Detailed information for compound 646438

Basic information

Technical information
  • TDR Targets ID: 646438
  • Name: N-(2-fluoro-5-nitrophenyl)-2,2-di(phenyl)acet amide
  • MW: 350.343 | Formula: C20H15FN2O3
  • H donors: 1 H acceptors: 3 LogP: 4.32 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1NC(=O)C(c1ccccc1)c1ccccc1)[N+](=O)[O-]
  • InChi: 1S/C20H15FN2O3/c21-17-12-11-16(23(25)26)13-18(17)22-20(24)19(14-7-3-1-4-8-14)15-9-5-2-6-10-15/h1-13,19H,(H,22,24)
  • InChiKey: QZONTYMFLSRFHT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2-fluoro-5-nitro-phenyl)-2,2-di(phenyl)acetamide
  • N-(2-fluoro-5-nitro-phenyl)-2,2-di(phenyl)ethanamide
  • Oprea1_489529
  • ARONIS021183
  • Oprea1_558710
  • ST055108
  • BIM-0011260.P001
  • AN-329/07140032
  • ZINC00668142
  • CBMicro_011377

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis mothers against decapentaplegic 2 0.0017 0.0076 0.0076
Echinococcus granulosus TGF beta signal transducer SmadC 0.0039 0.0255 0.0442
Trypanosoma brucei DNA polymerase eta, putative 0.0015 0.0057 0.0159
Schistosoma mansoni glutamate synthase 0.001 0.0019 0.0033
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0169 0.1354 0.4754
Schistosoma mansoni terminal deoxycytidyl transferase 0.0015 0.0057 0.01
Schistosoma mansoni cell adhesion molecule 0.001 0.0015 0.0026
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.001 0.0019 0.0023
Echinococcus multilocularis muscleblind protein 0.0143 0.1135 0.1135
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.004 0.0262 0.0455
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.001 0.0019 0.007
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0015 0.0026
Echinococcus granulosus RUN 0.0021 0.0107 0.0186
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0165 0.0287
Loa Loa (eye worm) hypothetical protein 0.005 0.0353 0.0738
Echinococcus granulosus carbonic anhydrase II 0.0136 0.1069 0.1855
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.026 0.2114 0.6282
Loa Loa (eye worm) TAR-binding protein 0.0109 0.0845 0.1788
Toxoplasma gondii LsmAD domain-containing protein 0.0039 0.0261 0.1255
Brugia malayi hypoxia-induced factor 1 0.0152 0.1203 0.2544
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0345 0.2827 0.2827
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0019 0.007
Loa Loa (eye worm) hypothetical protein 0.0038 0.0252 0.0522
Brugia malayi Pre-SET motif family protein 0.0203 0.1634 0.3467
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0015 0.0057 0.0057
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0046 0.0317 0.1061
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0136 0.1069 0.4302
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.001 0.0019 0.007
Trichomonas vaginalis esterase, putative 0.0038 0.0252 0.0832
Brugia malayi PAS domain containing protein 0.0049 0.0342 0.0702
Loa Loa (eye worm) carbonic anhydrase 3 0.0136 0.1069 0.2267
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0262 0.1052
Echinococcus multilocularis carbonic anhydrase 0.005 0.0353 0.0353
Trichomonas vaginalis set domain proteins, putative 0.0231 0.1868 0.6588
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0079 0.0214
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0038 0.0145
Loa Loa (eye worm) hypothetical protein 0.0018 0.0079 0.0151
Brugia malayi latrophilin 2 splice variant baaae 0.0161 0.1284 0.2719
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0093 0.0708 0.2068
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0124 0.0968 0.3379
Brugia malayi Cytochrome P450 family protein 0.0017 0.0072 0.0125
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0114 0.0888 0.2606
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0262 0.1052
Brugia malayi hypothetical protein 0.0039 0.0261 0.0528
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0075 0.0557 0.0557
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0105 0.0812 0.2825
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0017 0.0072 0.016
Leishmania major carbonic anhydrase-like protein 0.0136 0.1069 0.4302
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0169 0.1354 0.235
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0129 0.033
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Trypanosoma cruzi protein farnesyltransferase, putative 0.0169 0.1354 0.545
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0129 0.0392
Plasmodium falciparum glutathione reductase 0.004 0.0262 0.0868
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0107 0.0314
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0129 0.033
Loa Loa (eye worm) hypothetical protein 0.0038 0.0252 0.0522
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0252 0.1011
Schistosoma mansoni rab6-interacting 0.0021 0.0107 0.0186
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0252 0.0701
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0136 0.1069 0.1855
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0252 0.0511
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.001 0.0019 0.0011
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.029 0.1161
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.0686 0.1449
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0105 0.0812 0.3267
Trypanosoma brucei DNA polymerase IV, putative 0.0015 0.0057 0.0159
Leishmania major protein kinase, putative 0.0013 0.0038 0.0145
Plasmodium vivax SET domain protein, putative 0.003 0.018 0.0573
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0252 0.0701
Trypanosoma cruzi lanosterol synthase, putative 0.0093 0.0708 0.2849
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0368 0.1477
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.001 0.0019 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.001 0.0019 0.007
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0076 0.0144
Trypanosoma brucei PAB1-binding protein , putative 0.0039 0.0261 0.0984
Schistosoma mansoni hypothetical protein 0.001 0.0019 0.0033
Mycobacterium ulcerans hypothetical protein 0.0024 0.0129 0.033
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0261 0.0453
Entamoeba histolytica hypothetical protein 0.0117 0.091 0.3175
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.004 0.0262 0.1052
Treponema pallidum licC protein (licC) 0.0075 0.0558 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0241 0.0667
Onchocerca volvulus 0.003 0.018 0.0809
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0039 0.0255 0.0255
Brugia malayi glutathione reductase 0.0114 0.0888 0.187
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.005 0.0353 0.0726
