Detailed information for compound 800285

Basic information

Technical information
  • TDR Targets ID: 800285
  • Name: 2-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5 -a]pyrimidine
  • MW: 331.216 | Formula: C14H7F6N3
  • H donors: 0 H acceptors: 2 LogP: 3.83 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: FC(c1cc(nc2n1nc(c2)c1ccccc1)C(F)(F)F)(F)F
  • InChi: 1S/C14H7F6N3/c15-13(16,17)10-7-11(14(18,19)20)23-12(21-10)6-9(22-23)8-4-2-1-3-5-8/h1-7H
  • InChiKey: HWUAAKUUJSUKTE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • Bionet2_001250
  • Imidazo[1,5-a]pyrimidine, 5,7-bis(triffluoromethyl)-2-phenyl-
  • ZINC00128308
  • A2349/0099236

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni calpain-7 (C02 family) 0.0019 0.0079 0.0088
Schistosoma mansoni ap endonuclease 0.0018 0.0072 0.008
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.1414 0.4512
Brugia malayi Flap endonuclease-1 0.0056 0.0498 0.0688
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0027 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0205 0.0424
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0897 0.0997
Echinococcus granulosus smad 0.0018 0.0065 0.0072
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0465 0.0517
Brugia malayi polk-prov protein 0.0057 0.0508 0.0702
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0014 0.0045
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0292 0.3134 1
Schistosoma mansoni zinc finger protein 0.0015 0.0037 0.0041
Onchocerca volvulus 0.0014 0.0027 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0205 0.0284
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0189 0.1974 0.2195
Echinococcus multilocularis dna polymerase eta 0.0113 0.1125 0.1251
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0205 0.0228
Leishmania major DNA polymerase kappa, putative 0.0025 0.0153 0.0376
Trichomonas vaginalis glutaminase, putative 0.0265 0.2824 0.9175
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0433 0.0482
Brugia malayi nuclear hormone receptor 0.003 0.0205 0.0284
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0189 0.0716
Brugia malayi latrophilin 2 splice variant baaae 0.0109 0.1089 0.1506
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0027 0.0057
Echinococcus granulosus cpg binding protein 0.0095 0.0929 0.1033
Trichomonas vaginalis DNA helicase recq1, putative 0.0054 0.0473 0.1538
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0248 0.2636 0.8411
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0205 0.0228
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0079 0.0253
Schistosoma mansoni inositol monophosphatase 0.0036 0.0274 0.0305
Echinococcus multilocularis chromobox protein 1 0.0069 0.0634 0.0705
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0328 0.1046
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0079 0.0137
Loa Loa (eye worm) hypothetical protein 0.0165 0.1707 0.3526
Trypanosoma brucei antigen, putative 0.0019 0.0079 0.0253
Loa Loa (eye worm) RecQ helicase 0.0054 0.0473 0.0978
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0056 0.0493 0.187
Schistosoma mansoni Smad4 0.0018 0.0065 0.0072
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0121 0.0395
Trypanosoma brucei DNA polymerase IV, putative 0.0106 0.1052 0.3356
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0027 0.003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0027 0.003
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0205 0.0424
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0184 0.0205
Brugia malayi Bromodomain containing protein 0.0033 0.0234 0.0324
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0205 0.0228
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0057
Echinococcus granulosus Smad4 0.0018 0.0065 0.0072
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0121 0.0395
Brugia malayi Muscleblind-like protein 0.0445 0.4841 0.6693
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0392 0.0436
Echinococcus multilocularis dna polymerase kappa 0.0114 0.114 0.1267
Loa Loa (eye worm) BRM protein 0.0042 0.0332 0.0687
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0014 0.0027 0.0102
Plasmodium falciparum DNA repair protein REV1, putative 0.0025 0.0153 0.0581
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0041 0.0332 0.0369
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0433 0.1644
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0072 0.0233
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0067 0.0612 0.0681
Brugia malayi Disco-interacting protein 2 homolog 0.0037 0.0285 0.0394
Brugia malayi isocitrate dehydrogenase 0.0032 0.0221 0.0306
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0205 0.0228
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0159 0.0177
Brugia malayi nuclear receptor NHR-88 0.003 0.0205 0.0284
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.0917 0.102
Brugia malayi tailless protein 0.0014 0.0027 0.0038
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0465 0.0517
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0079 0.0253
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0055 0.0061
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0056 0.0498 0.1488
Trypanosoma cruzi kinesin, putative 0.0019 0.0079 0.0253
Schistosoma mansoni hypothetical protein 0.0339 0.3649 0.4057
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0139 0.0452
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0205 0.0228
Trypanosoma brucei chrX additional, unordered contigs 0.0025 0.0153 0.0489
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0115 0.1155 0.3686
Echinococcus granulosus dual specificity mitogen activated protein 0.0073 0.0689 0.0766
Brugia malayi Associated with TFs and helicases family protein 0.0022 0.012 0.0165
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0205 0.0228
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0073 0.0689 0.0953
Leishmania major DNA polymerase eta, putative 0.0113 0.1125 0.3513
Chlamydia trachomatis DNA ligase 0.0012 0 0.5
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0022 0.0118 0.0132
Loa Loa (eye worm) hypothetical protein 0.0016 0.0046 0.0096
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0897 0.1852
Toxoplasma gondii hypothetical protein 0.0082 0.0784 0.2973
Plasmodium falciparum flap endonuclease 1 0.0056 0.0498 0.1888
Onchocerca volvulus 0.0045 0.0366 0.0366
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0079 0.0253
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0433 0.1383
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0274 0.1041
Loa Loa (eye worm) DR-78 0.0014 0.0027 0.0057
Onchocerca volvulus 0.0043 0.035 0.035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3078 1
