Detailed information for compound 799064

Basic information

Technical information
  • TDR Targets ID: 799064
  • Name: 6-bromo-3-(4-chlorophenyl)-4-hydroxy-N-(3-met hylbutyl)-2-oxo-1H-quinazoline-4-carboxamide
  • MW: 466.756 | Formula: C20H21BrClN3O3
  • H donors: 3 H acceptors: 3 LogP: 4.03 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(CCNC(=O)C1(O)c2cc(Br)ccc2NC(=O)N1c1ccc(cc1)Cl)C
  • InChi: 1S/C20H21BrClN3O3/c1-12(2)9-10-23-18(26)20(28)16-11-13(21)3-8-17(16)24-19(27)25(20)15-6-4-14(22)5-7-15/h3-8,11-12,28H,9-10H2,1-2H3,(H,23,26)(H,24,27)
  • InChiKey: CZTBLPCAWJNOHY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 6-bromo-3-(4-chlorophenyl)-4-hydroxy-N-isopentyl-2-oxo-1H-quinazoline-4-carboxamide
  • 6-bromo-3-(4-chlorophenyl)-4-hydroxy-N-isoamyl-2-keto-1H-quinazoline-4-carboxamide
  • EU-0088310

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0079 0.0163
Brugia malayi steroid hormone receptor 0.0071 0.0209 0.0582
Loa Loa (eye worm) hypothetical protein 0.0034 0.0055 0.0077
Plasmodium falciparum calcium-dependent protein kinase 5 0.0039 0.0079 0.03
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0071 0.0209 0.02
Echinococcus granulosus peptidase Clp S14 family 0.0104 0.034 0.0533
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0325 0.15
Loa Loa (eye worm) hypothetical protein 0.0034 0.0055 0.0077
Brugia malayi Pyruvate kinase, M2 isozyme 0.0066 0.0188 0.0525
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0325 0.15
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.064 0.3044
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0158 0.0562 0.2646
Toxoplasma gondii histone lysine methyltransferase SET1 0.0167 0.0596 0.4304
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0044 0.0096 0.0276
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.0342 0.1019
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.027 0.1019 0.1628
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0114
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0066 0.0188 0.0202
Trypanosoma cruzi pyruvate kinase 2, putative 0.0066 0.0188 0.0556
Onchocerca volvulus 0.0233 0.0867 0.6706
Schistosoma mansoni cpg binding protein 0.0085 0.0266 0.0411
Brugia malayi beta-lactamase family protein 0.0334 0.1278 0.3561
Trypanosoma brucei glucose transporter, putative 0.0039 0.0076 0.0424
Schistosoma mansoni hypothetical protein 0.024 0.0896 0.1426
Echinococcus granulosus dnaJ subfamily B 0.1217 0.487 0.7826
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0125 0.0425 0.067
Trypanosoma brucei THT1 - hexose transporter, putative 0.0039 0.0076 0.0424
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.0753 0.1199
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0325 0.15
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0237 0.026
Trypanosoma cruzi polo-like protein kinase, putative 0.01 0.0325 0.0967
Leishmania major pyruvate kinase 0.0066 0.0188 0.0501
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0188 0.127
Schistosoma mansoni hypothetical protein 0.1217 0.487 0.7825
Schistosoma mansoni inositol transporter 0.0115 0.0388 0.0607
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0125 0.0425 0.0417
Trichomonas vaginalis ran, putative 0.0086 0.0269 0.1228
Trypanosoma cruzi pyruvate kinase 2, putative 0.0066 0.0188 0.0556
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.0039 0.0105
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0028 0.0031 0.0073
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0039 0.0079 0.0112
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0044 0.0096 0.0584
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0118 0.0397 0.1854
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0078 0.0237 0.1713
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0237 0.0579
Echinococcus multilocularis thioredoxin glutathione reductase 0.0086 0.0269 0.026
Mycobacterium tuberculosis Probable lipase LipE 0.0334 0.1278 0.1471
Brugia malayi Nuclear hormone receptor E75 0.0034 0.0055 0.0154
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0048 0.0133
Schistosoma mansoni kinase 0.0052 0.0131 0.0194
Schistosoma mansoni alpha-glucosidase 0.0285 0.1079 0.172
Onchocerca volvulus 0.0034 0.0055 0.0205
Brugia malayi hypothetical protein 0.0038 0.0072 0.02
Schistosoma mansoni hypothetical protein 0.0111 0.0371 0.058
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0044 0.0054
Schistosoma mansoni alpha-glucosidase 0.0285 0.1079 0.172
Loa Loa (eye worm) hypothetical protein 0.0078 0.0237 0.037
Echinococcus granulosus importin subunit beta 1 0.0145 0.0509 0.0804
Schistosoma mansoni beta-mannosidase 0.0171 0.0614 0.0972
Leishmania major glucose transporter, lmgt2 0.0039 0.0076 0.0153
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0079 0.0075
Loa Loa (eye worm) hypothetical protein 0.0034 0.0055 0.0077
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0111 0.0371 0.0362
Leishmania major fatty acid transporter protein-like protein 0.0824 0.3271 1
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0115 0.0388 0.0379
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0034 0.0055 0.0205
Plasmodium falciparum glutathione reductase 0.0086 0.0267 0.1214
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0071 0.0209 0.0324
Trypanosoma cruzi hexose transporter, putative 0.0039 0.0076 0.0215
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0022 0.0062
Schistosoma mansoni importin-beta 2 0.0027 0.003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0058 0.0155 0.0238
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0126 0.0531
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0117 0.0394 0.0385
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0231 0.1045
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0022 0.0054
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0037 0.007 0.0096
Schistosoma mansoni cpg binding protein 0.009 0.0286 0.0443
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0077 0.0231 0.0358
Echinococcus granulosus lipoxygenase domain containing protein 0.0059 0.0159 0.0242
Brugia malayi Pre-SET motif family protein 0.0205 0.0753 0.2097
Brugia malayi nuclear receptor RXR 0.0034 0.0055 0.0154
Trypanosoma cruzi importin beta-1 subunit, putative 0.0118 0.0397 0.1186
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0071 0.0209 0.0319
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.064 0.3044
Onchocerca volvulus 0.0059 0.0159 0.1039
Toxoplasma gondii propionate-CoA ligase 0.0078 0.0237 0.1614
Loa Loa (eye worm) hypothetical protein 0.007 0.0204 0.0316
Schistosoma mansoni lysyl-tRNA synthetase 0.0028 0.0031 0.0033
Schistosoma mansoni hypothetical protein 0.1549 0.6221 1
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0104 0.0342 0.2542
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0074 0.0218 0.1126
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0076 0.0284
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0034 0.0055 0.0046
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0039 0.0079 0.007
Schistosoma mansoni cpg binding protein 0.009 0.0286 0.0443
Echinococcus multilocularis translational activator gcn1 0.0027 0.003 0.0021
Schistosoma mansoni ap endonuclease 0.0077 0.0231 0.0355
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0079 0.0299
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0039 0.0041
Brugia malayi follicle stimulating hormone receptor 0.0256 0.0959 0.2671
Loa Loa (eye worm) hypothetical protein 0.0059 0.0159 0.0244
Loa Loa (eye worm) hypothetical protein 0.0071 0.0209 0.0324
Loa Loa (eye worm) PHD-finger family protein 0.0058 0.0155 0.0238
Echinococcus granulosus long chain fatty acid transport protein 4 0.0835 0.3315 0.5322
Echinococcus multilocularis lysosomal alpha glucosidase 0.0331 0.1267 0.1259
Echinococcus granulosus pyruvate kinase 0.0066 0.0188 0.0289
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0085 0.0245
Schistosoma mansoni peptidase Clp (S14 family) 0.0158 0.0562 0.0887
Entamoeba histolytica hypothetical protein 0.0452 0.1757 1
Echinococcus granulosus dna polymerase kappa 0.0039 0.0079 0.0112
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0044 0.0035
Schistosoma mansoni thyroid hormone receptor 0.0071 0.0209 0.0319
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0138 0.048 0.3646
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0074 0.0218 0.1126
Echinococcus granulosus transportin 1 0.0027 0.003 0.0034
Onchocerca volvulus 0.0078 0.0237 0.1664
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0079 0.0298
Mycobacterium ulcerans glutaminase 0.0266 0.1001 0.2725
Loa Loa (eye worm) hypothetical protein 0.0034 0.0055 0.0077
Echinococcus granulosus acetylcholinesterase 0.007 0.0204 0.0314
Loa Loa (eye worm) hypothetical protein 0.0078 0.0237 0.037
Loa Loa (eye worm) kap beta 3 protein 0.0027 0.003 0.0036
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0074 0.0218 0.0977
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0026 0.0026 0.0065