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0015 0.0057 0.0105
Plasmodium falciparum carbonic anhydrase 0.005 0.0353 0.1192
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0105 0.0812 0.1718
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0241 0.0793
Loa Loa (eye worm) Smad1 0.0039 0.0255 0.0527
Schistosoma mansoni ap endonuclease 0.0037 0.0241 0.0419
Echinococcus multilocularis geminin 0.0663 0.5495 0.5495
Brugia malayi Cytochrome P450 family protein 0.0028 0.0164 0.0322
Mycobacterium tuberculosis Conserved protein 0.0038 0.0252 0.0701
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Onchocerca volvulus 0.0021 0.0107 0.0466
Brugia malayi mbt repeat family protein 0.0046 0.0315 0.0645
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.001 0.0019 0.0033
Mycobacterium ulcerans hypothetical protein 0.016 0.1275 0.3766
Loa Loa (eye worm) hypothetical protein 0.005 0.0353 0.0738
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0148 0.0529
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0169 0.1354 0.2876
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0038 0.0145
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0235 0.0648
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0079 0.2462
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0169 0.1354 0.4754
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0686 0.0686
Brugia malayi Calcitonin receptor-like protein seb-1 0.0236 0.1911 0.406
Onchocerca volvulus 0.0038 0.0252 0.1152
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.004 0.0262 0.0868
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0128 0.039
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0046 0.0317 0.1061
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0046 0.0317 0.1061
Schistosoma mansoni Smad4 0.0039 0.0255 0.0442
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0046 0.0317 0.1547
Loa Loa (eye worm) hypothetical protein 0.0143 0.1135 0.2408
Onchocerca volvulus 0.0256 0.2079 0.9764
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.004 0.0262 0.0868
Schistosoma mansoni cpg binding protein 0.0031 0.0187 0.0325
Plasmodium falciparum thioredoxin reductase 0.0114 0.0888 0.3095
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0345 0.2827 1
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0408 0.3354 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0686 0.0686
Mycobacterium tuberculosis Conserved hypothetical protein 0.016 0.1275 0.3766
Echinococcus multilocularis hemicentin 1 0.001 0.0015 0.0015
Echinococcus multilocularis roundabout 2 0.001 0.0015 0.0015
Echinococcus granulosus Smad4 0.0039 0.0255 0.0442
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0261 0.1045
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0038 0.0038
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0071 0.0156
Brugia malayi MH2 domain containing protein 0.0039 0.0255 0.0516
Brugia malayi Flap endonuclease-1 0.0026 0.0148 0.0288
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0236 0.1911 0.4067
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0046 0.0317 0.0648
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0038 0.0145
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0105 0.0812 0.0812
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0686 0.1191
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.005 0.0353 0.0726
Brugia malayi MH2 domain containing protein 0.0039 0.0255 0.0516
Trypanosoma cruzi trypanothione reductase, putative 0.0114 0.0888 0.3572
Schistosoma mansoni cpg binding protein 0.0031 0.0187 0.0325
Onchocerca volvulus 0.0036 0.0235 0.107
Schistosoma mansoni cpg binding protein 0.0029 0.0173 0.0301
Loa Loa (eye worm) hypothetical protein 0.0164 0.131 0.2782
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0015 0.0055 0.0223
Schistosoma mansoni hypothetical protein 0.0117 0.091 0.158
Schistosoma mansoni hypothetical protein 0.0412 0.3386 0.5878
Schistosoma mansoni hypothetical protein 0.0286 0.2331 0.4046
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.001 0.0018 0.0032
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0261 0.1256
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0107 0.0186
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.018 0.018
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0105 0.0812 0.2825
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0017
Giardia lamblia Prenyltransferase 0.0169 0.1354 0.4754
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0226 0.0622
Brugia malayi MH1 domain containing protein 0.0039 0.0255 0.0516
Schistosoma mansoni hypothetical protein 0.0075 0.0557 0.0967
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0241 0.0793
Schistosoma mansoni nephrin 0.001 0.0015 0.0026
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0084 0.0633 0.1099
Schistosoma mansoni inositol monophosphatase 0.0039 0.0261 0.0453
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0128 0.0328
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0105 0.0812 0.3222
Entamoeba histolytica hypothetical protein 0.0117 0.091 0.3175
Mycobacterium tuberculosis Probable reductase 0.026 0.2114 0.6282
Schistosoma mansoni glutamate synthase 0.001 0.0019 0.0033
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0304 0.2482 1
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0148 0.0592
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.001 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0252 0.0522
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0315 0.0547
Brugia malayi RNA recognition motif domain containing protein 0.0109 0.0845 0.1778
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.004 0.0262 0.073
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0128 0.0328
Loa Loa (eye worm) hypothetical protein 0.0345 0.2827 0.6024
Loa Loa (eye worm) hypothetical protein 0.005 0.0353 0.0738
Echinococcus granulosus roundabout 2 0.001 0.0015 0.0026
Leishmania major DNA polymerase kappa, putative 0.0015 0.0057 0.0225
Echinococcus granulosus tyrosine protein kinase otk 0.001 0.0015 0.0026
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Trypanosoma brucei NADH dehydrogenase 0.001 0.0019 0.0003
Onchocerca volvulus 0.0021 0.0107 0.0466
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.001 0.0019 0.0019
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0241 0.0793
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Echinococcus granulosus sulfide:quinone oxidoreductase 0.001 0.0019 0.0033
Loa Loa (eye worm) hypothetical protein 0.0021 0.0107 0.0211
Loa Loa (eye worm) hypothetical protein 0.0038 0.0252 0.0522
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0169 0.1354 0.4754
