047 0.0054
Echinococcus multilocularis neuropeptide receptor A26 0.0489 0.1915 0.2179
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0228 0.0856 0.0854
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0024 0.003 0.0212
Giardia lamblia Hypothetical protein 0.0017 0.0003 0.0003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0208 0.0777 0.5549
Brugia malayi nuclear hormone receptor 0.0028 0.0047 0.0134
Schistosoma mansoni hypothetical protein 0.002 0.0015 0.0017
Loa Loa (eye worm) matrixin family protein 0.0041 0.0098 0.0278
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0062 0.0184 0.0346
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0042 0.0302
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0002 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0208 0.0777 0.5549
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0028 0.0047 0.0054
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0047 0.0054
Trypanosoma brucei pyruvate kinase 1 0.0035 0.0074 0.0532
Toxoplasma gondii histone deacetylase SIR2-like 0.0017 0.0003 0.0019
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0074 0.0532
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0133 0.0236
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0162 0.0463
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0275 0.1049 0.7492
Treponema pallidum hypothetical protein 0.03 0.115 0.1148
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.002 0.0014 0.0098
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.002
Mycobacterium tuberculosis Possible penicillin-binding lipoprotein 0.0781 0.3096 0.5512
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0088 0.029 0.071
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.003 0.0056
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0268 0.0305
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0028 0.0047 0.0134
Entamoeba histolytica hypothetical protein 0.0024 0.003 0.0056
Brugia malayi Thioredoxin reductase 0.0049 0.0133 0.0378
Schistosoma mansoni chromatin regulatory protein sir2 0.0054 0.0152 0.0173
Brugia malayi jmjC domain containing protein 0.0203 0.0756 0.2156
Loa Loa (eye worm) jmjC domain-containing protein 0.0075 0.0237 0.0676
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0027 0.0025
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0043 0.0306
Trichomonas vaginalis chromobox protein, putative 0.0146 0.0526 0.0996
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0275 0.1049 0.2991
Echinococcus granulosus JmjC domain containing protein 4 0.002 0.0014 0.0016
Loa Loa (eye worm) hypothetical protein 0.0075 0.0237 0.0677
Treponema pallidum exodeoxyribonuclease (exoA) 0.006 0.0175 0.0173

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influx at 25 uM ChEMBL. 18394886
Activity (binding) Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influx at 10 uM ChEMBL. 18394886
Activity (binding) 0 Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influx at 10 uM ChEMBL. 18394886
Activity (binding) 0 Corrector activity at human CFTR deltaF508 mutant expressed in FRT cells assessed as iodide influx at 25 uM ChEMBL. 18394886

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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