Detailed information for compound 101751

Basic information

Technical information
  • TDR Targets ID: 101751
  • Name: N-[4-[2-[[(2S)-3-(6-aminopyridin-3-yl)oxy-2-h ydroxypropyl]amino]ethyl]phenyl]-4-propan-2-y lbenzenesulfonamide
  • MW: 484.611 | Formula: C25H32N4O4S
  • H donors: 4 H acceptors: 4 LogP: 3.03 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@H](COc1ccc(nc1)N)CNCCc1ccc(cc1)NS(=O)(=O)c1ccc(cc1)C(C)C
  • InChi: 1S/C25H32N4O4S/c1-18(2)20-5-10-24(11-6-20)34(31,32)29-21-7-3-19(4-8-21)13-14-27-15-22(30)17-33-23-9-12-25(26)28-16-23/h3-12,16,18,22,27,29-30H,13-15,17H2,1-2H3,(H2,26,28)/t22-/m0/s1
  • InChiKey: RSGITHTZWHPLBS-QFIPXVFZSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[4-[2-[[(2S)-3-[(6-amino-3-pyridyl)oxy]-2-hydroxy-propyl]amino]ethyl]phenyl]-4-isopropyl-benzenesulfonamide
  • N-[4-[2-[[(2S)-3-[(6-amino-3-pyridyl)oxy]-2-hydroxypropyl]amino]ethyl]phenyl]-4-isopropylbenzenesulfonamide
  • N-[4-[2-[[(2S)-3-(6-azanylpyridin-3-yl)oxy-2-hydroxy-propyl]amino]ethyl]phenyl]-4-propan-2-yl-benzenesulfonamide
  • N-[4-[2-[[(2S)-3-(6-aminopyridin-3-yl)oxy-2-hydroxy-propyl]amino]ethyl]phenyl]-4-propan-2-yl-benzenesulfonamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens adrenoceptor beta 2, surface Starlite/ChEMBL References
Homo sapiens adrenoceptor beta 3 Starlite/ChEMBL References
Homo sapiens adrenoceptor beta 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni neuropeptide f receptor 76f 0.002 0.0208 0.0306
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0355 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.1122 0.6565
Trypanosoma brucei DNA damage repair protein, putative 0.0013 0.0073 0.042
Schistosoma mansoni hypothetical protein 0.002 0.0208 0.0306
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.014 0.0812
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Brugia malayi orphan nuclear receptor NR2E1 0.0031 0.0385 0.0383
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0073 0.1122 0.1118
Loa Loa (eye worm) hypothetical protein 0.0031 0.0385 0.0381
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Loa Loa (eye worm) hypothetical protein 0.0026 0.0299 0.0295
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0009 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0581 0.0724
Onchocerca volvulus Cathepsin L homolog 0.0017 0.014 0.0655
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0449 0.0447
Loa Loa (eye worm) hypothetical protein 0.0032 0.0412 0.0409
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0208 0.0258
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0299 0.0295
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0208 0.0306
Leishmania major importin beta-1 subunit, putative 0.0023 0.0248 0.1417
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0175 0.4906
Echinococcus granulosus neuropeptide FF receptor 2 0.002 0.0208 0.0258
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0713 0.4172
Schistosoma mansoni growth hormone secretagogue receptor 0.002 0.0208 0.0306
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.056 0.3271
Brugia malayi neuropeptide F receptor 0.002 0.0208 0.0206
Echinococcus granulosus agrin 0.0022 0.0235 0.0293
Leishmania major cathepsin L-like protease 0.0017 0.014 0.0781
Echinococcus granulosus neuropeptide s receptor 0.002 0.0208 0.0258
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0713 0.4172
Schistosoma mansoni hypothetical protein 0.0343 0.5771 0.8547
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0009 0.0007 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0065 0.0979 0.0978
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0208 0.0258
Entamoeba histolytica hypothetical protein 0.0072 0.1099 0.6431
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Schistosoma mansoni agrin 0.0022 0.0235 0.0346
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0299 0.0298
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0581 0.3393
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.014 0.0812
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.002 0.0208 0.0306
Schistosoma mansoni neuropeptide receptor 0.002 0.0208 0.0306
Echinococcus granulosus Solute carrier organic anion transporter family 0.0032 0.0412 0.0514
Onchocerca volvulus Netrin receptor homolog 0.0014 0.01 0.0466
Schistosoma mansoni thyroid hormone receptor 0.019 0.3129 0.4634
Onchocerca volvulus 0.002 0.0208 0.0971
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0009 0.0007 0.0007
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.0449 0.0662
Loa Loa (eye worm) hypothetical protein 0.0207 0.3423 0.3421
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0208 0.0306
Loa Loa (eye worm) hypothetical protein 0.0026 0.0299 0.0295
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.056 0.3271
Brugia malayi Dopamine receptor protein 2 0.002 0.0208 0.0206
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.1122 0.1217
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1708 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.002 0.0208 0.0206
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0065 0.0979 0.0976
Entamoeba histolytica hypothetical protein 0.0072 0.1099 0.6431
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Schistosoma mansoni hypothetical protein 0.0125 0.2004 0.2967
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.1122 0.1217
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0944 0.5521
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Brugia malayi AKH receptor 0.002 0.0208 0.0206
Schistosoma mansoni alpha-1 adrenergic receptor 0.002 0.0208 0.0306
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0469 0.7953 1
Onchocerca volvulus Putative organic anion transporter 0.0032 0.0412 0.1928
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0355 0.312
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0034
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.014 0.0173
Brugia malayi polk-prov protein 0.0013 0.0073 0.0072
Loa Loa (eye worm) hypothetical protein 0.0022 0.0235 0.0232
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0031 0.0385 0.0568
Schistosoma mansoni adenoreceptor 0.002 0.0208 0.0306
Brugia malayi sodium-independent organic anion transporter family protein 0.0032 0.0412 0.0411
Echinococcus granulosus tar DNA binding protein 0.0062 0.0916 0.1144
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0064 0.0368
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0212 0.1877
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0916 0.1355
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0009 0.0007 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0944 0.5521
Echinococcus granulosus somatostatin receptor 0.002 0.0208 0.0258
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0208 0.0306
Onchocerca volvulus 0.0032 0.0412 0.1928
Brugia malayi 6-phosphofructokinase 0.0107 0.1708 0.1707
Loa Loa (eye worm) hypothetical protein 0.0472 0.7995 0.7995
Schistosoma mansoni hypothetical protein 0.0301 0.5042 0.7467
Onchocerca volvulus 0.002 0.0208 0.0971
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Loa Loa (eye worm) nuclear receptor NHR-67 0.0031 0.0385 0.0381
Echinococcus granulosus neuropeptide receptor 0.002 0.0208 0.0258
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0385 0.0383
Plasmodium vivax importin-beta 2, putative 0.0028 0.034 0.3023
Loa Loa (eye worm) beta-lactamase 0.0073 0.1122 0.1118
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0042 0.0581 0.3371
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0009 0.0007 0.0007
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.1122 0.1217
Echinococcus multilocularis G-protein coupled receptor, putative 0.002 0.0208 0.0258
Entamoeba histolytica hypothetical protein 0.0023 0.0248 0.1446
Loa Loa (eye worm) hypothetical protein 0.0032 0.0412 0.0409
Brugia malayi hypothetical protein 0.0072 0.1099 0.1098
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Echinococcus granulosus 7tm_1 domain containing protein 0.002 0.0208 0.0258
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0183 0.3014 0.3011
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0581 0.3393
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0944 0.5521
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.056 0.0558
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.0007
Echinococcus multilocularis cysteine protease 0.0017 0.014 0.0173
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.014 0.0812
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Echinococcus multilocularis survival motor neuron protein 1 0.0472 0.7995 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.014 0.0173
Brugia malayi hypothetical protein 0.002 0.0208 0.0206
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.014 0.3922
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0175 0.1016
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0065 0.0979 0.4579
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.1122 0.6565
Schistosoma mansoni importin beta-1 0.0028 0.034 0.0502
Schistosoma mansoni peptidase 0.0009 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0385 0.0381
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0355 0.2072
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Brugia malayi Protein kinase domain containing protein 0.0015 0.0107 0.0106
Echinococcus multilocularis sex peptide receptor 0.002 0.0208 0.0258
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Brugia malayi beta-lactamase family protein 0.0073 0.1122 0.1121
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0208 0.0258