Schistosoma mansoni nuclear receptor 0.0014 0.0027 0.003
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0065 0.0072
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0022 0.0118 0.0132
Echinococcus granulosus importin subunit beta 1 0.0028 0.018 0.0201
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0433 0.1408
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.3078 0.3725
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0225 0.025
Onchocerca volvulus 0.003 0.0205 0.0205
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0072 0.0087
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0897 0.0997
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0056 0.0062
Brugia malayi CHD4 protein 0.0016 0.0051 0.0071
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0897 0.124
Entamoeba histolytica hypothetical protein 0.0078 0.0737 0.0892
Onchocerca volvulus 0.0047 0.0392 0.0392
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0139 0.0452
Trypanosoma cruzi DNA damage repair protein, putative 0.0025 0.0153 0.0489
Brugia malayi Bloom's syndrome protein homolog 0.0054 0.0473 0.0655
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0263 0.0293
Trypanosoma brucei DNA polymerase kappa, putative 0.0114 0.114 0.3637
Trypanosoma brucei DNA damage repair protein, putative 0.0025 0.0153 0.0489
Echinococcus multilocularis calpain family protein 1, d 0.0045 0.0366 0.0407
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0082 0.0784 0.2973
Loa Loa (eye worm) hypothetical protein 0.0047 0.0393 0.0811
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0221 0.0839
Loa Loa (eye worm) hypothetical protein 0.007 0.0645 0.1333
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.053 0.1094
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0433 0.128
Echinococcus granulosus zinc finger protein 0.0024 0.0139 0.0155
Schistosoma mansoni calpain-7 (C02 family) 0.0019 0.0079 0.0088
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0027 0.003
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0274 0.0875
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0057
Loa Loa (eye worm) calpain 0.0019 0.0079 0.0164
Brugia malayi nuclear receptor RXR 0.0016 0.0046 0.0064
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0274 0.0305
Loa Loa (eye worm) inositol-1 0.0036 0.0274 0.0567
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0412 0.0459
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0019 0.0082 0.0091
Echinococcus granulosus calpain 0.0019 0.0079 0.0088
Schistosoma mansoni SET domain protein 0.0041 0.0332 0.0369
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0065 0.0072
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0221 0.0246
Loa Loa (eye worm) calpain 5 0.0019 0.0079 0.0164
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.1366 0.4291
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0134 0.1366 0.4357
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0073 0.0689 0.2106
Echinococcus granulosus calpain 7 C02 family 0.0019 0.0079 0.0088
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0065 0.0072
Trypanosoma cruzi DNA polymerase kappa, putative 0.0114 0.114 0.3637
Brugia malayi ecdysone receptor 0.0014 0.0027 0.0038
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0221 0.0457
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0392 0.0436
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0046 0.0052
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0221 0.0246
Schistosoma mansoni DNA helicase recq5 0.0022 0.0118 0.0132
Loa Loa (eye worm) hypothetical protein 0.003 0.0205 0.0424
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0433 0.0482
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.018 0.0685
Brugia malayi jmjC domain containing protein 0.0094 0.0917 0.1268
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0139 0.0452
Leishmania major DNA polymerase kappa, putative 0.009 0.0873 0.27
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0057
Brugia malayi nuclear receptor NHR-67 0.0014 0.0027 0.0038
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.3134 1
Brugia malayi Smad1 0.0018 0.0065 0.009
Brugia malayi calpain 7 0.0019 0.0079 0.0109
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.1436 1
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0065 0.0072
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0027 0.003
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.0019 0.0082 0.0312
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0205 0.0205
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0465 0.0517
Trypanosoma brucei telomerase reverse transcriptase 0.0248 0.2636 0.8411
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3078 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0114 0.114 0.3637
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0274 0.0332
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0027 0.003
Mycobacterium ulcerans DNA polymerase IV 0.0114 0.114 0.4036
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3078 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0153 0.017
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0134 0.1366 0.4357
Trichomonas vaginalis DNA polymerase eta, putative 0.0114 0.114 0.3703
Schistosoma mansoni helicase 0.0067 0.0621 0.069
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0065 0.0135
Loa Loa (eye worm) BRM protein 0.0036 0.027 0.0558
Schistosoma mansoni inositol monophosphatase 0.0036 0.0274 0.0305
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0205 0.0228
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0051 0.0434 0.0482
Loa Loa (eye worm) RNA binding protein 0.0138 0.1409 0.2911
Brugia malayi calpain family protein 1 0.0063 0.0576 0.0796
Loa Loa (eye worm) latrophilin receptor protein 2 0.0051 0.0434 0.0896
Schistosoma mansoni hypothetical protein 0.0051 0.0434 0.0482
Brugia malayi SET domain containing protein 0.0013 0.0015 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0508 0.162
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0153 0.017
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0205 0.0284
Loa Loa (eye worm) hypothetical protein 0.0049 0.0418 0.0862
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0248 0.2636 0.8411
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0205 0.0228
Brugia malayi PHD-finger family protein 0.0015 0.0031 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0014 0.0045
Echinococcus granulosus jumonji domain containing protein 0.004 0.0314 0.0349
Trypanosoma cruzi DNA damage repair protein, putative 0.0025 0.0153 0.0489
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0072 0.0273
Loa Loa (eye worm) hypothetical protein 0.0051 0.0434 0.0896
