Detailed information for compound 787346

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 489.998 | Formula: C21H20ClN5O3S2
  • H donors: 0 H acceptors: 3 LogP: 4.48 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCS(=O)(=O)c1nn2c(=NC(=O)/C(=C/c3cc(n(c3C)c3cc(Cl)ccc3C)C)/C2=N)s1
  • InChi: 1S/C21H20ClN5O3S2/c1-5-32(29,30)21-25-27-18(23)16(19(28)24-20(27)31-21)9-14-8-12(3)26(13(14)4)17-10-15(22)7-6-11(17)2/h6-10,23H,5H2,1-4H3/b16-9+,23-18?
  • InChiKey: PWQPFELJVCHGQD-NWECJKKASA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0639 0.3009 0.2999
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0121 0.036
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0022 0.0046 0.0032
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0195 0.0873 0.1345
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0245 0.023
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0115 0.0231
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0121 0.0178
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0031 0.009 0.0101
Entamoeba histolytica Ran family GTPase 0.0044 0.015 0.0451
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0025 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0282 0.1292 0.3048
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0195 0.0873 0.086
Trypanosoma brucei phosphoglycerate kinase 0.0249 0.1133 0.2672
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0411 0.1915 0.2961
Plasmodium falciparum phosphoglycerate kinase 0.0677 0.3192 1
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0199 0.0298
Trypanosoma cruzi polo-like protein kinase, putative 0.0466 0.2179 0.5133
Loa Loa (eye worm) RecQ helicase 0.0024 0.0053 0.0072
Echinococcus multilocularis dnaJ subfamily B 0.0829 0.392 0.3912
Toxoplasma gondii histone lysine methyltransferase SET1 0.0334 0.1545 0.4816
Loa Loa (eye worm) glutaminase 0.1355 0.6453 1
Giardia lamblia PHD finger protein 15 0.0028 0.0074 0.0057
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0055 0.0204 0.019
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0044 0.015 0.0136
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0055 0.0204 0.037
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0029
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0237 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0046 0.0061
Plasmodium vivax glutathione reductase, putative 0.0342 0.1583 0.4958
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0121 0.0178
Loa Loa (eye worm) hypothetical protein 0.0028 0.0074 0.0106
Onchocerca volvulus 0.0024 0.0054 0.022
Loa Loa (eye worm) hypothetical protein 0.0025 0.0057 0.0078
Mycobacterium ulcerans lipase LipD 0.0037 0.0115 0.014
Brugia malayi hypothetical protein 0.0147 0.0644 0.099
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0074 0.0231
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0153 0.0138
Brugia malayi exodeoxyribonuclease III family protein 0.0055 0.0204 0.0307
Onchocerca volvulus 0.0238 0.108 0.4927
Trichomonas vaginalis helicase, putative 0.0039 0.0125 0.0184
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0017 0.002 0.0005
Schistosoma mansoni terminal deoxycytidyl transferase 0.0394 0.183 0.1819
Plasmodium falciparum glutathione reductase 0.0119 0.0508 0.1526
Echinococcus multilocularis microtubule associated protein 2 0.2094 1 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0119 0.0508 0.1199
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0054 0.0113
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0119 0.0508 0.1553
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0058 0.008
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0895 0.4239 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0049 0.0172 0.039
Toxoplasma gondii exonuclease III APE 0.0055 0.0204 0.0597
Brugia malayi M-phase phosphoprotein, mpp8 0.0022 0.0046 0.0061
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0122 0.0525 0.1607
Plasmodium falciparum thioredoxin reductase 0.0119 0.0508 0.1526
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0126 0.0543 0.1281
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0115 0.0231
Echinococcus multilocularis transcription factor Dp 1 0.0113 0.048 0.0466
Onchocerca volvulus 0.006 0.0226 0.101
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0153 0.0675 0.1581
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0031 0.009 0.0075
Schistosoma mansoni cpg binding protein 0.0247 0.1127 0.1115
Schistosoma mansoni phosphoglycerate kinase 0.0677 0.3192 0.3183
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0039 0.0125 0.0112
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0115 0.0231
Plasmodium vivax ferrodoxin reductase, putative 0.0031 0.009 0.0278
Brugia malayi Pre-SET motif family protein 0.0062 0.0237 0.0358
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.022 0.0331
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0051 0.0183 0.0433
Mycobacterium ulcerans hypothetical protein 0.0037 0.0115 0.014
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0424 0.1974 0.4648
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0025 0.0057 0.0078
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0031 0.009 0.0129
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0054 0.0046
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.0039 0.0125 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0125 0.0184
Echinococcus multilocularis disco interacting protein 2 0.0077 0.0308 0.0294
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0031 0.009 0.0129
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0054 0.0074
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0091 0.0265
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0074 0.0188
Brugia malayi beta-lactamase family protein 0.0037 0.0115 0.0168
Trypanosoma brucei NADH dehydrogenase 0.0031 0.009 0.0211
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0031 0.009 0.0197
Brugia malayi SET domain containing protein 0.0028 0.0074 0.0105
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0058 0.0121
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0119 0.0508 0.1186
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0031 0.009 0.0101
Plasmodium vivax JmjC domain containing protein 0.0025 0.0058 0.0178
Echinococcus multilocularis phd:f box containing protein 0.0025 0.0058 0.0043
Trypanosoma brucei chrX additional, unordered contigs 0.0122 0.0525 0.1239
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0025 0.0057 0.0043
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0128 0.0113
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0115 0.0271
Schistosoma mansoni phd/f-box containing protein 0.0025 0.0058 0.0044
Loa Loa (eye worm) hypothetical protein 0.0022 0.0046 0.0061
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0153 0.0139
Schistosoma mansoni glutamate synthase 0.0031 0.009 0.0076
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0171 0.0761 0.117
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0022 0.0046 0.0061
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.0039 0.0125 0.039
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0119 0.0508 0.1199
Plasmodium vivax SET domain protein, putative 0.0062 0.0237 0.0741
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0046 0.0061
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0119 0.0508 0.0495
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0128 0.0265
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0022 0.0046 0.0097
Echinococcus multilocularis cpg binding protein 0.0247 0.1127 0.1114