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0047 0.0057
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0944 0.5521
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0034
Onchocerca volvulus 0.0032 0.0412 0.1928
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0944 0.5521
Brugia malayi Serotonin receptor 0.002 0.0208 0.0206
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Schistosoma mansoni amine GPCR 0.002 0.0208 0.0306
Onchocerca volvulus 0.002 0.0208 0.0971
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0009 0.0007 0.0009
Loa Loa (eye worm) steroid hormone receptor 0.0065 0.0979 0.0976
Schistosoma mansoni peroxidasin 0.0026 0.0299 0.0441
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0299 0.0298
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0284 0.1653
Trypanosoma brucei protein kinase, putative 0.005 0.0713 0.4172
Loa Loa (eye worm) hypothetical protein 0.0031 0.0385 0.0381
Echinococcus granulosus cpg binding protein 0.003 0.0366 0.0456
Brugia malayi conserved hypotetical protein 0.0031 0.0385 0.0383
Schistosoma mansoni hypothetical protein 0.002 0.0208 0.0306
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Mycobacterium ulcerans hypothetical protein 0.0013 0.0073 0.0054
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0208 0.0258
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0065 0.0979 0.0976
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.014 0.0812
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0009 0.0007 0.0006
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0009 0.0007 0.0164
Schistosoma mansoni DNA polymerase eta 0.0041 0.056 0.0827
Loa Loa (eye worm) hypothetical protein 0.0011 0.0046 0.0042
Plasmodium falciparum ubiquitin specific protease, putative 0.0009 0.0007 0.0164
Echinococcus multilocularis GPCR, family 2 0.0016 0.0131 0.0162
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.014 0.3922
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0208 0.0258
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0581 0.3393
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0208 0.0258
Echinococcus granulosus survival motor neuron protein 1 0.0472 0.7995 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Schistosoma mansoni nuclear receptor 0.0031 0.0385 0.0568
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0065 0.0979 0.1223
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.014 0.0812
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0031 0.0385 0.0381
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Brugia malayi Cathepsin L-like precursor 0.0017 0.014 0.0139
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0065 0.0979 0.1223
Schistosoma mansoni hypothetical protein 0.0096 0.1515 0.2242
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.014 0.0812
Onchocerca volvulus Cathepsin F homolog 0.0017 0.014 0.0655
Schistosoma mansoni nuclear hormone receptor 0.0065 0.0979 0.1449
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0208 0.0258
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Onchocerca volvulus 0.0017 0.014 0.0655
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0006
Echinococcus multilocularis g-protein coupled receptor 0.002 0.0208 0.0258
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.1515 0.1513
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0009 0.0007 0.0052
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0208 0.0258
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trypanosoma brucei hypothetical protein, conserved 0.0013 0.0073 0.042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0944 0.5521
Echinococcus granulosus serotonin receptor 0.002 0.0208 0.0258
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.1122 0.1121
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0022 0.0235 0.2046
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus granulosus jun protein 0.0169 0.2763 0.3455
Trichomonas vaginalis ubiquitin specific protease, putative 0.0009 0.0007 0.0034
Echinococcus multilocularis cysteine protease 0.0017 0.014 0.0173
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.014 0.3922
Loa Loa (eye worm) STAT protein 0.0337 0.5678 0.5677
Onchocerca volvulus 0.0017 0.014 0.0655
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0009 0.0007 0.0007
Onchocerca volvulus 0.002 0.0208 0.0971
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0212 0.0208
Leishmania major ATP-dependent phosphofructokinase 0.0107 0.1708 1
Echinococcus granulosus Ankyrin 0.0014 0.0102 0.0125
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0065 0.0979 0.1223
Brugia malayi hypothetical protein 0.0034 0.0449 0.0447
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0003
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0131 0.0127
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0183 0.3014 0.3768
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.056 0.3271
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0065 0.0979 0.1223
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Schistosoma mansoni ran 0.0021 0.0212 0.0312
Schistosoma mansoni calpain-7 (C02 family) 0.0009 0.0007 0.0009
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.034 0.1984
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0034
Brugia malayi larval opioid receptor 0.002 0.0208 0.0206
Brugia malayi neuropeptide F receptor 0.002 0.0208 0.0206
Schistosoma mansoni jun-related protein 0.0137 0.2218 0.3284
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.01 0.0146
Loa Loa (eye worm) hypothetical protein 0.0031 0.0385 0.0381
Echinococcus multilocularis ubiquitin specific protease 41 0.0042 0.0581 0.0724
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0034
Trypanosoma brucei chrX additional, unordered contigs 0.0013 0.0073 0.042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0248 0.1446
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0385 0.048
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0881 0.1304
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.056 0.3271
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0208 0.0306
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0065 0.0979 0.1223
Echinococcus multilocularis dnaJ subfamily B 0.04 0.6751 0.8444
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0208 0.0258
Echinococcus granulosus sex peptide receptor 0.002 0.0208 0.0258
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0022 0.0235 0.2046
Onchocerca volvulus 0.0073 0.1122 0.5246
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0916 0.1355
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0385 0.048
Echinococcus multilocularis dro:myosuppressin receptor 0.002 0.0208 0.0258
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0172 0.2825 0.3532
Loa Loa (eye worm) cysteine protease 0.0017 0.014 0.0136
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0169 0.2763 0.3455
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0125 0.2004 0.2505
Schistosoma mansoni cpg binding protein 0.003 0.0366 0.054
Echinococcus granulosus GPCR family 2 0.0016 0.0131 0.0162
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0944 0.5521
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0065 0.0979 0.1223
Schistosoma mansoni steroid hormone receptor ad4bp 0.0065 0.0979 0.1449
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Brugia malayi putative neuropeptide receptor NPR1 0.002 0.0208 0.0206
Loa Loa (eye worm) hypothetical protein 0.0034 0.0449 0.0445
Schistosoma mansoni peroxidasin 0.0026 0.0299 0.0441
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.01 0.0123
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.056 0.3271
Trypanosoma cruzi DNA polymerase eta, putative 0.0041 0.056 0.3271
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0034
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0385 0.048
Brugia malayi nuclear hormone receptor family member odr-7 0.0031 0.0385 0.0383
Echinococcus multilocularis g protein coupled receptor 0.002 0.0208 0.0258
Trypanosoma cruzi DNA polymerase eta, putative 0.0013 0.0073 0.042
Leishmania major cathepsin L-like protease 0.0017 0.014 0.0781
Brugia malayi Cathepsin L-like precursor 0.0011 0.0046 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Onchocerca volvulus 0.002 0.0208 0.0971
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0006
Brugia malayi GnHR receptor homolog 0.002 0.0208 0.0206
Echinococcus granulosus ubiquitin specific peptidase c family 0.0009 0.0007 0.0007
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0208 0.0306
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0355 0.2072
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0065 0.0979 0.0978
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0065 0.0979 0.0978
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0009 0.0007 0.0009
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0916 0.0912
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.014 0.0136
Echinococcus multilocularis neuropeptide FF receptor 2 0.002 0.0208 0.0258
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0009 0.0007 0.0007
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0713 0.0891
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.1122 0.166
Trichomonas vaginalis ubiquitin specific protease, putative 0.0009 0.0007 0.0034
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0163 0.2663 0.3329
Echinococcus granulosus FTZ F1 alpha 0.0065 0.0979 0.1223
Trypanosoma cruzi MFS transporter, putative 0.0032 0.0412 0.2408
Loa Loa (eye worm) hypothetical protein 0.0014 0.0102 0.0098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0046 0.0259
