Detailed information for compound 1295750

Basic information

Technical information
  • TDR Targets ID: 1295750
  • Name: N-butan-2-yl-3-(4-chlorophenyl)sulfanyl-6-met hyl-1H-indole-2-carboxamide
  • MW: 372.912 | Formula: C20H21ClN2OS
  • H donors: 2 H acceptors: 1 LogP: 6.05 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC(NC(=O)c1[nH]c2c(c1Sc1ccc(cc1)Cl)ccc(c2)C)C
  • InChi: 1S/C20H21ClN2OS/c1-4-13(3)22-20(24)18-19(25-15-8-6-14(21)7-9-15)16-10-5-12(2)11-17(16)23-18/h5-11,13,23H,4H2,1-3H3,(H,22,24)
  • InChiKey: LXKAIZBAMAAPHO-UHFFFAOYSA-N  

Network

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Synonyms

  • 3-(4-chlorophenyl)sulfanyl-6-methyl-N-sec-butyl-1H-indole-2-carboxamide
  • 3-[(4-chlorophenyl)thio]-6-methyl-N-sec-butyl-1H-indole-2-carboxamide
  • E018-0946
  • NCGC00120094-01

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0086 0.0367 0.0746
Loa Loa (eye worm) patched family protein 0.0012 0.0025 0.0098
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0035 0.0278
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0143 0.0215
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0034 0.0129 0.0136
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0198 0.0887 0.7124
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.0016 0.0048
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0007 0.0003
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0095 0.0411 0.0836
Echinococcus granulosus casein kinase ii subunit beta 0.0037 0.0139 0.021
Trypanosoma cruzi FHA domain containing protein, putative 0.0049 0.0199 0.1306
Brugia malayi MH2 domain containing protein 0.0008 0.0007 0.001
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0034 0.0129 0.0136
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.00000000003788 0.00000000030467
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0069 0.0085
Toxoplasma gondii ATPase, AAA family protein 0.0049 0.0199 0.0189
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0139 0.1083
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0108 0.0136
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.0019 0.0008
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0086 0.0367 0.0746
Loa Loa (eye worm) Smad1 0.0008 0.0007 0.001
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0108 0.0502
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.003 0.0017
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0182 0.0815 0.0787
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0109 0.0473 0.0963
Trypanosoma brucei unspecified product 0.0063 0.0263 0.1787
Brugia malayi Patched family protein 0.0012 0.0025 0.0098
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0208 0.1364
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0061 0.0494
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0108 0.0502
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0061 0.0275
Echinococcus multilocularis lysine specific histone demethylase 1A 0.002 0.0064 0.0078
Brugia malayi Patched family protein 0.0012 0.0025 0.0098
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0298 0.1353 0.2658
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0199 0.1306
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0047 0.0187 0.0381
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0019 0.0064
Echinococcus granulosus histone deacetylase 6 0.0328 0.1492 0.2325
Brugia malayi Protein kinase domain containing protein 0.018 0.0804 0.3906
Loa Loa (eye worm) XPG I-region family protein 0.0011 0.0019 0.0066
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Echinococcus multilocularis histone deacetylase 6 0.0322 0.1463 0.1938
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.003 0.0038
Plasmodium vivax importin-beta 2, putative 0.0029 0.0105 0.0092
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0108 0.0161
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0143 0.1111
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0293 0.1996
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0108 0.0161
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0139 0.1121
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.003 0.0107 0.0218
Echinococcus granulosus Niemann Pick C1 protein 0.0198 0.0887 0.1379
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0035 0.0145
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0009 0.0013 0.0002
Trichomonas vaginalis flap endonuclease-1, putative 0.0052 0.0211 0.17
Echinococcus multilocularis smad 0.0008 0.0007 0.0003
Brugia malayi acetyltransferase, GNAT family protein 0.0145 0.0641 0.3112
Echinococcus granulosus GPCR family 2 0.008 0.0341 0.0526
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0143 0.0183
Loa Loa (eye worm) patched family protein 0.0012 0.0025 0.0098
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.0425 0.2899
Schistosoma mansoni hypothetical protein 0.0084 0.0361 0.0556
Echinococcus granulosus histone deacetylase 6 0.0322 0.1463 0.2279
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.003 0.0141
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0013 0.0102
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0009 0.0013 0.001
Echinococcus granulosus snurportin 1 0.0311 0.1412 0.2199
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0106 0.0093
Toxoplasma gondii thioredoxin reductase 0.0037 0.0144 0.0133
Leishmania major DNA polymerase eta, putative 0.0054 0.022 0.1446
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0042 0.0278
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0182 0.0815 0.0787
Echinococcus multilocularis acetylcholinesterase 0.0278 0.1258 0.1665
Toxoplasma gondii ck2 beta subunit 0.0037 0.0139 0.0129
Onchocerca volvulus 0.003 0.0108 0.0964
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.026 0.1178 0.1834
Brugia malayi Carboxylesterase family protein 0.0278 0.1258 0.6129
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0145
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0104 0.0484
Brugia malayi histone deacetylase 1 (HD1) 0.0274 0.1243 0.6056
Onchocerca volvulus 0.0034 0.0129 0.1167
Leishmania major histone deacetylase, putative 0.0322 0.1463 1
Giardia lamblia Exonuclease 1 0.0011 0.0019 0.0049
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0054 0.022 0.0209
Leishmania major DNA polymerase eta, putative 0.0117 0.0513 0.3463
Schistosoma mansoni acetyl-CoA synthetase 0.0034 0.0129 0.0194
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0066
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0034 0.0129 0.0263
Trypanosoma cruzi cdc2-related kinase 3 0.0045 0.0178 0.1157
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0009 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0145
Plasmodium vivax exonuclease I, putative 0.0011 0.0019 0.0006
Brugia malayi Histone deacetylase family protein 0.0322 0.1463 0.7133
Mycobacterium ulcerans glutaminase 0.0273 0.1237 0.121
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Trichomonas vaginalis protein kinase ck2-beta, putative 0.0011 0.0019 0.0154
Loa Loa (eye worm) patched family protein 0.0012 0.0025 0.0098
Loa Loa (eye worm) hypothetical protein 0.0034 0.0129 0.0608
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.0019 0.015
Echinococcus multilocularis histone deacetylase 3 0.0274 0.1243 0.1646
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0143 0.1058
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0045 0.0178 0.0269
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0057 0.0068
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0139 0.1121
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0473 0.3781
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0145
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0061 0.0075
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0035 0.0132 0.0122
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0139 0.1121
Echinococcus multilocularis dna polymerase kappa 0.0118 0.0518 0.0682
Echinococcus multilocularis GPCR, family 2 0.008 0.0341 0.0447
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.0019 0.015
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0473 0.229
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0083 0.0353 0.0463
Toxoplasma gondii hypothetical protein 0.0012 0.0025 0.0015
Plasmodium falciparum histone deacetylase 1 0.0274 0.1243 0.1232
Mycobacterium ulcerans DNA polymerase IV 0.0118 0.0518 0.049
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0061 0.0088
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0086 0.0367 0.0624
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.002 0.0064 0.0051
Loa Loa (eye worm) flap endonuclease-1 0.0052 0.0211 0.1009
Mycobacterium tuberculosis Carboxylesterase LipT 0.0047 0.0187 0.0381
Plasmodium vivax SET domain protein, putative 0.003 0.0111 0.0098
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.00000000003788 0.00000000030467
Loa Loa (eye worm) histone deacetylase 11 0.0135 0.0599 0.2902
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0025
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0111 0.0165
Echinococcus multilocularis neuroglian 0.0016 0.0042 0.0049
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0145
Schistosoma mansoni hypothetical protein 0.008 0.0341 0.0526
Loa Loa (eye worm) hypothetical protein 0.002 0.0064 0.0286
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.003 0.0033
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0.003 0.0178
Schistosoma mansoni hypothetical protein 0.033 0.1501 0.2339
Leishmania major mitochondrial DNA polymerase beta 0.0299 0.1359 0.9286
Echinococcus granulosus twitchin 0.0017 0.0048 0.0067
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0016 0.0042 0.0057
Loa Loa (eye worm) hypothetical protein 0.0088 0.0377 0.1817
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0057 0.0044
Onchocerca volvulus Protein patched homolog 0.0012 0.0025 0.0187
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0108 0.0502
Plasmodium vivax protoporphyrinogen oxidase, putative 0.002 0.0064 0.0051
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0086 0.0367 0.0746
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0054
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.0005 0.0042
Echinococcus granulosus defective proboscis extension response 0.0016 0.0042 0.0057
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0069 0.0312
Trypanosoma cruzi DNA polymerase kappa, putative 0.0118 0.0518 0.3498
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0179
Loa Loa (eye worm) DIX domain-containing protein 0.0009 0.001 0.0025
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0088 0.0538
Schistosoma mansoni hypothetical protein 0.0082 0.0349 0.0538
Brugia malayi Fibronectin type III domain containing protein 0.0016 0.0042 0.0179
Plasmodium falciparum histone deacetylase 2 0.0322 0.1463 0.1453
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0179 0.0801 0.1058
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0037 0.0139 0.0129
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Giardia lamblia DINP protein human, muc B family 0.0098 0.0425 0.3353
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0016 0.0043
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0045 0.0178 0.1157
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0106 0.0076
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.00000000003788 0.00000000030467
Loa Loa (eye worm) histone deacetylase 0.0322 0.1463 0.7133
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0253 0.1145 0.5575
