Detailed information for compound 133325

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 414.624 | Formula: C26H42N2O2
  • H donors: 2 H acceptors: 1 LogP: 4.71 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(COc1ccc2c(c1)CCC1C2CCC2(C1CCC2N(C)C)C)CNC(C)C
  • InChi: 1S/C26H42N2O2/c1-17(2)27-15-19(29)16-30-20-7-9-21-18(14-20)6-8-23-22(21)12-13-26(3)24(23)10-11-25(26)28(4)5/h7,9,14,17,19,22-25,27,29H,6,8,10-13,15-16H2,1-5H3
  • InChiKey: QRJWWKRLFSIDAO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis heat shock protein 90 0.0071 0.0053 0.0051
Trypanosoma brucei citrate synthase, putative 0.0046 0.0024 0.0652
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0063 0.0045 0.0043
Schistosoma mansoni glutaminase 0.1705 0.196 0.7872
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Brugia malayi AKH receptor 0.0037 0.0014 0.0072
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0056 0.0037 0.0187
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0333 0.169
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0037 0.0014 0.0018
Echinococcus multilocularis geminin 0.1447 0.1659 0.1658
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0041 0.1135
Brugia malayi exodeoxyribonuclease III family protein 0.006 0.0041 0.021
Brugia malayi tailless protein 0.0056 0.0037 0.0187
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0144
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.012 0.011 0.0109
Loa Loa (eye worm) TAR-binding protein 0.0598 0.0669 0.3412
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0519 0.0576 1
Leishmania major 60S ribosomal protein L19, putative 0.0031 0.0007 0.0203
Onchocerca volvulus 0.0056 0.0037 0.0423
Schistosoma mansoni heat shock protein 0.0071 0.0053 0.0207
Schistosoma mansoni cpg binding protein 0.0138 0.0132 0.0523
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0033 0.0156
Trichomonas vaginalis set domain proteins, putative 0.0766 0.0865 0.4406
Loa Loa (eye worm) hypothetical protein 0.0367 0.0399 0.2038
Brugia malayi heat shock protein 90 0.0071 0.0053 0.0271
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0331 0.0357 1
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0031 0.0007 0.0025
Schistosoma mansoni tar DNA-binding protein 0.0598 0.0669 0.2681
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0037 0.0014 0.0163
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.012 0.011 0.0109
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0027 0.0003 0.0001
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0031 0.0007 0.0151
Toxoplasma gondii hypothetical protein 0.0053 0.0033 0.0525
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0014
Brugia malayi G-protein coupled receptor 0.0037 0.0014 0.0072
Mycobacterium tuberculosis Conserved hypothetical protein 0.0174 0.0174 0.0249
Schistosoma mansoni neuropeptide receptor 0.0037 0.0014 0.005
Loa Loa (eye worm) neuropeptide F receptor 0.0037 0.0014 0.0072
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0178 0.09
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0178 0.09
Schistosoma mansoni patched 1 0.0141 0.0136 0.0539
Schistosoma mansoni alpha-1 adrenergic receptor 0.0037 0.0014 0.005
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0178 0.09
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0041 0.0058
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.0064 0.1068
Toxoplasma gondii ATPase, AAA family protein 0.0049 0.0028 0.044
Leishmania major DNA polymerase eta, putative 0.0096 0.0082 0.2311
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.006 0.0041 0.1152
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.1698 0.1951 0.2793
Echinococcus granulosus poly adp ribose polymerase 2 0.0258 0.0272 0.0387
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0017 0.0077
Echinococcus granulosus FTZ F1 alpha 0.012 0.011 0.0155
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0019 0.048
Trypanosoma brucei importin beta-1 subunit, putative 0.0066 0.0047 0.1298
Toxoplasma gondii target of rapamycin (TOR), putative 0.0053 0.0033 0.052
Loa Loa (eye worm) DR-78 0.0056 0.0037 0.0187
Schistosoma mansoni tankyrase 0.0035 0.0011 0.0039
Brugia malayi putative neuropeptide receptor NPR1 0.0037 0.0014 0.0072
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0021 0.0097
Loa Loa (eye worm) hypothetical protein 0.0145 0.0139 0.0712
Trypanosoma brucei Heat shock protein 83, putative 0.0071 0.0053 0.1461
Brugia malayi glutaminase DH11.1 0.1705 0.196 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0063 0.0045 0.0227
Giardia lamblia Heat shock protein HSP 90-alpha 0.0071 0.0053 0.1408
Onchocerca volvulus DNA ligase 3 homolog 0.0061 0.0042 0.049
Brugia malayi MH2 domain containing protein 0.0389 0.0425 0.2167
Trypanosoma cruzi heat shock protein, putative 0.0029 0.0005 0.0075
Onchocerca volvulus Bile acid receptor homolog 0.012 0.011 0.1276
Leishmania major phosphatidylinositol 3-kinase, putative 0.0034 0.001 0.0279
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0014 0.0071
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Schistosoma mansoni coup transcription factor 0.012 0.011 0.0437
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0037 0.0014 0.0072
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.012 0.011 0.0109
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0029 0.0005 0.0003
Echinococcus granulosus methyl CpG binding domain protein 2 0.0072 0.0055 0.0076
Onchocerca volvulus 0.0037 0.0014 0.0163
Schistosoma mansoni microtubule-associated protein tau 0.2159 0.2489 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0123 0.0114 0.0582
Brugia malayi nuclear receptor RXR 0.0063 0.0045 0.0227
Echinococcus multilocularis neuropeptide FF receptor 2 0.0037 0.0014 0.0012
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0331 0.0357 1
Brugia malayi Probable citrate synthase, mitochondrial precursor, putative 0.0046 0.0024 0.0124
Onchocerca volvulus 0.0037 0.0014 0.0163
Loa Loa (eye worm) hypothetical protein 0.012 0.011 0.0563
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0014 0.034
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0027 0.0003 0.0014
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0027 0.0003 0.0002
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0636 0.0713 0.1018
Plasmodium vivax replication factor C subunit 1, putative 0.0049 0.0028 0.1219
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.012 0.011 0.0563
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0054 0.0033 0.053
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0017 0.0077
Trypanosoma brucei heat shock protein, putative 0.0071 0.0053 0.1461
Schistosoma mansoni bromodomain containing protein 0.0278 0.0295 0.1178
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.0014 0.005
Trypanosoma brucei heat shock protein 90, putative 0.0071 0.0053 0.1461
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Schistosoma mansoni opsin-like receptor 0.0037 0.0014 0.005
Loa Loa (eye worm) hypothetical protein 0.0063 0.0045 0.0227
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.012 0.011 0.0437
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0014 0.0269
Schistosoma mansoni ap endonuclease 0.006 0.0041 0.0158
Loa Loa (eye worm) MBCTL1 0.0119 0.0109 0.0557
Trypanosoma cruzi PAB1-binding protein , putative 0.0081 0.0065 0.178
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Trypanosoma brucei polo-like protein kinase 0.0113 0.0103 0.2854
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0048 0.0027 0.073
Brugia malayi Latrophilin receptor protein 2 0.017 0.0169 0.0863
Echinococcus granulosus neuropeptide s receptor 0.0037 0.0014 0.0018
Loa Loa (eye worm) glutaminase 0.1705 0.196 1
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0027 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0032 0.0046
Brugia malayi nuclear receptor NHR-88 0.012 0.011 0.0563
Schistosoma mansoni hypothetical protein 0.0037 0.0014 0.005
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0053 0.0033 0.0156
Schistosoma mansoni hypothetical protein 0.1447 0.1659 0.6663
Trichomonas vaginalis heat shock protein, putative 0.0056 0.0036 0.0174
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0171 0.017 0.0677
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0034 0.001 0.0051
Leishmania major citrate synthase, putative 0.0046 0.0024 0.0683
Leishmania major hypothetical protein, conserved 0.0081 0.0065 0.1824
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0037 0.0014 0.0072
Mycobacterium ulcerans hypothetical protein 0.0174 0.0174 0.0249
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.0019 0.0531
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0033 0.0156
Echinococcus granulosus poly (ADP ribose) polymerase 0.0073 0.0056 0.0078
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.001 0.0039
Echinococcus granulosus Nuclear hormone receptor HR96 0.0056 0.0037 0.005
Echinococcus multilocularis expressed protein 0.0027 0.0003 0.0001
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.07 0.0788 0.402
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0027 0.0003 0.0002
Echinococcus multilocularis muscleblind protein 1 0.0145 0.0139 0.0138
Schistosoma mansoni neuropeptide F-like receptor 0.0037 0.0014 0.005
Schistosoma mansoni nuclear hormone receptor 0.0056 0.0037 0.014
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0157 0.0154 0.4302
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0049 0.0028 0.0132
Brugia malayi WGR domain containing protein 0.047 0.0519 0.2647
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Echinococcus granulosus histone lysine methyltransferase setb 0.0171 0.017 0.0241
Onchocerca volvulus Serine\/threonine kinase homolog 0.0113 0.0103 0.1188
Loa Loa (eye worm) acetyltransferase 0.0158 0.0155 0.0793
Echinococcus granulosus retinoic acid receptor rxr beta a 0.012 0.011 0.0155
Schistosoma mansoni inositol monophosphatase 0.0037 0.0014 0.005
Brugia malayi GnHR receptor homolog 0.0037 0.0014 0.0072
Giardia lamblia Grp94/Hsp90 0.0056 0.0036 0.0894
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0027 0.0003 0.0014
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0031 0.0007 0.0025
Onchocerca volvulus Glucosylceramidase homolog 0.0178 0.0178 0.2063
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.006 0.0041 0.0059
Schistosoma mansoni biogenic amine receptor 0.0037 0.0014 0.005
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.012 0.011 0.0155
Schistosoma mansoni methyl-cpg binding protein mbd 0.0072 0.0055 0.0213
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.0537 0.0598 0.305
Echinococcus multilocularis tar DNA binding protein 0.0598 0.0669 0.0667
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0036 0.0171
Loa Loa (eye worm) MH2 domain-containing protein 0.0389 0.0425 0.2167
Trichomonas vaginalis glutaminase, putative 0.1705 0.196 1
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0056 0.0036 0.0971