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0289 0.2357 0.7013
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.004 0.0262 0.1052
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.018 0.0312
Toxoplasma gondii exonuclease III APE 0.0037 0.0241 0.1155
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0019 0.007
Loa Loa (eye worm) transcription factor SMAD2 0.0567 0.4687 1
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0107 0.0211
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0261 0.0862
Echinococcus granulosus tar DNA binding protein 0.0109 0.0845 0.1466
Brugia malayi Pre-SET motif family protein 0.003 0.018 0.0355
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0038 0.0067
Schistosoma mansoni hypothetical protein 0.0075 0.0557 0.0967
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0148 0.0672
Entamoeba histolytica hypothetical protein 0.0117 0.091 0.3175
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0148 0.0461
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0235 0.0473
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0245 0.1986 0.5898
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0345 0.2827 1
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0107 0.0314
Mycobacterium ulcerans hypothetical protein 0.0075 0.0558 0.1618
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0252 0.0701
Brugia malayi beta-lactamase 0.0038 0.0252 0.0511
Loa Loa (eye worm) hypothetical protein 0.001 0.0019 0.0023
Brugia malayi Smad1 0.0039 0.0255 0.0516
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0252 0.0252
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0038 0.0067
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0144 0.1138 0.4546
Plasmodium vivax glutathione reductase, putative 0.0114 0.0888 0.3095
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0105 0.0812 0.2825
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0013 0.0038 0.0771
Loa Loa (eye worm) hypothetical protein 0.0046 0.0315 0.0657
Plasmodium vivax ataxin-2 like protein, putative 0.0039 0.0261 0.0861
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.018 0.0312
Schistosoma mansoni hypothetical protein 0.0161 0.1284 0.223
Loa Loa (eye worm) hypothetical protein 0.0038 0.0252 0.0522
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.001 0.0015 0.0015
Brugia malayi hypothetical protein 0.0117 0.091 0.1918
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.029 0.1102
Loa Loa (eye worm) histone methyltransferase 0.001 0.0015 0.0014
Trypanosoma brucei carbonic anhydrase-like protein 0.0136 0.1069 0.4264
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0315 0.0657
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0038 0.0067
Giardia lamblia NADH oxidase lateral transfer candidate 0.004 0.0262 0.0868
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0072 0.0285
Echinococcus granulosus basement membrane specific heparan sulfate 0.001 0.0018 0.0032
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.001 0.0019 0.0033
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0128 0.0569
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0105 0.0812 0.1708
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0107 0.0107
Brugia malayi Cytochrome P450 family protein 0.0017 0.0072 0.0125
Brugia malayi mothers against decapentaplegic homolog 3 0.0017 0.0076 0.0132
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0252 0.0832
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.1634 0.3475
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0304 0.2482 1
Schistosoma mansoni smad1 5 8 and 0.0039 0.0255 0.0442
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0105 0.0812 0.0812
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.024 0.1945 0.6861
Brugia malayi Thioredoxin reductase 0.0114 0.0888 0.187
Trypanosoma brucei cytochrome P450, putative 0.0017 0.0072 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0038 0.0067
Onchocerca volvulus 0.0011 0.002 0.0057
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0015 0.0057 0.0225
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0173 0.0353
Echinococcus multilocularis carbonic anhydrase II 0.0136 0.1069 0.1069
Echinococcus granulosus dnaJ subfamily B 0.0412 0.3386 0.5878
Mycobacterium tuberculosis Conserved hypothetical protein 0.0075 0.0558 0.1618
Brugia malayi ImpB/MucB/SamB family protein 0.0015 0.0057 0.0093
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0038 0.0063
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0252 0.0701
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0241 0.0667
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0129 0.033
Echinococcus granulosus mothers against decapentaplegic 6 0.0017 0.0076 0.0131
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0038 0.0145
Loa Loa (eye worm) MH2 domain-containing protein 0.0567 0.4687 1
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.001 0.0019 0.0003
Toxoplasma gondii thioredoxin reductase 0.0114 0.0888 0.4511
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0052 0.0368 0.0759
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0169 0.1354 0.4754
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0046 0.0317 0.055
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0084 0.0633 0.1325
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0148 0.0461
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0071 0.0156
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0038 0.0065
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.001 0.0015 0.0026
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0252 0.0951
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.005 0.0353 0.0738
Schistosoma mansoni single-minded 0.0049 0.0342 0.0593
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.001 0.0015 0.0015
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0399 0.1976
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0304 0.2482 1
Loa Loa (eye worm) glutathione reductase 0.0114 0.0888 0.188
Echinococcus granulosus dna polymerase kappa 0.0015 0.0057 0.01
Onchocerca volvulus 0.0247 0.2003 0.9406
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0262 0.1052
Mycobacterium tuberculosis Probable oxidoreductase 0.0289 0.2357 0.7013
Schistosoma mansoni rab6-interacting 0.0021 0.0107 0.0186
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0261 0.0985
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0148 0.0461
Echinococcus multilocularis dnaJ subfamily B 0.0412 0.3386 0.3386
Brugia malayi hypothetical protein 0.0025 0.0144 0.0278
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0315 0.0315