Plasmodium falciparum lipid/sterol:H+ symporter 0.0012 0.0025 0.0013
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0278 0.1258 0.1959
Onchocerca volvulus 0.0047 0.0187 0.1709
Brugia malayi nuclear receptor RXR 0.0014 0.0035 0.0145
Schistosoma mansoni BC026374 protein (S09 family) 0.0047 0.0187 0.0285
Mycobacterium ulcerans acyl-CoA synthetase 0.0034 0.0129 0.01
Leishmania major hypothetical protein, conserved 0.0025 0.0088 0.0538
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0178 0.1428
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0035 0.0145
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0178 0.0269
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.003 0.0019
Mycobacterium ulcerans oxidoreductase 0.002 0.0064 0.0034
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0013 0.0036
Mycobacterium ulcerans hypothetical protein 0.0028 0.0101 0.0072
Loa Loa (eye worm) hypothetical protein 0.0047 0.0187 0.089
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0013 0.0023
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.003 0.0141
Schistosoma mansoni vesicular amine transporter 0.0016 0.0042 0.0057
Echinococcus multilocularis snurportin 1 0.0311 0.1412 0.187
Trypanosoma brucei histone deacetylase 4 0.0322 0.1463 1
Entamoeba histolytica Ran family GTPase 0.0021 0.0069 0.0515
Brugia malayi Carboxylesterase family protein 0.0047 0.0187 0.089
Entamoeba histolytica cell division protein kinase 2, putative 0.0045 0.0178 0.1392
Loa Loa (eye worm) phosphofructokinase 0.0109 0.0473 0.229
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0181
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0108 0.0161
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0473 0.3807
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0162 0.0723 0.1122
Schistosoma mansoni z-protein (S1r protein) 0.0009 0.001 0.0008
Plasmodium falciparum thioredoxin reductase 0.0037 0.0144 0.0131
Brugia malayi nuclear hormone receptor 0.003 0.0108 0.0502
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0111 0.014
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0057 0.0252
Loa Loa (eye worm) hypothetical protein 0.002 0.0064 0.0286
Brugia malayi DKFZp564C0469 protein 0.0049 0.0199 0.0949
Schistosoma mansoni zinc finger protein 0.0014 0.0035 0.0046
Trypanosoma cruzi DNA polymerase kappa, putative 0.0118 0.0518 0.3498
Leishmania major histone deacetylase, putative 0.0274 0.1243 0.8487
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0179
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0034 0.0129 0.0117
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0139 0.1121
Brugia malayi Thioredoxin reductase 0.0037 0.0144 0.0677
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0007 0.0003
Trypanosoma cruzi histone deacetylase, putative 0.0135 0.0599 0.4052
Loa Loa (eye worm) hypothetical protein 0.0278 0.1258 0.6129
Schistosoma mansoni dep domain containing protein 0.0009 0.001 0.0008
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0069 0.041
Giardia lamblia Histone deacetylase 0.0274 0.1243 1
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0106 0.0095
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0165 0.1118
Schistosoma mansoni hypothetical protein 0.008 0.0341 0.0526
Brugia malayi Patched related family protein 12 0.0012 0.0025 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0199 0.1602
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0095 0.0411 0.0836
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0007 0.001
Schistosoma mansoni importin beta-1 0.0029 0.0105 0.0155
Schistosoma mansoni apoptosis regulator bax 0.0083 0.0353 0.0544
Echinococcus granulosus phd:f box containing protein 0.0016 0.0042 0.0058
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0045 0.0178 0.0843
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0035 0.0145
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0118 0.0744
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0108 0.0161
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0043 0.0058
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0253 0.1145 0.5575
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0181
Brugia malayi histone deacetylase 3 (HD3) 0.0274 0.1243 0.6056
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0118 0.0793
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.003 0.024
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0034 0.0129 0.0263
Loa Loa (eye worm) hypothetical protein 0.0274 0.1243 0.6056
Brugia malayi Protein kinase domain containing protein 0.0045 0.0178 0.0843
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0013 0.0036
Echinococcus multilocularis muscleblind protein 0.0448 0.2049 0.2717
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0116 0.0508 0.048
Trichomonas vaginalis glutaminase, putative 0.0273 0.1237 0.9946
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0473 0.3781
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0034 0.0129 0.01
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0035 0.0046
Echinococcus multilocularis expressed conserved protein 0.0186 0.0832 0.1098
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Trypanosoma cruzi cdc2-related kinase 1 0.0045 0.0178 0.1157
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0299 0.1359 0.9289
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.003 0.0141
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0034 0.0129 0.01
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0035 0.0145
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0106 0.085
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0167 0.0155
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1628 0.7529 1
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0034 0.0129 0.01
Mycobacterium ulcerans 6-phosphofructokinase 0.0109 0.0473 0.0445
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.003 0.0141
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0182 0.0815 1
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0473 0.3807
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0042 0.0058
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0108 0.0136
Loa Loa (eye worm) hypothetical protein 0.003 0.0108 0.0502
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.0341 0.0526
Trypanosoma brucei cdc2-related kinase 3 0.0045 0.0178 0.1204
Loa Loa (eye worm) apoptosis regulator protein 0.0083 0.0353 0.1703
Trichomonas vaginalis exonuclease%2C+putative 0.0011 0.0019 0.015
Echinococcus granulosus lysine specific demethylase 5A 0.006 0.025 0.0382
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0042 0.0049
Echinococcus granulosus histone deacetylase 6 0.0322 0.1463 0.2279
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.003 0.024
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0019 0.0154
Giardia lamblia hypothetical protein 0.0011 0.0019 0.0049
Mycobacterium ulcerans dehydrogenase 0.002 0.0064 0.0034
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0083 0.0353 0.0544
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0143 0.1149
Echinococcus multilocularis roundabout 2 0.0016 0.0042 0.0049
Loa Loa (eye worm) histone deacetylase 3 0.0274 0.1243 0.6056
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0042 0.0179
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Echinococcus multilocularis acetylcholinesterase 0.0278 0.1258 0.1665
Echinococcus multilocularis protoporphyrinogen oxidase 0.002 0.0064 0.0078
Brugia malayi Patched family protein 0.0012 0.0025 0.0098
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0162 0.0723 0.1122
Loa Loa (eye worm) hypothetical protein 0.0117 0.0514 0.2491
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0129 0.0263
Toxoplasma gondii exonuclease III APE 0.0019 0.0057 0.0046
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0108 0.0136
Brugia malayi MH2 domain containing protein 0.0008 0.0007 0.001
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0088 0.0077
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0106 0.0093
Brugia malayi Patched family protein 0.0012 0.0025 0.0098
Onchocerca volvulus Protein patched homolog 0.0012 0.0025 0.0187
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Loa Loa (eye worm) hypothetical protein 0.0098 0.0426 0.2057
Entamoeba histolytica Flap nuclease, putative 0.0052 0.0211 0.1665
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0143 0.0918
Brugia malayi ImpB/MucB/SamB family protein 0.0117 0.0513 0.2483
Mycobacterium tuberculosis Conserved hypothetical protein 0.0158 0.0702 0.1427
Brugia malayi Patched family protein 0.0012 0.0025 0.0098
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0047 0.0187 0.0242
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0117 0.0514 0.0486
Chlamydia trachomatis dehyroquinate synthase 0.0116 0.0508 0.048
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0108 0.0161
Trypanosoma brucei histone deacetylase 2 0.0135 0.0599 0.4084
Brugia malayi Latrophilin receptor protein 2 0.008 0.0341 0.1645
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0473 0.3191
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0118 0.0518 0.4166
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Plasmodium vivax flap endonuclease 1, putative 0.0052 0.0211 0.0199
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0182 0.0815 1
Onchocerca volvulus 0.0014 0.0035 0.0278
Loa Loa (eye worm) hypothetical protein 0.0448 0.2049 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.003 0.0141
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0473 0.3807
Brugia malayi Smad1 0.0008 0.0007 0.001
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0042 0.0181
Plasmodium vivax DNA repair protein REV1, putative 0.0028 0.0101 0.0089
Onchocerca volvulus 0.0009 0.001 0.0049
Schistosoma mansoni dishevelled 0.0009 0.001 0.0008
Onchocerca volvulus 0.0012 0.0025 0.0187
Loa Loa (eye worm) hypothetical protein 0.0246 0.1113 0.5419
Brugia malayi Patched family protein 0.0012 0.0025 0.0098
Brugia malayi cell division control protein 2 homolog 0.0045 0.0178 0.0843
Schistosoma mansoni cpg binding protein 0.0029 0.0104 0.0155
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0106 0.0093
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0108 0.0502
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Plasmodium falciparum casein kinase II beta chain 0.0037 0.0139 0.0127
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0299 0.1359 0.9286
Schistosoma mansoni DNA helicase recq5 0.002 0.0061 0.0088
Echinococcus granulosus smad 0.0008 0.0007 0.0003
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.001 0.0014 0.0042
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0047 0.0187 0.1506
Schistosoma mansoni histone deacetylase hda2 0.0135 0.0599 0.0927
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.003 0.0017
Echinococcus multilocularis casein kinase ii subunit beta 0.0037 0.0139 0.0178
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0111 0.0165
Schistosoma mansoni DNA helicase recq1 0.002 0.0061 0.0088
Echinococcus granulosus histone deacetylase 1 0.0274 0.1243 0.1935
Loa Loa (eye worm) hypothetical protein 0.0088 0.0377 0.1817
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.00000000003788 0.00000000030467
Plasmodium falciparum protoporphyrinogen oxidase 0.002 0.0064 0.0051
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.003 0.0017
Brugia malayi hypothetical protein 0.0025 0.0088 0.0403
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.001 0.0007