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0041 0.0156
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0636 0.0713 0.3637
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.047 0.0519 1
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0056 0.0036 0.4438
Echinococcus multilocularis ribosomal protein L19 0.0031 0.0007 0.0006
Echinococcus granulosus G protein coupled receptor 139 0.0037 0.0014 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0047 0.0229
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0027 0.0003 0.0004
Leishmania major heat shock protein, putative 0.0029 0.0005 0.0127
Trypanosoma cruzi target of rapamycin kinase 3 0.0056 0.0036 0.0953
Trichomonas vaginalis bromodomain-containing protein, putative 0.0054 0.0033 0.0159
Toxoplasma gondii ribosomal protein RPL19 0.0031 0.0007 0.0074
Schistosoma mansoni neuropeptide receptor 0.0037 0.0014 0.005
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Echinococcus granulosus fmrfamide receptor 0.0037 0.0014 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0021 0.0098
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0152 0.0148 0.0757
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0025 0.0654
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0041 0.0199
Onchocerca volvulus 0.0054 0.0034 0.0394
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.0014 0.005
Loa Loa (eye worm) histone methyltransferase 0.0042 0.0019 0.0098
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.006 0.0041 0.1123
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0034 0.013
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0287 0.1455
Trypanosoma brucei 60S ribosomal protein L19, putative 0.0031 0.0007 0.0171
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0041 0.6143
Loa Loa (eye worm) hypothetical protein 0.0032 0.0009 0.0043
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0034 0.001 0.0008
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0014 0.006
Brugia malayi Nuclear hormone receptor E75 0.0056 0.0037 0.0187
Trypanosoma brucei heat shock protein, putative 0.0071 0.0053 0.1461
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0014 0.0273
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0014 0.0018
Schistosoma mansoni Tr4/Tr2 (homologue) 0.012 0.011 0.0437
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0014 0.006
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0029 0.0005 0.0088
Schistosoma mansoni importin beta-1 0.0066 0.0047 0.0183
Brugia malayi Dopamine receptor protein 2 0.0037 0.0014 0.0072
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0065 0.0047 0.0908
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0033 0.0156
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0023 0.0104
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0014 0.006
Echinococcus granulosus Protein patched homolog 1 0.0141 0.0136 0.0192
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.008 0.0064 0.0062
Brugia malayi hypothetical protein 0.0081 0.0065 0.0332
Echinococcus multilocularis neuropeptides capa receptor 0.0037 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0144
Schistosoma mansoni GTP-binding protein alpha subunit 0.0027 0.0003 0.0004
Echinococcus multilocularis G-protein coupled receptor, putative 0.0037 0.0014 0.0012
Onchocerca volvulus 0.0096 0.0083 0.0963
Schistosoma mansoni cpg binding protein 0.0138 0.0132 0.0523
Trichomonas vaginalis penicillin-binding protein, putative 0.0205 0.021 0.1059
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.012 0.011 0.0563
Giardia lamblia GTOR 0.0065 0.0047 0.1223
Echinococcus multilocularis neuropeptide receptor 0.0037 0.0014 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-41 0.012 0.011 0.0563
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0041 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.001 0.0039
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0422 0.0464 0.0661
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0065 0.0047 0.0182
Loa Loa (eye worm) PHD-finger family protein 0.0087 0.0072 0.0369
Brugia malayi PHD-finger family protein 0.0116 0.0106 0.054
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0027 0.0003 0.0001
Brugia malayi Pax transcription activation domain interacting protein 0.0049 0.0028 0.0144
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0037 0.0014 0.0018
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0048 0.0027 0.1169
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0333 0.169
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Schistosoma mansoni zinc finger protein 0.0056 0.0037 0.014
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0056 0.0036 0.0186
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0065 0.0047 0.0065
Brugia malayi neuropeptide F receptor 0.0037 0.0014 0.0072
Echinococcus granulosus allatostatin A receptor 0.0037 0.0014 0.0018
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0057 0.0277
Schistosoma mansoni terminal deoxycytidyl transferase 0.0041 0.0019 0.0069
Brugia malayi photoreceptor-specific nuclear receptor 0.012 0.011 0.0563
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0019 0.048
Entamoeba histolytica hypothetical protein 0.0035 0.0011 0.0221
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0032 0.0043
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0119 0.0109 0.0107
Trichomonas vaginalis heat shock protein, putative 0.0056 0.0036 0.0174
Loa Loa (eye worm) tnks protein 0.0035 0.0011 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Echinococcus multilocularis ecdysone induced protein 78C 0.012 0.011 0.0109
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0048 0.0027 0.0025
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0636 0.0713 0.2858
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0049 0.0028 0.2799
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0031 0.0007 0.016
Schistosoma mansoni endoplasmin 0.0071 0.0053 0.0207
Trichomonas vaginalis importin beta-1, putative 0.0053 0.0033 0.0156
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0037 0.0014 0.0012
Plasmodium vivax endoplasmin, putative 0.0071 0.0053 0.2427
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0014 0.006
Schistosoma mansoni tar DNA-binding protein 0.0598 0.0669 0.2681
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0054 0.0033 0.0159
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0178 0.09
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.0064 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0017 0.0077
Entamoeba histolytica hypothetical protein 0.0033 0.0009 0.0182
Entamoeba histolytica hypothetical protein 0.019 0.0192 0.3711
Loa Loa (eye worm) hypothetical protein 0.0162 0.016 0.0815
Trichomonas vaginalis D-aminoacylase, putative 0.0205 0.021 0.1059
Leishmania major mitochondrial DNA polymerase beta 0.0331 0.0357 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0007 0.0037
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.006 0.0041 0.0039
Echinococcus multilocularis neuropeptide Y receptor 0.0037 0.0014 0.0012
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0005 0.0012
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0014 0.0018
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0027 0.0003 0.0014
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.0064 0.1068
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0029 0.0005 0.0004
Schistosoma mansoni heat shock protein 0.0029 0.0005 0.0011
Schistosoma mansoni nuclear receptor nhr-48 0.0056 0.0037 0.014
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0034 0.001 0.0227
Echinococcus granulosus g-protein coupled receptor 0.0037 0.0014 0.0018
Loa Loa (eye worm) RNA binding protein 0.0598 0.0669 0.3412
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0034 0.0011 0.0009
Echinococcus granulosus fetal alzheimer antigen falz 0.0102 0.009 0.0126
Brugia malayi DKFZp564C0469 protein 0.0049 0.0028 0.0144
Loa Loa (eye worm) endoplasmin 0.0071 0.0053 0.0271
Trypanosoma brucei heat shock protein, putative 0.0071 0.0053 0.1461
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0021 0.0098
Giardia lamblia Replication factor C, subunit 1 0.0049 0.0028 0.0642
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.012 0.011 0.0155
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0056 0.0037 0.0035
Echinococcus granulosus WGR domain containing protein 0.0146 0.0141 0.0199
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0636 0.0713 0.0711
Echinococcus multilocularis tumor protein p63 0.037 0.0403 0.0401
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.012 0.011 0.0109
Onchocerca volvulus 0.0037 0.0014 0.0163
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0027 0.0003 0.0002
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0048 0.0027 0.061
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0056 0.0037 0.0423
Loa Loa (eye worm) G protein alpha subunit 3 0.0027 0.0003 0.0014
Echinococcus multilocularis beta LACTamase domain containing family member 0.0205 0.021 0.0208
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0014 0.0018
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.012 0.011 0.0437
Trypanosoma brucei 60S ribosomal protein L19, putative 0.0031 0.0007 0.0171
Trichomonas vaginalis esterase, putative 0.0205 0.021 0.1059
Loa Loa (eye worm) phosphatidylinositol 3 0.0034 0.001 0.0051
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0171 0.017 0.0677
Entamoeba histolytica deoxycytidyl transferase, putative 0.0041 0.0019 0.0365
Schistosoma mansoni nuclear hormone receptor 0.0056 0.0037 0.014
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0103 0.0513
Brugia malayi Calcitonin receptor-like protein seb-1 0.0537 0.0598 0.305
Echinococcus multilocularis neuropeptide s receptor 0.0037 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0258 0.0272 0.1387
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.006 0.0041 0.1105
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0042 0.0019 0.0018
Loa Loa (eye worm) melatonin receptor type 1A 0.0037 0.0014 0.0072
Treponema pallidum DNA ligase (lig) 0.0049 0.0028 0.0763
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0037 0.0014 0.0012
Echinococcus multilocularis G protein coupled receptor 139 0.0037 0.0014 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-3 0.012 0.011 0.0563
Leishmania major GTP-binding protein, putative 0.0048 0.0027 0.076
Brugia malayi beta-lactamase family protein 0.0205 0.021 0.107
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0027 0.0002 0.0001
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0056 0.0037 0.0035
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0037 0.0014 0.005
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.006 0.0041 0.021
Schistosoma mansoni transcription factor LCR-F1 0.019 0.0192 0.0767
Schistosoma mansoni hypothetical protein 0.017 0.0169 0.0673
