Detailed information for compound 549195

Basic information

Technical information
  • TDR Targets ID: 549195
  • Name: hydrogen sulfate; 2-(5-hydroxy-1H-indol-3-yl) ethylammonium
  • MW: 274.294 | Formula: C10H14N2O5S
  • H donors: 4 H acceptors: 5 LogP: -2.73 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-]S(=O)(=O)O.[NH3+]CCc1c[nH]c2c1cc(O)cc2
  • InChi: 1S/C10H12N2O.H2O4S/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10;1-5(2,3)4/h1-2,5-6,12-13H,3-4,11H2;(H2,1,2,3,4)
  • InChiKey: BYNFKPVCVMZGOI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • hydrogen sulfate; 2-(5-hydroxy-1H-indol-3-yl)ethylazanium
  • 2-(5-hydroxy-1H-indol-3-yl)ethylammonium bisulfate
  • 3-(2-aminoethyl)-1H-indol-5-ol; sulfuric acid
  • 3-(2-azanylethyl)-1H-indol-5-ol; sulfuric acid
  • 5-hydroxytryptamine O-sulfate
  • 16310-20-6
  • 2906-14-1
  • 1H-Indol-5-ol, 3-(2-aminoethyl)-, sulfate (salt) (9CI)
  • 3-(2-Aminoethyl)-1H-indol-5-ol sulfate (salt)
  • 5-Hydroxytryptamine sulfate
  • INDOL-5-OL, 3-(2-AMINOETHYL)-, SULFATE
  • Serotonin sulfate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0038 0.0121 0.0121
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0023 0.009
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0038 0.012 0.012
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0011 0.0011
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.003 0.0083 0.0083
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0038 0.012 0.012
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0023 0.0284
Echinococcus multilocularis musashi 0.0054 0.0203 0.0203
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0023 0.0284
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0038 0.012 0.1137
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0139 0.1314
Schistosoma mansoni ap endonuclease 0.0018 0.0023 0.0023
Onchocerca volvulus 0.0035 0.0107 0.0441
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0083 0.0083
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0021 0.0038 0.0356
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0038 0.012 0.012
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0174 0.0799 0.0799
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0083 0.0339
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0107 0.0446
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0083 0.0083
Schistosoma mansoni coup transcription factor 0.003 0.0083 0.0083
Brugia malayi hypothetical protein 0.0039 0.0126 0.0126
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0038 0.012 0.012
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0011 0.0011
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0003 0.0003
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0122 0.2197
Brugia malayi Muscleblind-like protein 0.0451 0.2188 0.2188
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0043 0.0043
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0021 0.0038 0.0548
Brugia malayi nuclear receptor RXR 0.0016 0.0011 0.0011
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0108 0.0473 0.592
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0385 0.0385
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0023 0.0023
Echinococcus granulosus inositol monophosphatase 1 0.0073 0.0296 0.0296
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0003 0.0003
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0038 0.012 0.012
Trypanosoma brucei protein kinase, putative 0.005 0.018 0.2254
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0023 0.0284
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0083 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0062 0.0256
Schistosoma mansoni hypothetical protein 0.0107 0.0466 0.0466
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0234 0.3434
Plasmodium vivax ornithine aminotransferase, putative 0.0021 0.0038 0.0193
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0038 0.012 0.1137
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Brugia malayi nuclear hormone receptor 0.003 0.0083 0.0083
Brugia malayi hypothetical protein 0.0038 0.012 0.012
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0003 0.0003
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0234 0.2213
Schistosoma mansoni cpg binding protein 0.0122 0.0543 0.0543
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0385 0.0385
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0139 0.0139
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0003 0.0003
Loa Loa (eye worm) CYP4Cod1 0.0022 0.0043 0.0043
Echinococcus granulosus mixed lineage leukemia protein mll 0.0031 0.0086 0.0086
Loa Loa (eye worm) MBOAT family protein 0.2014 1 1
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0108 0.0447
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0248 0.1171 0.1171
Loa Loa (eye worm) hypothetical protein 0.0223 0.1046 0.1046
Trypanosoma cruzi GUP1, putative 0.0174 0.0799 1
Brugia malayi hypothetical protein 0.0039 0.0126 0.0126
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0021 0.0038 0.0553
Echinococcus multilocularis sterol O acyltransferase 1 0.0174 0.0799 0.0799
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0107 0.1015
