Detailed information for compound 135506

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 414.624 | Formula: C26H42N2O2
  • H donors: 3 H acceptors: 1 LogP: 4.42 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNC1CCC2C1(C)CCC1C2CCc2c1ccc(c2)OCC(CNC(C)(C)C)O
  • InChi: 1S/C26H42N2O2/c1-25(2,3)28-15-18(29)16-30-19-7-9-20-17(14-19)6-8-22-21(20)12-13-26(4)23(22)10-11-24(26)27-5/h7,9,14,18,21-24,27-29H,6,8,10-13,15-16H2,1-5H3
  • InChiKey: DLVAQEYQVGVGRK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0152 0.0148 0.0212
Brugia malayi Steroid receptor seven-up type 2 0.012 0.011 0.0563
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0028 0.0132
Echinococcus granulosus nuclear receptor nhr 48 0.0056 0.0037 0.005
Brugia malayi Tachykinin-like peptides receptor 99D 0.0037 0.0014 0.0072
Entamoeba histolytica heat shock protein 90, putative 0.0071 0.0053 0.1024
Schistosoma mansoni topbp1 0.0049 0.0028 0.0106
Brugia malayi steroid hormone receptor 0.012 0.011 0.0563
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0027 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trypanosoma brucei hypothetical protein, conserved 0.0205 0.021 0.586
Schistosoma mansoni hypothetical protein 0.0037 0.0014 0.005
Brugia malayi G protein-coupled receptor 0.0037 0.0014 0.0072
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.006 0.0041 0.104
Loa Loa (eye worm) hypothetical protein 0.012 0.011 0.0563
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0031 0.0007 0.0151
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0056 0.0037 0.0035
Brugia malayi MH1 domain containing protein 0.0027 0.0002 0.0009
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0027 0.0002 0.0001
Schistosoma mansoni cpg binding protein 0.0123 0.0114 0.0452
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.012 0.011 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.006 0.0041 0.0059
Echinococcus granulosus GPCR family 2 0.017 0.0169 0.024
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0019 0.0027
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0331 0.0357 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0014 0.0012
Mycobacterium ulcerans hypothetical protein 0.0205 0.021 0.03
Brugia malayi hypothetical protein 0.0049 0.0028 0.0144
Brugia malayi WGR domain containing protein 0.0258 0.0272 0.1387
Echinococcus granulosus dna polymerase kappa 0.0041 0.0019 0.0025
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0034 0.001 0.0279
Schistosoma mansoni nuclear receptor 0.0056 0.0037 0.014
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0004 0.008
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.017 0.0169 0.024
Echinococcus granulosus Niemann Pick C1 protein 0.0471 0.052 0.0742
Echinococcus granulosus zinc finger protein 0.0093 0.008 0.0111
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0049 0.0028 0.0759
Leishmania major importin beta-1 subunit, putative 0.0053 0.0033 0.0921
Echinococcus granulosus alpha 1A adrenergic receptor 0.0037 0.0014 0.0018
Echinococcus granulosus tachykinin peptides receptor 99D 0.0037 0.0014 0.0018
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0019 0.0218
Echinococcus granulosus expressed protein 0.0027 0.0003 0.0001
Loa Loa (eye worm) Smad1 0.0027 0.0002 0.0009
Echinococcus multilocularis g protein coupled receptor 0.0037 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus granulosus ribosomal protein L19 0.0031 0.0007 0.0008
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0027 0.0003 0.0014
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0113 0.0103 0.0145
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Plasmodium vivax importin-beta 2, putative 0.0066 0.0047 0.2146
Echinococcus granulosus heat shock protein 90 0.0071 0.0053 0.0074
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0063 0.0045 0.0172
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Trichomonas vaginalis conserved hypothetical protein 0.0141 0.0136 0.0682
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0014 0.034
Brugia malayi Serotonin receptor 0.0037 0.0014 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Schistosoma mansoni bromodomain containing protein 0.0029 0.0004 0.001
Echinococcus granulosus beta LACTamase domain containing family member 0.0205 0.021 0.0298
Schistosoma mansoni hypothetical protein 0.0136 0.013 0.0515
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Echinococcus granulosus biogenic amine 5HT receptor 0.0037 0.0014 0.0018
Mycobacterium tuberculosis Probable lipase LipE 0.0205 0.021 0.03
Brugia malayi ecdysone receptor 0.0056 0.0037 0.0187
Loa Loa (eye worm) hypothetical protein 0.0145 0.0139 0.0712
Echinococcus multilocularis cpg binding protein 0.0138 0.0132 0.013
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0049 0.0028 0.0132
Schistosoma mansoni chromobox protein 0.0074 0.0057 0.0221
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0037 0.0014 0.0012
Echinococcus granulosus citrate synthase 0.0046 0.0024 0.0032
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0014 0.0192
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0037 0.0014 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0036 0.0171
Entamoeba histolytica hypothetical protein 0.019 0.0192 0.3711
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0014 0.0061
Schistosoma mansoni DNA ligase IV 0.0049 0.0028 0.0106
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0033 0.0009 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0028 0.0132
Schistosoma mansoni hypothetical protein 0.0136 0.013 0.0515
Loa Loa (eye worm) glutaminase 2 0.1705 0.196 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0264 0.0279 0.1115
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.001 0.0049
Schistosoma mansoni biogenic amine receptor 0.0037 0.0014 0.005
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0014 0.0269
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0014 0.0061
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0027 0.0003 0.0001
Trypanosoma brucei PAB1-binding protein , putative 0.0081 0.0065 0.1797
Schistosoma mansoni thyroid hormone receptor 0.0406 0.0445 0.1781
Brugia malayi hypothetical protein 0.0027 0.0003 0.0014
Echinococcus multilocularis neuropeptides capa receptor 0.0037 0.0014 0.0012
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.001 0.0014
Schistosoma mansoni chromobox protein 0.0074 0.0057 0.0221
Brugia malayi Nuclear hormone receptor family member nhr-25 0.012 0.011 0.0563
Brugia malayi hypothetical protein 0.0056 0.0037 0.0187
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0636 0.0713 0.2858
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0036 0.0171
Echinococcus multilocularis neuropeptide receptor A26 0.0037 0.0014 0.0012
Brugia malayi 60S ribosomal protein L19 0.0031 0.0007 0.0037
Onchocerca volvulus 0.0056 0.0037 0.0423
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0027 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trichomonas vaginalis helicase, putative 0.0028 0.0003 0.0005
Schistosoma mansoni hypothetical protein 0.0367 0.0399 0.1599
Echinococcus multilocularis importin subunit beta 1 0.0066 0.0047 0.0046
Loa Loa (eye worm) hypothetical protein 0.0029 0.0004 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0016 0.0069
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0027 0.0003 0.0001
Schistosoma mansoni steroid hormone receptor ad4bp 0.012 0.011 0.0437
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0065 0.0047 0.1291
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0019 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0019 0.0085
Loa Loa (eye worm) bromodomain containing protein 0.0078 0.0062 0.0317
Echinococcus granulosus hypothetical protein 0.0037 0.0014 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0005 0.0013
Brugia malayi MH2 domain containing protein 0.0027 0.0002 0.0009
Echinococcus granulosus neuropeptide FF receptor 2 0.0037 0.0014 0.0018
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0041 0.0156
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0014 0.0012
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0422 0.0464 0.0462
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0065 0.0047 0.0045
Brugia malayi RNA binding protein 0.0598 0.0669 0.3412
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0205 0.021 0.03
Schistosoma mansoni heat shock protein 0.0071 0.0053 0.0207
Echinococcus granulosus ribosomal protein L19 0.0031 0.0007 0.0008
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0037 0.0014 0.0072
Plasmodium vivax SET domain protein, putative 0.0099 0.0086 0.4027
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Plasmodium vivax hypothetical protein, conserved 0.0205 0.021 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0037 0.0014 0.005
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0037 0.0014 0.005
Echinococcus multilocularis histone acetyltransferase MYST2 0.0119 0.0109 0.0107