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0108 0.0964
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0144 0.0923
Loa Loa (eye worm) hypothetical protein 0.0088 0.0377 0.1817
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0108 0.0502
Entamoeba histolytica exonuclease, putative 0.0011 0.0019 0.0109
Toxoplasma gondii histone deacetylase HDAC4 0.0135 0.0599 0.0589
Onchocerca volvulus 0.0034 0.0129 0.1167
Giardia lamblia Casein kinase II beta chain 0.0011 0.0019 0.0053
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0092 0.0395 0.1906
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0043 0.0183
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0114 0.0499 0.0771
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Trypanosoma brucei DNA polymerase kappa, putative 0.0118 0.0518 0.3533
Loa Loa (eye worm) hypothetical protein 0.0049 0.0199 0.0949
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0019 0.0154
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.001 0.0014 0.0042
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0139 0.1121
Echinococcus multilocularis 6 phosphofructokinase 0.0109 0.0473 0.0622
Brugia malayi hypothetical protein 0.0014 0.0035 0.0145
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0116 0.0508 0.0916
Toxoplasma gondii patched family protein 0.0012 0.0025 0.0015
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0088 0.0075
Schistosoma mansoni cpg binding protein 0.0031 0.0112 0.0167
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0042 0.0058
Trypanosoma brucei unspecified product 0.0112 0.0487 0.3324
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.002 0.0064 0.0051
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0047 0.0187 0.0381
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0111 0.014
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0139 0.1083
Schistosoma mansoni coup transcription factor 0.003 0.0108 0.0161
Echinococcus granulosus dna polymerase kappa 0.0118 0.0518 0.0802
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0037 0.0139 0.1259
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0035 0.0145
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0108 0.0964
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0106 0.085
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0061 0.0409
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0179
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0523 0.2532
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0034 0.0129 0.01
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0008 0.0005 0.0042
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0106 0.0093
Loa Loa (eye worm) hypothetical protein 0.0049 0.0199 0.0949
Schistosoma mansoni rotamase 0.0033 0.0121 0.0181
Trichomonas vaginalis histone deacetylase, putative 0.0274 0.1243 1
Schistosoma mansoni DNA ligase IV 0.0049 0.0199 0.0303
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0179 0.0801 0.3893
Loa Loa (eye worm) acetyltransferase 0.0145 0.0641 0.3112
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.003 0.0141
Entamoeba histolytica hypothetical protein 0.0049 0.0199 0.1567
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0047 0.0187 0.0285
Brugia malayi tailless protein 0.0014 0.0035 0.0145
Leishmania major hypothetical protein, conserved 0.0011 0.0019 0.0064
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.0005 0.0042
Brugia malayi ImpB/MucB/SamB family protein 0.0092 0.0395 0.1906
Echinococcus multilocularis protein dispatched 1 0.0097 0.0419 0.055
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0034 0.0129 0.0136
Echinococcus multilocularis BC026374 protein (S09 family) 0.0047 0.0187 0.0242
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0142 0.0627 0.4281
Loa Loa (eye worm) hypothetical protein 0.002 0.0064 0.0286
Schistosoma mansoni neuroligin 3 (S09 family) 0.0047 0.0187 0.0285
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.0019 0.015
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0019 0.0154
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0108 0.0502
Loa Loa (eye worm) hypothetical protein 0.003 0.0108 0.0502
Onchocerca volvulus 0.0047 0.0187 0.1709
Echinococcus multilocularis microtubule associated protein 2 0.1386 0.6402 0.8503
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Brugia malayi Niemann-Pick C1 protein precursor 0.0198 0.0887 0.4315
Brugia malayi Patched family protein 0.0012 0.0025 0.0098
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.026 0.1178 0.1834
Chlamydia trachomatis protoporphyrinogen oxidase 0.002 0.0064 0.0034
Echinococcus granulosus histone deacetylase 7 0.0322 0.1463 0.2279
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0101 0.0684
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0139 0.1121
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0179 0.0801 0.1244
Brugia malayi RNA, U transporter 1 0.0083 0.0354 0.1705
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0108 0.0502
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0162 0.0723 0.0954
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0083 0.0353 0.0463
Entamoeba histolytica acyl-CoA synthetase, putative 0.0117 0.0514 0.4112
Mycobacterium tuberculosis Probable reductase 0.0086 0.0367 0.0746
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0049 0.0199 0.0189
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0049 0.0199 0.1567
Brugia malayi hypothetical protein 0.0016 0.0043 0.0183
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0052 0.0211 0.139
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.001 0.0016 0.0005
Onchocerca volvulus 0.0151 0.067 0.624
Schistosoma mansoni regulator of G protein signaling 0.0009 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.026 0.1178 0.5739
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0061 0.0494
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0108 0.0502
Schistosoma mansoni 3-dehydroquinate synthase 0.0116 0.0508 0.0786
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0145
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0088 0.0589
Schistosoma mansoni glutaminase 0.0273 0.1237 0.1925
Toxoplasma gondii hypothetical protein 0.0048 0.0194 0.0183
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0108 0.0161
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0009 0.0013 0.0002
Schistosoma mansoni nephrin 0.0016 0.0042 0.0057
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0035 0.0046
Echinococcus granulosus sterol regulatory element binding protein 0.0085 0.0363 0.056
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0034 0.0129 0.0826
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0143 0.0215
Loa Loa (eye worm) histone deacetylase 7A 0.0322 0.1463 0.7133
Plasmodium falciparum glutathione reductase 0.0037 0.0144 0.0131
Schistosoma mansoni hypothetical protein 0.0082 0.0349 0.0538
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0179
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0037 0.0139 0.0894
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). 0.1065 0.4916 1
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0007 0.0003
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0061 0.0275
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0151 0.0138
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0034 0.0129 0.0263
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0179 0.0801 0.1244
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0108 0.0161
Loa Loa (eye worm) patched family protein 0.0012 0.0025 0.0098
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0106 0.1119
Schistosoma mansoni dishevelled 0.0009 0.001 0.0008
Brugia malayi SWIRM domain containing protein 0.002 0.0064 0.0286
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0199 0.1602
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Loa Loa (eye worm) hypothetical protein 0.0186 0.0834 0.4056
Echinococcus granulosus Protein patched homolog 1 0.0085 0.0363 0.056
Echinococcus granulosus FTZ F1 alpha 0.003 0.0108 0.0161
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.00000000003788 0.00000000030467
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0108 0.0161
Brugia malayi hypothetical protein 0.0151 0.067 0.3252
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0111 0.0165
Brugia malayi Pre-SET motif family protein 0.003 0.0111 0.0517
Onchocerca volvulus 0.0049 0.0199 0.1821
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0108 0.0502
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0007 0.0003
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.0019 0.0008
Schistosoma mansoni hypothetical protein 0.0082 0.0349 0.0538
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0105 0.0705
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0116 0.0508 0.1034
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0145
Plasmodium falciparum DNA repair protein REV1, putative 0.0028 0.0101 0.0089
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Plasmodium vivax histone deacetylase, putative 0.0322 0.1463 0.1453
Echinococcus multilocularis protein patched 0.0085 0.0363 0.0476
Brugia malayi Patched family protein 0.0012 0.0025 0.0098
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.003 0.0141
Schistosoma mansoni Lysine-specific histone demethylase 1 0.002 0.0064 0.0091
Leishmania major ATP-dependent phosphofructokinase 0.0109 0.0473 0.3191
Onchocerca volvulus 0.0117 0.0514 0.478
Brugia malayi hypothetical protein 0.0049 0.0199 0.0949
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0108 0.0136
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0143 0.1149
Chlamydia trachomatis DNA ligase 0.0049 0.0199 0.017
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0019 0.0154
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0034 0.0129 0.1004
Leishmania major DNA polymerase kappa, putative 0.0098 0.0425 0.2861
Mycobacterium ulcerans acyl-CoA synthetase 0.0117 0.0514 0.0486
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Schistosoma mansoni ran 0.0021 0.0069 0.01
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0108 0.0502
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0108 0.0161
Brugia malayi hypothetical protein 0.0016 0.0043 0.0183
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0108 0.0502
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0061 0.0275
Brugia malayi Patched family protein 0.0012 0.0025 0.0098
Mycobacterium ulcerans acyl-CoA synthetase 0.0034 0.0129 0.01
Entamoeba histolytica recQ family helicase, putative 0.002 0.0061 0.0453
Brugia malayi AMP-binding enzyme family protein 0.0034 0.0129 0.0608
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family 0.0011 0.0019 0.0021
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0167 0.0157
Onchocerca volvulus 0.0098 0.0426 0.3948
Loa Loa (eye worm) hypothetical protein 0.0025 0.0088 0.0403
Echinococcus multilocularis tumor protein p63 0.0671 0.3087 0.4096
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0083 0.0353 0.0544
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0293 0.1996
Echinococcus granulosus intestinal type alkaline phosphatase 0.0162 0.0723 0.1122
Leishmania major acetyl-CoA synthetase, putative 0.0034 0.0129 0.0826
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0057 0.0115
Loa Loa (eye worm) hypothetical protein 0.0049 0.0199 0.0949
Loa Loa (eye worm) hypothetical protein 0.0016 0.0043 0.0183
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0473 0.0732