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Echinococcus granulosus mitogen activated protein kinase 0.005 0.018 0.018
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0174 0.0799 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0122 0.1274
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0062 0.0256
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0083 0.0339
Trichomonas vaginalis conserved hypothetical protein 0.0174 0.0799 0.3359
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0083 0.0083
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0385 0.0385
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0083 0.0083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0108 0.0473 0.1986
Echinococcus granulosus lysosomal alpha glucosidase 0.0159 0.0727 0.0727
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0003 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0083 0.0083
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0174 0.0799 0.0799
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0126 0.0126
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0083 0.0083
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0083 0.0083
Brugia malayi hypothetical protein 0.0016 0.0011 0.0011
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0023 0.009
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0038 0.012 0.012
Echinococcus multilocularis ubiquitin specific protease 41 0.0108 0.0473 0.0473
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0108 0.0473 0.592
Onchocerca volvulus 0.0116 0.051 0.214
Echinococcus multilocularis sodium and chloride dependent glycine 0.0038 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0108 0.0473 0.0473
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0062 0.0256
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0083 0.0339
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0107 0.1015
Schistosoma mansoni alpha glucosidase 0.0035 0.0108 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0062 0.0256
Schistosoma mansoni lipoxygenase 0.01 0.0432 0.0432
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0108 0.0447
Schistosoma mansoni inositol monophosphatase 0.0073 0.0296 0.0296
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.018 0.2254
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0083 0.0083
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0038 0.0121 0.0121
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0083 0.0083
Onchocerca volvulus Huntingtin homolog 0.0125 0.0557 0.2338
Brugia malayi acetyltransferase, GNAT family protein 0.0141 0.0638 0.0638
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0234 0.0234
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0083 0.0083
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0083 0.0083
Trichomonas vaginalis set domain proteins, putative 0.0489 0.2375 1
Trypanosoma brucei glycerol uptake protein, putative 0.0174 0.0799 1
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0203 0.0203
Trichomonas vaginalis CMGC family protein kinase 0.005 0.018 0.0753
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.015 0.0682 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Schistosoma mansoni ap endonuclease 0.0018 0.0023 0.0023
Loa Loa (eye worm) solute carrier family 6 member 4 0.0223 0.1046 0.1046
Leishmania major hypothetical protein, conserved 0.0174 0.0799 1
Brugia malayi F/Y-rich N-terminus family protein 0.0038 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0451 0.2188 0.2188
Loa Loa (eye worm) histone methyltransferase 0.0038 0.0121 0.0121
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.025 0.2364
Leishmania major hypothetical protein, conserved 0.0035 0.0107 0.1344
Loa Loa (eye worm) hypothetical protein 0.0125 0.0557 0.0557
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0062 0.0256
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0108 0.0108
Brugia malayi beta-lactamase family protein 0.0035 0.0107 0.0107
Echinococcus granulosus sodium and chloride dependent glycine 0.0038 0.012 0.012
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0023 0.0284
Leishmania major cytochrome p450-like protein 0.0022 0.0043 0.0535
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0038 0.012 0.012
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0038 0.012 0.012
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0021 0.0038 0.0553
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0174 0.0799 0.0799
Schistosoma mansoni nuclear hormone receptor 0.003 0.0083 0.0083
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0011
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0003 0.0003
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0223 0.1046 0.1046
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.0086 0.0086
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0062 0.0256
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0011 0.0011
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0107 0.0446
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0038 0.012 0.012
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0107 0.0446
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0108 0.0473 0.0473