Schistosoma mansoni hypothetical protein 0.0016 0.0131 0.0192
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Echinococcus granulosus peroxidasin 0.0026 0.0299 0.0372
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.056 0.0495
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Leishmania major cathepsin L-like protease 0.0063 0.0944 0.5506
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0385 0.0568
Schistosoma mansoni hypothetical protein 0.0014 0.01 0.0146
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0009 0.0007 0.0007
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0009 0.0007 0.0007
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0034
Onchocerca volvulus Putative organic anion transporter 0.0032 0.0412 0.1928
Onchocerca volvulus 0.002 0.0208 0.0971
Brugia malayi tailless protein 0.0031 0.0385 0.0383
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.014 0.0205
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0064 0.0368
Loa Loa (eye worm) hypothetical protein 0.0026 0.0299 0.0295
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Echinococcus granulosus death domain containing protein 0.0014 0.01 0.0123
Loa Loa (eye worm) hypothetical protein 0.0032 0.0412 0.0409
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.002 0.0208 0.0206
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.002 0.0208 0.0258
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Onchocerca volvulus 0.0017 0.014 0.0655
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.002 0.0208 0.0258
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.1122 0.6565
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.002 0.0208 0.0258
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.1708 0.1705
Onchocerca volvulus Protein ultraspiracle homolog 0.0065 0.0979 0.4579
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0073 0.1122 0.1118
Loa Loa (eye worm) hypothetical protein 0.0035 0.0453 0.0449
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Brugia malayi hypothetical protein 0.0009 0.0007 0.0006
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.1708 0.2528
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0208 0.0204
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0183 0.3014 0.4463
Mycobacterium ulcerans beta-lactamase 0.0073 0.1122 0.6434
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0065 0.0979 0.1223
Onchocerca volvulus 0.0026 0.0299 0.1398
Brugia malayi SPARC precursor 0.0022 0.0235 0.0234
Brugia malayi Blistered cuticle protein 3 0.0026 0.0299 0.0298
Loa Loa (eye worm) hypothetical protein 0.0022 0.0235 0.0232
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0581 0.0724
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0581 0.0724
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0208 0.0258
Leishmania major cathepsin L-like protease 0.0017 0.014 0.0781
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.073 0.0726
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.002 0.0208 0.0204
Loa Loa (eye worm) hypothetical protein 0.0031 0.0385 0.0381
Toxoplasma gondii transporter, major facilitator family protein 0.0032 0.0412 0.3635
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0026 0.0299 0.0295
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0849 0.4967
Mycobacterium ulcerans 6-phosphofructokinase 0.0107 0.1708 1
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.1708 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Echinococcus multilocularis tachykinin peptides receptor 99D 0.002 0.0208 0.0258
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0009 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0009 0.0007 0.0009
Onchocerca volvulus 0.002 0.0208 0.0971
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0248 0.4136 0.4134
Schistosoma mansoni neuropeptide receptor 0.002 0.0208 0.0306
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0034 0.0449 0.0559
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.1122 0.1402
Brugia malayi gonadotropin-releasing hormone receptor 2 0.002 0.0208 0.0206
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0003
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0385 0.18
Brugia malayi steroid hormone receptor 0.0065 0.0979 0.0978
Entamoeba histolytica hypothetical protein 0.0009 0.0007 0.0034
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0064 0.006
Echinococcus granulosus neuropeptide receptor A26 0.002 0.0208 0.0258
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.002 0.0208 0.0306
Onchocerca volvulus 0.0011 0.0046 0.0213
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0355 0.4924
Onchocerca volvulus 0.0017 0.014 0.0655
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0713 0.0891
Onchocerca volvulus 0.0009 0.0007 0.0034
Brugia malayi RNA, U transporter 1 0.008 0.1236 0.1235
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0208 0.0306
Brugia malayi hypothetical protein 0.0026 0.0299 0.0298
Onchocerca volvulus 0.002 0.0208 0.0971
Schistosoma mansoni myosin xvIII 0.002 0.0208 0.0306
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0772 0.6858
Brugia malayi hypothetical protein 0.002 0.0208 0.0206
Brugia malayi ecdysteroid receptor 0.0065 0.0979 0.0978
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0031 0.0385 0.0381
Onchocerca volvulus Dual oxidase homolog 0.0026 0.0299 0.1398
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0034
Echinococcus multilocularis neuropeptide receptor A26 0.002 0.0208 0.0258
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0022 0.0235 0.2046
Brugia malayi putative neuropeptide receptor 0.002 0.0208 0.0206
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0032 0.0412 0.0409
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0208 0.0258
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Brugia malayi Serotonin receptor 0.002 0.0208 0.0206
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0006
Echinococcus granulosus dna polymerase kappa 0.0041 0.056 0.0698
Brugia malayi Dopamine receptor protein 1 0.002 0.0208 0.0206
Echinococcus granulosus G protein coupled receptor 139 0.002 0.0208 0.0258
Schistosoma mansoni nuclear receptor nhr-48 0.0031 0.0385 0.0568
Brugia malayi RNA binding protein 0.0062 0.0916 0.0915
Loa Loa (eye worm) hypothetical protein 0.0026 0.0299 0.0295
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0208 0.0306
Leishmania major DNA polymerase kappa, putative 0.0013 0.0073 0.0387
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus multilocularis thyroid hormone receptor alpha 0.019 0.3129 0.3913
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0713 0.6335
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0013 0.0073 0.0591
Loa Loa (eye worm) hypothetical protein 0.0034 0.0449 0.0445
Brugia malayi 6-phosphofructokinase 0.0107 0.1708 0.1707
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.056 0.3271
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.014 0.0139
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Onchocerca volvulus Peroxidase homolog 0.0026 0.0299 0.1398
Brugia malayi hypothetical protein 0.0132 0.2139 0.2137
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1708 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.056 0.3014
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0713 0.4172
Loa Loa (eye worm) hypothetical protein 0.0031 0.0385 0.0381
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.01 0.0098
Mycobacterium tuberculosis Conserved protein 0.0073 0.1122 0.1217
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0248 0.1446
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.056 0.3271
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0065 0.0979 0.0978
Echinococcus multilocularis snurportin 1 0.0301 0.5042 0.6305
Brugia malayi hypothetical protein 0.002 0.0208 0.0206
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus multilocularis peroxidasin 0.0026 0.0299 0.0372
Echinococcus multilocularis fmrfamide receptor 0.002 0.0208 0.0258
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.014 0.0812
Brugia malayi G-protein coupled receptor 0.002 0.0208 0.0206
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0006
Trypanosoma brucei unspecified product 0.0028 0.0341 0.1988
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0944 0.5521
Schistosoma mansoni amine GPCR 0.002 0.0208 0.0306
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0355 0.312
Brugia malayi hypothetical protein 0.002 0.0208 0.0206
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.014 0.0173
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Schistosoma mansoni hypothetical protein 0.0011 0.0047 0.0067
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0284 0.1653
Echinococcus granulosus neuropeptide receptor 0.002 0.0208 0.0258
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Schistosoma mansoni calpain-7 (C02 family) 0.0009 0.0007 0.0009
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0022 0.0235 0.0232
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Entamoeba histolytica Ran family GTPase 0.0021 0.0212 0.1233
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0208 0.0258
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0208 0.0258
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0009 0.0007 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0065 0.0979 0.0978
Schistosoma mansoni follistatin 0.0022 0.0235 0.0346
Schistosoma mansoni hypothetical protein 0.0072 0.1099 0.1626
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0073 0.042
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0009 0.0007 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1708 1
