Detailed information for compound 646438

Basic information

Technical information
  • TDR Targets ID: 646438
  • Name: N-(2-fluoro-5-nitrophenyl)-2,2-di(phenyl)acet amide
  • MW: 350.343 | Formula: C20H15FN2O3
  • H donors: 1 H acceptors: 3 LogP: 4.32 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1NC(=O)C(c1ccccc1)c1ccccc1)[N+](=O)[O-]
  • InChi: 1S/C20H15FN2O3/c21-17-12-11-16(23(25)26)13-18(17)22-20(24)19(14-7-3-1-4-8-14)15-9-5-2-6-10-15/h1-13,19H,(H,22,24)
  • InChiKey: QZONTYMFLSRFHT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2-fluoro-5-nitro-phenyl)-2,2-di(phenyl)acetamide
  • N-(2-fluoro-5-nitro-phenyl)-2,2-di(phenyl)ethanamide
  • Oprea1_489529
  • ARONIS021183
  • Oprea1_558710
  • ST055108
  • BIM-0011260.P001
  • AN-329/07140032
  • ZINC00668142
  • CBMicro_011377

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0046 0.0317 0.0317
Echinococcus multilocularis roundabout 2 0.001 0.0015 0.0015
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.026 0.2114 0.6282
Brugia malayi mbt repeat family protein 0.0046 0.0315 0.0645
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0252 0.0438
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.005 0.0353 0.0726
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0235 0.0235
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0015 0.0057 0.0137
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0038 0.0067
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0136 0.1069 0.2258
Brugia malayi glutamate synthase 0.001 0.0019 0.0011
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0107 0.0211
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0017
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.001 0.0015 0.0026
Echinococcus granulosus L aminoadipate semialdehyde 0.0084 0.0633 0.1099
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0022
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0015 0.0057 0.0105
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0252 0.0832
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0241 0.0966
Loa Loa (eye worm) hypothetical protein 0.005 0.0353 0.0738
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0261 0.1045
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0342 0.0593
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0038 0.0065
Trichomonas vaginalis mercuric reductase, putative 0.004 0.0262 0.0868
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0317 0.1271
Schistosoma mansoni glutamate synthase 0.001 0.0019 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0019 0.007
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0148 0.0672
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0148 0.03
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0018 0.0079 0.0137
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0304 0.2482 1
Mycobacterium tuberculosis Conserved protein 0.0038 0.0252 0.0701
Leishmania major NADH dehydrogenase, putative 0.001 0.0019 0.007
Echinococcus granulosus mothers against decapentaplegic 6 0.0017 0.0076 0.0131
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.004 0.0262 0.1265
Mycobacterium tuberculosis Conserved protein 0.0038 0.0252 0.0701
Echinococcus granulosus contactin 0.001 0.0015 0.0026
Schistosoma mansoni tar DNA-binding protein 0.0109 0.0845 0.1466
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Onchocerca volvulus 0.0021 0.0107 0.0466
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0262 0.1052
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0129 0.033
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0076 0.0144
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0252 0.0438
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.004 0.0262 0.1052
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.004 0.0262 0.0532
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0019 0.007
Echinococcus granulosus hemicentin 1 0.001 0.0015 0.0026
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0345 0.2827 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.004 0.0262 0.0992
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0075 0.0557 0.0557
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.005 0.0353 0.0726
Loa Loa (eye worm) hypothetical protein 0.0046 0.0315 0.0657
Schistosoma mansoni hypothetical protein 0.0117 0.091 0.158
Trichomonas vaginalis esterase, putative 0.0038 0.0252 0.0832
Loa Loa (eye worm) hypothetical protein 0.0164 0.131 0.2782
Echinococcus multilocularis dnaJ subfamily B 0.0412 0.3386 0.3386
Leishmania major carbonic anhydrase-like protein 0.0136 0.1069 0.4302
Onchocerca volvulus 0.001 0.0019 0.0051
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0107 0.0314
Onchocerca volvulus Tyrosine kinase homolog 0.0262 0.2129 1
Brugia malayi Cytochrome P450 family protein 0.0017 0.0072 0.0125
Loa Loa (eye worm) hypothetical protein 0.0039 0.0261 0.054
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0262 0.1052
Brugia malayi beta-lactamase family protein 0.0038 0.0252 0.0511
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0039 0.0255 0.0255
Echinococcus granulosus RUN 0.0021 0.0107 0.0186
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0129 0.033
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0188 0.1509 0.1509
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.001 0.0019 0.0003
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0038 0.0038
Onchocerca volvulus 0.0021 0.0107 0.0466
Loa Loa (eye worm) Smad1 0.0039 0.0255 0.0527
Echinococcus granulosus basement membrane specific heparan sulfate 0.001 0.0018 0.0032
Loa Loa (eye worm) hypothetical protein 0.0024 0.0129 0.0258
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0261 0.0726
Toxoplasma gondii thioredoxin reductase 0.0114 0.0888 0.4511
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0129 0.0513
Trypanosoma cruzi lanosterol synthase, putative 0.0093 0.0708 0.2849
Brugia malayi Pre-SET motif family protein 0.003 0.018 0.0355
Brugia malayi Prion-like- 0.001 0.0015 0.0002
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0252 0.0522
Loa Loa (eye worm) MH2 domain-containing protein 0.0039 0.0255 0.0527
Onchocerca volvulus 0.0084 0.0633 0.2948
Loa Loa (eye worm) hypothetical protein 0.0046 0.0317 0.066
Loa Loa (eye worm) hypothetical protein 0.0038 0.0252 0.0522
Trichomonas vaginalis glutathione reductase, putative 0.004 0.0262 0.0868
Schistosoma mansoni tar DNA-binding protein 0.0109 0.0845 0.1466
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0105 0.0812 0.1718
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0128 0.039
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0105 0.0812 0.141