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.0039 0.0125 0.0296
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0107 0.0453 0.0693
Plasmodium vivax flap endonuclease 1, putative 0.0051 0.0183 0.0572
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0677 0.3192 0.7526
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0031 0.009 0.0075
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0115 0.0168
Onchocerca volvulus Alhambra homolog 0.0028 0.0074 0.0313
Loa Loa (eye worm) hypothetical protein 0.006 0.0226 0.0341
Mycobacterium tuberculosis Probable oxidoreductase 0.0868 0.4108 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0045 0.0153 0.0139
Echinococcus granulosus bloom syndrome protein 0.0024 0.0053 0.0038
Mycobacterium tuberculosis Conserved protein 0.0037 0.0115 0.0231
Trypanosoma brucei hypothetical protein, conserved 0.0031 0.009 0.0211
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.015 0.034
Brugia malayi beta-lactamase 0.0037 0.0115 0.0168
Entamoeba histolytica hypothetical protein 0.0022 0.0046 0.0124
Plasmodium vivax thioredoxin reductase, putative 0.0342 0.1583 0.4958
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0086 0.035 0.1054
Loa Loa (eye worm) hypothetical protein 0.0062 0.0237 0.0358
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0046 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0046 0.0061
Schistosoma mansoni sulfide quinone reductase 0.0031 0.009 0.0076
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0044 0.015 0.0354
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0076 0.0306 0.1375
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0054 0.0046
Toxoplasma gondii thioredoxin reductase 0.0342 0.1583 0.4936
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0053 0.0072
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0029
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0074 0.006
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0115 0.0256
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0031 0.009 0.0261
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0032 0.0093 0.0079
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0781 0.369 0.8976
Entamoeba histolytica disulphide oxidoreductase, putative 0.0031 0.009 0.0261
Schistosoma mansoni sex comb on midleg homolog 0.0094 0.039 0.0377
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0245 0.0342
Echinococcus granulosus CTD small phosphatase protein like 0.0025 0.0057 0.0042
Loa Loa (eye worm) hypothetical protein 0.0024 0.0055 0.0076
Schistosoma mansoni ap endonuclease 0.0055 0.0204 0.0191
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0031 0.009 0.0129
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0121 0.0178
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0677 0.3192 0.7739
Trichomonas vaginalis chromobox protein, putative 0.0082 0.0334 0.0508
Mycobacterium tuberculosis Conserved protein 0.0037 0.0115 0.0231
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0035 0.0105 0.009
Schistosoma mansoni alpha glucosidase 0.0038 0.0121 0.0107
Loa Loa (eye worm) hypothetical protein 0.0022 0.0046 0.0061
Trypanosoma cruzi DNA polymerase kappa, putative 0.0553 0.2596 0.6119
Loa Loa (eye worm) hypothetical protein 0.0022 0.0046 0.0061
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0245 0.0564
Loa Loa (eye worm) hypothetical protein 0.0076 0.0306 0.0465
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.0039 0.0125 0.0349
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0074 0.0106
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0115 0.01
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.009 0.0197
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0245 0.0724
Loa Loa (eye worm) hypothetical protein 0.0017 0.002 0.0021
Plasmodium falciparum ferrodoxin reductase-like protein 0.0031 0.009 0.0204
Leishmania major DNA polymerase kappa, putative 0.0122 0.0525 0.1226
Brugia malayi mbt repeat family protein 0.0094 0.039 0.0596
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0115 0.0168
Echinococcus multilocularis peregrin 0.0035 0.0109 0.0094
Loa Loa (eye worm) hypothetical protein 0.0282 0.1292 0.1994
Brugia malayi jmjC domain containing protein 0.0025 0.0058 0.008
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0022 0.0046 0.0031
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0054 0.0046
Leishmania major phosphoglycerate kinase B, cytosolic 0.0677 0.3192 0.7526
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0055 0.0204 0.0468
Onchocerca volvulus 0.0031 0.009 0.0382
Trypanosoma brucei unspecified product 0.0514 0.2406 0.5676
Trypanosoma brucei DNA polymerase kappa, putative 0.0553 0.2596 0.6125
Brugia malayi CXXC zinc finger family protein 0.0238 0.108 0.1666
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0107 0.0453 0.0439
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0058 0.0121
Loa Loa (eye worm) CXXC zinc finger family protein 0.0238 0.108 0.1666
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0074 0.0188
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0121 0.0178
Trichomonas vaginalis ap endonuclease, putative 0.0055 0.0204 0.0307
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0119 0.0508 0.159
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0025 0.0057 0.0175
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0153 0.0138
Plasmodium vivax phosphoglycerate kinase, putative 0.0677 0.3192 1
Loa Loa (eye worm) heterochromatin protein 1 0.0136 0.0594 0.0912
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0032 0.0094 0.0137
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0031 0.009 0.0211
Echinococcus multilocularis 0.0025 0.0057 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0125 0.0184
Trichomonas vaginalis CAMK family protein kinase 0.0231 0.1048 0.1615
Schistosoma mansoni zinc finger protein 0.0017 0.002 0.0006
Mycobacterium ulcerans monoxygenase 0.0031 0.009 0.0101
Trichomonas vaginalis chromobox protein, putative 0.0136 0.0594 0.0912
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0054 0.015
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0025 0.0057 0.0132
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0046 0.014
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0382 0.1773 0.1761
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0031 0.009 0.0129
Schistosoma mansoni ran 0.0044 0.015 0.0137
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0074 0.006
Mycobacterium tuberculosis Conserved protein 0.0037 0.0115 0.0231
Trichomonas vaginalis CAMK family protein kinase 0.0466 0.2179 0.3371
Schistosoma mansoni glutaminase 0.1355 0.6453 0.6448
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0677 0.3192 0.7526
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0031 0.009 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0199 0.0298
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0119 0.0508 0.1526
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0031 0.009 0.0278
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0031 0.009 0.0075
Plasmodium falciparum flap endonuclease 1 0.0051 0.0183 0.0501
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0046 0.0061
Brugia malayi Pre-SET motif family protein 0.0411 0.1915 0.2961
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0031 0.009 0.0197
Echinococcus multilocularis lysine specific demethylase 6a 0.0025 0.0058 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0025 0.0029
Echinococcus multilocularis flap endonuclease 1 0.0051 0.0183 0.0169
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0119 0.0508 0.1186