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0086 0.0269 0.7655
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0039 0.0105
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.003 0.0039 0.0045
Plasmodium falciparum phd finger protein, putative 0.0058 0.0155 0.0672
Toxoplasma gondii facilitative glucose transporter GT1 0.0125 0.0425 0.3022
Echinococcus multilocularis lipoxygenase domain containing protein 0.0059 0.0159 0.0151
Echinococcus multilocularis solute carrier family 5 0.0115 0.0388 0.0379
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0071 0.0209 0.0324
Echinococcus granulosus nuclear receptor nhr 48 0.0034 0.0055 0.0075
Echinococcus granulosus pyruvate kinase 0.0034 0.0057 0.0077
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0086 0.0269 0.1963
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0078 0.0237 0.0685
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0325 0.15
Schistosoma mansoni acetyl-CoA synthetase 0.0078 0.0237 0.0365
Mycobacterium ulcerans pyruvate kinase 0.0066 0.0188 0.0441
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0071 0.0209 0.0324
Echinococcus granulosus cpg binding protein 0.009 0.0286 0.0446
Brugia malayi Carboxylesterase family protein 0.007 0.0204 0.0568
Schistosoma mansoni transcription factor LCR-F1 0.0452 0.1757 0.2812
Schistosoma mansoni DNA polymerase eta 0.0039 0.0079 0.0109
Toxoplasma gondii pyruvate kinase PyK1 0.0066 0.0188 0.1246
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0041 0.0087 0.0122
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.003 0.006
Trypanosoma brucei DNA polymerase eta, putative 0.0039 0.0079 0.045
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0058 0.0155 0.0233
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0039 0.0079 0.03
Brugia malayi acetyltransferase, GNAT family protein 0.0149 0.0525 0.1462
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0097 0.0387
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0237 0.0662
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0117 0.0394 0.1018
Loa Loa (eye worm) hypothetical protein 0.0024 0.0016 0.0013
Loa Loa (eye worm) hypothetical protein 0.0037 0.007 0.0101
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0188 0.127
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0125 0.0524
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.1019 0.4893
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0048 0.0039
Trypanosoma brucei glucose transporter, putative 0.0039 0.0076 0.0424
Echinococcus granulosus ecdysone induced protein 78C 0.0071 0.0209 0.0322
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0029 0.0054
Brugia malayi Calcitonin receptor-like protein seb-1 0.0352 0.1349 0.3758
Plasmodium falciparum lysine--tRNA ligase 0.0028 0.0031 0.007
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0079 0.022
Schistosoma mansoni hypothetical protein 0.0111 0.0371 0.058
Trypanosoma brucei protein kinase, putative 0.0104 0.0342 0.2542
Leishmania major acetyl-CoA synthetase, putative 0.0078 0.0237 0.0652
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0039 0.0105
Brugia malayi GH02984p 0.0115 0.0388 0.108
Onchocerca volvulus 0.0078 0.0237 0.1664
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0237 0.0579
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0104 0.034 0.1
Loa Loa (eye worm) pyruvate kinase-PB 0.0046 0.0107 0.0159
Schistosoma mansoni hypothetical protein 0.0125 0.0425 0.0667
Trypanosoma cruzi polo-like protein kinase, putative 0.01 0.0325 0.0967
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.064 0.3044
Brugia malayi nuclear hormone receptor 0.0034 0.0055 0.0154
Brugia malayi nuclear hormone receptor 0.0071 0.0209 0.0582
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0158 0.0562 0.2646
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0079 0.045
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0237 0.026
Plasmodium vivax proline--tRNA ligase, putative 0.0044 0.0096 0.0382
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0071 0.0209 0.0582
Onchocerca volvulus 0.0086 0.0269 0.192
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.024 0.0896 0.0888
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.003 0.0021
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.0209 0.02
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0071 0.0209 0.0319
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0086 0.0269 0.1224
Toxoplasma gondii ABC1 family protein 0.0334 0.1278 0.9419
Echinococcus multilocularis PHD finger protein rhinoceros 0.0058 0.0155 0.0146
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0071 0.0209 0.0324
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0115 0.0388 0.0379
Loa Loa (eye worm) nuclear receptor NHR-67 0.0034 0.0055 0.0077
Echinococcus granulosus geminin 0.1078 0.4306 0.6917
Trypanosoma brucei pyruvate kinase 1 0.0066 0.0188 0.1322
Plasmodium falciparum calcium-dependent protein kinase 4 0.0039 0.0079 0.03
Brugia malayi nuclear receptor RXR 0.0038 0.0072 0.02
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0048 0.0067
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0824 0.3271 0.3789
Brugia malayi serine/threonine-protein kinase plk-2 0.01 0.0325 0.0904
Echinococcus multilocularis importin subunit beta 1 0.0145 0.0509 0.05
Loa Loa (eye worm) hypothetical protein 0.0078 0.0237 0.037
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0026 0.0022 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0071 0.0209 0.0324
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0022 0.0023
Toxoplasma gondii protein kinase, putative 0.0353 0.1356 1
Trichomonas vaginalis glycoside hydrolase, putative 0.0527 0.2064 1
Onchocerca volvulus 0.0334 0.1278 1
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.003 0.0039 0.0041
Plasmodium falciparum calcium-dependent protein kinase 2 0.0039 0.0079 0.03
Schistosoma mansoni lipoxygenase 0.0059 0.0159 0.0239
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.003 0.006
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0086 0.0269 0.0799
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0039 0.0079 0.0423
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0111 0.0371 0.0583
Schistosoma mansoni pyruvate kinase 0.0066 0.0188 0.0286
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0071 0.0209 0.0319
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.027 0.1019 0.2838
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0125 0.0524
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0055 0.0072
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0078 0.0237 0.0579
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0104 0.0342 0.0973
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0086 0.0269 0.0749
Leishmania major protein kinase, putative 0.0039 0.0079 0.0162
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0218 0.0644
Echinococcus multilocularis high affinity choline transporter 1 0.0115 0.0388 0.0379
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0237 0.0579
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.003 0.006
Echinococcus multilocularis pyruvate kinase 0.0066 0.0188 0.018
Giardia lamblia NADH oxidase lateral transfer candidate 0.003 0.0039 0.0246
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0342 0.1583
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0077 0.0231 0.0562
Schistosoma mansoni ran 0.0086 0.0269 0.0415
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0071 0.0209 0.02
Brugia malayi Carboxylesterase family protein 0.007 0.0204 0.0568
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0118 0.0397 0.1854
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0039 0.0079 0.0423
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0048 0.0149
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0071 0.0209 0.02
Leishmania major 4-coumarate:coa ligase-like protein 0.0078 0.0237 0.0652
Trypanosoma cruzi trypanothione reductase, putative 0.0086 0.0267 0.0793
Loa Loa (eye worm) hypothetical protein 0.0111 0.0371 0.0585
Echinococcus granulosus sodium:glucose cotransporter 2 0.0115 0.0388 0.061
Echinococcus multilocularis ecdysone induced protein 78C 0.0071 0.0209 0.02
Giardia lamblia Kinase, PLK 0.01 0.0325 0.9451
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.003 0.0077
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0125 0.0364
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0079 0.045
Leishmania major hypothetical protein, conserved 0.0051 0.0125 0.0305
Brugia malayi kap beta 3 protein 0.0027 0.003 0.0083
Entamoeba histolytica pyruvate kinase, putative 0.0046 0.0107 0.0487
Echinococcus multilocularis importin 5 0.0027 0.003 0.0021
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0071 0.0209 0.0319
Loa Loa (eye worm) acetylcholinesterase 1 0.007 0.0204 0.0316
Echinococcus granulosus RUN 0.0059 0.0159 0.0242
Echinococcus multilocularis peptidase Clp (S14 family) 0.0104 0.034 0.0331
Brugia malayi isocitrate dehydrogenase 0.0032 0.0048 0.0133