Entamoeba histolytica Flap nuclease, putative 0.0056 0.0498 0.0602
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0221 0.0706
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0225 0.025
Loa Loa (eye worm) hypothetical protein 0.0057 0.0508 0.1049
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0392 0.0436
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0897 0.0997
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0015 0.0036 0.004
Echinococcus multilocularis dual specificity mitogen activated protein 0.0073 0.0689 0.0766
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0078 0.0737 0.082
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0205 0.0284
Echinococcus multilocularis peregrin 0.0044 0.0361 0.0401
Trypanosoma brucei unspecified product 0.0057 0.0501 0.1598
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0205 0.0424
Schistosoma mansoni zinc finger protein 0.0024 0.0139 0.0155
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0221 0.0839
Brugia malayi Inositol-1 0.0036 0.0274 0.0379
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0205 0.0205
Plasmodium falciparum phd finger protein, putative 0.0029 0.0189 0.0716
Plasmodium vivax importin-beta 2, putative 0.0028 0.018 0.0685
Brugia malayi nuclear receptor NHR-88 0.0014 0.0027 0.0038
Brugia malayi ImpB/MucB/SamB family protein 0.0082 0.0785 0.1085
Loa Loa (eye worm) hypothetical protein 0.0016 0.0046 0.0096
Trypanosoma brucei ISWI complex protein 0.0015 0.0037 0.0117
Schistosoma mansoni hypothetical protein 0.0015 0.0037 0.0041
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0121 0.0395
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0033 0.0241 0.0915
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0205 0.0228
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0205 0.0228
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0589 0.1878
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0205 0.0284
Brugia malayi ImpB/MucB/SamB family protein 0.0113 0.1125 0.1555
Leishmania major hypothetical protein, conserved 0.003 0.0205 0.0543
Loa Loa (eye worm) pigment dispersing factor receptor c 0.016 0.1654 0.3416
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0508 0.162
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0634 0.2059
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0072 0.008
Trypanosoma brucei unspecified product 0.0057 0.0501 0.1598
Brugia malayi mbt repeat family protein 0.0047 0.0392 0.0543
Giardia lamblia Sgs1 DNA helicase, putative 0.0022 0.0118 0.0143
Loa Loa (eye worm) hypothetical protein 0.0063 0.0576 0.119
Trypanosoma brucei calpain-like protein, putative 0.0134 0.1366 0.4357
Loa Loa (eye worm) hypothetical protein 0.0016 0.0046 0.0096
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0205 0.0205
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0314 0.0349
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0027 0.0038
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.009 0.0873 0.27
Brugia malayi tumor suppressor. 0.0331 0.3566 0.493
Entamoeba histolytica hypothetical protein 0.0078 0.0737 0.0892
Loa Loa (eye worm) hypothetical protein 0.003 0.0205 0.0424
Schistosoma mansoni protein kinase 0.0073 0.0689 0.0766
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0205 0.0777
Schistosoma mansoni thyroid hormone receptor 0.003 0.0205 0.0228
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0134 0.1366 0.4357
Entamoeba histolytica deoxycytidyl transferase, putative 0.0082 0.0785 0.095
Loa Loa (eye worm) hypothetical protein 0.0028 0.018 0.0373
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0079 0.0253
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0057
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0027 0.003
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0274 0.0891
Brugia malayi MH2 domain containing protein 0.0018 0.0065 0.009
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0274 0.0891
Leishmania major kinesin, putative 0.0019 0.0079 0.0137
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0082 0.0785 0.0873
Schistosoma mansoni transcription factor LCR-F1 0.0078 0.0737 0.082
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0139 0.0452
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0079 0.0253
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0392 0.0436
Schistosoma mansoni thyroid hormone receptor 0.003 0.0205 0.0228
Loa Loa (eye worm) tumor suppressor 0.0331 0.3566 0.7365
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0205 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0014 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0298 0.0967
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0298 0.0967
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0221 0.0596
Brugia malayi glutaminase DH11.1 0.0265 0.2824 0.3905
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0897 0.0997
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0634 0.1309
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0139 0.0452
Entamoeba histolytica hypothetical protein 0.0078 0.0737 0.0892
Trypanosoma cruzi DNA polymerase kappa, putative 0.0114 0.114 0.3637
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0274 0.0971
Schistosoma mansoni hypothetical protein 0.0029 0.0189 0.021
Trypanosoma brucei DNA polymerase kappa, putative 0.0114 0.114 0.3637
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0046 0.0096
Entamoeba histolytica protein kinase, putative 0.002 0.0089 0.0108
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0263 0.0293
Echinococcus granulosus chromobox protein 1 0.0069 0.0634 0.0705
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0121 0.0388
Schistosoma mansoni importin beta-1 0.0028 0.018 0.0201
Trypanosoma cruzi ISWI complex protein 0.0015 0.0037 0.0117
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0115 0.1155 0.3686
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0205 0.0424
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0056 0.0498 0.1888
Trypanosoma brucei DNA polymerase kappa, putative 0.0114 0.114 0.3637
Brugia malayi calpain family protein 1 0.0063 0.0576 0.0796
Loa Loa (eye worm) hypothetical protein 0.003 0.0205 0.0424
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0072 0.008
Trypanosoma brucei DNA polymerase eta, putative 0.0113 0.1125 0.3589
Plasmodium vivax calpain, putative 0.0019 0.0079 0.03
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0056 0.0498 0.1588
Echinococcus granulosus Chromo domain 0.0022 0.012 0.0133
Trichomonas vaginalis STE family protein kinase 0.0073 0.0689 0.2238
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0022 0.0118 0.0132
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0205 0.0228