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0091 0.0199
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0119 0.0508 0.1186
Trichomonas vaginalis set domain proteins, putative 0.0468 0.2186 0.3381
Onchocerca volvulus 0.0022 0.0046 0.0181
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.002 0.0033 0.0026
Brugia malayi ImpB/MucB/SamB family protein 0.0394 0.183 0.2829
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0125 0.0184
Schistosoma mansoni chromobox protein 0.0022 0.0046 0.0032
Schistosoma mansoni hypothetical protein 0.0028 0.0074 0.0061
Mycobacterium ulcerans NADH dehydrogenase 0.0031 0.009 0.0101
Echinococcus multilocularis polycomb protein SCMH1 0.0094 0.039 0.0376
Leishmania major NADH dehydrogenase, putative 0.0031 0.009 0.0197
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0466 0.2179 0.2168
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0054 0.015
Trichomonas vaginalis glutaminase, putative 0.1355 0.6453 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0031 0.009 0.0129
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0126 0.0543 0.1268
Schistosoma mansoni cpg binding protein 0.0238 0.108 0.1068
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0119 0.0508 0.1186
Loa Loa (eye worm) flap endonuclease-1 0.0051 0.0183 0.0275
Trypanosoma brucei DNA polymerase IV, putative 0.0553 0.2596 0.6125
Brugia malayi jmjC domain containing protein 0.0103 0.0433 0.0662
Leishmania major hypothetical protein, conserved 0.0031 0.009 0.0197
Echinococcus multilocularis snurportin 1 0.0639 0.3009 0.2999
Trichomonas vaginalis CAMK family protein kinase 0.0466 0.2179 0.3371
Trypanosoma brucei DNA polymerase kappa, putative 0.0311 0.1433 0.338
Brugia malayi chromobox protein homolog 3 0.0076 0.0306 0.0465
Loa Loa (eye worm) hypothetical protein 0.0016 0.0015 0.0013
Entamoeba histolytica hypothetical protein 0.0022 0.0046 0.0124
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0121 0.0178
Trichomonas vaginalis chromobox protein, putative 0.0136 0.0594 0.0912
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0031 0.009 0.0075
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0245 0.023
Echinococcus granulosus dna polymerase kappa 0.0553 0.2596 0.2586
Echinococcus granulosus SAM and MBT domain containing protein 0.0094 0.039 0.0376
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0058 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0125 0.0184
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0121 0.0178
Schistosoma mansoni importin beta-1 0.006 0.0226 0.0213
Echinococcus granulosus dnaJ subfamily B 0.0829 0.392 0.3912
Trypanosoma cruzi NADH dehydrogenase, putative 0.0031 0.009 0.0197
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0107 0.0453 0.0439
Trypanosoma brucei hypothetical protein, conserved 0.0122 0.0525 0.1239
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0055 0.0204 0.0468
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0046 0.0061
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0044 0.015 0.0223
Loa Loa (eye worm) jmjC domain-containing protein 0.0103 0.0433 0.0662
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0781 0.369 0.8976
Trypanosoma brucei DNA damage repair protein, putative 0.0122 0.0525 0.1239
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0086 0.035 0.1093
Echinococcus granulosus histone acetyltransferase MYST2 0.0107 0.0453 0.0439
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0119 0.0508 0.1199
Loa Loa (eye worm) hypothetical protein 0.0621 0.2925 0.4528
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0055 0.0204 0.0307
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0115 0.0231
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0031 0.009 0.017
Trichomonas vaginalis CAMK family protein kinase 0.0231 0.1048 0.1615
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.009 0.0197
Entamoeba histolytica acetyltransferase, GNAT family 0.0078 0.0315 0.097
Brugia malayi Phosphoglycerate kinase 0.0677 0.3192 0.4942
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0466 0.2179 0.5133
Loa Loa (eye worm) acetyltransferase 0.0291 0.1337 0.2064
Loa Loa (eye worm) hypothetical protein 0.0022 0.0046 0.0061
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0054 0.0046
Entamoeba histolytica serine/threonine protein kinase, putative 0.0466 0.2179 0.6821
Echinococcus multilocularis JmjC domain containing protein 4 0.0025 0.0058 0.0043
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0153 0.0227
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0119 0.0508 0.1526
Schistosoma mansoni hypothetical protein 0.0165 0.0732 0.072
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0868 0.4108 1
Mycobacterium ulcerans phosphoglycerate kinase 0.0677 0.3192 0.4927
Echinococcus multilocularis chromobox protein 1 0.0136 0.0594 0.058
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0025 0.0057 0.0042
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0055 0.0204 0.0638
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0031 0.009 0.0197
Mycobacterium tuberculosis Probable dehydrogenase 0.0781 0.369 0.8976
Mycobacterium tuberculosis Conserved hypothetical protein 0.0471 0.2204 0.5341
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0031 0.009 0.0197
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0031 0.009 0.0101
Trypanosoma cruzi hypothetical protein, conserved 0.0122 0.0525 0.1226
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0119 0.0508 0.1186
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0046 0.0061
Brugia malayi F/Y-rich N-terminus family protein 0.0064 0.0245 0.037
Echinococcus granulosus chromobox protein 2 0.0022 0.0046 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.0553 0.2596 0.6125
Schistosoma mansoni alpha-glucosidase 0.0147 0.0646 0.0633
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0119 0.0508 0.1186
Trypanosoma brucei phosphoglycerate kinase, putative 0.0249 0.1133 0.2672
Trypanosoma brucei DNA polymerase kappa, putative 0.0553 0.2596 0.6125
Loa Loa (eye worm) hypothetical protein 0.0024 0.0054 0.0074
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0031 0.009 0.0105
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0031 0.009 0.017
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0167 0.074 0.2259
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0056 0.0209 0.0195
Loa Loa (eye worm) hypothetical protein 0.0037 0.0115 0.0168
Entamoeba histolytica hypothetical protein 0.002 0.0036 0.0092
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0055 0.0204 0.0279
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0025 0.0029
Loa Loa (eye worm) hypothetical protein 0.006 0.0226 0.0342
Echinococcus multilocularis chromobox protein 1 0.0136 0.0594 0.058
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0121 0.0271
Onchocerca volvulus 0.0094 0.039 0.1762
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0051 0.0183 0.0531
Mycobacterium ulcerans hypothetical protein 0.0471 0.2204 0.339
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0119 0.0508 0.1186
Echinococcus multilocularis dna polymerase kappa 0.0553 0.2596 0.2586
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0306 0.0465
Leishmania major hypothetical protein, conserved 0.0025 0.0058 0.0121
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0031 0.009 0.0087
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0119 0.0508 0.1194
Trichomonas vaginalis ran, putative 0.0044 0.015 0.0223
Onchocerca volvulus 0.0037 0.0115 0.0498
Loa Loa (eye worm) hypothetical protein 0.0025 0.0058 0.008
