Detailed information for compound 1126524

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 301.686 | Formula: C10H12ClN5O4
  • H donors: 4 H acceptors: 6 LogP: -0.81 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]1OC([C@@H]([C@@H]1O)O)n1ncc2c1nc(Cl)nc2N
  • InChi: 1S/C10H12ClN5O4/c11-10-14-7(12)3-1-13-16(8(3)15-10)9-6(19)5(18)4(2-17)20-9/h1,4-6,9,17-19H,2H2,(H2,12,14,15)/t4-,5-,6-,9?/m1/s1
  • InChiKey: ASOUJKHDWJZTCE-IAHXAJBFSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0018 0.0018 0.0043
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0145 0.0142
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0032 0.0062 0.0247
Echinococcus multilocularis calcium activated potassium channel 0.0018 0.002 0.0011
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0032 0.0062 0.0243
Leishmania major alpha tubulin 0.0269 0.0781 0.303
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.0184 0.0193
Trichomonas vaginalis tubulin epsilon chain, putative 0.0269 0.0781 0.339
Trypanosoma cruzi tubulin delta chain 0.0063 0.0155 0.0544
Trichomonas vaginalis thymidine kinase, putative 0.0767 0.2295 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0032 0.0062 0.0247
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0032 0.0062 0.0247
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0018 0.0018 0.0009
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0018 0.0018 0.0043
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Echinococcus granulosus voltage gated potassium channel 0.0018 0.0018 0.0043
Plasmodium falciparum protoporphyrinogen oxidase 0.0188 0.0536 0.2112
Plasmodium vivax beta-ketoacyl-acyl carrier protein synthase III precursor, putative 0.0645 0.1925 0.7587
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Brugia malayi Cyclic-nucleotide gated cation channel 0.0018 0.0018 0.0026
Entamoeba histolytica hypothetical protein 0.0074 0.019 0.0712
Echinococcus granulosus Tubulin beta 2C chain 0.0145 0.0404 0.1903
Echinococcus granulosus lysine specific histone demethylase 1A 0.0188 0.0536 0.2539
Loa Loa (eye worm) hypothetical protein 0.0033 0.0064 0.071
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0161 0.1791
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0206 0.059 0.6579
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.002 0.0053
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0032 0.0062 0.0254
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.01 0.0268 0.0992
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0032 0.0062 0.0247
Brugia malayi cation channel family protein 0.0018 0.0018 0.0026
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Schistosoma mansoni cpg binding protein 0.006 0.0145 0.0656
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.0018 0.0043
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0188 0.0536 0.2112
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.3098 0.9386 1
Leishmania major hypothetical protein, conserved 0.0072 0.0184 0.0658
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.267 0.8084 1
Echinococcus multilocularis cpg binding protein 0.0063 0.0155 0.0147
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Trypanosoma cruzi epsilon tubulin, putative 0.0145 0.0404 0.1532
Toxoplasma gondii transporter, cation channel family protein 0.0018 0.0018 0.0071
Echinococcus granulosus ATP binding cassette sub family G 0.003 0.0055 0.0223
Plasmodium falciparum alpha tubulin 2 0.0269 0.0781 0.308
Mycobacterium ulcerans hypothetical protein 0.0168 0.0474 0.0521
Entamoeba histolytica P-glycoprotein-5 0.0032 0.0062 0.0147
Loa Loa (eye worm) deoxynucleoside kinase 0.0074 0.019 0.2114
Brugia malayi MH2 domain containing protein 0.0119 0.0325 0.0478
Trypanosoma cruzi UDP-galactopyranose mutase 0.0188 0.0536 0.2056
Echinococcus granulosus two pore calcium channel protein 2 0.0018 0.0018 0.0043
Trichomonas vaginalis tubulin beta chain, putative 0.0269 0.0781 0.339
Echinococcus multilocularis sodium channel protein 0.0018 0.0018 0.0009
Loa Loa (eye worm) hypothetical protein 0.0032 0.0062 0.0688
Echinococcus multilocularis protoporphyrinogen oxidase 0.0188 0.0536 0.0527
Loa Loa (eye worm) hypothetical protein 0.0188 0.0536 0.5971
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0151 0.0422 0.1604
Leishmania major zeta tubulin, putative 0.0063 0.0155 0.0544
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0018 0.0018 0.0043
Echinococcus multilocularis Tubulin alpha 1 chain 0.0269 0.0781 0.0773
Echinococcus granulosus tubulin alpha 1C chain 0.0269 0.0781 0.3722
Entamoeba histolytica hypothetical protein 0.0074 0.019 0.0712
Trypanosoma brucei thymidine kinase 0.0767 0.2295 0.9037
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0645 0.1925 1
Brugia malayi tubulin alpha-2 chain 0.0269 0.0781 0.1147
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0084 0.0218 0.243
Mycobacterium ulcerans hypothetical protein 0.0072 0.0184 0.016
Echinococcus granulosus ryanodine receptor 44f 0.0018 0.0018 0.0043
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.002 0.0011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Onchocerca volvulus 0.006 0.0145 0.0155
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.0018 0.0043
Schistosoma mansoni tyrosine kinase 0.0162 0.0456 0.2155
Trichomonas vaginalis tubulin epsilon chain, putative 0.0145 0.0404 0.1742
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0032 0.0062 0.0247
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0188 0.0536 0.0527
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.01 0.0268 0.2986
Schistosoma mansoni smdr2 0.0032 0.0062 0.0254
Leishmania major alpha tubulin 0.0269 0.0781 0.303
Entamoeba histolytica tubulin alpha chain, putative 0.0269 0.0781 0.3322
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0032 0.0062 0.0247
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0041 0.016
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0161 0.0731
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0161 0.0236
Chlamydia trachomatis protoporphyrinogen oxidase 0.0188 0.0536 0.2545
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0151 0.0422 0.1604
Brugia malayi Tubulin gamma chain 0.0145 0.0404 0.0593
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.0018 0.0043
Schistosoma mansoni voltage-gated cation channel 0.0018 0.0018 0.0043
Trichomonas vaginalis deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.0147 0.0412 0.1779
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Trypanosoma brucei tubulin gamma chain 0.0145 0.0404 0.1532
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0184 0.0658
Loa Loa (eye worm) hypothetical protein 0.0286 0.0835 0.93
Echinococcus multilocularis short transient receptor potential channel 6 0.0079 0.0203 0.0194
Echinococcus granulosus voltage gated potassium channel 0.0018 0.0018 0.0043
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0028 0.0042
Loa Loa (eye worm) tubulin alpha-2 chain 0.0269 0.0781 0.8707
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0126 0.0348 0.1634
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0155 0.0655
Loa Loa (eye worm) hypothetical protein 0.0286 0.0835 0.93
Echinococcus granulosus tubulin alpha chain 0.0269 0.0781 0.3722
Plasmodium vivax ABC transporter G family member 2, putative 0.003 0.0055 0.0218
Entamoeba histolytica deoxycytidine triphosphate deaminase, putative 0.0051 0.012 0.0403
Schistosoma mansoni tyrosinase precursor 0.0286 0.0835 0.3978
Trichomonas vaginalis abcb9, putative 0.0032 0.0062 0.0247
Echinococcus multilocularis thymidine kinase 0.0331 0.0971 0.0963
Loa Loa (eye worm) tubulin alpha chain 0.0269 0.0781 0.8707
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0018 0.0018 0.0026
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0462 0.1367 0.1777
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0164 0.0462 0.2181
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0201 0.0576 0.6416
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0018 0.0018 0.0026
Entamoeba histolytica P-glycoprotein-2 0.0032 0.0062 0.0147