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0043 0.035 0.039
Brugia malayi ecdysteroid receptor 0.003 0.0205 0.0284
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.0019 0.0082 0.01
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0702 0.078
Echinococcus multilocularis hypothetical protein 0.0019 0.0079 0.0088
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0049 0.0412 0.0459
Brugia malayi hypothetical protein 0.0014 0.0027 0.0038
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0115 0.1155 0.3686
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0433 0.0482
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3078 1
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0027 0.0038
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.0051 0.0057
Brugia malayi mbt repeat family protein 0.0047 0.0392 0.0543
Echinococcus granulosus tar DNA binding protein 0.0138 0.1409 0.1567
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.0019 0.0082 0.0312
Schistosoma mansoni hypothetical protein 0.0028 0.0181 0.0202
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0205 0.0777
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0079 0.0253
Echinococcus multilocularis bloom syndrome protein 0.0054 0.0473 0.0526
Trichomonas vaginalis helicase, putative 0.0013 0.0014 0.0045
Schistosoma mansoni DNA polymerase eta 0.0113 0.1125 0.1251
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0433 0.0482
Loa Loa (eye worm) hypothetical protein 0.003 0.0205 0.0424
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0205 0.0228
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0205 0.0284
Echinococcus multilocularis protein quaking 0.0028 0.0181 0.0202
Brugia malayi nuclear receptor RXR 0.0014 0.0027 0.0038
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0205 0.0777
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0172 0.056
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0134 0.1366 0.4357
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0221 0.0306
Entamoeba histolytica recQ family helicase, putative 0.0029 0.0192 0.0232
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0232 0.1053
Loa Loa (eye worm) hypothetical protein 0.0022 0.0118 0.0244
Schistosoma mansoni tar DNA-binding protein 0.0138 0.1409 0.1567
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0041 0.0332 0.0369
Echinococcus multilocularis calpain A 0.0067 0.0612 0.0681
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0057
Echinococcus granulosus histone lysine methyltransferase setb 0.0049 0.0412 0.0459
Brugia malayi BRM protein 0.0067 0.0621 0.0858
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0051 0.0434 0.0482
Echinococcus granulosus bloom syndrome protein 0.0054 0.0473 0.0526
Loa Loa (eye worm) MH2 domain-containing protein 0.0258 0.2752 0.5684
Schistosoma mansoni hypothetical protein 0.0051 0.0434 0.0482
Treponema pallidum fructose-bisphosphate aldolase 0.0287 0.3078 1
Onchocerca volvulus 0.0236 0.2498 0.2498
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0014 0.0045
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0465 0.0643
Schistosoma mansoni hypothetical protein 0.0016 0.0052 0.0058
Schistosoma mansoni SET domain protein 0.002 0.0094 0.0104
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3078 1
Echinococcus multilocularis dnaJ subfamily B 0.0817 0.8993 1
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0073 0.0689 0.2198
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0205 0.0228
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0022 0.0118 0.0449
Brugia malayi hypothetical protein 0.0016 0.0046 0.0064
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0205 0.0228
Schistosoma mansoni cpg binding protein 0.0095 0.0929 0.1033
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0046 0.0052
Schistosoma mansoni hypothetical protein 0.0014 0.0019 0.0022
Echinococcus multilocularis muscleblind protein 0.0445 0.4841 0.5383
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0392 0.0436
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0225 0.0854
Brugia malayi Pre-SET motif family protein 0.0207 0.2183 0.3018
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0073 0.0689 0.2198
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0134 0.1366 0.4291
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0072 0.0234
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0205 0.0284
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0274 0.0891
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0057
Brugia malayi steroid hormone receptor 0.003 0.0205 0.0284
Toxoplasma gondii hypothetical protein 0.0047 0.0395 0.15
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0205 0.0284
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0205 0.0777
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0232 0.1614
Loa Loa (eye worm) hypothetical protein 0.016 0.1654 0.3416
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0027 0.0057
Schistosoma mansoni hypothetical protein 0.0051 0.0434 0.0482
Schistosoma mansoni coup transcription factor 0.003 0.0205 0.0228
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0118 0.0164
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0072 0.0255
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0072 0.023
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0073 0.0689 0.1423
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0078 0.0737 0.082
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.018 0.0576
Echinococcus granulosus global transcription activator snf2l2 0.0067 0.0621 0.069
Plasmodium falciparum importin beta, putative 0.0028 0.018 0.0685
Schistosoma mansoni tar DNA-binding protein 0.0138 0.1409 0.1567
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0027 0.0027
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0221 0.0246
Schistosoma mansoni microtubule-associated protein tau 0.0679 0.7446 0.828
Schistosoma mansoni blooms syndrome DNA helicase 0.0043 0.0346 0.0385
Echinococcus multilocularis calpain 7 (C02 family) 0.0019 0.0079 0.0088
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0392 0.0436
Brugia malayi Temporarily assigned gene name protein 44 0.0028 0.0182 0.0251
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0433 0.0895
Brugia malayi CXXC zinc finger family protein 0.009 0.0872 0.1205
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0065 0.0135
Echinococcus multilocularis Chromo domain 0.0022 0.012 0.0133
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0118 0.0164
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0189 0.0716
Brugia malayi Bromodomain containing protein 0.0039 0.0308 0.0426
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0014 0.003 0.0033
Brugia malayi hypothetical protein 0.0078 0.0737 0.102
