Detailed information for compound 1015653

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 290.313 | Formula: C12H22N2O6
  • H donors: 4 H acceptors: 5 LogP: -3.16 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCOC(=O)[C@@H]([C@H](O)C)NC(=O)[C@H](CC(=O)O)N
  • InChi: 1S/C12H22N2O6/c1-3-4-5-20-12(19)10(7(2)15)14-11(18)8(13)6-9(16)17/h7-8,10,15H,3-6,13H2,1-2H3,(H,14,18)(H,16,17)/t7-,8+,10-/m1/s1
  • InChiKey: LKALYQSHEGGNED-KHQFGBGNSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0087 0.0174 0.0203
Schistosoma mansoni hypothetical protein 0.0174 0.046 0.0591
Onchocerca volvulus 0.0103 0.0226 0.023
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0063 0.0093 0.0113
Toxoplasma gondii hypothetical protein 0.0061 0.0089 0.0491
Leishmania major heat shock protein 83-1 0.0074 0.0132 0.0292
Mycobacterium ulcerans acyl-CoA synthetase 0.0124 0.0296 0.5204
Schistosoma mansoni nephrin 0.0112 0.0256 0.0325
Loa Loa (eye worm) hypothetical protein 0.0112 0.0256 0.0249
Loa Loa (eye worm) TK/KIN16 protein kinase 0.3063 1 1
Schistosoma mansoni hypothetical protein 0.0174 0.046 0.0591
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0178 0.0473 1
Brugia malayi Leucine Rich Repeat family protein 0.0049 0.0049 0.0049
Leishmania major hypothetical protein, conserved 0.0074 0.0132 0.0292
Loa Loa (eye worm) hypothetical protein 0.018 0.0481 0.0475
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Loa Loa (eye worm) projectin 0.0049 0.0049 0.0042
Echinococcus granulosus GPCR family 2 0.0049 0.0047 0.0054
Loa Loa (eye worm) hypothetical protein 0.0154 0.0396 0.0389
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0154 0.0396 0.0389
Trichomonas vaginalis DNA topoisomerase II, putative 0.0074 0.0132 0.1634
Schistosoma mansoni pyruvate dehydrogenase 0.1262 0.4054 0.5283
Trichomonas vaginalis replication factor C large subunit, putative 0.0053 0.0062 0.0726
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0062 0.1197
Schistosoma mansoni jumonji domain containing protein 0.0153 0.0391 0.0502
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0087 0.0174 0.039
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0141 0.175
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0053 0.0062 0.0439
Brugia malayi Heparan sulfate 0.0063 0.0093 0.0093
Schistosoma mansoni titin 0.0049 0.0049 0.0055
Trypanosoma brucei developmentally regulated phosphoprotein 0.1337 0.43 1
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0007 0.0007
Onchocerca volvulus 0.005 0.005 0.0046
Loa Loa (eye worm) hypothetical protein 0.0077 0.0141 0.0134
Echinococcus multilocularis peroxidasin 0.0112 0.0256 0.0302
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0062 0.0726
Schistosoma mansoni hypothetical protein 0.0049 0.0049 0.0055
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0205 0.0563 0.0726
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0133 0.0324 0.0385
Brugia malayi basement membrane proteoglycan precursor 0.0063 0.0093 0.0093
Brugia malayi hypothetical protein 0.0063 0.0093 0.0093
Schistosoma mansoni hypothetical protein 0.0049 0.0049 0.0055
Loa Loa (eye worm) hypothetical protein 0.0244 0.0693 0.0687
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.042 0.1273 1
Echinococcus multilocularis Immunoglobulin subtype 0.0063 0.0093 0.0106
Schistosoma mansoni heat shock protein 0.0074 0.0132 0.0163
Trypanosoma cruzi heat shock protein 85, putative 0.0074 0.0132 0.0292
Brugia malayi Prion-like- 0.0049 0.0049 0.0049
Loa Loa (eye worm) CAMK protein kinase 0.005 0.005 0.0044
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0062 0.0092 0.0104
Leishmania major heat shock protein 83-1 0.0074 0.0132 0.0292
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0175 0.0463 0.0457
Loa Loa (eye worm) hypothetical protein 0.0048 0.0044 0.0037
Loa Loa (eye worm) hypothetical protein 0.042 0.1273 0.1267
Schistosoma mansoni netrin receptor unc5 0.0063 0.0093 0.0113
Toxoplasma gondii ATPase, AAA family protein 0.0053 0.0062 0.0334
Loa Loa (eye worm) hypothetical protein 0.0074 0.0132 0.0125
Plasmodium falciparum DNA gyrase subunit B 0.0074 0.0132 0.2681
Mycobacterium leprae conserved hypothetical protein 0.0077 0.0141 0.287
Onchocerca volvulus Tyrosine kinase homolog 0.2917 0.9517 1
Echinococcus granulosus tar DNA binding protein 0.0207 0.0571 0.0737
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0062 0.0335
Loa Loa (eye worm) hypothetical protein 0.0051 0.0056 0.005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0063 0.0093 0.0093
Schistosoma mansoni hypothetical protein 0.0171 0.0449 0.0578
Trypanosoma cruzi heat shock protein 85, putative 0.0074 0.0132 0.0292
Loa Loa (eye worm) hypothetical protein 0.0105 0.0235 0.0228
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0087 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0186
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0112 0.0256 0.0249
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0074 0.0132 0.0832
Leishmania major 4-coumarate:coa ligase-like protein 0.0124 0.0296 0.0674
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.1337 0.43 0.5604
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0074 0.0132 0.075
Leishmania major heat shock protein 83-1 0.0074 0.0132 0.0292
Brugia malayi Disorganized muscle protein 1 0.0049 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0053 0.0062 0.0056
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Onchocerca volvulus 0.0067 0.0106 0.0105
Toxoplasma gondii heat shock protein HSP90 0.0074 0.0132 0.075
Trichomonas vaginalis endoplasmin, putative 0.0074 0.0132 0.1634
Schistosoma mansoni cellular tumor antigen P53 0.0196 0.0532 0.0686
Loa Loa (eye worm) hypothetical protein 0.0053 0.0063 0.0056
Leishmania major DNA topoisomerase ii 0.0074 0.0132 0.0292
Loa Loa (eye worm) hypothetical protein 0.0077 0.0141 0.0134
Schistosoma mansoni peptidase Clp (S14 family) 0.0178 0.0473 0.0609
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0186
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0074 0.0132 0.0832
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0236 0.0665 0.0659
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0065 0.0065
Schistosoma mansoni hypothetical protein 0.0171 0.0449 0.0578
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0049 0.0049 0.0042
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0186
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Leishmania major 4-coumarate:coa ligase-like protein 0.0124 0.0296 0.0674
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0222 0.0281
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0074 0.0132 0.1691
Chlamydia trachomatis DNA gyrase subunit B 0.0074 0.0132 0.1691
Echinococcus granulosus lysine specific demethylase 5A 0.0107 0.024 0.0306
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0053 0.0062 0.0062
Schistosoma mansoni tar DNA-binding protein 0.0207 0.0571 0.0736
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0175 0.0464 0.0598
Schistosoma mansoni peroxidasin 0.0063 0.0093 0.0113