Onchocerca volvulus 0.0105 0.0812 0.3791
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0252 0.0438
Mycobacterium tuberculosis Conserved protein 0.0038 0.0252 0.0701
Echinococcus multilocularis tyrosine protein kinase otk 0.001 0.0015 0.0015
Brugia malayi MH1 domain containing protein 0.0039 0.0255 0.0516
Leishmania major lanosterol synthase, putative 0.0047 0.0322 0.1294
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0345 0.2827 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.004 0.0262 0.1052
Mycobacterium leprae Probable lipase LipE 0.0038 0.0252 0.0701
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0241 0.0906
Brugia malayi MH2 domain containing protein 0.0567 0.4687 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0075 0.0557 0.1174
Schistosoma mansoni hypothetical protein 0.0663 0.5495 0.9538
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0128 0.4496
Onchocerca volvulus 0.0084 0.0633 0.2948
Echinococcus granulosus smad 0.0039 0.0255 0.0442
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0029 0.0174 0.0344
Plasmodium falciparum geranylgeranyltransferase, putative 0.0046 0.0317 0.1061
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0129 0.0392
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Echinococcus multilocularis peroxidasin 0.001 0.0016 0.0016
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0015 0.0015
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.018 0.018
Loa Loa (eye worm) MH2 domain-containing protein 0.0039 0.0255 0.0527
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0345 0.2827 0.6019
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Schistosoma mansoni carbonic anhydrase-related 0.005 0.0353 0.0613
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0252 0.0701
Loa Loa (eye worm) hypothetical protein 0.0018 0.0079 0.0151
Onchocerca volvulus 0.0013 0.0038 0.0139
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0241 0.0419
Loa Loa (eye worm) hypothetical protein 0.0143 0.1135 0.2408
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.0686 0.1438
Trypanosoma brucei lanosterol synthase 0.0093 0.0708 0.2802
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0075 0.0558 0.1618
Brugia malayi hypothetical protein 0.0021 0.0107 0.0199
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0046 0.0317 0.1271
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0128 0.0447
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0169 0.1354 0.542
Leishmania major hypothetical protein, conserved 0.001 0.0019 0.007
Mycobacterium leprae Possible regulatory protein 0.0013 0.0038 0.0056
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0046 0.0317 0.055
Echinococcus granulosus thioredoxin glutathione reductase 0.0114 0.0888 0.1541
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0105 0.0812 0.3222
Schistosoma mansoni cell adhesion molecule 0.001 0.0015 0.0026
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.005 0.0353 0.0726
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.001 0.0015 0.0015
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0018 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0075 0.0557 0.1174
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0252 0.0701
Trypanosoma cruzi NADH dehydrogenase, putative 0.001 0.0019 0.007
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0261 0.0261
Leishmania major hypothetical protein, conserved 0.0039 0.0261 0.1044
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0107 0.0107
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0039 0.0255 0.0442
Schistosoma mansoni Smad4 0.0017 0.0076 0.0131
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0105 0.0812 0.3267
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0038 0.0145
Schistosoma mansoni transcription factor LCR-F1 0.0117 0.091 0.158
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0454 0.0789
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0046 0.0317 0.0317
Onchocerca volvulus 0.0024 0.0129 0.057
Loa Loa (eye worm) hypothetical protein 0.0046 0.0317 0.066
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0261 0.0726
Echinococcus multilocularis GPCR, family 2 0.0075 0.0557 0.0557
Schistosoma mansoni septate junction protein 0.001 0.0015 0.0026
Loa Loa (eye worm) hypothetical protein 0.0017 0.0076 0.0144
Schistosoma mansoni carbonic anhydrase-related 0.005 0.0353 0.0613
Loa Loa (eye worm) beta-lactamase 0.0038 0.0252 0.0522
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0046 0.0317 0.066
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0169 0.1354 0.4754
Brugia malayi Prion-like- 0.001 0.0015 0.0002
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0129 0.0246
Schistosoma mansoni microtubule-associated protein tau 0.0694 0.5761 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0015 0.0057 0.0225
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0038 0.0145
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0252 0.0701
Trichomonas vaginalis mercuric reductase, putative 0.004 0.0262 0.0868
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.004 0.0262 0.0992
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0072 0.0285
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0038 0.0067
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0241 0.0966
Mycobacterium ulcerans DNA polymerase IV 0.0015 0.0057 0.0116
Trypanosoma brucei DNA polymerase IV, putative 0.0015 0.0057 0.0159
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0128 0.039
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0136 0.1069 0.1855
Trypanosoma cruzi hypothetical protein, conserved 0.0105 0.0812 0.3267
Loa Loa (eye worm) hypoxia-induced factor 1 0.0152 0.1203 0.2553
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0241 0.0487
Brugia malayi beta-lactamase family protein 0.0038 0.0252 0.0511
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0169 0.1354 0.235
Brugia malayi TAR-binding protein 0.0109 0.0845 0.1778
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0046 0.0317 0.0317
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0071 0.0156
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.001 0.0019 0.007
Schistosoma mansoni cell adhesion molecule 0.001 0.0015 0.0026
Echinococcus multilocularis basement membrane specific heparan sulfate 0.001 0.0018 0.0018
Leishmania major hypothetical protein, conserved 0.001 0.0019 0.007
Brugia malayi MH1 domain containing protein 0.0021 0.011 0.0206
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0261 0.0726
Brugia malayi Doublecortin family protein 0.0021 0.0107 0.0199
Giardia lamblia Rab geranylgeranyltransferase 0.0105 0.0812 0.2825