Schistosoma mansoni glutamate synthase 0.001 0.0019 0.0033
Loa Loa (eye worm) thioredoxin reductase 0.0114 0.0888 0.188
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.001 0.0018 0.0018
Echinococcus multilocularis thioredoxin glutathione reductase 0.0114 0.0888 0.0888
Loa Loa (eye worm) MBCTL1 0.0052 0.0368 0.077
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0241 0.0793
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0241 0.0419
Echinococcus granulosus lachesin 0.001 0.0015 0.0026
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.004 0.0262 0.073
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0241 0.0793
Brugia malayi RNA recognition motif domain containing protein 0.0109 0.0845 0.1778
Schistosoma mansoni DNA polymerase eta 0.0015 0.0057 0.01
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.012 0.0939 0.1629
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0129 0.033
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.018 0.018
Mycobacterium tuberculosis Putative ferredoxin reductase 0.026 0.2114 0.6282
Echinococcus granulosus flap endonuclease 1 0.0026 0.0148 0.0257
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0315 0.0547
Mycobacterium tuberculosis Conserved hypothetical protein 0.016 0.1275 0.3766
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.004 0.0262 0.0992
Echinococcus granulosus cpg binding protein 0.0031 0.0187 0.0325
Echinococcus granulosus roundabout 2 0.001 0.0015 0.0026
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.001 0.0019 0.0019
Trypanosoma brucei lanosterol synthase 0.0093 0.0708 0.2802
Loa Loa (eye worm) hypothetical protein 0.0018 0.0079 0.0151
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0079 0.018
Echinococcus multilocularis roundabout 2 0.001 0.0015 0.0015
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0105 0.0812 0.0812
Schistosoma mansoni glutamate synthase 0.001 0.0019 0.0033
Echinococcus granulosus mothers against decapentaplegic 5 0.0039 0.0255 0.0442
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0136 0.1069 0.1855
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0038 0.0145
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.018 0.0312
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0038 0.0067
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0029 0.0174 0.0344
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0241 0.0966
Brugia malayi mbt repeat family protein 0.0046 0.0315 0.0645
Plasmodium vivax thioredoxin reductase, putative 0.0114 0.0888 0.3095
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.0686 0.1449
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0046 0.0317 0.1061
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0052 0.0368 0.064
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0072 0.0285
Schistosoma mansoni Smad4 0.0017 0.0076 0.0131
Mycobacterium ulcerans hypothetical protein 0.0024 0.0129 0.033
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.001 0.0019 0.0003
Trypanosoma brucei unspecified product 0.0015 0.0057 0.0159
Onchocerca volvulus 0.0038 0.0252 0.1152
Entamoeba histolytica deoxycytidyl transferase, putative 0.0015 0.0057 0.0137
Echinococcus granulosus smad 0.0039 0.0255 0.0442
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0107 0.0107
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0046 0.0317 0.1061
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.026 0.2114 0.6282
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0345 0.2827 1
Loa Loa (eye worm) hypoxia-induced factor 1 0.0152 0.1203 0.2553
Trypanosoma brucei hypothetical protein, conserved 0.001 0.0019 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Plasmodium vivax ataxin-2 like protein, putative 0.0039 0.0261 0.0861
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0136 0.1069 0.4302
Echinococcus multilocularis microtubule associated protein 2 0.0694 0.5761 0.5761
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0252 0.1011
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.001 0.0019 0.0033
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.001 0.0015 0.0015
Echinococcus granulosus roundabout 2 0.001 0.0015 0.0026
Onchocerca volvulus 0.0038 0.0252 0.1152
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Onchocerca volvulus 0.0105 0.0812 0.3791
Trypanosoma brucei cytochrome P450, putative 0.0017 0.0072 0.022
Schistosoma mansoni rab6-interacting 0.0021 0.0107 0.0186
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.0686 0.1438
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0686 0.0686
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0079 0.0214
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.001 0.0019 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Echinococcus multilocularis dna polymerase eta 0.0015 0.0057 0.0057
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0071 0.0156
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0345 0.2827 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0129 0.0392
Giardia lamblia NADH oxidase lateral transfer candidate 0.004 0.0262 0.0868
Schistosoma mansoni cell adhesion molecule 0.001 0.0015 0.0026
Leishmania major protein kinase, putative 0.0013 0.0038 0.0145
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0038 0.0067
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0105 0.0812 0.3267
Echinococcus granulosus histone acetyltransferase MYST2 0.0052 0.0368 0.064
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0039 0.0255 0.0442
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0038 0.0038
Echinococcus multilocularis tyrosine protein kinase otk 0.001 0.0015 0.0015
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0128 0.0447
Brugia malayi Doublecortin family protein 0.0021 0.0107 0.0199
Leishmania major geranylgeranyltransferase, putative 0.0046 0.0317 0.1271
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0262 0.1052
Echinococcus granulosus neuroglian 0.001 0.0015 0.0026
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0226 0.0622
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0128 0.039
Echinococcus multilocularis carbonic anhydrase 0.005 0.0353 0.0353
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.004 0.0262 0.073
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0079 0.018
Brugia malayi MH1 domain containing protein 0.0021 0.011 0.0206
Leishmania major hypothetical protein, conserved 0.0038 0.0252 0.1011
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0261 0.0985
Brugia malayi MH1 domain containing protein 0.0021 0.011 0.0206
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0046 0.0317 0.055
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0261 0.0261