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0249 0.1133 0.2661
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0045 0.0153 0.0139
Schistosoma mansoni hypothetical protein 0.0829 0.392 0.3912
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0025 0.0057 0.0043
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0061 0.0232 0.0351
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0055 0.0204 0.0482
Chlamydia trachomatis thioredoxin reductase 0.0031 0.009 0.0204
Echinococcus granulosus zinc finger protein 0.0017 0.002 0.0005
Leishmania major GTP-binding protein, putative 0.0044 0.015 0.034
Mycobacterium leprae Probable lipase LipE 0.0037 0.0115 0.0149
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0085 0.0345 0.0331
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0394 0.183 0.1818
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0051 0.0183 0.0418
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0868 0.4108 1
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0025 0.0058 0.0135
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0179 0.0798 0.3634
Loa Loa (eye worm) hypothetical protein 0.0147 0.0644 0.099
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0172 0.0256
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0044 0.015 0.0467
Loa Loa (eye worm) hypothetical protein 0.0064 0.0247 0.0374
Brugia malayi Heterochromatin protein 1 0.0136 0.0594 0.0912
Trypanosoma brucei DNA polymerase kappa, putative 0.0553 0.2596 0.6125
Trichomonas vaginalis apoptosis inducing factor, putative 0.0031 0.009 0.0129
Trypanosoma cruzi DNA polymerase kappa, putative 0.0553 0.2596 0.6119
Giardia lamblia DINP protein human, muc B family 0.0433 0.202 0.6263
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0031 0.009 0.0075
Schistosoma mansoni microtubule-associated protein tau 0.2094 1 1
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0091 0.0199
Brugia malayi PHD-finger family protein 0.0017 0.002 0.0021
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0121 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0024 0.0054 0.0074
Plasmodium vivax hypothetical protein, conserved 0.002 0.0033 0.0101
Trypanosoma brucei phosphoglycerate kinase 0.0677 0.3192 0.7529
Echinococcus granulosus chromobox protein 1 0.0136 0.0594 0.058
Echinococcus granulosus glutamate synthase 0.0031 0.009 0.0075
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0031 0.009 0.0101
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0119 0.0508 0.159
Brugia malayi jmjC domain containing protein 0.0025 0.0058 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0046 0.0061
Chlamydia trachomatis phosphoglycerate kinase 0.0677 0.3192 1
Trichomonas vaginalis rotamase, putative 0.0032 0.0094 0.0137
Brugia malayi Phosphoglycerate kinase 0.0249 0.1133 0.1747
Plasmodium falciparum glutathione reductase 0.0342 0.1583 0.492
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0055 0.0204 0.0451
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0153 0.0138
Trichomonas vaginalis rotamase, putative 0.0032 0.0091 0.0131
Schistosoma mansoni protein phosphatase 2C 0.0025 0.0058 0.0044
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0055 0.0204 0.0622
Plasmodium falciparum importin beta, putative 0.006 0.0226 0.0635
Trypanosoma brucei importin beta-1 subunit, putative 0.006 0.0226 0.0533
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0094 0.0137
Toxoplasma gondii selenide, water dikinase 0.0031 0.009 0.0236
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0046 0.0124
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0061 0.0232 0.0351
Loa Loa (eye worm) hypothetical protein 0.0677 0.3192 0.4942
Schistosoma mansoni hypothetical protein 0.0583 0.274 0.273
Leishmania major hypothetical protein, conserved 0.0031 0.009 0.0197
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0046 0.0061
Schistosoma mansoni hypothetical protein 0.0165 0.0732 0.072
Onchocerca volvulus 0.0016 0.0014 0.0034
Giardia lamblia DNA damage repair protein 0.0122 0.0525 0.1495
Trichomonas vaginalis esterase, putative 0.0037 0.0115 0.0168
Trichomonas vaginalis bromodomain-containing protein, putative 0.0086 0.035 0.0533
Trypanosoma brucei DNA polymerase kappa, putative 0.0553 0.2596 0.6125
Schistosoma mansoni jumonji/arid domain-containing protein 0.0103 0.0433 0.042
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0291 0.1337 0.1325
Brugia malayi N-terminal motif family protein 0.0179 0.0798 0.1229
Echinococcus granulosus disco interacting protein 2 0.0077 0.0308 0.0294
Trichomonas vaginalis glutamate synthase, putative 0.0031 0.009 0.0129
Schistosoma mansoni DNA polymerase IV / kappa 0.0122 0.0525 0.0512
Echinococcus granulosus lysosomal alpha glucosidase 0.0171 0.0761 0.0747
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0115 0.0101
Brugia malayi Bromodomain containing protein 0.0035 0.0109 0.0159
Trypanosoma brucei DNA polymerase IV, putative 0.0553 0.2596 0.6125
Loa Loa (eye worm) hypothetical protein 0.012 0.0514 0.0788
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0781 0.369 0.8967
Plasmodium vivax heterochromatin protein 1, putative 0.0022 0.0046 0.014
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0119 0.0508 0.0752
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0054 0.0113
Trypanosoma brucei DNA damage repair protein, putative 0.0122 0.0525 0.1239
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0677 0.3192 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0171 0.0761 0.0747
Trypanosoma brucei unspecified product 0.0271 0.1243 0.2932
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0121 0.0271
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0032 0.0094 0.0137
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0031 0.009 0.0075
Echinococcus multilocularis SAM and MBT domain containing protein 0.0094 0.039 0.0376
Trypanosoma cruzi DNA polymerase eta, putative 0.035 0.1621 0.3814
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0043 0.0146 0.0217
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0044 0.015 0.0395
Echinococcus granulosus phosphoglycerate kinase 1 0.0677 0.3192 0.3182
Entamoeba histolytica phosphoglycerate kinase, putative 0.0677 0.3192 1
Schistosoma mansoni myst-related protein 0.002 0.0036 0.0022
Echinococcus multilocularis expressed protein 0.0032 0.0094 0.008
Leishmania major importin beta-1 subunit, putative 0.0049 0.0172 0.039
Onchocerca volvulus 0.0147 0.0644 0.2927
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0172 0.0256
Trichomonas vaginalis dullard protein, putative 0.0025 0.0057 0.0078
Schistosoma mansoni alpha-glucosidase 0.0147 0.0646 0.0633
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0031 0.009 0.0236
Trypanosoma cruzi NADH dehydrogenase, putative 0.0031 0.009 0.0197
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0046 0.0061
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0126 0.0543 0.1268
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0115 0.0357
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0245 0.0342
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0121 0.0334
Trypanosoma cruzi trypanothione reductase, putative 0.0342 0.1583 0.3725
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0115 0.0168
Echinococcus multilocularis dna polymerase eta 0.0621 0.2925 0.2915
Echinococcus multilocularis jumonji domain containing 1A 0.0025 0.0058 0.0043
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0119 0.0508 0.1349
Plasmodium falciparum phd finger protein, putative 0.0028 0.0074 0.0157
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0153 0.0227