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0128 0.0569
Schistosoma mansoni hypothetical protein 0.0018 0.0079 0.0137
Echinococcus multilocularis roundabout 2 0.001 0.0015 0.0015
Echinococcus multilocularis mothers against decapentaplegic 6 0.0017 0.0076 0.0076
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0315 0.0547
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Mycobacterium tuberculosis Probable dehydrogenase 0.026 0.2114 0.6282
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0129 0.033
Brugia malayi basement membrane proteoglycan precursor 0.001 0.0018 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0686 0.1191
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.001 0.0019 0.0019
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0345 0.2827 1
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.001 0.0018 0.0032
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.018 0.0312
Echinococcus multilocularis thioredoxin glutathione reductase 0.0114 0.0888 0.0888
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0052 0.0368 0.0368
Treponema pallidum NADH oxidase 0.004 0.0262 0.4515
Schistosoma mansoni ap endonuclease 0.0037 0.0241 0.0419
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0169 0.1354 0.4754
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0105 0.0812 0.141
Loa Loa (eye worm) hypothetical protein 0.0018 0.0079 0.0151
Trypanosoma cruzi lanosterol synthase, putative 0.0093 0.0708 0.2849
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0345 0.2827 0.6024
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0252 0.1011
Echinococcus multilocularis glutamate synthase 0.001 0.0019 0.0019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0015 0.0057 0.0225
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0072 0.0137
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0345 0.2827 1
Onchocerca volvulus Tyrosine kinase homolog 0.0262 0.2129 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0262 0.1052
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.001 0.0019 0.0003
Loa Loa (eye worm) programmed cell death 8 0.001 0.0019 0.0023
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.004 0.0262 0.0868
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.026 0.2114 0.6282
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.001 0.0019 0.007
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0052 0.0368 0.064
Echinococcus granulosus carbonic anhydrase 0.005 0.0353 0.0613
Onchocerca volvulus 0.0046 0.0315 0.1448
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.001 0.0019 0.0019
Onchocerca volvulus 0.0038 0.0252 0.1152
Echinococcus multilocularis microtubule associated protein 2 0.0694 0.5761 0.5761
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0188 0.1509 0.1509
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.001 0.0019 0.0019
Mycobacterium ulcerans hypothetical protein 0.0075 0.0558 0.1618
Trypanosoma brucei DNA polymerase IV, putative 0.0015 0.0057 0.0159
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0129 0.033
Mycobacterium ulcerans hypothetical protein 0.0038 0.0252 0.0701
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0169 0.1354 0.1354
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.029 0.1161
Toxoplasma gondii hypothetical protein 0.005 0.0353 0.1737
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0046 0.0317 0.1547
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0262 0.1052
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.001 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0261 0.1045
Echinococcus granulosus cpg binding protein 0.0031 0.0187 0.0325
Echinococcus granulosus carbonic anhydrase 0.005 0.0353 0.0613
Schistosoma mansoni tar DNA-binding protein 0.0109 0.0845 0.1466
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.004 0.0262 0.0532
Brugia malayi Inositol-1 0.0039 0.0261 0.0528
Echinococcus multilocularis dna polymerase kappa 0.0015 0.0057 0.0057
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0169 0.1354 0.4754
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0128 0.0511
Trypanosoma brucei unspecified product 0.0015 0.0057 0.0159
Loa Loa (eye worm) hypothetical protein 0.0046 0.0317 0.066
Echinococcus granulosus histone acetyltransferase MYST2 0.0052 0.0368 0.064
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0046 0.0317 0.1061
Plasmodium vivax geranylgeranyltransferase, putative 0.0046 0.0317 0.1061
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0129 0.033
Entamoeba histolytica hypothetical protein 0.0117 0.091 0.3175
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0075 0.0557 0.0967
Brugia malayi hypothetical protein 0.0247 0.2003 0.4256
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Echinococcus granulosus neuroglian 0.001 0.0015 0.0026
Schistosoma mansoni lipoxygenase 0.0088 0.0667 0.1158
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.004 0.0262 0.073
Schistosoma mansoni tar DNA-binding protein 0.0109 0.0845 0.1466
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0252 0.0832
Schistosoma mansoni tar DNA-binding protein 0.0109 0.0845 0.1466
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0252 0.0522
Schistosoma mansoni hypothetical protein 0.0021 0.0107 0.0186
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0235 0.0235
Trypanosoma brucei trypanothione reductase 0.0114 0.0888 0.3529
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0117 0.091 0.091
Schistosoma mansoni tar DNA-binding protein 0.0109 0.0845 0.1466
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0129 0.0246
Trypanosoma cruzi protein farnesyltransferase, putative 0.0169 0.1354 0.545
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0129 0.0513
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.001 0.0019 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0317 0.1271
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.001 0.0015 0.0026
Trichomonas vaginalis glutathione reductase, putative 0.004 0.0262 0.0868
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0241 0.0499
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0241 0.0966
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.018 0.0835
Schistosoma mansoni disulfide oxidoreductase 0.001 0.0019 0.0033
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.004 0.0262 0.1265
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0105 0.0812 0.3267
Giardia lamblia Rab geranylgeranyltransferase 0.0046 0.0317 0.1061
Schistosoma mansoni hypothetical protein 0.0075 0.0557 0.0967
Schistosoma mansoni roundabout 0.001 0.0015 0.0026
Schistosoma mansoni smad1 5 8 and 0.0039 0.0255 0.0442