Loa Loa (eye worm) hypothetical protein 0.0038 0.012 0.012
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0038 0.012 0.012
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0021 0.0038 0.0356
Echinococcus granulosus sterol O acyltransferase 1 0.0174 0.0799 0.0799
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0003 0.0003
Plasmodium falciparum ornithine aminotransferase 0.0021 0.0038 0.0193
Brugia malayi Cytochrome P450 family protein 0.0051 0.0186 0.0186
Trichomonas vaginalis transmembrane protein nessy, putative 0.0174 0.0799 0.3359
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0049 0.0177 0.0177
Onchocerca volvulus 0.0039 0.0126 0.0521
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0107 0.1574
Loa Loa (eye worm) hypothetical protein 0.003 0.0083 0.0083
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.018 0.2254
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.018 0.2254
Schistosoma mansoni loxhd1 0.0039 0.0126 0.0126
Mycobacterium ulcerans hypothetical protein 0.0035 0.0107 0.1574
Brugia malayi Inositol-1 0.0073 0.0296 0.0296
Onchocerca volvulus 0.0054 0.0203 0.0846
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0083 0.0083
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0107 0.0107
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0021 0.0038 0.0038
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.018 0.2254
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.025 0.025
Plasmodium vivax amine transporter, putative 0.0038 0.012 0.1257
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0043 0.0043
Trichomonas vaginalis CMGC family protein kinase 0.005 0.018 0.0753
Schistosoma mansoni sodium/chloride dependent transporter 0.0038 0.0122 0.0122
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0126 0.0126
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0174 0.0799 0.0799
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0083 0.0083
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0083 0.0083
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.0727 0.0727
Mycobacterium tuberculosis Conserved protein 0.0035 0.0107 0.1015
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0021 0.0038 0.0356
Loa Loa (eye worm) hhat protein 0.0174 0.0799 0.0799
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0174 0.0799 1
Brugia malayi diacylglycerol acyltransferase 0.0174 0.0799 0.0799
Treponema pallidum sodium- and chloride- dependent transporter 0.0223 0.1046 1
Schistosoma mansoni nuclear receptor 0.0014 0.0003 0.0003
Trypanosoma cruzi glycerol uptake protein, putative 0.0174 0.0799 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.018 0.2254
Loa Loa (eye worm) hypothetical protein 0.0223 0.1046 0.1046
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0385 0.0385
Brugia malayi Pre-SET motif family protein 0.0064 0.025 0.025
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.025 0.025
Trichomonas vaginalis CMGC family protein kinase 0.005 0.018 0.0753
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0021 0.0038 0.0553
Leishmania major glycerol uptake protein, putative 0.0174 0.0799 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0108 0.0473 0.0473
Loa Loa (eye worm) hypothetical protein 0.003 0.0083 0.0083
Echinococcus multilocularis neuropeptide s receptor 0.0471 0.2286 0.2286
Loa Loa (eye worm) serotonin transporter b 0.0223 0.1046 0.1046
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.0086 0.0086
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0174 0.0799 0.0799
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0011
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.018 0.2254
Trichomonas vaginalis esterase, putative 0.0035 0.0107 0.0446
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0108 0.1347
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.025 0.025
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0141 0.0638 0.0638
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.015 0.0682 1
Echinococcus granulosus lamin dm0 0.0054 0.0203 0.0203
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0003 0.0003
Echinococcus multilocularis ornithine aminotransferase 0.0021 0.0038 0.0038
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0108 0.0473 0.592
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0108 0.0447
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.025 0.025
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0011
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.2014 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0083 0.0083
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.2014 1 1
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0038 0.012 0.012
Onchocerca volvulus 0.0039 0.0126 0.0521
Toxoplasma gondii exonuclease III APE 0.0018 0.0023 0.0215
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0038 0.012 0.012
Onchocerca volvulus Huntingtin homolog 0.0125 0.0557 0.2338
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.018 0.018
Brugia malayi nuclear receptor RXR 0.0014 0.0003 0.0003
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0083 0.0083
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0107 0.1015
Echinococcus granulosus intermediate filament protein 0.0054 0.0203 0.0203