Schistosoma mansoni hypothetical protein 0.0018 0.0079 0.0137
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0079 0.2462
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.004 0.0262 0.0455
Mycobacterium leprae Possible regulatory protein 0.0013 0.0038 0.0056
Schistosoma mansoni cpg binding protein 0.0029 0.0173 0.0301
Schistosoma mansoni cpg binding protein 0.0031 0.0187 0.0325
Brugia malayi beta-lactamase family protein 0.0038 0.0252 0.0511
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.029 0.1161
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0173 0.0353
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0226 0.0622
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0252 0.0438
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.004 0.0262 0.1052
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0241 0.0793
Giardia lamblia DINP protein human, muc B family 0.0015 0.0057 0.0137
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.001 0.0019 0.0003
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0144 0.1138 0.4546
Loa Loa (eye worm) inositol-1 0.0039 0.0261 0.054
Loa Loa (eye worm) nuclear factor I 0.0021 0.011 0.0218
Echinococcus multilocularis hemicentin 1 0.001 0.0015 0.0015
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.005 0.0353 0.0726
Plasmodium falciparum ataxin-2 like protein, putative 0.0039 0.0261 0.0861
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0241 0.0793
Echinococcus granulosus tyrosine protein kinase otk 0.001 0.0015 0.0026
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0261 0.0862
Onchocerca volvulus 0.0256 0.2079 0.9764
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0013 0.0038 0.0771
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0188 0.1509 0.2619
Schistosoma mansoni carbonic anhydrase-related 0.005 0.0353 0.0613
Trypanosoma cruzi PAB1-binding protein , putative 0.0039 0.0261 0.1044
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.005 0.0353 0.0726
Brugia malayi Cytochrome P450 family protein 0.0028 0.0164 0.0322
Brugia malayi MH2 domain containing protein 0.0017 0.0076 0.0132
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.001 0.0019 0.0019
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0071 0.0156
Schistosoma mansoni Smad4 0.0039 0.0255 0.0442
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0169 0.1354 0.4754
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0072 0.0285
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Plasmodium falciparum glutathione reductase 0.004 0.0262 0.0868
Brugia malayi MH2 domain containing protein 0.0039 0.0255 0.0516
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0315 0.0547
Schistosoma mansoni hypothetical protein 0.0663 0.5495 0.9538
Schistosoma mansoni hypothetical protein 0.001 0.0019 0.0033
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0129 0.0246
Brugia malayi beta-lactamase 0.0038 0.0252 0.0511
Loa Loa (eye worm) hypothetical protein 0.0015 0.0057 0.0105
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0109 0.0845 0.1788
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0345 0.2827 0.2827
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0262 0.1052
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0107 0.0186
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0252 0.0252
Brugia malayi Cytochrome P450 family protein 0.0017 0.0072 0.0125
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.001 0.0019 0.0033
Trypanosoma brucei trypanothione reductase 0.0114 0.0888 0.3529
Loa Loa (eye worm) hypothetical protein 0.0052 0.0368 0.077
Schistosoma mansoni hypothetical protein 0.0663 0.5495 0.9538
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0126 0.0984 0.1709
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0046 0.0317 0.055
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0015 0.0015
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.004 0.0262 0.0868
Trypanosoma cruzi DNA polymerase kappa, putative 0.0015 0.0057 0.0225
Echinococcus granulosus mothers against decapentaplegic 2 0.0017 0.0076 0.0131
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0015 0.0026
Plasmodium vivax glutathione reductase, putative 0.0114 0.0888 0.3095
Brugia malayi Pre-SET motif family protein 0.0203 0.1634 0.3467
Brugia malayi Smad1 0.0039 0.0255 0.0516
Schistosoma mansoni carbonic anhydrase-related 0.005 0.0353 0.0613
Leishmania major dihydrolipoamide dehydrogenase, putative 0.004 0.0262 0.1052
Brugia malayi mothers against decapentaplegic homolog 3 0.0017 0.0076 0.0132
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0105 0.0812 0.2825
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0686 0.1191
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.004 0.0262 0.0868
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0105 0.0812 0.3222
Brugia malayi Peroxidasin 0.001 0.0016 0.0005
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0052 0.0368 0.0759
Loa Loa (eye worm) MH2 domain-containing protein 0.0567 0.4687 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0129 0.033
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0252 0.0701
Schistosoma mansoni nephrin 0.001 0.0015 0.0026
Echinococcus granulosus dna polymerase eta 0.0015 0.0057 0.01
Schistosoma mansoni cell adhesion molecule 0.001 0.0015 0.0026
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0018 0.0079 0.0079
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.029 0.1102
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.004 0.0262 0.073
Leishmania major cytochrome p450-like protein 0.0017 0.0072 0.0285
Trypanosoma brucei hypothetical protein, conserved 0.0105 0.0812 0.3222
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0129 0.033
Loa Loa (eye worm) TAR-binding protein 0.0109 0.0845 0.1788
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.018 0.018
Echinococcus granulosus carbonic anhydrase II 0.0136 0.1069 0.1855
Schistosoma mansoni tyrosine kinase 0.0012 0.0028 0.0049
Plasmodium vivax SET domain protein, putative 0.003 0.018 0.0573
Leishmania major protein kinase, putative 0.0013 0.0038 0.0145
Echinococcus granulosus carbonic anhydrase 0.005 0.0353 0.0613
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0046 0.0317 0.1061
Schistosoma mansoni carbonic anhydrase 0.005 0.0353 0.0613
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0262 0.1052
Schistosoma mansoni hypothetical protein 0.0021 0.0107 0.0186
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.001 0.0019 0.007
Schistosoma mansoni cpg binding protein 0.0031 0.0187 0.0325
Echinococcus multilocularis basement membrane specific heparan sulfate 0.001 0.0018 0.0018