Brugia malayi jmjC domain containing protein 0.0191 0.0695 0.1935
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0158 0.0562 0.089
Trypanosoma brucei glucose transporter, putative 0.0039 0.0076 0.0424
Echinococcus granulosus lysosomal alpha glucosidase 0.0331 0.1267 0.2025
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0342 0.1583
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0037 0.007 0.0278
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0103
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0103
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0071 0.0209 0.0582
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0086 0.0269 0.042
Trichomonas vaginalis importin beta-1, putative 0.0118 0.0397 0.1854
Schistosoma mansoni hypothetical protein 0.1078 0.4306 0.6916
Schistosoma mansoni jumonji/arid domain-containing protein 0.0075 0.0225 0.0345
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0039 0.0079 0.0448
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0068 0.0193 0.0208
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.0007 0.002
Plasmodium falciparum mitogen-activated protein kinase 2 0.0203 0.0743 0.3525
Trypanosoma cruzi hypothetical protein, conserved 0.0334 0.1278 0.3849
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0071 0.0209 0.0582
Plasmodium falciparum calcium-dependent protein kinase 1 0.0039 0.0079 0.03
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0074 0.0218 0.0977
Schistosoma mansoni rab6-interacting 0.0059 0.0159 0.0239
Onchocerca volvulus 0.0334 0.1278 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0048 0.0039
Trypanosoma brucei importin beta-1 subunit, putative 0.0145 0.0509 0.3872
Entamoeba histolytica serine/threonine protein kinase, putative 0.01 0.0325 0.1743
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0071 0.0209 0.0324
Mycobacterium tuberculosis Conserved protein 0.0334 0.1278 0.1471
Giardia lamblia Pyruvate kinase 0.0034 0.0057 0.0821
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0078 0.0237 0.0579
Trichomonas vaginalis set domain proteins, putative 0.0233 0.0867 0.4151
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0082 0.1624
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0125 0.0425 0.067
Trypanosoma cruzi hexose transporter 0.0039 0.0076 0.0215
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0034 0.0055 0.0205
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.0835 0.3315 1
Trichomonas vaginalis D-aminoacylase, putative 0.0334 0.1278 0.6161
Brugia malayi Steroid receptor seven-up type 2 0.0071 0.0209 0.0582
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0085 0.0502
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0028 0.0031 0.0068
Schistosoma mansoni glucose transport protein 0.0125 0.0425 0.0667
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0155 0.0998
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0079 0.0225
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0097 0.0558
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0037 0.007 0.0196
Loa Loa (eye worm) hypothetical protein 0.0051 0.0125 0.0188
Echinococcus multilocularis transportin 1 0.0027 0.003 0.0021
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0078 0.0237 0.0579
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0078 0.0237 0.026
Trichomonas vaginalis penicillin-binding protein, putative 0.0334 0.1278 0.6161
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0079 0.007
Loa Loa (eye worm) hypothetical protein 0.0352 0.1349 0.2159
Trypanosoma brucei glucose transporter, putative 0.0039 0.0076 0.0424
Echinococcus multilocularis geminin 0.1078 0.4306 0.43
Echinococcus multilocularis beta LACTamase domain containing family member 0.0334 0.1278 0.1271
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.0508 0.0803
Echinococcus granulosus high affinity choline transporter 1 0.0115 0.0388 0.061
Trichomonas vaginalis antibiotic synthetase, putative 0.0078 0.0237 0.1075
Loa Loa (eye worm) hypothetical protein 0.0318 0.1211 0.1936
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0077 0.0231 0.0223
Trichomonas vaginalis maltase-glucoamylase, putative 0.0027 0.003 0.006
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0072 0.02
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0218 0.0977
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0039 0.0079 0.03
Brugia malayi CXXC zinc finger family protein 0.0085 0.0266 0.0741
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0256 0.0959 0.1531
Leishmania major glucose transporter, lmgt3 0.0039 0.0076 0.0153
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.0835 0.3315 1
Trypanosoma brucei glucose transporter 2A 0.0039 0.0076 0.0424
Echinococcus granulosus thyroid hormone receptor alpha 0.0034 0.0055 0.0075
Trichomonas vaginalis glucose transporter, putative 0.0039 0.0076 0.0284
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0078 0.0237 0.0579
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0028 0.0031 0.0052
Echinococcus granulosus GPCR family 2 0.0111 0.0371 0.0583
Loa Loa (eye worm) hypothetical protein 0.0071 0.0209 0.0324
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.024 0.0896 0.2497
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0079 0.045
Brugia malayi Cam kinase protein 1 0.0039 0.0079 0.0219
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0679 0.3234
Schistosoma mansoni hypothetical protein 0.0111 0.0371 0.058
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0078 0.0237 0.026
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0071 0.0209 0.1435
Brugia malayi Pyruvate kinase, muscle isozyme 0.0066 0.0188 0.0525
Trichomonas vaginalis pyruvate kinase, putative 0.0066 0.0188 0.0835
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0078 0.0237 0.0368
Brugia malayi nuclear receptor NHR-88 0.0071 0.0209 0.0582
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0071 0.0209 0.0582
Schistosoma mansoni pyruvate kinase 0.0034 0.0057 0.0074
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0237 0.026
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0024 0.0015 0.0009
Loa Loa (eye worm) hypothetical protein 0.0034 0.0055 0.0077
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0078 0.0237 0.026
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0158 0.0562 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0217 0.0802 0.0917
Trichomonas vaginalis D-aminoacylase, putative 0.0334 0.1278 0.6161
Toxoplasma gondii hypothetical protein 0.0054 0.014 0.0882
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0039 0.0105
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0048 0.0039
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0125 0.0768
Leishmania major acetoin dehydrogenase e3 component-like protein 0.003 0.0039 0.0041
Entamoeba histolytica hypothetical protein 0.0452 0.1757 1
Schistosoma mansoni nuclear hormone receptor 0.0071 0.0209 0.0319
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0079 0.045
Loa Loa (eye worm) hypothetical protein 0.0334 0.1278 0.2045
Brugia malayi Thioredoxin reductase 0.0086 0.0267 0.0744
Entamoeba histolytica hypothetical protein 0.0118 0.0397 0.216
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0078 0.0237 0.0685
Trichomonas vaginalis glutaminase, putative 0.0266 0.1001 0.4805
Echinococcus multilocularis General substrate transporter 0.0107 0.0354 0.0345
Loa Loa (eye worm) steroid hormone receptor 0.0071 0.0209 0.0324
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0055 0.0072
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0039 0.0079 0.0112
Brugia malayi Glycosyl hydrolases family 31 protein 0.0074 0.0218 0.0606
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0054 0.014 0.193
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0071 0.0209 0.0324
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0334 0.1278 0.1471
Plasmodium vivax hypothetical protein, conserved 0.0334 0.1278 0.6128
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0078 0.0237 0.0579
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0452 0.1757 0.1749
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.1019 0.4893
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.003 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0071 0.0209 0.0582
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0218 0.0644
Brugia malayi tailless protein 0.0034 0.0055 0.0154
Onchocerca volvulus Protein ultraspiracle homolog 0.0071 0.0209 0.1435
Mycobacterium ulcerans hypothetical protein 0.0078 0.0237 0.0579
Brugia malayi lysyl-tRNA synthetase 0.0028 0.0031 0.0088
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0086 0.0269 0.1849
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0079 0.0326
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.064 0.3044
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0044 0.0054
Loa Loa (eye worm) hypothetical protein 0.0046 0.0107 0.0159
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0079 0.045