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0514 0.0514
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0011 0.0011
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.015 0.0682 0.2868
Echinococcus granulosus FTZ F1 alpha 0.003 0.0083 0.0083
Echinococcus multilocularis cpg binding protein 0.0122 0.0543 0.0543
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0451 0.2188 0.2188
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0003 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.025 0.025
Brugia malayi hypothetical protein 0.0242 0.114 0.114
Loa Loa (eye worm) hypothetical protein 0.003 0.0083 0.0083
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0038 0.012 0.012
Brugia malayi hypothetical protein 0.0107 0.0466 0.0466
Brugia malayi MAP kinase sur-1 0.005 0.018 0.018
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0108 0.0473 0.0473
Echinococcus granulosus muscleblind protein 0.0451 0.2188 0.2188
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.0043 0.0535
Loa Loa (eye worm) hypothetical protein 0.003 0.0083 0.0083
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0139 0.0579
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0234 0.0234
Entamoeba histolytica hypothetical protein 0.0107 0.0466 0.5707
Toxoplasma gondii ABC1 family protein 0.0035 0.0107 0.1015
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0174 0.0799 1
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0174 0.0799 0.0799
Schistosoma mansoni survival motor neuron protein 0.0049 0.0177 0.0177
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0107 0.1344
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0107 0.0446
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0065 0.0258 0.2439
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0077 0.0077
Plasmodium falciparum LCCL domain-containing protein 0.0039 0.0126 0.1336
Loa Loa (eye worm) hypothetical protein 0.003 0.0083 0.0083
Entamoeba histolytica hypothetical protein 0.0174 0.0799 1
Echinococcus multilocularis RUN 0.0039 0.0126 0.0126
Echinococcus multilocularis lamin 0.0054 0.0203 0.0203
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0022 0.0043 0.0627
Schistosoma mansoni cpg binding protein 0.0116 0.051 0.051
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0083 0.0083
Echinococcus multilocularis serotonin transporter 0.0223 0.1046 0.1046
Trichomonas vaginalis helicase, putative 0.0026 0.0062 0.0256
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.018 0.018
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0226 0.0226
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0122 0.1274
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0021 0.0038 0.0356
Onchocerca volvulus 0.003 0.0083 0.0339
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0003 0.0003
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0171 0.0784 0.0784
Schistosoma mansoni hypothetical protein 0.0039 0.0126 0.0126
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0038 0.012 0.012
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0125 0.0557 0.0557
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0174 0.0799 0.7554
Loa Loa (eye worm) hypothetical protein 0.0035 0.0107 0.0107
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0003 0.0003
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0141 0.0638 0.0638
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0234 0.2932
Echinococcus granulosus dnaJ subfamily B 0.1237 0.6115 0.6115
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0023 0.0333
Echinococcus multilocularis dnaJ subfamily B 0.1237 0.6115 0.6115
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0062 0.0256
Mycobacterium ulcerans lipase LipD 0.0035 0.0107 0.1574
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0011 0.0011
Echinococcus granulosus ubiquitin specific protease 41 0.0108 0.0473 0.0473
Loa Loa (eye worm) hypothetical protein 0.0038 0.012 0.012
Schistosoma mansoni polycystin 1-related 0.0039 0.0126 0.0126
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0038 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0054 0.0203 0.0203
Entamoeba histolytica hypothetical protein 0.0107 0.0466 0.5707
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0038 0.012 0.012
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0385 0.0385
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0108 0.0473 0.0473
Loa Loa (eye worm) hypothetical protein 0.0035 0.0107 0.0107
Giardia lamblia Kinase, CMGC MAPK 0.005 0.018 0.3495
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0203 0.0203
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0083 0.0083
Toxoplasma gondii hypothetical protein 0.0174 0.0799 0.7554
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0003 0.0003
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0107 0.1015
Onchocerca volvulus 0.0054 0.0203 0.0846
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0083 0.0083
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0107 0.1574
Brugia malayi MBOAT family protein 0.0174 0.0799 0.0799
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0003 0.0003
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0514 0.0514
