Detailed information for compound 1124189

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 363.837 | Formula: C15H26ClN3O5
  • H donors: 2 H acceptors: 4 LogP: 0.85 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)CN1C(=O)CC[C@@H](C1=O)NC(=O)[C@H](CC(C)C)N.Cl
  • InChi: 1S/C15H25N3O5.ClH/c1-4-23-13(20)8-18-12(19)6-5-11(15(18)22)17-14(21)10(16)7-9(2)3;/h9-11H,4-8,16H2,1-3H3,(H,17,21);1H/t10-,11-;/m0./s1
  • InChiKey: RGTDVHRSMIRJRX-ACMTZBLWSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0035 0.0125 0.138
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0091 0.009
Plasmodium falciparum protein kinase 7 0.0949 0.5344 0.6625
Leishmania major phosphoglycerate kinase B, cytosolic 0.0167 0.0877 1
Trichomonas vaginalis glucose transporter, putative 0.0104 0.052 0.1945
Loa Loa (eye worm) doublecortin family protein 0.0022 0.005 0.0084
Loa Loa (eye worm) hypothetical protein 0.0022 0.005 0.0084
Schistosoma mansoni ap endonuclease 0.0022 0.0052 0.006
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0019 0.0033 0.0319
Loa Loa (eye worm) MH1 domain-containing protein 0.0015 0.0013 0.0021
Plasmodium falciparum calcium-dependent protein kinase 1 0.0103 0.0512 0.0635
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0082 0.0888
Brugia malayi neuropeptide F receptor 0.0015 0.0012 0.002
Trypanosoma cruzi hexose transporter, putative 0.0104 0.052 0.59
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0201 0.0753
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.1612 0.6036
Onchocerca volvulus 0.0015 0.0012 0.0044
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0373 0.1398
Echinococcus multilocularis microtubule associated protein 2 0.1507 0.8535 0.8535
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0102 0.1114
Echinococcus granulosus Threonyl tRNA synthetase C 0.0019 0.0033 0.0038
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0021 0.0042 0.0431
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0012 0.0014
Toxoplasma gondii ABC1 family protein 0.0079 0.0373 0.0698
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0103 0.0512 0.0958
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0017 0.002 0.0175
Plasmodium vivax phosphoglycerate kinase, putative 0.0167 0.0877 0.1087
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Leishmania major protein kinase, putative 0.0103 0.0512 0.5814
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0102 0.1114
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0012 0.0014
Schistosoma mansoni hypothetical protein 0.0015 0.0012 0.0014
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0069 0.0319 0.3597
Giardia lamblia Phosphoglycerate kinase 0.0167 0.0877 0.4513
Trypanosoma cruzi hexose transporter, putative 0.0047 0.0194 0.2173
Trichomonas vaginalis sugar transporter, putative 0.0104 0.052 0.1945
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0101 0.05 0.0586
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0012 0.0014
Echinococcus multilocularis g-protein coupled receptor 0.0015 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0047 0.0194 0.0329
Loa Loa (eye worm) RNA binding protein 0.0065 0.0297 0.0503
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0336 0.1843 0.1843
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0186 0.0697
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0012 0.0014
Onchocerca volvulus 0.0055 0.0237 0.0887
Echinococcus multilocularis solute carrier family 22 0.0047 0.0194 0.0194
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.023 0.0862
Loa Loa (eye worm) TYRA-2 protein 0.0015 0.0012 0.002
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0085 0.041 0.0409
Brugia malayi Cam kinase protein 1 0.0103 0.0512 0.0868
Echinococcus multilocularis dnaJ subfamily B 0.0435 0.2412 0.2412
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0103 0.0512 0.0599
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0103 0.0512 0.0868
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0069 0.0319 0.3597
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0624 0.0624
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0012 0.0014
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0035 0.0125 0.138
Schistosoma mansoni amine GPCR 0.0015 0.0012 0.0014
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0103 0.0512 0.0868
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Loa Loa (eye worm) CYP4Cod1 0.0014 0.0005 0.0007
Leishmania major phosphatidylinositol 3-kinase, putative 0.0035 0.0127 0.1407
Brugia malayi sulfakinin receptor protein 0.0015 0.0012 0.002
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0047 0.0194 0.0681
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0049 0.0204 0.0762
Mycobacterium ulcerans lipase LipD 0.0079 0.0373 0.4224
Plasmodium vivax SET domain protein, putative 0.0061 0.0274 0.0339
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0012 0.0012
Trichomonas vaginalis Heterochromatin protein, putative 0.0013 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.001 0.0012
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0167 0.0877 0.1641
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0136 0.0158
Mycobacterium ulcerans hypothetical protein 0.0028 0.0082 0.0888
Trichomonas vaginalis sugar transporter, putative 0.0104 0.052 0.1945
Trypanosoma brucei glucose transporter, putative 0.0104 0.052 0.59
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0005 0.0007
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0022 0.0052 0.0542
Brugia malayi hypothetical protein 0.0015 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0062 0.0278 0.0471
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Schistosoma mansoni smad1 5 8 and 0.0015 0.0013 0.0015
Echinococcus multilocularis chromobox protein 1 0.0081 0.0388 0.0387
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0102 0.0119
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0035 0.0127 0.0149
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0176 0.0928 0.1573
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0189 0.1003 0.1701
Echinococcus granulosus p2X purinoceptor 4 0.0188 0.0997 0.1167
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0047 0.0194 0.2173
Echinococcus multilocularis GPCR, family 2 0.0085 0.041 0.0409
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0046 0.0078
Brugia malayi hypothetical protein 0.0047 0.0194 0.0329
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0186 0.0698
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0156 0.0155
Trypanosoma cruzi glucose transporter, putative 0.0047 0.0194 0.2173
Brugia malayi neuropeptide F receptor 0.0015 0.0012 0.002
Onchocerca volvulus 0.0047 0.0194 0.0726
Leishmania major modification methylase-like protein 0.002 0.0041 0.0414
Schistosoma mansoni hypothetical protein 0.0014 0.0005 0.0005
Entamoeba histolytica hypothetical protein 0.004 0.0154 0.0805
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0015 0.0012 0.0012
Brugia malayi Phosphoglycerate kinase 0.0061 0.0274 0.0465
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0388 0.1451
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0022 0.0083
Brugia malayi hypothetical protein 0.0015 0.0012 0.002
Schistosoma mansoni hypothetical protein 0.0057 0.0251 0.0294
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.0373 0.4224
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.005 0.005
Schistosoma mansoni ap endonuclease 0.0022 0.0052 0.006
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0035 0.0127 0.0149
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.002 0.0039 0.0039
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0176 0.0928 0.1573
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0046 0.0078
Echinococcus multilocularis p2X purinoceptor 4 0.0188 0.0997 0.0996
Echinococcus granulosus histone acetyltransferase KAT2B 0.015 0.0781 0.0915
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0015 0.0012 0.0014
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0103 0.0512 0.0958
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.004 0.015
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0075 0.0088
Schistosoma mansoni sugar transporter 0.0047 0.0194 0.0227
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0046 0.0054
Schistosoma mansoni hypothetical protein 0.1118 0.6311 0.7393
Loa Loa (eye worm) hypothetical protein 0.0047 0.0194 0.0329
Mycobacterium ulcerans beta-lactamase 0.0079 0.0373 0.4224
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0012 0.0014
Onchocerca volvulus 0.0047 0.0194 0.0726
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.1612 0.6036
Toxoplasma gondii target of rapamycin (TOR), putative 0.0056 0.0245 0.0458
Loa Loa (eye worm) latrophilin receptor protein 2 0.0085 0.041 0.0694
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0013 0.0049
Toxoplasma gondii exonuclease III APE 0.0022 0.0052 0.0096
Echinococcus granulosus microtubule associated protein 2 0.1507 0.8535 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0046 0.0078
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.002 0.0039 0.0393
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Onchocerca volvulus 0.0028 0.0082 0.0306
Trichomonas vaginalis glucose transporter, putative 0.0104 0.052 0.1945
Brugia malayi chromobox protein homolog 3 0.0045 0.0184 0.0312
Leishmania major hypothetical protein, conserved 0.0017 0.002 0.0175
Toxoplasma gondii facilitative glucose transporter GT1 0.0336 0.1843 0.3448
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0075 0.0353 0.3989
Leishmania major lysyl-tRNA synthetase, putative 0.0075 0.0353 0.3989
Brugia malayi MH2 domain containing protein 0.0015 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0021 0.0042 0.0071
Chlamydia trachomatis phosphoglycerate kinase 0.0167 0.0877 1
Mycobacterium tuberculosis Probable hydrolase 0.0079 0.0373 0.1323