Plasmodium vivax glutathione reductase, putative 0.0086 0.0267 0.1214
Plasmodium falciparum LCCL domain-containing protein 0.0059 0.0159 0.0692
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1549 0.6221 1
Echinococcus granulosus translational activator gcn1 0.0027 0.003 0.0034
Loa Loa (eye worm) hypothetical protein 0.0066 0.0188 0.0291
Leishmania major glucose transporter/membrane transporter D2, putative 0.0039 0.0076 0.0153
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0071 0.0209 0.0582
Trypanosoma brucei polo-like protein kinase 0.01 0.0325 0.2407
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0079 0.045
Echinococcus multilocularis serine protein kinase ATM 0.0026 0.0022 0.0013
Echinococcus granulosus jumonji domain containing protein 0.0081 0.0248 0.0385
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0103
Schistosoma mansoni zinc finger protein 0.0034 0.0055 0.0072
Echinococcus granulosus importin 5 0.0027 0.003 0.0034
Schistosoma mansoni nuclear receptor 0.0034 0.0055 0.0072
Giardia lamblia Pyruvate kinase 0.0066 0.0188 0.506
Echinococcus granulosus mitogen activated protein kinase 0.0104 0.0342 0.0535
Plasmodium falciparum transportin 0.0027 0.003 0.0063
Trypanosoma brucei THT1 - hexose transporter, putative 0.0039 0.0076 0.0424
Onchocerca volvulus 0.0059 0.0159 0.1039
Schistosoma mansoni rab6-interacting 0.0059 0.0159 0.0239
Echinococcus multilocularis dna polymerase eta 0.0039 0.0079 0.007
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0342 0.0533
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0071 0.0209 0.0319
Schistosoma mansoni hypothetical protein 0.0111 0.0371 0.058
Onchocerca volvulus 0.0078 0.0237 0.1664
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0071 0.0209 0.0322
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0078 0.0237 0.1614
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0077 0.0231 0.6448
Entamoeba histolytica acyl-CoA synthetase, putative 0.0078 0.0237 0.1241
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0079 0.045
Leishmania major trypanothione reductase 0.0086 0.0267 0.0743
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0048 0.0202
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.003 0.0039 0.0107
Trichomonas vaginalis glucose transporter, putative 0.0039 0.0076 0.0284
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.1019 0.4893
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0079 0.045
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.003 0.0039 0.0048
Loa Loa (eye worm) latrophilin receptor protein 2 0.0111 0.0371 0.0585
Brugia malayi hypothetical protein 0.0059 0.0159 0.0444
Trypanosoma brucei glucose transporter, putative 0.0039 0.0076 0.0424
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0158 0.0562 0.4044
Brugia malayi exodeoxyribonuclease III family protein 0.0077 0.0231 0.0645
Toxoplasma gondii HEAT repeat-containing protein 0.0027 0.003 0.0058
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0203 0.0743 0.5402
Echinococcus multilocularis pyruvate kinase 0.0034 0.0057 0.0048
Plasmodium vivax CDK-related protein kinase 6, putative 0.053 0.2075 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0042 0.0055
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0334 0.1278 0.1471
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.003 0.0039 0.0021
Trypanosoma brucei glycosyl hydrolase-like protein 0.0027 0.003 0.006
Loa Loa (eye worm) hypothetical protein 0.0071 0.0209 0.0324
Schistosoma mansoni ran 0.0086 0.0269 0.0415
Loa Loa (eye worm) hypothetical protein 0.0078 0.0237 0.037
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0203 0.0743 0.3525
Brugia malayi glutathione reductase 0.0086 0.0267 0.0744
Echinococcus granulosus sodium:glucose cotransporter 0.0115 0.0388 0.061
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0078 0.0237 0.0685
Loa Loa (eye worm) hypothetical protein 0.0071 0.0209 0.0324
Echinococcus multilocularis snurportin 1 0.1549 0.6221 0.6218
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0071 0.0209 0.0582
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0039 0.0079 0.007
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0122 0.0355
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0054 0.014 0.0385
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.1019 0.4893
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0158 0.0562 1
Entamoeba histolytica hypothetical protein 0.0452 0.1757 1
Schistosoma mansoni hypothetical protein 0.0059 0.0159 0.0239
Onchocerca volvulus 0.0115 0.0388 0.2867
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0237 0.0579
Echinococcus multilocularis long chain fatty acid transport protein 4 0.0835 0.3315 0.3309
Plasmodium falciparum pyruvate kinase 2 0.0034 0.0057 0.0194
Trypanosoma brucei importin beta-1 subunit, putative 0.0145 0.0509 0.3872
Schistosoma mansoni hypothetical protein 0.0058 0.0155 0.0233
Loa Loa (eye worm) nuclear hormone receptor 0.0034 0.0055 0.0077
Trichomonas vaginalis pyruvate kinase, putative 0.0066 0.0188 0.0835
Echinococcus granulosus pyruvate kinase 0.0034 0.0057 0.0077
Mycobacterium ulcerans lipase LipD 0.0334 0.1278 0.3504
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0079 0.0109
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.064 0.3044
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0011 0.0003
Entamoeba histolytica acyl-coA synthetase, putative 0.0078 0.0237 0.1241
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0104 0.0342 0.0537
Leishmania major DNA polymerase kappa, putative 0.0039 0.0079 0.0163
Brugia malayi Probable ClpP-like protease 0.0158 0.0562 0.1564
Brugia malayi beta-lactamase family protein 0.0334 0.1278 0.3561
Brugia malayi PHD-finger family protein 0.0058 0.0155 0.0433
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0334 0.1278 0.3504
Echinococcus granulosus peregrin 0.0062 0.017 0.026
Echinococcus multilocularis mitogen activated protein kinase 0.0104 0.0342 0.0333
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.01 0.0325 0.0921
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0039 0.0079 0.007
Brugia malayi latrophilin 2 splice variant baaae 0.024 0.0896 0.2497
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0149 0.0525 0.0828
Loa Loa (eye worm) hypothetical protein 0.0037 0.007 0.0101
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0039 0.0105
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0076 0.0284
Brugia malayi hypothetical protein 0.0034 0.0055 0.0154
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0126 0.0531
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0078 0.0237 0.026
Loa Loa (eye worm) acetyltransferase 0.0149 0.0525 0.0833
Brugia malayi MH2 domain containing protein 0.0257 0.0963 0.2683
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0034 0.0055 0.0075
Leishmania major hypothetical protein, conserved 0.0027 0.003 0.0013
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0078 0.0237 0.026
Loa Loa (eye worm) beta-glucuronidase 0.0489 0.1907 0.3057
Brugia malayi nuclear hormone receptor family member nhr-6 0.0034 0.0055 0.0154
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0034 0.0055 0.0072
Schistosoma mansoni loxhd1 0.0059 0.0159 0.0239
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0034 0.0055 0.0046
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0078 0.0237 0.1241
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0039 0.0105
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0125 0.0524
Giardia lamblia Prolyl-tRNA synthetase 0.0037 0.007 0.1256
Leishmania major hypothetical protein, conserved 0.0334 0.1278 0.386
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0104 0.0342 0.1019
Loa Loa (eye worm) hypothetical protein 0.0034 0.0055 0.0077
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.003 0.0039 0.0107
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0125 0.0816
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0158 0.0562 1
Plasmodium falciparum hexose transporter 0.0125 0.0425 0.1984
Schistosoma mansoni glutaminase 0.0266 0.1001 0.1594
Trypanosoma brucei glucosidase, putative 0.0074 0.0218 0.1555
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0033 0.0038
Trypanosoma brucei trypanothione reductase 0.0086 0.0267 0.1948
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0086 0.0269 0.026
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.003 0.0034
Echinococcus granulosus thioredoxin glutathione reductase 0.0086 0.0269 0.0419
Echinococcus multilocularis dnaJ subfamily B 0.1217 0.487 0.4866
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0078 0.0237 0.0705
Brugia malayi Doublecortin family protein 0.0059 0.0159 0.0444
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0044 0.0167
Loa Loa (eye worm) hypothetical protein 0.007 0.0204 0.0316
Onchocerca volvulus 0.0192 0.0698 0.5354
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0125 0.0425 0.0417
Echinococcus multilocularis cpg binding protein 0.009 0.0286 0.0277