Mycobacterium tuberculosis Probable oxidoreductase 0.0289 0.2357 0.7013
Schistosoma mansoni titin 0.001 0.0015 0.0026
Onchocerca volvulus 0.0046 0.0315 0.1448
Loa Loa (eye worm) hypothetical protein 0.0024 0.0129 0.0258
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0105 0.0812 0.2825
Schistosoma mansoni ap endonuclease 0.0037 0.0241 0.0419
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0046 0.0317 0.055
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0128 0.0569
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0345 0.2827 0.6019
Schistosoma mansoni single-minded 0.0049 0.0342 0.0593
Toxoplasma gondii hypothetical protein 0.0105 0.0812 0.4118
Schistosoma mansoni septate junction protein 0.001 0.0015 0.0026
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0046 0.0317 0.0648
Trypanosoma brucei carbonic anhydrase-like protein 0.0136 0.1069 0.4264
Loa Loa (eye worm) hypothetical protein 0.0038 0.0252 0.0522
Brugia malayi Latrophilin receptor protein 2 0.0075 0.0557 0.1163
Brugia malayi hypothetical protein 0.0025 0.0144 0.0278
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0315 0.0547
Loa Loa (eye worm) MH1 domain-containing protein 0.0039 0.0255 0.0527
Trypanosoma cruzi hypothetical protein, conserved 0.0105 0.0812 0.3267
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0136 0.1069 0.4302
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0261 0.0862
Schistosoma mansoni myelin transcription factor 1 myt1 0.0052 0.0368 0.064
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0107 0.0186
Loa Loa (eye worm) glutathione reductase 0.0114 0.0888 0.188
Brugia malayi ImpB/MucB/SamB family protein 0.0015 0.0057 0.0093
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0038 0.0145
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0345 0.2827 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0038 0.0067
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.001 0.0015 0.0015
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0017 0.0072 0.016
Brugia malayi hypothetical protein 0.0117 0.091 0.1918
Plasmodium falciparum flap endonuclease 1 0.0026 0.0148 0.0461
Trypanosoma cruzi DNA polymerase kappa, putative 0.0015 0.0057 0.0225
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0345 0.2827 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.004 0.0262 0.1052
Onchocerca volvulus 0.003 0.018 0.0809
Echinococcus multilocularis contactin neuroglian septate junction protein 0.001 0.0015 0.0015
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.001 0.0019 0.0033
Schistosoma mansoni hypothetical protein 0.0075 0.0557 0.0967
Schistosoma mansoni microtubule-associated protein tau 0.0694 0.5761 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0071 0.0156
Mycobacterium ulcerans hypothetical protein 0.0075 0.0558 0.1618
Echinococcus granulosus microtubule associated protein 2 0.0694 0.5761 1
Toxoplasma gondii NADPH-glutathione reductase 0.004 0.0262 0.1265
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0046 0.0317 0.1061
Loa Loa (eye worm) hypothetical protein 0.0018 0.0079 0.0151
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0148 0.0461
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0015 0.0057 0.0116
Echinococcus granulosus carbonic anhydrase 0.005 0.0353 0.0613
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0129 0.0513
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0038 0.0067
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0105 0.0812 0.3222
Trypanosoma brucei DNA polymerase IV, putative 0.0015 0.0057 0.0159
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0252 0.0701
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.018 0.0835
Loa Loa (eye worm) hypothetical protein 0.0038 0.0252 0.0522
Trypanosoma brucei DNA polymerase eta, putative 0.0015 0.0057 0.0159
Loa Loa (eye worm) RNA binding protein 0.0109 0.0845 0.1788
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.005 0.0353 0.0726
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.004 0.0262 0.0992
Brugia malayi PAS domain containing protein 0.0049 0.0342 0.0702
Echinococcus granulosus thioredoxin glutathione reductase 0.0114 0.0888 0.1541
Echinococcus multilocularis lachesin 0.001 0.0015 0.0015
Giardia lamblia Rab geranylgeranyltransferase 0.0105 0.0812 0.2825
Mycobacterium ulcerans hypothetical protein 0.016 0.1275 0.3766
Treponema pallidum licC protein (licC) 0.0075 0.0558 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0454 0.0789
Trypanosoma cruzi DNA polymerase kappa, putative 0.0015 0.0057 0.0225
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0315 0.0547
Schistosoma mansoni polycystin 1-related 0.0021 0.0107 0.0186
Trypanosoma cruzi PAB1-binding protein , putative 0.0039 0.0261 0.1044
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0038 0.0067
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0046 0.0317 0.066
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0038 0.0067
Brugia malayi glutathione reductase 0.0114 0.0888 0.187
Entamoeba histolytica hypothetical protein 0.0117 0.091 0.3175
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0252 0.0701
Echinococcus granulosus GPCR family 2 0.0075 0.0557 0.0967
Trypanosoma cruzi DNA polymerase eta, putative 0.0015 0.0057 0.0225
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0408 0.3354 1
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0304 0.2482 1
Echinococcus multilocularis cpg binding protein 0.0031 0.0187 0.0187
Echinococcus multilocularis mothers against decapentaplegic 2 0.0017 0.0076 0.0076
Echinococcus multilocularis carbonic anhydrase II 0.0136 0.1069 0.1069
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0252 0.0701
Brugia malayi Flap endonuclease-1 0.0026 0.0148 0.0288
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0235 0.0648
Loa Loa (eye worm) hypothetical protein 0.0021 0.0107 0.0211
Entamoeba histolytica hypothetical protein 0.0117 0.091 0.3175
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0261 0.1256
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.001 0.0019 0.0019
Leishmania major hypothetical protein, conserved 0.001 0.0019 0.007
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0315 0.0315
Loa Loa (eye worm) programmed cell death 8 0.001 0.0019 0.0023
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0129 0.033
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0075 0.0558 0.2801
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0046 0.0317 0.1547
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0129 0.0392
Brugia malayi MH1 domain containing protein 0.0039 0.0255 0.0516
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0046 0.0317 0.0648