Plasmodium vivax replication factor C subunit 1, putative 0.0049 0.0199 0.0187
Mycobacterium ulcerans acyl-CoA synthetase 0.0117 0.0514 0.0486
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0146 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0199 0.1602
Plasmodium vivax hypothetical protein, conserved 0.002 0.0064 0.0051
Brugia malayi MH2 domain containing protein 0.0119 0.0523 0.2532
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0057 0.0514
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0098 0.0425 0.0865
Loa Loa (eye worm) hypothetical protein 0.0278 0.1258 0.6129
Echinococcus multilocularis dual specificity 0.018 0.0804 0.1061
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0225 0.1527
Echinococcus multilocularis carboxylesterase 5A 0.0278 0.1258 0.1665
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.001 0.0025
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0069 0.01
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0106 0.085
Giardia lamblia Flap structure-specific endonuclease 0.0052 0.0211 0.1615
Echinococcus multilocularis dnaJ subfamily B 0.0413 0.1886 0.2501
Leishmania major histone deacetylase, putative 0.0274 0.1243 0.8487
Brugia malayi jmjC domain containing protein 0.006 0.025 0.1196
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0016 0.0006
Brugia malayi hypothetical protein 0.0014 0.0035 0.0145
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.00000000003788 0.00000000030467
Schistosoma mansoni nuclear receptor 0.0014 0.0035 0.0046
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0144 0.0131
Echinococcus multilocularis histone deacetylase 7 0.0322 0.1463 0.1938
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0009 0.0013 0.006
Echinococcus multilocularis nibrin 0.0049 0.0199 0.0258
Brugia malayi hypothetical protein 0.0016 0.0042 0.0179
Loa Loa (eye worm) hypothetical protein 0.0049 0.0199 0.0949
Trypanosoma brucei DNA polymerase kappa, putative 0.0118 0.0518 0.3533
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0007 0.001
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.018 0.0804 0.5463
Trypanosoma cruzi DNA polymerase eta, putative 0.0117 0.0513 0.3463
Entamoeba histolytica acyl-CoA synthetase, putative 0.0117 0.0514 0.4112
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.003 0.012
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0109 0.0473 0.0844
Trypanosoma brucei DNA polymerase IV, putative 0.0118 0.0518 0.3533
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0042 0.0181
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0117 0.0514 0.0486
Loa Loa (eye worm) oxidoreductase 0.0034 0.0129 0.0608
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0035 0.0145
Onchocerca volvulus 0.0047 0.0187 0.1709
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0013 0.0076
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.018 0.0804 0.5463
Brugia malayi hypothetical protein 0.0009 0.001 0.0025
Entamoeba histolytica deoxycytidyl transferase, putative 0.0092 0.0395 0.3146
Brugia malayi nuclear receptor NHR-88 0.003 0.0108 0.0502
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0011 0.0019 0.0064
Echinococcus granulosus histone deacetylase 0.0322 0.1463 0.2279
Brugia malayi N-terminal motif family protein 0.0179 0.08 0.389
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0108 0.0161
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0035 0.0046
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0019 0.0154
Echinococcus granulosus histone deacetylase 8 0.0135 0.0599 0.0927
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0139 0.1121
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0108 0.0502
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.003 0.0194
Echinococcus granulosus Smad4 0.0008 0.0007 0.0003
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.002 0.0064 0.0051
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0117 0.0514 0.0929
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0015 0.0015
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0178 0.1428
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.001 0.0007
Brugia malayi hypothetical protein 0.002 0.0064 0.0286
Trypanosoma brucei histone deacetylase, putative 0.0322 0.1463 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0008 0.0004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0013 0.0102
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0139 0.1121
Schistosoma mansoni ap endonuclease 0.0019 0.0057 0.008
Mycobacterium tuberculosis Conserved hypothetical protein 0.0092 0.0395 0.0803
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0117 0.0514 0.0486
Schistosoma mansoni hypothetical protein 0.033 0.1501 0.2339
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0013 0.0102
Plasmodium falciparum acyl-CoA synthetase 0.0088 0.0377 0.0364
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0179
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0042 0.0181
Trichomonas vaginalis rotamase, putative 0.0033 0.0121 0.0974
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Echinococcus granulosus acetylcholinesterase 0.0278 0.1258 0.1959
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0151 0.1121
Schistosoma mansoni hypothetical protein 0.0083 0.0353 0.0544
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0178 0.1428
Echinococcus multilocularis bloom syndrome protein 0.002 0.0061 0.0075
Entamoeba histolytica histone deacetylase, putative 0.0274 0.1243 1
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0143 0.0215
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0007 0.0003
Plasmodium vivax DNA repair protein RAD2, putative 0.0011 0.0019 0.0006
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.025 0.1196
Leishmania major 4-coumarate:coa ligase-like protein 0.0117 0.0514 0.3473
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0086 0.0367 0.0746
Brugia malayi AMP-binding enzyme family protein 0.0117 0.0514 0.2491
Plasmodium falciparum replication factor C subunit 1, putative 0.0049 0.0199 0.0187
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0034 0.0129 0.01
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0035 0.0039
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0035 0.0145
Brugia malayi ecdysteroid receptor 0.003 0.0108 0.0502
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0108 0.0502
Echinococcus multilocularis muscleblind protein 1 0.0448 0.2049 0.2717
Loa Loa (eye worm) hypothetical protein 0.0047 0.0187 0.089
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0013 0.0023
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0009 0.0013 0.0012
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.003 0.0017
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0083 0.0353 0.1703
Schistosoma mansoni exonuclease 0.0011 0.0019 0.0021
Loa Loa (eye worm) hypothetical protein 0.0066 0.0276 0.1326
Echinococcus granulosus 6 phosphofructokinase 0.0109 0.0473 0.0732
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0108 0.0502
Trypanosoma cruzi DNA damage repair protein, putative 0.0028 0.0101 0.0634
Echinococcus granulosus flap endonuclease GEN 1 0.0011 0.0019 0.0021
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0061 0.0494
Trypanosoma brucei histone deacetylase 1 0.0274 0.1243 0.8495
Echinococcus granulosus neuroligin 0.0047 0.0187 0.0285
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0034 0.0129 0.0194
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0019 0.0154
Entamoeba histolytica protein kinase, putative 0.018 0.0804 0.6449
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0088 0.0377 0.0348
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0165 0.107
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0299 0.1359 0.9286
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0523 0.2532
Entamoeba histolytica hypothetical protein 0.0024 0.0079 0.0597
Trypanosoma brucei DNA polymerase kappa, putative 0.0118 0.0518 0.3533
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) 0.1065 0.4916 1
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0019 0.0064
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0061 0.0088
Brugia malayi jmjC domain containing protein 0.0016 0.0042 0.0181
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0045 0.0178 0.1157
Loa Loa (eye worm) hypothetical protein 0.003 0.0108 0.0502
Mycobacterium ulcerans acyl-CoA synthetase 0.0034 0.0129 0.01
Loa Loa (eye worm) hypothetical protein 0.0117 0.0514 0.2491
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0101 0.0684
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0162 0.0723 0.0954
Echinococcus granulosus cpg binding protein 0.0031 0.0112 0.0167
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0011 0.0019 0.0112
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.0341 0.0447
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Loa Loa (eye worm) hypothetical protein 0.003 0.0108 0.0502
Trypanosoma brucei DNA polymerase IV, putative 0.0112 0.0487 0.3324
Mycobacterium ulcerans acyl-CoA synthetase 0.0034 0.0129 0.01
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.0627 0.425
Loa Loa (eye worm) casein kinase II 0.0011 0.0019 0.0068
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0049 0.0199 0.1602
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0144 0.0292
Loa Loa (eye worm) hypothetical protein 0.0047 0.0187 0.089
Onchocerca volvulus 0.0012 0.0025 0.0187
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0108 0.0161
Entamoeba histolytica protein kinase, putative 0.018 0.0804 0.6449
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0057 0.0326
Brugia malayi Pax transcription activation domain interacting protein 0.0049 0.0199 0.0949
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0042 0.003
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0143 0.0966
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0061 0.0396
Loa Loa (eye worm) hypothetical protein 0.003 0.0108 0.0502
Brugia malayi Carboxylesterase family protein 0.0047 0.0187 0.089
Trypanosoma cruzi UDP-galactopyranose mutase 0.002 0.0064 0.0374
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0079 0.0636
Echinococcus multilocularis replication factor c subunit 1 0.0049 0.0199 0.0258
Loa Loa (eye worm) hypothetical protein 0.0016 0.0043 0.0183
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0246 0.0236
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0042 0.0032
Schistosoma mansoni hypothetical protein 0.0413 0.1886 0.2941
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0009 0.0013 0.0012
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0143 0.0918
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0034 0.0129 0.0608
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0106 0.085
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0108 0.0502
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0035 0.0039
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0022 0.0027
Loa Loa (eye worm) hypothetical protein 0.0085 0.0363 0.1752
Plasmodium vivax glutathione reductase, putative 0.0037 0.0144 0.0131
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.005 0.007
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0108 0.0502
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0145
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0057 0.0027
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0042 0.0049
Echinococcus granulosus microtubule associated protein 2 0.1386 0.6402 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0083 0.0354 0.0721