Schistosoma mansoni glucose transport protein 0.0125 0.0425 0.0667
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0325 0.15
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0034 0.0055 0.0154
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0076 0.0284
Echinococcus granulosus Polycystic kidney disease protein 0.0059 0.0159 0.0242
Schistosoma mansoni coup transcription factor 0.0071 0.0209 0.0319
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0078 0.0237 0.0662
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0188 0.0291
Brugia malayi Glycosyl hydrolases family 2, sugar binding domain containing protein 0.0503 0.1965 0.5473
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0071 0.0209 0.0322
Loa Loa (eye worm) hypothetical protein 0.0078 0.0237 0.037
Echinococcus granulosus pyruvate kinase 0.0066 0.0188 0.0289
Echinococcus multilocularis carboxylesterase 5A 0.007 0.0204 0.0195
Loa Loa (eye worm) beta-lactamase 0.0334 0.1278 0.2045
Toxoplasma gondii thioredoxin reductase 0.0086 0.0267 0.1834
Echinococcus granulosus General substrate transporter 0.0107 0.0354 0.0555
Mycobacterium leprae Probable lipase LipE 0.0334 0.1278 0.3882
Echinococcus granulosus lysine specific demethylase 5A 0.0075 0.0225 0.0348
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0011 0.0002
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0044 0.0096 0.0215
Brugia malayi manba-prov protein 0.0171 0.0614 0.1711
Loa Loa (eye worm) hypothetical protein 0.0086 0.0268 0.042
Trichomonas vaginalis glutathione reductase, putative 0.003 0.0039 0.0105
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0125 0.0425 0.0417
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0103
Toxoplasma gondii pyruvate kinase PyKII 0.0034 0.0057 0.026
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0104 0.0342 0.0973
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0218 0.0977
Brugia malayi Glycosyl hydrolases family 31 protein 0.0027 0.003 0.0083
Loa Loa (eye worm) glutathione reductase 0.0086 0.0267 0.0417
Schistosoma mansoni high-affinity choline transporter 0.0115 0.0388 0.0607
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.0034 0.0055 0.0077
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0182 0.066 0.1046
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0237 0.0579
Schistosoma mansoni steroid hormone receptor ad4bp 0.0071 0.0209 0.0319
Loa Loa (eye worm) hypothetical protein 0.0034 0.0055 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0079 0.045
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0452 0.1757 0.2814
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0218 0.0977
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0125 0.0425 0.0417
Brugia malayi hypothetical protein 0.0034 0.0055 0.0154
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0077 0.0231 0.1665
Trichomonas vaginalis sugar transporter, putative 0.0039 0.0076 0.0284
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.1019 0.4893
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0048 0.0131
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0231 0.1042
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0109 0.0362 0.057
Schistosoma mansoni thyroid hormone receptor 0.0071 0.0209 0.0319
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0195 0.0714 0.0814
Schistosoma mansoni sodium/solute symporter 0.0115 0.0388 0.0607
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.024 0.0896 0.0888
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0085 0.0245
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0078 0.0237 0.1713
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0117 0.0394 0.0441
Echinococcus multilocularis peregrin 0.0062 0.017 0.0161
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0054 0.014 0.0597
Echinococcus granulosus calcium dependent protein kinase 0.0036 0.0064 0.0088
Plasmodium vivax pyruvate kinase 2, putative 0.0034 0.0057 0.0194
Mycobacterium tuberculosis Possible penicillin-binding protein 0.2135 0.8608 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0034 0.0055 0.0077
Brugia malayi Sugar transporter family protein 0.0125 0.0425 0.1185
Echinococcus granulosus Nuclear hormone receptor HR96 0.0034 0.0055 0.0075
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.01 0.0325 0.051
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0071 0.0209 0.02
Echinococcus granulosus dna polymerase eta 0.0039 0.0079 0.0112
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0034 0.0055 0.0046
Plasmodium vivax hexose transporter 0.0125 0.0425 0.1984
Echinococcus multilocularis pyruvate kinase 0.0034 0.0057 0.0048
Trichomonas vaginalis beta-galactosidase, putative 0.0527 0.2064 1
Echinococcus multilocularis pyruvate kinase 0.0052 0.0131 0.0123
Echinococcus granulosus carboxylesterase 5A 0.007 0.0204 0.0314
Schistosoma mansoni alpha glucosidase 0.0074 0.0218 0.0333
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0217 0.0802 0.242
Brugia malayi hypothetical protein 0.0059 0.0159 0.0444
Mycobacterium leprae conserved hypothetical protein 0.0334 0.1278 0.3882
Brugia malayi PHD-finger family protein 0.0024 0.0016 0.0043
Trichomonas vaginalis D-aminoacylase, putative 0.0334 0.1278 0.6161
Plasmodium falciparum protein kinase 7 0.0353 0.1356 0.6505
Brugia malayi Glycosyl hydrolases family 31 protein 0.0331 0.1267 0.3529
Giardia lamblia PHD finger protein 15 0.0058 0.0155 0.3995
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0115 0.0388 0.061
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0103
Toxoplasma gondii hypothetical protein 0.0047 0.011 0.0657
Entamoeba histolytica hypothetical protein 0.0028 0.0031 0.0053
Brugia malayi Latrophilin receptor protein 2 0.0111 0.0371 0.1034
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0031 0.0045 0.0178
Leishmania major glucose transporter, lmgt1 0.0039 0.0076 0.0153
Loa Loa (eye worm) hypothetical protein 0.0115 0.0388 0.0612
Schistosoma mansoni RAR-like nuclear receptor 0.0071 0.0209 0.0319
Brugia malayi hypothetical protein 0.0086 0.0268 0.0748
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.0342 0.1019
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0334 0.1278 0.2041
Leishmania major GTP-binding protein, putative 0.0086 0.0269 0.0749
Echinococcus granulosus Nuclear hormone receptor HR96 0.0034 0.0055 0.0075
Loa Loa (eye worm) hypothetical protein 0.0071 0.0209 0.0324
Trypanosoma brucei glucose transporter, putative 0.0039 0.0076 0.0424
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0078 0.0237 0.026
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0902 0.359 0.5765
Brugia malayi hypothetical protein 0.0452 0.1757 0.4894
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0077 0.0231 0.0634
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0079 0.0133
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0039 0.0041
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.1106 0.3327
Brugia malayi hypothetical protein 0.0051 0.0125 0.0347
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.003 0.0039 0.0107
Echinococcus granulosus solute carrier family 5 0.0115 0.0388 0.061
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0896 0.1426
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0125 0.0364
Loa Loa (eye worm) MH2 domain-containing protein 0.0257 0.0963 0.1538
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0237 0.0662
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.048 0.1401
Schistosoma mansoni glucose transport protein 0.0125 0.0425 0.0667
Brugia malayi Pre-SET motif family protein 0.0031 0.0044 0.0124
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0191 0.0695 0.1104
Mycobacterium tuberculosis Conserved protein 0.0334 0.1278 0.1471
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0071 0.0209 0.0582
Echinococcus multilocularis acetylcholinesterase 0.007 0.0204 0.0195
Schistosoma mansoni nuclear receptor 0.0034 0.0055 0.0072
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0039 0.0079 0.0112
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0195 0.0714 0.0814
Brugia malayi ecdysone receptor 0.0034 0.0055 0.0154
Trichomonas vaginalis sucrase-isomaltase, putative 0.0074 0.0218 0.0977
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0074 0.0218 0.1464
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0078 0.0237 0.037
Loa Loa (eye worm) histone methyltransferase 0.0028 0.003 0.0036
Loa Loa (eye worm) hypothetical protein 0.0034 0.0055 0.0077
Brugia malayi F/Y-rich N-terminus family protein 0.0046 0.0106 0.0296
Schistosoma mansoni inositol transporter 0.0115 0.0388 0.0607
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0342 0.1583
Loa Loa (eye worm) hypothetical protein 0.0115 0.0388 0.0612
Echinococcus multilocularis lipoxygenase domain containing protein 0.0059 0.0159 0.0151
Loa Loa (eye worm) hypothetical protein 0.0031 0.0044 0.0059
Leishmania major glycosyl hydrolase-like protein 0.0027 0.003 0.0012
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0237 0.0579