Trichomonas vaginalis tubulin, putative 0.0145 0.0404 0.1742
Brugia malayi SWIRM domain containing protein 0.0188 0.0536 0.0787
Entamoeba histolytica hypothetical protein 0.017 0.0482 0.2003
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.0184 0.0175
Loa Loa (eye worm) ShTK domain-containing protein 0.0286 0.0835 0.93
Toxoplasma gondii hypothetical protein 0.0018 0.0018 0.0071
Echinococcus multilocularis cyclin dependent kinase 9 0.0056 0.0134 0.0125
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0018 0.0018 0.0043
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0325 0.3624
Loa Loa (eye worm) hypothetical protein 0.0188 0.0536 0.5971
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0032 0.0062 0.0053
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.0018 0.0009
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0018 0.0018 0.0009
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0032 0.0062 0.0247
Onchocerca volvulus 0.0032 0.0062 0.0066
Brugia malayi RNA, U transporter 1 0.0082 0.0213 0.0312
Echinococcus multilocularis Tubulin beta 2C chain 0.0145 0.0404 0.0395
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0318 0.0932 0.3627
Trypanosoma brucei alpha tubulin 0.0269 0.0781 0.303
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0109 0.0483
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0645 0.1925 0.2329
Loa Loa (eye worm) hypothetical protein 0.0029 0.0052 0.0574
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0161 0.0731
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0268 0.1248
Entamoeba histolytica hypothetical protein 0.0051 0.012 0.0403
Trypanosoma brucei tubulin delta chain 0.0063 0.0155 0.0544
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Schistosoma mansoni patched 1 0.0084 0.0218 0.1007
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0145 0.0657
Trypanosoma brucei epsilon tubulin 0.0145 0.0404 0.1532
Toxoplasma gondii RNA-directed DNA polymerase 0.0846 0.2538 1
Entamoeba histolytica tubulin gamma chain 0.0145 0.0404 0.1657
Plasmodium falciparum tubulin epsilon chain, putative 0.0145 0.0404 0.1592
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0286 0.0835 0.1225
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0145 0.0112
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.01 0.0326
Echinococcus granulosus beta tubulin 0.0145 0.0404 0.1903
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.0018 0.0043
Brugia malayi CXXC zinc finger family protein 0.006 0.0145 0.0213
Giardia lamblia Beta tubulin 0.0145 0.0404 0.1497
Brugia malayi Tubulin alpha chain 0.0269 0.0781 0.1147
Schistosoma mansoni hypothetical protein 0.0018 0.0018 0.0043
Schistosoma mansoni kinase 0.0048 0.0109 0.0483
Echinococcus granulosus Tubulin beta 2C chain 0.0145 0.0404 0.1903
Trichomonas vaginalis tubulin beta chain, putative 0.0269 0.0781 0.339
Onchocerca volvulus 0.0286 0.0835 0.0889
Trichomonas vaginalis tubulin alpha chain, putative 0.0145 0.0404 0.1742
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.0018 0.0043
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0032 0.0062 0.003
Echinococcus granulosus peroxisome assembly protein 26 0.0269 0.0781 0.3722
Onchocerca volvulus 0.0018 0.0018 0.0019
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0188 0.0536 0.0599
Trypanosoma brucei telomerase reverse transcriptase 0.0846 0.2538 1
Loa Loa (eye worm) voltage-dependent calcium channel 0.0018 0.0018 0.02
Plasmodium falciparum ABC transporter G family member 2 0.003 0.0055 0.0218
Loa Loa (eye worm) multidrug resistance protein 3 0.0032 0.0062 0.0688
Echinococcus multilocularis tubulin delta chain 0.0063 0.0155 0.0146
Giardia lamblia Telomerase catalytic subunit 0.0846 0.2538 1
Loa Loa (eye worm) beta-lactamase 0.0072 0.0184 0.2047
Loa Loa (eye worm) kinesin-like protein KLP2 0.0027 0.0045 0.05
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0293 0.1258
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0145 0.0112
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0018 0.0018 0.0043
Leishmania major alpha tubulin 0.0269 0.0781 0.303
Giardia lamblia Gamma tubulin 0.0145 0.0404 0.1497
Echinococcus granulosus tubulin epsilon chain 0.0145 0.0404 0.1903
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.0018 0.0043
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0055 0.013 0.0444
Loa Loa (eye worm) hypothetical protein 0.0188 0.0536 0.5971
Loa Loa (eye worm) hypothetical protein 0.0204 0.0586 0.6525
Schistosoma mansoni amine oxidase 0.0188 0.0536 0.2539
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0032 0.0062 0.0247
Leishmania major epsilon tubulin, putative 0.0145 0.0404 0.1532
Brugia malayi TAR-binding protein 0.0201 0.0576 0.0845
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0222 0.0638 0.269
Trichomonas vaginalis ABC transporter, putative 0.0032 0.0062 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.019 0.0806
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0032 0.0062 0.0247
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Trypanosoma brucei alpha tubulin 0.0269 0.0781 0.303
Trypanosoma brucei epsilon tubulin 0.0145 0.0404 0.1532
Echinococcus granulosus expressed conserved protein 0.0183 0.052 0.2462
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0161 0.0236
Leishmania major alpha tubulin 0.0269 0.0781 0.303
Giardia lamblia Hypothetical protein 0.0074 0.019 0.0643
Giardia lamblia ABC transporter 0.0029 0.0053 0.0099
Echinococcus granulosus neuropeptide receptor A26 0.047 0.1395 0.6676
Mycobacterium ulcerans lipase LipD 0.0072 0.0184 0.016
Schistosoma mansoni deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0147 0.0412 0.1944
Leishmania major gamma-tubulin 0.0145 0.0404 0.1532
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Toxoplasma gondii histone lysine-specific demethylase 0.0188 0.0536 0.2112
Trichomonas vaginalis tubulin gamma chain, putative 0.0063 0.0155 0.0655
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0018 0.0018 0.0043
Schistosoma mansoni ABC transporter 0.0025 0.0042 0.0157
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Entamoeba histolytica hypothetical protein 0.0074 0.019 0.0712
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0204 0.0586 0.086
Mycobacterium tuberculosis Conserved hypothetical protein 0.0168 0.0474 0.0581
Brugia malayi hypothetical protein 0.0025 0.0041 0.006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0222 0.0638 0.269
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0018 0.0018 0.0026
Onchocerca volvulus 0.0072 0.0184 0.0196
Trypanosoma cruzi thymidine kinase, putative 0.0767 0.2295 0.9037
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Loa Loa (eye worm) voltage-gated potassium channel 0.0018 0.0018 0.02
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0082 0.0213 0.0908
Entamoeba histolytica hypothetical protein 0.0147 0.0412 0.1694
Brugia malayi voltage-dependent calcium channel 0.0018 0.0018 0.0026
Mycobacterium ulcerans monoamine oxidase 0.0188 0.0536 0.0599
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0018 0.0018 0.0043
Brugia malayi Calcitonin receptor-like protein seb-1 0.0204 0.0586 0.086
Schistosoma mansoni tubulin subunit alpha 0.0269 0.0781 0.3722
Toxoplasma gondii beta-1 tubulin, putative 0.0145 0.0404 0.1592
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0019 0.0028
Echinococcus multilocularis tubulin alpha 1C chain 0.0269 0.0781 0.0773
Echinococcus granulosus sodium channel protein 0.0018 0.0018 0.0043
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor, putative 0.0147 0.0412 0.1694
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Schistosoma mansoni tubulin subunit epsilon 0.0145 0.0404 0.1903
Brugia malayi hypothetical protein 0.0188 0.0536 0.0787
Echinococcus multilocularis protein dispatched 1 0.0095 0.0254 0.0245
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0184 0.078
Echinococcus granulosus beta tubulin 0.0145 0.0404 0.1903
Wolbachia endosymbiont of Brugia malayi dUTPase 0.0147 0.0412 0.1621
Plasmodium vivax tubulin alpha chain, putative 0.0269 0.0781 0.308