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0103 0.0513
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0037 0.0014 0.0012
Echinococcus granulosus 7TM GPCR rhodopsin 0.0037 0.0014 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0021 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0021 0.0098
Loa Loa (eye worm) hypothetical protein 0.0054 0.0034 0.0174
Loa Loa (eye worm) nuclear hormone receptor 0.0056 0.0037 0.0187
Onchocerca volvulus 0.0037 0.0014 0.0163
Echinococcus multilocularis expressed conserved protein 0.031 0.0332 0.033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0017 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0024 0.0112
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0037 0.0014 0.0018
Loa Loa (eye worm) hypothetical protein 0.0205 0.021 0.107
Echinococcus multilocularis citrate synthase 0.0046 0.0024 0.0023
Trypanosoma cruzi heat shock protein 85, putative 0.0071 0.0053 0.1443
Loa Loa (eye worm) phosphatidylinositol 3 0.0065 0.0047 0.024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0016 0.0069
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.008 0.0064 0.0089
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0333 0.169
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Brugia malayi RNA recognition motif domain containing protein 0.0598 0.0669 0.3412
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0139 0.0196
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus granulosus g protein coupled receptor 0.0037 0.0014 0.0018
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.012 0.011 0.0437
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0049 0.0028 0.0144
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Mycobacterium ulcerans lipase LipD 0.0205 0.021 0.03
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0034 0.0011 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0014 0.0012
Entamoeba histolytica Ran family GTPase 0.0048 0.0027 0.0523
Loa Loa (eye worm) MH1 domain-containing protein 0.0027 0.0002 0.0009
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0049 0.0028 0.0144
Loa Loa (eye worm) G-protein coupled receptor 0.0037 0.0014 0.0072
Echinococcus multilocularis polycomb protein SCMH1 0.0104 0.0092 0.0091
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0041 0.0058
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0027 0.0003 0.0004
Trichomonas vaginalis endoplasmin, putative 0.0043 0.0021 0.0097
Trypanosoma brucei heat shock protein, putative 0.0071 0.0053 0.1461
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0205 0.021 0.03
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0027 0.0003 0.0014
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Brugia malayi Heterochromatin protein 1 0.0074 0.0057 0.0289
Loa Loa (eye worm) hypothetical protein 0.0299 0.0319 0.1628
Echinococcus multilocularis serotonin receptor 0.0037 0.0014 0.0012
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0287 0.0305 0.0303
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0036 0.0013 0.0011
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0271 0.0287 0.1465
Treponema pallidum heat shock protein 90 0.0056 0.0036 0.1011
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.006 0.0041 0.1105
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Brugia malayi chromobox protein homolog 3 0.0041 0.0019 0.0096
Echinococcus granulosus neuropeptide receptor A26 0.0037 0.0014 0.0018
Schistosoma mansoni hypothetical protein 0.019 0.0192 0.0767
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0171 0.017 0.0168
Echinococcus multilocularis tankyrase 0.0035 0.0011 0.001
Brugia malayi nuclear receptor NHR-88 0.0056 0.0037 0.0187
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0017 0.0313
Trypanosoma brucei glucosidase, putative 0.0037 0.0014 0.036
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus granulosus geminin 0.1447 0.1659 0.2372
Loa Loa (eye worm) hypothetical protein 0.012 0.011 0.0563
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0034 0.0011 0.0009
Brugia malayi nuclear hormone receptor family member odr-7 0.0056 0.0037 0.0187
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Onchocerca volvulus 0.0049 0.0028 0.0326
Schistosoma mansoni sex comb on midleg homolog 0.0104 0.0092 0.0364
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.008 0.0064 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0014
Loa Loa (eye worm) neuropeptide F receptor 0.0037 0.0014 0.0072
Giardia lamblia Kinase, PLK 0.0113 0.0103 0.2929
Brugia malayi Serotonin receptor 0.0037 0.0014 0.0072
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0048 0.0027 0.0138
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0027 0.0003 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.012 0.011 0.0563
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0037 0.0014 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0102 0.009 0.0088
Schistosoma mansoni myelin transcription factor 1 myt1 0.0119 0.0109 0.0432
Mycobacterium tuberculosis Conserved protein 0.0205 0.021 0.03
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0019 0.0097
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0037 0.0014 0.005
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.047 0.0519 0.0517
Loa Loa (eye worm) hypothetical protein 0.0119 0.0109 0.0557
Loa Loa (eye worm) hypothetical protein 0.0205 0.021 0.107
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0014 0.006
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0065 0.0047 0.1291
Brugia malayi hypothetical protein 0.0052 0.0032 0.0162
Loa Loa (eye worm) TYRA-2 protein 0.0037 0.0014 0.0072
Trypanosoma cruzi importin beta-1 subunit, putative 0.0053 0.0033 0.0872
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0102 0.009 0.0355
Leishmania major citrate synthase, putative 0.0046 0.0024 0.0683
Schistosoma mansoni topbp1 0.0049 0.0028 0.0106
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0037 0.0014 0.005
Trypanosoma brucei poly(adp-ribose) polymerase 0.0258 0.0272 0.7608
Loa Loa (eye worm) hypothetical protein 0.012 0.011 0.0563
Brugia malayi CXXC zinc finger family protein 0.0123 0.0114 0.0582
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0014 0.0397
Entamoeba histolytica 60S ribosomal protein L19, putative 0.0031 0.0007 0.014
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.1698 0.1951 1
Echinococcus granulosus Niemann Pick C1 protein 0.033 0.0355 0.0506
Mycobacterium tuberculosis Conserved protein 0.0205 0.021 0.03
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0065 0.0047 0.132
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0158 0.0155 0.0154
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0063 0.0045 0.0061
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0034 0.001 0.0033
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0104 0.0092 0.1067
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0037 0.0014 0.005
Schistosoma mansoni neuropeptide f receptor 76f 0.0037 0.0014 0.005
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.012 0.011 0.0563
Brugia malayi hypothetical protein 0.019 0.0192 0.0982
Brugia malayi Glycosyl hydrolases family 31 protein 0.0167 0.0165 0.0844
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0037 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0333 0.169
Echinococcus granulosus chromobox protein 1 0.0074 0.0057 0.0079
Schistosoma mansoni neuropeptide F-like receptor 0.0037 0.0014 0.005
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0049 0.0028 0.004
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0037 0.0014 0.0072
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0014 0.0018
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0027 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Onchocerca volvulus 0.0037 0.0014 0.0163
Schistosoma mansoni chromosome transmission fidelity factor 0.0049 0.0028 0.0106
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0054 0.0033 0.1468
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.008 0.0064 0.0328
Echinococcus multilocularis thyroid hormone receptor alpha 0.0406 0.0445 0.0443
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0027 0.0003 0.0014
Trypanosoma cruzi citrate synthase, putative 0.0046 0.0024 0.0633
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.012 0.011 0.0563
Echinococcus multilocularis Niemann Pick C1 protein 0.0471 0.052 0.0519
Brugia malayi Dopamine receptor protein 1 0.0037 0.0014 0.0072
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0014 0.006
Echinococcus granulosus sex peptide receptor 0.0037 0.0014 0.0018
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Onchocerca volvulus 0.0037 0.0014 0.0163
Echinococcus multilocularis g protein coupled receptor 0.0037 0.0014 0.0012
Mycobacterium tuberculosis Conserved protein 0.0205 0.021 0.03
Brugia malayi Bromodomain containing protein 0.0165 0.0164 0.0835
Echinococcus multilocularis heat shock protein 0.0071 0.0053 0.0051