Treponema pallidum exodeoxyribonuclease (exoA) 0.006 0.0041 0.1156
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0113 0.0103 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0157 0.0154 0.4283
Loa Loa (eye worm) hypothetical protein 0.0063 0.0045 0.0227
Entamoeba histolytica hypothetical protein 0.019 0.0192 0.3711
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0021 0.0098
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0056 0.0036 0.005
Onchocerca volvulus 0.0037 0.0014 0.0163
Brugia malayi putative neuropeptide receptor 0.0037 0.0014 0.0072
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0027 0.0003 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Mycobacterium tuberculosis Probable hydrolase 0.0205 0.021 0.03
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0037 0.0014 0.0072
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0027 0.0003 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0014 0.0018
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0049 0.0028 0.004
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Echinococcus granulosus chromobox protein 1 0.0074 0.0057 0.0079
Schistosoma mansoni neuropeptide F-like receptor 0.0037 0.0014 0.005
Loa Loa (eye worm) hypothetical protein 0.008 0.0064 0.0328
Onchocerca volvulus 0.0037 0.0014 0.0163
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0014 0.0012
Schistosoma mansoni chromosome transmission fidelity factor 0.0049 0.0028 0.0106
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0054 0.0033 0.1468
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0034 0.001 0.0033
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0104 0.0092 0.1067
Schistosoma mansoni neuropeptide f receptor 76f 0.0037 0.0014 0.005
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0037 0.0014 0.005
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0333 0.169
Brugia malayi hypothetical protein 0.019 0.0192 0.0982
Brugia malayi Glycosyl hydrolases family 31 protein 0.0167 0.0165 0.0844
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.012 0.011 0.0563
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0037 0.0014 0.0012
Echinococcus multilocularis heat shock protein 0.0071 0.0053 0.0051
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0185 0.0187 0.0953
Echinococcus multilocularis ribosomal protein L19 0.0031 0.0007 0.0006
Echinococcus multilocularis neuropeptide Y receptor 0.0037 0.0014 0.0012
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0048 0.0027 0.3889
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0287 0.1455
Trypanosoma cruzi PAB1-binding protein , putative 0.0081 0.0065 0.178
Plasmodium falciparum heat shock protein 90 0.0071 0.0053 0.8075
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0031 0.0007 0.0151
Schistosoma mansoni hypothetical protein 0.07 0.0788 0.316
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Echinococcus multilocularis Niemann Pick C1 protein 0.0471 0.052 0.0519
Brugia malayi Dopamine receptor protein 1 0.0037 0.0014 0.0072
Trypanosoma cruzi citrate synthase, putative 0.0046 0.0024 0.0633
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.012 0.011 0.0563
Echinococcus granulosus sex peptide receptor 0.0037 0.0014 0.0018
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0014 0.006
Echinococcus multilocularis thyroid hormone receptor alpha 0.0406 0.0445 0.0443
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0027 0.0003 0.0014
Mycobacterium tuberculosis Conserved protein 0.0205 0.021 0.03
Brugia malayi Bromodomain containing protein 0.0165 0.0164 0.0835
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Onchocerca volvulus 0.0037 0.0014 0.0163
Echinococcus multilocularis g protein coupled receptor 0.0037 0.0014 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0047 0.0229
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0014 0.0012
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.012 0.011 0.0155
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.033 0.0355 0.6851
Onchocerca volvulus Tankyrase homolog 0.0035 0.0011 0.0132
Echinococcus granulosus poly ADP ribose polymerase 1 0.047 0.0519 0.074
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.006 0.0041 0.5391
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0048 0.0027 0.0711
Mycobacterium ulcerans thymidine phosphorylase 0.6015 0.6988 1
Toxoplasma gondii LsmAD domain-containing protein 0.0081 0.0065 0.1084
Onchocerca volvulus 0.0027 0.0003 0.0031
Schistosoma mansoni amine GPCR 0.0037 0.0014 0.005
Loa Loa (eye worm) hypothetical protein 0.0173 0.0173 0.0883
Echinococcus granulosus poly (ADP ribose) polymerase 0.0146 0.0141 0.0199
Schistosoma mansoni hypothetical protein 0.017 0.0169 0.0673
Echinococcus granulosus serine protein kinase ATM 0.0033 0.0009 0.0011
Brugia malayi CHD4 protein 0.0027 0.0002 0.0012
Schistosoma mansoni neuropeptide receptor 0.0037 0.0014 0.005
Brugia malayi Pre-SET motif family protein 0.0674 0.0757 0.3861
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0537 0.0598 0.305
Onchocerca volvulus 0.0037 0.0014 0.0163
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0037 0.0014 0.005
Brugia malayi acetyltransferase, GNAT family protein 0.0158 0.0155 0.0793
Brugia malayi Probable ClpP-like protease 0.008 0.0064 0.0328
Echinococcus granulosus mixed lineage leukemia protein mll 0.0034 0.0011 0.0013
Brugia malayi hypothetical protein 0.0155 0.0151 0.0771
Schistosoma mansoni amine GPCR 0.0037 0.0014 0.005
Plasmodium vivax heat shock protein 90, putative 0.0029 0.0005 0.0076
Toxoplasma gondii HEAT repeat-containing protein 0.0066 0.0047 0.0774
Onchocerca volvulus 0.012 0.011 0.1276
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0027 0.0003 0.0002
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.008 0.0064 0.2961
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0014 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.006 0.0041 0.1105
Treponema pallidum heat shock protein 90 0.0056 0.0036 0.1011
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Schistosoma mansoni hypothetical protein 0.019 0.0192 0.0767
Echinococcus granulosus neuropeptide receptor A26 0.0037 0.0014 0.0018
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Brugia malayi chromobox protein homolog 3 0.0041 0.0019 0.0096
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0205 0.021 0.03
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0027 0.0003 0.0014
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0041 0.0058
Echinococcus multilocularis polycomb protein SCMH1 0.0104 0.0092 0.0091
Trypanosoma brucei heat shock protein, putative 0.0071 0.0053 0.1461
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0027 0.0003 0.0004
Trichomonas vaginalis endoplasmin, putative 0.0043 0.0021 0.0097
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0271 0.0287 0.1465
Loa Loa (eye worm) hypothetical protein 0.0299 0.0319 0.1628
Brugia malayi Heterochromatin protein 1 0.0074 0.0057 0.0289
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0287 0.0305 0.0303
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0036 0.0013 0.0011
Echinococcus multilocularis serotonin receptor 0.0037 0.0014 0.0012
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0102 0.009 0.0088
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0048 0.0027 0.0138
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0027 0.0003 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.012 0.011 0.0563
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0037 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trypanosoma brucei glucosidase, putative 0.0037 0.0014 0.036
Echinococcus granulosus geminin 0.1447 0.1659 0.2372
Brugia malayi nuclear receptor NHR-88 0.0056 0.0037 0.0187
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0171 0.017 0.0168
Echinococcus multilocularis tankyrase 0.0035 0.0011 0.001
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0017 0.0313
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0014
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.008 0.0064 1
Brugia malayi Serotonin receptor 0.0037 0.0014 0.0072
Giardia lamblia Kinase, PLK 0.0113 0.0103 0.2929
Loa Loa (eye worm) neuropeptide F receptor 0.0037 0.0014 0.0072
Brugia malayi nuclear hormone receptor family member odr-7 0.0056 0.0037 0.0187
Loa Loa (eye worm) hypothetical protein 0.012 0.011 0.0563
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0034 0.0011 0.0009
Schistosoma mansoni sex comb on midleg homolog 0.0104 0.0092 0.0364
Onchocerca volvulus 0.0049 0.0028 0.0326
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trypanosoma cruzi importin beta-1 subunit, putative 0.0053 0.0033 0.0872
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0065 0.0047 0.1291
Loa Loa (eye worm) TYRA-2 protein 0.0037 0.0014 0.0072
Brugia malayi hypothetical protein 0.0052 0.0032 0.0162
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0014 0.006
Loa Loa (eye worm) hypothetical protein 0.0205 0.021 0.107
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0037 0.0014 0.005
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0019 0.0097
Schistosoma mansoni myelin transcription factor 1 myt1 0.0119 0.0109 0.0432
Mycobacterium tuberculosis Conserved protein 0.0205 0.021 0.03
Loa Loa (eye worm) hypothetical protein 0.0119 0.0109 0.0557
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.047 0.0519 0.0517
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.1698 0.1951 1
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Entamoeba histolytica 60S ribosomal protein L19, putative 0.0031 0.0007 0.014
Brugia malayi CXXC zinc finger family protein 0.0123 0.0114 0.0582
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0014 0.0397
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0158 0.0155 0.0154
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0063 0.0045 0.0061
Mycobacterium tuberculosis Conserved protein 0.0205 0.021 0.03
Echinococcus granulosus Niemann Pick C1 protein 0.033 0.0355 0.0506
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0065 0.0047 0.132
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0102 0.009 0.0355
Leishmania major citrate synthase, putative 0.0046 0.0024 0.0683
Loa Loa (eye worm) hypothetical protein 0.012 0.011 0.0563
Schistosoma mansoni topbp1 0.0049 0.0028 0.0106
Trypanosoma brucei poly(adp-ribose) polymerase 0.0258 0.0272 0.7608
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0037 0.0014 0.005
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0014 0.0061
Trypanosoma brucei PAB1-binding protein , putative 0.0081 0.0065 0.1797
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0027 0.0003 0.0001
Loa Loa (eye worm) glutaminase 2 0.1705 0.196 1
Schistosoma mansoni hypothetical protein 0.0136 0.013 0.0515
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0028 0.0132
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0014 0.0061
Entamoeba histolytica hypothetical protein 0.019 0.0192 0.3711