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0184 0.0724
Giardia lamblia Hypothetical protein 0.0074 0.019 0.0643
Echinococcus multilocularis thymidine kinase 0.0331 0.0971 0.0963
Mycobacterium tuberculosis Conserved protein 0.0072 0.0184 0.0193
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0033 0.0024
Echinococcus granulosus tar DNA binding protein 0.0201 0.0576 0.2731
Giardia lamblia Deoxyguanosine kinase/deoxyadenosine kinase subunit, putative 0.0074 0.019 0.0643
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0033 0.0113
Echinococcus granulosus tubulin alpha chain 0.0269 0.0781 0.3722
Echinococcus multilocularis tubulin alpha 1C chain 0.0269 0.0781 0.0773
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0032 0.0062 0.0688
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0032 0.0062 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.019 0.0806
Brugia malayi tubulin alpha chain - mouse 0.0269 0.0781 0.1147
Echinococcus granulosus multidrug resistance protein 1 0.0032 0.0062 0.0254
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0145 0.0404 0.0395
Entamoeba histolytica fatty acid elongase, putative 0.0084 0.0219 0.084
Brugia malayi Deoxynucleoside kinase family protein 0.0074 0.019 0.0279
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0018 0.0018 0.0043
Mycobacterium ulcerans cell division protein FtsZ 0.0063 0.0155 0.0124
Echinococcus multilocularis ATP binding cassette sub family G 0.003 0.0055 0.0046
Trichomonas vaginalis tubulin epsilon chain, putative 0.0063 0.0155 0.0655
Schistosoma mansoni tubulin subunit beta 0.0145 0.0404 0.1903
Giardia lamblia Kinesin-5 0.0027 0.0045 0.0065
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0018 0.0018 0.02
Loa Loa (eye worm) alpha-tubulin 0.0269 0.0781 0.8707
Echinococcus multilocularis two pore calcium channel protein 2 0.0018 0.0018 0.0009
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0018 0.0018 0.0043
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0115 0.048
Entamoeba histolytica fatty acid elongase, putative 0.0084 0.0219 0.084
Trichomonas vaginalis tubulin alpha chain, putative 0.0145 0.0404 0.1742
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0035 0.0131
Loa Loa (eye worm) hypothetical protein 0.0032 0.0062 0.0688
Schistosoma mansoni kinase 0.0051 0.0119 0.053
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0188 0.0536 0.2539
Plasmodium vivax deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.0147 0.0412 0.1625
Brugia malayi RNA binding protein 0.0201 0.0576 0.0845
Trichomonas vaginalis tubulin beta chain, putative 0.0269 0.0781 0.339
Mycobacterium tuberculosis Conserved protein 0.0072 0.0184 0.0193
Mycobacterium ulcerans deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0051 0.012 0.008
Echinococcus multilocularis 0.0094 0.0251 0.0242
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.0018 0.0009
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.267 0.8084 1
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0268 0.1148
Echinococcus granulosus ATP binding cassette sub family G 0.003 0.0055 0.0223
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0018 0.0018 0.0026
Toxoplasma gondii hypothetical protein 0.0018 0.0018 0.0071
Loa Loa (eye worm) ABC transporter 0.0025 0.0042 0.0464
Echinococcus granulosus thymidine kinase 0.0331 0.0971 0.4637
Echinococcus multilocularis tubulin alpha chain 0.0269 0.0781 0.0773
Schistosoma mansoni hypothetical protein 0.0697 0.2085 1
Giardia lamblia Epsilon tubulin 0.0063 0.0155 0.0505
Schistosoma mansoni tubulin subunit gamma 0.0145 0.0404 0.1903
Plasmodium vivax tubulin beta chain, putative 0.0145 0.0404 0.1592
Echinococcus multilocularis tubulin alpha chain 0.0269 0.0781 0.0773
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.0018 0.0043
Echinococcus multilocularis potassium large conductance calcium activated 0.0018 0.0018 0.0009
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0032 0.0062 0.0254
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0018 0.0018 0.0009
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0032 0.0062 0.0174
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0145 0.0136
Echinococcus granulosus tubulin beta 4A class IVa 0.0145 0.0404 0.1903
Trichomonas vaginalis thymidine kinase, putative 0.0767 0.2295 1
Schistosoma mansoni hypothetical protein 0.0065 0.0161 0.0731
Echinococcus granulosus GPCR family 2 0.0065 0.0161 0.0731
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Brugia malayi Cell division protein ftsZ 0.0063 0.0155 0.0228
Loa Loa (eye worm) hypothetical protein 0.0269 0.0781 0.8707
Toxoplasma gondii transporter, cation channel family protein 0.0018 0.0018 0.0071
Loa Loa (eye worm) RNA binding protein 0.0201 0.0576 0.6416
Echinococcus multilocularis shaker cognate 0.0018 0.0018 0.0009
Loa Loa (eye worm) tubulin beta chain 0.0063 0.0155 0.1728
Echinococcus multilocularis cyclin dependent kinase 9 0.0048 0.0109 0.01
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0198 0.0565 0.2679
Echinococcus granulosus tubulin alpha 0.0145 0.0404 0.1903
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0041 0.009
Schistosoma mansoni tyrosine kinase 0.0164 0.0462 0.2181
Trypanosoma brucei zeta tubulin, putative 0.0063 0.0155 0.0544
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.0018 0.0043
Loa Loa (eye worm) hypothetical protein 0.0072 0.0184 0.2047
Echinococcus granulosus short transient receptor potential channel 6 0.0079 0.0203 0.0933
Loa Loa (eye worm) hypothetical protein 0.0206 0.059 0.6579
Brugia malayi multidrug resistance protein 3 0.0032 0.0062 0.0091
Mycobacterium ulcerans oxidoreductase 0.0188 0.0536 0.0599
Brugia malayi Importin beta-1 subunit 0.0029 0.0052 0.0076
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0032 0.0062 0.0247
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0161 0.0152
Brugia malayi olfactory channel protein osm-9 0.0018 0.0018 0.0026
Echinococcus granulosus Tubulin beta 2C chain 0.0145 0.0404 0.1903
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0032 0.0062 0.0053
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0032 0.0062 0.0247
Trichomonas vaginalis tubulin beta chain, putative 0.0145 0.0404 0.1742
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0063 0.0155 0.0611
Echinococcus multilocularis tubulin alpha 0.0145 0.0404 0.0395
Leishmania major delta tubulin, putative 0.0063 0.0155 0.0544
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.019 0.0806
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.019 0.0806
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0018 0.0018 0.0009
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0032 0.0062 0.0247
Echinococcus granulosus Tubulin beta 2C chain 0.0145 0.0404 0.1903
Entamoeba histolytica hypothetical protein 0.0023 0.0035 0.0029
Trypanosoma cruzi tubulin delta chain 0.0063 0.0155 0.0544
Brugia malayi amine oxidase, flavin-containing family protein 0.0188 0.0536 0.0787
Trypanosoma cruzi zeta tubulin, putative 0.0063 0.0155 0.0544
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor, putative 0.0147 0.0412 0.1694
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.0018 0.0043
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0325 0.3624
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0063 0.0155 0.0611
Entamoeba histolytica protein kinase domain containing protein 0.0048 0.0109 0.0356
Loa Loa (eye worm) hypothetical protein 0.0025 0.0041 0.0452
Trichomonas vaginalis tubulin, putative 0.0082 0.0213 0.0908
Schistosoma mansoni tubulin subunit beta 0.0063 0.0155 0.0704
Trichomonas vaginalis tubulin gamma chain, putative 0.0145 0.0404 0.1742
Echinococcus granulosus tubulin alpha 3 chain 0.0269 0.0781 0.3722
Schistosoma mansoni NADH-ubiquinone oxidoreductase 0.0074 0.019 0.0871
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0041 0.009
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.0018 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.019 0.0806
Entamoeba histolytica serine/threonine protein kinase, putative 0.01 0.0268 0.1057