Leishmania major telomerase reverse transcriptase, putative 0.0248 0.2636 0.8392
Toxoplasma gondii RNA-directed DNA polymerase 0.0248 0.2636 1
Schistosoma mansoni smad1 5 8 and 0.0018 0.0065 0.0072
Trypanosoma brucei DNA polymerase kappa, putative 0.0114 0.114 0.3637
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0072 0.0234
Schistosoma mansoni DNA helicase recq1 0.0022 0.0118 0.0132
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0124 0.1254 0.1395
Loa Loa (eye worm) Smad1 0.0018 0.0065 0.0135
Schistosoma mansoni nuclear hormone receptor 0.003 0.0205 0.0228
Trypanosoma brucei protein kinase, putative 0.0051 0.0433 0.1383
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0057
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0094 0.0104
Echinococcus granulosus dna polymerase eta 0.0113 0.1125 0.1251
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0221 0.0706
Loa Loa (eye worm) hypothetical protein 0.0029 0.0189 0.039
Trypanosoma cruzi DNA polymerase kappa, putative 0.0114 0.114 0.3637
Schistosoma mansoni ap endonuclease 0.0018 0.0072 0.008
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0072 0.0273
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0153 0.0489
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0072 0.01
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0205 0.0228
Trypanosoma brucei DNA polymerase kappa, putative 0.009 0.0873 0.2786
Schistosoma mansoni smad 0.0018 0.0065 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0014 0.0045
Trichomonas vaginalis set domain proteins, putative 0.0236 0.2498 0.8117
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0079 0.0253
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0056 0.0062
Schistosoma mansoni zinc finger protein 0.0014 0.0027 0.003
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0014 0.003 0.0033
Loa Loa (eye worm) hypothetical protein 0.003 0.0205 0.0424
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0205 0.0228
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0634 0.2059
Giardia lamblia PHD finger protein 15 0.0029 0.0189 0.0229
Toxoplasma gondii exonuclease III APE 0.0018 0.0072 0.0273
Echinococcus multilocularis geminin 0.0339 0.3649 0.4057
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.016 0.1654 0.2287
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0014 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0072 0.0233
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.3134 1
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0019 0.0082 0.0091
Schistosoma mansoni flap endonuclease-1 0.0051 0.0437 0.0486
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0433 0.1383
Echinococcus multilocularis cpg binding protein 0.0095 0.0929 0.1033
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0022 0.0118 0.0244
Schistosoma mansoni Mername-AA248 (C02 family) 0.0019 0.0079 0.0088
Brugia malayi PHD-finger family protein 0.0029 0.0198 0.0274
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0256 0.0285
Loa Loa (eye worm) hypothetical protein 0.003 0.0205 0.0423
Leishmania major DNA polymerase eta, putative 0.0056 0.0493 0.1473
Schistosoma mansoni hypothetical protein 0.0289 0.3094 0.344
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0153 0.0489
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0046 0.0064
Onchocerca volvulus 0.0014 0.0027 0.0027
Loa Loa (eye worm) transcription factor SMAD2 0.0258 0.2752 0.5684
Trichomonas vaginalis lymphoid specific helicase, putative 0.0014 0.0027 0.0088
Loa Loa (eye worm) hypothetical protein 0.0038 0.029 0.0599
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0079 0.0253
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.0015 0.0036 0.004
Onchocerca volvulus 0.003 0.0205 0.0205
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0072 0.0087
Plasmodium vivax DNA repair protein REV1, putative 0.0025 0.0153 0.0581
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0221 0.0839
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0205 0.0654
Giardia lamblia Kinase, STE STE20 0.0073 0.0689 0.0834
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0392 0.0392
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0022 0.0118 0.0132
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0067 0.0612 0.0681
Schistosoma mansoni smad1 5 8 and 0.0018 0.0065 0.0072
Loa Loa (eye worm) hypothetical protein 0.0109 0.1089 0.225
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0014 0.0045
Brugia malayi hypothetical protein 0.0014 0.0027 0.0038
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0221 0.0246
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0205 0.0284
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.1414 0.4447
Schistosoma mansoni chromobox protein 0.0069 0.0634 0.0705
Loa Loa (eye worm) hypothetical protein 0.0038 0.0298 0.0615
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0897 0.0997
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0065 0.0072
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0114 0.114 0.3703
Leishmania major DNA damage repair protein, putative 0.0025 0.0153 0.0376
Echinococcus granulosus microtubule associated protein 2 0.0679 0.7446 0.828
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0014 0.0045
Echinococcus multilocularis global transcription activator snf2l2 0.0067 0.0621 0.069
Giardia lamblia DNA repair protein RAD52 0.0752 0.8264 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0205 0.0284
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0205 0.0284
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0082 0.0169
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0221 0.0246
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3078 1
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0056 0.0062
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0205 0.0228
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0079 0.0253
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0221 0.0983
Plasmodium falciparum telomerase reverse transcriptase 0.0248 0.2636 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0114 0.114 0.3637
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0392 0.0811
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0328 0.1046
Schistosoma mansoni hypothetical protein 0.0022 0.012 0.0133
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0221 0.0246
Schistosoma mansoni phd finger protein 0.0015 0.0041 0.0045
Toxoplasma gondii DNA methyltransferase 2, putative 0.0019 0.0082 0.0312
Onchocerca volvulus 0.0037 0.0285 0.0285
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0328 0.1046
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0205 0.0228