Onchocerca volvulus 0.0096 0.1515 0.7083
Trichomonas vaginalis ubiquitin specific protease, putative 0.0009 0.0007 0.0034
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0175 0.1016
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0065 0.0979 0.1449
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0031 0.0385 0.0383
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus multilocularis G protein coupled receptor 139 0.002 0.0208 0.0258
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0301 0.5042 0.504
Brugia malayi Steroid receptor seven-up type 2 0.0065 0.0979 0.0978
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.014 0.0812
Schistosoma mansoni hypothetical protein 0.0016 0.0131 0.0192
Echinococcus multilocularis geminin 0.0343 0.5771 0.7217
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0299 0.1398
Echinococcus granulosus allatostatin A receptor 0.002 0.0208 0.0258
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0065 0.0979 0.0978
Leishmania major cytochrome p450-like protein 0.0012 0.0064 0.0335
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0006
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0032 0.0412 0.0514
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0052
Echinococcus granulosus geminin 0.0343 0.5771 0.7217
Schistosoma mansoni thyroid hormone receptor 0.019 0.3129 0.4634
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0009 0.0007 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.014 0.0812
Brugia malayi hypothetical protein 0.002 0.0208 0.0206
Brugia malayi nuclear receptor NHR-88 0.0031 0.0385 0.0383
Loa Loa (eye worm) hypothetical protein 0.0028 0.034 0.0336
Loa Loa (eye worm) hypothetical protein 0.0164 0.2684 0.2681
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.014 0.0173
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.1099 0.1373
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0713 1
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0032 0.0412 0.0514
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0065 0.0979 0.0978
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.002 0.0208 0.0258
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0341 0.1988
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0009 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0073 0.1122 0.1118
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0009 0.0007 0.0009
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0713 0.4172
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0065 0.0979 0.1223
Brugia malayi Cathepsin L-like precursor 0.0017 0.014 0.0139
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0009 0.0007 0.0009
Echinococcus multilocularis g protein coupled receptor 0.002 0.0208 0.0258
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0009 0.0007 0.0007
Onchocerca volvulus Neuropeptide F receptor homolog 0.002 0.0208 0.0971
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0009 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Schistosoma mansoni nuclear receptor 0.0031 0.0385 0.0568
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0212 0.1233
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.002 0.0208 0.0258
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0009 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0031 0.0385 0.0381
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0065 0.0979 0.0976
Brugia malayi hypothetical protein 0.002 0.0208 0.0206
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0944 0.5521
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0034
Leishmania major cathepsin L-like protease 0.0063 0.0944 0.5506
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.056 0.3271
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0164
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0131 0.013
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.002 0.0208 0.0258
Onchocerca volvulus 0.0032 0.0412 0.1928
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0175 0.0986
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0212 0.2897
Onchocerca volvulus 0.0017 0.014 0.0655
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus granulosus cathepsin l1 0.0011 0.0046 0.0055
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0208 0.0258
Loa Loa (eye worm) agrin synaptic family protein 0.0022 0.0235 0.0232
Echinococcus granulosus alpha 1A adrenergic receptor 0.002 0.0208 0.0258
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0299 0.1398
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0009 0.0007 0.0003
Loa Loa (eye worm) hypothetical protein 0.0065 0.0979 0.0976
Schistosoma mansoni hypothetical protein 0.0343 0.5771 0.8547
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0022 0.0235 0.0234
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0022 0.0235 0.2046
Onchocerca volvulus 0.002 0.0208 0.0971
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0944 0.5521
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0009 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.056 0.3271
Brugia malayi nuclear receptor RXR 0.0031 0.0385 0.0383
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.0299 0.1398
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0009 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0338 0.0335
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0009 0.0007 0.0007
Loa Loa (eye worm) phosphofructokinase 0.0107 0.1708 0.1705
Echinococcus granulosus peptide allatostatin:somatostatin 0.002 0.0208 0.0258
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0009 0.0007 0.0034
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0355 0.2072
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0003
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0355 0.5
Echinococcus granulosus hypothetical protein 0.002 0.0208 0.0258
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0208 0.0258
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.056 0.3271
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0009 0.0007 0.0009
Trypanosoma cruzi DNA damage repair protein, putative 0.0013 0.0073 0.042
Loa Loa (eye worm) hypothetical protein 0.0588 1 1
Onchocerca volvulus 0.002 0.0208 0.0971
Onchocerca volvulus 0.0031 0.0385 0.18
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.1112 0.1389
Loa Loa (eye worm) hypothetical protein 0.0073 0.1122 0.1118
Plasmodium vivax ubiquitin specific protease, putative 0.0009 0.0007 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.056 0.3271
Schistosoma mansoni opsin-like receptor 0.002 0.0208 0.0306
Loa Loa (eye worm) hypothetical protein 0.0065 0.0979 0.0976
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0009 0.0007 0.0009
Leishmania major hypothetical protein, conserved 0.0025 0.0284 0.1624
Echinococcus multilocularis follistatin 0.0022 0.0235 0.0293
Loa Loa (eye worm) hypothetical protein 0.0034 0.0449 0.0445
Echinococcus granulosus tachykinin peptides receptor 99D 0.002 0.0208 0.0258
Brugia malayi Cytochrome P450 family protein 0.0012 0.0064 0.0063
Mycobacterium tuberculosis Conserved protein 0.0073 0.1122 0.1217
Schistosoma mansoni retinoic acid receptor RXR 0.0163 0.2663 0.3943
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0212 0.0263
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0102 0.0149
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0341 0.1988
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0355 0.2072
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0175 0.1016
Loa Loa (eye worm) hypothetical protein 0.0032 0.0412 0.0409
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0208 0.0258
Echinococcus multilocularis serotonin receptor 0.002 0.0208 0.0258
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0009 0.0007 0.0007
Plasmodium vivax DNA repair protein REV1, putative 0.0013 0.0073 0.0639
Echinococcus granulosus follistatin 0.0022 0.0235 0.0293
Brugia malayi nuclear receptor NHR-67 0.0031 0.0385 0.0383
Onchocerca volvulus 0.0026 0.0299 0.1398
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0003
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.002 0.0208 0.0204
Brugia malayi hypothetical protein 0.0025 0.0284 0.0282
Loa Loa (eye worm) hypothetical protein 0.0073 0.1122 0.1118
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Leishmania major cathepsin L-like protease 0.0017 0.014 0.0781
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0073 0.042
Schistosoma mansoni ran 0.0021 0.0212 0.0312
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.014 0.0205
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0009 0.0007 0.0009
Trypanosoma brucei cytochrome P450, putative 0.0012 0.0064 0.0368
Loa Loa (eye worm) hypothetical protein 0.0032 0.0412 0.0409
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0042 0.0581 0.8118
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0208 0.0258
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus granulosus g protein coupled receptor 0.002 0.0208 0.0258
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0042 0.0581 0.0579
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.1122 0.6565
Onchocerca volvulus 0.002 0.0208 0.0971
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0944 0.5521
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0009 0.0007 0.0034
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0169 0.2763 0.3455
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.002 0.0208 0.0206
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0208 0.0258
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.1122 0.6565