Brugia malayi CHE-14 protein 0.0084 0.0218 0.032
Trypanosoma brucei beta tubulin 0.0145 0.0404 0.1532
Echinococcus granulosus Tubulin beta 2C chain 0.0145 0.0404 0.1903
Brugia malayi alpha-tubulin 0.0269 0.0781 0.1147
Echinococcus multilocularis voltage gated potassium channel 0.0018 0.0018 0.0009
Echinococcus multilocularis transfer RNA-Gly 0.0018 0.0018 0.0009
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0018 0.0018 0.0026
Echinococcus granulosus cyclin dependent kinase 9 0.0048 0.0109 0.0483
Entamoeba histolytica P-glycoprotein-2 0.0032 0.0062 0.0147
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0018 0.0018 0.0043
Echinococcus multilocularis hyperpolarization activated cyclic 0.0018 0.0018 0.0009
Schistosoma mansoni tubulin subunit delta 0.0063 0.0155 0.0704
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0028 0.0317
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0032 0.0062 0.0247
Leishmania major GTP-binding protein, putative 0.0021 0.0028 0.0042
Echinococcus granulosus hypothetical protein 0.0018 0.0018 0.0043
Echinococcus multilocularis expressed conserved protein 0.0183 0.052 0.0512
Echinococcus granulosus Thymidine kinase 2 mitochondrial 0.0331 0.0971 0.4637
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0033 0.012
Echinococcus granulosus dUTP pyrophosphatase 0.0147 0.0412 0.1944
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0032 0.0062 0.0247
Entamoeba histolytica tubulin family protein 0.0145 0.0404 0.1657
Loa Loa (eye worm) hypothetical protein 0.0111 0.0302 0.337
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Schistosoma mansoni transient receptor potential channel 0.0079 0.0203 0.0933
Entamoeba histolytica P-glycoprotein 5, putative 0.0032 0.0062 0.0147
Plasmodium falciparum importin beta, putative 0.0029 0.0052 0.0203
Echinococcus granulosus epidermal growth factor receptor 0.0164 0.0462 0.2181
Schistosoma mansoni tyrosine kinase 0.0162 0.0456 0.2155
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0268 0.1148
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0196 0.056 0.2653
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0028 0.0019
Echinococcus multilocularis ATP binding cassette sub family G 0.003 0.0055 0.0046
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0032 0.0062 0.0243
Schistosoma mansoni tubulin subunit beta 0.0145 0.0404 0.1903
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0187 0.0533 0.2303
Trichomonas vaginalis tubulin alpha chain, putative 0.0082 0.0213 0.0908
Loa Loa (eye worm) ion channel NompC 0.0018 0.0018 0.02
Mycobacterium ulcerans beta-lactamase 0.0072 0.0184 0.016
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0184 0.0658
Mycobacterium leprae cell division protein FtsZ 0.0063 0.0155 0.0849
Toxoplasma gondii hypothetical protein 0.0051 0.012 0.0474
Echinococcus granulosus Protein patched homolog 1 0.0084 0.0218 0.1007
Plasmodium falciparum beta-ketoacyl-ACP synthase III 0.0645 0.1925 0.7587
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0028 0.0112
Leishmania major p-glycoprotein 0.0032 0.0062 0.0174
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.003 0.0055 0.0223
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Onchocerca volvulus 0.0072 0.0184 0.0196
Echinococcus granulosus potassium large conductance calcium activated 0.0018 0.0018 0.0043
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0145 0.0573
Trypanosoma cruzi beta tubulin, putative 0.0145 0.0404 0.1532
Onchocerca volvulus Serine\/threonine kinase homolog 0.01 0.0268 0.0286
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Schistosoma mansoni tyrosine kinase 0.0097 0.026 0.1209
Echinococcus multilocularis hyperpolarization activated cyclic 0.0018 0.0018 0.0009
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0048 0.0109 0.1217
Leishmania major alpha tubulin 0.0269 0.0781 0.303
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Loa Loa (eye worm) beta-tubulin 0.0145 0.0404 0.4501
Brugia malayi Tubulin beta chain 0.0063 0.0155 0.0228
Loa Loa (eye worm) voltage-gated calcium channel 0.0018 0.0018 0.02
Echinococcus granulosus sterol regulatory element binding protein 0.0084 0.0218 0.1007
Leishmania major telomerase reverse transcriptase, putative 0.0846 0.2538 1
Echinococcus granulosus alpha tubulin 0.0269 0.0781 0.3722
Plasmodium vivax hypothetical protein, conserved 0.0188 0.0536 0.2112
Leishmania major alpha tubulin 0.0269 0.0781 0.303
Echinococcus multilocularis dUTP pyrophosphatase 0.0147 0.0412 0.0404
Trypanosoma cruzi ABC transporter, putative 0.003 0.0055 0.0148
Echinococcus multilocularis dnaJ subfamily B 0.0405 0.1195 0.1187
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0018 0.0018 0.0026
Mycobacterium tuberculosis Cell division protein FtsZ 0.0063 0.0155 0.0155
Mycobacterium tuberculosis Probable deoxycytidine triphosphate deaminase Dcd (dCTP deaminase) 0.0051 0.012 0.0107
Brugia malayi Tubulin alpha-2 chain 0.0269 0.0781 0.1147
Loa Loa (eye worm) tubulin beta-1 chain 0.0145 0.0404 0.4501
Trichomonas vaginalis ran, putative 0.0021 0.0028 0.0102
Schistosoma mansoni calcium-activated potassium channel 0.0018 0.0018 0.0043
Schistosoma mansoni ryanodine receptor related 0.0018 0.0018 0.0043
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Echinococcus granulosus geminin 0.0697 0.2085 1
Loa Loa (eye worm) hypothetical protein 0.0188 0.0536 0.5971
Echinococcus multilocularis beta tubulin 0.0145 0.0404 0.0395
Loa Loa (eye worm) hypothetical protein 0.0031 0.006 0.0665
Plasmodium falciparum alpha tubulin 1 0.0269 0.0781 0.308
Echinococcus multilocularis Tubulin beta 2C chain 0.0145 0.0404 0.0395
Onchocerca volvulus 0.0072 0.0184 0.0196
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0018 0.0018 0.0009
Echinococcus granulosus serine:threonine protein kinase PLK1 0.01 0.0268 0.1248
Plasmodium vivax tubulin epsilon chain, putative 0.0145 0.0404 0.1592
Schistosoma mansoni hypothetical protein 0.0065 0.0161 0.0731
Echinococcus granulosus cpg binding protein 0.0063 0.0155 0.0705
Loa Loa (eye worm) tubulin beta-2A chain 0.0145 0.0404 0.4501
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Toxoplasma gondii transporter, cation channel family protein 0.0018 0.0018 0.0071
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.0018 0.0043
Trichomonas vaginalis taga, putative 0.0032 0.0062 0.0247
Schistosoma mansoni tubulin subunit alpha 0.0063 0.0155 0.0704
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0286 0.0835 0.1225
Trypanosoma brucei alpha tubulin 0.0269 0.0781 0.303
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0206 0.059 0.2556
Loa Loa (eye worm) tubulin beta-4 chain 0.0145 0.0404 0.4501
Leishmania major alpha tubulin 0.0269 0.0781 0.303
Echinococcus multilocularis conserved hypothetical protein 0.0018 0.0018 0.0009
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0184 0.078
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.0018 0.0043
Entamoeba histolytica hypothetical protein 0.0074 0.019 0.0712
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0052 0.0133
Loa Loa (eye worm) hypothetical protein 0.0102 0.0275 0.3067
Plasmodium vivax tubulin gamma chain, putative 0.0145 0.0404 0.1592
Loa Loa (eye worm) ryanodine receptor 0.0018 0.0018 0.02
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.0184 0.016
Schistosoma mansoni tar DNA-binding protein 0.0201 0.0576 0.2731
Echinococcus multilocularis voltage dependent calcium channel 0.0018 0.0018 0.0009
Brugia malayi Protein kinase domain containing protein 0.0097 0.026 0.0382
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.056 0.2653
Schistosoma mansoni tyrosine kinase 0.0162 0.0456 0.2155
Trichomonas vaginalis abcb9, putative 0.0032 0.0062 0.0247
Trichomonas vaginalis tubulin beta chain, putative 0.0082 0.0213 0.0908
Trypanosoma cruzi epsilon tubulin, putative 0.0145 0.0404 0.1532
Schistosoma mansoni hypothetical protein 0.0081 0.0209 0.0963
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Echinococcus granulosus ATP binding cassette sub family G 0.003 0.0055 0.0223