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0078
Brugia malayi Latrophilin receptor protein 2 0.0085 0.041 0.0694
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0297 0.0348
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0103 0.0512 0.0868
Loa Loa (eye worm) hypothetical protein 0.0167 0.0877 0.1488
Echinococcus granulosus peregrin 0.0033 0.0112 0.0131
Loa Loa (eye worm) hypothetical protein 0.0082 0.0392 0.0665
Echinococcus granulosus RUN 0.0022 0.005 0.0058
Echinococcus granulosus disco interacting protein 2 0.0041 0.0158 0.0184
Brugia malayi larval opioid receptor 0.0015 0.0012 0.002
Onchocerca volvulus 0.0079 0.0373 0.1396
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.002 0.0175
Mycobacterium tuberculosis Probable lipase LipE 0.0079 0.0373 0.1323
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0102 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0194 0.0728
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0012 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0046 0.0078
Echinococcus granulosus dnaJ subfamily B 0.0435 0.2412 0.2825
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0019 0.0033 0.0319
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0091 0.0169
Trichomonas vaginalis sugar transport protein, putative 0.0047 0.0194 0.0728
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0069 0.0319 0.0318
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.004 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Schistosoma mansoni hypothetical protein 0.0085 0.041 0.0479
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0017 0.002 0.0037
Trypanosoma brucei glucose transporter, putative 0.0104 0.052 0.59
Loa Loa (eye worm) hypothetical protein 0.0025 0.007 0.0118
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0012 0.0014
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0388 0.1451
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0144 0.0749 0.8528
Plasmodium vivax hypothetical protein, conserved 0.0079 0.0373 0.0462
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0624 0.71
Leishmania major phosphatidylinositol kinase related protein, putative 0.0022 0.005 0.0517
Schistosoma mansoni hypothetical protein 0.0029 0.0091 0.0106
Trichomonas vaginalis sugar transporter, putative 0.0104 0.052 0.1945
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0184 0.069
Brugia malayi hypothetical protein 0.028 0.1525 0.2587
Onchocerca volvulus 0.0015 0.0012 0.0044
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0082 0.0888
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0005 0.0007
Brugia malayi Cytochrome P450 family protein 0.0014 0.0005 0.0007
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0295 0.1612 0.8464
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0078
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0108 0.0406
Trypanosoma brucei phosphoglycerate kinase 0.0061 0.0274 0.309
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0082 0.0888
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Toxoplasma gondii FATC domain-containing protein 0.0035 0.0125 0.0233
Loa Loa (eye worm) hypothetical protein 0.002 0.0039 0.0066
Echinococcus granulosus TGF beta signal transducer SmadC 0.0015 0.0013 0.0015
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0015 0.0012 0.0012
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0075 0.0353 0.3989
Echinococcus multilocularis survival motor neuron protein 1 0.028 0.1525 0.1525
Loa Loa (eye worm) hypothetical protein 0.0047 0.0194 0.0329
Brugia malayi Dopamine receptor protein 1 0.0015 0.0012 0.002
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0079 0.0373 0.1323
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0274 0.309
Plasmodium falciparum calcium-dependent protein kinase 3 0.0103 0.0512 0.0635
Loa Loa (eye worm) hypothetical protein 0.0079 0.0373 0.0633
Schistosoma mansoni hypothetical protein 0.0015 0.0012 0.0014
Schistosoma mansoni hypothetical protein 0.004 0.0154 0.018
Schistosoma mansoni hypothetical protein 0.0015 0.0012 0.0014
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0102 0.1114
Leishmania major myo-inositol/proton symporter (MIT) 0.0047 0.0194 0.2173
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0015 0.0012 0.0014
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0274 0.309
Loa Loa (eye worm) Smad1 0.0015 0.0013 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0125 0.0469
Giardia lamblia Fructose-bisphosphate aldolase 0.0295 0.1612 0.8437
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0047 0.0194 0.0681
Plasmodium vivax calcium-dependent protein kinase, putative 0.0103 0.0512 0.0635
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.026 0.0973
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0059 0.026 0.2925
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0021
Onchocerca volvulus 0.0015 0.0012 0.0044
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.1003 0.1175
Onchocerca volvulus Putative transporter 0.0047 0.0194 0.0726
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0102 0.0119
Schistosoma mansoni smad1 5 8 and 0.0015 0.0013 0.0015
Brugia malayi cytochrome P450 0.0014 0.0005 0.0007
Leishmania major phosphoglycerate kinase C, glycosomal 0.0167 0.0877 1
Schistosoma mansoni hypothetical protein 0.0015 0.0013 0.0015
Onchocerca volvulus 0.0015 0.0012 0.0044
Echinococcus granulosus synaptic vesicle 2 protein 0.0047 0.0194 0.0227
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0012 0.0012
Loa Loa (eye worm) melatonin receptor type 1A 0.0015 0.0012 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0186 0.0698
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0131 0.0676 0.0791
Schistosoma mansoni amine GPCR 0.0015 0.0012 0.0014
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0035 0.0127 0.1407
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.1612 0.6036
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.004 0.015
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.004 0.015
Brugia malayi Dopamine receptor protein 2 0.0015 0.0012 0.002
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0079 0.0373 0.0633
Loa Loa (eye worm) hypothetical protein 0.0021 0.0042 0.0071
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0144 0.0749 0.2671
Trypanosoma brucei THT1 - hexose transporter, putative 0.0104 0.052 0.59
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Echinococcus granulosus solute carrier family 22 0.0047 0.0194 0.0227
Brugia malayi hypothetical protein 0.0015 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0045 0.0184 0.0312
Brugia malayi Sugar transporter family protein 0.0047 0.0194 0.0329
Echinococcus granulosus cpg binding protein 0.0067 0.0306 0.0358
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0019 0.0033 0.0319
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0184 0.0688
Brugia malayi CXXC zinc finger family protein 0.0065 0.0296 0.0502
Brugia malayi G protein-coupled receptor F59B2.13 0.0015 0.0012 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0012 0.0014
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.002 0.0041 0.005
Mycobacterium tuberculosis Conserved protein 0.0079 0.0373 0.1323
Loa Loa (eye worm) hypothetical protein 0.0022 0.0052 0.0088
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0036 0.0112
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0102 0.0102
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0028 0.0082 0.0139
Trypanosoma brucei glucose transporter, putative 0.0104 0.052 0.59
Echinococcus granulosus tumor protein p63 0.0738 0.4141 0.4851
Schistosoma mansoni neuropeptide receptor 0.0015 0.0012 0.0014
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Loa Loa (eye worm) hypothetical protein 0.0025 0.007 0.0118
Echinococcus granulosus Chromobox protein 3 0.0013 0 0.00000001696
Echinococcus multilocularis lamin dm0 0.0055 0.0237 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0624 0.71
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0046 0.0054
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0046 0.0171
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0019 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0186 0.0698
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0019 0.0033 0.0122
Echinococcus multilocularis G-protein coupled receptor, putative 0.0015 0.0012 0.0012
Brugia malayi hypothetical protein 0.0015 0.0012 0.002
Schistosoma mansoni rab6-interacting 0.0022 0.005 0.0058
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0047 0.0194 0.2173
Schistosoma mansoni coup transcription factor 0.0021 0.0046 0.0054
Treponema pallidum prolyl-tRNA synthetase 0.0036 0.0128 0.0604
Brugia malayi hypothetical protein 0.004 0.0154 0.026
Onchocerca volvulus 0.0015 0.0012 0.0044
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0041 0.0158 0.0184
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0035 0.0125 0.0212
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0156 0.0586
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0039 0.0146
Schistosoma mansoni amine GPCR 0.0015 0.0012 0.0014
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0085 0.041 0.0409
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0052 0.0064
Giardia lamblia PHD finger protein 15 0.0029 0.0091 0.031
Toxoplasma gondii sugar transporter ST3 0.0047 0.0194 0.0363
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0046 0.0054
Echinococcus multilocularis somatostatin receptor 0.0015 0.0012 0.0012
Echinococcus multilocularis glycyl tRNA synthetase 0.0019 0.0033 0.0032
Echinococcus multilocularis smad 0.0015 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.004 0.0151 0.0256
Entamoeba histolytica acyl-CoA synthetase, putative 0.0028 0.0082 0.0429
Mycobacterium leprae conserved hypothetical protein 0.0017 0.002 0.0175