Plasmodium vivax telomerase reverse transcriptase, putative 0.0248 0.2636 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0134 0.1366 0.4357
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0433 0.1383
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0205 0.0284
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0189 0.1974 0.2195
Echinococcus granulosus snurportin 1 0.0298 0.3197 0.3555
Trypanosoma brucei calpain, putative 0.0115 0.1155 0.3686
Echinococcus multilocularis GPCR, family 2 0.0051 0.0434 0.0482
Echinococcus multilocularis calpain 0.0019 0.0079 0.0088
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0153 0.0489
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0082 0.0785 0.0873
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0298 0.3197 0.6603
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0118 0.0449
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0328 0.1046
Echinococcus granulosus peregrin 0.0044 0.0361 0.0401
Trichomonas vaginalis DNA helicase recq, putative 0.0029 0.0192 0.0623
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0205 0.0424
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0051 0.0434 0.0482
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0025 0.0153 0.0581
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.0019 0.0022
Brugia malayi chromobox protein homolog 3 0.0038 0.0298 0.0411
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0139 0.0452
Loa Loa (eye worm) hypothetical protein 0.003 0.0205 0.0424
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0036 0.0273 0.1035
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0051 0.0057
Leishmania major modification methylase-like protein 0.0019 0.0082 0.0147
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.058 0.0645
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0205 0.0654
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0205 0.0424
Brugia malayi MH1 domain containing protein 0.0018 0.0065 0.009
Loa Loa (eye worm) hypothetical protein 0.003 0.0205 0.0424
Schistosoma mansoni tar DNA-binding protein 0.0138 0.1409 0.1567
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0752 0.8264 1
Trichomonas vaginalis flap endonuclease-1, putative 0.0056 0.0498 0.1616
Echinococcus granulosus protein quaking 0.0028 0.0181 0.0202
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0061 0.0199
Echinococcus multilocularis Smad4 0.0018 0.0065 0.0072
Brugia malayi SET domain containing protein 0.0015 0.0035 0.0048
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0027 0.0038
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0189 0.039
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0079 0.0253
Loa Loa (eye worm) hypothetical protein 0.0113 0.1125 0.2323
Loa Loa (eye worm) hypothetical protein 0.0445 0.4841 1
Echinococcus granulosus FTZ F1 alpha 0.003 0.0205 0.0228
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0205 0.0284
Schistosoma mansoni cpg binding protein 0.009 0.0872 0.0969
Brugia malayi PHD-finger family protein 0.0029 0.0189 0.0261
Schistosoma mansoni DNA polymerase IV / kappa 0.0025 0.0153 0.017
Schistosoma mansoni hypothetical protein 0.0109 0.1089 0.1211
Giardia lamblia Telomerase catalytic subunit 0.0248 0.2636 0.319
Entamoeba histolytica hypothetical protein 0.0214 0.2257 0.2732
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0428 0.1367
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0205 0.0424
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0012 0.0047
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0897 0.0997
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0029 0.0192 0.0501
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0274 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0205 0.0424
Giardia lamblia DINP protein human, muc B family 0.009 0.0873 0.1057
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0314 0.0349
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0027 0.0038
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0221 0.0706
Echinococcus granulosus calpain A 0.0019 0.0079 0.0088
Loa Loa (eye worm) hypothetical protein 0.0042 0.0335 0.0692
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0027 0.003
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.1436 0.8997
Loa Loa (eye worm) hypothetical protein 0.0045 0.0366 0.0755
Loa Loa (eye worm) hypothetical protein 0.0445 0.4841 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0465 0.096
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0014 0.0045
Echinococcus multilocularis tar DNA binding protein 0.0138 0.1409 0.1567
Echinococcus multilocularis snurportin 1 0.0298 0.3197 0.3555
Mycobacterium tuberculosis Conserved hypothetical protein 0.0154 0.1589 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0051 0.0434 0.0599
Trypanosoma brucei DNA polymerase kappa, putative 0.0114 0.114 0.3637
Trichomonas vaginalis STE family protein kinase 0.0073 0.0689 0.2238
Brugia malayi jmjC domain containing protein 0.004 0.0314 0.0434
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0412 0.0459
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0046 0.0052
Loa Loa (eye worm) glutaminase 2 0.0265 0.2824 0.5834
Brugia malayi RNA binding protein 0.0138 0.1409 0.1948
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0046 0.0064
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0072 0.023
Schistosoma mansoni cpg binding protein 0.0095 0.0929 0.1033
Loa Loa (eye worm) TAR-binding protein 0.0138 0.1409 0.2911
Schistosoma mansoni terminal deoxycytidyl transferase 0.0082 0.0785 0.0873
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0217 0.03
Trypanosoma brucei DNA polymerase kappa, putative 0.0114 0.114 0.3637
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0027 0.003
Giardia lamblia Flap structure-specific endonuclease 0.0056 0.0498 0.0602
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0433 0.1408
Brugia malayi Bromodomain containing protein 0.0079 0.0748 0.1034
Schistosoma mansoni hypothetical protein 0.0028 0.0181 0.0202
Loa Loa (eye worm) hypothetical protein 0.0016 0.0046 0.0096
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0897 0.0997
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0051 0.0434 0.0482
Mycobacterium tuberculosis Conserved hypothetical protein 0.0082 0.0785 0.4702
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0589 0.1878
Trypanosoma brucei kinesin, putative 0.0019 0.0079 0.0253
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.058 0.0645
Mycobacterium ulcerans DNA polymerase IV 0.0114 0.114 0.4036
Loa Loa (eye worm) hypothetical protein 0.0049 0.0412 0.0852
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0072 0.0114
Trypanosoma brucei DNA polymerase kappa, putative 0.0114 0.114 0.3637