Brugia malayi Associated with TFs and helicases family protein 0.0022 0.0046 0.0061
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0046 0.0124
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0045 0.0153 0.0139
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0031 0.009 0.0204
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0091 0.0214
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0115 0.0168
Echinococcus granulosus snurportin 1 0.0639 0.3009 0.2999
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0033
Echinococcus granulosus thioredoxin glutathione reductase 0.0347 0.1605 0.1593
Trichomonas vaginalis flap endonuclease-1, putative 0.0051 0.0183 0.0275
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0061 0.0232 0.0351
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0153 0.0138
Leishmania major trypanothione reductase 0.0342 0.1583 0.3725
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0017 0.002 0.0005
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0433 0.202 0.4892
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0054 0.015
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0022 0.0046 0.0032
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0025 0.0057 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0125 0.0184
Echinococcus granulosus transcription factor Dp 1 0.0113 0.048 0.0466
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0054 0.0046
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0046 0.014
Echinococcus multilocularis phosphoglycerate kinase 1 0.0677 0.3192 0.3182
Schistosoma mansoni bromodomain containing protein 0.0017 0.002 0.0006
Trichomonas vaginalis Heterochromatin protein, putative 0.0022 0.0046 0.0061
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0046 0.0124
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0077 0.0308 0.0295
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0119 0.0508 0.1186
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0121 0.0178
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0032 0.0093 0.0078
Leishmania major hypothetical protein, conserved 0.0031 0.009 0.0197
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0195 0.0873 0.2048
Trypanosoma brucei importin beta-1 subunit, putative 0.006 0.0226 0.0533
Echinococcus granulosus lysine specific demethylase 6a 0.0025 0.0058 0.0043
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0061 0.0232 0.0351
Brugia malayi acetyltransferase, GNAT family protein 0.0291 0.1337 0.2064
Onchocerca volvulus 0.0037 0.0115 0.0498
Schistosoma mansoni DNA polymerase eta 0.0621 0.2925 0.2915
Onchocerca volvulus 0.0037 0.0115 0.0498
Schistosoma mansoni ran 0.0044 0.015 0.0137
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0382 0.1773 0.1761
Toxoplasma gondii ImpB/MucB/SamB family protein 0.035 0.1621 0.5054
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0291 0.1337 0.1324
Trypanosoma cruzi trypanothione reductase, putative 0.0119 0.0508 0.1186
Echinococcus multilocularis Chromobox protein 3 0.0022 0.0046 0.0031
Giardia lamblia Phosphoglycerate kinase 0.0677 0.3192 1
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0249 0.1133 0.2661
Giardia lamblia Thioredoxin reductase 0.0031 0.009 0.0105
Loa Loa (eye worm) hypothetical protein 0.0037 0.0115 0.0168
Echinococcus granulosus cpg binding protein 0.0247 0.1127 0.1114
Leishmania major mitochondrial DNA polymerase beta 0.0895 0.4239 1
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0031 0.009 0.017
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0031 0.009 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0121 0.0271
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0091 0.0199
Schistosoma mansoni hypothetical protein 0.0022 0.0046 0.0032
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0025 0.0057 0.0078
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0031 0.009 0.0087
Schistosoma mansoni disulfide oxidoreductase 0.0031 0.009 0.0076
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0031 0.009 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0146 0.0217
Loa Loa (eye worm) hypothetical protein 0.0024 0.0054 0.0074
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0025 0.0057 0.0078
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0055 0.0204 0.0468
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0394 0.183 0.2829
Schistosoma mansoni chromobox protein 0.0136 0.0594 0.0581
Loa Loa (eye worm) CHromoDomain protein family member 0.0032 0.0093 0.0134
Entamoeba histolytica hypothetical protein 0.0049 0.0172 0.0519
Loa Loa (eye worm) helicase 0.0022 0.0046 0.0061
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0119 0.0508 0.1526
Trichomonas vaginalis chromobox protein, putative 0.0082 0.0334 0.0508
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0249 0.1133 0.2661
Schistosoma mansoni jumonji domain containing protein 0.0133 0.0575 0.0562
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0119 0.0508 0.1186
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0031 0.009 0.0075
Echinococcus granulosus GTP binding nuclear protein Ran 0.0044 0.015 0.0136
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0025 0.0057 0.0134
Schistosoma mansoni hypothetical protein 0.0031 0.009 0.0076
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0053 0.0072
Loa Loa (eye worm) hypothetical protein 0.0037 0.0115 0.0168
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0031 0.009 0.0129
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0121 0.0178
Leishmania major hypothetical protein, conserved 0.0025 0.0057 0.0119
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0237 0.0223
Trichomonas vaginalis glutamate synthase, putative 0.0031 0.009 0.0129
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0025 0.0058 0.0136
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0128 0.0113
Trichomonas vaginalis glutathione reductase, putative 0.0119 0.0508 0.0779
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0781 0.369 0.8976
Schistosoma mansoni jumonji/arid domain-containing protein 0.0103 0.0433 0.042
Giardia lamblia NADH oxidase lateral transfer candidate 0.0119 0.0508 0.144
Mycobacterium ulcerans dehydrogenase 0.0031 0.009 0.0101
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0044 0.015 0.0426
Leishmania major modification methylase-like protein 0.0039 0.0125 0.0282
Schistosoma mansoni polybromo-1 0.0016 0.0015 0.0001
Loa Loa (eye worm) hypothetical protein 0.0179 0.0798 0.1229
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0031 0.009 0.0204
Loa Loa (eye worm) hypothetical protein 0.0022 0.0046 0.0061
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0025 0.0058 0.0044
Trypanosoma brucei ISWI complex protein 0.0018 0.0025 0.0059
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0245 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0125 0.0184
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0195 0.0873 0.1345
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0195 0.0873 0.086
Plasmodium falciparum heterochromatin protein 1 0.0022 0.0046 0.0066
Trichomonas vaginalis importin beta-1, putative 0.0049 0.0172 0.0256
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0235 0.1065 0.2557
Trypanosoma brucei unspecified product 0.0271 0.1243 0.2932
Entamoeba histolytica thioredoxin reductase, putative 0.0031 0.009 0.0261
Trichomonas vaginalis dullard protein, putative 0.0025 0.0057 0.0078
Toxoplasma gondii hypothetical protein 0.0144 0.0632 0.1943
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0342 0.1583 0.3823
Echinococcus granulosus importin subunit beta 1 0.006 0.0226 0.0212