Loa Loa (eye worm) hypothetical protein 0.0036 0.0128 0.0217
Echinococcus granulosus 7TM GPCR rhodopsin 0.0015 0.0012 0.0014
Onchocerca volvulus 0.0065 0.0296 0.1108
Onchocerca volvulus 0.0015 0.0012 0.0044
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0069 0.0319 0.054
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0022 0.0052 0.0104
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.1612 0.6036
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0035 0.0127 0.1407
Echinococcus granulosus serotonin receptor 0.0015 0.0012 0.0014
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0082 0.0888
Trypanosoma brucei phosphoglycerate kinase, putative 0.0061 0.0274 0.309
Onchocerca volvulus 0.0015 0.0012 0.0044
Schistosoma mansoni phosphoglycerate kinase 0.0167 0.0877 0.1027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0012 0.0012
Echinococcus granulosus beta LACTamase domain containing family member 0.0079 0.0373 0.0437
Schistosoma mansoni sugar transporter 0.0047 0.0194 0.0227
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0046 0.0078
Brugia malayi hypothetical protein 0.0015 0.0012 0.002
Schistosoma mansoni phosphoglycerate kinase 0.0167 0.0877 0.1027
Mycobacterium tuberculosis Conserved protein 0.0079 0.0373 0.1323
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0103 0.0512 0.0635
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Mycobacterium leprae Probable lipase LipE 0.0079 0.0373 0.4224
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0126 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Leishmania major glucose transporter, lmgt2 0.0104 0.052 0.59
Toxoplasma gondii transporter, major facilitator family protein 0.0047 0.0194 0.0363
Schistosoma mansoni opsin-like receptor 0.0015 0.0012 0.0014
Trypanosoma brucei phosphoglycerate kinase 0.0167 0.0877 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0086 0.0145
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0079 0.0373 0.1323
Brugia malayi Sugar transporter family protein 0.0047 0.0194 0.0329
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0069 0.0319 0.3597
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0189 0.1003 0.1175
Brugia malayi AKH receptor 0.0015 0.0012 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0012 0.0012
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0204 0.0763
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0059 0.026 0.2925
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.005 0.0517
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0046 0.0078
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0075 0.0353 0.3989
Trypanosoma brucei glucose transporter, putative 0.0104 0.052 0.59
Plasmodium vivax glycine--tRNA ligase, putative 0.0019 0.0033 0.004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0046 0.0046
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0073 0.0342 0.0342
Brugia malayi hypothetical protein 0.0015 0.0012 0.002
Mycobacterium ulcerans hypothetical protein 0.0079 0.0373 0.4224
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0052 0.0195
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0091 0.0169
Loa Loa (eye worm) hypothetical protein 0.0021 0.0042 0.0071
Toxoplasma gondii hypothetical protein 0.0087 0.0422 0.079
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0184 0.0689
Loa Loa (eye worm) hypothetical protein 0.0047 0.0194 0.0329
Echinococcus granulosus survival motor neuron protein 1 0.028 0.1525 0.1787
Brugia malayi RE15519p 0.0015 0.0012 0.002
Brugia malayi Bromodomain containing protein 0.0033 0.0112 0.019
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0092 0.0156
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1045 0.5896 1
Trichomonas vaginalis hypothetical protein 0.0013 0 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0012 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0297 0.0348
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0039 0.0146
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0373 0.1398
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0046 0.0078
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0184 0.0227
Loa Loa (eye worm) hypothetical protein 0.0047 0.0194 0.0329
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0101 0.05 0.0848
Schistosoma mansoni loxhd1 0.0022 0.005 0.0058
Loa Loa (eye worm) hypothetical protein 0.0079 0.0373 0.0633
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0117 0.0595 0.1114
Plasmodium vivax hexose transporter 0.0336 0.1843 0.2284
Schistosoma mansoni survival motor neuron protein 0.0057 0.0251 0.0294
Loa Loa (eye worm) cytochrome P450 0.0014 0.0005 0.0007
Echinococcus multilocularis p2X purinoceptor 4 0.0188 0.0997 0.0996
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0079 0.0373 0.0633
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0015 0.0012 0.0012
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.002 0.0041 0.0414
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0201 0.0753
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0091 0.0106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0171 0.0641
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0015 0.0012 0.0014
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0047 0.0194 0.0329
Loa Loa (eye worm) hypothetical protein 0.0055 0.0237 0.0402
Schistosoma mansoni cpg binding protein 0.0067 0.0306 0.0358
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0015 0.0012 0.0012
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0136 0.0158
Chlamydia trachomatis lysine--tRNA ligase 0.0075 0.0353 0.3791
Brugia malayi Serotonin receptor 0.0015 0.0012 0.002
Leishmania major glucose transporter, lmgt3 0.0104 0.052 0.59
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0127 0.0477
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0295 0.1612 0.8464
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0167 0.0877 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.0542 0.0918
Echinococcus multilocularis phosphoglycerate kinase 1 0.0167 0.0877 0.0877
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0022 0.0052 0.017
Brugia malayi jmjC domain containing protein 0.0037 0.0136 0.0229
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0154 0.018
Plasmodium vivax proline--tRNA ligase, putative 0.0117 0.0595 0.0738
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0204 0.0763
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0102 0.0102
Schistosoma mansoni amine GPCR 0.0015 0.0012 0.0014
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0046 0.0046
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0167 0.0877 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.004 0.015
Schistosoma mansoni intermediate filament proteins 0.0055 0.0237 0.0277
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0069 0.0319 0.1671
Brugia malayi Smad1 0.0015 0.0013 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0245 0.0917
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0015 0.0013 0.0013
Echinococcus granulosus smad 0.0015 0.0013 0.0015
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0015 0.0012 0.0012
Entamoeba histolytica hypothetical protein 0.0075 0.0353 0.1851
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.1612 0.6036
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0017 0.002 0.0175
Echinococcus granulosus g protein coupled receptor 0.0015 0.0012 0.0014
Schistosoma mansoni smad 0.0015 0.0013 0.0015
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0117 0.0595 0.677
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0028 0.0082 0.0888
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0162 0.0201
Schistosoma mansoni protein kinase 0.0103 0.0512 0.0599
Loa Loa (eye worm) hypothetical protein 0.0047 0.0194 0.0329
Mycobacterium ulcerans hypothetical protein 0.0017 0.002 0.0175
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0046 0.0078
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0047 0.0194 0.1915
Schistosoma mansoni lipoxygenase 0.0131 0.0676 0.0791
Schistosoma mansoni polycystin 1-related 0.0022 0.005 0.0058
Loa Loa (eye worm) hypothetical protein 0.0061 0.0274 0.0464
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0078
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0184 0.0343
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0357 0.0417
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.005 0.0058
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0022 0.0052 0.0097
Trypanosoma brucei glucose transporter, putative 0.0104 0.052 0.59
Brugia malayi Ets-domain containing protein 0.0072 0.0338 0.0572
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.052 0.1945
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0012 0.0012
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0015 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0021 0.0042 0.0071
Loa Loa (eye worm) hypothetical protein 0.0047 0.0194 0.0329
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0127 0.0477
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0237 0.0402
Echinococcus multilocularis RUN 0.0022 0.005 0.005
Plasmodium falciparum calcium-dependent protein kinase 5 0.0103 0.0512 0.0635
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0274 0.0512
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0012 0.0014
Schistosoma mansoni adenoreceptor 0.0015 0.0012 0.0014
Brugia malayi G protein-coupled receptor 0.0015 0.0012 0.002
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0039 0.0066
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0012 0.0014
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0047 0.0194 0.2173
Entamoeba histolytica hypothetical protein 0.004 0.0154 0.0805
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0297 0.0503
Schistosoma mansoni neuropeptide f receptor 76f 0.0015 0.0012 0.0014