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0185 0.0187 0.0953
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0031 0.0007 0.0151
Schistosoma mansoni hypothetical protein 0.07 0.0788 0.316
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0048 0.0027 0.3889
Echinococcus multilocularis neuropeptide Y receptor 0.0037 0.0014 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0287 0.1455
Echinococcus multilocularis ribosomal protein L19 0.0031 0.0007 0.0006
Plasmodium falciparum heat shock protein 90 0.0071 0.0053 0.8075
Trypanosoma cruzi PAB1-binding protein , putative 0.0081 0.0065 0.178
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0048 0.0027 0.0711
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.006 0.0041 0.5391
Toxoplasma gondii LsmAD domain-containing protein 0.0081 0.0065 0.1084
Mycobacterium ulcerans thymidine phosphorylase 0.6015 0.6988 1
Onchocerca volvulus 0.0027 0.0003 0.0031
Schistosoma mansoni amine GPCR 0.0037 0.0014 0.005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0014 0.0012
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.012 0.011 0.0155
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.033 0.0355 0.6851
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0047 0.0229
Echinococcus granulosus poly ADP ribose polymerase 1 0.047 0.0519 0.074
Onchocerca volvulus Tankyrase homolog 0.0035 0.0011 0.0132
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0027 0.0003 0.0002
Plasmodium vivax heat shock protein 90, putative 0.0029 0.0005 0.0076
Schistosoma mansoni amine GPCR 0.0037 0.0014 0.005
Brugia malayi hypothetical protein 0.0155 0.0151 0.0771
Onchocerca volvulus 0.012 0.011 0.1276
Toxoplasma gondii HEAT repeat-containing protein 0.0066 0.0047 0.0774
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0014 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.008 0.0064 0.2961
Echinococcus granulosus serine protein kinase ATM 0.0033 0.0009 0.0011
Echinococcus granulosus poly (ADP ribose) polymerase 0.0146 0.0141 0.0199
Schistosoma mansoni hypothetical protein 0.017 0.0169 0.0673
Brugia malayi CHD4 protein 0.0027 0.0002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0173 0.0173 0.0883
Echinococcus granulosus mixed lineage leukemia protein mll 0.0034 0.0011 0.0013
Brugia malayi Probable ClpP-like protease 0.008 0.0064 0.0328
Schistosoma mansoni neuropeptide receptor 0.0037 0.0014 0.005
Brugia malayi acetyltransferase, GNAT family protein 0.0158 0.0155 0.0793
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0037 0.0014 0.005
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0537 0.0598 0.305
Onchocerca volvulus 0.0037 0.0014 0.0163
Brugia malayi Pre-SET motif family protein 0.0674 0.0757 0.3861
Loa Loa (eye worm) hypothetical protein 0.0031 0.0007 0.0037
Echinococcus multilocularis neuropeptide Y receptor 0.0037 0.0014 0.0012
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.006 0.0041 0.0039
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.0064 0.1068
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0027 0.0003 0.0014
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0005 0.0012
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0014 0.0018
Schistosoma mansoni tar DNA-binding protein 0.0598 0.0669 0.2681
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0054 0.0033 0.0159
Entamoeba histolytica hypothetical protein 0.019 0.0192 0.3711
Entamoeba histolytica hypothetical protein 0.0033 0.0009 0.0182
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0017 0.0077
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.0064 1
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0178 0.09
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0014 0.006
Leishmania major mitochondrial DNA polymerase beta 0.0331 0.0357 1
Trichomonas vaginalis D-aminoacylase, putative 0.0205 0.021 0.1059
Loa Loa (eye worm) hypothetical protein 0.0162 0.016 0.0815
Loa Loa (eye worm) endoplasmin 0.0071 0.0053 0.0271
Brugia malayi DKFZp564C0469 protein 0.0049 0.0028 0.0144
Trypanosoma brucei heat shock protein, putative 0.0071 0.0053 0.1461
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0034 0.0011 0.0009
Echinococcus granulosus fetal alzheimer antigen falz 0.0102 0.009 0.0126
Loa Loa (eye worm) RNA binding protein 0.0598 0.0669 0.3412
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0636 0.0713 0.0711
Echinococcus multilocularis tumor protein p63 0.037 0.0403 0.0401
Giardia lamblia Replication factor C, subunit 1 0.0049 0.0028 0.0642
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0021 0.0098
Echinococcus granulosus WGR domain containing protein 0.0146 0.0141 0.0199
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.012 0.011 0.0155
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0056 0.0037 0.0035
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0029 0.0005 0.0004
Schistosoma mansoni nuclear receptor nhr-48 0.0056 0.0037 0.014
Echinococcus granulosus g-protein coupled receptor 0.0037 0.0014 0.0018
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0034 0.001 0.0227
Schistosoma mansoni heat shock protein 0.0029 0.0005 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0103 0.0513
Brugia malayi Calcitonin receptor-like protein seb-1 0.0537 0.0598 0.305
Entamoeba histolytica deoxycytidyl transferase, putative 0.0041 0.0019 0.0365
Schistosoma mansoni nuclear hormone receptor 0.0056 0.0037 0.014
Treponema pallidum DNA ligase (lig) 0.0049 0.0028 0.0763
Echinococcus multilocularis G protein coupled receptor 139 0.0037 0.0014 0.0012
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0037 0.0014 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-3 0.012 0.011 0.0563
Echinococcus multilocularis neuropeptide s receptor 0.0037 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0258 0.0272 0.1387
Loa Loa (eye worm) melatonin receptor type 1A 0.0037 0.0014 0.0072
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0042 0.0019 0.0018
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.006 0.0041 0.1105
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0056 0.0037 0.0423
Echinococcus multilocularis beta LACTamase domain containing family member 0.0205 0.021 0.0208
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0014 0.0018
Loa Loa (eye worm) G protein alpha subunit 3 0.0027 0.0003 0.0014
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0027 0.0003 0.0002
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0048 0.0027 0.061
Trypanosoma brucei 60S ribosomal protein L19, putative 0.0031 0.0007 0.0171
Trichomonas vaginalis esterase, putative 0.0205 0.021 0.1059
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.012 0.011 0.0437
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.012 0.011 0.0109
Onchocerca volvulus 0.0037 0.0014 0.0163
Loa Loa (eye worm) phosphatidylinositol 3 0.0034 0.001 0.0051
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0171 0.017 0.0677
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0021 0.0098
Entamoeba histolytica hypothetical protein 0.019 0.0192 0.3711
Loa Loa (eye worm) hypothetical protein 0.0063 0.0045 0.0227
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0157 0.0154 0.4283
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0056 0.0036 0.005
Mycobacterium tuberculosis Probable hydrolase 0.0205 0.021 0.03
Brugia malayi putative neuropeptide receptor 0.0037 0.0014 0.0072
Onchocerca volvulus 0.0037 0.0014 0.0163
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0027 0.0003 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0056 0.0037 0.0035
Brugia malayi beta-lactamase family protein 0.0205 0.021 0.107
Leishmania major GTP-binding protein, putative 0.0048 0.0027 0.076
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0027 0.0002 0.0001
Schistosoma mansoni transcription factor LCR-F1 0.019 0.0192 0.0767
Schistosoma mansoni hypothetical protein 0.017 0.0169 0.0673
Treponema pallidum exodeoxyribonuclease (exoA) 0.006 0.0041 0.1156
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0113 0.0103 0.0101
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0037 0.0014 0.005
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.006 0.0041 0.021
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0034 0.001 0.0008
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0014 0.006
Trypanosoma brucei 60S ribosomal protein L19, putative 0.0031 0.0007 0.0171
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0041 0.6143
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0287 0.1455
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0034 0.013
Loa Loa (eye worm) hypothetical protein 0.0032 0.0009 0.0043
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0014 0.0273
Schistosoma mansoni Tr4/Tr2 (homologue) 0.012 0.011 0.0437
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0014 0.0018
Trypanosoma brucei heat shock protein, putative 0.0071 0.0053 0.1461
Brugia malayi Nuclear hormone receptor E75 0.0056 0.0037 0.0187