Brugia malayi protein unc-22 0.005 0.005 0.005
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0077 0.0141 0.2409
Brugia malayi Endoplasmin precursor 0.0074 0.0132 0.0132
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0062 0.013
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0074 0.0132 0.1634
Schistosoma mansoni hypothetical protein 0.029 0.0843 0.1091
Loa Loa (eye worm) hypothetical protein 0.0049 0.0047 0.0041
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0063 0.0093 0.0106
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0077 0.0141 0.0891
Mycobacterium leprae Probable lipase LipE 0.0077 0.0141 0.287
Brugia malayi MH2 domain containing protein 0.0134 0.033 0.033
Schistosoma mansoni hypothetical protein 0.0112 0.0257 0.0327
Schistosoma mansoni roundabout 0.0112 0.0256 0.0325
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0044 0.0039
Entamoeba histolytica acyl-CoA synthetase, putative 0.0124 0.0296 0.2287
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0077 0.0141 0.0891
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Schistosoma mansoni topbp1 0.0053 0.0062 0.0073
Echinococcus multilocularis titin 0.0049 0.0049 0.0051
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0061 0.0089 0.1756
Trichomonas vaginalis receptor histidine kinase, putative 0.0074 0.0132 0.1634
Mycobacterium tuberculosis Conserved protein 0.0077 0.0141 0.0891
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0178 0.0473 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0124 0.0296 0.5204
Entamoeba histolytica hypothetical protein 0.0112 0.0257 0.198
Schistosoma mansoni hypothetical protein 0.0063 0.0093 0.0113
Schistosoma mansoni neuroglian 0.0112 0.0256 0.0325
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0467 0.1429 0.3314
Brugia malayi AMP-binding enzyme family protein 0.0124 0.0296 0.0296
Brugia malayi hypothetical protein 0.0152 0.0388 0.0388
Onchocerca volvulus Putative titin 0.0049 0.0049 0.0044
Entamoeba histolytica hypothetical protein 0.0112 0.0257 0.198
Trypanosoma cruzi heat shock protein 90, putative 0.0074 0.0132 0.0292
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0053 0.0062 0.0726
Brugia malayi Probable DNA topoisomerase II 0.0074 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0053 0.0062 0.0056
Mycobacterium ulcerans acyl-CoA synthetase 0.0124 0.0296 0.5204
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0053 0.0063 0.0074
Mycobacterium ulcerans lipase LipD 0.0077 0.0141 0.2409
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0087
Echinococcus multilocularis roundabout 2 0.0112 0.0256 0.0302
Brugia malayi Immunoglobulin I-set domain containing protein 0.005 0.005 0.005
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0102 0.0222 0.0261
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0074 0.0132 0.1691
Echinococcus multilocularis Niemann Pick C1 protein 0.06 0.1868 0.2258
Echinococcus granulosus tumor protein p63 0.1336 0.4297 0.56
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Schistosoma mansoni tyrosine kinase 0.0125 0.0299 0.0382
Trichomonas vaginalis esterase, putative 0.0077 0.0141 0.175
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Leishmania major heat shock protein 83-1 0.0074 0.0132 0.0292
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0141 0.175
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0074 0.0132 0.0832
Loa Loa (eye worm) hypothetical protein 0.1337 0.43 0.4296
Brugia malayi mbt repeat family protein 0.0048 0.0044 0.0044
Echinococcus granulosus heat shock protein 90 0.0074 0.0132 0.0164
Schistosoma mansoni tar DNA-binding protein 0.0207 0.0571 0.0736
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0188 0.0506 0.0653
Echinococcus granulosus peroxidasin 0.0112 0.0256 0.0325
Loa Loa (eye worm) hypothetical protein 0.0133 0.0324 0.0318
Schistosoma mansoni netrin receptor unc5 0.0063 0.0093 0.0113
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0078 0.0935
Onchocerca volvulus 0.0049 0.0049 0.0044
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0098 0.0208 0.0208
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0124 0.0296 0.5204
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0077 0.0141 0.0891
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0124 0.0296 0.1924
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0059 0.0082 0.0076
Schistosoma mansoni titin 0.0112 0.0256 0.0325
Plasmodium vivax replication factor C subunit 1, putative 0.0053 0.0062 0.1192
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0062 0.013
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0074 0.0132 0.2681
Loa Loa (eye worm) hypothetical protein 0.0133 0.0324 0.0318
Trichomonas vaginalis heat shock protein, putative 0.0074 0.0132 0.1634
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0175 0.0464 0.0555
Loa Loa (eye worm) hypothetical protein 0.0133 0.0324 0.0318
Onchocerca volvulus 0.0268 0.0773 0.0805
Toxoplasma gondii DNA topoisomerase 2, putative 0.0074 0.0132 0.075
Entamoeba histolytica hypothetical protein 0.0112 0.0257 0.198
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0354 0.0454
Loa Loa (eye worm) hypothetical protein 0.0077 0.0141 0.0134
Loa Loa (eye worm) jmjC domain-containing protein 0.0107 0.024 0.0234
Brugia malayi Fibronectin type III domain containing protein 0.0133 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0504 0.1551 0.1545
Plasmodium vivax acyl-CoA synthetase, putative 0.0093 0.0192 0.3982
Trypanosoma brucei heat shock protein, putative 0.0074 0.0132 0.0292
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0036 0.0007 0.0007
Schistosoma mansoni pyruvate dehydrogenase 0.1337 0.43 0.5604
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Brugia malayi beta-lactamase family protein 0.0077 0.0141 0.0141
Echinococcus granulosus netrin receptor unc 5 0.0063 0.0093 0.0114
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0133 0.0324 0.0414
Schistosoma mansoni hypothetical protein 0.0174 0.046 0.0591
Leishmania major 4-coumarate:coa ligase-like protein 0.0124 0.0296 0.0674
Echinococcus multilocularis Immunoglobulin 0.0063 0.0093 0.0106
Schistosoma mansoni lamin 0.0111 0.0252 0.032
Onchocerca volvulus 0.0111 0.0252 0.0258
Schistosoma mansoni intermediate filament proteins 0.0111 0.0252 0.032
Schistosoma mansoni pyruvate dehydrogenase 0.1262 0.4054 0.5283
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0098 0.0208 0.0202
Echinococcus granulosus Immunoglobulin 0.0133 0.0324 0.0415
Echinococcus granulosus Protein patched homolog 1 0.018 0.0481 0.062
Leishmania major heat shock protein 83-1 0.0074 0.0132 0.0292
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.018 0.0481 0.0475
Schistosoma mansoni cell adhesion molecule 0.0063 0.0093 0.0113
Schistosoma mansoni hypothetical protein 0.0049 0.0047 0.0053
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0102 0.0222 0.0281
Plasmodium falciparum DNA topoisomerase 2 0.0074 0.0132 0.2681
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0058 0.0078 0.0167
Schistosoma mansoni cell adhesion molecule 0.0112 0.0256 0.0325