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0269 0.0781 0.339
Entamoeba histolytica P-glycoprotein-1 0.0032 0.0062 0.0147
Echinococcus multilocularis 0.0188 0.0536 0.0527
Leishmania major alpha tubulin 0.0269 0.0781 0.303
Onchocerca volvulus 0.0082 0.0213 0.0227
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0268 0.1148
Echinococcus granulosus calcium activated potassium channel 0.0018 0.002 0.0052
Schistosoma mansoni hypothetical protein 0.0081 0.0209 0.0963
Trichomonas vaginalis tubulin beta chain, putative 0.0269 0.0781 0.339
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Loa Loa (eye worm) TAR-binding protein 0.0201 0.0576 0.6416
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0145 0.0657
Echinococcus multilocularis Niemann Pick C1 protein 0.0278 0.081 0.0802
Schistosoma mansoni tyrosine kinase 0.0097 0.026 0.1209
Echinococcus multilocularis snurportin 1 0.0307 0.0898 0.0889
Loa Loa (eye worm) hypothetical protein 0.0072 0.0184 0.2047
Toxoplasma gondii ABC1 family protein 0.0072 0.0184 0.0724
Loa Loa (eye worm) tubulin gamma chain 0.0145 0.0404 0.4501
Loa Loa (eye worm) voltage-gated potassium channel 0.0018 0.0018 0.02
Trypanosoma brucei beta tubulin 0.0145 0.0404 0.1532
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Brugia malayi Niemann-Pick C1 protein precursor 0.0195 0.0556 0.0816
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0018 0.0018 0.0026
Echinococcus multilocularis voltage gated potassium channel 0.0018 0.0018 0.0009
Echinococcus multilocularis short transient receptor potential channel 6 0.0079 0.0203 0.0194
Echinococcus multilocularis ryanodine receptor 44f 0.0018 0.0018 0.0009
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0018 0.0018 0.0026
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0032 0.0062 0.0247
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0204 0.0586 0.6525
Brugia malayi hypothetical protein 0.0018 0.0018 0.0026
Brugia malayi ion channel NompC 0.0018 0.0018 0.0026
Trichomonas vaginalis tubulin, putative 0.0063 0.0155 0.0655
Schistosoma mansoni alpha tubulin 0.0269 0.0781 0.3722
Brugia malayi Common central domain of tyrosinase family protein 0.0286 0.0835 0.1225
Plasmodium vivax delta tubulin, putative 0.0063 0.0155 0.0611
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.0018 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0115 0.048
Toxoplasma gondii beta-tubulin, putative 0.0145 0.0404 0.1592
Echinococcus granulosus cyclin dependent kinase 9 0.0056 0.0134 0.0604
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0018 0.0018 0.0043
Entamoeba histolytica fatty acid elongase, putative 0.0084 0.0219 0.084
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.0184 0.2047
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0018 0.0018 0.0043
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0052 0.0203
Trichomonas vaginalis tubulin beta chain, putative 0.0269 0.0781 0.339
Trichomonas vaginalis tubulin beta chain, putative 0.0269 0.0781 0.339
Entamoeba histolytica hypothetical protein 0.0147 0.0412 0.1694
Trypanosoma brucei polo-like protein kinase 0.01 0.0268 0.0992
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0155 0.0655
Toxoplasma gondii deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.0147 0.0412 0.1625
Echinococcus granulosus NADH ubiquinone oxidoreductase 42 kDa subunit 0.0074 0.019 0.0871
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0035 0.0131
Echinococcus multilocularis Tubulin beta 2C chain 0.0145 0.0404 0.0395
Echinococcus granulosus Tubulin alpha 1 chain 0.0269 0.0781 0.3722
Trypanosoma brucei alpha tubulin, putative 0.0082 0.0213 0.0774
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0063 0.0155 0.0196
Trichomonas vaginalis tubulin gamma chain, putative 0.0145 0.0404 0.1742
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0018 0.0018 0.0009
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0018 0.0018 0.0043
Loa Loa (eye worm) BEN-1 protein 0.0145 0.0404 0.4501
Entamoeba histolytica hypothetical protein 0.0074 0.019 0.0712
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0222 0.0638 0.269
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0018 0.0018 0.0043
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.0018 0.0009
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0032 0.0062 0.0247
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0184 0.1538
Trypanosoma cruzi zeta tubulin, putative 0.0063 0.0155 0.0544
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0032 0.0062 0.0247
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0307 0.0898 1
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.0018 0.0043
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.0018 0.0043
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0018 0.0018 0.0009
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.0018 0.0043
Onchocerca volvulus 0.0286 0.0835 0.0889
Schistosoma mansoni hypothetical protein 0.0081 0.0209 0.0963
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0196 0.056 0.2653
Loa Loa (eye worm) tubulin alpha 2 0.0124 0.0342 0.3805
Echinococcus granulosus dnaJ subfamily B 0.0405 0.1195 0.5713
Schistosoma mansoni tubulin subunit alpha 0.0269 0.0781 0.3722
Echinococcus multilocularis ATP binding cassette sub family G 0.003 0.0055 0.0046
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0018 0.0018 0.0043
Brugia malayi RNA recognition motif domain containing protein 0.0201 0.0576 0.0845
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0184 0.0842
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0184 0.078
Entamoeba histolytica tubulin family protein 0.0145 0.0404 0.1657
Brugia malayi Tubulin beta chain 0.0082 0.0213 0.0313
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0018 0.0018 0.0009
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Mycobacterium tuberculosis 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) 0.0645 0.1925 0.2523
Echinococcus multilocularis kinesin family 1 0.0204 0.0586 0.0577
Echinococcus multilocularis tubulin epsilon chain 0.0145 0.0404 0.0395
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.0184 0.027
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.0018 0.0043
Echinococcus granulosus hyperpolarization activated cyclic 0.0018 0.0018 0.0043
Echinococcus granulosus multidrug resistance protein 1 0.0032 0.0062 0.0254
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0188 0.0536 0.2112
Echinococcus granulosus tubulin alpha 3 chain 0.0269 0.0781 0.3722
Mycobacterium tuberculosis Conserved hypothetical protein 0.0188 0.0536 0.0664
Echinococcus multilocularis Tubulin beta 2C chain 0.0145 0.0404 0.0395
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0286 0.0835 0.1225
Mycobacterium ulcerans dehydrogenase 0.0188 0.0536 0.0599
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0268 0.1148
Trypanosoma brucei beta tubulin 0.0145 0.0404 0.1532
Echinococcus granulosus tubulin alpha chain 0.0269 0.0781 0.3722
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0018 0.0018 0.0019
Giardia lamblia Delta tubulin 0.0063 0.0155 0.0505
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Echinococcus multilocularis beta tubulin 0.0145 0.0404 0.0395
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0041 0.016
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0188 0.0536 0.2112
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0192 0.0547 0.2156
Loa Loa (eye worm) dUTP diphosphatase 0.0147 0.0412 0.4595
Loa Loa (eye worm) ShTK domain-containing protein 0.0286 0.0835 0.93
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0032 0.0062 0.0053
Schistosoma mansoni voltage-dependent calcium channel 0.0018 0.0018 0.0043
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0018 0.0018 0.0043
Echinococcus multilocularis multidrug resistance protein 1 0.0032 0.0062 0.0053
Trypanosoma brucei ATP-binding cassette protein, putative 0.003 0.0055 0.0148
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0018 0.0018 0.0009
Echinococcus granulosus two pore calcium channel protein 1 0.0018 0.0018 0.0043