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0025 0.0654
Echinococcus granulosus fmrfamide receptor 0.0037 0.0014 0.0018
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0152 0.0148 0.0757
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0021 0.0098
Loa Loa (eye worm) histone methyltransferase 0.0042 0.0019 0.0098
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.006 0.0041 0.1123
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0041 0.0199
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.0014 0.005
Onchocerca volvulus 0.0054 0.0034 0.0394
Schistosoma mansoni GTP-binding protein alpha subunit 0.0027 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0144
Schistosoma mansoni cpg binding protein 0.0138 0.0132 0.0523
Onchocerca volvulus 0.0096 0.0083 0.0963
Echinococcus multilocularis G-protein coupled receptor, putative 0.0037 0.0014 0.0012
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.008 0.0064 0.0062
Brugia malayi hypothetical protein 0.0081 0.0065 0.0332
Echinococcus multilocularis neuropeptides capa receptor 0.0037 0.0014 0.0012
Echinococcus multilocularis neuropeptide receptor 0.0037 0.0014 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-41 0.012 0.011 0.0563
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.012 0.011 0.0563
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trichomonas vaginalis penicillin-binding protein, putative 0.0205 0.021 0.1059
Giardia lamblia GTOR 0.0065 0.0047 0.1223
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0029 0.0005 0.0088
Brugia malayi Dopamine receptor protein 2 0.0037 0.0014 0.0072
Schistosoma mansoni importin beta-1 0.0066 0.0047 0.0183
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0014 0.006
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0014 0.006
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0023 0.0104
Echinococcus granulosus Protein patched homolog 1 0.0141 0.0136 0.0192
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0065 0.0047 0.0908
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0033 0.0156
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0048 0.0027 0.1169
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0037 0.0014 0.0018
Brugia malayi Pax transcription activation domain interacting protein 0.0049 0.0028 0.0144
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0333 0.169
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0056 0.0036 0.0186
Schistosoma mansoni zinc finger protein 0.0056 0.0037 0.014
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.001 0.0039
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0065 0.0047 0.0182
Loa Loa (eye worm) PHD-finger family protein 0.0087 0.0072 0.0369
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0422 0.0464 0.0661
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0041 0.0039
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0027 0.0003 0.0001
Brugia malayi PHD-finger family protein 0.0116 0.0106 0.054
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0048 0.0027 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Echinococcus multilocularis ecdysone induced protein 78C 0.012 0.011 0.0109
Trichomonas vaginalis importin beta-1, putative 0.0053 0.0033 0.0156
Plasmodium vivax endoplasmin, putative 0.0071 0.0053 0.2427
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0037 0.0014 0.0012
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0049 0.0028 0.2799
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0636 0.0713 0.2858
Schistosoma mansoni endoplasmin 0.0071 0.0053 0.0207
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0031 0.0007 0.016
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0057 0.0277
Schistosoma mansoni terminal deoxycytidyl transferase 0.0041 0.0019 0.0069
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0019 0.048
Brugia malayi photoreceptor-specific nuclear receptor 0.012 0.011 0.0563
Brugia malayi neuropeptide F receptor 0.0037 0.0014 0.0072
Echinococcus granulosus allatostatin A receptor 0.0037 0.0014 0.0018
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0065 0.0047 0.0065
Loa Loa (eye worm) tnks protein 0.0035 0.0011 0.0058
Trichomonas vaginalis heat shock protein, putative 0.0056 0.0036 0.0174
Entamoeba histolytica hypothetical protein 0.0035 0.0011 0.0221
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0119 0.0109 0.0107
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0032 0.0043
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Loa Loa (eye worm) glutaminase 0.1705 0.196 1
Brugia malayi Latrophilin receptor protein 2 0.017 0.0169 0.0863
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0048 0.0027 0.073
Trypanosoma brucei polo-like protein kinase 0.0113 0.0103 0.2854
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Echinococcus granulosus neuropeptide s receptor 0.0037 0.0014 0.0018
Brugia malayi nuclear receptor NHR-88 0.012 0.011 0.0563
Schistosoma mansoni hypothetical protein 0.0037 0.0014 0.005
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0027 0.0003 0.0004
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0032 0.0046
Schistosoma mansoni opsin-like receptor 0.0037 0.0014 0.005
Schistosoma mansoni bromodomain containing protein 0.0278 0.0295 0.1178
Trypanosoma brucei heat shock protein 90, putative 0.0071 0.0053 0.1461
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.0014 0.005
Schistosoma mansoni ap endonuclease 0.006 0.0041 0.0158
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0014 0.0269
Loa Loa (eye worm) MBCTL1 0.0119 0.0109 0.0557
Trypanosoma cruzi PAB1-binding protein , putative 0.0081 0.0065 0.178
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.012 0.011 0.0437
Loa Loa (eye worm) hypothetical protein 0.0063 0.0045 0.0227
Schistosoma mansoni nuclear hormone receptor 0.0056 0.0037 0.014
Schistosoma mansoni neuropeptide F-like receptor 0.0037 0.0014 0.005
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0049 0.0028 0.0132
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0157 0.0154 0.4302
Echinococcus multilocularis muscleblind protein 1 0.0145 0.0139 0.0138
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Echinococcus granulosus histone lysine methyltransferase setb 0.0171 0.017 0.0241
Brugia malayi WGR domain containing protein 0.047 0.0519 0.2647
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Echinococcus granulosus poly (ADP ribose) polymerase 0.0073 0.0056 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0033 0.0156
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0034 0.001 0.0051
Leishmania major citrate synthase, putative 0.0046 0.0024 0.0683
Schistosoma mansoni hypothetical protein 0.1447 0.1659 0.6663
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0171 0.017 0.0677
Trichomonas vaginalis heat shock protein, putative 0.0056 0.0036 0.0174
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0053 0.0033 0.0156
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.0019 0.0531
Leishmania major hypothetical protein, conserved 0.0081 0.0065 0.1824
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0037 0.0014 0.0072
Mycobacterium ulcerans hypothetical protein 0.0174 0.0174 0.0249
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.07 0.0788 0.402
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0027 0.0003 0.0002
Echinococcus granulosus Nuclear hormone receptor HR96 0.0056 0.0037 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.001 0.0039
Echinococcus multilocularis expressed protein 0.0027 0.0003 0.0001
Schistosoma mansoni biogenic amine receptor 0.0037 0.0014 0.005
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.012 0.011 0.0155
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.006 0.0041 0.0059
Loa Loa (eye worm) hypothetical protein 0.0537 0.0598 0.305
Schistosoma mansoni methyl-cpg binding protein mbd 0.0072 0.0055 0.0213
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Onchocerca volvulus Serine\/threonine kinase homolog 0.0113 0.0103 0.1188
Loa Loa (eye worm) acetyltransferase 0.0158 0.0155 0.0793
Echinococcus granulosus retinoic acid receptor rxr beta a 0.012 0.011 0.0155
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0027 0.0003 0.0014
Onchocerca volvulus Glucosylceramidase homolog 0.0178 0.0178 0.2063
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0031 0.0007 0.0025
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Brugia malayi GnHR receptor homolog 0.0037 0.0014 0.0072
Schistosoma mansoni inositol monophosphatase 0.0037 0.0014 0.005
Giardia lamblia Grp94/Hsp90 0.0056 0.0036 0.0894
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0056 0.0036 0.4438
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0056 0.0036 0.0971
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0636 0.0713 0.3637
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.047 0.0519 1
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0041 0.0156