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0007 0.0007
Leishmania major heat shock protein 83-1 0.0074 0.0132 0.0292
Echinococcus granulosus Immunoglobulin subtype 0.0063 0.0093 0.0114
Loa Loa (eye worm) TOPoisomerase family member 0.0074 0.0132 0.0125
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0074 0.0132 0.0832
Onchocerca volvulus 0.0077 0.0141 0.0141
Entamoeba histolytica heat shock protein 90, putative 0.0074 0.0132 0.0989
Schistosoma mansoni heat shock protein 0.0074 0.0132 0.0163
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Echinococcus granulosus hemicentin 1 0.0112 0.0256 0.0325
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0065 0.0077
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0074 0.0132 0.2681
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0063 0.0093 0.0087
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0112 0.0256 0.0302
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0178 0.0473 0.0567
Echinococcus multilocularis hemicentin 1 0.0112 0.0256 0.0302
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0492 0.1511 1
Brugia malayi Immunoglobulin domain containing protein 0.0063 0.0093 0.0093
Echinococcus multilocularis Niemann Pick C1 protein 0.042 0.1273 0.1536
Leishmania major heat shock protein 83-1 0.0074 0.0132 0.0292
Onchocerca volvulus 0.0049 0.0049 0.0044
Loa Loa (eye worm) hypothetical protein 0.0053 0.0062 0.0056
Leishmania major heat shock protein 83-1 0.0074 0.0132 0.0292
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0074 0.0132 0.225
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Echinococcus multilocularis neuroglian 0.0182 0.0486 0.0582
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0205 0.0563 0.1296
Schistosoma mansoni cell adhesion molecule 0.0049 0.0049 0.0055
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Loa Loa (eye worm) endoplasmin 0.0074 0.0132 0.0125
Loa Loa (eye worm) hypothetical protein 0.0124 0.0296 0.029
Loa Loa (eye worm) one IG domain family member 0.0049 0.0049 0.0042
Loa Loa (eye worm) MH2 domain-containing protein 0.0134 0.033 0.0324
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0049 0.0049 0.0042
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.0368 0.0438
Schistosoma mansoni hypothetical protein 0.0063 0.0093 0.0113
Loa Loa (eye worm) hypothetical protein 0.0133 0.0324 0.0318
Echinococcus granulosus titin 0.005 0.005 0.0057
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0049 0.0049 0.0055
Schistosoma mansoni hypothetical protein 0.0049 0.0049 0.0055
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0053 0.0062 0.0726
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0061 0.0089 0.1756
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0093 0.0192 0.3342
Echinococcus granulosus intermediate filament protein 0.0111 0.0252 0.0321
Schistosoma mansoni hypothetical protein 0.0063 0.0093 0.0113
Plasmodium falciparum endoplasmin, putative 0.0074 0.0132 0.2681
Echinococcus granulosus jumonji domain containing protein 0.0046 0.0037 0.004
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0074 0.0132 0.0832
Brugia malayi Melibiase family protein 0.0068 0.011 0.011
Echinococcus multilocularis tumor protein p63 0.1336 0.4297 0.5205
Schistosoma mansoni hypothetical protein 0.0049 0.0049 0.0055
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0049 0.0049 0.0042
Echinococcus granulosus heat shock protein 0.0074 0.0132 0.0164
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0063 0.0093 0.0113
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0141 0.175
Echinococcus multilocularis survival motor neuron protein 1 0.0504 0.1551 0.1873
Brugia malayi Prion-like- 0.0112 0.0256 0.0256
Schistosoma mansoni tar DNA-binding protein 0.0207 0.0571 0.0736
Brugia malayi Immunoglobulin I-set domain containing protein 0.0063 0.0093 0.0093
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0065 0.0077
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0087 0.0174 0.2183
Brugia malayi TAR-binding protein 0.0207 0.0571 0.0571
Mycobacterium ulcerans two component sensor kinase MprB 0.0074 0.0132 0.225
Loa Loa (eye worm) hypothetical protein 0.0051 0.0056 0.005
Echinococcus multilocularis hemicentin 1 0.0112 0.0256 0.0302
Plasmodium vivax DNA gyrase subunit B, putative 0.0074 0.0132 0.2681
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0058 0.0078 0.0167
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0061 0.0089 0.1756
Mycobacterium ulcerans beta-lactamase 0.0077 0.0141 0.2409
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0074 0.0132 0.0832
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0205 0.0563 0.0675
Brugia malayi Pre-SET motif family protein 0.0236 0.0665 0.0665
Brugia malayi hypothetical protein 0.0053 0.0062 0.0062
Echinococcus granulosus neuroglian 0.0112 0.0256 0.0325
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0063 0.0093 0.0087
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0074 0.0132 0.0292
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0112 0.0256 0.0325
Plasmodium falciparum acyl-CoA synthetase 0.0093 0.0192 0.3982
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0028 0.0028
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0176 0.1124
Brugia malayi Immunoglobulin I-set domain containing protein 0.0112 0.0256 0.0256
Brugia malayi Immunoglobulin I-set domain containing protein 0.0112 0.0256 0.0256
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0074 0.0132 0.0832
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0049 0.0049 0.0042
Mycobacterium tuberculosis Conserved protein 0.0074 0.0132 0.0832
Echinococcus granulosus insulin growth factor binding 0.0049 0.0049 0.0055
Schistosoma mansoni cell adhesion molecule 0.0063 0.0093 0.0113
Plasmodium vivax hypothetical protein, conserved 0.0077 0.0141 0.287
Echinococcus granulosus roundabout 2 0.0112 0.0256 0.0325
Echinococcus granulosus mitogen activated protein kinase 0.0058 0.0078 0.0094
Echinococcus granulosus Niemann Pick C1 protein 0.06 0.1868 0.2429
Loa Loa (eye worm) hypothetical protein 0.0112 0.0256 0.0249
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0078 0.0167
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0176 0.1124
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0074 0.0132 0.225
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0049 0.0049 0.0051
Toxoplasma gondii melibiase subfamily protein 0.0102 0.0222 0.129
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0063 0.0093 0.0114
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0087 0.0174 0.0218
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0087 0.0174 1
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0007 0.0007
Schistosoma mansoni vesicular amine transporter 0.0133 0.0324 0.0414
Onchocerca volvulus 0.0152 0.0388 0.0401
Chlamydia trachomatis DNA gyrase subunit B 0.0074 0.0132 0.1691
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0074 0.0132 0.0292
Brugia malayi beta-lactamase family protein 0.0077 0.0141 0.0141