Echinococcus multilocularis survival motor neuron protein 1 0.0242 0.114 0.114
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0108 0.0108
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0021 0.0038 0.0357
Brugia malayi hypothetical protein 0.0014 0.0003 0.0003
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0038 0.012 0.012
Echinococcus granulosus Aminotransferase class III 0.0021 0.0038 0.0038
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0031 0.0086 0.0086
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0003 0.0003
Plasmodium vivax multidomain scavenger receptor, putative 0.0039 0.0126 0.1336
Echinococcus granulosus zinc finger protein 0.184 0.9132 0.9132
Plasmodium falciparum transporter, putative 0.0038 0.012 0.1257
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0174 0.0799 0.0799
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0107 0.1015
Brugia malayi hypothetical protein 0.0014 0.0003 0.0003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.012 0.012
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0083 0.0083
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0296 0.3711
Loa Loa (eye worm) hypothetical protein 0.0242 0.114 0.114
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0727 0.0727
Toxoplasma gondii histone lysine methyltransferase SET1 0.0225 0.1057 1
Trypanosoma brucei glucosidase, putative 0.0035 0.0108 0.1347
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0054 0.0198 0.0198
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0003 0.0003
Loa Loa (eye worm) inositol-1 0.0073 0.0296 0.0296
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.015 0.0682 0.6446
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0108 0.0473 1
Onchocerca volvulus 0.0035 0.0107 0.0441
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0003 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.025 0.025
Brugia malayi ecdysone receptor 0.0014 0.0003 0.0003
Schistosoma mansoni lipoxygenase 0.0171 0.0784 0.0784
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0385 0.0385
Schistosoma mansoni hypothetical protein 0.0174 0.0799 0.0799
Schistosoma mansoni lamin 0.0054 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0035 0.0107 0.0107
Toxoplasma gondii hypothetical protein 0.0038 0.012 0.1137
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0083 0.0083
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0108 0.1017
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0083 0.0083
Brugia malayi tailless protein 0.0014 0.0003 0.0003
Schistosoma mansoni thyroid hormone receptor 0.003 0.0083 0.0083
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0108 0.0108
Onchocerca volvulus 0.0174 0.0799 0.3356
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0225 0.1058 1
Schistosoma mansoni sterol O-acyltransferase 1 0.0174 0.0799 0.0799
Echinococcus multilocularis Polycystic kidney disease protein 0.0039 0.0126 0.0126
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0174 0.0799 0.0799
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0083 0.0083
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0107 0.0107
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0003 0.0003
Echinococcus granulosus neuropeptide receptor A26 0.0471 0.2286 0.2286
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.0727 0.0727
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.025 0.025
Brugia malayi Pre-SET motif family protein 0.043 0.208 0.208
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0296 0.3711
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0083 0.0083
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0108 0.0447
Schistosoma mansoni alpha-glucosidase 0.0137 0.0616 0.0616
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.018 0.018
Onchocerca volvulus 0.0038 0.012 0.0495
Echinococcus multilocularis zinc finger protein 0.184 0.9132 0.9132
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0021 0.0038 0.0553
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.0043 0.0535
Brugia malayi nuclear hormone receptor 0.0014 0.0003 0.0003
Loa Loa (eye worm) norepinephrine transporter 0.0223 0.1046 0.1046
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.018 0.1703
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0174 0.0799 0.0799
Onchocerca volvulus 0.0092 0.0391 0.1638
Echinococcus multilocularis muscleblind protein 1 0.0451 0.2188 0.2188
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0038 0.012 0.012
Brugia malayi nuclear receptor NHR-88 0.003 0.0083 0.0083
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0385 0.0385
Trichomonas vaginalis conserved hypothetical protein 0.0174 0.0799 0.3359
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0083 0.0083
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0174 0.0799 0.0799
Onchocerca volvulus 0.0038 0.012 0.0495
Brugia malayi nuclear receptor NHR-88 0.0014 0.0003 0.0003
Echinococcus multilocularis sodium and chloride dependent glycine 0.0038 0.012 0.012
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0083 0.0083
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0003 0.0003
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0107 0.0107