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0252 0.0438
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0002
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0261 0.0862
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0252 0.0701
Entamoeba histolytica hypothetical protein 0.0024 0.0128 0.039
Leishmania major trypanothione reductase 0.0114 0.0888 0.3572
Brugia malayi Immunoglobulin I-set domain containing protein 0.0263 0.2139 0.4548
Schistosoma mansoni smad 0.0039 0.0255 0.0442
Schistosoma mansoni glutamate synthase 0.001 0.0019 0.0033
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0263 0.2139 0.4555
Brugia malayi MH2 domain containing protein 0.0017 0.0076 0.0132
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0009 0.0007 0.0013
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0236 0.1911 0.406
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.004 0.0262 0.0992
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Schistosoma mansoni smad 0.0017 0.0076 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0038 0.0067
Echinococcus granulosus L aminoadipate semialdehyde 0.0084 0.0633 0.1099
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0038 0.0065
Plasmodium falciparum ataxin-2 like protein, putative 0.0039 0.0261 0.0861
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0075 0.0557 0.0557
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.004 0.0262 0.073
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0345 0.2827 0.4906
Echinococcus granulosus muscleblind protein 0.0143 0.1135 0.197
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.001 0.0019 0.0033
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0686 0.1191
Plasmodium falciparum flap endonuclease 1 0.0026 0.0148 0.0461
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0075 0.0557 0.1163
Plasmodium falciparum glutathione reductase 0.0114 0.0888 0.3095
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0408 0.3354 1
Echinococcus multilocularis L aminoadipate semialdehyde 0.0084 0.0633 0.0633
Trypanosoma cruzi trypanothione reductase, putative 0.004 0.0262 0.1052
Mycobacterium tuberculosis Conserved hypothetical protein 0.0015 0.0057 0.0116
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0038 0.0067
Echinococcus granulosus contactin 0.001 0.0015 0.0026
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0148 0.03
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0015 0.0057 0.01
Loa Loa (eye worm) MBCTL1 0.0052 0.0368 0.077
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0038 0.0038
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0071 0.0156
Toxoplasma gondii NADPH-glutathione reductase 0.004 0.0262 0.1265
Mycobacterium ulcerans beta-lactamase 0.0038 0.0252 0.0701
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0252 0.0832
Loa Loa (eye worm) hypothetical protein 0.0161 0.1284 0.2728
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0029 0.0174 0.0344
Leishmania major farnesyltransferase beta subunit 0.0169 0.1354 0.545
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0289 0.2357 0.7013
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0252 0.0701
Trypanosoma cruzi PAB1-binding protein , putative 0.0039 0.0261 0.1044
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0136 0.1069 0.2267
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.004 0.0262 0.073
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.004 0.0262 0.0868
Schistosoma mansoni flap endonuclease-1 0.0023 0.0127 0.0221
Schistosoma mansoni Smad4 0.0017 0.0076 0.0131
Echinococcus multilocularis Smad4 0.0039 0.0255 0.0255
Entamoeba histolytica deoxycytidyl transferase, putative 0.0015 0.0057 0.0137
Echinococcus granulosus geminin 0.0663 0.5495 0.9538
Trypanosoma cruzi hypothetical protein, conserved 0.0105 0.0812 0.3267
Leishmania major dihydrolipoamide dehydrogenase, putative 0.004 0.0262 0.1052
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0686 0.1191
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0241 0.4124
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.001 0.0015 0.0015
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0164 0.0334
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.005 0.0353 0.0726
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0241 0.0793
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0169 0.1354 0.2867
Schistosoma mansoni hypothetical protein 0.005 0.0353 0.0613
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0105 0.0812 0.3267
Schistosoma mansoni inositol monophosphatase 0.0039 0.0261 0.0453
Echinococcus multilocularis roundabout 2 0.001 0.0015 0.0015
Echinococcus multilocularis tar DNA binding protein 0.0109 0.0845 0.0845
Schistosoma mansoni smad1 5 8 and 0.0039 0.0255 0.0442
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0129 0.0513
Plasmodium falciparum thioredoxin reductase 0.004 0.0262 0.0868
Loa Loa (eye worm) hypothetical protein 0.003 0.018 0.0367
Trypanosoma cruzi DNA polymerase kappa, putative 0.0015 0.0057 0.0225
Mycobacterium ulcerans lipase LipD 0.0038 0.0252 0.0701
Brugia malayi beta-lactamase family protein 0.0038 0.0252 0.0511
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0046 0.0317 0.1212
Schistosoma mansoni sulfide quinone reductase 0.001 0.0019 0.0033
Schistosoma mansoni polycystin 1-related 0.0021 0.0107 0.0186
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0038 0.0145
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0261 0.0862
Echinococcus granulosus hemicentin 1 0.001 0.0015 0.0026
Echinococcus granulosus mothers against decapentaplegic 5 0.0039 0.0255 0.0442
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0079 0.018
Loa Loa (eye worm) hypothetical protein 0.0084 0.0633 0.1336
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.004 0.0262 0.0992
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.004 0.0262 0.073
Loa Loa (eye worm) hypothetical protein 0.0039 0.0261 0.054
Echinococcus multilocularis carbonic anhydrase 0.005 0.0353 0.0353
Schistosoma mansoni neuroglian 0.001 0.0015 0.0026
Schistosoma mansoni tar DNA-binding protein 0.0109 0.0845 0.1466
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.001 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0247 0.2003 0.4263
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0126 0.0984 0.1709
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0315 0.0547
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0261 0.1045
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.001 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0024 0.0129 0.0258
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0226 0.0622