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.1099 0.1373
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.014 0.0812
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0052
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.056 0.3271
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.014 0.0173
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0009 0.0007 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0065 0.0979 0.0978
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0916 0.1144
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Entamoeba histolytica hypothetical protein 0.0072 0.1099 0.6431
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0009 0.0007 0.0007
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0299 0.0295
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0034
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0175 0.0173
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.002 0.0208 0.0306
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0004 0.0003
Onchocerca volvulus Cathepsin L homolog 0.0017 0.014 0.0655
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0065 0.0979 0.0978
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0034
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1708 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0175 0.0673
Loa Loa (eye worm) hypothetical protein 0.0031 0.0385 0.0381
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0208 0.0258
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0009 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.04 0.6751 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0284 0.7979
Leishmania major GTP-binding protein, putative 0.0021 0.0212 0.1203
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.002 0.0208 0.0258
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.002 0.0208 0.0306
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.1099 0.1626
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.1122 0.1217
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0009 0.0007 0.0009
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.014 0.0812
Toxoplasma gondii exonuclease III APE 0.0019 0.0175 0.1504
Loa Loa (eye worm) hypothetical protein 0.0011 0.0046 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Brugia malayi hypothetical protein 0.0016 0.0131 0.013
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.071 0.4155
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0006
Echinococcus granulosus nuclear receptor nhr 48 0.0031 0.0385 0.048
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0131 0.0162
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0208 0.0204
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0125 0.2004 0.2505
Echinococcus granulosus dro:myosuppressin receptor 0.002 0.0208 0.0258
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0034 0.0449 0.0445
Schistosoma mansoni opsin-like receptor 0.002 0.0208 0.0306
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Schistosoma mansoni hypothetical protein 0.002 0.0208 0.0306
Brugia malayi RE15519p 0.002 0.0208 0.0206
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0212 0.021
Schistosoma mansoni amine GPCR 0.002 0.0208 0.0306
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0713 0.071
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0175 0.0171
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0031 0.0385 0.048
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1708 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0299 0.0295
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0046 0.0259
Schistosoma mansoni terminal deoxycytidyl transferase 0.0041 0.056 0.0827
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0175 0.0217
Schistosoma mansoni hypothetical protein 0.0137 0.2218 0.3284
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Brugia malayi Importin beta-1 subunit 0.0028 0.034 0.0339
Schistosoma mansoni ap endonuclease 0.0019 0.0175 0.0257
Onchocerca volvulus 0.002 0.0208 0.0971
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0208 0.0306
Brugia malayi Dopamine receptor 0.002 0.0208 0.0206
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0031 0.0385 0.048
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0047 0.0057
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0208 0.0258
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0299 0.0295
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Onchocerca volvulus 0.0032 0.0412 0.1928
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0041 0.056 0.0698
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0128 0.2068 0.2586
Loa Loa (eye worm) hypothetical protein 0.0026 0.0299 0.0295
Echinococcus granulosus ecdysone induced protein 78C 0.0065 0.0979 0.1223
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.0299 0.0295
Echinococcus granulosus thyroid hormone receptor alpha 0.0031 0.0385 0.048
Entamoeba histolytica cysteine protease, putative 0.0017 0.014 0.0812
Brugia malayi beta-lactamase 0.0073 0.1122 0.1121
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0065 0.0979 0.0978
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.014 0.0812
Loa Loa (eye worm) RNA binding protein 0.0062 0.0916 0.0912
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0009 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Trypanosoma brucei unspecified product 0.0028 0.0341 0.1988
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0107 0.1708 0.1971
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0916 0.1355
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0009 0.0007 0.0052
Onchocerca volvulus 0.0022 0.0235 0.11
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0107 0.1708 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0065 0.0979 0.1223
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0183 0.3014 0.4463
Plasmodium vivax vivapain-2 0.0017 0.014 0.1237
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0284 0.1653
Trypanosoma brucei DNA polymerase eta, putative 0.0041 0.056 0.3271
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0355 0.5
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Brugia malayi Cathepsin L-like precursor 0.0017 0.014 0.0139
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus granulosus thyrotropin releasing hormone receptor 0.002 0.0208 0.0258
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.002 0.0208 0.0204
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0208 0.0258
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Brugia malayi Uncoordinated protein 44 0.0014 0.01 0.0098
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0022 0.0235 0.0234
Echinococcus multilocularis FTZ F1 alpha 0.0065 0.0979 0.1223
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Brugia malayi cathepsin L-like precursor 0.0011 0.0046 0.0044
Echinococcus multilocularis dna polymerase kappa 0.0041 0.056 0.0698
Onchocerca volvulus 0.002 0.0208 0.0971
Loa Loa (eye worm) hypothetical protein 0.0032 0.0412 0.0409
Brugia malayi MAP kinase sur-1 0.005 0.0713 0.0712
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.1122 0.1217
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0131 0.013
Schistosoma mansoni hypothetical protein 0.0009 0.0007 0.0009
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0065 0.0979 0.0976
Echinococcus multilocularis importin subunit beta 1 0.0028 0.034 0.0424
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.056 0.3271
Loa Loa (eye worm) hypothetical protein 0.0026 0.0299 0.0295
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Onchocerca volvulus 0.002 0.0208 0.0971
Brugia malayi Cathepsin L-like precursor 0.0017 0.014 0.0139
Onchocerca volvulus Putative organic anion transporter 0.0032 0.0412 0.1928
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0355 0.3155
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Schistosoma mansoni neuropeptide receptor 0.002 0.0208 0.0306
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0355 0.3155
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0713 0.4172
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0009 0.0007 0.0052
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.056 0.3271
Schistosoma mansoni netrin receptor unc5 0.0014 0.01 0.0146
Trypanosoma cruzi DNA damage repair protein, putative 0.0013 0.0073 0.042
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0065 0.0979 0.1223
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0208 0.0258
Loa Loa (eye worm) hypothetical protein 0.0065 0.0979 0.0976
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0208 0.0258
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0175 0.1016
Loa Loa (eye worm) hypothetical protein 0.0065 0.0979 0.0976
Schistosoma mansoni histamine h1 receptor 0.002 0.0208 0.0306
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0065 0.0979 0.1223
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0208 0.0258
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.056 0.3014
Plasmodium vivax hypothetical protein, conserved 0.0073 0.1122 1
Echinococcus granulosus dnaJ subfamily B 0.04 0.6751 0.8444
Leishmania major cathepsin L-like protease 0.0017 0.014 0.0781
Echinococcus multilocularis expressed protein 0.0009 0.0007 0.0007
Echinococcus granulosus orexin receptor type 2 0.002 0.0208 0.0258
Loa Loa (eye worm) hypothetical protein 0.0026 0.0299 0.0295
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0355 0.2072
Brugia malayi hypothetical protein 0.0032 0.0412 0.0411
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.014 0.0812
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.056 0.3271