Trichomonas vaginalis bromodomain-containing protein, putative 0.0054 0.0033 0.0159
Toxoplasma gondii ribosomal protein RPL19 0.0031 0.0007 0.0074
Schistosoma mansoni neuropeptide receptor 0.0037 0.0014 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0047 0.0229
Echinococcus multilocularis ribosomal protein L19 0.0031 0.0007 0.0006
Echinococcus granulosus G protein coupled receptor 139 0.0037 0.0014 0.0018
Leishmania major heat shock protein, putative 0.0029 0.0005 0.0127
Trypanosoma cruzi target of rapamycin kinase 3 0.0056 0.0036 0.0953
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0027 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Echinococcus multilocularis tar DNA binding protein 0.0598 0.0669 0.0667
Loa Loa (eye worm) MH2 domain-containing protein 0.0389 0.0425 0.2167
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0036 0.0171
Trichomonas vaginalis glutaminase, putative 0.1705 0.196 1
Loa Loa (eye worm) TAR-binding protein 0.0598 0.0669 0.3412
Leishmania major 60S ribosomal protein L19, putative 0.0031 0.0007 0.0203
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0519 0.0576 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0144
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.012 0.011 0.0109
Brugia malayi tailless protein 0.0056 0.0037 0.0187
Loa Loa (eye worm) hypothetical protein 0.0367 0.0399 0.2038
Onchocerca volvulus 0.0056 0.0037 0.0423
Schistosoma mansoni cpg binding protein 0.0138 0.0132 0.0523
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0033 0.0156
Schistosoma mansoni heat shock protein 0.0071 0.0053 0.0207
Trichomonas vaginalis set domain proteins, putative 0.0766 0.0865 0.4406
Brugia malayi AKH receptor 0.0037 0.0014 0.0072
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Schistosoma mansoni glutaminase 0.1705 0.196 0.7872
Echinococcus multilocularis heat shock protein 90 0.0071 0.0053 0.0051
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0063 0.0045 0.0043
Trypanosoma brucei citrate synthase, putative 0.0046 0.0024 0.0652
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0037 0.0014 0.0018
Brugia malayi exodeoxyribonuclease III family protein 0.006 0.0041 0.021
Echinococcus multilocularis geminin 0.1447 0.1659 0.1658
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0041 0.1135
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0056 0.0037 0.0187
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0333 0.169
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Schistosoma mansoni neuropeptide receptor 0.0037 0.0014 0.005
Loa Loa (eye worm) neuropeptide F receptor 0.0037 0.0014 0.0072
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0178 0.09
Mycobacterium tuberculosis Conserved hypothetical protein 0.0174 0.0174 0.0249
Brugia malayi G-protein coupled receptor 0.0037 0.0014 0.0072
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.0064 0.1068
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0041 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0178 0.09
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0178 0.09
Schistosoma mansoni patched 1 0.0141 0.0136 0.0539
Schistosoma mansoni alpha-1 adrenergic receptor 0.0037 0.0014 0.005
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0031 0.0007 0.0025
Schistosoma mansoni tar DNA-binding protein 0.0598 0.0669 0.2681
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0331 0.0357 1
Brugia malayi heat shock protein 90 0.0071 0.0053 0.0271
Toxoplasma gondii hypothetical protein 0.0053 0.0033 0.0525
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.012 0.011 0.0109
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0037 0.0014 0.0163
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0027 0.0003 0.0001
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0031 0.0007 0.0151
Trypanosoma cruzi heat shock protein, putative 0.0029 0.0005 0.0075
Leishmania major phosphatidylinositol 3-kinase, putative 0.0034 0.001 0.0279
Onchocerca volvulus Bile acid receptor homolog 0.012 0.011 0.1276
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0063 0.0045 0.0227
Giardia lamblia Heat shock protein HSP 90-alpha 0.0071 0.0053 0.1408
Brugia malayi MH2 domain containing protein 0.0389 0.0425 0.2167
Onchocerca volvulus DNA ligase 3 homolog 0.0061 0.0042 0.049
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Schistosoma mansoni coup transcription factor 0.012 0.011 0.0437
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0014 0.0071
Leishmania major DNA polymerase eta, putative 0.0096 0.0082 0.2311
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.006 0.0041 0.1152
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.1698 0.1951 0.2793
Echinococcus granulosus poly adp ribose polymerase 2 0.0258 0.0272 0.0387
Toxoplasma gondii ATPase, AAA family protein 0.0049 0.0028 0.044
Brugia malayi putative neuropeptide receptor NPR1 0.0037 0.0014 0.0072
Schistosoma mansoni tankyrase 0.0035 0.0011 0.0039
Loa Loa (eye worm) DR-78 0.0056 0.0037 0.0187
Trypanosoma brucei Heat shock protein 83, putative 0.0071 0.0053 0.1461
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0021 0.0097
Brugia malayi glutaminase DH11.1 0.1705 0.196 1
Loa Loa (eye worm) hypothetical protein 0.0145 0.0139 0.0712
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0019 0.048
Echinococcus granulosus FTZ F1 alpha 0.012 0.011 0.0155
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0017 0.0077
Toxoplasma gondii target of rapamycin (TOR), putative 0.0053 0.0033 0.052
Trypanosoma brucei importin beta-1 subunit, putative 0.0066 0.0047 0.1298
Loa Loa (eye worm) hypothetical protein 0.012 0.011 0.0563
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0027 0.0003 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0014 0.034
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.012 0.011 0.0563
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0017 0.0077
Trypanosoma brucei heat shock protein, putative 0.0071 0.0053 0.1461
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0054 0.0033 0.053
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0027 0.0003 0.0002
Plasmodium vivax replication factor C subunit 1, putative 0.0049 0.0028 0.1219
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0636 0.0713 0.1018
Loa Loa (eye worm) CXXC zinc finger family protein 0.0123 0.0114 0.0582
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0029 0.0005 0.0003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.012 0.011 0.0109
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0037 0.0014 0.0072
Echinococcus granulosus methyl CpG binding domain protein 2 0.0072 0.0055 0.0076
Onchocerca volvulus 0.0037 0.0014 0.0163
Schistosoma mansoni microtubule-associated protein tau 0.2159 0.2489 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0331 0.0357 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0037 0.0014 0.0012
Brugia malayi Probable citrate synthase, mitochondrial precursor, putative 0.0046 0.0024 0.0124
Onchocerca volvulus 0.0037 0.0014 0.0163
Brugia malayi nuclear receptor RXR 0.0063 0.0045 0.0227
Brugia malayi orphan nuclear receptor NR2E1 0.0056 0.0037 0.0187
Trypanosoma cruzi heat shock protein 90, putative 0.0042 0.0019 0.0493
Giardia lamblia Fructose-bisphosphate aldolase 0.0311 0.0333 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0037 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.0155 0.0151 0.0771
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.008 0.0064 0.0329
Brugia malayi beta-lactamase family protein 0.0205 0.021 0.107
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0072 0.0055 0.0053
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0205 0.021 0.03
Echinococcus multilocularis SAM and MBT domain containing protein 0.0104 0.0092 0.0091
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus multilocularis serine protein kinase ATM 0.0033 0.0009 0.0008
Echinococcus multilocularis serotonin receptor 0.0037 0.0014 0.0012
Schistosoma mansoni biogenic amine (5HT) receptor 0.0037 0.0014 0.005
Brugia malayi F/Y-rich N-terminus family protein 0.0049 0.0028 0.0144
Echinococcus granulosus cpg binding protein 0.0138 0.0132 0.0186
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0041 0.0058
Loa Loa (eye worm) hypothetical protein 0.0096 0.0082 0.0421
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0263 0.0277 0.0275
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.012 0.011 0.0563
Schistosoma mansoni endoplasmin 0.0071 0.0053 0.0207
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0032 0.0046
Plasmodium vivax unspecified product 0.0046 0.0024 0.1035
Echinococcus multilocularis nuclear receptor nhr 48 0.0056 0.0037 0.0035
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0093 0.0079 0.0111
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0067 0.0049 0.0808
Echinococcus granulosus sterol regulatory element binding protein 0.0141 0.0136 0.0192
Echinococcus granulosus g protein coupled receptor 0.0037 0.0014 0.0018