Entamoeba histolytica Ran family GTPase 0.0086 0.0269 0.1422
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0044 0.0054
Brugia malayi Nuclear hormone receptor E75 0.0034 0.0055 0.0154
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0037 0.007 0.0099
Schistosoma mansoni protein kinase 0.0039 0.0079 0.0109
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0097 0.0558
Plasmodium vivax multidomain scavenger receptor, putative 0.0059 0.0159 0.0692
Echinococcus multilocularis nuclear receptor nhr 48 0.0034 0.0055 0.0046
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0044 0.0096 0.0276
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0079 0.0133
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0078 0.0237 0.0229
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0079 0.0075
Loa Loa (eye worm) hypothetical protein 0.0027 0.003 0.0035
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.024 0.0896 0.143
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0896 0.1426
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0078 0.0237 0.0579
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0195 0.0714 0.0814
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0037 0.007 0.0172
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.003 0.0039 0.0134
Brugia malayi Nuclear hormone receptor-like 1 0.0071 0.0209 0.0582
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0191 0.0695 0.0686
Treponema pallidum exodeoxyribonuclease (exoA) 0.0077 0.0231 0.3681
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0078 0.0237 0.0705
Loa Loa (eye worm) hypothetical protein 0.0086 0.0268 0.042
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0158 0.0562 0.149
Echinococcus granulosus sodium:myo inositol cotransporter 0.0115 0.0388 0.061
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0048 0.0039
Entamoeba histolytica acyl-CoA synthetase, putative 0.0078 0.0237 0.1241
Onchocerca volvulus Serine\/threonine kinase homolog 0.01 0.0325 0.2361
Schistosoma mansoni eyes absent homolog 0.0086 0.0268 0.0415
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0038 0.0072 0.0063
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0048 0.0149
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0078 0.0237 0.0662
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0076 0.0284
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0117 0.0394 0.1134
Loa Loa (eye worm) transcription factor SMAD2 0.0257 0.0963 0.1538
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0237 0.0579
Mycobacterium ulcerans beta-lactamase 0.0334 0.1278 0.3504
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.1019 0.4893
Brugia malayi RNA, U transporter 1 0.0412 0.1597 0.4449
Loa Loa (eye worm) hypothetical protein 0.0071 0.0209 0.0324
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0086 0.0267 0.0294
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0079 0.0299
Schistosoma mansoni protein kinase 0.0039 0.0079 0.0109
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0079 0.007
Echinococcus granulosus snurportin 1 0.1549 0.6221 1
Trypanosoma brucei unspecified product 0.0039 0.0079 0.045
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0039 0.0079 0.0112
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0079 0.0225
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0078 0.0237 0.0685
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0082 0.0315
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0039 0.0079 0.007
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0104 0.0342 0.2394
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0028 0.0031 0.0082
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.003 0.0039 0.0144
Giardia lamblia DINP protein human, muc B family 0.0039 0.0079 0.1527
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0237 0.026
Leishmania major mitochondrial DNA polymerase beta 0.0292 0.1106 0.3328
Brugia malayi orphan nuclear receptor NR2E1 0.0034 0.0055 0.0154
Entamoeba histolytica protein kinase, putative 0.0039 0.0079 0.0325
Loa Loa (eye worm) hypothetical protein 0.0059 0.0159 0.0244
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0078 0.0237 0.0579
Chlamydia trachomatis pyruvate kinase 0.0066 0.0188 0.296
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.003 0.0039 0.003
Mycobacterium tuberculosis Probable oxidoreductase 0.0217 0.0802 0.0917
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0158 0.0562 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.003 0.006
Loa Loa (eye worm) importin-beta domain-containing protein 0.0027 0.003 0.0036
Plasmodium vivax pyruvate kinase, putative 0.0066 0.0188 0.0833
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0125 0.0425 0.067
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0155 0.0998
Schistosoma mansoni ap endonuclease 0.0077 0.0231 0.0355
Brugia malayi jmjC domain containing protein 0.0075 0.0225 0.0627
Echinococcus multilocularis FTZ F1 alpha 0.0071 0.0209 0.02
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0097 0.0141
Onchocerca volvulus Bile acid receptor homolog 0.0071 0.0209 0.1435
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0679 0.3234
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0039 0.0134
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0231 0.1045
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0071 0.0209 0.0582
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0352 0.1349 0.3758
Mycobacterium tuberculosis Probable hydrolase 0.0334 0.1278 0.1471
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0325 0.15
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0077 0.0231 0.0686
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0079 0.022
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0158 0.0562 0.1681
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0079 0.0225
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0195 0.0714 0.0814
Echinococcus granulosus lipoxygenase domain containing protein 0.0059 0.0159 0.0242
Loa Loa (eye worm) glutaminase 2 0.0266 0.1001 0.1599
Leishmania major DNA polymerase eta, putative 0.0039 0.0079 0.0163
Echinococcus granulosus GTP binding nuclear protein Ran 0.0086 0.0269 0.0418
Onchocerca volvulus 0.0334 0.1278 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.0209 0.0322
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0078 0.0237 0.0579
Trypanosoma cruzi hexose transporter, putative 0.0039 0.0076 0.0215
Plasmodium vivax acetyl-CoA synthetase, putative 0.0078 0.0237 0.1071
Brugia malayi nuclear hormone receptor family member odr-7 0.0034 0.0055 0.0154
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0077 0.0231 0.0253
Plasmodium falciparum thioredoxin reductase 0.0086 0.0267 0.1214
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0342 0.1583
Echinococcus multilocularis calcium dependent protein kinase 0.0036 0.0064 0.0055
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0054 0.014 0.0597
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0077 0.0231 0.036
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0077 0.0231 0.0686
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0325 0.15
Echinococcus multilocularis lysine specific demethylase 5A 0.0071 0.0205 0.0196
Loa Loa (eye worm) hypothetical protein 0.0071 0.0209 0.0324
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0034 0.0055 0.0046
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0079 0.0225
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0231 0.1042
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0071 0.0209 0.0582
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.064 0.3044
Trichomonas vaginalis conserved hypothetical protein 0.0125 0.0425 0.1993
Brugia malayi conserved hypotetical protein 0.0034 0.0055 0.0154
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0086 0.0269 0.0799
Echinococcus granulosus PHD finger protein rhinoceros 0.0058 0.0155 0.0236
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0038 0.0072 0.0098
Schistosoma mansoni FFA transport protein 0.0835 0.3315 0.532
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0071 0.0209 0.0319
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.007 0.0204 0.0311
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0071 0.0209 0.0322
Mycobacterium leprae Probable pyruvate kinase PykA 0.0066 0.0188 0.0534
Loa Loa (eye worm) hypothetical protein 0.0158 0.0562 0.0892
Echinococcus multilocularis thyroid hormone receptor alpha 0.0071 0.0209 0.02
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0039 0.0105
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.024 0.0896 0.1429
Trypanosoma brucei unspecified product 0.0027 0.0029 0.0054
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0111 0.0371 0.0583
Leishmania major lysyl-tRNA synthetase, putative 0.0028 0.0031 0.0017
Trypanosoma cruzi hypothetical protein, conserved 0.0334 0.1278 0.3849
Echinococcus granulosus FTZ F1 alpha 0.0071 0.0209 0.0322
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0071 0.0209 0.0582