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0184 0.0842
Schistosoma mansoni hypothetical protein 0.0405 0.1195 0.5713
Loa Loa (eye worm) hypothetical protein 0.0061 0.0149 0.166
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0318 0.0932 0.3627
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.056 0.2653
Echinococcus granulosus voltage dependent calcium channel 0.0018 0.0018 0.0043
Echinococcus granulosus Tubulin alpha 1 chain 0.0269 0.0781 0.3722
Plasmodium vivax importin-beta 2, putative 0.0029 0.0052 0.0203
Loa Loa (eye worm) alpha-tubulin 0.0269 0.0781 0.8707
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.003 0.0055 0.0148
Entamoeba histolytica P-glyco protein 6, putative 0.0032 0.0062 0.0147
Echinococcus multilocularis tubulin subunit beta 0.0145 0.0404 0.0395
Trypanosoma cruzi thymidine kinase, putative 0.0767 0.2295 0.9037
Loa Loa (eye worm) histone methyltransferase 0.0018 0.002 0.0224
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0195 0.0556 0.2328
Echinococcus granulosus lysine specific histone demethylase 1A 0.0188 0.0536 0.2539
Schistosoma mansoni hypothetical protein 0.0025 0.004 0.0147
Schistosoma mansoni tar DNA-binding protein 0.0201 0.0576 0.2731
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0268 0.1148
Echinococcus granulosus Niemann Pick C1 protein 0.0278 0.081 0.3859
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0035 0.0131
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0286 0.0835 0.1225
Trypanosoma brucei ABC transporter, putative 0.003 0.0055 0.0148
Leishmania major alpha tubulin 0.0269 0.0781 0.303
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0018 0.0018 0.0043
Echinococcus multilocularis GPCR, family 2 0.0065 0.0161 0.0152
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.01 0.0326
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.0184 0.0193
Trichomonas vaginalis ABC transporter, putative 0.0032 0.0062 0.0247
Schistosoma mansoni cpg binding protein 0.0063 0.0155 0.0705
Schistosoma mansoni cpg binding protein 0.0063 0.0155 0.0705
Loa Loa (eye worm) hypothetical protein 0.0188 0.0536 0.5971
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0018 0.0018 0.0009
Toxoplasma gondii alpha tubulin TUBA1 0.0269 0.0781 0.308
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0063 0.0155 0.0655
Echinococcus granulosus snurportin 1 0.0307 0.0898 0.4281
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.0018 0.0043
Echinococcus granulosus voltage gated hydrogen channel 1 0.0018 0.0018 0.0043
Trichomonas vaginalis tubulin alpha chain, putative 0.0082 0.0213 0.0908
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Schistosoma mansoni alpha tubulin 0.0269 0.0781 0.3722
Entamoeba histolytica fatty acid elongase, putative 0.0084 0.0219 0.084
Entamoeba histolytica fatty acid elongase, putative 0.0084 0.0219 0.084
Leishmania major UDP-galactopyranose mutase 0.0188 0.0536 0.2056
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0052 0.0043
Onchocerca volvulus 0.0188 0.0536 0.0571
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0145 0.0506
Entamoeba histolytica thymidine kinase, putative 0.0767 0.2295 1
Brugia malayi beta-lactamase 0.0072 0.0184 0.027
Schistosoma mansoni tyrosine kinase 0.0305 0.089 0.4245
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.0018 0.0043
Leishmania major hypothetical protein, conserved 0.0025 0.0041 0.009
Echinococcus multilocularis Tubulin alpha 1 chain 0.0269 0.0781 0.0773
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0184 0.078
Loa Loa (eye worm) hypothetical protein 0.005 0.0118 0.131
Loa Loa (eye worm) tubulin alpha 2 0.0206 0.059 0.6579
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0145 0.0657
Echinococcus granulosus voltage dependent calcium channel 0.0018 0.0018 0.0043
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.0184 0.0193
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.003 0.0055 0.0148
Schistosoma mansoni tubulin subunit beta 0.0145 0.0404 0.1903
Leishmania major alpha tubulin 0.0269 0.0781 0.303
Echinococcus multilocularis Tubulin alpha 1 chain 0.0269 0.0781 0.0773
Chlamydia trachomatis deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0147 0.0412 0.1882
Echinococcus multilocularis voltage dependent calcium channel 0.0018 0.0018 0.0009
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0161 0.0152
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.0018 0.0009
Echinococcus granulosus epidermal growth factor receptor 0.0305 0.089 0.4245
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0018 0.0018 0.0009
Loa Loa (eye worm) hypothetical protein 0.0072 0.0184 0.2047
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0846 0.2538 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.0184 0.0193
Trichomonas vaginalis tubulin epsilon chain, putative 0.0145 0.0404 0.1742
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.0184 0.0193
Schistosoma mansoni amine oxidase 0.0188 0.0536 0.2539
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.0018 0.0056
Brugia malayi cation channel family protein 0.0018 0.0018 0.0026
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0035 0.0068
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.0184 0.016
Leishmania major alpha tubulin 0.0269 0.0781 0.303
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.0018 0.0009
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0041 0.016
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.0184 0.0842
Leishmania major thymidine kinase, putative 0.0767 0.2295 0.9037
Echinococcus multilocularis tubulin gamma 1 chain 0.0145 0.0404 0.0395
Entamoeba histolytica tubulin alpha-1 chain 0.0269 0.0781 0.3322
Loa Loa (eye worm) TK/EGFR protein kinase 0.0305 0.089 0.9918
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.0018 0.0043
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0188 0.0536 0.2539
Echinococcus multilocularis neuropeptide s receptor 0.047 0.1395 0.1387
Echinococcus multilocularis tubulin beta 1 chain 0.0145 0.0404 0.0395
Echinococcus granulosus hyperpolarization activated cyclic 0.0018 0.0018 0.0043
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0097 0.026 0.0251
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0846 0.2538 1
Brugia malayi beta-lactamase family protein 0.0072 0.0184 0.027
Trypanosoma cruzi polo-like protein kinase, putative 0.01 0.0268 0.0992
Schistosoma mansoni tubulin subunit alpha 0.0269 0.0781 0.3722
Loa Loa (eye worm) tubulin alpha 2 0.0206 0.059 0.6579
Brugia malayi Furin-like cysteine rich region family protein 0.0305 0.089 0.1307
Schistosoma mansoni tyrosine kinase 0.0164 0.0462 0.2181
Plasmodium vivax tubulin alpha chain, putative 0.0269 0.0781 0.308
Echinococcus granulosus thymidine kinase 0.0331 0.0971 0.4637
Loa Loa (eye worm) TK/INSR protein kinase 0.0097 0.026 0.2897
Echinococcus multilocularis NADH ubiquinone oxidoreductase 42 kDa subunit 0.0074 0.019 0.0181
Echinococcus multilocularis Niemann Pick C1 protein 0.0195 0.0556 0.0547
Echinococcus multilocularis tubulin subunit TubB 0.0269 0.0781 0.0773
Brugia malayi beta-lactamase family protein 0.0072 0.0184 0.027
Plasmodium vivax kinesin-5 0.0027 0.0045 0.0177
Schistosoma mansoni thymidine kinase 0.0331 0.0971 0.4637
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0018 0.0018 0.0019
Echinococcus multilocularis tubulin alpha chain 0.0269 0.0781 0.0773
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.01 0.0326
Plasmodium vivax telomerase reverse transcriptase, putative 0.0846 0.2538 1
Plasmodium vivax hypothetical protein, conserved 0.0188 0.0536 0.2112
Echinococcus granulosus tubulin subunit TubB 0.0269 0.0781 0.3722
Onchocerca volvulus 0.0286 0.0835 0.0889
Mycobacterium tuberculosis Possible oxidoreductase 0.0188 0.0536 0.0664
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Brugia malayi cyclin-dependent kinase 9 0.0048 0.0109 0.016
Schistosoma mansoni tubulin subunit beta 0.0145 0.0404 0.1903
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0041 0.016
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0188 0.0536 1