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0148 0.0529
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0169 0.1354 0.235
Brugia malayi MH2 domain containing protein 0.0039 0.0255 0.0516
Schistosoma mansoni hypothetical protein 0.0286 0.2331 0.4046
Leishmania major lanosterol synthase, putative 0.0047 0.0322 0.1294
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0686 0.1191
Echinococcus granulosus sulfide:quinone oxidoreductase 0.001 0.0019 0.0033
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Echinococcus multilocularis muscleblind protein 1 0.0143 0.1135 0.1135
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.1634 0.3475
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.026 0.2114 0.6282
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.1138 0.4582
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0169 0.1354 0.2876
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0038 0.0065
Schistosoma mansoni Smad4 0.0017 0.0076 0.0131
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0046 0.0317 0.066
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0129 0.033
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0084 0.0633 0.1099
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0046 0.0317 0.1212
Echinococcus granulosus single minded 2 0.0036 0.0235 0.0408
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0046 0.0317 0.1547
Brugia malayi hypothetical protein 0.0039 0.0261 0.0528
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.001 0.0019 0.007
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0136 0.1069 0.1855
Mycobacterium ulcerans hypothetical protein 0.0038 0.0252 0.0701
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0169 0.1354 0.4754
Toxoplasma gondii ABC1 family protein 0.0038 0.0252 0.1213
Trypanosoma cruzi DNA polymerase kappa, putative 0.0015 0.0057 0.0225
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0084 0.0633 0.1325
Brugia malayi ImpB/MucB/SamB family protein 0.0015 0.0057 0.0093
Plasmodium falciparum thioredoxin reductase 0.0114 0.0888 0.3095
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.026 0.2114 0.6282
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.004 0.0262 0.1052
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0164 0.0334
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0002
Schistosoma mansoni lipoxygenase 0.0088 0.0667 0.1158
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0128 0.0328
Schistosoma mansoni smad 0.0017 0.0076 0.0131
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0261 0.1045
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.004 0.0262 0.0455
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0128 0.0328
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0129 0.033
Schistosoma mansoni disulfide oxidoreductase 0.001 0.0019 0.0033
Loa Loa (eye worm) hypothetical protein 0.005 0.0353 0.0738
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0252 0.0832
Echinococcus granulosus muscleblind protein 0.0143 0.1135 0.197
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.001 0.0018 0.0032
Echinococcus granulosus Smad4 0.0039 0.0255 0.0442
Echinococcus granulosus dna polymerase kappa 0.0015 0.0057 0.01
Echinococcus multilocularis geminin 0.0663 0.5495 0.5495
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.004 0.0262 0.0992
Mycobacterium ulcerans DNA polymerase IV 0.0015 0.0057 0.0116
Schistosoma mansoni septate junction protein 0.001 0.0015 0.0026
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0129 0.033
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0252 0.1011
Schistosoma mansoni inositol monophosphatase 0.0039 0.0261 0.0453
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0046 0.0317 0.0317
Echinococcus multilocularis Smad4 0.0039 0.0255 0.0255
Loa Loa (eye worm) beta-lactamase 0.0038 0.0252 0.0522
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0038 0.0067
Schistosoma mansoni tar DNA-binding protein 0.0109 0.0845 0.1466
Toxoplasma gondii hypothetical protein 0.0049 0.0342 0.1679
Brugia malayi Inositol-1 0.0039 0.0261 0.0528
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0345 0.2827 0.6024
Echinococcus multilocularis hemicentin 1 0.001 0.0015 0.0015
Mycobacterium tuberculosis Conserved protein 0.0038 0.0252 0.0701
Leishmania major hypothetical protein, conserved 0.0039 0.0261 0.1044
Loa Loa (eye worm) hypothetical protein 0.0247 0.2003 0.4263
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0107 0.0107
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0169 0.1354 0.4754
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0252 0.0832
Loa Loa (eye worm) latrophilin receptor protein 2 0.0075 0.0557 0.1174
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.001 0.0018 0.0032
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0129 0.033
Loa Loa (eye worm) hypothetical protein 0.001 0.0019 0.0023
Brugia malayi RNA binding protein 0.0109 0.0845 0.1778
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0261 0.0862
Loa Loa (eye worm) hypothetical protein 0.0018 0.0079 0.0151
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Leishmania major DNA polymerase kappa, putative 0.0015 0.0057 0.0225
Schistosoma mansoni terminal deoxycytidyl transferase 0.0015 0.0057 0.01
Brugia malayi basement membrane proteoglycan precursor 0.001 0.0018 0.0009
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0686 0.0686
Loa Loa (eye worm) hypothetical protein 0.003 0.018 0.0367
Schistosoma mansoni roundabout 0.001 0.0015 0.0026
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0317 0.1271
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.001 0.0019 0.007
Schistosoma mansoni lipoxygenase 0.0126 0.0984 0.1709
Echinococcus multilocularis smad 0.0039 0.0255 0.0255
Schistosoma mansoni hypothetical protein 0.0412 0.3386 0.5878
Leishmania major hypothetical protein, conserved 0.001 0.0019 0.007
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.001 0.0015 0.0015
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0169 0.1354 0.4754
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0136 0.1069 0.2267
Plasmodium falciparum ataxin-2 like protein, putative 0.0039 0.0261 0.0861
Schistosoma mansoni flap endonuclease-1 0.0023 0.0127 0.0221
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0252 0.0951
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.018 0.0312
Loa Loa (eye worm) hypothetical protein 0.0038 0.0252 0.0522
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0105 0.0812 0.3267
Schistosoma mansoni sulfide quinone reductase 0.001 0.0019 0.0033
Brugia malayi hypothetical protein 0.0164 0.131 0.2773