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0101 0.05 0.2625
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0069 0.0319 0.1671
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0189 0.1003 0.1003
Schistosoma mansoni P2X receptor subunit 0.0188 0.0997 0.1167
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0274 0.309
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0015 0.0012 0.002
Schistosoma mansoni chromobox protein 0.0081 0.0388 0.0454
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0015 0.0012 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0046 0.0078
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0015 0.0013 0.0013
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0015 0.0012 0.0014
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0103 0.0512 0.0512
Echinococcus multilocularis serine protein kinase ATM 0.0035 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0046 0.0054
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0012 0.0014
Schistosoma mansoni P2X receptor subunit 0.0062 0.0278 0.0325
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0336 0.1843 0.2159
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0078
Onchocerca volvulus 0.0074 0.035 0.1308
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0012 0.0012
Brugia malayi Major Facilitator Superfamily protein 0.0047 0.0194 0.0329
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0046 0.0054
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0154 0.018
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0019 0.0033 0.0032
Trypanosoma brucei glucose transporter 1E 0.0104 0.052 0.59
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0019 0.0033 0.0169
Onchocerca volvulus 0.0022 0.005 0.0186
Onchocerca volvulus 0.0015 0.0012 0.0044
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0015 0.0012 0.0014
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0012 0.002
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0319 0.1193
Schistosoma mansoni cpg binding protein 0.0067 0.0306 0.0358
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0046 0.0078
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0078
Echinococcus granulosus g-protein coupled receptor 0.0015 0.0012 0.0014
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.002 0.0041 0.005
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0336 0.1843 0.1843
Echinococcus multilocularis p2X purinoceptor 4 0.0188 0.0997 0.0996
Brugia malayi Tachykinin-like peptides receptor 99D 0.0015 0.0012 0.002
Onchocerca volvulus 0.0079 0.0373 0.1396
Loa Loa (eye worm) sugar transporter 0.0336 0.1843 0.3125
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0069 0.0319 0.3597
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0042 0.0135
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Plasmodium falciparum hexose transporter 0.0336 0.1843 0.2284
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0012 0.0014
Echinococcus multilocularis Smad4 0.0015 0.0013 0.0013
Plasmodium vivax threonine--tRNA ligase, putative 0.0019 0.0033 0.004
Schistosoma mansoni neuropeptide receptor 0.0015 0.0012 0.0014
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0543 0.3024 0.5659
Onchocerca volvulus 0.0021 0.0046 0.0171
Onchocerca volvulus 0.0022 0.005 0.0186
Loa Loa (eye worm) hypothetical protein 0.0183 0.0972 0.1648
Schistosoma mansoni hypothetical protein 0.0435 0.2412 0.2825
Schistosoma mansoni glycyl-tRNA synthetase 0.0019 0.0033 0.0038
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Toxoplasma gondii sugar transporter ST2 0.0047 0.0194 0.0363
Brugia malayi ORL1-like opioid receptor 0.0015 0.0012 0.002
Echinococcus multilocularis disco interacting protein 2 0.0041 0.0158 0.0157
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0066 0.03 0.1123
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0015 0.0012 0.002
Echinococcus granulosus g protein coupled receptor 0.0015 0.0012 0.0014
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0102 0.019
Brugia malayi Major Facilitator Superfamily protein 0.0047 0.0194 0.0329
Loa Loa (eye worm) hypothetical protein 0.0268 0.1457 0.2471
Brugia malayi major facilitator superfamily protein 0.0047 0.0194 0.0329
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0012 0.0014
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0012 0.0012
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0082 0.0139
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0046 0.0078
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0046 0.0054
Loa Loa (eye worm) heterochromatin protein 1 0.0081 0.0388 0.0657
Trypanosoma cruzi hexose transporter, putative 0.0104 0.052 0.59
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0101 0.05 0.1873
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0336 0.1843 0.2159
Brugia malayi lysyl-tRNA synthetase 0.0075 0.0353 0.0598
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0046 0.0078
Loa Loa (eye worm) hypothetical protein 0.0079 0.0373 0.0633
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0012 0.0014
Entamoeba histolytica hypothetical protein 0.004 0.0154 0.0805
Onchocerca volvulus Neuropeptide F receptor homolog 0.0015 0.0012 0.0044
Schistosoma mansoni glucose transport protein 0.0336 0.1843 0.2159
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.005 0.0062
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0075 0.0075
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0036 0.0112
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0017 0.002 0.0175
Echinococcus granulosus solute carrier family 22 0.0047 0.0194 0.0227
Loa Loa (eye worm) hypothetical protein 0.0047 0.0194 0.0329
Echinococcus granulosus GPCR family 2 0.0085 0.041 0.0479
Onchocerca volvulus 0.0015 0.0012 0.0044
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Leishmania major glucose transporter/membrane transporter D2, putative 0.0104 0.052 0.59
Loa Loa (eye worm) hypothetical protein 0.0101 0.05 0.0848
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0046 0.0046
Schistosoma mansoni neuropeptide receptor 0.0015 0.0012 0.0014
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.005 0.0058
Toxoplasma gondii lysine-tRNA ligase 0.0075 0.0353 0.0659
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.004 0.015
Echinococcus multilocularis lysyl tRNA synthetase 0.0075 0.0353 0.0352
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0091 0.0153
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0245 0.0917
Schistosoma mansoni hypothetical protein 0.0085 0.041 0.0479
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0154 0.0806 0.0944
Onchocerca volvulus 0.0047 0.0194 0.0726
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0046 0.0054
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0082 0.0278
Schistosoma mansoni gabp alpha 0.0072 0.0338 0.0395
Mycobacterium tuberculosis Probable esterase LipL 0.0079 0.0373 0.1323
Plasmodium falciparum protein kinase 6 0.1425 0.8066 1
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0052 0.0195
Leishmania major hypothetical protein, conserved 0.0079 0.0373 0.4224
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0012 0.0014
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0184 0.0215
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0012 0.0012
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0046 0.0054
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0373 0.0437
Loa Loa (eye worm) hypothetical protein 0.0021 0.0042 0.0071
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0221 0.0373
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0021 0.0042 0.0116
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0274 0.309
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0012 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.1612 0.6036
Loa Loa (eye worm) hypothetical protein 0.0075 0.0353 0.0598
Trypanosoma cruzi hexose transporter, putative 0.0057 0.025 0.2809
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0117 0.0595 0.677
Echinococcus granulosus serine:threonine protein kinase SMG1 0.002 0.0039 0.0045
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0019 0.0033 0.0055
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0101 0.05 0.0848
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0156 0.0586
Loa Loa (eye worm) fli-1 protein 0.022 0.1179 0.1999
Plasmodium falciparum calcium-dependent protein kinase 4 0.0103 0.0512 0.0635
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0012 0.0012
Loa Loa (eye worm) major facilitator superfamily transporter 0.0047 0.0194 0.0329
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0082 0.0139
Loa Loa (eye worm) hypothetical protein 0.0085 0.041 0.0694
Echinococcus granulosus tachykinin peptides receptor 99D 0.0015 0.0012 0.0014
Echinococcus granulosus 7tm_1 domain containing protein 0.0015 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0073 0.0342 0.0579
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0019 0.0033 0.0319
Entamoeba histolytica protein kinase, putative 0.0103 0.0512 0.2687
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0047 0.0194 0.024
Schistosoma mansoni protein kinase 0.0103 0.0512 0.0599
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Echinococcus multilocularis solute carrier family 22 0.0047 0.0194 0.0194
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0422 0.2338 0.3965
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.1003 0.1175
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.004 0.015
Echinococcus multilocularis neuropeptide receptor A26 0.0015 0.0012 0.0012
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0015 0.0012 0.0014
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0117 0.0595 0.677
Entamoeba histolytica hypothetical protein 0.004 0.0154 0.0805
Trichomonas vaginalis conserved hypothetical protein 0.0336 0.1843 0.6901