Schistosoma mansoni nuclear receptor 0.0014 0.0027 0.003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0031 0.0064
Entamoeba histolytica calpain large subunit domain III containing protein 0.0019 0.0079 0.0096
Schistosoma mansoni smad1 5 8 and 0.0018 0.0065 0.0072
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0433 0.1383
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0189 0.0716
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0139 0.0452
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0115 0.1155 0.3686
Loa Loa (eye worm) histone methyltransferase 0.002 0.0094 0.0193
Echinococcus multilocularis flap endonuclease 1 0.0056 0.0498 0.0553
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.009 0.0873 0.5282
Brugia malayi TAR-binding protein 0.0138 0.1409 0.1948
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.0051 0.0057
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0055 0.0061
Loa Loa (eye worm) CXXC zinc finger family protein 0.009 0.0872 0.18
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0063 0.0576 0.0641
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.033 0.033
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0205 0.0284
Trypanosoma brucei hypothetical protein 0.0115 0.1155 0.3686
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0082 0.0785 0.0873
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0029 0.0192 0.0612
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3078 1
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0027 0.003
Brugia malayi Calcitonin receptor-like protein seb-1 0.016 0.1654 0.2287
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0433 0.0524
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.0917 0.102
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0214 0.2257 0.2732
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0057
Plasmodium vivax flap endonuclease 1, putative 0.0056 0.0498 0.1888
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0027 0.003
Brugia malayi MH1 domain containing protein 0.0018 0.0065 0.009
Echinococcus multilocularis chromobox protein 1 0.0069 0.0634 0.0705
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0205 0.0228
Schistosoma mansoni tar DNA-binding protein 0.0138 0.1409 0.1567
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.0019 0.0082 0.0262
Brugia malayi Telomerase reverse transcriptase 0.066 0.7233 1
Echinococcus granulosus geminin 0.0339 0.3649 0.4057
Schistosoma mansoni tar DNA-binding protein 0.0138 0.1409 0.1567
Brugia malayi RNA recognition motif domain containing protein 0.0138 0.1409 0.1948
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0153 0.017
Onchocerca volvulus 0.009 0.0872 0.0872
Trypanosoma brucei DNA polymerase IV, putative 0.0114 0.114 0.3637
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0072 0.023
Trypanosoma brucei DNA damage repair protein, putative 0.0025 0.0153 0.0489
Brugia malayi Heterochromatin protein 1 0.0069 0.0634 0.0876
Loa Loa (eye worm) hypothetical protein 0.0063 0.0576 0.119
Schistosoma mansoni hypothetical protein 0.0051 0.0434 0.0482
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3078 1
Brugia malayi RNA, U transporter 1 0.0079 0.0755 0.1044
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0205 0.0228
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0433 0.1383
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0027 0.003
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0115 0.1155 0.3686
Giardia lamblia Fructose-bisphosphate aldolase 0.0287 0.3078 0.3725
Trypanosoma cruzi DNA polymerase eta, putative 0.0113 0.1125 0.3589
Loa Loa (eye worm) hypothetical protein 0.0037 0.0285 0.0589
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0392 0.0436
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0046 0.0052
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0274 0.0767
Mycobacterium ulcerans hypothetical protein 0.0025 0.0153 0.0542
Echinococcus granulosus dnaJ subfamily B 0.0817 0.8993 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0057
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0205 0.0228
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.1436 0.5086
Schistosoma mansoni hypothetical protein 0.0078 0.0737 0.082
Brugia malayi calpain 5 0.0019 0.0079 0.0109
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0221 0.0706
Loa Loa (eye worm) glutaminase 0.0265 0.2824 0.5834
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0314 0.0648
Brugia malayi hypothetical protein 0.0028 0.0182 0.0251
Schistosoma mansoni hypothetical protein 0.002 0.0095 0.0106
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0027 0.0057
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.1154 0.4379
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0433 0.1408
Echinococcus granulosus flap endonuclease 1 0.0056 0.0498 0.0553
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0139 0.0452
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0205 0.0228
Schistosoma mansoni hypothetical protein 0.0298 0.3197 0.3555
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0037 0.0285 0.0317
Trypanosoma brucei unspecified product 0.0106 0.1052 0.3356
Echinococcus multilocularis disco interacting protein 2 0.0037 0.0285 0.0317
Schistosoma mansoni bromodomain containing protein 0.0067 0.0619 0.0689
Brugia malayi hypothetical protein 0.0016 0.0046 0.0064
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0027 0.003
Echinococcus granulosus GPCR family 2 0.0051 0.0434 0.0482
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0205 0.0284
Brugia malayi nuclear hormone receptor 0.0014 0.0027 0.0038
Echinococcus multilocularis smad 0.0018 0.0065 0.0072
Trypanosoma brucei DNA polymerase kappa, putative 0.0114 0.114 0.3637
Giardia lamblia DNA damage repair protein 0.0025 0.0153 0.0185
Echinococcus granulosus chromobox protein 1 0.0069 0.0634 0.0705
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0465 0.0517
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0056 0.0062
Loa Loa (eye worm) calpain family protein 1 0.0063 0.0576 0.119
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0205 0.0228
Entamoeba histolytica hypothetical protein 0.0078 0.0737 0.0892
Echinococcus multilocularis microtubule associated protein 2 0.0679 0.7446 0.828
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0027 0.003
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0067 0.0612 0.0681
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0027 0.003
Trichomonas vaginalis DNA helicase recq, putative 0.0054 0.0473 0.1538
Echinococcus granulosus hypothetical protein 0.0028 0.0181 0.0202
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0072 0.0234
Echinococcus multilocularis calpain 5 0.0019 0.0079 0.0088