Trypanosoma brucei heat shock protein, putative 0.0074 0.0132 0.0292
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0062 0.1197
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0087 0.0174 0.0219
Leishmania major heat shock protein 83-1 0.0074 0.0132 0.0292
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0205 0.0563 0.3698
Echinococcus granulosus ubiquitin specific protease 41 0.0087 0.0174 0.0219
Echinococcus multilocularis mitogen activated protein kinase 3 0.0058 0.0078 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0141 0.0312
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0178 0.0473 0.8392
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0047 0.0054
Loa Loa (eye worm) LAD-2 short isoform 0.0063 0.0093 0.0087
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0062 0.1197
Brugia malayi Immunoglobulin domain containing protein 0.0063 0.0093 0.0093
Schistosoma mansoni nephrin 0.0182 0.0486 0.0626
Schistosoma mansoni hypothetical protein 0.0049 0.0047 0.0053
Giardia lamblia Kinase, CMGC MAPK 0.0058 0.0078 0.3939
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0093 0.0192 0.3168
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0058 0.0078 0.0167
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0074 0.0132 0.2681
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0087 0.0174 0.0218
Echinococcus multilocularis down syndrome cell adhesion 0.0049 0.0049 0.0051
Leishmania major hypothetical protein, conserved 0.0077 0.0141 0.0312
Brugia malayi Pax transcription activation domain interacting protein 0.0053 0.0062 0.0062
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0178 0.0473 1
Loa Loa (eye worm) hypothetical protein 0.0112 0.0256 0.0249
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0074 0.0132 0.225
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0058 0.0078 0.0167
Mycobacterium ulcerans putative regultory protein 0.0074 0.0132 0.225
Echinococcus multilocularis insulin growth factor binding 0.0049 0.0049 0.0051
Onchocerca volvulus 0.0111 0.0252 0.0258
Trypanosoma brucei heat shock protein, putative 0.0074 0.0132 0.0292
Mycobacterium tuberculosis Probable hydrolase 0.0077 0.0141 0.0891
Schistosoma mansoni nephrin related 0.0063 0.0093 0.0113
Echinococcus multilocularis geminin 0.0171 0.0449 0.0537
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0467 0.1429 0.3314
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0139 0.0345 0.0411
Echinococcus multilocularis twitchin 0.005 0.005 0.0053
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0176 0.1124
Trypanosoma cruzi DNA topoisomerase II, putative 0.0074 0.0132 0.0292
Loa Loa (eye worm) hypothetical protein 0.0152 0.0388 0.0382
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0208 0.0263
Echinococcus multilocularis netrin receptor unc 5 0.0063 0.0093 0.0106
Loa Loa (eye worm) hypothetical protein 0.0077 0.0141 0.0134
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Schistosoma mansoni titin 0.0049 0.0049 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.018 0.0481 0.6196
Loa Loa (eye worm) hypothetical protein 0.0087 0.0174 0.0167
Mycobacterium tuberculosis Probable two component sensor kinase 0.0074 0.0132 0.0832
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0074 0.0132 0.0132
Brugia malayi AMP-binding enzyme family protein 0.0124 0.0296 0.0296
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0049 0.0049 0.0055
Loa Loa (eye worm) TAR-binding protein 0.0207 0.0571 0.0565
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0467 0.1429 0.3314
Echinococcus granulosus geminin 0.0171 0.0449 0.0578
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0063 0.0093 0.0113
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0074 0.0132 0.1634
Leishmania major heat shock protein 83-1 0.0074 0.0132 0.0292
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0087 0.0174 0.039
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0112 0.0257 0.0251
Onchocerca volvulus 0.0196 0.0532 0.0552
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0112 0.0257 0.0304
Echinococcus granulosus titin 0.0049 0.0049 0.0055
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0087 0.0174 0.2183
Echinococcus multilocularis protein patched 0.018 0.0481 0.0576
Schistosoma mansoni hypothetical protein 0.0174 0.046 0.0591
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0044 0.0048
Brugia malayi DKFZp564C0469 protein 0.0053 0.0062 0.0062
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0074 0.0132 0.0132
Schistosoma mansoni septate junction protein 0.0112 0.0256 0.0325
Schistosoma mansoni serine/threonine protein kinase 0.005 0.005 0.0057
Schistosoma mansoni hypothetical protein 0.0103 0.0226 0.0286
Echinococcus multilocularis GPCR, family 2 0.0049 0.0047 0.005
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0102 0.0222 0.0261
Echinococcus granulosus tyrosine protein kinase otk 0.0112 0.0256 0.0325
Mycobacterium leprae Probable two component sensor kinase MprB 0.0074 0.0132 0.2681
Echinococcus multilocularis lysine specific demethylase 5A 0.0107 0.024 0.0284
Schistosoma mansoni septate junction protein 0.0063 0.0093 0.0113
Onchocerca volvulus 0.0049 0.0049 0.0044
Schistosoma mansoni jumonji/arid domain-containing protein 0.0107 0.024 0.0305
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0058 0.0078 0.0072
Loa Loa (eye worm) animal heme peroxidase 0.0049 0.0049 0.0042
Echinococcus multilocularis 0.0049 0.0049 0.0051
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0061 0.0089 0.0641
Echinococcus multilocularis tar DNA binding protein 0.0207 0.0571 0.0685
Mycobacterium ulcerans DNA gyrase subunit B 0.0074 0.0132 0.225
Onchocerca volvulus 0.0077 0.0141 0.0141
Mycobacterium ulcerans aldehyde dehydrogenase 0.0139 0.0345 0.6089
Mycobacterium tuberculosis Probable esterase LipL 0.0077 0.0141 0.0891
Schistosoma mansoni lamin 0.0111 0.0252 0.032
Trichomonas vaginalis receptor histidine kinase, putative 0.0074 0.0132 0.1634
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0074 0.0132 0.1691
Trypanosoma brucei heat shock protein 90, putative 0.0074 0.0132 0.0292
Loa Loa (eye worm) hypothetical protein 0.0195 0.0531 0.0525
Brugia malayi Immunoglobulin I-set domain containing protein 0.0112 0.0256 0.0256
Schistosoma mansoni hypothetical protein 0.0063 0.0093 0.0113
Schistosoma mansoni hemicentin 0.0049 0.0049 0.0055
Echinococcus multilocularis musashi 0.0111 0.0252 0.0298
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0195 0.0531 0.0685
Schistosoma mansoni serine/threonine protein kinase 0.005 0.005 0.0057
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0139 0.0345 0.0789
Toxoplasma gondii aldehyde dehydrogenase 0.0139 0.0345 0.2031
Loa Loa (eye worm) hypothetical protein 0.0112 0.0256 0.0249
Entamoeba histolytica hypothetical protein 0.0053 0.0062 0.0439
Brugia malayi Intermediate filament tail domain containing protein 0.0111 0.0252 0.0252
Trypanosoma brucei protein kinase, putative 0.0058 0.0078 0.0167
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0132 0.2681
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0178 0.0473 1