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0373 0.4224
Loa Loa (eye worm) hypothetical protein 0.0029 0.0091 0.0153
Onchocerca volvulus 0.0047 0.0194 0.0726
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0012 0.0012
Plasmodium vivax CDK-related protein kinase 6, putative 0.1425 0.8066 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0092 0.0156
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0022 0.0052 0.0271
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0046 0.0078
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0103 0.0512 0.0958
Giardia lamblia Hexose transporter 0.0047 0.0194 0.0864
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0167 0.0877 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.1003 0.1175
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0015 0.0012 0.0044
Echinococcus granulosus glycyl tRNA synthetase 0.0019 0.0033 0.0038
Brugia malayi follicle stimulating hormone receptor 0.1045 0.5896 1
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0028 0.0082 0.0888
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0336 0.1843 0.1843
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0102 0.1114
Loa Loa (eye worm) hypothetical protein 0.005 0.0209 0.0354
Brugia malayi Cytochrome P450 family protein 0.0052 0.0221 0.0373
Echinococcus granulosus serine protein kinase ATM 0.0035 0.0125 0.0146
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Echinococcus granulosus chromobox protein 1 0.0081 0.0388 0.0454
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0046 0.0078
Loa Loa (eye worm) major facilitator superfamily transporter 0.0047 0.0194 0.0329
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Onchocerca volvulus 0.0015 0.0012 0.0044
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0012 0.0014
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0012 0.0012
Schistosoma mansoni lamin 0.0055 0.0237 0.0277
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0046 0.0078
Brugia malayi major facilitator superfamily protein 0.0047 0.0194 0.0329
Onchocerca volvulus 0.0047 0.0194 0.0726
Leishmania major glucose transporter, lmgt1 0.0104 0.052 0.59
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Trypanosoma cruzi hexose transporter, putative 0.0104 0.052 0.59
Onchocerca volvulus 0.0015 0.0012 0.0044
Schistosoma mansoni hypothetical protein 0.0336 0.1843 0.2159
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0095 0.0468 0.0468
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0245 0.0917
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0012 0.0012
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0102 0.0349
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0046 0.0078
Mycobacterium tuberculosis Conserved protein 0.0079 0.0373 0.1323
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Entamoeba histolytica phosphoglycerate kinase, putative 0.0167 0.0877 0.4606
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0194 0.0728
Brugia malayi Heterochromatin protein 1 0.0081 0.0388 0.0657
Schistosoma mansoni cellular tumor antigen P53 0.0108 0.0542 0.0634
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0085 0.041 0.0479
Leishmania major hypothetical protein, conserved 0.0017 0.002 0.0175
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0022 0.0052 0.0542
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Trypanosoma brucei THT1 - hexose transporter, putative 0.0104 0.052 0.59
Onchocerca volvulus 0.0047 0.0194 0.0726
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0022 0.0052 0.0542
Brugia malayi G-protein coupled receptor 0.0015 0.0012 0.002
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0101 0.05 0.0586
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0046 0.0054
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0543 0.3024 0.3749
Leishmania major threonyl-tRNA synthetase, putative 0.0019 0.0033 0.0319
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0064 0.0288 0.1018
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.002 0.0075
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0154 0.0153
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.026 0.0973
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0102 0.019
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0012 0.0012
Onchocerca volvulus 0.0015 0.0012 0.0044
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0274 0.0321
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0012 0.0014
Loa Loa (eye worm) MH2 domain-containing protein 0.0015 0.0013 0.0021
Echinococcus multilocularis mothers against decapentaplegic 5 0.0015 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Brugia malayi Pre-SET motif family protein 0.0061 0.0274 0.0464
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0015 0.0012 0.002
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0019 0.0033 0.0055
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0102 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0186 0.0698
Trichomonas vaginalis set domain proteins, putative 0.0481 0.2671 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0268 0.1457 0.2471
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0144 0.0749 0.8528
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0012 0.0012
Loa Loa (eye worm) MH2 domain-containing protein 0.0227 0.1222 0.2072
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0012 0.0012
Loa Loa (eye worm) phosphatidylinositol 3 0.0069 0.0319 0.054
Giardia lamblia GTOR 0.0069 0.0319 0.1528
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0085 0.041 0.0479
Plasmodium vivax lysine--tRNA ligase, putative 0.0075 0.0353 0.0437
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0012 0.0014
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0012 0.0012
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0136 0.0229
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0101 0.05 0.0586
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0167 0.0877 0.1641
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0127 0.0477
Echinococcus granulosus neuropeptide s receptor 0.0015 0.0012 0.0014
Plasmodium falciparum mitogen-activated protein kinase 2 0.0543 0.3024 0.3749
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0046 0.0054
Brugia malayi putative neuropeptide receptor NPR1 0.0015 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Schistosoma mansoni P2X receptor subunit 0.0188 0.0997 0.1167
Brugia malayi steroid hormone receptor 0.0021 0.0046 0.0078
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0347 0.1904 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0052 0.0064
Plasmodium falciparum lysine--tRNA ligase 0.0075 0.0353 0.0437
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0102 0.0102
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0012 0.0014
Plasmodium falciparum threonine--tRNA ligase 0.0019 0.0033 0.004
Echinococcus granulosus solute carrier family 22 0.0047 0.0194 0.0227
Echinococcus granulosus neuropeptide receptor 0.0015 0.0012 0.0014
Echinococcus multilocularis General substrate transporter 0.0289 0.1573 0.1573
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.026 0.0973
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0019 0.0033 0.0319
Onchocerca volvulus 0.0047 0.0194 0.0726
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Schistosoma mansoni neuropeptide receptor 0.0015 0.0012 0.0014
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0035 0.0127 0.0216
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0297 0.0348
Onchocerca volvulus 0.0057 0.0251 0.0939
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0184 0.0688
Echinococcus granulosus lysyl tRNA synthetase 0.0075 0.0353 0.0413
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0046 0.0046
Entamoeba histolytica hypothetical protein 0.0035 0.0125 0.0655
Onchocerca volvulus 0.0015 0.0012 0.0044
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0019 0.0033 0.006
Plasmodium falciparum calcium-dependent protein kinase 2 0.0103 0.0512 0.0635
Echinococcus granulosus alpha 1A adrenergic receptor 0.0015 0.0012 0.0014
Brugia malayi MH2 domain containing protein 0.0227 0.1222 0.2072
Echinococcus multilocularis serotonin receptor 0.0015 0.0012 0.0012
Giardia lamblia Sugar-proton symporter 0.0047 0.0194 0.0864
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Brugia malayi hypothetical protein 0.0015 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.001 0.001
Onchocerca volvulus 0.004 0.0151 0.0565
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0297 0.0503
Echinococcus multilocularis beta LACTamase domain containing family member 0.0079 0.0373 0.0373
Onchocerca volvulus 0.0079 0.0373 0.1396
Trypanosoma brucei glucose transporter 2A 0.0104 0.052 0.59
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0079 0.0373 0.4224
Brugia malayi FAT domain containing protein 0.0015 0.0013 0.0021
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0103 0.0512 0.0599
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0131 0.0676 0.0675
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.0052 0.0087
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0082 0.0888
Schistosoma mansoni lysyl-tRNA synthetase 0.0075 0.0353 0.0413
Brugia malayi MH1 domain containing protein 0.0015 0.0013 0.0021
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.0052 0.0087
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.004 0.015
Toxoplasma gondii glycyl-tRNA synthetase 0.0019 0.0033 0.006
Loa Loa (eye worm) hypothetical protein 0.0047 0.0194 0.0329
Onchocerca volvulus 0.0015 0.0012 0.0044
Loa Loa (eye worm) hypothetical protein 0.0054 0.0231 0.0392
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0101 0.05 0.5677
Loa Loa (eye worm) hypothetical protein 0.0103 0.0512 0.0868
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0022 0.0081
Echinococcus granulosus fatty acid amide hydrolase 1 0.0073 0.0342 0.04