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0174 0.0799 0.0799
Loa Loa (eye worm) cytochrome P450 family protein 0.0051 0.0186 0.0186
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0108 0.0473 0.0473
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0108 0.0447
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0062 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0108 0.0473 0.1986
Trichomonas vaginalis CMGC family protein kinase 0.005 0.018 0.0753
Onchocerca volvulus 0.0223 0.1046 0.4398
Echinococcus granulosus ornithine aminotransferase 0.0021 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0038 0.012 0.012
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0083 0.0083
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0139 0.1314
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0171 0.0784 0.0784
Schistosoma mansoni zinc finger protein 0.0014 0.0003 0.0003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0385 0.0385
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0083 0.0083
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0108 0.1094
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0108 0.1094
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0083 0.0083
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0108 0.1347
Mycobacterium ulcerans L-lysine aminotransferase 0.0021 0.0038 0.0553
Entamoeba histolytica hypothetical protein 0.0107 0.0466 0.5707
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0038 0.012 0.012
Echinococcus granulosus neuropeptide s receptor 0.0471 0.2286 0.2286
Loa Loa (eye worm) MBOAT family protein 0.0174 0.0799 0.0799
Brugia malayi MBOAT family protein 0.0174 0.0799 0.0799
Brugia malayi beta-lactamase family protein 0.0035 0.0107 0.0107
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0107 0.1091
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.043 0.208 0.208
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0023 0.0215
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0174 0.0799 0.0799
Echinococcus granulosus sodium and chloride dependent glycine 0.0038 0.012 0.012
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0107 0.0107
Mycobacterium tuberculosis Conserved protein 0.0035 0.0107 0.1015
Brugia malayi Doublecortin family protein 0.0039 0.0126 0.0126
Brugia malayi CXXC zinc finger family protein 0.0116 0.051 0.051
Schistosoma mansoni sodium/chloride dependent transporter 0.0038 0.012 0.012
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.018 0.2254
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0031 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0035 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0011
Loa Loa (eye worm) CXXC zinc finger family protein 0.0116 0.051 0.051
Trypanosoma cruzi glycerol uptake protein, putative 0.0174 0.0799 1
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0021 0.0038 0.0038
Mycobacterium ulcerans beta-lactamase 0.0035 0.0107 0.1574
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0296 0.3711
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0062 0.0256
Onchocerca volvulus 0.0038 0.012 0.0495
Schistosoma mansoni lamin 0.0054 0.0203 0.0203
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0062 0.0256
Loa Loa (eye worm) hypothetical protein 0.0035 0.0107 0.0107
Brugia malayi conserved hypotetical protein 0.0014 0.0003 0.0003
Schistosoma mansoni zinc finger protein 0.2014 1 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0038 0.012 0.012
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0062 0.0062
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0038 0.012 0.1137
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0108 0.1347
Leishmania major glycerol uptake protein, putative 0.0174 0.0799 1
Brugia malayi beta-lactamase 0.0035 0.0107 0.0107
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0174 0.0799 0.7554
Onchocerca volvulus 0.0035 0.0107 0.0441
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.0296 0.1243
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0107 0.0107
Schistosoma mansoni rab6-interacting 0.0039 0.0126 0.0126
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0174 0.0799 0.0799
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0038 0.012 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0223 0.1046 0.1046
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0003 0.0003
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.0618 0.0618
Echinococcus granulosus Polycystic kidney disease protein 0.0039 0.0126 0.0126
Trypanosoma brucei cytochrome P450, putative 0.0022 0.0043 0.0535
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0177 0.0177
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0083 0.0083
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0073 0.0296 0.3527
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0062 0.0256
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.0296 0.1243
Schistosoma mansoni nuclear receptor 0.0014 0.0003 0.0003
Brugia malayi ecdysteroid receptor 0.003 0.0083 0.0083
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0083 0.0083
Schistosoma mansoni transcription factor LCR-F1 0.0107 0.0466 0.0466
Echinococcus granulosus survival motor neuron protein 1 0.0242 0.114 0.114