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0038 0.0063
Brugia malayi CXXC zinc finger family protein 0.0029 0.0173 0.0341
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0015 0.0055 0.0223
Plasmodium falciparum thioredoxin reductase 0.004 0.0262 0.0868
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.004 0.0262 0.0262
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0093 0.0708 0.2068
Trichomonas vaginalis set domain proteins, putative 0.0231 0.1868 0.6588
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0241 0.0793
Loa Loa (eye worm) hypothetical protein 0.0024 0.0129 0.0258
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0105 0.0812 0.1708
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0252 0.0701
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0109 0.0845 0.1466
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.004 0.0262 0.0868
Leishmania major hypothetical protein, conserved 0.001 0.0019 0.007
Onchocerca volvulus 0.0036 0.0235 0.107
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0046 0.0317 0.055
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0289 0.2357 0.7013
Brugia malayi hypothetical protein 0.0021 0.0107 0.0199
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0169 0.1354 0.6929
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.001 0.0019 0.007
Echinococcus granulosus carbonic anhydrase 0.005 0.0353 0.0613
Trypanosoma cruzi NADH dehydrogenase, putative 0.001 0.0019 0.007
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0252 0.0701
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0075 0.0557 0.0967
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0038 0.0145
Loa Loa (eye worm) hypothetical protein 0.0038 0.0252 0.0522
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0345 0.2827 0.4906
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.0408 0.3354 1
Trypanosoma brucei NADH dehydrogenase 0.001 0.0019 0.0003
Echinococcus multilocularis GPCR, family 2 0.0075 0.0557 0.0557
Entamoeba histolytica hypothetical protein 0.0117 0.091 0.3175
Trypanosoma cruzi lanosterol synthase, putative 0.0093 0.0708 0.2849
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0136 0.1069 0.2258
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0015 0.0057 0.01
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0289 0.2357 0.7013
Plasmodium falciparum geranylgeranyltransferase, putative 0.0046 0.0317 0.1061
Toxoplasma gondii exonuclease III APE 0.0037 0.0241 0.1155
Mycobacterium ulcerans flavoprotein disulfide reductase 0.004 0.0262 0.073
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0345 0.2827 0.4906
Mycobacterium ulcerans lipase LipD 0.0038 0.0252 0.0701
Echinococcus multilocularis carbonic anhydrase 0.005 0.0353 0.0353
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0114 0.0888 0.2606
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0107 0.0314
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0129 0.0392
Echinococcus granulosus geminin 0.0663 0.5495 0.9538
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.001 0.0019 0.0011
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.004 0.0262 0.073
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0038 0.0145
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0165 0.0287
Loa Loa (eye worm) hypothetical protein 0.005 0.0353 0.0738
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0262 0.1052
Brugia malayi MH1 domain containing protein 0.0039 0.0255 0.0516
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0072 0.0137
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.018 0.0312
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0241 0.0667
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0261 0.0862
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0038 0.0145
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0071 0.0156
Schistosoma mansoni sulfide quinone reductase 0.001 0.0019 0.0033
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0686 0.1191
Onchocerca volvulus 0.0247 0.2003 0.9406
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0009 0.0007 0.0013
Mycobacterium ulcerans DNA polymerase IV 0.0015 0.0057 0.0116
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0126 0.0984 0.0984
Schistosoma mansoni hypothetical protein 0.0075 0.0557 0.0967
Loa Loa (eye worm) hypothetical protein 0.0236 0.1911 0.4067
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.001 0.0019 0.007
Giardia lamblia Rab geranylgeranyltransferase 0.0046 0.0317 0.1061
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0241 0.0499
Mycobacterium leprae Probable lipase LipE 0.0038 0.0252 0.0701
Trichomonas vaginalis DNA polymerase eta, putative 0.0015 0.0057 0.0137
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0161 0.1284 0.2728
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0252 0.0511
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.001 0.0019 0.0033
Trypanosoma cruzi protein farnesyltransferase, putative 0.0169 0.1354 0.545
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0038 0.0067
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0304 0.2482 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Schistosoma mansoni smad1 5 8 and 0.0039 0.0255 0.0442
Leishmania major mitochondrial DNA polymerase beta 0.0304 0.2482 1
Toxoplasma gondii hypothetical protein 0.005 0.0353 0.1737
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0252 0.0701
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0241 0.0906
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0075 0.0557 0.0557
Loa Loa (eye worm) hypothetical protein 0.0345 0.2827 0.6024
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0117 0.091 0.158
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.001 0.0015 0.0015
Onchocerca volvulus 0.0013 0.0038 0.0139
Schistosoma mansoni smad1 5 8 and 0.0039 0.0255 0.0442
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0117 0.091 0.091
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.001 0.0019 0.007
Schistosoma mansoni hypothetical protein 0.0075 0.0557 0.0967
Schistosoma mansoni tar DNA-binding protein 0.0109 0.0845 0.1466
Echinococcus granulosus glutamate synthase 0.001 0.0019 0.0033
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.001 0.0019 0.0019
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0169 0.1354 0.2867
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0169 0.1354 0.4754
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0105 0.0812 0.141
Echinococcus multilocularis dna polymerase kappa 0.0015 0.0057 0.0057
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0129 0.0246
Schistosoma mansoni rab6-interacting 0.0021 0.0107 0.0186