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0125 0.0425 0.067
Mycobacterium leprae possible long-chain acyl-CoA synthase 0.0824 0.3271 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0218 0.0977
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0117 0.0394 0.1097
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0048 0.0131
Trypanosoma cruzi hexose transporter, putative 0.0039 0.0076 0.0215
Onchocerca volvulus 0.0031 0.0044 0.0118
Loa Loa (eye worm) carboxylesterase 0.007 0.0204 0.0316
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.0007 0.002
Trypanosoma brucei pyruvate kinase 1, putative 0.0066 0.0188 0.1322
Onchocerca volvulus Glucosylceramidase homolog 0.0177 0.064 0.4891
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0086 0.0269 0.1224
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0071 0.0209 0.0322
Loa Loa (eye worm) hypothetical protein 0.0071 0.0209 0.0324
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0039 0.0105
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0292 0.1106 0.8626
Plasmodium falciparum thioredoxin reductase 0.003 0.0039 0.0107
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0237 0.0579
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0078 0.0237 0.0579
Schistosoma mansoni lysyl-tRNA synthetase 0.0028 0.0031 0.0033
Loa Loa (eye worm) DR-78 0.0034 0.0055 0.0077
Schistosoma mansoni polycystin 1-related 0.0059 0.0159 0.0239
Echinococcus granulosus mitogen activated protein kinase 3 0.0104 0.0342 0.0535
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0158 0.0562 0.4044
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0078 0.0237 0.1614
Brugia malayi hypothetical protein 0.0033 0.0052 0.0144
Brugia malayi Importin beta-1 subunit 0.0145 0.0509 0.1417
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0039 0.0079 0.0423
Loa Loa (eye worm) hypothetical protein 0.0334 0.1278 0.2045
Schistosoma mansoni hypothetical protein 0.0185 0.0672 0.1065
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.003 0.0039 0.0126
Onchocerca volvulus Pyruvate kinase homolog 0.0066 0.0188 0.127
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.0209 0.0322
Echinococcus multilocularis pyruvate kinase 0.0066 0.0188 0.018
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0325 0.0505
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0334 0.1278 0.2041
Leishmania major importin beta-1 subunit, putative 0.0118 0.0397 0.1144
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0104 0.0342 0.1019
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0896 0.1426
Echinococcus granulosus neutral alpha glucosidase AB 0.0074 0.0218 0.0336
Onchocerca volvulus Alhambra homolog 0.0058 0.0155 0.1006
Plasmodium falciparum pyruvate kinase 0.0066 0.0188 0.0833
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0079 0.045
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0079 0.045
Echinococcus multilocularis neutral alpha glucosidase AB 0.0074 0.0218 0.0209
Trichomonas vaginalis hypothetical protein 0.0027 0.003 0.0061
Brugia malayi Bromodomain containing protein 0.0062 0.017 0.0474
Loa Loa (eye worm) hypothetical protein 0.0334 0.1278 0.2045
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0039 0.0134
Echinococcus multilocularis GPCR, family 2 0.0111 0.0371 0.0362
Schistosoma mansoni hypothetical protein 0.0452 0.1757 0.2812
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0078 0.0237 0.0705
Trichomonas vaginalis antibiotic synthetase, putative 0.0078 0.0237 0.1075
Schistosoma mansoni hypothetical protein 0.1078 0.4306 0.6916
Trichomonas vaginalis maltase-glucoamylase, putative 0.0074 0.0218 0.0977
Mycobacterium tuberculosis Probable esterase LipL 0.0334 0.1278 0.1471
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.064 0.3044
Brugia malayi beta-lactamase 0.0334 0.1278 0.3561
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0352 0.1349 0.2159
Loa Loa (eye worm) hypothetical protein 0.0334 0.1278 0.2045
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0029 0.0054
Toxoplasma gondii HEAT repeat-containing protein 0.0145 0.0509 0.3647
Loa Loa (eye worm) hypothetical protein 0.0034 0.0055 0.0077
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0037 0.007 0.0061
Mycobacterium tuberculosis Probable reductase 0.0195 0.0714 0.0814
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0334 0.1278 0.3561
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0218 0.0977
Schistosoma mansoni nuclear receptor nhr-48 0.0034 0.0055 0.0072
Schistosoma mansoni importin beta-1 0.0145 0.0509 0.0802
Entamoeba histolytica HEAT repeat domain containing protein 0.0027 0.003 0.0044
Leishmania major alpha glucosidase II subunit, putative 0.0074 0.0218 0.0591
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0237 0.0662
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0217 0.0802 0.0917
Toxoplasma gondii exonuclease III APE 0.0077 0.0231 0.1568
Echinococcus multilocularis jumonji domain containing protein 0.0081 0.0248 0.0239
Echinococcus granulosus serine protein kinase ATM 0.0026 0.0022 0.0021
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0038 0.0072 0.0098
Echinococcus multilocularis RUN 0.0059 0.0159 0.0151
Plasmodium vivax transportin, putative 0.0027 0.003 0.0063
Schistosoma mansoni lipoxygenase 0.0166 0.0594 0.0938
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0039 0.0079 0.0114
Entamoeba histolytica protein kinase, putative 0.0039 0.0079 0.0325
Brugia malayi nuclear receptor NHR-88 0.0034 0.0055 0.0154
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0334 0.1278 0.2045
Trichomonas vaginalis esterase, putative 0.0334 0.1278 0.6161
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.0209 0.02
Brugia malayi nuclear receptor NHR-67 0.0034 0.0055 0.0154
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0079 0.0112
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0078 0.0237 0.026
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0037 0.007 0.0196
Trypanosoma brucei hypothetical protein, conserved 0.0334 0.1278 1
Loa Loa (eye worm) hypothetical protein 0.0334 0.1278 0.2045
Echinococcus multilocularis mitogen activated protein kinase 3 0.0104 0.0342 0.0333
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0149 0.0525 0.0516
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0237 0.0662
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0034 0.0055 0.0072
Loa Loa (eye worm) hypothetical protein 0.0034 0.0055 0.0077
Echinococcus multilocularis acetylcholinesterase 0.007 0.0204 0.0195
Plasmodium vivax lysine--tRNA ligase, putative 0.0028 0.0031 0.007
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.003 0.0043
Plasmodium vivax importin-beta 2, putative 0.0145 0.0509 0.2389
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0111 0.0371 0.1034
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0048 0.0062
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0097 0.0387
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0038
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.003 0.0039 0.0109
Echinococcus granulosus acetylcholinesterase 0.007 0.0204 0.0314
Mycobacterium tuberculosis Conserved protein 0.0334 0.1278 0.1471
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0044 0.0035
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.003 0.006
Schistosoma mansoni jumonji domain containing protein 0.0152 0.0535 0.0844
Mycobacterium tuberculosis Probable lipase LipD 0.0334 0.1278 0.1471
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0166 0.0594 0.0941
Loa Loa (eye worm) glycosyl hydrolase family 2 0.0503 0.1965 0.315
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0037 0.007 0.0096
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0048 0.0039
Giardia lamblia Kinase, CMGC MAPK 0.0104 0.0342 1
Plasmodium falciparum glutathione reductase 0.003 0.0039 0.0107
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0078 0.0237 0.0579
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.003 0.006
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0117 0.0394 0.0616
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.003 0.006
Brugia malayi photoreceptor-specific nuclear receptor 0.0071 0.0209 0.0582
Toxoplasma gondii NADPH-glutathione reductase 0.003 0.0039 0.0126
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0048 0.0202
Loa Loa (eye worm) doublecortin family protein 0.0059 0.0159 0.0244
Loa Loa (eye worm) sugar transporter 0.0125 0.0425 0.0672
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0331 0.1267 0.2027
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0044 0.0057
Plasmodium vivax thioredoxin reductase, putative 0.0086 0.0267 0.1214
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0079 0.0225
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.048 0.1438
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0079 0.045
Toxoplasma gondii lysine-tRNA ligase 0.0028 0.0031 0.0069
Echinococcus multilocularis lysyl tRNA synthetase 0.0028 0.0031 0.0022