Onchocerca volvulus 0.0032 0.0412 0.1928
Brugia malayi sulfakinin receptor protein 0.002 0.0208 0.0206
Loa Loa (eye worm) hypothetical protein 0.0016 0.0131 0.0127
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0009 0.0007 0.0007
Schistosoma mansoni neuropeptide receptor 0.002 0.0208 0.0306
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0022 0.0235 0.0232
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0016 0.0131 0.0192
Schistosoma mansoni peptide (allatostatin)-like receptor 0.002 0.0208 0.0306
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0009 0.0007 0.0009
Loa Loa (eye worm) fibroinase 0.0017 0.014 0.0136
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0355 0.312
Brugia malayi ORL1-like opioid receptor 0.002 0.0208 0.0206
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.01 0.0096
Loa Loa (eye worm) hypothetical protein 0.0065 0.0979 0.0976
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0065 0.0979 0.0978
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0713 0.0891
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0004 0.0003
Loa Loa (eye worm) melatonin receptor type 1A 0.002 0.0208 0.0204
Echinococcus multilocularis serotonin receptor 0.002 0.0208 0.0258
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0208 0.0258
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0385 0.18
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.014 0.0812
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0009 0.0007 0.0009
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0009 0.0007 0.0007
Onchocerca volvulus 0.0026 0.0299 0.1398
Toxoplasma gondii ABC1 family protein 0.0073 0.1122 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.002 0.0208 0.0306
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.002 0.0208 0.0204
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0006
Schistosoma mansoni coup transcription factor 0.0065 0.0979 0.1449
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0212 0.1233
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0073 0.042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Schistosoma mansoni RAR-like nuclear receptor 0.0065 0.0979 0.1449
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0355 0.2072
Echinococcus multilocularis biogenic amine (5HT) receptor 0.002 0.0208 0.0258
Brugia malayi hypothetical protein 0.002 0.0208 0.0206
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0007 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0034
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.1122 0.6565
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0022 0.0235 0.0234
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0212 0.595
Loa Loa (eye worm) ctsf protein 0.0017 0.014 0.0136
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0284 0.2479
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0065 0.0979 0.0978
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Loa Loa (eye worm) DR-78 0.0031 0.0385 0.0381
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0175 0.5
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0175 0.1016
Echinococcus granulosus 6 phosphofructokinase 0.0107 0.1708 0.2135
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.014 0.0812
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0299 0.0295
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0341 0.1988
Brugia malayi Cytochrome P450 family protein 0.0012 0.0064 0.0063
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0208 0.0258
Schistosoma mansoni hypothetical protein 0.002 0.0208 0.0306
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.002 0.0208 0.0306
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.01 0.0123
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0208 0.0306
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0713 0.0891
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0208 0.0306
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0208 0.0258
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0065 0.0979 0.1449
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.1122 0.6565
Loa Loa (eye worm) hypothetical protein 0.0031 0.0385 0.0381
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0065 0.0979 0.1449
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Toxoplasma gondii protease inhibitor PI2 0.0022 0.0235 0.2046
Loa Loa (eye worm) hypothetical protein 0.0025 0.0284 0.028
Schistosoma mansoni hypothetical protein 0.0016 0.0131 0.0192
Echinococcus granulosus netrin receptor unc 5 0.0014 0.01 0.0123
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0042 0.0581 0.0858
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0003
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Plasmodium vivax vivapain-2 0.0017 0.014 0.1237
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.014 0.0812
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0713 0.4172
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0009 0.0007 0.0009
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Onchocerca volvulus 0.002 0.0208 0.0971
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0944 0.5521
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0042 0.0581 0.0858
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.014 0.0812
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0013 0.0073 0.0591
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0299 0.0298
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0041 0.056 0.0827
Echinococcus multilocularis allatostatin A receptor 0.002 0.0208 0.0258
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0034 0.0449 0.0559
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0183 0.3014 0.3013
Brugia malayi Cathepsin L-like precursor 0.0017 0.014 0.0139
Echinococcus granulosus g protein coupled receptor 0.002 0.0208 0.0258
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Brugia malayi hypothetical protein 0.002 0.0208 0.0206
Echinococcus multilocularis 6 phosphofructokinase 0.0107 0.1708 0.2135
Plasmodium falciparum ubiquitin specific protease, putative 0.0009 0.0007 0.0164
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0009 0.0007 0.0164
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Loa Loa (eye worm) hypothetical protein 0.0014 0.01 0.0096
Schistosoma mansoni amine GPCR 0.002 0.0208 0.0306
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0208 0.0306
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0581 0.3393
Echinococcus multilocularis expressed protein 0.0022 0.0235 0.0293
Brugia malayi hypothetical protein 0.002 0.0208 0.0206
Loa Loa (eye worm) hypothetical protein 0.0017 0.014 0.0136
Schistosoma mansoni cpg binding protein 0.0028 0.0338 0.0499
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.056 0.3271
Brugia malayi hypothetical protein 0.0031 0.0385 0.0383
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0385 0.0568
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0212 0.1233
Trypanosoma brucei hypothetical protein, conserved 0.0013 0.0073 0.042
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0009 0.0007 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0073 0.042
Onchocerca volvulus 0.0031 0.0385 0.18
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0009 0.0007 0.0007
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.1708 0.1705
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Leishmania major cysteine peptidase A (CPA) 0.0017 0.014 0.0781
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Brugia malayi secreted modular calcium-binding protein 1 0.0022 0.0235 0.0234
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0022 0.0235 0.0234
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0916 0.1355
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0065 0.0979 0.1449
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.014 0.0812
Echinococcus granulosus 7TM GPCR rhodopsin 0.002 0.0208 0.0258
Brugia malayi nuclear hormone receptor 0.0065 0.0979 0.0978
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0713 0.1055
Toxoplasma gondii cathepsin CPL 0.0017 0.014 0.1192
Trypanosoma brucei DNA damage repair protein, putative 0.0013 0.0073 0.042
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0034 0.0449 0.0662
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0009 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0026 0.0299 0.0295
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0064 0.006
Echinococcus multilocularis alpha 1A adrenergic receptor 0.002 0.0208 0.0258
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0006
Onchocerca volvulus 0.0009 0.0007 0.0034
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0164
Echinococcus multilocularis Ankyrin 0.0014 0.0102 0.0125
Mycobacterium tuberculosis Conserved protein 0.0073 0.1122 0.1217
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0208 0.0204
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Loa Loa (eye worm) CYP4Cod1 0.0012 0.0064 0.006
Loa Loa (eye worm) hypothetical protein 0.0065 0.0979 0.0976
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Brugia malayi hypothetical protein 0.0034 0.0449 0.0447
Brugia malayi Serotonin/octopamine receptor family protein 7 0.002 0.0208 0.0206
Onchocerca volvulus Bile acid receptor homolog 0.0065 0.0979 0.4579
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0009 0.0007 0.0034
Schistosoma mansoni biogenic amine receptor 0.002 0.0208 0.0306
Schistosoma mansoni zinc finger protein 0.0031 0.0385 0.0568
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0175 0.2374
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Leishmania major DNA polymerase eta, putative 0.0041 0.056 0.3248