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0017 0.0048 0.0211
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0013 0.0036
Brugia malayi nuclear hormone receptor 0.0014 0.0035 0.0145
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0043 0.0058
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0179 0.0801 0.1058
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0118 0.0107
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0473 0.3807
Schistosoma mansoni smad1 5 8 and 0.0008 0.0007 0.0003
Mycobacterium ulcerans acyl-CoA synthetase 0.0117 0.0514 0.0486
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0143 0.0215
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0139 0.1121
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0111 0.0165
Schistosoma mansoni DNA polymerase eta 0.0117 0.0513 0.0794
Brugia malayi Myosin head containing protein 0.0012 0.0025 0.0098
Trypanosoma brucei DNA polymerase kappa, putative 0.0118 0.0518 0.3533
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0042 0.0049
Brugia malayi AMP-binding enzyme family protein 0.0117 0.0514 0.2491
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0022 0.0072 0.0062
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0057 0.0358
Mycobacterium ulcerans DNA polymerase IV 0.0118 0.0518 0.049
Schistosoma mansoni histone deacetylase 4 5 0.0322 0.1463 0.2279
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0061 0.0275
Toxoplasma gondii propionate-CoA ligase 0.0034 0.0129 0.0119
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0057 0.0505
Loa Loa (eye worm) hypothetical protein 0.008 0.0341 0.1645
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0363 0.2922
Brugia malayi glutaminase DH11.1 0.0273 0.1237 0.6024
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0069 0.041
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.018 0.0804 0.5463
Mycobacterium ulcerans acetyl-CoA synthetase 0.0034 0.0129 0.01
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0049 0.0199 0.1352
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Schistosoma mansoni microtubule-associated protein tau 0.1386 0.6402 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0092 0.0395 0.0518
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.001 0.0008
Treponema pallidum NADH oxidase 0.0013 0.003 0.0169
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0083 0.0354 0.0721
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0179
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0143 0.0183
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0145 0.0641 0.0994
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0034 0.0129 0.0608
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0116 0.0508 0.1034
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0145
Toxoplasma gondii patched family protein 0.0012 0.0025 0.0015
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.018 0.0804 0.3906
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0049 0.0199 0.1306
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0108 0.0136
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0025
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.0341 0.1645
Brugia malayi Patched related family protein 10 0.0012 0.0025 0.0098
Giardia lamblia Kinase, CMGC CDK 0.0045 0.0178 0.134
Loa Loa (eye worm) hypothetical protein 0.0178 0.0797 0.3874
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.008 0.0341 0.0447
Echinococcus multilocularis Immunoglobulin 0.0016 0.0042 0.0049
Trypanosoma cruzi UDP-galactopyranose mutase 0.002 0.0064 0.0374
Echinococcus granulosus expressed protein 0.0033 0.0121 0.0181
Brugia malayi regulator of G-protein signaling egl-10 0.0009 0.001 0.0025
Plasmodium falciparum DNA repair protein RAD2, putative 0.0011 0.0019 0.0006
Trichomonas vaginalis antibiotic synthetase, putative 0.0034 0.0129 0.1041
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0035 0.0039
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0061 0.0049
Loa Loa (eye worm) hypothetical protein 0.003 0.0108 0.0502
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.003 0.0141
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0118 0.0907
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0139 0.1121
Echinococcus granulosus bloom syndrome protein 0.002 0.0061 0.0088
Echinococcus multilocularis 0.002 0.0064 0.0078
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0106 0.085
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0035 0.0046
Trypanosoma brucei DNA polymerase IV, putative 0.0118 0.0518 0.3533
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0095 0.0411 0.0716
Entamoeba histolytica recQ family DNA helicase 0.001 0.0016 0.009
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.001 0.0025
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Trichomonas vaginalis protein kinase ck2-beta, putative 0.0011 0.0019 0.0154
Schistosoma mansoni histone deacetylase 1 2 3 0.0135 0.0599 0.0927
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0037 0.0139 0.0894
Loa Loa (eye worm) hypothetical protein 0.0125 0.0548 0.2656
Loa Loa (eye worm) carboxylesterase 0.0047 0.0187 0.089
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.001 0.0016 0.0043
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0048 0.0211
Trypanosoma cruzi DNA polymerase kappa, putative 0.0118 0.0518 0.3498
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0088 0.0538
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0008 0.0005 0.0042
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0042 0.0226
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0121 0.0974
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0069 0.0056
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.003 0.0141
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0117 0.0514 0.0929
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0049 0.0199 0.1602
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0092 0.0395 0.0609
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0181
Brugia malayi Patched family protein 0.0012 0.0025 0.0098
Loa Loa (eye worm) Csnk2b protein 0.0037 0.0139 0.0656
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Loa Loa (eye worm) hypothetical protein 0.0135 0.0599 0.2902
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0035 0.0046
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0167 0.0157
Plasmodium falciparum glutathione reductase 0.0013 0.003 0.0017
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0009 0.0013 0.0012
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0009 0.0013 0.001
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0049 0.0199 0.2298
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0167 0.0253
Schistosoma mansoni patched 1 0.0085 0.0363 0.056
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0034 0.0129 0.0165
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0069 0.0312
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0034 0.0129 0.0826
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.0019 0.015
Trichomonas vaginalis histone deacetylase, putative 0.0274 0.1243 1
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0088 0.0377 0.0348
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0288 0.1306 0.128
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0101 0.0634
Brugia malayi amine oxidase, flavin-containing family protein 0.002 0.0064 0.0286
Loa Loa (eye worm) carboxylesterase 0.0278 0.1258 0.6129
Mycobacterium ulcerans acyl-CoA synthetase 0.0034 0.0129 0.01
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0009 0.0013 0.0036
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0108 0.0136
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0298 0.1353 0.1327
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.003 0.0194
Echinococcus multilocularis histone deacetylase 6 0.0328 0.1492 0.1977
Entamoeba histolytica DNA-repair protein, putative 0.0011 0.0019 0.0109
Loa Loa (eye worm) hypothetical protein 0.0049 0.0199 0.0949
Brugia malayi Carboxylesterase family protein 0.0047 0.0187 0.089
Plasmodium vivax casein kinase II beta chain, putative 0.0037 0.0139 0.0127
Echinococcus multilocularis histone deacetylase 6 0.0322 0.1463 0.1938
Loa Loa (eye worm) hypothetical protein 0.0198 0.0887 0.4315
Toxoplasma gondii histone deacetylase HDAC2 0.0274 0.1243 0.1234
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0013 0.0076
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0079 0.048
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0311 0.1412 0.6882
Mycobacterium ulcerans acyl-CoA synthetase 0.0034 0.0129 0.01
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0201 0.0901 0.1401
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0079 0.0636
Brugia malayi MH1 domain containing protein 0.0008 0.0007 0.001
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0167 0.1344
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0146 0.0187
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0092 0.0395 0.0609
Brugia malayi Patched family protein 0.0012 0.0025 0.0098
Mycobacterium ulcerans carboxylesterase, LipT 0.0047 0.0187 0.0158
Loa Loa (eye worm) hypothetical protein 0.0253 0.1145 0.5575
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0019 0.0154
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0013 0.0036
Brugia malayi Carboxylesterase family protein 0.0278 0.1258 0.6129
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0045 0.0178 0.0843
Loa Loa (eye worm) hypothetical protein 0.0047 0.0187 0.089
Brugia malayi MH1 domain containing protein 0.0008 0.0007 0.001
Schistosoma mansoni smad1 5 8 and 0.0008 0.0007 0.0003
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0139 0.1121
Trypanosoma brucei chrX additional, unordered contigs 0.0028 0.0101 0.0684
Loa Loa (eye worm) hypothetical protein 0.0088 0.0377 0.1817
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0061 0.0051
Schistosoma mansoni histone deacetylase hda2 0.0328 0.1492 0.2325
Loa Loa (eye worm) acetylcholinesterase 1 0.0278 0.1258 0.6129
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0242 0.0315
Schistosoma mansoni cell adhesion molecule 0.0016 0.0042 0.0057
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0035 0.0145
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0199 0.1306
Brugia malayi Muscleblind-like protein 0.0448 0.2049 1
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0162 0.0723 0.0954
Loa Loa (eye worm) hypothetical protein 0.0132 0.0584 0.2831
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0088 0.0075
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0473 0.229
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.001 0.0007
Brugia malayi AMP-binding enzyme family protein 0.0034 0.0129 0.0608
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Onchocerca volvulus Histone deacetylase 10 homolog 0.0135 0.0599 0.557
Echinococcus multilocularis cyclin dependent kinase 1 0.0045 0.0178 0.0229
Loa Loa (eye worm) hypothetical protein 0.002 0.0064 0.0286
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0054
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0035 0.0046
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0083 0.0354 0.0721
Loa Loa (eye worm) hypothetical protein 0.0193 0.0863 0.4198
Brugia malayi Patched family protein 0.0012 0.0025 0.0098
Loa Loa (eye worm) glutaminase 2 0.0273 0.1237 0.6024
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0037 0.0139 0.0894