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0048 0.0059
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0055 0.0075
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0097 0.0387
Mycobacterium ulcerans hypothetical protein 0.0154 0.0544 0.144
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0078 0.0237 0.026
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0111 0.0371 0.0362
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0166 0.0594 0.0585
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0048 0.0064
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0039 0.0105
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.01 0.0325 0.0316
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0077 0.0231 0.1206
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0048 0.0191
Loa Loa (eye worm) hypothetical protein 0.01 0.0325 0.051
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0074 0.0218 0.0338
Leishmania major 4-coumarate:coa ligase-like protein 0.0078 0.0237 0.0652
Echinococcus multilocularis lysosomal alpha glucosidase 0.0331 0.1267 0.1259
Brugia malayi ecdysteroid receptor 0.0071 0.0209 0.0582
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0117 0.0394 0.1018
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0044 0.0054
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0158 0.0562 0.149
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0071 0.0209 0.0582
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0027 0.003 0.0061
Echinococcus multilocularis pyruvate kinase 0.0034 0.0057 0.0048
Loa Loa (eye worm) jmjC domain-containing protein 0.0075 0.0225 0.035
Loa Loa (eye worm) hypothetical protein 0.0039 0.0079 0.0114
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.003 0.0039 0.0021
Loa Loa (eye worm) CXXC zinc finger family protein 0.0085 0.0266 0.0416
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.1106 0.3327
Trichomonas vaginalis penicillin-binding protein, putative 0.0334 0.1278 0.6161
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0237 0.0662
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0078 0.0237 0.0685
Mycobacterium tuberculosis Conserved hypothetical protein 0.0154 0.0544 0.0616
Entamoeba histolytica beta-galactosidase, putative 0.0356 0.1368 0.776
Loa Loa (eye worm) hypothetical protein 0.024 0.0896 0.143
Echinococcus granulosus serine:threonine protein kinase PLK1 0.01 0.0325 0.0508
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0158 0.0562 0.0553
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0078 0.0237 0.1071
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0029 0.0054
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.003 0.0039 0.0029
Trichomonas vaginalis beta-mannosidase, putative 0.0171 0.0614 0.2916
Toxoplasma gondii HEAT repeat-containing protein 0.0027 0.003 0.0058
Brugia malayi AMP-binding enzyme family protein 0.0902 0.359 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0039 0.0076 0.0424
Loa Loa (eye worm) hypothetical protein 0.0334 0.1278 0.2045
Trypanosoma brucei glucose transporter, putative 0.0039 0.0076 0.0424
Echinococcus granulosus lysyl tRNA synthetase 0.0028 0.0031 0.0036
Brugia malayi glutaminase DH11.1 0.0266 0.1001 0.2789
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0079 0.0109
Plasmodium vivax SET domain protein, putative 0.0031 0.0044 0.0134
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0048 0.0039
Loa Loa (eye worm) hypothetical protein 0.0034 0.0055 0.0077
Trypanosoma brucei glucose transporter 1E 0.0039 0.0076 0.0424
Onchocerca volvulus 0.0085 0.0266 0.1892
Onchocerca volvulus 0.0071 0.0209 0.1435
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0044 0.0096 0.055
Echinococcus multilocularis Polycystic kidney disease protein 0.0059 0.0159 0.0151
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0038 0.0072 0.0103
Mycobacterium ulcerans esterase/lipase LipP 0.0334 0.1278 0.3504
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0237 0.0662
Loa Loa (eye worm) hypothetical protein 0.0034 0.0055 0.0077
Plasmodium falciparum importin beta, putative 0.0145 0.0509 0.2389
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0082 0.0343
Schistosoma mansoni retinoic acid receptor RXR 0.0071 0.0209 0.0319
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0044 0.0096 0.0215
Leishmania major 4-coumarate:coa ligase-like protein 0.0078 0.0237 0.0652
Loa Loa (eye worm) thioredoxin reductase 0.0086 0.0267 0.0417
Leishmania major acetyl-CoA synthetase, putative 0.0078 0.0237 0.0652
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0237 0.026
Brugia malayi MAP kinase sur-1 0.0104 0.0342 0.0952
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0038 0.0072 0.0101
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0155 0.0672
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0024 0.0015 0.0006
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0115 0.0388 0.274
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.024 0.0896 0.1429
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.003 0.0039 0.0107
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0104 0.034 0.0379
Brugia malayi hypothetical protein 0.0038 0.0072 0.02
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0104 0.034 0.0379
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0902 0.359 1
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0039 0.0079 0.0219
Loa Loa (eye worm) glutaminase 0.0266 0.1001 0.1599
Loa Loa (eye worm) hypothetical protein 0.0145 0.0509 0.0806
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0048 0.0191
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0078 0.0237 0.0579
Plasmodium falciparum protein kinase 6 0.053 0.2075 1
Brugia malayi Sodium:solute symporter family protein 0.0115 0.0388 0.108
Loa Loa (eye worm) oxidoreductase 0.0078 0.0237 0.037
Plasmodium vivax calcium-dependent protein kinase, putative 0.0039 0.0079 0.03
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0071 0.0209 0.0582
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0195 0.0714 0.2147
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0079 0.0109
Onchocerca volvulus 0.0078 0.0237 0.1664
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0115 0.0388 0.0379
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0071 0.0209 0.0322
Entamoeba histolytica hypothetical protein 0.0452 0.1757 1
Mycobacterium ulcerans acetyl-CoA synthetase 0.0078 0.0237 0.0579
Schistosoma mansoni jumonji/arid domain-containing protein 0.0075 0.0225 0.0345
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0072 0.02
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0039 0.0079 0.03
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.003 0.0039 0.0134
Mycobacterium tuberculosis Probable dehydrogenase 0.0195 0.0714 0.0814
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0055 0.0046
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0079 0.0114
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0237 0.0579
Mycobacterium ulcerans flavoprotein disulfide reductase 0.003 0.0039 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0527 0.2064 1
Plasmodium falciparum proline--tRNA ligase 0.0044 0.0096 0.0382
Echinococcus granulosus pyruvate kinase 0.0034 0.0057 0.0077
Loa Loa (eye worm) jmjC domain-containing protein 0.012 0.0408 0.0644
Trichomonas vaginalis mercuric reductase, putative 0.003 0.0039 0.0105
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0078 0.0237 0.0705
Mycobacterium ulcerans hypothetical protein 0.0334 0.1278 0.3504
Trypanosoma brucei unspecified product 0.0027 0.0029 0.0054
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0037 0.007 0.0258
Echinococcus granulosus beta LACTamase domain containing family member 0.0334 0.1278 0.2043
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0085 0.0245
Trypanosoma brucei glucose transporter, putative 0.0039 0.0076 0.0424
Brugia malayi Beta-glucuronidase precursor 0.0489 0.1907 0.5312
Schistosoma mansoni protein kinase 0.0039 0.0079 0.0109
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0237 0.0579
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0078 0.0237 0.0652
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0079 0.045
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0188 0.0291
Leishmania major pyruvate kinase 0.0066 0.0188 0.0501
Plasmodium falciparum calcium-dependent protein kinase 3 0.0039 0.0079 0.03
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0334 0.1278 0.1471
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0039 0.0079 0.0114
Loa Loa (eye worm) pyruvate kinase 0.0066 0.0188 0.0291
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0117 0.0394 0.0619
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0077 0.0231 0.3681
Schistosoma mansoni pyruvate kinase 0.0066 0.0188 0.0286
Onchocerca volvulus 0.0034 0.0055 0.0205
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0237 0.0579

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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