Plasmodium falciparum multidrug resistance protein 1 0.0032 0.0062 0.0243
Trichomonas vaginalis ABC transporter, putative 0.0032 0.0062 0.0247
Loa Loa (eye worm) hypothetical protein 0.0084 0.0218 0.243
Schistosoma mansoni multidrug resistance protein 0.0032 0.0062 0.0254
Schistosoma mansoni hypothetical protein 0.014 0.0389 0.183
Echinococcus granulosus tubulin alpha chain 0.0269 0.0781 0.3722
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0018 0.0018 0.0009
Echinococcus multilocularis ATP binding cassette sub family B 0.0031 0.006 0.0051
Trichomonas vaginalis esterase, putative 0.0072 0.0184 0.078
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0145 0.0112
Brugia malayi Kinesin motor domain containing protein 0.0027 0.0045 0.0066
Schistosoma mansoni tyrosinase precursor 0.0286 0.0835 0.3978
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0018 0.0018 0.0009
Echinococcus multilocularis tar DNA binding protein 0.0201 0.0576 0.0567
Trichomonas vaginalis tubulin, putative 0.0082 0.0213 0.0908
Echinococcus multilocularis epidermal growth factor receptor 0.0305 0.089 0.0882
Echinococcus multilocularis tubulin alpha chain 0.0269 0.0781 0.0773
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0032 0.0062 0.0247
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0018 0.0018 0.0026
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Echinococcus granulosus tubulin beta 1 chain 0.0145 0.0404 0.1903
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0184 0.078
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.01 0.0326
Loa Loa (eye worm) calcium channel 0.0018 0.0018 0.02
Mycobacterium ulcerans deoxycytidine triphosphate deaminase 0.0051 0.012 0.008
Echinococcus multilocularis transient receptor potential ion channel A 0.0094 0.0249 0.024
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0033 0.0113
Toxoplasma gondii alpha-tubulin I, putative 0.0269 0.0781 0.308
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Schistosoma mansoni hypothetical protein 0.0178 0.0505 0.239
Schistosoma mansoni ran 0.0021 0.0028 0.0093
Echinococcus granulosus Tubulin alpha 1 chain 0.0269 0.0781 0.3722
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0028 0.0112
Echinococcus granulosus insulin receptor 0.0097 0.026 0.1209
Loa Loa (eye worm) hypothetical protein 0.0072 0.0184 0.2047
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0222 0.0638 0.269
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0151 0.0422 0.1604
Echinococcus granulosus tubulin delta chain 0.0063 0.0155 0.0704
Echinococcus multilocularis neuropeptide receptor A26 0.047 0.1395 0.1387
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Echinococcus granulosus short transient receptor potential channel 6 0.0079 0.0203 0.0933
Brugia malayi ABC transporter family protein 0.0025 0.0042 0.0061
Leishmania major importin beta-1 subunit, putative 0.0023 0.0035 0.0068
Echinococcus multilocularis sodium leak channel non selective protein 0.0018 0.0018 0.0009
Trichomonas vaginalis thymidine kinase, putative 0.0767 0.2295 1
Loa Loa (eye worm) tubulin alpha chain 0.0269 0.0781 0.8707
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0188 0.0536 0.2112
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0018 0.0018 0.0043
Echinococcus multilocularis geminin 0.0697 0.2085 0.2077
Loa Loa (eye worm) hypothetical protein 0.0195 0.0556 0.6195
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0032 0.0062 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0218 0.093
Brugia malayi hypothetical protein 0.0016 0.0013 0.002
Trypanosoma cruzi polo-like protein kinase, putative 0.01 0.0268 0.0992
Leishmania major alpha tubulin 0.0269 0.0781 0.303
Entamoeba histolytica hypothetical protein 0.017 0.0482 0.2003
Echinococcus multilocularis two pore calcium channel protein 1 0.0018 0.0018 0.0009
Loa Loa (eye worm) tubulin beta chain 0.0145 0.0404 0.4501
Schistosoma mansoni multidrug resistance protein 0.0032 0.0062 0.0254
Brugia malayi ABC transporter family protein 0.0032 0.0062 0.0091
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0018 0.0018 0.0026
Trypanosoma brucei zeta tubulin 0.0063 0.0155 0.0544
Loa Loa (eye worm) hypothetical protein 0.0072 0.0184 0.2047
Brugia malayi Telomerase reverse transcriptase 0.2252 0.6812 1
Echinococcus multilocularis multidrug resistance protein 1 0.0032 0.0062 0.0053
Echinococcus granulosus neuropeptide s receptor 0.047 0.1395 0.6676
Brugia malayi dUTP diphosphatase 0.0147 0.0412 0.0605
Schistosoma mansoni tar DNA-binding protein 0.0201 0.0576 0.2731
Echinococcus multilocularis tubulin alpha chain 0.0269 0.0781 0.0773
Giardia lamblia Thymidine kinase 0.0767 0.2295 0.9033
Echinococcus multilocularis sterol regulatory element binding protein 0.0084 0.0218 0.0209
Loa Loa (eye worm) BEN-1 protein 0.0145 0.0404 0.4501
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0145 0.1617
Trichomonas vaginalis ABC transporter, putative 0.0032 0.0062 0.0247
Trypanosoma cruzi ATP-binding cassette protein, putative 0.003 0.0055 0.0148
Echinococcus granulosus sodium leak channel non selective protein 0.0018 0.0018 0.0043
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0018 0.0018 0.0026
Brugia malayi Transient-receptor-potential like protein 0.005 0.0118 0.0173
Echinococcus multilocularis tubulin alpha 3 chain 0.0269 0.0781 0.0773
Trypanosoma cruzi UDP-galactopyranose mutase 0.0188 0.0536 0.2056
Schistosoma mansoni tar DNA-binding protein 0.0201 0.0576 0.2731
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0318 0.0932 0.3627
Loa Loa (eye worm) tubulin alpha-3 chain 0.0187 0.0533 0.5934
Trypanosoma cruzi tubulin gamma chain 0.0145 0.0404 0.1532
Trypanosoma brucei beta tubulin 0.0145 0.0404 0.1532
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.0184 0.0193
Schistosoma mansoni tubulin subunit beta 0.0145 0.0404 0.1903
Chlamydia trachomatis deoxycytidine triphosphate deaminase 0.0051 0.012 0.0311
Giardia lamblia Deoxynucleoside kinase 0.0074 0.019 0.0643
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.0018 0.0043
Trichomonas vaginalis tubulin alpha chain, putative 0.0082 0.0213 0.0908
Schistosoma mansoni two-pore calcium channel 0.0018 0.0018 0.0043
Echinococcus multilocularis insulin receptor 0.0097 0.026 0.0251
Echinococcus multilocularis peroxisome assembly protein 26 0.0269 0.0781 0.0773
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0032 0.0062 0.0247
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0028 0.0042
Mycobacterium ulcerans beta-ketoacyl synthase-like protein 0.0645 0.1925 0.2329
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0018 0.0018 0.0071
Entamoeba histolytica ABC transporter, putative 0.003 0.0055 0.0119
Brugia malayi ShTK domain containing protein 0.0286 0.0835 0.1225
Brugia malayi Tubulin beta-1 chain 0.0145 0.0404 0.0593
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.0018 0.0056
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0018 0.0018 0.0071
Schistosoma mansoni hypothetical protein 0.0307 0.0898 0.4281
Schistosoma mansoni ran 0.0021 0.0028 0.0093
Echinococcus multilocularis protein patched 0.0084 0.0218 0.0209
Echinococcus granulosus transient receptor potential gamma protein 0.0111 0.0302 0.1414
Echinococcus multilocularis TRP (transient receptor potential) channel 0.005 0.0118 0.0109
Schistosoma mansoni voltage-gated ion channel 0.0018 0.0018 0.0043
Schistosoma mansoni hypothetical protein 0.0081 0.0209 0.0963
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0196 0.056 0.6236
Schistosoma mansoni multidrug resistance protein 0.0032 0.0062 0.0254
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0018 0.0018 0.0043
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0645 0.1925 0.2329
Giardia lamblia Alpha-tubulin 0.0269 0.0781 0.3001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Chlamydia trachomatis oxoacyl-ACP synthase III 0.0645 0.1925 1
Toxoplasma gondii beta tubulin 0.0145 0.0404 0.1592
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Schistosoma mansoni transient receptor potential channel 0.0111 0.0302 0.1414
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0018 0.0018 0.0043