Mycobacterium tuberculosis Conserved protein 0.0077 0.0141 0.0891
Brugia malayi AMP-binding enzyme family protein 0.0124 0.0296 0.0296
Loa Loa (eye worm) hypothetical protein 0.0244 0.0693 0.0687
Onchocerca volvulus 0.0049 0.0049 0.0044
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0063 0.0093 0.0106
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0112 0.0256 0.0302
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0074 0.0132 0.1634
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0063 0.0093 0.0113
Brugia malayi Immunoglobulin I-set domain containing protein 0.0063 0.0093 0.0093
Trypanosoma brucei heat shock protein 90, putative 0.0074 0.0132 0.0292
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0093 0.0192 0.1236
Trichomonas vaginalis sensor histidine kinase, putative 0.0074 0.0132 0.1634
Mycobacterium tuberculosis Probable lipase LipD 0.0077 0.0141 0.0891
Echinococcus multilocularis ubiquitin specific protease 41 0.0087 0.0174 0.0203
Echinococcus multilocularis Immunoglobulin 0.0133 0.0324 0.0385
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0068 0.011 0.135
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0112 0.0256 0.0325
Loa Loa (eye worm) hypothetical protein 0.0077 0.0141 0.0134
Brugia malayi topoisomerase 0.0053 0.0062 0.0062
Loa Loa (eye worm) transcription factor SMAD2 0.0134 0.033 0.0324
Brugia malayi kettin 0.0049 0.0049 0.0049
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0141 0.175
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0028 0.0278
Brugia malayi Immunoglobulin I-set domain containing protein 0.0112 0.0256 0.0256
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0016 0.0203
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0074 0.0132 0.1634
Loa Loa (eye worm) hypothetical protein 0.0196 0.0532 0.0526
Loa Loa (eye worm) hypothetical protein 0.0068 0.011 0.0103
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0044 0.0049
Schistosoma mansoni titin 0.0049 0.0049 0.0055
Brugia malayi kinase, mitochondrial precursor 0.1337 0.43 0.43
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0208 0.0263
Brugia malayi Immunoglobulin I-set domain containing protein 0.0112 0.0256 0.0256
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0065 0.0077
Echinococcus multilocularis replication factor c subunit 1 0.0053 0.0062 0.0068
Echinococcus multilocularis mitogen activated protein kinase 0.0058 0.0078 0.0087
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0049 0.0049 0.0042
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0062 0.013
Loa Loa (eye worm) acetyltransferase 0.0146 0.0368 0.0361
Schistosoma mansoni basigin related 0.0063 0.0093 0.0113
Echinococcus multilocularis protein dispatched 1 0.0206 0.0565 0.0678
Trypanosoma brucei heat shock protein, putative 0.0074 0.0132 0.0292
Brugia malayi Immunoglobulin I-set domain containing protein 0.0112 0.0256 0.0256
Loa Loa (eye worm) hypothetical protein 0.0074 0.0131 0.0125
Trypanosoma cruzi heat shock protein 85, putative 0.0074 0.0132 0.0292
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0044 0.0048
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0074 0.0132 0.0132
Echinococcus granulosus Niemann Pick C1 protein 0.042 0.1273 0.1653
Schistosoma mansoni patched 1 0.018 0.0481 0.0619
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0124 0.0296 0.6201
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0124 0.0296 0.5204
Echinococcus granulosus expressed conserved protein 0.0394 0.1189 0.1543
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0074 0.0132 0.1691
Echinococcus multilocularis heat shock protein 90 0.0074 0.0132 0.0152
Loa Loa (eye worm) RNA binding protein 0.0207 0.0571 0.0565
Entamoeba histolytica acyl-coA synthetase, putative 0.0124 0.0296 0.2287
Schistosoma mansoni cell adhesion molecule 0.0112 0.0256 0.0325
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.011 0.0135
Leishmania major heat shock protein 83-1 0.0074 0.0132 0.0292
Onchocerca volvulus Peroxidasin homolog 0.0049 0.0049 0.0044
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0058 0.0078 0.0167
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0112 0.0257 0.0328
Loa Loa (eye worm) disorganized muscle protein 1 0.0049 0.0049 0.0042
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0074 0.0132 0.1691
Loa Loa (eye worm) hypothetical protein 0.0053 0.0062 0.0056
Echinococcus granulosus contactin 0.0112 0.0256 0.0325
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0222 0.0281
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0028 0.0456
Schistosoma mansoni jumonji/arid domain-containing protein 0.0107 0.024 0.0305
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0077 0.0141 0.0141
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0074 0.0132 0.0292
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0049 0.0049 0.0042
Echinococcus multilocularis titin 0.0049 0.0049 0.0051
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0044 0.0049
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0112 0.0256 0.0262
Echinococcus multilocularis Immunoglobulin 0.0133 0.0324 0.0385
Echinococcus granulosus lamin 0.0111 0.0252 0.0321
Loa Loa (eye worm) TK protein kinase 0.0062 0.0092 0.0086
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0087 0.0174 0.1321
Plasmodium vivax heat shock protein 86, putative 0.0074 0.0132 0.2681
Schistosoma mansoni titin 0.0049 0.0049 0.0055
Onchocerca volvulus 0.0077 0.0141 0.0141
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0074 0.0132 0.1691
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0053 0.0062 0.0726
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0044 0.0045
Trypanosoma cruzi FHA domain containing protein, putative 0.0053 0.0062 0.013
Echinococcus granulosus survival motor neuron protein 1 0.0504 0.1551 0.2016
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0049 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0111 0.0252 0.0246
Echinococcus multilocularis neuroglian 0.0112 0.0256 0.0302
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Echinococcus granulosus Immunoglobulin 0.0063 0.0093 0.0114
Toxoplasma gondii heat shock protein 90, putative 0.0074 0.0132 0.075
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0208 0.0245
Entamoeba histolytica DNA topoisomerase II, putative 0.0074 0.0132 0.0989
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0178 0.0473 0.061
Loa Loa (eye worm) jmjC domain-containing protein 0.0068 0.011 0.0103
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0074 0.0132 0.0832
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Echinococcus multilocularis expressed conserved protein 0.0394 0.1189 0.1434
Brugia malayi hypothetical protein 0.0053 0.0062 0.0062
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0178 0.0473 1
Schistosoma mansoni cell adhesion molecule 0.0112 0.0256 0.0325
Plasmodium falciparum replication factor C subunit 1, putative 0.0053 0.0062 0.1192
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0112 0.0256 0.0302