Trypanosoma cruzi histone deacetylase, putative 0.0322 0.1463 1
Trypanosoma brucei DNA damage repair protein, putative 0.0028 0.0101 0.0684
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0108 0.0161
Trichomonas vaginalis ran, putative 0.0021 0.0069 0.0555
Echinococcus multilocularis flap endonuclease GEN 1 0.0011 0.0019 0.0018
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0106 0.0095
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0139 0.1121
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0069 0.0059
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0085 0.0363 0.1752
Plasmodium vivax protein kinase Crk2 0.0045 0.0178 0.0165
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0043 0.0183
Schistosoma mansoni hypothetical protein 0.0311 0.1412 0.2199
Echinococcus granulosus nibrin 0.0049 0.0199 0.0303
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0019 0.0154
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0179
Mycobacterium ulcerans protoporphyrinogen oxidase 0.002 0.0064 0.0034
Trypanosoma cruzi cdc2-related kinase 1 0.0045 0.0178 0.1157
Plasmodium vivax histone deacetylase 1, putative 0.0274 0.1243 0.1232
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0061 0.0051
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0108 0.0136
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0047 0.0187 0.0285
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Schistosoma mansoni ap endonuclease 0.0019 0.0057 0.008
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0622 0.0965
Loa Loa (eye worm) hypothetical protein 0.0088 0.0377 0.1817
Loa Loa (eye worm) hypothetical protein 0.0083 0.0353 0.1703
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0199 0.1602
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0139 0.1083
Brugia malayi AMP-binding enzyme family protein 0.0034 0.0129 0.0608
Trypanosoma brucei DNA polymerase kappa, putative 0.0118 0.0518 0.3533
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0106 0.085
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0274 0.1243 1
Brugia malayi nuclear receptor NHR-88 0.0014 0.0035 0.0145
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0035 0.0278
Treponema pallidum DNA ligase (lig) 0.0049 0.0199 0.2291
Brugia malayi Flap endonuclease-1 0.0052 0.0211 0.1009
Plasmodium vivax hypothetical protein, conserved 0.002 0.0064 0.0051
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0042 0.0058
Schistosoma mansoni flap endonuclease-1 0.0047 0.0188 0.0286
Brugia malayi polk-prov protein 0.0055 0.0225 0.1074
Entamoeba histolytica protein kinase domain containing protein 0.018 0.0804 0.6449
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0009 0.001 0.0025
Loa Loa (eye worm) hypothetical protein 0.0173 0.0773 0.3756
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0057 0.0326
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.00000000003788 0.00000000030467
Loa Loa (eye worm) hypothetical protein 0.0016 0.0043 0.0183
Leishmania major hypothetical protein, conserved 0.0016 0.0042 0.0226
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0034 0.0129 0.01
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.00000000003788 0.00000000030467
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0045 0.0178 0.0843
Echinococcus granulosus lysine specific histone demethylase 1A 0.002 0.0064 0.0091
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0143 0.0183
Brugia malayi CHE-14 protein 0.0085 0.0363 0.1752
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0118 0.0744
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0179 0.08 0.7465
Trichomonas vaginalis set domain proteins, putative 0.0237 0.107 0.8609
Schistosoma mansoni cpg binding protein 0.0031 0.0112 0.0167
Schistosoma mansoni hypothetical protein 0.0011 0.0022 0.0027
Entamoeba histolytica recQ family helicase, putative 0.001 0.0015 0.0075
Schistosoma mansoni histone deacetylase 0.0274 0.1243 0.1935
Brugia malayi casein kinase II, putaitve 0.0011 0.0019 0.0068
Loa Loa (eye worm) hypothetical protein 0.0179 0.08 0.389
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0109 0.0473 0.5725
Echinococcus granulosus Niemann Pick C1 protein 0.0283 0.1281 0.1994
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0034 0.0129 0.0608
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0143 0.0215
Toxoplasma gondii histone lysine-specific demethylase 0.002 0.0064 0.0053
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0179
Loa Loa (eye worm) hypothetical protein 0.0047 0.0187 0.089
Schistosoma mansoni acetylcholinesterase 0.0047 0.0187 0.0285
Plasmodium falciparum importin beta, putative 0.0029 0.0105 0.0092
Loa Loa (eye worm) hypothetical protein 0.002 0.0064 0.0286
Brugia malayi Importin beta-1 subunit 0.0029 0.0105 0.0486
Schistosoma mansoni nuclear receptor 0.0014 0.0035 0.0046
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0049 0.0199 0.0949
Loa Loa (eye worm) hypothetical protein 0.0029 0.0105 0.0486
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.001 0.0008
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0042 0.0032
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.001 0.0007
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0016 0.0042 0.0057
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0061 0.0358
Trypanosoma cruzi cdc2-related kinase 3 0.0045 0.0178 0.1157
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0225 0.1527
Entamoeba histolytica exonuclease, putative 0.0011 0.0019 0.0109
Echinococcus multilocularis Niemann Pick C1 protein 0.0283 0.1281 0.1696
Onchocerca volvulus 0.0047 0.0187 0.1709
Trypanosoma brucei DNA repair protein RAD2, putative 0.0011 0.0019 0.0117
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.0341 0.1645
Trichomonas vaginalis antibiotic synthetase, putative 0.0034 0.0129 0.1041
Schistosoma mansoni thyroid hormone receptor 0.003 0.0108 0.0161
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0057 0.0377
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0034 0.0129 0.01
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0042 0.0058
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0143 0.0673
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.008 0.0341 0.0526
Brugia malayi Calcitonin receptor-like protein seb-1 0.0253 0.1145 0.5575
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0165 0.107
Loa Loa (eye worm) hypothetical protein 0.0016 0.0043 0.0183
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0049 0.0199 0.0279
Trypanosoma brucei trypanothione reductase 0.0037 0.0144 0.0972
Echinococcus multilocularis expressed protein 0.0033 0.0121 0.0154
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0061 0.0075
Schistosoma mansoni alkaline phosphatase 0.0162 0.0723 0.1122
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0061 0.0358
Onchocerca volvulus 0.0012 0.0025 0.0187
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0035 0.0039
Echinococcus granulosus BC026374 protein S09 family 0.0047 0.0187 0.0285
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.003 0.0194
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0057 0.0252
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0035 0.0145
Echinococcus granulosus histone deacetylase 3 0.0274 0.1243 0.1935
Echinococcus granulosus alkaline phosphatase 0.0162 0.0723 0.1122
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.025 0.0382
Echinococcus multilocularis histone deacetylase 0.0322 0.1463 0.1938
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0016 0.0017
Schistosoma mansoni alkaline phosphatase 0.0162 0.0723 0.1122
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0106 0.0095
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0105 0.0094
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0022 0.0023
Brugia malayi latrophilin 2 splice variant baaae 0.0173 0.0773 0.3756
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0008 0.0004
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0049 0.0199 0.1602
Loa Loa (eye worm) hypothetical protein 0.0037 0.0143 0.0673
Toxoplasma gondii histone deacetylase HDAC3 0.0274 0.1243 0.1234
Schistosoma mansoni casein kinase II beta subunit 0.0037 0.0139 0.021
Brugia malayi Carboxylesterase family protein 0.0047 0.0187 0.089
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0013 0.006
Brugia malayi steroid hormone receptor 0.003 0.0108 0.0502
Giardia lamblia DNA damage repair protein 0.0028 0.0101 0.0722
Brugia malayi AMP-binding enzyme family protein 0.0034 0.0129 0.0608
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0066
Echinococcus granulosus DNA repair protein complementing XP G cells 0.0011 0.0019 0.0021
Brugia malayi Patched family protein 0.0012 0.0025 0.0098
Loa Loa (eye worm) hypothetical protein 0.0125 0.0548 0.2656
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0145
Loa Loa (eye worm) hypothetical protein 0.003 0.0111 0.0517
Leishmania major UDP-galactopyranose mutase 0.002 0.0064 0.0374
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0009 0.0013 0.0012
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0139 0.1121
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0034 0.0129 0.0826
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0473 0.0732
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0108 0.0964
Mycobacterium ulcerans acyl-CoA synthetase 0.0034 0.0129 0.01
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0034 0.0129 0.0119
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0293 0.1996
Trypanosoma brucei unspecified product 0.0063 0.0263 0.1787
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0144 0.0677
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.001 0.0016 0.0004
Schistosoma mansoni hypothetical protein 0.0083 0.0353 0.0544
Trichomonas vaginalis DNA polymerase eta, putative 0.0118 0.0518 0.4166
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0052 0.0211 0.0201
Echinococcus granulosus cyclin dependent kinase 5 0.0045 0.0178 0.0269
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0035 0.0046
Schistosoma mansoni nuclear hormone receptor 0.003 0.0108 0.0161
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0013 0.003 0.0061
Echinococcus multilocularis histone deacetylase 1 0.0274 0.1243 0.1646
Schistosoma mansoni hypothetical protein 0.0083 0.0353 0.0544
Brugia malayi jmjC domain containing protein 0.0016 0.0042 0.0181
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0117 0.0514 0.1046
Loa Loa (eye worm) carboxylesterase 0.0047 0.0187 0.089
Brugia malayi Patched protein homolog 1 0.0012 0.0025 0.0098
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0069 0.0461
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0121 0.0567
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0011 0.0019 0.0112
Mycobacterium tuberculosis Probable dehydrogenase 0.0086 0.0367 0.0746
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.003 0.0019
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.0064 0.0129
Echinococcus granulosus neuroglian 0.0016 0.0042 0.0057
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0009 0.001 0.0008
Brugia malayi ecdysone receptor 0.0014 0.0035 0.0145
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0025
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0045 0.0178 0.0167
Schistosoma mansoni terminal deoxycytidyl transferase 0.0092 0.0395 0.0609
Schistosoma mansoni cellular tumor antigen P53 0.0098 0.0426 0.0657
Schistosoma mansoni amine oxidase 0.002 0.0064 0.0091
Plasmodium vivax acetyl-CoA synthetase, putative 0.0034 0.0129 0.0117