Leishmania major mitochondrial DNA polymerase beta 0.0292 0.3134 1
Schistosoma mansoni calpain (C02 family) 0.0019 0.0079 0.0088
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0433 0.1408
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0057
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0205 0.0228
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0189 0.021
Trypanosoma cruzi kinesin, putative 0.0019 0.0079 0.0253
Loa Loa (eye worm) hypothetical protein 0.0028 0.0182 0.0375
Brugia malayi Importin beta-1 subunit 0.0028 0.018 0.0249
Loa Loa (eye worm) hypothetical protein 0.0016 0.0046 0.0096
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0205 0.0228
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0051 0.0106
Echinococcus multilocularis importin subunit beta 1 0.0028 0.018 0.0201
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0189 0.021
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0029 0.0192 0.0612
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0067 0.0612 0.0681
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0027 0.003
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0433 0.0482
Trichomonas vaginalis STE family protein kinase 0.0073 0.0689 0.2238
Echinococcus multilocularis zinc finger protein 0.0024 0.0139 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0153 0.0489
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0274 0.0875
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.0019 0.0022
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0037 0.0278 0.1053
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0465 0.0517
Brugia malayi Latrophilin receptor protein 2 0.0051 0.0434 0.0599
Echinococcus granulosus disco interacting protein 2 0.0037 0.0285 0.0317
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0072 0.0149
Trichomonas vaginalis chromobox protein, putative 0.0041 0.033 0.1072
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0027 0.0038
Echinococcus granulosus DNA methyltransferase 2, putative 0.0019 0.0082 0.0091
Loa Loa (eye worm) calpain family protein 1 0.0045 0.0366 0.0755
Echinococcus granulosus dna polymerase kappa 0.0114 0.114 0.1267
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0027 0.003
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0138 0.1409 0.2911
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0138 0.1414 0.4512
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0115 0.1155 0.3686
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.3078 0.3725
Plasmodium vivax SET domain protein, putative 0.0032 0.0225 0.0854
Loa Loa (eye worm) hypothetical protein 0.0047 0.0392 0.0811
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0172 0.056
Mycobacterium ulcerans glutaminase 0.0265 0.2824 1
Schistosoma mansoni chromobox protein 0.0069 0.0634 0.0705
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0095 0.0197
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0205 0.0424
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0205 0.0654
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0072 0.2626
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0298 0.0298
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0274 0.0305
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.0019 0.0082 0.0312
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.2183 0.4508
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0274 0.0875
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0027 0.003
Entamoeba histolytica hypothetical protein 0.0023 0.0121 0.0147
Leishmania major importin beta-1 subunit, putative 0.0023 0.0121 0.0274
Onchocerca volvulus Alhambra homolog 0.0029 0.0189 0.0189
Brugia malayi conserved hypotetical protein 0.0014 0.0027 0.0038
Loa Loa (eye worm) MBCTL1 0.0053 0.0465 0.096
Trypanosoma cruzi DNA polymerase eta, putative 0.0056 0.0493 0.1573
Brugia malayi MH2 domain containing protein 0.0258 0.2752 0.3804
Schistosoma mansoni calpain C (C02 family) 0.0019 0.0079 0.0088
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0314 0.0349
Schistosoma mansoni hypothetical protein 0.0817 0.8993 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0094 0.0104
Mycobacterium ulcerans hypothetical protein 0.0154 0.1589 0.5625
Brugia malayi Pre-SET motif family protein 0.0032 0.0225 0.0311
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0205 0.0284
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0221 0.0839
Brugia malayi hypothetical protein 0.0019 0.0086 0.0119
Echinococcus granulosus calpain 5 0.0019 0.0079 0.0088
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0057
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0057
Echinococcus granulosus calpain A 0.0067 0.0612 0.0681
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0082 0.0785 0.1622
Trichomonas vaginalis chromobox protein, putative 0.0041 0.033 0.1072
Echinococcus multilocularis muscleblind protein 1 0.0445 0.4841 0.5383
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0589 0.1878
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0221 0.0246
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0433 0.128
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0189 0.021
Brugia malayi MH2 domain containing protein 0.0018 0.0065 0.009
Loa Loa (eye worm) flap endonuclease-1 0.0056 0.0498 0.1028
Brugia malayi hypothetical protein 0.003 0.0205 0.0283
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0027 0.0038
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0115 0.1155 0.3611
Schistosoma mansoni hypothetical protein 0.0339 0.3649 0.4057
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0056 0.0498 0.1588
Schistosoma mansoni glutaminase 0.0265 0.2824 0.314
Echinococcus granulosus muscleblind protein 0.0445 0.4841 0.5383
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0205 0.0228
Loa Loa (eye worm) hypothetical protein 0.003 0.0205 0.0423
Trypanosoma cruzi ISWI complex protein 0.0015 0.0037 0.0117
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0055 0.0061
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.018 0.0576
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0013 0.0012 0.0047
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0115 0.1155 0.3686
Trypanosoma brucei DNA polymerase IV, putative 0.0114 0.114 0.3637
Loa Loa (eye worm) hypothetical protein 0.0045 0.0366 0.0755
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0314 0.0349
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0048 0.04 0.1517
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0118 0.0449
Brugia malayi MAP kinase sur-1 0.0051 0.0433 0.0599
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0055 0.0061

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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