Trypanosoma brucei DNA repair protein, putative 0.0061 0.0042 0.1157
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0178 0.09
Entamoeba histolytica G protein alpha subunit, putative 0.0027 0.0003 0.0052
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0056 0.0037 0.0035
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0019 0.048
Loa Loa (eye worm) hypothetical protein 0.033 0.0355 0.1813
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0099 0.0086 0.1452
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0333 0.169
Trypanosoma brucei unspecified product 0.0041 0.0019 0.05
Brugia malayi Bromodomain containing protein 0.0327 0.0353 0.1799
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0037 0.0014 0.0018
Trypanosoma brucei heat shock protein, putative 0.0071 0.0053 0.1461
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0019 0.05
Echinococcus granulosus thyroid hormone receptor alpha 0.0056 0.0037 0.005
Schistosoma mansoni hypothetical protein 0.1447 0.1659 0.6663
Schistosoma mansoni poly [ADP-ribose] polymerase 0.047 0.0519 0.2078
Schistosoma mansoni zinc finger protein 0.0093 0.008 0.0313
Brugia malayi RNA, U transporter 1 0.0187 0.0188 0.0962
Echinococcus multilocularis dna polymerase eta 0.0096 0.0082 0.0081
Brugia malayi TAR-binding protein 0.0598 0.0669 0.3412
Toxoplasma gondii histone lysine methyltransferase SET1 0.025 0.0262 0.4526
Brugia malayi hypothetical protein 0.0063 0.0045 0.0227
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0017 0.0077
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-31 0.012 0.011 0.0563
Echinococcus granulosus heat shock protein 0.0071 0.0053 0.0074
Schistosoma mansoni hypothetical protein 0.0087 0.0072 0.0284
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0014 0.0195
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0014 0.0012
Brugia malayi hypothetical protein 0.0063 0.0045 0.0227
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0636 0.0713 0.0711
Brugia malayi MH2 domain containing protein 0.0027 0.0002 0.0009
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.0064 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0021 0.0096
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0027 0.0003 0.0004
Trypanosoma brucei heat shock protein 84, putative 0.0029 0.0005 0.0095
Trypanosoma brucei ISWI complex protein 0.0065 0.0046 0.1264
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0056 0.0037 0.005
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0014 0.0071
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0009 0.0048
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0014 0.0012
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0049 0.0028 0.0132
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0333 0.169
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0036 0.0171
Leishmania major DNA polymerase eta, putative 0.0067 0.0049 0.1381
Loa Loa (eye worm) G-protein coupled receptor 0.0037 0.0014 0.0072
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0034 0.001 0.0227
Trypanosoma brucei unspecified product 0.0028 0.0004 0.008
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0037 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.0041 0.0019 0.0096
Trichomonas vaginalis D-aminoacylase, putative 0.0205 0.021 0.1059
Echinococcus multilocularis replication factor c subunit 1 0.0049 0.0028 0.0026
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0205 0.021 0.0836
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0258 0.0272 0.7603
Brugia malayi Tnks protein 0.0035 0.0011 0.0058
Loa Loa (eye worm) hypothetical protein 0.0205 0.021 0.107
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Toxoplasma gondii citrate synthase I 0.0046 0.0024 0.0373
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0027 0.0003 0.0002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0019 0.048
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0157 0.0154 0.4272
Schistosoma mansoni RAR-like nuclear receptor 0.012 0.011 0.0437
Schistosoma mansoni opsin-like receptor 0.0037 0.0014 0.005
Onchocerca volvulus 0.0104 0.0092 0.1067
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Schistosoma mansoni retinoic acid receptor RXR 0.012 0.011 0.0437
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0049 0.0028 0.0543
Loa Loa (eye worm) hypothetical protein 0.0358 0.0388 0.1979
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Brugia malayi Muscleblind-like protein 0.0145 0.0139 0.0712
Schistosoma mansoni alpha glucosidase 0.0037 0.0014 0.0049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0333 0.169
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.008 0.0064 0.1854
Brugia malayi mbt repeat family protein 0.0104 0.0092 0.0471
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0021 0.0098
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Brugia malayi mbt repeat family protein 0.0104 0.0092 0.0471
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0056 0.0037 0.014
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0144
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0056 0.0036 0.1001
Loa Loa (eye worm) hypothetical protein 0.0104 0.0092 0.0471
Loa Loa (eye worm) hypothetical protein 0.0063 0.0045 0.0227
Onchocerca volvulus 0.0027 0.0003 0.0031
Loa Loa (eye worm) CHromoDomain protein family member 0.0027 0.0002 0.0012
Trypanosoma brucei unspecified product 0.0028 0.0004 0.008
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0027 0.0003 0.0014
Brugia malayi Nuclear hormone receptor-like 1 0.0063 0.0045 0.0227
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0031 0.0007 0.0025
Mycobacterium leprae conserved hypothetical protein 0.0205 0.021 0.1074
Loa Loa (eye worm) heterochromatin protein 1 0.0074 0.0057 0.0289
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.017 0.0169 0.0167
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0037 0.0014 0.0012
Onchocerca volvulus 0.0027 0.0003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Schistosoma mansoni GTP-binding protein alpha subunit 0.0027 0.0003 0.0004
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.6015 0.6988 1
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0103 0.0513
Echinococcus granulosus lysosomal alpha glucosidase 0.0167 0.0165 0.0234
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0598 0.0669 0.3412
Loa Loa (eye worm) hypothetical protein 0.0205 0.021 0.107
Echinococcus multilocularis thymidine phosphorylase 0.6015 0.6988 0.6987
Echinococcus multilocularis fmrfamide receptor 0.0037 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Brugia malayi topoisomerase 0.0049 0.0028 0.0144
Echinococcus granulosus orexin receptor type 2 0.0037 0.0014 0.0018
Schistosoma mansoni alpha-glucosidase 0.0144 0.0138 0.0549
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0032 0.0164
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0034 0.001 0.0248
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0037 0.0014 0.0012
Onchocerca volvulus Neuropeptide F receptor homolog 0.0037 0.0014 0.0163
Brugia malayi CHE-14 protein 0.0141 0.0136 0.0693
Loa Loa (eye worm) hypothetical protein 0.0063 0.0045 0.0227
Brugia malayi larval opioid receptor 0.0037 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0144
Trypanosoma cruzi hypothetical protein, conserved 0.0205 0.021 0.5852
Brugia malayi nuclear receptor RXR 0.0056 0.0037 0.0187
Echinococcus granulosus neuropeptide Y receptor 0.0037 0.0014 0.0018
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0036 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0178 0.09
Brugia malayi Inositol-1 0.0037 0.0014 0.0072
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0287 0.1455
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0056 0.0036 0.1019
Entamoeba histolytica hypothetical protein 0.019 0.0192 0.3711
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0205 0.021 0.107
Trypanosoma cruzi DNA polymerase eta, putative 0.0096 0.0082 0.2269
Echinococcus granulosus 7tm_1 domain containing protein 0.0037 0.0014 0.0018
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0048 0.0027 0.0421
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.003 0.0142
Schistosoma mansoni biogenic amine receptor 0.0037 0.0014 0.005
Loa Loa (eye worm) latrophilin receptor protein 2 0.017 0.0169 0.0863
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.001 0.0039
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0014 0.0012
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0056 0.0037 0.0423
Echinococcus granulosus replication factor c subunit 1 0.0049 0.0028 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0021 0.0098
Brugia malayi Dopamine receptor 0.0037 0.0014 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-19 0.012 0.011 0.0563
Echinococcus granulosus polycomb protein SCMH1 0.0104 0.0092 0.013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0017 0.0077
Loa Loa (eye worm) hypothetical protein 0.0171 0.017 0.0868