Toxoplasma gondii hypothetical protein 0.0105 0.0812 0.4118
Echinococcus granulosus low density lipoprotein receptor ldl 0.001 0.0018 0.0032
Loa Loa (eye worm) hypothetical protein 0.0052 0.0368 0.077
Schistosoma mansoni DNA polymerase eta 0.0015 0.0057 0.01
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0136 0.1069 0.2258
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0136 0.1069 0.2258
Brugia malayi MH1 domain containing protein 0.0021 0.011 0.0206
Plasmodium falciparum ataxin-2 like protein, putative 0.0039 0.0261 0.0861
Echinococcus granulosus glutamate synthase 0.001 0.0019 0.0033
Leishmania major hypothetical protein, conserved 0.0038 0.0252 0.1011
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0252 0.0832
Echinococcus multilocularis cpg binding protein 0.0031 0.0187 0.0187
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.004 0.0262 0.0455
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0129 0.0513
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0079 0.018
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0105 0.0812 0.141
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.001 0.0019 0.0033
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0129 0.033
Loa Loa (eye worm) thioredoxin reductase 0.0114 0.0888 0.188
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0148 0.0148
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.005 0.0353 0.0726
Echinococcus multilocularis carbonic anhydrase 0.005 0.0353 0.0353
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0241 0.0667
Toxoplasma gondii ABC1 family protein 0.0038 0.0252 0.1213
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0015 0.0057 0.0137
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0315 0.1448
Brugia malayi ImpB/MucB/SamB family protein 0.0015 0.0057 0.0093
Onchocerca volvulus 0.0038 0.0252 0.1152
Schistosoma mansoni myelin transcription factor 1 myt1 0.0052 0.0368 0.064
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0038 0.0067
Mycobacterium tuberculosis Putative ferredoxin reductase 0.026 0.2114 0.6282
Brugia malayi Peroxidasin 0.001 0.0016 0.0005
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.001 0.0019 0.0011
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0107 0.0107
Schistosoma mansoni loxhd1 0.0021 0.0107 0.0186
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0315 0.0315
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0117 0.091 0.158
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0128 0.0328
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0022
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0128 0.0328
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.026 0.2114 0.6282
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0038 0.0067
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0241 0.0793
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0315 0.0547
Loa Loa (eye worm) hypothetical protein 0.0038 0.0252 0.0522
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.001 0.0019 0.0011
Echinococcus granulosus microtubule associated protein 2 0.0694 0.5761 1
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.004 0.0262 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0038 0.0063
Brugia malayi hypothetical protein 0.0164 0.131 0.2773
Schistosoma mansoni hypothetical protein 0.0075 0.0557 0.0967
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0017 0.0076 0.0319
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.001 0.0019 0.0003
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0015 0.0057 0.0116
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0075 0.0557 0.0967
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0408 0.3354 1
Trypanosoma brucei hypothetical protein, conserved 0.001 0.0019 0.0003
Leishmania major DNA polymerase eta, putative 0.0015 0.0057 0.0225
Echinococcus multilocularis lachesin 0.001 0.0015 0.0015
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0109 0.0845 0.1788
Brugia malayi hypothetical protein 0.0021 0.0107 0.0199
Brugia malayi RNA binding protein 0.0109 0.0845 0.1778
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0686 0.1191
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0188 0.1509 0.2619
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.001 0.0019 0.007
Brugia malayi CXXC zinc finger family protein 0.0029 0.0173 0.0341
Echinococcus multilocularis muscleblind protein 1 0.0143 0.1135 0.1135
Trypanosoma brucei hypothetical protein, conserved 0.0105 0.0812 0.3222
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0169 0.1354 0.4754
Leishmania major hypothetical protein, conserved 0.001 0.0019 0.007
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0345 0.2827 0.4906
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.1138 0.4582
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0128 0.203
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0241 0.0793
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.001 0.0015 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0218
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.018 0.0312
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.001 0.0019 0.007
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0129 0.033
Echinococcus granulosus flap endonuclease 1 0.0026 0.0148 0.0257
Loa Loa (eye worm) inositol-1 0.0039 0.0261 0.054
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0261 0.0862
Echinococcus granulosus mothers against decapentaplegic 2 0.0017 0.0076 0.0131
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.012 0.0939 0.1629
Schistosoma mansoni titin 0.001 0.0015 0.0026
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.004 0.0262 0.0992
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0136 0.1069 0.4302
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0046 0.0317 0.055
Trypanosoma cruzi DNA polymerase eta, putative 0.0015 0.0057 0.0225
Schistosoma mansoni carbonic anhydrase-related 0.005 0.0353 0.0613
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Loa Loa (eye worm) hypothetical protein 0.0236 0.1911 0.4067
Leishmania major NADH dehydrogenase, putative 0.001 0.0019 0.007
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0315 0.0547
Toxoplasma gondii hypothetical protein 0.024 0.1945 1
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0046 0.0317 0.1061
Brugia malayi mbt repeat family protein 0.0046 0.0315 0.0645
Echinococcus granulosus dna polymerase eta 0.0015 0.0057 0.01
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.029 0.1161
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0038 0.0067
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0342 0.0593