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0126 0.0126
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0062 0.0256
Echinococcus multilocularis lamin dm0 0.0054 0.0203 0.0203
Leishmania major glycerol uptake protein, putative 0.0174 0.0799 1
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0038 0.012 0.012
Brugia malayi intermediate filament protein 0.0054 0.0203 0.0203
Loa Loa (eye worm) MBOAT family protein 0.0174 0.0799 0.0799
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0234 0.3434
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0108 0.0447
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0021 0.0038 0.0553
Schistosoma mansoni rab6-interacting 0.0039 0.0126 0.0126
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.0727 0.0727
Onchocerca volvulus 0.0064 0.025 0.1043
Plasmodium falciparum amino acid transporter, putative 0.0038 0.012 0.1257
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0073 0.0296 0.2803
Schistosoma mansoni serine/threonine protein kinase 0.005 0.018 0.018
Brugia malayi Hhat protein 0.0174 0.0799 0.0799
Brugia malayi Cytochrome P450 family protein 0.0022 0.0043 0.0043
Echinococcus granulosus serotonin transporter 0.0223 0.1046 0.1046
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0174 0.0799 0.3359
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0296 0.3711
Trypanosoma cruzi glycerol uptake protein, putative 0.0174 0.0799 1
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0011
Schistosoma mansoni sodium-dependent amino acid transporter 0.0038 0.012 0.012
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0038 0.012 0.012
Schistosoma mansoni thyroid hormone receptor 0.003 0.0083 0.0083
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0108 0.0473 0.5801
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0083 0.0083
Echinococcus granulosus o acyltransferase membrane bound domain 0.0174 0.0799 0.0799
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.003 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0174 0.0799 0.0799
Schistosoma mansoni inositol monophosphatase 0.0073 0.0296 0.0296
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0107 0.1015
Entamoeba histolytica hypothetical protein, conserved 0.0174 0.0799 1
Loa Loa (eye worm) hypothetical protein 0.0223 0.1046 0.1046
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0083 0.0083
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0107 0.0466 0.0466
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0062 0.0256
Loa Loa (eye worm) hypothetical protein 0.0039 0.0126 0.0126
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0083 0.0083
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0107 0.0466 0.0466
Trypanosoma cruzi GUP1, putative 0.0174 0.0799 1
Brugia malayi hypothetical protein 0.0016 0.0011 0.0011
Brugia malayi MBOAT family protein 0.0174 0.0799 0.0799
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0023 0.0023
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0003 0.0003
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0003 0.0003
Mycobacterium tuberculosis Conserved protein 0.0035 0.0107 0.1015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0083 0.0083
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0083 0.0083
Mycobacterium tuberculosis Probable aminotransferase 0.015 0.0682 0.6446
Echinococcus granulosus cpg binding protein 0.0122 0.0543 0.0543
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0139 0.1498
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0021 0.0038 0.0553
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0108 0.0108
Onchocerca volvulus 0.0049 0.0177 0.0737
Mycobacterium leprae Probable lipase LipE 0.0035 0.0107 0.1574
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0083 0.0083
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0108 0.0473 0.0473
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0107 0.1344
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0083 0.0083
Schistosoma mansoni cpg binding protein 0.0122 0.0543 0.0543
Trichomonas vaginalis inositol monophosphatase, putative 0.0073 0.0296 0.1243
Loa Loa (eye worm) DR-78 0.0014 0.0003 0.0003
Trichomonas vaginalis porcupine, putative 0.0174 0.0799 0.3359
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0174 0.0799 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0108 0.0447
Loa Loa (eye worm) hypothetical protein 0.0025 0.0057 0.0057
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0062 0.0256
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0107 0.1015
Toxoplasma gondii hypothetical protein 0.0038 0.012 0.1137
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0073 0.0296 1
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0062 0.0062
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0174 0.0799 0.0799
Echinococcus granulosus o acyltransferase membrane bound domain 0.0174 0.0799 0.0799
Echinococcus multilocularis neuropeptide receptor A26 0.0471 0.2286 0.2286
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Plasmodium vivax SET domain protein, putative 0.0064 0.025 0.2929
Loa Loa (eye worm) hhat protein 0.0174 0.0799 0.0799
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0174 0.0799 0.0799