Schistosoma mansoni titin 0.005 0.005 0.0057
Giardia lamblia Replication factor C, subunit 1 0.0053 0.0062 0.2926
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0063 0.0093 0.0106
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0047 0.0047
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0074 0.0132 0.0292
Brugia malayi Immunoglobulin I-set domain containing protein 0.0133 0.0324 0.0324
Entamoeba histolytica acyl-CoA synthetase, putative 0.0124 0.0296 0.2287
Schistosoma mansoni tar DNA-binding protein 0.0207 0.0571 0.0736
Echinococcus granulosus basement membrane specific heparan sulfate 0.0063 0.0093 0.0114
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0087
Loa Loa (eye worm) hypothetical protein 0.0124 0.0296 0.029
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0044 0.0037
Leishmania major developmentally regulated phosphoprotein-like protein 0.1337 0.43 1
Brugia malayi Immunoglobulin domain containing protein 0.0063 0.0093 0.0093
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0178 0.0473 1
Brugia malayi basement membrane proteoglycan 0.0063 0.0093 0.0093
Leishmania major heat shock protein 83-1 0.0074 0.0132 0.0292
Trypanosoma cruzi heat shock protein 90, putative 0.0074 0.0132 0.0292
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0087 0.0174 0.039
Echinococcus granulosus roundabout 2 0.0112 0.0256 0.0325
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0222 0.0281
Brugia malayi Niemann-Pick C1 protein precursor 0.042 0.1273 0.1273
Loa Loa (eye worm) heat shock protein 90 0.0074 0.0132 0.0125
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0139 0.0345 0.0442
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0047 0.005
Echinococcus granulosus low density lipoprotein receptor ldl 0.0063 0.0093 0.0114
Echinococcus granulosus roundabout 2 0.0244 0.0693 0.0897
Schistosoma mansoni basigin related 0.0063 0.0093 0.0113
Brugia malayi jmjC domain containing protein 0.0107 0.024 0.024
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0074 0.0132 0.0132
Leishmania major heat shock protein 83-1 0.0074 0.0132 0.0292
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0062 0.013
Onchocerca volvulus 0.0124 0.0296 0.0304
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0117 0.0271 0.1759
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0047 0.0041
Leishmania major heat shock protein 83-1 0.0074 0.0132 0.0292
Schistosoma mansoni endoplasmin 0.0074 0.0132 0.0163
Brugia malayi Peroxidasin 0.0112 0.0256 0.0256
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0074 0.0132 0.1634
Brugia malayi latrophilin 2 splice variant baaae 0.0105 0.0235 0.0235
Entamoeba histolytica heat shock protein 90, putative 0.0074 0.0132 0.0989
Brugia malayi MAP kinase sur-1 0.0058 0.0078 0.0078
Mycobacterium ulcerans hypothetical protein 0.0077 0.0141 0.2409
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0053 0.0062 0.013
Mycobacterium ulcerans hypothetical protein 0.0124 0.0296 0.5204
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0074 0.0132 0.225
Schistosoma mansoni hypothetical protein 0.0049 0.0049 0.0055
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0112 0.0256 0.0325
Echinococcus granulosus titin 0.005 0.005 0.0057
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0176 0.1124
Brugia malayi Probable ClpP-like protease 0.0178 0.0473 0.0473
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0208 0.0263
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0124 0.0296 0.5204
Schistosoma mansoni slit 0.0049 0.0049 0.0055
Echinococcus multilocularis lamin dm0 0.0111 0.0252 0.0298
Echinococcus granulosus peptidase Clp S14 family 0.0117 0.0271 0.0346
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0044 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0062 0.0726
Schistosoma mansoni hypothetical protein 0.0049 0.0047 0.0053
Onchocerca volvulus 0.0049 0.0049 0.0044
Onchocerca volvulus 0.2854 0.9311 0.9784
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0074 0.0132 0.0832
Schistosoma mansoni DNA topoisomerase II 0.0074 0.0132 0.0163
Mycobacterium tuberculosis Conserved protein 0.0077 0.0141 0.0891
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0065 0.0072
Loa Loa (eye worm) hypothetical protein 0.0133 0.0324 0.0318
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0063 0.0093 0.0114
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0103 0.0226 0.0226
Brugia malayi beta-lactamase 0.0077 0.0141 0.0141
Schistosoma mansoni cell adhesion molecule 0.0049 0.0049 0.0055
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.1337 0.43 0.5208
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0074 0.0132 0.225
Echinococcus granulosus leucine rich repeat containing protein 4 0.0049 0.0049 0.0055
Onchocerca volvulus 0.0048 0.0044 0.0039
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0188 0.0506 0.0606
Loa Loa (eye worm) hypothetical protein 0.0124 0.0296 0.029
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0028 0.0278
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0053 0.0062 0.0334
Onchocerca volvulus 0.0049 0.0049 0.0044
Giardia lamblia Pms1-like protein 0.0074 0.0132 0.7333
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.005 0.005 0.0044
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0117 0.0271 0.1759
Echinococcus multilocularis Immunoglobulin 0.0063 0.0093 0.0106
Loa Loa (eye worm) hypothetical protein 0.0133 0.0324 0.0318
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0087
Schistosoma mansoni hypothetical protein 0.0049 0.0047 0.0053
Loa Loa (eye worm) hypothetical protein 0.0054 0.0065 0.0059
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0049 0.0049 0.0051
Schistosoma mansoni cell adhesion molecule 0.0195 0.0531 0.0685
Echinococcus multilocularis titin 0.0049 0.0049 0.0051
Echinococcus granulosus lamin dm0 0.0111 0.0252 0.0321
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0426 0.1294 0.168
Echinococcus multilocularis tyrosine protein kinase otk 0.0112 0.0256 0.0302
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0208 0.0245
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0112 0.0256 0.0249
Trypanosoma brucei heat shock protein, putative 0.0074 0.0132 0.0292
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.0368 0.0472
Trypanosoma brucei hypothetical protein, conserved 0.0077 0.0141 0.0312
Schistosoma mansoni chromosome transmission fidelity factor 0.0053 0.0062 0.0073
Onchocerca volvulus 0.0049 0.0049 0.0044
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.011 0.0135
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Toxoplasma gondii ABC1 family protein 0.0077 0.0141 0.0803
Schistosoma mansoni septate junction protein 0.0112 0.0256 0.0325
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0044 0.0045
Echinococcus multilocularis roundabout 2 0.0112 0.0256 0.0302
Echinococcus granulosus neuroglian 0.0182 0.0486 0.0626
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0049 0.0049 0.0042
Trypanosoma brucei heat shock protein, putative 0.0074 0.0132 0.0292
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0124 0.0296 0.1924