Leishmania major DNA polymerase eta, putative 0.0621 0.2925 0.6895
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0082 0.0334 0.1503
Trypanosoma brucei DNA polymerase eta, putative 0.0621 0.2925 0.69
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0057 0.0119
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0022 0.0046 0.0097
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0031 0.009 0.0197
Echinococcus multilocularis Chromo domain 0.0022 0.0046 0.0031
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0025 0.0058 0.0135
Echinococcus multilocularis thioredoxin glutathione reductase 0.0347 0.1605 0.1593
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0053 0.0072
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0245 0.0231
Echinococcus multilocularis histone acetyltransferase MYST2 0.0107 0.0453 0.0439
Trypanosoma cruzi DNA damage repair protein, putative 0.0122 0.0525 0.1226
Giardia lamblia Kinase, PLK 0.0466 0.2179 0.677
Mycobacterium ulcerans DNA polymerase IV 0.0553 0.2596 0.4001
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0119 0.0508 0.0779
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0162 0.0716 0.2206
Loa Loa (eye worm) programmed cell death 8 0.0031 0.009 0.0129
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0121 0.0178
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0639 0.3009 0.4658
Trypanosoma cruzi DNA polymerase kappa, putative 0.0553 0.2596 0.6119
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0677 0.3192 0.7758
Echinococcus granulosus jumonji domain containing 1A 0.0025 0.0058 0.0043
Treponema pallidum exodeoxyribonuclease (exoA) 0.0055 0.0204 0.037
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0025 0.0057 0.0158
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0868 0.4108 1
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0195 0.0873 0.0861
Trichomonas vaginalis CAMK family protein kinase 0.0466 0.2179 0.3371
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0366 0.1697 0.1686
Echinococcus granulosus phd:f box containing protein 0.0025 0.0058 0.0043
Mycobacterium tuberculosis Probable reductase 0.0781 0.369 0.8976
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0029
Echinococcus granulosus peregrin 0.0035 0.0109 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0046 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0125 0.0184
Brugia malayi Disco-interacting protein 2 homolog 0.0076 0.0303 0.0461
Toxoplasma gondii ABC1 family protein 0.0037 0.0115 0.0315
Trypanosoma cruzi hypothetical protein, conserved 0.0122 0.0525 0.1226
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0061 0.0232 0.0351
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0035 0.0105 0.009
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0824 0.39 0.3891
Schistosoma mansoni flap endonuclease-1 0.0046 0.016 0.0146
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0054 0.0046
Mycobacterium ulcerans ferredoxin reductase 0.0031 0.009 0.0101
Trypanosoma cruzi polo-like protein kinase, putative 0.0466 0.2179 0.5133
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0031 0.009 0.0261
Echinococcus granulosus geminin 0.0165 0.0732 0.0719
Echinococcus granulosus lysine specific demethylase 5A 0.0103 0.0433 0.0419
Trypanosoma cruzi ISWI complex protein 0.0018 0.0025 0.0044
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0086 0.035 0.1054
Echinococcus multilocularis geminin 0.0165 0.0732 0.0719
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0031 0.009 0.0129
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0055 0.0204 0.0567
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0094 0.039 0.1762
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0031 0.009 0.017
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0433 0.202 0.4757
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0115 0.0231
Schistosoma mansoni phosphoglycerate kinase 0.0677 0.3192 0.3183
Echinococcus granulosus DNA methyltransferase 2, putative 0.0039 0.0125 0.0111
Leishmania major DNA polymerase kappa, putative 0.0433 0.202 0.4757
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0031 0.009 0.0261
Trypanosoma brucei DNA polymerase kappa, putative 0.0311 0.1433 0.338
Loa Loa (eye worm) hypothetical protein 0.0076 0.0303 0.0461
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0424 0.1974 0.4656
Treponema pallidum NADH oxidase 0.0119 0.0508 0.1349
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0237 0.0224
Entamoeba histolytica Flap nuclease, putative 0.0051 0.0183 0.0556
Leishmania major phosphoglycerate kinase C, glycosomal 0.0677 0.3192 0.7526
Trypanosoma brucei trypanothione reductase 0.0342 0.1583 0.3734
Brugia malayi hypothetical protein 0.0022 0.0046 0.0061
Trypanosoma cruzi DNA polymerase eta, putative 0.0621 0.2925 0.6895
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0115 0.014
Brugia malayi PHD-finger family protein 0.0028 0.0074 0.0106
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0086 0.035 0.0533
Brugia malayi Protein cec-1. 0.0022 0.0046 0.0061
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0044 0.015 0.0298
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0121 0.0178
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0121 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0306 0.0465
Loa Loa (eye worm) hypothetical protein 0.0022 0.0046 0.0061
Trichomonas vaginalis CAMK family protein kinase 0.0466 0.2179 0.3371
Schistosoma mansoni sulfide quinone reductase 0.0031 0.009 0.0076
Echinococcus granulosus JmjC domain containing protein 4 0.0025 0.0058 0.0043
Leishmania major DNA polymerase eta, putative 0.035 0.1621 0.3814
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0039 0.0044
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0031 0.009 0.0075
Loa Loa (eye worm) hypothetical protein 0.0017 0.002 0.0021
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0031 0.009 0.0261
Mycobacterium ulcerans glutamate synthase subunit beta 0.0031 0.009 0.0101
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0053 0.0038
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0031 0.009 0.017
Mycobacterium ulcerans hypothetical protein 0.0031 0.009 0.0101
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0031 0.009 0.0087
Echinococcus multilocularis chromobox protein 2 0.0022 0.0046 0.0031
Brugia malayi Thioredoxin reductase 0.0342 0.1583 0.2446
Trypanosoma brucei DNA polymerase kappa, putative 0.0553 0.2596 0.6125
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0195 0.0873 0.2048
Echinococcus granulosus polycomb protein SCMH1 0.0094 0.039 0.0376
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0054 0.0046
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0237 0.0224
Schistosoma mansoni ap endonuclease 0.0055 0.0204 0.0191
Echinococcus granulosus chromobox protein 1 0.0136 0.0594 0.058
Mycobacterium ulcerans hypothetical protein 0.0024 0.0054 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0553 0.2596 0.6125
Trypanosoma cruzi DNA damage repair protein, putative 0.0122 0.0525 0.1226
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0677 0.3192 0.4942
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0115 0.0231
Trichomonas vaginalis CAMK family protein kinase 0.0466 0.2179 0.3371
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0115 0.0231
Trichomonas vaginalis CAMK family protein kinase 0.0466 0.2179 0.3371
Trichomonas vaginalis DNA polymerase eta, putative 0.0553 0.2596 0.4018
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0119 0.0508 0.0494
Brugia malayi Bromodomain containing protein 0.0017 0.002 0.0021