Schistosoma mansoni DNA ligase IV 0.0049 0.0028 0.0106
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0033 0.0009 0.0031
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.001 0.0049
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0264 0.0279 0.1115
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0014 0.0269
Schistosoma mansoni biogenic amine receptor 0.0037 0.0014 0.005
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0027 0.0003 0.0001
Schistosoma mansoni hypothetical protein 0.0367 0.0399 0.1599
Trichomonas vaginalis helicase, putative 0.0028 0.0003 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0016 0.0069
Loa Loa (eye worm) hypothetical protein 0.0029 0.0004 0.0022
Echinococcus multilocularis importin subunit beta 1 0.0066 0.0047 0.0046
Echinococcus granulosus hypothetical protein 0.0037 0.0014 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0005 0.0013
Brugia malayi MH2 domain containing protein 0.0027 0.0002 0.0009
Echinococcus granulosus neuropeptide FF receptor 2 0.0037 0.0014 0.0018
Schistosoma mansoni steroid hormone receptor ad4bp 0.012 0.011 0.0437
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0065 0.0047 0.1291
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0019 0.0085
Loa Loa (eye worm) bromodomain containing protein 0.0078 0.0062 0.0317
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0019 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-25 0.012 0.011 0.0563
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.001 0.0014
Schistosoma mansoni chromobox protein 0.0074 0.0057 0.0221
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0036 0.0171
Echinococcus multilocularis neuropeptide receptor A26 0.0037 0.0014 0.0012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0636 0.0713 0.2858
Brugia malayi hypothetical protein 0.0056 0.0037 0.0187
Echinococcus multilocularis neuropeptides capa receptor 0.0037 0.0014 0.0012
Brugia malayi hypothetical protein 0.0027 0.0003 0.0014
Schistosoma mansoni thyroid hormone receptor 0.0406 0.0445 0.1781
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Brugia malayi 60S ribosomal protein L19 0.0031 0.0007 0.0037
Onchocerca volvulus 0.0056 0.0037 0.0423
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0027 0.0003 0.0004
Echinococcus granulosus 7TM GPCR rhodopsin 0.0037 0.0014 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0021 0.0098
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0037 0.0014 0.0012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0017 0.0077
Onchocerca volvulus 0.0037 0.0014 0.0163
Echinococcus multilocularis expressed conserved protein 0.031 0.0332 0.033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0024 0.0112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0021 0.0098
Loa Loa (eye worm) nuclear hormone receptor 0.0056 0.0037 0.0187
Loa Loa (eye worm) hypothetical protein 0.0054 0.0034 0.0174
Schistosoma mansoni heat shock protein 0.0071 0.0053 0.0207
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0205 0.021 0.03
Brugia malayi RNA binding protein 0.0598 0.0669 0.3412
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0037 0.0014 0.0072
Echinococcus granulosus ribosomal protein L19 0.0031 0.0007 0.0008
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0041 0.0156
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0065 0.0047 0.0045
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0014 0.0012
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0422 0.0464 0.0462
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0037 0.0014 0.005
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0037 0.0014 0.005
Echinococcus multilocularis histone acetyltransferase MYST2 0.0119 0.0109 0.0107
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0103 0.0513
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Plasmodium vivax SET domain protein, putative 0.0099 0.0086 0.4027
Plasmodium vivax hypothetical protein, conserved 0.0205 0.021 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0034 0.0011 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0014 0.0012
Mycobacterium ulcerans lipase LipD 0.0205 0.021 0.03
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.012 0.011 0.0437
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0049 0.0028 0.0144
Loa Loa (eye worm) G-protein coupled receptor 0.0037 0.0014 0.0072
Loa Loa (eye worm) MH1 domain-containing protein 0.0027 0.0002 0.0009
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0049 0.0028 0.0144
Entamoeba histolytica Ran family GTPase 0.0048 0.0027 0.0523
Loa Loa (eye worm) phosphatidylinositol 3 0.0065 0.0047 0.024
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.008 0.0064 0.0089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0016 0.0069
Loa Loa (eye worm) hypothetical protein 0.0205 0.021 0.107
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0037 0.0014 0.0018
Trypanosoma cruzi heat shock protein 85, putative 0.0071 0.0053 0.1443
Echinococcus multilocularis citrate synthase 0.0046 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0139 0.0196
Echinococcus granulosus g protein coupled receptor 0.0037 0.0014 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0333 0.169
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Brugia malayi RNA recognition motif domain containing protein 0.0598 0.0669 0.3412
Brugia malayi G protein-coupled receptor 0.0037 0.0014 0.0072
Schistosoma mansoni hypothetical protein 0.0037 0.0014 0.005
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trypanosoma brucei hypothetical protein, conserved 0.0205 0.021 0.586
Brugia malayi MH1 domain containing protein 0.0027 0.0002 0.0009
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0056 0.0037 0.0035
Loa Loa (eye worm) hypothetical protein 0.012 0.011 0.0563
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.006 0.0041 0.104
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0031 0.0007 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0028 0.0132
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Brugia malayi Steroid receptor seven-up type 2 0.012 0.011 0.0563
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0152 0.0148 0.0212
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0027 0.0003 0.0001
Brugia malayi steroid hormone receptor 0.012 0.011 0.0563
Schistosoma mansoni topbp1 0.0049 0.0028 0.0106
Brugia malayi Tachykinin-like peptides receptor 99D 0.0037 0.0014 0.0072
Entamoeba histolytica heat shock protein 90, putative 0.0071 0.0053 0.1024
Echinococcus granulosus nuclear receptor nhr 48 0.0056 0.0037 0.005
Mycobacterium ulcerans hypothetical protein 0.0205 0.021 0.03
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0331 0.0357 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0014 0.0012
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0034 0.001 0.0279
Echinococcus granulosus dna polymerase kappa 0.0041 0.0019 0.0025
Brugia malayi hypothetical protein 0.0049 0.0028 0.0144
Brugia malayi WGR domain containing protein 0.0258 0.0272 0.1387
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.006 0.0041 0.0059
Echinococcus granulosus nuclear receptor 2DBD gamma 0.012 0.011 0.0155
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0027 0.0002 0.0001
Schistosoma mansoni cpg binding protein 0.0123 0.0114 0.0452
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0019 0.0027
Echinococcus granulosus GPCR family 2 0.017 0.0169 0.024
Echinococcus multilocularis g protein coupled receptor 0.0037 0.0014 0.0012
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0019 0.0218
Echinococcus granulosus expressed protein 0.0027 0.0003 0.0001
Loa Loa (eye worm) Smad1 0.0027 0.0002 0.0009
Echinococcus granulosus heat shock protein 90 0.0071 0.0053 0.0074
Plasmodium vivax importin-beta 2, putative 0.0066 0.0047 0.2146
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0063 0.0045 0.0172
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0027 0.0003 0.0014
Echinococcus granulosus ribosomal protein L19 0.0031 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0113 0.0103 0.0145
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0004 0.008
Echinococcus granulosus Niemann Pick C1 protein 0.0471 0.052 0.0742
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.017 0.0169 0.024
Echinococcus granulosus zinc finger protein 0.0093 0.008 0.0111
Schistosoma mansoni nuclear receptor 0.0056 0.0037 0.014
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus granulosus alpha 1A adrenergic receptor 0.0037 0.0014 0.0018
Leishmania major importin beta-1 subunit, putative 0.0053 0.0033 0.0921
Echinococcus granulosus tachykinin peptides receptor 99D 0.0037 0.0014 0.0018
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0049 0.0028 0.0759
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0049 0.0028 0.0132
Brugia malayi ecdysone receptor 0.0056 0.0037 0.0187
Mycobacterium tuberculosis Probable lipase LipE 0.0205 0.021 0.03
Echinococcus multilocularis cpg binding protein 0.0138 0.0132 0.013
Loa Loa (eye worm) hypothetical protein 0.0145 0.0139 0.0712
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0014 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0036 0.0171
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0037 0.0014 0.0072
Echinococcus granulosus citrate synthase 0.0046 0.0024 0.0032
Schistosoma mansoni chromobox protein 0.0074 0.0057 0.0221
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0037 0.0014 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Schistosoma mansoni bromodomain containing protein 0.0029 0.0004 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Trichomonas vaginalis conserved hypothetical protein 0.0141 0.0136 0.0682
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Brugia malayi Serotonin receptor 0.0037 0.0014 0.0072
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0014 0.034
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Schistosoma mansoni hypothetical protein 0.0136 0.013 0.0515
Echinococcus granulosus biogenic amine 5HT receptor 0.0037 0.0014 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Echinococcus granulosus beta LACTamase domain containing family member 0.0205 0.021 0.0298
Brugia malayi hypothetical protein 0.0049 0.0028 0.0144
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0028 0.074
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0025 0.0654
Brugia malayi nuclear hormone receptor family member nhr-6 0.0056 0.0037 0.0187
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0048 0.0027 0.0711
Mycobacterium ulcerans beta-lactamase 0.0205 0.021 0.03
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0037 0.0014 0.005
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0037 0.0014 0.0072
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0104 0.0092 0.0364
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Brugia malayi sulfakinin receptor protein 0.0037 0.0014 0.0072
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0027 0.0003 0.0014