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0037 0.0014 0.0012
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0041 0.0019 0.0069
Brugia malayi Importin beta-1 subunit 0.0066 0.0047 0.0242
Brugia malayi Nuclear hormone receptor-like 1 0.0063 0.0045 0.0227
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0205 0.021 0.03
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.012 0.011 0.0155
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Entamoeba histolytica 60S ribosomal protein L19, putative 0.0031 0.0007 0.014
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0014 0.006
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.008 0.0064 0.9855
Schistosoma mansoni 60S ribosomal protein L19 0.0031 0.0007 0.0022
Schistosoma mansoni hypothetical protein 0.0287 0.0305 0.122
Echinococcus multilocularis allatostatin A receptor 0.0037 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0028 0.0132
Brugia malayi Nuclear hormone receptor family member nhr-49 0.012 0.011 0.0563
Brugia malayi neuropeptide F receptor 0.0037 0.0014 0.0072
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0099 0.0086 0.0084
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0311 0.0333 0.6422
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0014 0.0018
Echinococcus multilocularis GPCR, family 2 0.017 0.0169 0.0167
Schistosoma mansoni amine GPCR 0.0037 0.0014 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0005 0.0013
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0167 0.0165 0.0844
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0056 0.0037 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.019 0.0957
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0041 0.0655
Loa Loa (eye worm) beta-lactamase 0.0205 0.021 0.107
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0041 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0636 0.0713 0.2858
Echinococcus multilocularis lysosomal alpha glucosidase 0.0167 0.0165 0.0164
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Schistosoma mansoni inositol monophosphatase 0.0037 0.0014 0.005
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0119 0.0109 0.0557
Schistosoma mansoni DNA polymerase eta 0.0096 0.0082 0.0325
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0014 0.0018
Echinococcus granulosus neuropeptide Y receptor 0.0037 0.0014 0.0018
Echinococcus granulosus histone acetyltransferase MYST2 0.0119 0.0109 0.0154
Giardia lamblia Heat shock protein HSP 90-alpha 0.0056 0.0036 0.0894
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0019 0.0027
Echinococcus multilocularis dnaJ subfamily B 0.0875 0.0991 0.099
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0034 0.001 0.0248
Loa Loa (eye worm) inositol-1 0.0037 0.0014 0.0072
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0258 0.0272 0.7603
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0037 0.0014 0.0018
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0103 0.0513
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Schistosoma mansoni hypothetical protein 0.017 0.0169 0.0673
Echinococcus granulosus microtubule associated protein 2 0.2159 0.2489 0.3561
Toxoplasma gondii heat shock protein HSP90 0.0071 0.0053 0.0875
Plasmodium falciparum endoplasmin, putative 0.0043 0.0021 0.2951
Onchocerca volvulus 0.0123 0.0114 0.132
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0056 0.0037 0.014
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0065 0.0047 0.024
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Entamoeba histolytica heat shock protein 90, putative 0.0071 0.0053 0.1024
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0063 0.0045 0.0172
Schistosoma mansoni amine GPCR 0.0037 0.0014 0.005
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0037 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0014 0.0366
Onchocerca volvulus 0.0037 0.0014 0.0163
Schistosoma mansoni neuropeptide receptor 0.0037 0.0014 0.005
Echinococcus granulosus heat shock protein 90 0.0056 0.0036 0.005
Echinococcus granulosus importin subunit beta 1 0.0066 0.0047 0.0065
Mycobacterium ulcerans heat shock protein 90 0.0056 0.0036 0.0052
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0023 0.0261
Echinococcus granulosus snurportin 1 0.07 0.0788 0.1125
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.012 0.011 0.0437
Echinococcus multilocularis protein dispatched 1 0.0161 0.0159 0.0157
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.0019 0.0027
Plasmodium vivax heat shock protein, putative 0.0029 0.0005 0.0076
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0017 0.0336
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0029 0.0005 0.0053
Loa Loa (eye worm) hypothetical protein 0.0176 0.0176 0.0896
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0014 0.0012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0017 0.0077
Trypanosoma cruzi polo-like protein kinase, putative 0.0113 0.0103 0.284
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus granulosus tar DNA binding protein 0.0598 0.0669 0.0955
Schistosoma mansoni tar DNA-binding protein 0.0598 0.0669 0.2681
Echinococcus granulosus dro:myosuppressin receptor 0.0037 0.0014 0.0018
Entamoeba histolytica hypothetical protein 0.0049 0.0028 0.0543
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0014 0.0061
Plasmodium vivax heat shock protein 86, putative 0.0071 0.0053 0.2427
Brugia malayi nuclear hormone receptor 0.012 0.011 0.0563
Onchocerca volvulus 0.0037 0.0014 0.0163
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0037 0.0014 0.0012
Schistosoma mansoni nuclear receptor 0.0056 0.0037 0.014
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.0064 1
Echinococcus multilocularis sterol regulatory element binding protein 0.0141 0.0136 0.0134
Echinococcus multilocularis muscleblind protein 0.0145 0.0139 0.0138
Loa Loa (eye worm) nuclear receptor NHR-67 0.0056 0.0037 0.0187
Loa Loa (eye worm) hypothetical protein 0.012 0.011 0.0563
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0019 0.0085
Echinococcus multilocularis Niemann Pick C1 protein 0.033 0.0355 0.0354
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Brugia malayi Niemann-Pick C1 protein precursor 0.033 0.0355 0.1813
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0037 0.0014 0.005
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0037 0.0014 0.005
Loa Loa (eye worm) transcription factor SMAD2 0.0389 0.0425 0.2167
Entamoeba histolytica hypothetical protein 0.0053 0.0033 0.0634
Loa Loa (eye worm) hypothetical protein 0.0141 0.0136 0.0693
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0103 0.0513
Mycobacterium leprae Probable lipase LipE 0.0205 0.021 0.1074
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0014
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0287 0.0305 0.0434
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.001 0.0039
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0271 0.0287 0.1465
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0041 0.0019 0.0097
Echinococcus granulosus muscleblind protein 0.0145 0.0139 0.0197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0033 0.0156
Echinococcus multilocularis zinc finger protein 0.0093 0.008 0.0078
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0025 0.0654
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Brugia malayi MH1 domain containing protein 0.0027 0.0002 0.0009
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0027 0.0003 0.0014
Trypanosoma cruzi ISWI complex protein 0.0065 0.0046 0.1246
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0036 0.0173
Schistosoma mansoni retinoid-x-receptor (RXR) 0.012 0.011 0.0437
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Echinococcus granulosus dna polymerase eta 0.0096 0.0082 0.0116
Brugia malayi nuclear hormone receptor 0.0056 0.0037 0.0187
Brugia malayi Nuclear hormone receptor family member nhr-1 0.012 0.011 0.0563
Loa Loa (eye worm) hypothetical protein 0.012 0.011 0.0563
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0061 0.0042 0.1157
Entamoeba histolytica serine/threonine protein kinase, putative 0.0113 0.0103 0.198
Loa Loa (eye worm) hypothetical protein 0.0066 0.0047 0.0242
Schistosoma mansoni growth hormone secretagogue receptor 0.0037 0.0014 0.005
Loa Loa (eye worm) hypothetical protein 0.0205 0.021 0.107
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0027 0.0003 0.0004
Brugia malayi RE15519p 0.0037 0.0014 0.0072
Brugia malayi latrophilin 2 splice variant baaae 0.0367 0.0399 0.2038
Echinococcus granulosus nuclear receptor 2DBD gamma 0.012 0.011 0.0155
Schistosoma mansoni biogenic amine (5HT) receptor 0.0037 0.0014 0.005
Brugia malayi follicle stimulating hormone receptor 0.0037 0.0014 0.0072
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0031 0.0007 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0019 0.0085
Schistosoma mansoni zinc finger protein 0.0065 0.0046 0.0179