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0234 0.0234
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.012 0.012
Loa Loa (eye worm) doublecortin family protein 0.0039 0.0126 0.0126
Schistosoma mansoni intermediate filament proteins 0.0054 0.0203 0.0203
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0083 0.0083
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0107 0.1344
Loa Loa (eye worm) acetyltransferase 0.0141 0.0638 0.0638
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0174 0.0799 0.0799
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0083 0.0083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0108 0.0473 0.1986
Brugia malayi follicle stimulating hormone receptor 0.0467 0.2266 0.2266
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0035 0.0107 0.0107
Trypanosoma brucei glycerol uptake protein, putative 0.0174 0.0799 1
Mycobacterium ulcerans hypothetical protein 0.015 0.0682 1
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0065 0.0258 0.3784
Schistosoma mansoni sodium/chloride dependent transporter 0.0223 0.1046 0.1046
Loa Loa (eye worm) hypothetical protein 0.0039 0.0126 0.0126
Schistosoma mansoni hypothetical protein 0.1237 0.6115 0.6115
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0108 0.0447
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0077 0.0077
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0107 0.1574
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0174 0.0799 0.0799
Leishmania major glycerol uptake protein, putative 0.0174 0.0799 1
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.018 0.018
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0108 0.0473 0.592
Loa Loa (eye worm) hypothetical protein 0.0174 0.0799 0.0799
Treponema pallidum alginate O-acetylation protein (algI) 0.0174 0.0799 0.7583
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0107 0.0446
Echinococcus multilocularis inositol monophosphatase 1 0.0073 0.0296 0.0296
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0083 0.0083
Echinococcus granulosus o acyltransferase membrane bound domain 0.0174 0.0799 0.0799
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0234 0.2215
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0062 0.0256
Echinococcus multilocularis muscleblind protein 0.0451 0.2188 0.2188
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0174 0.0799 0.0799
Brugia malayi MH2 domain containing protein 0.0117 0.0514 0.0514
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0062 0.0256
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0107 0.0466 0.5707
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0062
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0126 0.0126
Schistosoma mansoni alpha-glucosidase 0.0137 0.0616 0.0616
Entamoeba histolytica vacuolar protein sorting 26 0.0174 0.0799 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0139 0.0579
Echinococcus multilocularis ornithine aminotransferase 0.0021 0.0038 0.0038
Brugia malayi MBOAT family protein 0.0174 0.0799 0.0799
Onchocerca volvulus 0.0489 0.2375 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0057 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0083 0.0083
Loa Loa (eye worm) beta-lactamase 0.0035 0.0107 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0062 0.0256
Echinococcus granulosus lamin 0.0054 0.0203 0.0203
Brugia malayi hypothetical protein 0.0125 0.0557 0.0557
Echinococcus granulosus RUN 0.0039 0.0126 0.0126
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0003 0.0003
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0467 0.2266 0.2266
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0073 0.0296 0.4345
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0234 0.3434
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0385 0.0385
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0108 0.0447
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0174 0.0799 0.0799
Loa Loa (eye worm) hypothetical protein 0.0174 0.0799 0.0799
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0108 0.0473 0.0473
Brugia malayi Cytochrome P450 family protein 0.0022 0.0043 0.0043
Brugia malayi nuclear receptor NHR-67 0.0014 0.0003 0.0003
Echinococcus multilocularis Aminotransferase class III 0.0021 0.0038 0.0038
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0003 0.0003
Mycobacterium ulcerans acetylornithine aminotransferase 0.0021 0.0038 0.0553
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0021 0.0038 0.0553
Loa Loa (eye worm) hypothetical protein 0.0064 0.025 0.025
Leishmania major glycerol uptake protein, putative 0.0174 0.0799 1
Plasmodium vivax hypothetical protein, conserved 0.0038 0.012 0.1257
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0038 0.012 0.012
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0174 0.0799 0.0799
Brugia malayi steroid hormone receptor 0.003 0.0083 0.0083
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0174 0.0799 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0083 0.0083
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0083 0.0083

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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