Trypanosoma cruzi polo-like protein kinase, putative 0.0113 0.0103 0.284
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Echinococcus granulosus tm gpcr rhodopsin 0.0037 0.0014 0.0018
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.012 0.011 0.0563
Echinococcus multilocularis dro:myosuppressin receptor 0.0037 0.0014 0.0012
Trichomonas vaginalis penicillin-binding protein, putative 0.0205 0.021 0.1059
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0152 0.0148 0.0209
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.001
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0113 0.0103 0.0524
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.0014 0.005
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0111 0.01 0.0396
Echinococcus multilocularis snurportin 1 0.07 0.0788 0.0786
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.006 0.0041 0.0056
Echinococcus multilocularis nibrin 0.0049 0.0028 0.0026
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0054 0.0033 0.053
Loa Loa (eye worm) heat shock protein 90 0.0071 0.0053 0.0271
Brugia malayi Nuclear hormone receptor E75 0.0056 0.0037 0.0187
Trichomonas vaginalis D-aminoacylase, putative 0.0205 0.021 0.1059
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0017 0.2327
Plasmodium vivax 60S ribosomal protein L19, putative 0.0031 0.0007 0.0207
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Plasmodium vivax citrate synthase, mitochondrial precursor, putative 0.0046 0.0024 0.1035
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0065 0.0047 0.1274
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0287 0.1455
Trypanosoma cruzi FHA domain containing protein, putative 0.0049 0.0028 0.074
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0037 0.0014 0.0012
Echinococcus multilocularis microtubule associated protein 2 0.2159 0.2489 0.2488
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0056 0.0037 0.0187
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0049 0.0028 0.074
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0041 0.0056
Schistosoma mansoni amine GPCR 0.0037 0.0014 0.005
Echinococcus granulosus expressed conserved protein 0.031 0.0332 0.0473
Loa Loa (eye worm) hypothetical protein 0.0205 0.021 0.107
Echinococcus granulosus neuropeptide receptor 0.0037 0.0014 0.0018
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.019 0.0192 0.0191
Echinococcus granulosus neuropeptide receptor 0.0037 0.0014 0.0018
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Plasmodium falciparum ataxin-2 like protein, putative 0.0081 0.0065 1
Trypanosoma cruzi hypothetical protein, conserved 0.0205 0.021 0.5852
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0027 0.0003 0.0014
Leishmania major hypothetical protein, conserved 0.0065 0.0046 0.1293
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0103 0.0406
Brugia malayi nuclear receptor NHR-67 0.0056 0.0037 0.0187
Schistosoma mansoni peptidase Clp (S14 family) 0.008 0.0064 0.0251
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.012 0.011 0.0109
Loa Loa (eye worm) mbt repeat family protein 0.0104 0.0092 0.0471
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0065 0.0047 0.1274
Brugia malayi Nuclear hormone receptor family member nhr-25 0.012 0.011 0.0563
Entamoeba histolytica zinc finger protein, putative 0.0035 0.0011 0.0221
Mycobacterium ulcerans esterase/lipase LipP 0.0205 0.021 0.03
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0041 0.0058
Trypanosoma cruzi DNA repair protein, putative 0.0061 0.0042 0.1139
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trypanosoma brucei heat shock protein, putative 0.0071 0.0053 0.1461
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0674 0.0757 0.3861
Toxoplasma gondii ABC1 family protein 0.0205 0.021 0.3606
Loa Loa (eye worm) citrate synthase 0.0046 0.0024 0.0124
Brugia malayi G protein-coupled receptor F59B2.13 0.0037 0.0014 0.0072
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0065 0.0047 0.0908
Echinococcus multilocularis endoplasmin 0.0056 0.0036 0.0035
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0037 0.0988
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0014 0.002
Mycobacterium ulcerans glutaminase 0.1705 0.196 0.2805
Schistosoma mansoni hypothetical protein 0.0875 0.0991 0.3977
Brugia malayi Melatonin receptor type 1A 0.0037 0.0014 0.0072
Onchocerca volvulus 0.0032 0.0009 0.0098
Trypanosoma cruzi Heat shock protein 83, putative 0.0071 0.0053 0.1443
Plasmodium falciparum heat shock protein 90, putative 0.0029 0.0005 0.0251
Onchocerca volvulus Protein ultraspiracle homolog 0.012 0.011 0.1276
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.001 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0004 0.008
Echinococcus granulosus poly (ADP ribose) polymerase 0.0073 0.0056 0.0078
Schistosoma mansoni methyl-cpg binding protein mbd 0.0072 0.0055 0.0213
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0037 0.0014 0.0012
Echinococcus multilocularis chromobox protein 1 0.0074 0.0057 0.0055
Brugia malayi Smad1 0.0027 0.0002 0.0009
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0014 0.0346
Trypanosoma cruzi DNA polymerase eta, putative 0.0067 0.0049 0.1335
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trypanosoma brucei importin beta-1 subunit, putative 0.0066 0.0047 0.1298
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0037 0.0014 0.0012
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0033 0.0009 0.0212
Toxoplasma gondii heat shock protein 90, putative 0.0071 0.0053 0.0875
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0311 0.0333 0.6422
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0027 0.0003 0.0014
Schistosoma mansoni ran 0.0048 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Leishmania major DNA polymerase kappa, putative 0.0041 0.0019 0.0531
Loa Loa (eye worm) hypothetical protein 0.012 0.011 0.0563
Trypanosoma cruzi heat shock protein 85, putative 0.0056 0.0036 0.0971
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0042 0.0019 0.0025
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0108 0.0097 0.0095
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0178 0.09
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0065 0.0047 0.132
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0041 0.1846
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0027 0.0003 0.0001
Treponema pallidum fructose-bisphosphate aldolase 0.0311 0.0333 1
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0027 0.0003 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0033 0.0156
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0057 0.0277
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Trypanosoma cruzi heat shock protein 85, putative 0.0071 0.0053 0.1443
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0028 0.0132
Schistosoma mansoni thyroid hormone receptor 0.0406 0.0445 0.1781
Plasmodium falciparum 60S ribosomal protein L19 0.0031 0.0007 0.0687
Echinococcus granulosus dnaJ subfamily B 0.0875 0.0991 0.1416
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0004 0.008
Echinococcus multilocularis protein patched 0.0141 0.0136 0.0134
Loa Loa (eye worm) hypothetical protein 0.012 0.011 0.0563
Echinococcus multilocularis somatostatin receptor 0.0037 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Loa Loa (eye worm) steroid hormone receptor 0.012 0.011 0.0563
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0027 0.0003 0.0002
Leishmania major hypothetical protein, conserved 0.0205 0.021 0.5874
Echinococcus granulosus endoplasmin 0.0056 0.0036 0.005
Toxoplasma gondii FATC domain-containing protein 0.0033 0.0009 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Echinococcus granulosus biogenic amine 5HT receptor 0.0037 0.0014 0.0018
Echinococcus granulosus tankyrase 0.0035 0.0011 0.0014
Echinococcus granulosus peptide allatostatin:somatostatin 0.0037 0.0014 0.0018
Trichomonas vaginalis replication factor C large subunit, putative 0.0049 0.0028 0.0132
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0033 0.0009 0.0232
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0027 0.0003 0.0004
Brugia malayi Endoplasmin precursor 0.0071 0.0053 0.0271
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.017 0.0169 0.0167
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0019 0.05
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0056 0.0037 0.005
Toxoplasma gondii Hsp90 domain-containing protein 0.0029 0.0005 0.0027
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0034 0.0011 0.0035
Brugia malayi ecdysteroid receptor 0.012 0.011 0.0563
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0036 0.0171
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0335 0.0361 0.1446
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0033 0.0156
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0027 0.0003 0.0014
Trypanosoma cruzi heat shock protein 85, putative 0.0071 0.0053 0.1443
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0014 0.0346
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0023 0.0104
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.012 0.011 0.0563
Entamoeba histolytica hypothetical protein 0.0035 0.0011 0.0221
Echinococcus multilocularis lysosomal alpha glucosidase 0.0167 0.0165 0.0164
Onchocerca volvulus 0.0205 0.021 0.2424
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0028 0.074
Echinococcus granulosus serotonin receptor 0.0037 0.0014 0.0018
Toxoplasma gondii exonuclease III APE 0.006 0.0041 0.0666
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0027 0.0003 0.0002
Entamoeba histolytica hypothetical protein 0.0035 0.0011 0.0221
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0014
Onchocerca volvulus 0.0037 0.0014 0.0163
Echinococcus granulosus GTP binding nuclear protein Ran 0.0048 0.0027 0.0036
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0027 0.0003 0.0004
Brugia malayi Hsp90 protein 0.0029 0.0005 0.0023
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0028 0.0003 0.0015
Schistosoma mansoni sex comb on midleg homolog 0.0104 0.0092 0.0364
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0019 0.0083
Brugia malayi G-protein alpha subunit 0.0027 0.0003 0.0014
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1308 0.1497 0.2142
Brugia malayi hypothetical protein 0.0056 0.0037 0.0187
Schistosoma mansoni hypothetical protein 0.0136 0.013 0.0515
Mycobacterium tuberculosis Probable esterase LipL 0.0205 0.021 0.03
Echinococcus multilocularis fmrfamide receptor 0.0037 0.0014 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0287 0.1455
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Onchocerca volvulus 0.0037 0.0014 0.0163
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0028 0.0132
Leishmania major hypothetical protein, conserved 0.0061 0.0042 0.1186
Loa Loa (eye worm) hypothetical protein 0.0063 0.0045 0.0227