Echinococcus multilocularis roundabout 2 0.001 0.0015 0.0015
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.029 0.1161
Trypanosoma brucei DNA polymerase IV, putative 0.0015 0.0057 0.0159
Schistosoma mansoni cell adhesion molecule 0.001 0.0015 0.0026
Leishmania major trypanothione reductase 0.0114 0.0888 0.3572
Echinococcus multilocularis histone acetyltransferase MYST2 0.0052 0.0368 0.0368
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0686 0.1191
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0252 0.0832
Echinococcus granulosus low density lipoprotein receptor ldl 0.001 0.0018 0.0032
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0408 0.3354 1
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0075 0.0558 0.1618
Trypanosoma cruzi trypanothione reductase, putative 0.004 0.0262 0.1052
Echinococcus multilocularis RUN 0.0021 0.0107 0.0107
Toxoplasma gondii hypothetical protein 0.024 0.1945 1
Brugia malayi Muscleblind-like protein 0.0143 0.1135 0.2399
Schistosoma mansoni ap endonuclease 0.0037 0.0241 0.0419
Onchocerca volvulus 0.0038 0.0252 0.1152
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0241 0.0793
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.1138 0.4582
Leishmania major dihydrolipoamide dehydrogenase, putative 0.004 0.0262 0.1052
Schistosoma mansoni loxhd1 0.0021 0.0107 0.0186
Loa Loa (eye worm) hypothetical protein 0.0021 0.0107 0.0211
Mycobacterium ulcerans hypothetical protein 0.0075 0.0558 0.1618
Echinococcus multilocularis tar DNA binding protein 0.0109 0.0845 0.0845
Brugia malayi Calcitonin receptor-like protein seb-1 0.0236 0.1911 0.406
Echinococcus granulosus peroxidasin 0.001 0.0016 0.0028
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0076 0.0144
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.001 0.0015 0.0026
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0129 0.033
Trypanosoma brucei DNA polymerase IV, putative 0.0015 0.0057 0.0159
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0128 0.0328
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0105 0.0812 0.3222
Loa Loa (eye worm) histone methyltransferase 0.001 0.0015 0.0014
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0368 0.1477
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0128 0.4496
Giardia lamblia Rab geranylgeranyltransferase 0.0345 0.2827 1
Echinococcus multilocularis mothers against decapentaplegic 6 0.0017 0.0076 0.0076
Schistosoma mansoni hypothetical protein 0.005 0.0353 0.0613
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0236 0.1911 0.4067
Brugia malayi hypothetical protein 0.0021 0.0107 0.0199
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0128 0.203
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0261 0.1045
Echinococcus multilocularis carbonic anhydrase 0.005 0.0353 0.0353
Loa Loa (eye worm) transcription factor SMAD2 0.0567 0.4687 1
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0128 0.0328
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0029 0.0174 0.0344
Brugia malayi Thioredoxin reductase 0.0114 0.0888 0.187
Loa Loa (eye worm) hypothetical protein 0.0143 0.1135 0.2408
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.004 0.0262 1
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0315 0.0657
Trypanosoma brucei PAB1-binding protein , putative 0.0039 0.0261 0.0984
Onchocerca volvulus 0.0231 0.1868 0.8772
Schistosoma mansoni transcription factor LCR-F1 0.0117 0.091 0.158
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0408 0.3354 1
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0148 0.0592
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.001 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0075 0.0557 0.0967
Echinococcus granulosus tar DNA binding protein 0.0109 0.0845 0.1466
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.001 0.0015 0.0015
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0148 0.0461
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0046 0.0317 0.1271
Brugia malayi hypoxia-induced factor 1 0.0152 0.1203 0.2544
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0236 0.1911 0.406
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0105 0.0812 0.0812
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0252 0.0701
Mycobacterium tuberculosis Probable reductase 0.026 0.2114 0.6282
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0169 0.1354 0.1354
Echinococcus multilocularis muscleblind protein 0.0143 0.1135 0.1135
Onchocerca volvulus 0.0029 0.0173 0.078
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0075 0.0557 0.0967
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0046 0.0317 0.1061
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0289 0.2357 0.7013
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0252 0.0832
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0252 0.0701
Brugia malayi MH2 domain containing protein 0.0567 0.4687 1
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0128 0.0511
Brugia malayi latrophilin 2 splice variant baaae 0.0161 0.1284 0.2719
Mycobacterium tuberculosis Conserved hypothetical protein 0.0015 0.0057 0.0116
Echinococcus granulosus dnaJ subfamily B 0.0412 0.3386 0.5878
Mycobacterium tuberculosis Conserved hypothetical protein 0.0075 0.0558 0.1618
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0169 0.1354 0.4754
Mycobacterium tuberculosis Probable dehydrogenase 0.026 0.2114 0.6282
Schistosoma mansoni neuroglian 0.001 0.0015 0.0026
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0128 0.0569
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.001 0.0019 0.0033
Plasmodium falciparum glutathione reductase 0.0114 0.0888 0.3095
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0148 0.0148
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.001 0.0015 0.0015
Onchocerca volvulus 0.0011 0.002 0.0057
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0241 0.0487
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0038 0.0145
Schistosoma mansoni smad1 5 8 and 0.0039 0.0255 0.0442
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0169 0.1354 0.542
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0017 0.0076 0.0319
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0015 0.0002
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0015 0.0057 0.0225
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.004 0.0262 0.0868
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0169 0.1354 0.235
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0399 0.1976
Schistosoma mansoni carbonic anhydrase-related 0.005 0.0353 0.0613
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0038 0.0067