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0102 0.0172
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0127 0.0477
Loa Loa (eye worm) beta-lactamase 0.0079 0.0373 0.0633
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0082 0.0888
Onchocerca volvulus 0.0047 0.0194 0.0726
Mycobacterium leprae conserved hypothetical protein 0.0079 0.0373 0.4224
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0297 0.0348
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0102 0.0102
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0085 0.041 0.0694
Echinococcus granulosus mothers against decapentaplegic 5 0.0015 0.0013 0.0015
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0035 0.0125 0.0146
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0015 0.0012 0.0014
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0012 0.0014
Echinococcus granulosus allatostatin A receptor 0.0015 0.0012 0.0014
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0015 0.0012 0.0012
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0015 0.0012 0.002
Mycobacterium ulcerans sugar transporter 0.0047 0.0194 0.2173
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0117 0.0595 0.677
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.002 0.0041 0.0076
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.1612 0.6036
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0069 0.0319 0.0373
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0268 0.1457 0.2471
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0099 0.0488 0.2561
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0167 0.0877 0.3132
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0047 0.0194 0.0227
Echinococcus granulosus fmrfamide receptor 0.0015 0.0012 0.0014
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0012 0.002
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0274 0.309
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0103 0.0512 0.0512
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0015 0.0012 0.0014
Trypanosoma brucei glucose transporter, putative 0.0104 0.052 0.59
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0245 0.0917
Trichomonas vaginalis chromobox protein, putative 0.0013 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Trypanosoma brucei THT1 - hexose transporter, putative 0.0104 0.052 0.59
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Loa Loa (eye worm) hypothetical protein 0.0101 0.05 0.0848
Brugia malayi TAR-binding protein 0.0065 0.0297 0.0503
Schistosoma mansoni sugar transporter 0.0047 0.0194 0.0227
Echinococcus multilocularis lamin 0.0055 0.0237 0.0237
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0036 0.0128 0.1412
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0102 0.0102
Brugia malayi MH1 domain containing protein 0.0015 0.0013 0.0021
Brugia malayi G-protein coupled receptor 0.0015 0.0012 0.002
Echinococcus granulosus hypothetical protein 0.0015 0.0012 0.0014
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0117 0.0595 0.677
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0046 0.0054
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0012 0.0014
Brugia malayi hypothetical protein 0.0022 0.005 0.0084
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Plasmodium falciparum phd finger protein, putative 0.0029 0.0091 0.0112
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.001 0.0017
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0373 0.0437
Loa Loa (eye worm) hypothetical protein 0.0028 0.0082 0.0139
Schistosoma mansoni hypothetical protein 0.0015 0.0012 0.0014
Brugia malayi latrophilin 2 splice variant baaae 0.0183 0.0972 0.1648
Giardia lamblia Prolyl-tRNA synthetase 0.0101 0.05 0.2498
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0015 0.0013 0.0015
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0082 0.0139
Loa Loa (eye worm) hypothetical protein 0.0047 0.0194 0.0329
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0295 0.1612 0.6036
Chlamydia trachomatis proline--tRNA ligase 0.0036 0.0128 0.1129
Echinococcus granulosus p2X purinoceptor 4 0.0188 0.0997 0.1167
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.002 0.0041 0.0047
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0046 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0046 0.0078
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.001 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0046 0.0078
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0015 0.0012 0.002
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0015 0.0012 0.002
Toxoplasma gondii DNA methyltransferase 2, putative 0.002 0.0041 0.0076
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0512 0.1917
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0512 0.0599
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0046 0.0054
Onchocerca volvulus 0.0047 0.0194 0.0726
Brugia malayi Doublecortin family protein 0.0022 0.005 0.0084
Plasmodium vivax sugar transporter, putative 0.0047 0.0194 0.024
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0046 0.0046
Mycobacterium tuberculosis Conserved hypothetical protein 0.0017 0.002 0.0055
Echinococcus granulosus General substrate transporter 0.0289 0.1573 0.1843
Loa Loa (eye worm) hypothetical protein 0.0047 0.0194 0.0329
Trypanosoma cruzi target of rapamycin kinase 3 0.0059 0.026 0.2925
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0012 0.0014
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Echinococcus granulosus solute carrier family 22 0.0047 0.0194 0.0227
Echinococcus multilocularis neuropeptide FF receptor 2 0.0015 0.0012 0.0012
Mycobacterium ulcerans esterase/lipase LipP 0.0079 0.0373 0.4224
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0624 0.71
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0078
Onchocerca volvulus Alhambra homolog 0.0029 0.0091 0.0338
Trichomonas vaginalis chromobox protein, putative 0.0013 0 0.0001
Treponema pallidum exodeoxyribonuclease (exoA) 0.0022 0.0052 0.0123
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.0338 0.0395
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0189 0.1003 0.1003
Entamoeba histolytica acyl-coA synthetase, putative 0.0028 0.0082 0.0429
Brugia malayi ecdysteroid receptor 0.0021 0.0046 0.0078
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0189 0.1003 0.1701
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0336 0.1843 0.2159
Echinococcus multilocularis G protein coupled receptor 139 0.0015 0.0012 0.0012
Echinococcus multilocularis Chromobox protein 3 0.0013 0 0.000000014476
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0069 0.0319 0.3597
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0046 0.0054
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0624 0.71
Brugia malayi jmjC domain containing protein 0.0095 0.0468 0.0794
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0064 0.0288 0.1018
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0012 0.0014
Echinococcus granulosus Sugar transporter ERD6 protein 0.0047 0.0194 0.0227
Echinococcus granulosus Smad4 0.0015 0.0013 0.0015
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0015 0.0012 0.002
Brugia malayi acetyltransferase, GNAT family protein 0.0154 0.0806 0.1367
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0035 0.0041
Echinococcus granulosus cytochrome P450 2K1 0.0014 0.0005 0.0005
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0103 0.0512 0.5814
Schistosoma mansoni alpha-1 adrenergic receptor 0.0015 0.0012 0.0014
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0012 0.0012
Schistosoma mansoni rab6-interacting 0.0022 0.005 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.002 0.0075
Schistosoma mansoni histamine h1 receptor 0.0015 0.0012 0.0014
Echinococcus granulosus jumonji domain containing protein 0.004 0.0156 0.0182
Loa Loa (eye worm) hypothetical protein 0.0019 0.0033 0.0055
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0079 0.0373 0.0633
Echinococcus granulosus p2X purinoceptor 4 0.0188 0.0997 0.1167
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0036 0.0112
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0095 0.0468 0.0548
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.002 0.0175
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0035 0.0127 0.1407
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0046 0.0054
Brugia malayi Disco-interacting protein 2 homolog 0.004 0.0151 0.0256
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0033 0.0111 0.1217
Schistosoma mansoni glucose transport protein 0.0336 0.1843 0.2159
Echinococcus granulosus neuropeptide FF receptor 2 0.0015 0.0012 0.0014
Echinococcus multilocularis synaptic vesicle 2 protein 0.0047 0.0194 0.0194
Onchocerca volvulus 0.0013 0 0.000000054208
Schistosoma mansoni hypothetical protein 0.0183 0.0972 0.1139
Echinococcus multilocularis calcium dependent protein kinase 0.0096 0.0476 0.0475
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0127 0.0477
Brugia malayi GnHR receptor homolog 0.0015 0.0012 0.002
Echinococcus granulosus dro:myosuppressin receptor 0.0015 0.0012 0.0014
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0297 0.0503
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0012 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0319 0.1193
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0078
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0015 0.0013 0.0015
Brugia malayi MH2 domain containing protein 0.0015 0.0013 0.0021
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0624 0.0731
Loa Loa (eye worm) hypothetical protein 0.0047 0.0194 0.0329
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0167 0.0877 0.3285
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0019 0.0033 0.0319
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0102 0.0172