Trypanosoma brucei polo-like protein kinase 0.0466 0.2179 0.514
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0466 0.2179 0.3371
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0091 0.0239
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0055 0.0204 0.0189
Loa Loa (eye worm) hypothetical protein 0.0107 0.0453 0.0693
Schistosoma mansoni serine/threonine protein kinase 0.0466 0.2179 0.2168
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0553 0.2596 0.4018
Leishmania major DNA damage repair protein, putative 0.0122 0.0525 0.1226
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0132 0.0195
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0115 0.014
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0895 0.4239 1
Echinococcus granulosus dna polymerase eta 0.0621 0.2925 0.2915
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0094 0.039 0.0377
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0031 0.009 0.0129
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0245 0.055
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0087 0.0357 0.0544
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0061 0.0232 0.0351
Trypanosoma cruzi DNA polymerase kappa, putative 0.0553 0.2596 0.6119
Toxoplasma gondii HEAT repeat-containing protein 0.006 0.0226 0.0665
Mycobacterium ulcerans hypothetical protein 0.0122 0.0525 0.0779
Plasmodium vivax importin-beta 2, putative 0.006 0.0226 0.0705
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0022 0.0046 0.0066
Plasmodium falciparum DNA repair protein REV1, putative 0.0122 0.0525 0.158
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0061 0.0232 0.0351
Mycobacterium ulcerans DNA polymerase IV 0.0553 0.2596 0.4001
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0031 0.009 0.0129
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0031 0.009 0.0129
Echinococcus multilocularis lysine specific demethylase 5A 0.0093 0.0386 0.0372
Echinococcus granulosus mixed lineage leukemia protein mll 0.0045 0.0153 0.0139
Loa Loa (eye worm) glutaminase 2 0.1355 0.6453 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0058 0.008
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0031 0.009 0.0129
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0152 0.0667 0.0653
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0152 0.0667 0.0653
Trichomonas vaginalis CAMK family protein kinase 0.0466 0.2179 0.3371
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0115 0.0101
Loa Loa (eye worm) hypothetical protein 0.0022 0.0046 0.0061
Entamoeba histolytica hypothetical protein 0.0022 0.0046 0.0124
Brugia malayi Flap endonuclease-1 0.0051 0.0183 0.0275
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0394 0.183 0.1819
Trichomonas vaginalis dullard protein, putative 0.0025 0.0057 0.0078
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0126 0.0543 0.1268
Trypanosoma brucei glucosidase, putative 0.0038 0.0121 0.0285
Plasmodium falciparum thioredoxin reductase 0.0342 0.1583 0.492
Brugia malayi mbt repeat family protein 0.0094 0.039 0.0596
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0025 0.0057 0.01
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0025 0.0057 0.0042
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0424 0.1974 0.4648
Mycobacterium ulcerans glutaminase 0.1355 0.6453 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0237 0.0223
Loa Loa (eye worm) hypothetical protein 0.0037 0.0115 0.0168
Trichomonas vaginalis ap endonuclease, putative 0.0055 0.0204 0.0307
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0032 0.0093 0.0078
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0025 0.0075
Schistosoma mansoni hypothetical protein 0.0024 0.0055 0.0042
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0115 0.0168
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0121 0.0106
Onchocerca volvulus Serine\/threonine kinase homolog 0.0466 0.2179 0.9969
Echinococcus multilocularis lysosomal alpha glucosidase 0.0171 0.0761 0.0747
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0025 0.0057 0.0175
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0022 0.0046 0.0097
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0054 0.0083
Echinococcus granulosus Chromo domain 0.0022 0.0046 0.0031
Brugia malayi Valyl-tRNA synthetase 0.0022 0.0046 0.0061
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0025 0.0057 0.0078
Brugia malayi CHD4 protein 0.0032 0.0093 0.0134
Loa Loa (eye worm) beta-lactamase 0.0037 0.0115 0.0168
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0022 0.0046 0.0066
Trypanosoma brucei DNA polymerase kappa, putative 0.0282 0.1292 0.3048
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0781 0.369 0.8976
Echinococcus multilocularis glutamate synthase 0.0031 0.009 0.0075
Giardia lamblia Histone acetyltransferase GCN5 0.0078 0.0315 0.0825
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0195 0.0873 0.2048
Trypanosoma brucei hypothetical protein, conserved 0.0122 0.0525 0.1239
Trypanosoma brucei phosphoglycerate kinase 0.0677 0.3192 0.7529
Brugia malayi ImpB/MucB/SamB family protein 0.0621 0.2925 0.4528
Loa Loa (eye worm) mbt repeat family protein 0.0094 0.039 0.0596
Brugia malayi glutamate synthase 0.0031 0.009 0.0129
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0037
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0249 0.1133 0.2661
Trichomonas vaginalis mercuric reductase, putative 0.0119 0.0508 0.0779
Mycobacterium ulcerans beta-lactamase 0.0037 0.0115 0.014
Echinococcus granulosus histone acetyltransferase KAT2B 0.0086 0.035 0.0335
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0031 0.009 0.017
Loa Loa (eye worm) thioredoxin reductase 0.0342 0.1583 0.2446
Schistosoma mansoni myelin transcription factor 1 myt1 0.0107 0.0453 0.044
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0237 0.0224
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0031 0.009 0.0101
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0031 0.009 0.0236
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0074 0.0061
Onchocerca volvulus 0.0022 0.0046 0.0181
Schistosoma mansoni kinase 0.0237 0.1077 0.1065
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0245 0.0342
Onchocerca volvulus 0.0468 0.2186 1
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0466 0.2179 0.2168
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0016 0.0046
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0677 0.3192 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.009 0.0129
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0029
Brugia malayi beta-lactamase family protein 0.0037 0.0115 0.0168
Brugia malayi Importin beta-1 subunit 0.006 0.0226 0.0341
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0115 0.0256
Loa Loa (eye worm) histone methyltransferase 0.0055 0.0204 0.0306
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0249 0.1133 0.2661
Schistosoma mansoni jumonji domain containing protein 0.0025 0.0058 0.0044
Onchocerca volvulus 0.0076 0.0303 0.1363
Trichomonas vaginalis chromobox protein, putative 0.0022 0.0046 0.0061
Brugia malayi glutaminase DH11.1 0.1355 0.6453 1
Brugia malayi jmjC domain containing protein 0.0025 0.0058 0.008
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0195 0.0873 0.206
Echinococcus granulosus histone acetyltransferase KAT2B 0.0283 0.1298 0.1285
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0153 0.0139
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0031 0.009 0.0075
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0119 0.0508 0.1199