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.001 0.0019 0.0011
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0046 0.0317 0.1061
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0686 0.1191
Brugia malayi TAR-binding protein 0.0109 0.0845 0.1778
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0072 0.0137
Loa Loa (eye worm) hypothetical protein 0.0038 0.0252 0.0522
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0241 0.0667
Treponema pallidum NADH oxidase 0.004 0.0262 0.4515
Loa Loa (eye worm) hypothetical protein 0.0075 0.0557 0.1174
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0252 0.0701
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.024 0.1945 0.6861
Onchocerca volvulus 0.0024 0.0129 0.057
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0129 0.0513
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0169 0.1354 0.4754
Schistosoma mansoni smad 0.0039 0.0255 0.0442
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0079 0.0214
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0169 0.1354 0.4754
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0169 0.1354 0.4754
Loa Loa (eye worm) hypothetical protein 0.0018 0.0079 0.0151
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.001 0.0019 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0076 0.0144
Toxoplasma gondii LsmAD domain-containing protein 0.0039 0.0261 0.1255
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0015 0.0057 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0057 0.0159
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0105 0.0812 0.3267
Echinococcus granulosus roundabout 2 0.001 0.0015 0.0026
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.001 0.0015 0.0015
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0235 0.0473
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0315 0.1448
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0107 0.0186
Mycobacterium ulcerans beta-lactamase 0.0038 0.0252 0.0701
Entamoeba histolytica hypothetical protein 0.0117 0.091 0.3175
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.001 0.0015 0.0026
Trypanosoma cruzi trypanothione reductase, putative 0.0114 0.0888 0.3572
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0261 0.0726
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.018 0.0312
Trypanosoma cruzi hypothetical protein, conserved 0.0105 0.0812 0.3267
Plasmodium vivax geranylgeranyltransferase, putative 0.0046 0.0317 0.1061
Echinococcus multilocularis neuroglian 0.001 0.0015 0.0015
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0148 0.0592
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.001 0.0019 0.0019
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0241 0.4124
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0261 0.0453
Echinococcus multilocularis glutamate synthase 0.001 0.0019 0.0019
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0105 0.0812 0.3267
Echinococcus multilocularis peroxidasin 0.001 0.0016 0.0016
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.004 0.0262 0.073
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.018 0.0312
Loa Loa (eye worm) hypothetical protein 0.0018 0.0079 0.0151
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0241 0.0667
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0263 0.2139 0.4555
Loa Loa (eye worm) carbonic anhydrase 3 0.0136 0.1069 0.2267
Trypanosoma cruzi NADH dehydrogenase, putative 0.001 0.0019 0.007
Loa Loa (eye worm) hypothetical protein 0.0084 0.0633 0.1336
Schistosoma mansoni inositol monophosphatase 0.0039 0.0261 0.0453
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0128 0.0328
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0046 0.0317 0.1061
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0148 0.0461
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0105 0.0812 0.2825
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.001 0.0019 0.0003
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0148 0.0461
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0107 0.0107
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0245 0.1986 0.5898
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0038 0.0067
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0241 0.0241
Leishmania major farnesyltransferase beta subunit 0.0169 0.1354 0.545
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0052 0.0368 0.0368
Trypanosoma cruzi protein farnesyltransferase, putative 0.0169 0.1354 0.545
Loa Loa (eye worm) hypothetical protein 0.0143 0.1135 0.2408
Echinococcus multilocularis mothers against decapentaplegic 5 0.0039 0.0255 0.0255
Plasmodium falciparum carbonic anhydrase 0.005 0.0353 0.1192
Mycobacterium tuberculosis Conserved hypothetical protein 0.0075 0.0558 0.1618
Echinococcus granulosus TGF beta signal transducer SmadC 0.0039 0.0255 0.0442
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0015
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0252 0.0832
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0315 0.0547
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.001 0.0019 0.007
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0124 0.0968 0.3379
Loa Loa (eye worm) hypothetical protein 0.0021 0.011 0.0218
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0105 0.0812 0.2825
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0345 0.2827 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.029 0.1161
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0241 0.0966
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.005 0.0353 0.0738
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0129 0.0246
Leishmania major DNA polymerase eta, putative 0.0015 0.0057 0.0225
Loa Loa (eye worm) CYP4Cod1 0.0017 0.0072 0.0137
Brugia malayi hypothetical protein 0.0247 0.2003 0.4256
Entamoeba histolytica hypothetical protein 0.0024 0.0128 0.039
Brugia malayi Immunoglobulin I-set domain containing protein 0.0263 0.2139 0.4548
Echinococcus multilocularis L aminoadipate semialdehyde 0.0084 0.0633 0.0633
Schistosoma mansoni hypothetical protein 0.0161 0.1284 0.223
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.001 0.0018 0.0032
Giardia lamblia Prenyltransferase 0.0169 0.1354 0.4754
Loa Loa (eye worm) hypothetical protein 0.0013 0.0038 0.0063
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0075 0.0557 0.1163
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0315 0.0315
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.001 0.0019 0.0019
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0038 0.0145

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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