Loa Loa (eye worm) acetyltransferase 0.0154 0.0806 0.1367
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0167 0.0877 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.005 0.005
Schistosoma mansoni Smad4 0.0015 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0079 0.0373 0.0633
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0012 0.0014
Echinococcus multilocularis orexin receptor type 2 0.0015 0.0012 0.0012
Brugia malayi hypothetical protein 0.0015 0.0012 0.002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0036 0.0112
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0015 0.0012 0.002
Brugia malayi Sugar transporter family protein 0.0336 0.1843 0.3125
Entamoeba histolytica protein kinase rad3, putative 0.002 0.0039 0.0203
Treponema pallidum fructose-bisphosphate aldolase 0.0295 0.1612 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0091 0.0106
Brugia malayi amidase 0.0073 0.0342 0.0579
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Echinococcus multilocularis peregrin 0.0033 0.0112 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0022 0.0081
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0046 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Loa Loa (eye worm) phosphatidylinositol 3 0.0035 0.0127 0.0216
Mycobacterium tuberculosis Probable lipase LipD 0.0079 0.0373 0.1323
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.029 0.0542
Echinococcus granulosus orexin receptor type 2 0.0015 0.0012 0.0014
Echinococcus multilocularis geminin 0.1118 0.6311 0.6311
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0019 0.0033 0.0055
Toxoplasma gondii protein kinase, putative 0.0949 0.5344 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0258 0.0301
Schistosoma mansoni fatty-acid amide hydrolase 0.0073 0.0342 0.04
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0075 0.0353 0.3989
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0035 0.0127 0.1407
Brugia malayi hypothetical protein 0.0022 0.005 0.0084
Brugia malayi intermediate filament protein 0.0055 0.0237 0.0402
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0274 0.0321
Brugia malayi Major Facilitator Superfamily protein 0.0047 0.0194 0.0329
Schistosoma mansoni hypothetical protein 0.0022 0.005 0.0058
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0154 0.0806 0.0806
Brugia malayi Pre-SET motif family protein 0.0422 0.2338 0.3965
Echinococcus granulosus tar DNA binding protein 0.0065 0.0297 0.0348
Echinococcus multilocularis musashi 0.0055 0.0237 0.0237
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0046 0.0078
Plasmodium vivax acyl-CoA synthetase, putative 0.0021 0.0042 0.0052
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0082 0.0888
Onchocerca volvulus 0.0015 0.0012 0.0044
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0103 0.0512 0.0512
Toxoplasma gondii cytochrome p450 superfamily protein 0.0014 0.0005 0.0008
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0035 0.0127 0.1407
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0012 0.0012
Brugia malayi beta-lactamase family protein 0.0079 0.0373 0.0633
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.026 0.0973
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0101 0.05 0.05
Schistosoma mansoni glucose transporter 0.0047 0.0194 0.0227
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Schistosoma mansoni opsin-like receptor 0.0015 0.0012 0.0014
Echinococcus granulosus g protein coupled receptor 0.0015 0.0012 0.0014
Echinococcus granulosus somatostatin receptor 0.0015 0.0012 0.0014
Schistosoma mansoni hypothetical protein 0.1118 0.6311 0.7393
Brugia malayi SET domain containing protein 0.0016 0.0017 0.0028
Onchocerca volvulus 0.0047 0.0194 0.0726
Trichomonas vaginalis conserved hypothetical protein 0.0171 0.09 0.3371
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.005 0.005
Brugia malayi beta-lactamase 0.0079 0.0373 0.0633
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0189 0.1003 0.1175
Echinococcus multilocularis cpg binding protein 0.0067 0.0306 0.0306
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0012 0.0012
Schistosoma mansoni amidase 0.0073 0.0342 0.04
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0373 0.1398
Schistosoma mansoni lamin 0.0055 0.0237 0.0277
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0046 0.0054
Echinococcus multilocularis chromobox protein 1 0.0081 0.0388 0.0387
Echinococcus multilocularis allatostatin A receptor 0.0015 0.0012 0.0012
Entamoeba histolytica protein kinase, putative 0.0103 0.0512 0.2687
Schistosoma mansoni chromobox protein 0.0081 0.0388 0.0454
Schistosoma mansoni P2X receptor subunit 0.0062 0.0278 0.0325
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0502 0.2791 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0046 0.0078
Schistosoma mansoni lysyl-tRNA synthetase 0.0075 0.0353 0.0413
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0245 0.0917
Brugia malayi glycyl-tRNA synthetase 0.0019 0.0033 0.0055
Trichomonas vaginalis chromobox protein, putative 0.0013 0 0.0001
Brugia malayi nuclear hormone receptor 0.0021 0.0046 0.0078
Brugia malayi hypothetical protein 0.0047 0.0194 0.0329
Entamoeba histolytica hypothetical protein 0.0099 0.0488 0.2561
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0012 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0297 0.0348
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0012 0.0014
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0087 0.0422 0.0523
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0103 0.0512 0.0512
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0237 0.0402
Onchocerca volvulus 0.0036 0.0128 0.0478
Onchocerca volvulus 0.0481 0.2671 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0082 0.0139
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0624 0.0731
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0046 0.0054
Schistosoma mansoni sugar transporter 0.0047 0.0194 0.0227
Onchocerca volvulus 0.0047 0.0194 0.0726
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0045 0.0076
Trypanosoma brucei glucose transporter, putative 0.0104 0.052 0.59
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0061 0.0274 0.309
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0308 0.036
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Onchocerca volvulus 0.0047 0.0194 0.0726
Schistosoma mansoni fkbp-rapamycin associated protein 0.002 0.0039 0.0045
Schistosoma mansoni glucose transport protein 0.0336 0.1843 0.2159
Loa Loa (eye worm) hypothetical protein 0.0026 0.0075 0.0127
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0019 0.0033 0.0319
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0057 0.0251 0.0425
Schistosoma mansoni biogenic amine receptor 0.0015 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0079 0.0373 0.0633
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Schistosoma mansoni microtubule-associated protein tau 0.1507 0.8535 1
Trichomonas vaginalis glucose transporter, putative 0.0047 0.0194 0.0728
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0012 0.0012
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0237 0.0402
Brugia malayi PHD-finger family protein 0.0029 0.0091 0.0153
Brugia malayi Fli-1 protein 0.022 0.1179 0.1999
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0035 0.0127 0.0127
Echinococcus granulosus calcium dependent protein kinase 0.0096 0.0476 0.0557
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0186 0.0697
Schistosoma mansoni lipoxygenase 0.0092 0.045 0.0526
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0624 0.0731
Echinococcus multilocularis sex peptide receptor 0.0015 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0078
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0624 0.1167
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0091 0.0112
Echinococcus granulosus G protein coupled receptor 139 0.0015 0.0012 0.0014
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0022 0.0052 0.0542
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0028 0.0082 0.0278
Echinococcus multilocularis serotonin receptor 0.0015 0.0012 0.0012
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0015 0.0012 0.002
Mycobacterium ulcerans phosphoglycerate kinase 0.0167 0.0877 1
Toxoplasma gondii sugar transporter ST1 0.0047 0.0194 0.0363
Brugia malayi hypothetical protein 0.0015 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Giardia lamblia Lysyl-tRNA synthetase 0.0075 0.0353 0.1711
Treponema pallidum phosphoglycerate kinase 0.0167 0.0877 0.5349
Plasmodium falciparum acyl-CoA synthetase 0.0021 0.0042 0.0052
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0274 0.0274
Schistosoma mansoni myosin xvIII 0.0015 0.0012 0.0014
Schistosoma mansoni hypothetical protein 0.0085 0.041 0.0479
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0052 0.0195
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0319 0.1193
Leishmania major 4-coumarate:coa ligase-like protein 0.0028 0.0082 0.0888
Brugia malayi CHD4 protein 0.0015 0.001 0.0017
Trypanosoma brucei phosphoglycerate kinase 0.0167 0.0877 1
Echinococcus multilocularis 0.0014 0.0005 0.0004
Echinococcus granulosus sex peptide receptor 0.0015 0.0012 0.0014
Giardia lamblia DNA repair protein RAD52 0.0347 0.1904 1
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0184 0.0688
Echinococcus granulosus fatty acid amide hydrolase 1 0.0073 0.0342 0.04
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0046 0.0046
Onchocerca volvulus 0.0047 0.0194 0.0726
Loa Loa (eye worm) transcription factor SMAD2 0.0227 0.1222 0.2072
Echinococcus multilocularis solute carrier family 22 0.0047 0.0194 0.0194
Brugia malayi Dopamine receptor 0.0015 0.0012 0.002
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0046 0.0054
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0162 0.085