Toxoplasma gondii heat shock protein 75, putative 0.0029 0.0005 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Trypanosoma brucei heat shock protein, putative 0.0071 0.0053 0.1461
Brugia malayi Nuclear hormone receptor family member nhr-14 0.012 0.011 0.0563
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.017 0.0169 0.024
Echinococcus granulosus neuropeptides capa receptor 0.0037 0.0014 0.0018
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Echinococcus multilocularis g-protein coupled receptor 0.0037 0.0014 0.0012
Trypanosoma cruzi heat shock protein 90, putative 0.0056 0.0036 0.0971
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Schistosoma mansoni hypothetical protein 0.0136 0.013 0.0515
Schistosoma mansoni hypothetical protein 0.0065 0.0046 0.0179
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0223 0.0231 0.0922
Schistosoma mansoni adenoreceptor 0.0037 0.0014 0.005
Giardia lamblia DINP protein human, muc B family 0.0041 0.0019 0.0359
Echinococcus granulosus Nuclear hormone receptor HR96 0.0056 0.0037 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.012 0.011 0.0109
Schistosoma mansoni hypothetical protein 0.0037 0.0014 0.005
Echinococcus granulosus chromobox protein 1 0.0074 0.0057 0.0079
Brugia malayi ImpB/MucB/SamB family protein 0.0096 0.0082 0.0421
Onchocerca volvulus 0.0037 0.0014 0.0163
Schistosoma mansoni myosin xvIII 0.0037 0.0014 0.005
Trypanosoma cruzi citrate synthase, putative 0.0046 0.0024 0.0633
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0014 0.0018
Loa Loa (eye worm) hypothetical protein 0.0191 0.0193 0.0986
Loa Loa (eye worm) hypothetical protein 0.0061 0.0042 0.0216
Echinococcus granulosus thymidine phosphorylase 0.6015 0.6988 1
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Entamoeba histolytica hypothetical protein 0.0073 0.0056 0.1078
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Onchocerca volvulus 0.0155 0.0151 0.1747
Entamoeba histolytica exodeoxyribonuclease III, putative 0.006 0.0041 0.0793
Schistosoma mansoni tar DNA-binding protein 0.0598 0.0669 0.2681
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0034 0.001 0.0012
Schistosoma mansoni hypothetical protein 0.017 0.0169 0.0673
Trypanosoma brucei DNA polymerase eta, putative 0.0096 0.0082 0.2285
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0041 0.0019 0.0025
Onchocerca volvulus 0.0037 0.0014 0.0163
Echinococcus granulosus tm gpcr rhodopsin 0.0037 0.0014 0.0018
Leishmania major DNA repair protein, putative 0.0061 0.0042 0.1186
Echinococcus multilocularis chromobox protein 1 0.0074 0.0057 0.0055
Plasmodium falciparum importin beta, putative 0.0066 0.0047 0.7142
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0056 0.0036 0.0052
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0103 0.0513
Echinococcus multilocularis orexin receptor type 2 0.0037 0.0014 0.0012
Brugia malayi G-protein coupled receptor 0.0037 0.0014 0.0072
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0037 0.0014 0.0018
Echinococcus multilocularis FTZ F1 alpha 0.012 0.011 0.0109
Echinococcus granulosus poly (ADP ribose) polymerase 0.0073 0.0056 0.0078
Schistosoma mansoni alpha-glucosidase 0.0144 0.0138 0.0549
Onchocerca volvulus 0.0205 0.021 0.2424
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0009 0.0037
Loa Loa (eye worm) hypothetical protein 0.0081 0.0065 0.0332
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0049 0.0028 0.0132
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0636 0.0713 0.1018
Plasmodium falciparum heat shock protein 90, putative 0.0029 0.0005 0.0251
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0019 0.0017
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0027 0.0003 0.0014
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0031 0.0007 0.0151
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0027 0.0002 0.0003
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0027 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.017 0.0169 0.0863
Trichomonas vaginalis ran, putative 0.0048 0.0027 0.0127
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0014 0.006
Loa Loa (eye worm) MH2 domain-containing protein 0.0027 0.0002 0.0009
Trypanosoma cruzi heat shock protein 90, putative 0.0071 0.0053 0.1443
Onchocerca volvulus 0.0205 0.021 0.2424
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.019 0.0957
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0205 0.021 0.107
Schistosoma mansoni nuclear hormone receptor 0.012 0.011 0.0437
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0019 0.05
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.0025 0.0673
Brugia malayi ORL1-like opioid receptor 0.0037 0.0014 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Echinococcus granulosus nibrin 0.0049 0.0028 0.0038
Onchocerca volvulus 0.0037 0.0014 0.0163
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0027 0.0003 0.0004
Schistosoma mansoni opsin-like receptor 0.0037 0.0014 0.005
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.0064 0.0092
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.017 0.0169 0.0863
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0014 0.006
Mycobacterium tuberculosis Probable lipase LipD 0.0205 0.021 0.03
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0024 0.0112
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0014
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0014 0.0018
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0036 0.0173
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0144
Schistosoma mansoni ran 0.0048 0.0027 0.0102
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0014 0.0391
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0053 0.0033 0.0156
Trypanosoma cruzi ISWI complex protein 0.0065 0.0046 0.1246
Plasmodium falciparum replication factor C subunit 1, putative 0.0049 0.0028 0.4056
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0333 0.169
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0537 0.0598 0.305
Trypanosoma brucei heat shock protein, putative 0.0071 0.0053 0.1461
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0027 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0645 0.0723 0.2901
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Schistosoma mansoni biogenic amine (5HT) receptor 0.0037 0.0014 0.005
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0031 0.0007 0.0025
Brugia malayi follicle stimulating hormone receptor 0.0037 0.0014 0.0072
Plasmodium falciparum ataxin-2 like protein, putative 0.0081 0.0065 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0152 0.0148 0.0146
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0019 0.0085
Schistosoma mansoni zinc finger protein 0.0065 0.0046 0.0179
Brugia malayi conserved hypotetical protein 0.0056 0.0037 0.0187
Brugia malayi Nuclear hormone receptor-like 1 0.012 0.011 0.0563
Schistosoma mansoni kinase 0.0057 0.0038 0.0145
Onchocerca volvulus 0.0037 0.0014 0.0163
Plasmodium vivax ataxin-2 like protein, putative 0.0081 0.0065 0.3005
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.012 0.011 0.0563
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0048 0.0027 0.0138
Onchocerca volvulus 0.0037 0.0014 0.0163
Schistosoma mansoni hypothetical protein 0.0036 0.0013 0.0046
Echinococcus granulosus histone acetyltransferase KAT2B 0.0054 0.0033 0.0045
Brugia malayi beta-lactamase 0.0205 0.021 0.107
Brugia malayi Nuclear hormone receptor family member nhr-40 0.012 0.011 0.0563
Schistosoma mansoni tar DNA-binding protein 0.0598 0.0669 0.2681
Echinococcus granulosus somatostatin receptor 0.0037 0.0014 0.0018
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.012 0.011 0.1276
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0141 0.0136 0.0693
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0019 0.0027
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0032 0.003
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0258 0.0272 0.027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.012 0.011 0.0563
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.1698 0.1951 0.2793
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0014 0.0018
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0636 0.0713 0.3637
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0144
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0158 0.0155 0.0618
Echinococcus granulosus SAM and MBT domain containing protein 0.0104 0.0092 0.013
Trypanosoma brucei heat shock protein 90, putative 0.0071 0.0053 0.1461
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0037 0.0014 0.0012
Loa Loa (eye worm) heat shock protein 75 0.0029 0.0005 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0016 0.0069
Echinococcus granulosus g protein coupled receptor 0.0037 0.0014 0.0018
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0258 0.0272 0.1086
Schistosoma mansoni ap endonuclease 0.006 0.0041 0.0158
Brugia malayi serine/threonine-protein kinase plk-2 0.0113 0.0103 0.0524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0047 0.0229
Echinococcus multilocularis sex peptide receptor 0.0037 0.0014 0.0012
Trichomonas vaginalis heat shock protein, putative 0.0056 0.0036 0.0174
Echinococcus multilocularis heat shock protein 90 0.0056 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus granulosus neuropeptides capa receptor 0.0037 0.0014 0.0018
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0103 0.0513
Brugia malayi Pre-SET motif family protein 0.0099 0.0086 0.044
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0152 0.0148 0.0212
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0205 0.021 0.0836
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0287 0.1455
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0027 0.0003 0.0001
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0113 0.0103 0.2878
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0263 0.0277 0.0394
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0119 0.0109 0.0154
Plasmodium falciparum citrate synthase, mitochondrial, putative 0.0046 0.0024 0.3445
Echinococcus granulosus tm gpcr rhodopsin 0.0037 0.0014 0.0018
Onchocerca volvulus 0.0766 0.0865 1
Trypanosoma cruzi Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0061 0.0042 0.1139
Echinococcus multilocularis neuropeptide receptor 0.0037 0.0014 0.0012
Plasmodium vivax unspecified product 0.0046 0.0024 0.1035
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0037 0.0014 0.0072
Onchocerca volvulus 0.0111 0.01 0.1159
Echinococcus granulosus ecdysone induced protein 78C 0.012 0.011 0.0155
Echinococcus multilocularis g protein coupled receptor 0.0037 0.0014 0.0012
Schistosoma mansoni hypothetical protein 0.0037 0.0014 0.005
Schistosoma mansoni histamine h1 receptor 0.0037 0.0014 0.005
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.019 0.0192 0.0273
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Leishmania major 60S ribosomal protein L19, putative 0.0031 0.0007 0.0203