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0178 0.0473 0.2799
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0174 0.2183
Echinococcus granulosus microtubule associated protein 2 0.2357 0.7668 1
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0062 0.0092 0.0112
Onchocerca volvulus 0.0049 0.0049 0.0044
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Loa Loa (eye worm) hypothetical protein 0.0077 0.0141 0.0134
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0178 0.0473 0.2799
Echinococcus multilocularis titin 0.005 0.005 0.0053
Loa Loa (eye worm) hypothetical protein 0.0053 0.0062 0.0056
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0074 0.0132 0.075
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0222 0.0281
Trichomonas vaginalis heat shock protein, putative 0.0074 0.0132 0.1634
Trypanosoma cruzi DNA topoisomerase II, putative 0.0074 0.0132 0.0292
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Trypanosoma brucei DNA topoisomerase ii 0.0074 0.0132 0.0292
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0028 0.0128
Brugia malayi Immunoglobulin I-set domain containing protein 0.0112 0.0256 0.0256
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0077 0.0141 0.0134
Leishmania major hypothetical protein, conserved 0.0053 0.0062 0.013
Brugia malayi Immunoglobulin I-set domain containing protein 0.0062 0.0092 0.0092
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Onchocerca volvulus Netrin receptor homolog 0.0049 0.0049 0.0044
Loa Loa (eye worm) hypothetical protein 0.0112 0.0256 0.0249
Plasmodium vivax endoplasmin, putative 0.0074 0.0132 0.2681
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0124 0.0296 0.5204
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0074 0.0132 0.0832
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0078 0.0935
Giardia lamblia Heat shock protein HSP 90-alpha 0.0074 0.0132 0.7333
Echinococcus multilocularis lachesin 0.0112 0.0256 0.0302
Mycobacterium tuberculosis Possible two component sensor kinase 0.0074 0.0132 0.0832
Echinococcus multilocularis heat shock protein 0.0074 0.0132 0.0152
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0053 0.0062 0.013
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0087
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0074 0.0132 0.225
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0078 0.0935
Schistosoma mansoni microtubule-associated protein tau 0.2357 0.7668 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0047 0.0054
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0063 0.0093 0.0114
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0053 0.0063 0.0068
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0141 0.0175
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0074 0.0132 0.0164
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0112 0.0256 0.0302
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0124 0.0296 0.6201
Loa Loa (eye worm) hypothetical protein 0.0074 0.0132 0.0125
Echinococcus multilocularis sterol regulatory element binding protein 0.018 0.0481 0.0576
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0007 0.0007
Echinococcus granulosus beta LACTamase domain containing family member 0.0077 0.0141 0.0175
Loa Loa (eye worm) hypothetical protein 0.0112 0.0256 0.0249
Echinococcus granulosus replication factor c subunit 1 0.0053 0.0062 0.0073
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0074 0.0132 0.0292
Onchocerca volvulus 0.0049 0.0049 0.0044
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0186
Loa Loa (eye worm) beta-lactamase 0.0077 0.0141 0.0134
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0063 0.0093 0.0106
Mycobacterium leprae Probable two-component sensor kinase 0.0074 0.0132 0.2681
Loa Loa (eye worm) hypothetical protein 0.0221 0.0615 0.0609
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0049 0.0049 0.0055
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2533 0.825 1
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.1337 0.43 1
Brugia malayi RNA recognition motif domain containing protein 0.0207 0.0571 0.0571
Onchocerca volvulus Peroxidasin homolog 0.0049 0.0049 0.0044
Brugia malayi heat shock protein 90 0.0074 0.0132 0.0132
Echinococcus granulosus down syndrome cell adhesion 0.0049 0.0049 0.0055
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0074 0.0132 0.225
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0112 0.0256 0.0302
Brugia malayi hypothetical protein 0.0112 0.0257 0.0257
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0007 0.0007
Loa Loa (eye worm) MBCTL1 0.0054 0.0065 0.0059
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0139 0.0345 0.2251
Echinococcus granulosus nibrin 0.0053 0.0062 0.0073
Entamoeba histolytica hypothetical protein 0.0112 0.0257 0.198
Onchocerca volvulus 0.0049 0.0049 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0141 0.0312
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0207 0.0571 0.0565
Schistosoma mansoni survival motor neuron protein 0.0103 0.0226 0.0286
Leishmania major heat shock protein 83-1 0.0074 0.0132 0.0292
Echinococcus multilocularis jumonji domain containing protein 0.0046 0.0037 0.0037
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0154 0.0396 0.0396
Schistosoma mansoni topbp1 0.0053 0.0062 0.0073
Echinococcus multilocularis lamin 0.0111 0.0252 0.0298
Loa Loa (eye worm) hypothetical protein 0.0049 0.0049 0.0042
Schistosoma mansoni hypothetical protein 0.0049 0.0049 0.0055
Schistosoma mansoni myosin-binding protein-related 0.0049 0.0049 0.0055
Echinococcus multilocularis beta LACTamase domain containing family member 0.0077 0.0141 0.0163
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0205 0.0563 1
Echinococcus multilocularis peptidase Clp (S14 family) 0.0117 0.0271 0.0321
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0063 0.0093 0.0106
Echinococcus multilocularis nibrin 0.0053 0.0062 0.0068
Trypanosoma cruzi Heat shock protein 83, putative 0.0074 0.0132 0.0292
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0467 0.1429 0.8528
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0028 0.0128
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0178 0.0473 1
Leishmania major heat shock protein 83-1 0.0074 0.0132 0.0292
Brugia malayi Calcitonin receptor-like protein seb-1 0.0154 0.0396 0.0396
Schistosoma mansoni endoplasmin 0.0074 0.0132 0.0163
Schistosoma mansoni titin 0.0049 0.0049 0.0055
Schistosoma mansoni basigin related 0.0063 0.0093 0.0113
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0078 0.0167
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.0368 0.0368
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0087 0.0174 0.039
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0542 0.1675 1
Echinococcus granulosus titin 0.0049 0.0049 0.0055
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0065 0.0072
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0074 0.0132 0.225
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0049 0.0049 0.0055