Loa Loa (eye worm) hypothetical protein 0.0018 0.0079 0.0151
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0129 0.033
Loa Loa (eye worm) hypothetical protein 0.0021 0.0107 0.0211
Trypanosoma cruzi DNA polymerase kappa, putative 0.0015 0.0057 0.0225
Loa Loa (eye worm) nuclear factor I 0.0021 0.011 0.0218
Loa Loa (eye worm) hypothetical protein 0.0015 0.0057 0.0105
Mycobacterium tuberculosis Conserved hypothetical protein 0.0075 0.0558 0.1618
Onchocerca volvulus 0.001 0.0019 0.0051
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Onchocerca volvulus 0.0231 0.1868 0.8772
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0345 0.2827 1
Plasmodium vivax thioredoxin reductase, putative 0.0114 0.0888 0.3095
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0046 0.0317 0.1061
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0129 0.033
Leishmania major cytochrome p450-like protein 0.0017 0.0072 0.0285
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0046 0.0317 0.1061
Giardia lamblia Rab geranylgeranyltransferase 0.0345 0.2827 1
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0148 0.0592
Schistosoma mansoni carbonic anhydrase 0.005 0.0353 0.0613
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0107 0.0186
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0289 0.2357 0.7013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.018 0.0312
Echinococcus granulosus roundabout 2 0.001 0.0015 0.0026
Loa Loa (eye worm) MH1 domain-containing protein 0.0039 0.0255 0.0527
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0317 0.1271
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.1138 0.4582
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0252 0.0832
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0046 0.0317 0.055
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.001 0.0015 0.0015
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.026 0.2114 0.6282
Onchocerca volvulus 0.0029 0.0173 0.078
Echinococcus multilocularis RUN 0.0021 0.0107 0.0107
Leishmania major dihydrolipoamide dehydrogenase, putative 0.004 0.0262 0.1052
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0046 0.0317 0.0648
Loa Loa (eye worm) CYP4Cod1 0.0017 0.0072 0.0137
Schistosoma mansoni hypothetical protein 0.0663 0.5495 0.9538
Brugia malayi Muscleblind-like protein 0.0143 0.1135 0.2399
Echinococcus granulosus single minded 2 0.0036 0.0235 0.0408
Echinococcus granulosus lachesin 0.001 0.0015 0.0026
Mycobacterium ulcerans flavoprotein disulfide reductase 0.004 0.0262 0.073
Leishmania major protein kinase, putative 0.0013 0.0038 0.0145
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0262 0.1052
Mycobacterium ulcerans DNA polymerase IV 0.0015 0.0057 0.0116
Schistosoma mansoni tyrosine kinase 0.0012 0.0028 0.0049
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0169 0.1354 0.4754
Echinococcus multilocularis mothers against decapentaplegic 5 0.0039 0.0255 0.0255
Schistosoma mansoni lipoxygenase 0.0126 0.0984 0.1709
Loa Loa (eye worm) hypothetical protein 0.0024 0.0129 0.0258
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0129 0.033
Loa Loa (eye worm) RNA binding protein 0.0109 0.0845 0.1788
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.004 0.0262 0.0262
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.0408 0.3354 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0252 0.0438
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0129 0.0246
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.004 0.0262 0.1052
Leishmania major mitochondrial DNA polymerase beta 0.0304 0.2482 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0072 0.0137
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.001 0.0019 0.0003
Echinococcus granulosus GPCR family 2 0.0075 0.0557 0.0967
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0241 0.0241
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0075 0.0558 0.2801
Echinococcus multilocularis hemicentin 1 0.001 0.0015 0.0015
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0107 0.0186
Echinococcus multilocularis histone acetyltransferase MYST2 0.0052 0.0368 0.0368
Loa Loa (eye worm) hypothetical protein 0.0024 0.0129 0.0258
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0018 0.0079 0.0137
Echinococcus multilocularis contactin neuroglian septate junction protein 0.001 0.0015 0.0015
Schistosoma mansoni sulfide quinone reductase 0.001 0.0019 0.0033
Schistosoma mansoni septate junction protein 0.001 0.0015 0.0026
Brugia malayi glutamate synthase 0.001 0.0019 0.0011
Echinococcus multilocularis dna polymerase eta 0.0015 0.0057 0.0057
Trichomonas vaginalis DNA polymerase eta, putative 0.0015 0.0057 0.0137
Echinococcus granulosus carbonic anhydrase 0.005 0.0353 0.0613
Trypanosoma cruzi PAB1-binding protein , putative 0.0039 0.0261 0.1044
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.001 0.0018 0.0032
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0241 0.0966
Giardia lamblia DINP protein human, muc B family 0.0015 0.0057 0.0137
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0148 0.0461
Echinococcus multilocularis neuroglian 0.001 0.0015 0.0015
Echinococcus granulosus peroxidasin 0.001 0.0016 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0252 0.0832
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0105 0.0812 0.2825
Mycobacterium tuberculosis Conserved protein 0.0038 0.0252 0.0701
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0169 0.1354 0.6929
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0105 0.0812 0.3222
Toxoplasma gondii hypothetical protein 0.0049 0.0342 0.1679
Leishmania major geranylgeranyltransferase, putative 0.0046 0.0317 0.1271
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0038 0.0067
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0079 0.0214
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0076 0.0144
Brugia malayi Latrophilin receptor protein 2 0.0075 0.0557 0.1163
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0129 0.0392
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0126 0.0984 0.0984
Trypanosoma cruzi NADH dehydrogenase, putative 0.001 0.0019 0.007
Echinococcus granulosus roundabout 2 0.001 0.0015 0.0026
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0128 0.0328
Echinococcus multilocularis smad 0.0039 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0018 0.0079 0.0151
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0252 0.0701
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.001 0.0015 0.0015

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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