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.056 0.3271
Loa Loa (eye worm) TYRA-2 protein 0.002 0.0208 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0581 0.3393
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0355 0.2072
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0009 0.0007 0.0007
Onchocerca volvulus 0.0017 0.014 0.0655
Schistosoma mansoni amine GPCR 0.002 0.0208 0.0306
Loa Loa (eye worm) nuclear hormone receptor 0.0031 0.0385 0.0381
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0034
Onchocerca volvulus 0.002 0.0208 0.0971
Loa Loa (eye worm) hypothetical protein 0.0034 0.0449 0.0445
Entamoeba histolytica cysteine proteinase, putative 0.0011 0.0046 0.0259
Entamoeba histolytica hypothetical protein 0.0072 0.1099 0.6431
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0385 0.048
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0041 0.056 0.0556
Brugia malayi G protein-coupled receptor F59B2.13 0.002 0.0208 0.0206
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0009 0.0007 0.0007
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.056 0.3248
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0453 0.0451
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.002 0.0208 0.0971
Echinococcus multilocularis dna polymerase eta 0.0041 0.056 0.0698
Loa Loa (eye worm) hypothetical protein 0.0032 0.0412 0.0409
Brugia malayi TAR-binding protein 0.0062 0.0916 0.0915
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0713 0.4152
Schistosoma mansoni biogenic amine receptor 0.002 0.0208 0.0306
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1708 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0248 0.1446
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0032 0.0412 0.0514
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.014 0.0812
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0208 0.0306
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Echinococcus granulosus g-protein coupled receptor 0.002 0.0208 0.0258
Onchocerca volvulus 0.0073 0.1122 0.5246
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.014 0.0173
Plasmodium falciparum importin beta, putative 0.0028 0.034 0.9579
Brugia malayi nuclear hormone receptor family member nhr-6 0.0031 0.0385 0.0383
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.034 0.2986
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0449 0.0447
Schistosoma mansoni cpg binding protein 0.003 0.0366 0.054
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0009 0.0007 0.0009
Schistosoma mansoni organic anion transporter 0.0032 0.0412 0.0609
Onchocerca volvulus 0.0009 0.0007 0.0034
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0208 0.0258
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus granulosus dna polymerase eta 0.0041 0.056 0.0698
Brugia malayi hypothetical protein 0.002 0.0208 0.0206
Schistosoma mansoni hypothetical protein 0.0035 0.0453 0.0669
Brugia malayi sodium-independent organic anion transporter family protein 0.0032 0.0412 0.0411
Loa Loa (eye worm) hypothetical protein 0.0031 0.0385 0.0381
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.1122 0.166
Echinococcus granulosus g protein coupled receptor 0.002 0.0208 0.0258
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.014 0.0812
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.034 0.1984
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Onchocerca volvulus 0.0073 0.1122 0.5246
Giardia lamblia DNA damage repair protein 0.0013 0.0073 0.0932
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.056 0.3271
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Leishmania major DNA damage repair protein, putative 0.0013 0.0073 0.0387
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0183 0.3014 0.3768
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.1122 0.6434
Loa Loa (eye worm) hypothetical protein 0.0041 0.056 0.0556
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0006
Brugia malayi Cathepsin L-like precursor 0.0017 0.014 0.0139
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.002 0.0208 0.0258
Echinococcus granulosus snurportin 1 0.0301 0.5042 0.6305
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0355 0.1175
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0208 0.0258
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.0007
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0006
Echinococcus granulosus ubiquitin specific protease 41 0.0042 0.0581 0.0724
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.014 0.0812
Brugia malayi phosphofructokinase 0.0107 0.1708 0.1707
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0208 0.0306
Brugia malayi nuclear hormone receptor 0.0031 0.0385 0.0383
Brugia malayi G-protein coupled receptor 0.002 0.0208 0.0206
Schistosoma mansoni biogenic amine receptor 0.002 0.0208 0.0306
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0009 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.014 0.0812
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.073 0.0728
Echinococcus granulosus importin subunit beta 1 0.0028 0.034 0.0424
Brugia malayi G protein-coupled receptor 0.002 0.0208 0.0206
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Brugia malayi Death domain containing protein 0.0014 0.01 0.0098
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0916 0.0912
Schistosoma mansoni opsin-like receptor 0.002 0.0208 0.0306
Loa Loa (eye worm) hypothetical protein 0.0022 0.0235 0.0232
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.014 0.0812
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0009 0.0007 0.0052
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.0007
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0713 0.4172
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus multilocularis g protein coupled receptor 0.002 0.0208 0.0258
Onchocerca volvulus Peroxidase homolog 0.0026 0.0299 0.1398
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0581 0.0724
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.1122 0.1217
Echinococcus multilocularis fmrfamide receptor 0.002 0.0208 0.0258
Leishmania major DNA polymerase kappa, putative 0.0041 0.056 0.3248
Loa Loa (eye worm) hypothetical protein 0.0065 0.0979 0.0976
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.1122 0.6434
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0065 0.0979 0.0978
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0042 0.0581 0.3393
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0581 0.3393
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0006
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0385 0.048
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0299 0.0298
Brugia malayi hypothetical protein 0.0032 0.0412 0.0411
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0131 0.0162
Echinococcus multilocularis nuclear receptor nhr 48 0.0031 0.0385 0.048
Echinococcus multilocularis somatostatin receptor 0.002 0.0208 0.0258
Onchocerca volvulus 0.002 0.0208 0.0971
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0208 0.0306
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.014 0.0812
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0065 0.0979 0.1223
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0026 0.0299 0.0295
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0172 0.2825 0.3532
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Loa Loa (eye worm) hypothetical protein 0.0026 0.0299 0.0295
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0031 0.0385 0.0568
Brugia malayi beta-lactamase family protein 0.0073 0.1122 0.1121
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0916 0.0915
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0944 0.5521
Brugia malayi ubiquitin specific protease 14 0.0009 0.0007 0.0006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0183 0.3014 0.4463
Brugia malayi photoreceptor-specific nuclear receptor 0.0065 0.0979 0.0978
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0009 0.0007 0.0164
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0065 0.0979 0.1449
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.014 0.0812
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0031 0.0385 0.0381
Loa Loa (eye worm) hypothetical protein 0.0013 0.0073 0.0069
Echinococcus multilocularis neuropeptide receptor 0.002 0.0208 0.0258
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0009 0.0007 0.0009
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0248 0.1446
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0208 0.0258
Brugia malayi hypothetical protein 0.0031 0.0385 0.0383
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.014 0.0136
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0207 0.3423 0.3423
Brugia malayi Cathepsin L-like precursor 0.0011 0.0046 0.0044
Schistosoma mansoni survival motor neuron protein 0.0096 0.1515 0.2242
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.1708 1
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.01 0.0123
Leishmania major cathepsin L-like protease 0.0063 0.0944 0.5506
Brugia malayi Tachykinin-like peptides receptor 99D 0.002 0.0208 0.0206
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.014 0.0812
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0009 0.0007 0.0007
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0208 0.0306
Loa Loa (eye worm) hypothetical protein 0.0026 0.0299 0.0295
Leishmania major DNA polymerase eta, putative 0.0013 0.0073 0.0387
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0175 0.0217
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0208 0.0258