Mycobacterium tuberculosis Probable lipase LipE 0.0077 0.0141 0.0891
Loa Loa (eye worm) hypothetical protein 0.0053 0.0062 0.0056
Echinococcus granulosus mitogen activated protein kinase 3 0.0058 0.0078 0.0094
Loa Loa (eye worm) hypothetical protein 0.0109 0.0245 0.0239
Echinococcus granulosus titin 0.0049 0.0049 0.0055
Brugia malayi hypothetical protein 0.0504 0.1551 0.1551
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Brugia malayi Animal haem peroxidase family protein 0.0049 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0112 0.0256 0.0249
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0049 0.0049 0.0051
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0078 0.0935
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0117 0.0271 0.5667
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0063 0.0093 0.0106
Echinococcus granulosus Immunoglobulin 0.0063 0.0093 0.0114
Schistosoma mansoni aldehyde dehydrogenase 0.0139 0.0345 0.0442
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0062 0.0726
Schistosoma mansoni septate junction protein 0.0063 0.0093 0.0113
Brugia malayi CHE-14 protein 0.018 0.0481 0.0481
Schistosoma mansoni hypothetical protein 0.0105 0.0235 0.0298
Plasmodium falciparum heat shock protein 90 0.0074 0.0132 0.2681
Schistosoma mansoni tar DNA-binding protein 0.0207 0.0571 0.0736
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0205 0.0563 1
Onchocerca volvulus 0.0053 0.0062 0.0058
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0087 0.0174 0.0219
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0062 0.0726
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0063 0.0093 0.0113
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0208 0.0263
Echinococcus multilocularis roundabout 2 0.0244 0.0693 0.0833
Brugia malayi Myb-like DNA-binding domain containing protein 0.0049 0.0049 0.0049
Loa Loa (eye worm) TK/ROR protein kinase 0.0062 0.0092 0.0086
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0112 0.0256 0.0249
Brugia malayi Prion-like- 0.0049 0.0049 0.0049
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0049 0.0049
Trypanosoma brucei heat shock protein, putative 0.0074 0.0132 0.0292
Echinococcus granulosus lachesin 0.0112 0.0256 0.0325
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0205 0.0563 0.0726
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0049 0.0049 0.0042
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0074 0.0132 0.0832
Brugia malayi RNA binding protein 0.0207 0.0571 0.0571
Echinococcus granulosus twitchin 0.0182 0.0488 0.0629
Echinococcus granulosus nephrin 0.0049 0.0049 0.0055
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0074 0.0132 0.0292
Brugia malayi intermediate filament protein 0.0111 0.0252 0.0252
Echinococcus granulosus sterol regulatory element binding protein 0.018 0.0481 0.062
Loa Loa (eye worm) intermediate filament protein 0.0111 0.0252 0.0246
Loa Loa (eye worm) hypothetical protein 0.0053 0.0062 0.0056
Schistosoma mansoni cell adhesion molecule 0.0049 0.0049 0.0055
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0141 0.0175
Schistosoma mansoni nephrin related 0.0049 0.0049 0.0055
Brugia malayi Immunoglobulin I-set domain containing protein 0.0063 0.0093 0.0093
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0016 0.0075
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0058 0.0078 0.0429
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0074 0.0132 0.0152
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0178 0.0473 0.8392
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0062 0.013
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0141 0.175
Schistosoma mansoni hypothetical protein 0.0049 0.0049 0.0055
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0053 0.0062 0.1192
Loa Loa (eye worm) hypothetical protein 0.0178 0.0473 0.0467
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0111 0.0252 0.0246
Schistosoma mansoni aldehyde dehydrogenase 0.0139 0.0345 0.0442
Brugia malayi jmjC domain containing protein 0.0175 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.0112 0.0256 0.0249
Mycobacterium ulcerans two component regulator - sensor kinase 0.0074 0.0132 0.225
Schistosoma mansoni hypothetical protein 0.0063 0.0093 0.0113
Trichomonas vaginalis set domain proteins, putative 0.0268 0.0773 1
Echinococcus multilocularis transfer RNA-Phe 0.0049 0.0049 0.0051
Leishmania major heat shock protein 83-1 0.0074 0.0132 0.0292
Plasmodium vivax DNA topoisomerase II, putative 0.0074 0.0132 0.2681
Trypanosoma brucei Heat shock protein 83, putative 0.0074 0.0132 0.0292
Brugia malayi Prion-like- 0.0049 0.0049 0.0049
Trypanosoma brucei heat shock protein, putative 0.0074 0.0132 0.0292
Schistosoma mansoni DNA ligase IV 0.0053 0.0062 0.0073
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0078 0.0093
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0047 0.005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0208 0.0263
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0087 0.0174 0.0203
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0049 0.0049 0.0055
Brugia malayi hypothetical protein 0.0133 0.0324 0.0324
Mycobacterium ulcerans esterase/lipase LipP 0.0077 0.0141 0.2409
Brugia malayi Immunoglobulin I-set domain containing protein 0.0112 0.0256 0.0256
Brugia malayi Bromodomain containing protein 0.0036 0.0006 0.0006
Schistosoma mansoni titin 0.0049 0.0049 0.0055
Mycobacterium ulcerans aldehyde dehydrogenase 0.0139 0.0345 0.6089
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0047 0.0047
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0053 0.0062 0.1
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0205 0.0563 0.0563
Brugia malayi mbt repeat family protein 0.0048 0.0044 0.0044
Schistosoma mansoni transcription factor LCR-F1 0.0112 0.0257 0.0327
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0053 0.0062 0.0726
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.1337 0.43 0.5208
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0133 0.0324 0.0414
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0074 0.0132 0.0132
Leishmania major mitochondrial DNA topoisomerase II 0.0074 0.0132 0.0292
Brugia malayi hypothetical protein 0.0053 0.0062 0.0062
Echinococcus multilocularis microtubule associated protein 2 0.2357 0.7668 0.9294
Brugia malayi Immunoglobulin I-set domain containing protein 0.0063 0.0093 0.0093
Mycobacterium ulcerans aldehyde dehydrogenase 0.0139 0.0345 0.6089
Brugia malayi cytoplasmic intermediate filament protein 0.0059 0.0082 0.0082
Brugia malayi Immunoglobulin I-set domain containing protein 0.0112 0.0256 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0062 0.0726
Echinococcus granulosus defective proboscis extension response 0.0133 0.0324 0.0415
Loa Loa (eye worm) hypothetical protein 0.0093 0.0192 0.0186
Schistosoma mansoni hypothetical protein 0.0063 0.0093 0.0113
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0087

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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