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0054 0.0083
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0119 0.0508 0.0494
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0022 0.0046 0.0031
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0119 0.0508 0.1186
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0027 0.0067 0.0053
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0195 0.0873 0.2722
Echinococcus granulosus Chromobox protein 3 0.0022 0.0046 0.0031
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0031 0.009 0.0075
Schistosoma mansoni sex comb on midleg homolog 0.0094 0.039 0.0377
Brugia malayi Glycosyl hydrolases family 31 protein 0.0171 0.0761 0.117
Toxoplasma gondii hypothetical protein 0.0167 0.074 0.2283
Onchocerca volvulus 0.0085 0.0345 0.1552
Schistosoma mansoni bromodomain containing protein 0.0017 0.002 0.0006
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0677 0.3192 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0055 0.0204 0.0189
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.0039 0.0125 0.0318
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0054 0.0074
Brugia malayi jmjC domain containing protein 0.0152 0.0667 0.1025
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0119 0.0508 0.1186
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0044 0.015 0.0223
Plasmodium vivax DNA repair protein REV1, putative 0.0122 0.0525 0.1644
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0061 0.0232 0.0351
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0031 0.009 0.0261
Toxoplasma gondii DNA methyltransferase 2, putative 0.0039 0.0125 0.0349
Echinococcus multilocularis importin subunit beta 1 0.006 0.0226 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0125 0.0184
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0055 0.0204 0.0471
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0031 0.009 0.0236
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0031 0.009 0.0129
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0031 0.009 0.0211
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0006 0.0015
Schistosoma mansoni phosphatidylserine receptor 0.0025 0.0058 0.0044
Toxoplasma gondii NADPH-glutathione reductase 0.0119 0.0508 0.1553
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0054 0.0074
Plasmodium falciparum JmjC domain-containing protein, putative 0.0025 0.0058 0.0103
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0237 0.0701
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0115 0.0149
Echinococcus multilocularis zinc finger protein 0.0017 0.002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0025 0.0058 0.008
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0031 0.009 0.0236
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0039 0.0125 0.0111
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0031 0.009 0.0197
Onchocerca volvulus 0.0099 0.0414 0.1871
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0031 0.009 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.0311 0.1433 0.338
Echinococcus granulosus flap endonuclease 1 0.0051 0.0183 0.0169
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0119 0.0508 0.1349
Schistosoma mansoni rotamase 0.0032 0.0094 0.0081
Schistosoma mansoni chromobox protein 0.0136 0.0594 0.0581
Schistosoma mansoni glutamate synthase 0.0031 0.009 0.0076
Loa Loa (eye worm) glutathione reductase 0.0342 0.1583 0.2446
Brugia malayi jmjC domain containing protein 0.0025 0.0058 0.008
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0121 0.036
Brugia malayi SET domain containing protein 0.0024 0.0056 0.0077
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0677 0.3192 0.4942
Leishmania major hypothetical protein, conserved 0.0037 0.0115 0.0256
Trichomonas vaginalis hypothetical protein 0.0021 0.0039 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0433 0.202 0.4765
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0115 0.0168
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.015 0.034
Schistosoma mansoni glutamate synthase 0.0031 0.009 0.0076
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0051 0.0183 0.0418
Echinococcus granulosus expressed protein 0.0032 0.0094 0.008
Mycobacterium tuberculosis Conserved hypothetical protein 0.0394 0.183 0.4427
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0031 0.009 0.0278
Brugia malayi glutathione reductase 0.0342 0.1583 0.2446
Brugia malayi PHD-finger family protein 0.0019 0.003 0.0037
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0115 0.01
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0054 0.0113
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0119 0.0508 0.0752
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0031 0.009 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0125 0.0184
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0031 0.009 0.0087
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0055 0.0204 0.019
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0031 0.009 0.0211
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0031 0.009 0.0129
Giardia lamblia Flap structure-specific endonuclease 0.0051 0.0183 0.0404
Giardia lamblia Glutamate synthase 0.0031 0.009 0.0105
Trypanosoma brucei DNA polymerase IV, putative 0.0514 0.2406 0.5676
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0029
Brugia malayi polybromodomain protein 0.0016 0.0015 0.0013
Brugia malayi serine/threonine-protein kinase plk-2 0.0466 0.2179 0.3371
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0046 0.0061
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0394 0.183 0.1818
Treponema pallidum phosphoglycerate kinase 0.0677 0.3192 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0153 0.0139
Brugia malayi polk-prov protein 0.0282 0.1292 0.1994
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0029 0.0015
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0119 0.0508 0.0752
Schistosoma mansoni cpg binding protein 0.0247 0.1127 0.1115
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0895 0.4239 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0078 0.0315 0.0917
Brugia malayi RNA, U transporter 1 0.017 0.0756 0.1163
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0249 0.1133 0.2661
Loa Loa (eye worm) MBCTL1 0.0107 0.0453 0.0693
Trichomonas vaginalis hypothetical protein 0.0022 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0037 0.0115 0.0168
Entamoeba histolytica deoxycytidyl transferase, putative 0.0394 0.183 0.5725
Trypanosoma brucei DNA polymerase kappa, putative 0.0553 0.2596 0.6125
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0031 0.009 0.0236
Schistosoma mansoni myst-related protein 0.002 0.0036 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0553 0.2596 0.6125
Loa Loa (eye worm) hypothetical protein 0.0094 0.039 0.0596
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0115 0.0168
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0054 0.0198 0.0185
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0031 0.009 0.0197
Plasmodium falciparum zinc finger protein, putative 0.002 0.0036 0.0034
Schistosoma mansoni chromobox protein 0.0022 0.0046 0.0032
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0022 0.0046 0.0032
Loa Loa (eye worm) hypothetical protein 0.0037 0.0115 0.0168
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0119 0.0508 0.1186
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0031 0.009 0.0129
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0087 0.0357 0.0544

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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