Brugia malayi hypothetical protein 0.0012 0.0025 0.0098
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.005 0.0059
Echinococcus granulosus Immunoglobulin 0.0016 0.0042 0.0057
Echinococcus multilocularis Niemann Pick C1 protein 0.0198 0.0887 0.1172
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0108 0.0502
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0042 0.0058
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0042 0.0058
Mycobacterium ulcerans hypothetical protein 0.0158 0.0702 0.0674
Echinococcus multilocularis alkaline phosphatase 0.0162 0.0723 0.0954
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0129 0.0263
Echinococcus multilocularis DNA repair protein complementing XP G cells 0.0011 0.0019 0.0018
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0009 0.0013 0.001
Echinococcus multilocularis neuroligin 0.0047 0.0187 0.0242
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0069 0.0056
Loa Loa (eye worm) histone deacetylase 1 0.0274 0.1243 0.6056
Schistosoma mansoni smad1 5 8 and 0.0008 0.0007 0.0003
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0129 0.0263
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Toxoplasma gondii histone deacetylase HDAC1 0.0322 0.1463 0.1454
Brugia malayi protein C24B5.3 0.0012 0.0025 0.0098
Toxoplasma gondii patched family protein 0.0012 0.0025 0.0015
Loa Loa (eye worm) hypothetical protein 0.0151 0.067 0.3252
Onchocerca volvulus 0.0237 0.107 1
Entamoeba histolytica hypothetical protein 0.018 0.0804 0.6449
Onchocerca volvulus 0.002 0.0064 0.0548
Plasmodium vivax histone deacetylase 2, putative 0.0322 0.1463 0.1453
Brugia malayi Csnk2b protein 0.0037 0.0139 0.0656
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0098 0.0425 0.2861
Trypanosoma cruzi histone deacetylase 1, putative 0.0274 0.1243 0.8487
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0042 0.0058
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.0019 0.0008
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0108 0.0161
Leishmania major acetyl-CoA synthetase, putative 0.0034 0.0129 0.0826
Brugia malayi jmjC domain containing protein 0.0016 0.0042 0.0181
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0298 0.1353 0.1344
Echinococcus granulosus para nitrobenzyl esterase 0.0047 0.0187 0.0285
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0043 0.0183
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0555 0.2547 0.3973
Schistosoma mansoni chromosome transmission fidelity factor 0.0049 0.0199 0.0303
Trypanosoma brucei cdc2-related kinase 1 0.0045 0.0178 0.1204
Mycobacterium ulcerans acyl-CoA synthetase 0.0034 0.0129 0.01
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0179 0.0801 0.1244
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0473 0.3781
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0242 0.037
Giardia lamblia Replication factor C, subunit 1 0.0049 0.0199 0.1516
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0103 0.0153
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0179 0.0801 0.1244
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0151 0.1174
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0139 0.1121
Leishmania major importin beta-1 subunit, putative 0.0024 0.0079 0.048
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Schistosoma mansoni hypothetical protein 0.0173 0.0773 0.12
Schistosoma mansoni topbp1 0.0049 0.0199 0.0303
Brugia malayi phosphofructokinase 0.0109 0.0473 0.229
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.018 0.0804 0.5487
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0275
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0057 0.0416
Brugia malayi histone deacetylase 11 0.0135 0.0599 0.2902
Echinococcus granulosus Pleckstrin G protein interacting region 0.0009 0.001 0.0008
Leishmania major histone deacetylase, putative 0.0322 0.1463 1
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0199 0.1602
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0019 0.0154
Schistosoma mansoni hypothetical protein 0.008 0.0341 0.0526
Trypanosoma cruzi histone deacetylase 1, putative 0.0274 0.1243 0.8487
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.0016 0.0048
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0106 0.0076
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0035 0.0046
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0047 0.0187 0.0285
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0028 0.0101 0.0091
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0106 0.0811
Trypanosoma brucei DNA damage repair protein, putative 0.0028 0.0101 0.0684
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0013 0.0036
Loa Loa (eye worm) glutathione reductase 0.0037 0.0144 0.0677
Echinococcus multilocularis cyclin dependent kinase 0.0045 0.0178 0.0229
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.0937 0.4559
Trypanosoma cruzi histone deacetylase, putative 0.0322 0.1463 1
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0129 0.0263
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0117 0.0514 0.0486
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0108 0.0502
Schistosoma mansoni ran 0.0021 0.0069 0.01
Brugia malayi hypothetical protein 0.0009 0.001 0.0025
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0083 0.0353 0.0544
Schistosoma mansoni hypothetical protein 0.0082 0.0349 0.0538
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0079 0.0636
Brugia malayi AMP-binding enzyme family protein 0.0117 0.0514 0.2491
Trichomonas vaginalis histone deacetylase, putative 0.0274 0.1243 1
Trichomonas vaginalis spcc417.12 protein, putative 0.0047 0.0187 0.1506
Brugia malayi 6-phosphofructokinase 0.0109 0.0474 0.2291
Schistosoma mansoni hypothetical protein 0.008 0.0341 0.0526
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0057 0.0326
Loa Loa (eye worm) histone methyltransferase 0.001 0.0016 0.0054
Echinococcus multilocularis cyclin dependent kinase 1 0.0045 0.0178 0.0229
Schistosoma mansoni gliotactin 0.0047 0.0187 0.0285
Echinococcus granulosus dual specificity 0.018 0.0804 0.1248
Echinococcus granulosus exonuclease 1 0.0011 0.0019 0.0021
Brugia malayi conserved hypotetical protein 0.0014 0.0035 0.0145
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.003 0.0141
Echinococcus granulosus acetylcholinesterase 0.0278 0.1258 0.1959
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.0005 0.0042
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0047 0.0187 0.0285
Loa Loa (eye worm) patched family protein 0.0012 0.0025 0.0098
Plasmodium falciparum histone deacetylase, putative 0.0322 0.1463 0.1453
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.001 0.0008
Plasmodium vivax histone deacetylase, putative 0.0135 0.0599 0.0587
Brugia malayi DIX domain containing protein 0.0009 0.001 0.0025
Schistosoma mansoni Smad4 0.0008 0.0007 0.0003
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0117 0.0514 0.1046
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.003 0.0141
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0037 0.0139 0.1259
Echinococcus multilocularis geminin 0.033 0.1501 0.1989
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0179 0.0801 0.1244
Echinococcus multilocularis cyclin dependent kinase 5 0.0045 0.0178 0.0229
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0057 0.0456
Trypanosoma cruzi histone deacetylase, putative 0.0322 0.1463 1
Brugia malayi hypothetical protein 0.0125 0.0548 0.2656
Brugia malayi topoisomerase 0.0049 0.0199 0.0949
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0101 0.0634
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0016 0.0042 0.0049
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0274 0.1243 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0118 0.0518 0.3533
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0034 0.0129 0.0263
Echinococcus granulosus replication factor c subunit 1 0.0049 0.0199 0.0303
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0242 0.037
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.003 0.0194
Schistosoma mansoni smad 0.0008 0.0007 0.0003
Brugia malayi Histone deacetylase family protein 0.0322 0.1463 0.7133
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0179
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0108 0.0502
Plasmodium falciparum exonuclease I, putative 0.0011 0.0019 0.0006
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0016 0.0042 0.0057
Schistosoma mansoni thyroid hormone receptor 0.003 0.0108 0.0161
Onchocerca volvulus 0.003 0.0111 0.0991
Brugia malayi nuclear receptor RXR 0.0016 0.0043 0.0183
Trypanosoma cruzi histone deacetylase, putative 0.0135 0.0599 0.4052
Loa Loa (eye worm) glutaminase 0.0273 0.1237 0.6024
Trypanosoma brucei DNA polymerase kappa, putative 0.0118 0.0518 0.3533
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0179 0.0801 0.3893
Echinococcus granulosus lysine specific histone demethylase 1A 0.002 0.0064 0.0091
Echinococcus granulosus tumor protein p63 0.0671 0.3087 0.4817
Giardia lamblia Casein kinase II beta chain 0.0037 0.0139 0.103
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0106 0.0755
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0019 0.0154
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0013 0.0036
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.001 0.0015 0.0002
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0016 0.0015
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0009 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0178 0.0797 0.3874
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.0064 0.0286
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0057 0.0456
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0108 0.0502
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0034 0.0129 0.0263
Onchocerca volvulus 0.0034 0.0129 0.1167
Loa Loa (eye worm) DR-78 0.0014 0.0035 0.0145
Trichomonas vaginalis histone deacetylase, putative 0.0274 0.1243 1
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0143 0.1149
Mycobacterium tuberculosis Probable oxidoreductase 0.0095 0.0411 0.0836
Echinococcus multilocularis cpg binding protein 0.0031 0.0112 0.0142
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0052 0.0211 0.139
Schistosoma mansoni amine oxidase 0.002 0.0064 0.0091
Loa Loa (eye worm) hypothetical protein 0.003 0.0108 0.0502
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0009 0.001 0.0049
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0008 0.0005 0.0042
Plasmodium falciparum thioredoxin reductase 0.0013 0.003 0.0017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Echinococcus multilocularis Smad4 0.0008 0.0007 0.0003
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0011 0.0019 0.0064
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0057 0.008
Onchocerca volvulus 0.0029 0.0104 0.0928
Schistosoma mansoni topbp1 0.0049 0.0199 0.0303
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0268 0.1212 0.2466
Mycobacterium ulcerans hypothetical protein 0.0117 0.0514 0.0486
Toxoplasma gondii patched family protein 0.0012 0.0025 0.0015
Onchocerca volvulus 0.0034 0.0129 0.1167
Brugia malayi jmjC domain containing protein 0.0016 0.0042 0.0181
Plasmodium vivax JmjC domain containing protein 0.0016 0.0042 0.003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0118 0.0518 0.3498
Trypanosoma brucei DNA polymerase kappa, putative 0.0118 0.0518 0.3533
Brugia malayi XPG I-region family protein 0.0011 0.0019 0.0066
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0035 0.0039