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0032 0.0062 0.0254
Loa Loa (eye worm) hypothetical protein 0.0188 0.0536 0.5971
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0018 0.0018 0.0043
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0196 0.056 0.2653
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.0018 0.0009
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0018 0.0018 0.0026
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0028 0.0042
Echinococcus granulosus tubulin alpha chain 0.0269 0.0781 0.3722
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0018 0.0018 0.0043
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Echinococcus granulosus tubulin alpha 1C chain 0.0269 0.0781 0.3722
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.0018 0.0009
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0018 0.0018 0.0043
Brugia malayi latrophilin 2 splice variant baaae 0.014 0.0389 0.0571
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0032 0.0062 0.0247
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0018 0.0018 0.02
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0268 0.1148
Plasmodium vivax multidrug resistance protein 1, putative 0.0032 0.0062 0.0243
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.01 0.0268 0.0259
Onchocerca volvulus 0.0286 0.0835 0.0889
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0196 0.056 0.0822
Trypanosoma brucei beta tubulin 0.0145 0.0404 0.1532
Trichomonas vaginalis tubulin gamma chain, putative 0.0145 0.0404 0.1742
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0028 0.0112
Schistosoma mansoni alpha tubulin 0.0269 0.0781 0.3722
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Giardia lamblia Alpha-tubulin 0.0269 0.0781 0.3001
Entamoeba histolytica P-glycoprotein-2, putative 0.0032 0.0062 0.0147
Echinococcus multilocularis transfer RNA-Ile 0.0331 0.0971 0.0963
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0018 0.0018 0.0026
Giardia lamblia Beta tubulin 0.0145 0.0404 0.1497
Schistosoma mansoni hypothetical protein 0.0065 0.0161 0.0731
Plasmodium falciparum deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0147 0.0412 0.1625
Schistosoma mansoni transient receptor potential channel 0.0079 0.0203 0.0933
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0196 0.056 0.0551
Loa Loa (eye worm) hypothetical protein 0.0072 0.0184 0.2047
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.0018 0.0043
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0196 0.056 0.0551
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase, putative 0.0051 0.012 0.0403
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0018 0.0018 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0184 0.0658
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0018 0.0018 0.0009
Mycobacterium tuberculosis Conserved protein 0.0072 0.0184 0.0193
Echinococcus granulosus tubulin gamma 1 chain 0.0145 0.0404 0.1903
Loa Loa (eye worm) hypothetical protein 0.0187 0.0533 0.5934
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.0184 0.0193
Echinococcus granulosus importin subunit beta 1 0.0029 0.0052 0.0205
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0018 0.0018 0.0026
Plasmodium falciparum tubulin beta chain 0.0145 0.0404 0.1592
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0018 0.0018 0.0009
Echinococcus granulosus multidrug resistance protein 1 0.0032 0.0062 0.0254
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.2482 0.7512 1
Schistosoma mansoni kinesin eg-5 0.0027 0.0045 0.0172
Brugia malayi beta-tubulin, identical 0.0145 0.0404 0.0593
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0041 0.009
Mycobacterium leprae Probable lipase LipE 0.0072 0.0184 0.1538
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Echinococcus granulosus tubulin subunit beta 0.0145 0.0404 0.1903
Echinococcus granulosus TRP transient receptor potential channel 0.005 0.0118 0.0523
Echinococcus multilocularis transient receptor potential gamma protein 0.0111 0.0302 0.0294
Echinococcus multilocularis tubulin alpha 3 chain 0.0269 0.0781 0.0773
Schistosoma mansoni transient receptor potential channel 4 0.0111 0.0302 0.1414
Trypanosoma brucei epsilon tubulin 0.0145 0.0404 0.1532
Schistosoma mansoni hypothetical protein 0.0697 0.2085 1
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0032 0.0062 0.0247
Plasmodium falciparum tubulin delta chain, putative 0.0063 0.0155 0.0611
Leishmania major mitochondrial DNA polymerase beta 0.0318 0.0932 0.3627
Echinococcus multilocularis Tubulin beta 2C chain 0.0145 0.0404 0.0395
Toxoplasma gondii histone lysine methyltransferase SET1 0.0113 0.0307 0.121
Giardia lamblia Beta tubulin 0.0145 0.0404 0.1497
Loa Loa (eye worm) hypothetical protein 0.014 0.0389 0.4334
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0032 0.0062 0.0254
Trypanosoma brucei alpha tubulin 0.0269 0.0781 0.303
Schistosoma mansoni tubulin subunit beta 0.0145 0.0404 0.1903
Echinococcus multilocularis epidermal growth factor receptor 0.0164 0.0462 0.0453
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.0018 0.0009
Echinococcus granulosus transient receptor potential ion channel A 0.0094 0.0249 0.1154
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0018 0.0018 0.02
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0028 0.0042
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0145 0.0404 0.1592
Brugia malayi Tubulin alpha chain 0.0063 0.0155 0.0228
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0018 0.0018 0.0043
Trichomonas vaginalis abcb9, putative 0.0032 0.0062 0.0247
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0031 0.006 0.0244
Trichomonas vaginalis tubulin epsilon chain, putative 0.0269 0.0781 0.339
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0018 0.0018 0.0026
Trypanosoma cruzi alpha tubulin, putative 0.0269 0.0781 0.303
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.003 0.0055 0.0218
Schistosoma mansoni hypothetical protein 0.0065 0.0161 0.0731
Giardia lamblia Kinase, PLK 0.01 0.0268 0.0955
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Echinococcus granulosus Niemann Pick C1 protein 0.0195 0.0556 0.2635
Treponema pallidum deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) 0.0147 0.0412 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0052 0.0133
Brugia malayi Tubulin alpha-2 chain 0.0269 0.0781 0.1147
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0028 0.0093
Toxoplasma gondii kinesin motor domain-containing protein 0.0027 0.0045 0.0177
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0018 0.0018 0.0009
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0032 0.0062 0.0247
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0018 0.0043
Entamoeba histolytica hypothetical protein 0.0074 0.019 0.0712
Schistosoma mansoni tar DNA-binding protein 0.0201 0.0576 0.2731
Echinococcus granulosus shaker cognate 0.0018 0.0018 0.0043
Brugia malayi serine/threonine-protein kinase plk-2 0.01 0.0268 0.0393
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0097 0.026 0.1209
Entamoeba histolytica hypothetical protein 0.0074 0.019 0.0712
Loa Loa (eye worm) hypothetical protein 0.0065 0.0161 0.1791
Plasmodium falciparum tubulin gamma chain 0.0145 0.0404 0.1592
Echinococcus granulosus kinesin family 1 0.0204 0.0586 0.2779
Schistosoma mansoni importin beta-1 0.0029 0.0052 0.0205
Plasmodium falciparum telomerase reverse transcriptase 0.0846 0.2538 1
Leishmania major beta tubulin 0.0145 0.0404 0.1532
Schistosoma mansoni vesicular amine transporter 0.0018 0.0018 0.0043
Plasmodium falciparum kinesin-5 0.0027 0.0045 0.0177
Entamoeba histolytica kinesin, putative 0.0027 0.0045 0.0072
Echinococcus multilocularis hypothetical protein 0.0269 0.0781 0.0773
Loa Loa (eye worm) tyrosinase 1 0.0286 0.0835 0.93
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.02
Schistosoma mansoni 60S ribosomal protein L21 0.0018 0.0018 0.0043

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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