Trichomonas vaginalis heat shock protein, putative 0.0071 0.0053 0.026
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0041 0.0019 0.0017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Echinococcus granulosus tumor protein p63 0.037 0.0403 0.0574
Entamoeba histolytica hypothetical protein 0.0035 0.0011 0.0221
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0033 0.0156
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0017 0.0077
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0099 0.0086 0.034
Plasmodium vivax heat shock protein, putative 0.0029 0.0005 0.0076
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0017 0.0336
Echinococcus granulosus snurportin 1 0.07 0.0788 0.1125
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0023 0.0261
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.0019 0.0027
Echinococcus multilocularis protein dispatched 1 0.0161 0.0159 0.0157
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.012 0.011 0.0437
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.0176 0.0176 0.0896
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0017 0.0077
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0014 0.0012
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0029 0.0005 0.0053
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Entamoeba histolytica heat shock protein 90, putative 0.0071 0.0053 0.1024
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0065 0.0047 0.024
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0063 0.0045 0.0172
Schistosoma mansoni neuropeptide receptor 0.0037 0.0014 0.005
Echinococcus granulosus importin subunit beta 1 0.0066 0.0047 0.0065
Echinococcus granulosus heat shock protein 90 0.0056 0.0036 0.005
Mycobacterium ulcerans heat shock protein 90 0.0056 0.0036 0.0052
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0037 0.0014 0.0012
Schistosoma mansoni amine GPCR 0.0037 0.0014 0.005
Onchocerca volvulus 0.0037 0.0014 0.0163
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0014 0.0366
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0037 0.0014 0.0012
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Schistosoma mansoni nuclear receptor 0.0056 0.0037 0.014
Onchocerca volvulus 0.0037 0.0014 0.0163
Brugia malayi nuclear hormone receptor 0.012 0.011 0.0563
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0019 0.0085
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.0064 1
Loa Loa (eye worm) hypothetical protein 0.012 0.011 0.0563
Echinococcus multilocularis muscleblind protein 0.0145 0.0139 0.0138
Loa Loa (eye worm) nuclear receptor NHR-67 0.0056 0.0037 0.0187
Echinococcus multilocularis sterol regulatory element binding protein 0.0141 0.0136 0.0134
Schistosoma mansoni tar DNA-binding protein 0.0598 0.0669 0.2681
Echinococcus granulosus dro:myosuppressin receptor 0.0037 0.0014 0.0018
Trypanosoma cruzi polo-like protein kinase, putative 0.0113 0.0103 0.284
Echinococcus granulosus tar DNA binding protein 0.0598 0.0669 0.0955
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Plasmodium vivax heat shock protein 86, putative 0.0071 0.0053 0.2427
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0014 0.0061
Entamoeba histolytica hypothetical protein 0.0049 0.0028 0.0543
Echinococcus granulosus muscleblind protein 0.0145 0.0139 0.0197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0033 0.0156
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0271 0.0287 0.1465
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0041 0.0019 0.0097
Trypanosoma cruzi ISWI complex protein 0.0065 0.0046 0.1246
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0036 0.0173
Echinococcus multilocularis zinc finger protein 0.0093 0.008 0.0078
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0027 0.0003 0.0014
Brugia malayi MH1 domain containing protein 0.0027 0.0002 0.0009
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0025 0.0654
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Loa Loa (eye worm) transcription factor SMAD2 0.0389 0.0425 0.2167
Brugia malayi Niemann-Pick C1 protein precursor 0.033 0.0355 0.1813
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Echinococcus multilocularis Niemann Pick C1 protein 0.033 0.0355 0.0354
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0037 0.0014 0.005
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0037 0.0014 0.005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0014
Mycobacterium leprae Probable lipase LipE 0.0205 0.021 0.1074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.001 0.0039
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0287 0.0305 0.0434
Loa Loa (eye worm) hypothetical protein 0.0141 0.0136 0.0693
Entamoeba histolytica hypothetical protein 0.0053 0.0033 0.0634
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0103 0.0513
Loa Loa (eye worm) hypothetical protein 0.0066 0.0047 0.0242
Schistosoma mansoni growth hormone secretagogue receptor 0.0037 0.0014 0.005
Entamoeba histolytica serine/threonine protein kinase, putative 0.0113 0.0103 0.198
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0027 0.0003 0.0004
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Brugia malayi latrophilin 2 splice variant baaae 0.0367 0.0399 0.2038
Brugia malayi RE15519p 0.0037 0.0014 0.0072
Echinococcus granulosus nuclear receptor 2DBD gamma 0.012 0.011 0.0155
Loa Loa (eye worm) hypothetical protein 0.0205 0.021 0.107
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Echinococcus granulosus dna polymerase eta 0.0096 0.0082 0.0116
Schistosoma mansoni retinoid-x-receptor (RXR) 0.012 0.011 0.0437
Brugia malayi Nuclear hormone receptor family member nhr-1 0.012 0.011 0.0563
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0061 0.0042 0.1157
Loa Loa (eye worm) hypothetical protein 0.012 0.011 0.0563
Brugia malayi nuclear hormone receptor 0.0056 0.0037 0.0187
Schistosoma mansoni biogenic amine receptor 0.0037 0.0014 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.003 0.0142
Loa Loa (eye worm) latrophilin receptor protein 2 0.017 0.0169 0.0863
Echinococcus granulosus replication factor c subunit 1 0.0049 0.0028 0.0038
Loa Loa (eye worm) hypothetical protein 0.0171 0.017 0.0868
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0017 0.0077
Echinococcus granulosus polycomb protein SCMH1 0.0104 0.0092 0.013
Brugia malayi Dopamine receptor 0.0037 0.0014 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-19 0.012 0.011 0.0563
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0021 0.0098
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0014 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.001 0.0039
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0056 0.0037 0.0423
Entamoeba histolytica hypothetical protein 0.019 0.0192 0.3711
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0056 0.0036 0.1019
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0287 0.1455
Brugia malayi Inositol-1 0.0037 0.0014 0.0072
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0048 0.0027 0.0421
Echinococcus granulosus 7tm_1 domain containing protein 0.0037 0.0014 0.0018
Trypanosoma cruzi DNA polymerase eta, putative 0.0096 0.0082 0.2269
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0205 0.021 0.107
Brugia malayi Nuclear hormone receptor family member nhr-49 0.012 0.011 0.0563
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0028 0.0132
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Schistosoma mansoni 60S ribosomal protein L19 0.0031 0.0007 0.0022
Echinococcus multilocularis allatostatin A receptor 0.0037 0.0014 0.0012
Schistosoma mansoni hypothetical protein 0.0287 0.0305 0.122
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0311 0.0333 0.6422
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0099 0.0086 0.0084
Brugia malayi neuropeptide F receptor 0.0037 0.0014 0.0072
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0205 0.021 0.03
Brugia malayi Nuclear hormone receptor-like 1 0.0063 0.0045 0.0227
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.012 0.011 0.0155
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0041 0.0019 0.0069
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0037 0.0014 0.0012
Brugia malayi Importin beta-1 subunit 0.0066 0.0047 0.0242
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0014 0.006
Entamoeba histolytica 60S ribosomal protein L19, putative 0.0031 0.0007 0.014
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.008 0.0064 0.9855
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0014 0.0018
Schistosoma mansoni DNA polymerase eta 0.0096 0.0082 0.0325
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0119 0.0109 0.0557
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus multilocularis lysosomal alpha glucosidase 0.0167 0.0165 0.0164
Schistosoma mansoni inositol monophosphatase 0.0037 0.0014 0.005
Echinococcus multilocularis dnaJ subfamily B 0.0875 0.0991 0.099
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0019 0.0027
Echinococcus granulosus neuropeptide Y receptor 0.0037 0.0014 0.0018
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Echinococcus granulosus histone acetyltransferase MYST2 0.0119 0.0109 0.0154
Giardia lamblia Heat shock protein HSP 90-alpha 0.0056 0.0036 0.0894
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0056 0.0037 0.0035
Echinococcus multilocularis GPCR, family 2 0.017 0.0169 0.0167
Schistosoma mansoni amine GPCR 0.0037 0.0014 0.005
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0014 0.0018
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0167 0.0165 0.0844
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0005 0.0013
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0041 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0636 0.0713 0.2858
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0041 0.0655
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.019 0.0957
Loa Loa (eye worm) beta-lactamase 0.0205 0.021 0.107
Toxoplasma gondii heat shock protein HSP90 0.0071 0.0053 0.0875
Plasmodium falciparum endoplasmin, putative 0.0043 0.0021 0.2951
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0037 0.0014 0.0018
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0103 0.0513
Echinococcus granulosus microtubule associated protein 2 0.2159 0.2489 0.3561
Schistosoma mansoni hypothetical protein 0.017 0.0169 0.0673
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Onchocerca volvulus 0.0123 0.0114 0.132
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0056 0.0037 0.014
Loa Loa (eye worm) inositol-1 0.0037 0.0014 0.0072
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0034 0.001 0.0248
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0258 0.0272 0.7603
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0027 0.0003 0.0002
Toxoplasma gondii citrate synthase I 0.0046 0.0024 0.0373
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0019 0.048
Brugia malayi Tnks protein 0.0035 0.0011 0.0058