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0037 0.0139 0.0943
Brugia malayi 6-phosphofructokinase 0.0109 0.0473 0.229
Echinococcus granulosus carboxylesterase 5A 0.0278 0.1258 0.1959
Plasmodium vivax patched family protein, putative 0.0012 0.0025 0.0013
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family member 0.0011 0.0019 0.0021
Leishmania major 4-coumarate:coa ligase-like protein 0.0117 0.0514 0.3473
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0049 0.0199 0.1602
Loa Loa (eye worm) hypothetical protein 0.0034 0.0129 0.0608
Echinococcus granulosus muscleblind protein 0.0448 0.2049 0.3196
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0473 0.3228
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.002 0.0064 0.0091
Brugia malayi CXXC zinc finger family protein 0.0029 0.0104 0.0484
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0042 0.0049
Giardia lamblia NADH oxidase lateral transfer candidate 0.0013 0.003 0.014
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0242 0.0315
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0034 0.0129 0.0608
Plasmodium falciparum casein kinase II beta chain 0.0037 0.0139 0.0127
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0108 0.0136
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0178 0.0269
Leishmania major 4-coumarate:coa ligase-like protein 0.0117 0.0514 0.3473
Echinococcus granulosus flap endonuclease 1 0.0052 0.0211 0.0322
Toxoplasma gondii histone deacetylase HDAC5 0.0135 0.0599 0.0589
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0034 0.0129 0.0119
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0298 0.1353 0.1327
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0069 0.0458
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0008 0.0004
Brugia malayi jmjC domain containing protein 0.0059 0.0242 0.1159
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0042 0.0058
Loa Loa (eye worm) RecQ helicase 0.002 0.0061 0.0275
Onchocerca volvulus 0.0012 0.0025 0.0187
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0013 0.0102
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.0019 0.0008
Loa Loa (eye worm) hypothetical protein 0.0104 0.0452 0.2185
Brugia malayi hypothetical protein 0.0012 0.0025 0.0098
Schistosoma mansoni histone deacetylase 4 5 0.0322 0.1463 0.2279
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0035 0.0046
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0035 0.0046
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0019 0.0154
Echinococcus granulosus dna polymerase eta 0.0117 0.0513 0.0794
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Trichomonas vaginalis replication factor C large subunit, putative 0.0049 0.0199 0.1602
Leishmania major DNA polymerase kappa, putative 0.0028 0.0101 0.0634
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0088 0.0377 0.0766
Onchocerca volvulus 0.0014 0.0035 0.0278
Schistosoma mansoni serine/threonine protein kinase 0.018 0.0804 0.1248
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0167 0.1344
Echinococcus granulosus expressed conserved protein 0.0186 0.0832 0.1292
Brugia malayi hypothetical protein 0.0047 0.0187 0.089
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Brugia malayi Patched family protein 0.0012 0.0025 0.0098
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0108 0.0502
Echinococcus granulosus dnaJ subfamily B 0.0413 0.1886 0.2941
Plasmodium falciparum flap endonuclease 1 0.0052 0.0211 0.0199
Echinococcus multilocularis para nitrobenzyl esterase 0.0047 0.0187 0.0242
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0145
Loa Loa (eye worm) hypothetical protein 0.0043 0.0171 0.0812
Loa Loa (eye worm) hypothetical protein 0.0047 0.0187 0.089
Echinococcus multilocularis histone deacetylase 8 0.0135 0.0599 0.0789
Echinococcus granulosus geminin 0.033 0.1501 0.2339
Brugia malayi Patched related family protein 4 0.0012 0.0025 0.0098
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0008 0.0005 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0118 0.0518 0.3533
Trypanosoma brucei DNA polymerase eta, putative 0.0117 0.0513 0.3498
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.0627 0.425
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.0005 0.0042
Echinococcus granulosus cyclin dependent kinase 0.0045 0.0178 0.0269
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0106 0.085
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0108 0.0502
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0016 0.0017
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0043 0.005
Trypanosoma brucei exonuclease, putative 0.0011 0.0019 0.0117
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0034 0.0129 0.0263
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0042 0.0226
Brugia malayi Pre-SET motif family protein 0.0208 0.0937 0.4559
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0016 0.0096
Trichomonas vaginalis histone deacetylase, putative 0.0274 0.1243 1
Brugia malayi nuclear receptor NHR-67 0.0014 0.0035 0.0145
Loa Loa (eye worm) hypothetical protein 0.0117 0.0513 0.2483
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0049 0.0199 0.017
Trichomonas vaginalis rotamase, putative 0.0032 0.0118 0.0945
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.003 0.0141
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0083 0.0354 0.0721
Loa Loa (eye worm) hypothetical protein 0.0047 0.0187 0.089
Loa Loa (eye worm) hypothetical protein 0.0049 0.0199 0.0949
Brugia malayi protein C24B5.3 0.0012 0.0025 0.0098
Leishmania major GTP-binding protein, putative 0.0021 0.0069 0.041
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0035 0.0039
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0088 0.0075
Schistosoma mansoni histone deacetylase 0.0274 0.1243 0.1935
Echinococcus multilocularis exonuclease 1 0.0011 0.0019 0.0018
Trypanosoma cruzi DNA polymerase eta, putative 0.0054 0.022 0.1446
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.003 0.0038
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0105 0.0705
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0111 0.0165
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0057 0.0044
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0121 0.0567
Echinococcus granulosus cyclin dependent kinase 1 0.0045 0.0178 0.0269
Trypanosoma brucei histone deacetylase 3 0.0322 0.1463 1
Mycobacterium ulcerans monoamine oxidase 0.002 0.0064 0.0034
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0105 0.0132
Trichomonas vaginalis histone deacetylase, putative 0.0274 0.1243 1
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0034 0.0129 0.0826
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0035 0.0046
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0145
Brugia malayi hypothetical protein 0.0012 0.0025 0.0098
Plasmodium vivax acyl-CoA synthetase, putative 0.0088 0.0377 0.0364
Giardia lamblia Kinase, CMGC CDK 0.0045 0.0178 0.134
Brugia malayi glutathione reductase 0.0037 0.0144 0.0677
Loa Loa (eye worm) hypothetical protein 0.0117 0.0514 0.2491
Echinococcus multilocularis dna polymerase eta 0.0117 0.0513 0.0675
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0313 0.1421 0.6924
Leishmania major DNA damage repair protein, putative 0.0028 0.0101 0.0634
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0108 0.0502
Echinococcus granulosus importin subunit beta 1 0.0029 0.0105 0.0155
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0143 0.0918
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.025 0.0382
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0015 0.0004
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0019 0.0154
Plasmodium vivax casein kinase II beta chain, putative 0.0037 0.0139 0.0127
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0.003 0.0178
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0108 0.0502
Schistosoma mansoni DNA polymerase IV / kappa 0.0028 0.0101 0.015
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0016 0.0051
Trypanosoma cruzi DNA damage repair protein, putative 0.0028 0.0101 0.0634
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0034 0.0129 0.01
Onchocerca volvulus 0.0012 0.0025 0.0187
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.003 0.0141
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0108 0.0136
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0013 0.0102
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0274 0.1243 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0064 0.0129
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0165 0.107
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0034 0.0129 0.0875
Entamoeba histolytica cell division protein kinase 2, putative 0.0045 0.0178 0.1392
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0019 0.0154
Onchocerca volvulus 0.0012 0.0025 0.0187
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.001 0.0008
Echinococcus multilocularis flap endonuclease 1 0.0052 0.0211 0.0274
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0043 0.0058
Leishmania major trypanothione reductase 0.0037 0.0144 0.0923
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0034 0.0129 0.0875
Loa Loa (eye worm) hypothetical protein 0.0448 0.2049 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0043 0.0183
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0118 0.0744
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0034 0.0129 0.0263
Loa Loa (eye worm) hypothetical protein 0.003 0.0108 0.0502
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0108 0.0161
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0139 0.1121
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0108 0.0161
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0288 0.1306 0.128
Echinococcus multilocularis Immunoglobulin 0.0016 0.0042 0.0049
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0108 0.0161
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0016 0.0043
Echinococcus granulosus roundabout 2 0.0016 0.0042 0.0057
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.026 0.0398
Brugia malayi hypothetical protein 0.0012 0.0025 0.0098
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0052 0.0211 0.1436
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.026 0.1178 0.1559
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0061 0.0049
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0034 0.0129 0.0826
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0108 0.0161
Onchocerca volvulus 0.0047 0.0187 0.1709
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0098
Echinococcus multilocularis sterol regulatory element binding protein 0.0085 0.0363 0.0476
Brugia malayi hypothetical protein 0.0016 0.0046 0.0198
Entamoeba histolytica acyl-coA synthetase, putative 0.0117 0.0514 0.4112
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0145
Brugia malayi Histone deacetylase 1 0.0274 0.1243 0.6056
Onchocerca volvulus 0.0012 0.0025 0.0187
Brugia malayi Patched family protein 0.0012 0.0025 0.0098
Plasmodium falciparum protein kinase 5 0.0045 0.0178 0.0165
Brugia malayi hypothetical protein 0.0049 0.0199 0.0949
Loa Loa (eye worm) hypothetical protein 0.0055 0.0225 0.1074
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0145 0.0641 0.0846
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0145

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) 70.7946 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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