Echinococcus multilocularis neuropeptide s receptor 0.0015 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0156 0.0586
Echinococcus granulosus geminin 0.1118 0.6311 0.7393
Schistosoma mansoni ets-related 0.022 0.1179 0.1381
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0046 0.0078
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0267 0.0453
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0336 0.1843 0.2159
Echinococcus multilocularis dro:myosuppressin receptor 0.0015 0.0012 0.0012
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0103 0.0512 0.0635
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0102 0.1114
Brugia malayi Phosphoglycerate kinase 0.0167 0.0877 0.1488
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0 0.0001
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0015 0.0012 0.0014
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0046 0.0078
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0012 0.0012
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0046 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0108 0.0406
Echinococcus granulosus neuropeptide receptor 0.0015 0.0012 0.0014
Brugia malayi isocitrate dehydrogenase 0.0031 0.0102 0.0172
Mycobacterium ulcerans integral membrane transport protein 0.0047 0.0194 0.2173
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0047 0.0194 0.0194
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0274 0.0274
Loa Loa (eye worm) hypothetical protein 0.0047 0.0194 0.0329
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.0338 0.0337
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0079 0.0373 0.1323
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0082 0.0888
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0373 0.1398
Schistosoma mansoni cytochrome P450 0.0014 0.0005 0.0005
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0046 0.0054
Echinococcus granulosus lamin dm0 0.0055 0.0237 0.0277
Brugia malayi Melatonin receptor type 1A 0.0015 0.0012 0.002
Brugia malayi RNA binding protein 0.0065 0.0297 0.0503
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0041 0.0161 0.0272
Echinococcus granulosus lamin 0.0055 0.0237 0.0277
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0167 0.0877 0.3285
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0074 0.035 0.0409
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0136 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.052 0.1945
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.005 0.0062
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0069 0.0319 0.0373
Trypanosoma brucei glucose transporter, putative 0.0104 0.052 0.59
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0194 0.0728
Brugia malayi Cytochrome P450 family protein 0.0014 0.0005 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0194 0.0728
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0064 0.0288 0.325
Loa Loa (eye worm) CXXC zinc finger family protein 0.0065 0.0296 0.0502
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0012 0.0014
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0046 0.0171
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0019 0.0033 0.01
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0274 0.0321
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0012 0.0014
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0046 0.0171
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0012 0.0014
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0103 0.0512 0.0599
Schistosoma mansoni biogenic amine receptor 0.0015 0.0012 0.0014
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0019 0.0033 0.0169
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0075 0.0353 0.1321
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0069 0.0319 0.3597
Onchocerca volvulus 0.0108 0.0542 0.2027
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0012 0.002
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0046 0.0046
Echinococcus granulosus intermediate filament protein 0.0055 0.0237 0.0277
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0015 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0186 0.0697
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0274 0.0321
Trypanosoma cruzi hexose transporter 0.0104 0.052 0.59
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0012 0.0014
Leishmania major hypothetical protein, conserved 0.0047 0.0194 0.2173
Trypanosoma brucei sugar transporter, putative 0.0047 0.0194 0.2173
Plasmodium falciparum phosphoglycerate kinase 0.0167 0.0877 0.1087
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0012 0.0014
Onchocerca volvulus 0.0015 0.0012 0.0044
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0162 0.0693
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0012 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0245 0.0917
Echinococcus multilocularis solute carrier family 22 0.0047 0.0194 0.0194
Echinococcus granulosus phosphoglycerate kinase 1 0.0167 0.0877 0.1027
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Brugia malayi Ets-domain containing protein 0.0072 0.0338 0.0572
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0373 0.4224
Entamoeba histolytica acyl-CoA synthetase, putative 0.0028 0.0082 0.0429
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.002 0.0075
Trichomonas vaginalis myo-inositol transporter, putative 0.0047 0.0194 0.0728
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0194 0.0728
Onchocerca volvulus 0.0015 0.0012 0.0044
Schistosoma mansoni growth hormone secretagogue receptor 0.0015 0.0012 0.0014
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0103 0.0512 0.0599
Brugia malayi Cytochrome P450 family protein 0.0014 0.0005 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0184 0.0689
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0184 0.0343
Echinococcus granulosus neuropeptide receptor A26 0.0015 0.0012 0.0014
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0028 0.0082 0.0888
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0073 0.0342 0.0342
Echinococcus multilocularis DNA methyltransferase 2, putative 0.002 0.0041 0.004
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0 0.0001
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0268 0.1457 0.2471
Brugia malayi putative neuropeptide receptor 0.0015 0.0012 0.002
Onchocerca volvulus 0.0055 0.0237 0.0887
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.026 0.0973
Loa Loa (eye worm) sugar transporter 0.0047 0.0194 0.0329
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0046 0.0078
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0019 0.0033 0.0055
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0028 0.0086 0.0933
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.002
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0373 0.1398
Loa Loa (eye worm) hypothetical protein 0.0047 0.0194 0.0329
Schistosoma mansoni opsin-like receptor 0.0015 0.0012 0.0014
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.0338 0.0572
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0194 0.0728
Brugia malayi beta-lactamase family protein 0.0079 0.0373 0.0633
Schistosoma mansoni smad1 5 8 and 0.0015 0.0013 0.0015
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0103 0.0512 0.0635
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0027 0.0081 0.0876
Loa Loa (eye worm) hypothetical protein 0.028 0.1525 0.2587
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.0052 0.006
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.0052 0.0542
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0012 0.0012
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0624 0.2224
Echinococcus granulosus chromobox protein 1 0.0081 0.0388 0.0454
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0336 0.1843 0.1843
Brugia malayi hypothetical protein 0.0047 0.0194 0.0329
Brugia malayi Serotonin receptor 0.0015 0.0012 0.002
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0075 0.0353 0.3989
Trichomonas vaginalis esterase, putative 0.0079 0.0373 0.1398
Loa Loa (eye worm) hypothetical protein 0.0022 0.005 0.0084
Schistosoma mansoni protein kinase 0.0103 0.0512 0.0599
Brugia malayi nuclear receptor NHR-88 0.0021 0.0046 0.0078
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0012 0.0012
Plasmodium falciparum proline--tRNA ligase 0.0117 0.0595 0.0738
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0 0.0001
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.0052 0.0052
Echinococcus multilocularis tumor protein p63 0.0738 0.4141 0.4141
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.002 0.0041 0.0212
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0046 0.0054
Echinococcus granulosus DNA methyltransferase 2, putative 0.002 0.0041 0.0047
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0022 0.0052 0.023
Schistosoma mansoni biogenic amine receptor 0.0015 0.0012 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0245 0.0917
Onchocerca volvulus 0.0047 0.0194 0.0726
Schistosoma mansoni cpg binding protein 0.0065 0.0296 0.0347
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.002 0.0039 0.0203
Brugia malayi hypothetical protein 0.0015 0.0012 0.002
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.005 0.0058
Onchocerca volvulus 0.0047 0.0194 0.0726
Onchocerca volvulus 0.0047 0.0194 0.0726
Trypanosoma cruzi sugar transporter, putative 0.0047 0.0194 0.2173
Schistosoma mansoni hypothetical protein 0.0085 0.041 0.0479
Echinococcus granulosus peptide allatostatin:somatostatin 0.0015 0.0012 0.0014
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0015 0.0012 0.0014
Schistosoma mansoni amine GPCR 0.0015 0.0012 0.0014

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 30.8 uM Inhibition of aminopeptidase N ChEMBL. 20129718

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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