Loa Loa (eye worm) hypothetical protein 0.0205 0.021 0.107
Schistosoma mansoni opsin-like receptor 0.0037 0.0014 0.005
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Onchocerca volvulus 0.0104 0.0092 0.1067
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0157 0.0154 0.4272
Schistosoma mansoni RAR-like nuclear receptor 0.012 0.011 0.0437
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0034 0.001 0.0227
Loa Loa (eye worm) G-protein coupled receptor 0.0037 0.0014 0.0072
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0037 0.0014 0.0072
Trypanosoma brucei unspecified product 0.0028 0.0004 0.008
Leishmania major DNA polymerase eta, putative 0.0067 0.0049 0.1381
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0205 0.021 0.0836
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0258 0.0272 0.7603
Echinococcus multilocularis replication factor c subunit 1 0.0049 0.0028 0.0026
Trichomonas vaginalis D-aminoacylase, putative 0.0205 0.021 0.1059
Loa Loa (eye worm) hypothetical protein 0.0041 0.0019 0.0096
Brugia malayi mbt repeat family protein 0.0104 0.0092 0.0471
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.008 0.0064 0.1854
Brugia malayi mbt repeat family protein 0.0104 0.0092 0.0471
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0021 0.0098
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Schistosoma mansoni alpha glucosidase 0.0037 0.0014 0.0049
Brugia malayi Muscleblind-like protein 0.0145 0.0139 0.0712
Schistosoma mansoni retinoic acid receptor RXR 0.012 0.011 0.0437
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0049 0.0028 0.0543
Loa Loa (eye worm) hypothetical protein 0.0358 0.0388 0.1979
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0333 0.169
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0037 0.0014 0.0012
Onchocerca volvulus 0.0027 0.0003 0.0031
Loa Loa (eye worm) heterochromatin protein 1 0.0074 0.0057 0.0289
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.017 0.0169 0.0167
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Schistosoma mansoni GTP-binding protein alpha subunit 0.0027 0.0003 0.0004
Mycobacterium leprae conserved hypothetical protein 0.0205 0.021 0.1074
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0031 0.0007 0.0025
Echinococcus granulosus lysosomal alpha glucosidase 0.0167 0.0165 0.0234
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0598 0.0669 0.3412
Echinococcus multilocularis thymidine phosphorylase 0.6015 0.6988 0.6987
Loa Loa (eye worm) hypothetical protein 0.0205 0.021 0.107
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.6015 0.6988 1
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0103 0.0513
Loa Loa (eye worm) hypothetical protein 0.0063 0.0045 0.0227
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0056 0.0036 0.1001
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0056 0.0037 0.014
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0144
Loa Loa (eye worm) hypothetical protein 0.0104 0.0092 0.0471
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0027 0.0003 0.0014
Trypanosoma brucei unspecified product 0.0028 0.0004 0.008
Brugia malayi Nuclear hormone receptor-like 1 0.0063 0.0045 0.0227
Onchocerca volvulus 0.0027 0.0003 0.0031
Loa Loa (eye worm) CHromoDomain protein family member 0.0027 0.0002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0144
Trypanosoma cruzi hypothetical protein, conserved 0.0205 0.021 0.5852
Brugia malayi larval opioid receptor 0.0037 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.0063 0.0045 0.0227
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0178 0.09
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0036 0.0013 0.0016
Brugia malayi nuclear receptor RXR 0.0056 0.0037 0.0187
Echinococcus granulosus neuropeptide Y receptor 0.0037 0.0014 0.0018
Brugia malayi topoisomerase 0.0049 0.0028 0.0144
Echinococcus multilocularis fmrfamide receptor 0.0037 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Onchocerca volvulus Neuropeptide F receptor homolog 0.0037 0.0014 0.0163
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0037 0.0014 0.0012
Brugia malayi CHE-14 protein 0.0141 0.0136 0.0693
Echinococcus granulosus orexin receptor type 2 0.0037 0.0014 0.0018
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0032 0.0164
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0034 0.001 0.0248
Schistosoma mansoni alpha-glucosidase 0.0144 0.0138 0.0549
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0263 0.0277 0.0275
Loa Loa (eye worm) hypothetical protein 0.0096 0.0082 0.0421
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.012 0.011 0.0563
Brugia malayi beta-lactamase family protein 0.0205 0.021 0.107
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0072 0.0055 0.0053
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.008 0.0064 0.0329
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0205 0.021 0.03
Echinococcus multilocularis SAM and MBT domain containing protein 0.0104 0.0092 0.0091
Giardia lamblia Fructose-bisphosphate aldolase 0.0311 0.0333 1
Trypanosoma cruzi heat shock protein 90, putative 0.0042 0.0019 0.0493
Brugia malayi orphan nuclear receptor NR2E1 0.0056 0.0037 0.0187
Loa Loa (eye worm) hypothetical protein 0.0155 0.0151 0.0771
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0037 0.0014 0.0072
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0041 0.0058
Echinococcus granulosus cpg binding protein 0.0138 0.0132 0.0186
Echinococcus multilocularis serine protein kinase ATM 0.0033 0.0009 0.0008
Echinococcus multilocularis serotonin receptor 0.0037 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Schistosoma mansoni biogenic amine (5HT) receptor 0.0037 0.0014 0.005
Brugia malayi F/Y-rich N-terminus family protein 0.0049 0.0028 0.0144
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0178 0.09
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0056 0.0037 0.0035
Entamoeba histolytica G protein alpha subunit, putative 0.0027 0.0003 0.0052
Echinococcus granulosus g protein coupled receptor 0.0037 0.0014 0.0018
Trypanosoma brucei DNA repair protein, putative 0.0061 0.0042 0.1157
Trypanosoma brucei unspecified product 0.0041 0.0019 0.05
Brugia malayi Bromodomain containing protein 0.0327 0.0353 0.1799
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0037 0.0014 0.0018
Loa Loa (eye worm) hypothetical protein 0.033 0.0355 0.1813
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0099 0.0086 0.1452
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0019 0.048
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0333 0.169
Plasmodium vivax unspecified product 0.0046 0.0024 0.1035
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0032 0.0046
Schistosoma mansoni endoplasmin 0.0071 0.0053 0.0207
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Echinococcus granulosus sterol regulatory element binding protein 0.0141 0.0136 0.0192
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0093 0.0079 0.0111
Echinococcus multilocularis nuclear receptor nhr 48 0.0056 0.0037 0.0035
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0067 0.0049 0.0808
Brugia malayi hypothetical protein 0.0063 0.0045 0.0227
Toxoplasma gondii histone lysine methyltransferase SET1 0.025 0.0262 0.4526
Brugia malayi Nuclear hormone receptor family member nhr-31 0.012 0.011 0.0563
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0017 0.0077
Echinococcus multilocularis dna polymerase eta 0.0096 0.0082 0.0081
Brugia malayi TAR-binding protein 0.0598 0.0669 0.3412
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0014 0.0195
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0014 0.0012
Brugia malayi hypothetical protein 0.0063 0.0045 0.0227
Echinococcus granulosus heat shock protein 0.0071 0.0053 0.0074
Schistosoma mansoni hypothetical protein 0.0087 0.0072 0.0284
Trypanosoma brucei heat shock protein, putative 0.0071 0.0053 0.1461
Schistosoma mansoni poly [ADP-ribose] polymerase 0.047 0.0519 0.2078
Schistosoma mansoni hypothetical protein 0.1447 0.1659 0.6663
Brugia malayi RNA, U transporter 1 0.0187 0.0188 0.0962
Schistosoma mansoni zinc finger protein 0.0093 0.008 0.0313
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0019 0.05
Echinococcus granulosus thyroid hormone receptor alpha 0.0056 0.0037 0.005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0056 0.0037 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0036 0.0171
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0333 0.169
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0049 0.0028 0.0132
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0009 0.0048
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0014 0.0071
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0014 0.0012
Brugia malayi MH2 domain containing protein 0.0027 0.0002 0.0009
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.0064 0.0092
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0636 0.0713 0.0711
Trypanosoma brucei heat shock protein 84, putative 0.0029 0.0005 0.0095
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0027 0.0003 0.0004
Trypanosoma brucei ISWI complex protein 0.0065 0.0046 0.1264
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0021 0.0096

Activities

Activity type Activity value Assay description Source Reference
Change (functional) = -4.4 % Mean change in heart rate recorded 14 min after the administration of compound. ChEMBL. 3005568
EC25 (functional) = 16.1 ug ml-1 Concentration required to reduce maximum following frequencu (MFF) of isolated guinea pig atria by 25% ChEMBL. 3005568
ED50 (functional) 0 mg kg-1 ED 50 value against aconitine-induced arrhythmias in mice; IA is Inactive ChEMBL. 3005568
ED50 (functional) < 1 mg kg-1 Effective dose of the compound that antagonized arrhythmias evoked by coronary artery ligation in the rat was measured at 2.0 mg/kg dose ChEMBL. 3005568
Heart rate (functional) = 387 beats min-1 Effect of the compound on heart rate after isoprenaline induced tachycardia in the anesthetized rat at 1 mg/kg dose ChEMBL. 3005568
Heart rate (functional) = 393 beats min-1 Effect of the compound on heart rate on 1 min post isoprenaline induced tachycardia in the anesthetized rat at 1.0 mg/kg dose. ChEMBL. 3005568
Heart rate (functional) = 405 beats min-1 Effect of the compound on heart rate before isoprenaline induced tachycardia in the anesthetized rat at 1 mg/kg dose ChEMBL. 3005568
Increase (functional) = 1.6 % Maximum increase in heart rate evoked by isoprenaline. ChEMBL. 3005568
VF (functional) = 14 % Antagonism of Ventricular Fibrilloflutter (VF) evoked by coronary artery ligation in the rat measured at 2 mg/kg dose ChEMBL. 3005568
VF (functional) = 29 % Compound was tested for antagonism of Ventricular Fibrilloflutter (VF) evoked by coronary artery ligation in the rat measured at 1 mg/kg dose ChEMBL. 3005568

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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