Brugia malayi Peroxidasin 0.0026 0.0299 0.0298
Echinococcus multilocularis cpg binding protein 0.003 0.0366 0.0456
Schistosoma mansoni DNA polymerase IV / kappa 0.0013 0.0073 0.0106
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.056 0.0558
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0175 0.1548
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0208 0.0204
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0065 0.0979 0.0976
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0003
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0208 0.0306
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0944 0.5521
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0065 0.0979 0.0976
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.014 0.0812
Giardia lamblia DINP protein human, muc B family 0.0041 0.056 0.7822
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0284 0.2518
Schistosoma mansoni ap endonuclease 0.0019 0.0175 0.0257
Loa Loa (eye worm) hypothetical protein 0.0073 0.1122 0.1118
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Brugia malayi Nuclear hormone receptor-like 1 0.0065 0.0979 0.0978
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.056 0.0495
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0009 0.0007 0.0007
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.1708 0.2528
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0212 0.0263
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.0046 0.0065
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0385 0.0383
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Brugia malayi ecdysone receptor 0.0031 0.0385 0.0383
Brugia malayi nuclear receptor NHR-88 0.0065 0.0979 0.0978
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Schistosoma mansoni organic anion transporter 0.0032 0.0412 0.0609
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0713 0.4172
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0208 0.0306
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0208 0.0258
Echinococcus multilocularis jun protein 0.0169 0.2763 0.3455
Onchocerca volvulus 0.0017 0.014 0.0655
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0009 0.0007 0.0007
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0175 0.1016
Brugia malayi sodium-independent organic anion transporter family protein 0.0032 0.0412 0.0411
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0009 0.0007 0.0007
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0183 0.3014 0.3768
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0065 0.0979 0.1223
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.1122 0.1217
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0944 0.5521
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0009 0.0007 0.0009
Brugia malayi CXXC zinc finger family protein 0.0028 0.0338 0.0337
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0013 0.0073 0.0591
Brugia malayi prostaglandin transporter 0.0032 0.0412 0.0411
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.014 0.0812
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.1122 0.6565
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0713 0.4152
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0011 0.0046 0.0042
Loa Loa (eye worm) hypothetical protein 0.0031 0.0385 0.0381
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0009 0.0007 0.0007
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0006
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0299 0.0298
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0208 0.0258
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0065 0.0979 0.0976
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.056 0.3271
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Brugia malayi hypothetical protein 0.0472 0.7995 0.7995
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0107 0.1708 1
Plasmodium falciparum DNA repair protein REV1, putative 0.0013 0.0073 0.2027
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0355 0.2072
Mycobacterium ulcerans hypothetical protein 0.0073 0.1122 0.6434
Onchocerca volvulus 0.0028 0.0338 0.1583
Echinococcus multilocularis neuropeptide receptor 0.002 0.0208 0.0258
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0208 0.0306
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0007 0.0034
Brugia malayi nuclear receptor RXR 0.0034 0.0449 0.0447
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trypanosoma brucei unspecified product 0.0041 0.056 0.3271
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0007 0.0034
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.1112 0.1389
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0006
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0009 0.0007 0.0007
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0385 0.048
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0009 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0007 0.0034
Loa Loa (eye worm) hypothetical protein 0.0026 0.0299 0.0295
Brugia malayi Cathepsin L-like cysteine proteinase 0.0011 0.0046 0.0044
Loa Loa (eye worm) hypothetical protein 0.0042 0.0581 0.0577
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.002 0.0208 0.0306
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Onchocerca volvulus 0.0132 0.2139 1
Mycobacterium ulcerans lipase LipD 0.0073 0.1122 0.6434
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0009 0.0007 0.0007
Entamoeba histolytica deoxycytidyl transferase, putative 0.0041 0.056 0.3271
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0065 0.0979 0.0976
Echinococcus multilocularis orexin receptor type 2 0.002 0.0208 0.0258
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0009 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0713 0.4172
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0284 0.7979
Leishmania major hypothetical protein, conserved 0.0073 0.1122 0.6554
Trichomonas vaginalis esterase, putative 0.0073 0.1122 0.6565
Onchocerca volvulus 0.0065 0.0979 0.4579
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.1122 0.1118
Echinococcus multilocularis neuropeptide s receptor 0.002 0.0208 0.0258
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.1122 0.1402
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Loa Loa (eye worm) hypothetical protein 0.0034 0.0449 0.0445
Echinococcus multilocularis agrin 0.0022 0.0235 0.0293
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0009 0.0007 0.0034
Echinococcus granulosus fmrfamide receptor 0.002 0.0208 0.0258
Brugia malayi follicle stimulating hormone receptor 0.0248 0.4136 0.4135
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0041 0.056 0.0698
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0208 0.0258
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0065 0.0979 0.1449
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trichomonas vaginalis ran, putative 0.0021 0.0212 0.1233
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1708 1
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0009 0.0007 0.0164
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0183 0.3014 0.3768
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.002 0.0208 0.0258
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0212 0.1835
Loa Loa (eye worm) hypothetical protein 0.002 0.0208 0.0204
Echinococcus granulosus cathepsin l1 0.0017 0.014 0.0173
Brugia malayi STAT protein, DNA binding domain containing protein 0.0337 0.5678 0.5678
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0916 0.1355
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0034
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0208 0.0258
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0355 1
Brugia malayi Melatonin receptor type 1A 0.002 0.0208 0.0206
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0007 0.0034
Brugia malayi bZIP transcription factor family protein 0.0169 0.2763 0.2762

Activities

Activity type Activity value Assay description Source Reference
Activation (functional) = 49 % Evaluated for Beta-3 adrenergic receptor activity by adenylyl cyclase activation as % of the maximal stimulation with isoproterenol at 100 nM ChEMBL. 9873496
Activation (functional) = 49 % Evaluated for Beta-3 adrenergic receptor activity by adenylyl cyclase activation as % of the maximal stimulation with isoproterenol at 100 nM ChEMBL. 9873496
Bioavailabiility (ADMET) = 4 Bioavailability in rat ChEMBL. 9925722
EC50 (functional) = 13 nM Evaluated for its agonist activity against human Beta-3 adrenergic receptor ChEMBL. 9873496
EC50 (functional) = 13 nM Evaluated for its agonist activity against human Beta-3 adrenergic receptor ChEMBL. 9873496
F (ADMET) = 41 Bioavailability in dog ChEMBL. 9925722
F (ADMET) = 47 Bioavailability in dog ChEMBL. 9925722
IC50 (binding) = 540 nM Evaluated for its agonist activity and the binding affinity against human Beta-2 adrenergic receptor in membranes from chinese hamster ovary cell ChEMBL. 9873496
IC50 (binding) = 540 nM Evaluated for its agonist activity and the binding affinity against human Beta-2 adrenergic receptor in membranes from chinese hamster ovary cell ChEMBL. 9873496
IC50 (binding) = 1800 nM Evaluated for its agonist activity and the binding affinity against human Beta-1 adrenergic receptor in membranes from chinese hamster ovary cell ChEMBL. 9873496
IC50 (binding) = 1800 nM Evaluated for its agonist activity and the binding affinity against human Beta-1 adrenergic receptor in membranes from chinese hamster ovary cell ChEMBL. 9873496

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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