Plasmodium falciparum ataxin-2 like protein, putative 0.0081 0.0065 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0152 0.0148 0.0146
Trypanosoma cruzi ISWI complex protein 0.0065 0.0046 0.1246
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0053 0.0033 0.0156
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.0333 0.169
Plasmodium falciparum replication factor C subunit 1, putative 0.0049 0.0028 0.4056
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0027 0.0003 0.0004
Trypanosoma brucei heat shock protein, putative 0.0071 0.0053 0.1461
Schistosoma mansoni hypothetical protein 0.0645 0.0723 0.2901
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0537 0.0598 0.305
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0019 0.0027
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0141 0.0136 0.0693
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0032 0.003
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0258 0.0272 0.027
Echinococcus granulosus somatostatin receptor 0.0037 0.0014 0.0018
Schistosoma mansoni tar DNA-binding protein 0.0598 0.0669 0.2681
Brugia malayi Nuclear hormone receptor family member nhr-40 0.012 0.011 0.0563
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.012 0.011 0.1276
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0158 0.0155 0.0618
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.012 0.011 0.0563
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0144
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0636 0.0713 0.3637
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0014 0.0018
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.1698 0.1951 0.2793
Brugia malayi Nuclear hormone receptor-like 1 0.012 0.011 0.0563
Schistosoma mansoni kinase 0.0057 0.0038 0.0145
Brugia malayi conserved hypotetical protein 0.0056 0.0037 0.0187
Schistosoma mansoni hypothetical protein 0.0036 0.0013 0.0046
Onchocerca volvulus 0.0037 0.0014 0.0163
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0048 0.0027 0.0138
Echinococcus granulosus histone acetyltransferase KAT2B 0.0054 0.0033 0.0045
Brugia malayi beta-lactamase 0.0205 0.021 0.107
Plasmodium vivax ataxin-2 like protein, putative 0.0081 0.0065 0.3005
Onchocerca volvulus 0.0037 0.0014 0.0163
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.012 0.011 0.0563
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0287 0.1455
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0152 0.0148 0.0212
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0205 0.021 0.0836
Brugia malayi Pre-SET motif family protein 0.0099 0.0086 0.044
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0103 0.0513
Plasmodium falciparum citrate synthase, mitochondrial, putative 0.0046 0.0024 0.3445
Trypanosoma cruzi Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0061 0.0042 0.1139
Onchocerca volvulus 0.0766 0.0865 1
Echinococcus granulosus tm gpcr rhodopsin 0.0037 0.0014 0.0018
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0263 0.0277 0.0394
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0027 0.0003 0.0001
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0113 0.0103 0.2878
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0119 0.0109 0.0154
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0016 0.0069
Loa Loa (eye worm) heat shock protein 75 0.0029 0.0005 0.0023
Schistosoma mansoni ap endonuclease 0.006 0.0041 0.0158
Echinococcus granulosus g protein coupled receptor 0.0037 0.0014 0.0018
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0258 0.0272 0.1086
Trypanosoma brucei heat shock protein 90, putative 0.0071 0.0053 0.1461
Echinococcus granulosus SAM and MBT domain containing protein 0.0104 0.0092 0.013
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0037 0.0014 0.0012
Echinococcus granulosus neuropeptides capa receptor 0.0037 0.0014 0.0018
Trichomonas vaginalis heat shock protein, putative 0.0056 0.0036 0.0174
Brugia malayi serine/threonine-protein kinase plk-2 0.0113 0.0103 0.0524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0047 0.0229
Echinococcus multilocularis sex peptide receptor 0.0037 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus multilocularis heat shock protein 90 0.0056 0.0036 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0033 0.0156
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0017 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Echinococcus granulosus tumor protein p63 0.037 0.0403 0.0574
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Entamoeba histolytica hypothetical protein 0.0035 0.0011 0.0221
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0099 0.0086 0.034
Echinococcus multilocularis g protein coupled receptor 0.0037 0.0014 0.0012
Onchocerca volvulus 0.0111 0.01 0.1159
Echinococcus granulosus ecdysone induced protein 78C 0.012 0.011 0.0155
Schistosoma mansoni hypothetical protein 0.0037 0.0014 0.005
Plasmodium vivax unspecified product 0.0046 0.0024 0.1035
Echinococcus multilocularis neuropeptide receptor 0.0037 0.0014 0.0012
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0037 0.0014 0.0072
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0041 0.0019 0.0017
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.019 0.0192 0.0273
Schistosoma mansoni histamine h1 receptor 0.0037 0.0014 0.005
Leishmania major 60S ribosomal protein L19, putative 0.0031 0.0007 0.0203
Trichomonas vaginalis heat shock protein, putative 0.0071 0.0053 0.026
Schistosoma mansoni hypothetical protein 0.0065 0.0046 0.0179
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Schistosoma mansoni hypothetical protein 0.0136 0.013 0.0515
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.012 0.011 0.0109
Schistosoma mansoni hypothetical protein 0.0037 0.0014 0.005
Giardia lamblia DINP protein human, muc B family 0.0041 0.0019 0.0359
Schistosoma mansoni adenoreceptor 0.0037 0.0014 0.005
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0223 0.0231 0.0922
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Echinococcus granulosus Nuclear hormone receptor HR96 0.0056 0.0037 0.005
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.017 0.0169 0.024
Trypanosoma brucei heat shock protein, putative 0.0071 0.0053 0.1461
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Toxoplasma gondii heat shock protein 75, putative 0.0029 0.0005 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-14 0.012 0.011 0.0563
Trypanosoma cruzi heat shock protein 90, putative 0.0056 0.0036 0.0971
Echinococcus multilocularis g-protein coupled receptor 0.0037 0.0014 0.0012
Brugia malayi hypothetical protein 0.0037 0.0014 0.0072
Echinococcus granulosus neuropeptides capa receptor 0.0037 0.0014 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Echinococcus granulosus thymidine phosphorylase 0.6015 0.6988 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0042 0.0216
Entamoeba histolytica hypothetical protein 0.0073 0.0056 0.1078
Loa Loa (eye worm) hypothetical protein 0.0191 0.0193 0.0986
Schistosoma mansoni hypothetical protein 0.017 0.0169 0.0673
Schistosoma mansoni tar DNA-binding protein 0.0598 0.0669 0.2681
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0034 0.001 0.0012
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0041 0.0019 0.0025
Trypanosoma brucei DNA polymerase eta, putative 0.0096 0.0082 0.2285
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Onchocerca volvulus 0.0155 0.0151 0.1747
Entamoeba histolytica exodeoxyribonuclease III, putative 0.006 0.0041 0.0793
Onchocerca volvulus 0.0037 0.0014 0.0163
Echinococcus granulosus chromobox protein 1 0.0074 0.0057 0.0079
Brugia malayi ImpB/MucB/SamB family protein 0.0096 0.0082 0.0421
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0014 0.0018
Schistosoma mansoni myosin xvIII 0.0037 0.0014 0.005
Trypanosoma cruzi citrate synthase, putative 0.0046 0.0024 0.0633
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0027 0.0002 0.0003
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0031 0.0007 0.0151
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0027 0.0003 0.0014
Loa Loa (eye worm) hypothetical protein 0.017 0.0169 0.0863
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0027 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0081 0.0065 0.0332
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0049 0.0028 0.0132
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0636 0.0713 0.1018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0009 0.0037
Onchocerca volvulus 0.0205 0.021 0.2424
Plasmodium falciparum heat shock protein 90, putative 0.0029 0.0005 0.0251
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0019 0.0017
Trichomonas vaginalis glucosylceramidase, putative 0.0188 0.019 0.0957
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Schistosoma mansoni nuclear hormone receptor 0.012 0.011 0.0437
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0205 0.021 0.107
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0014 0.006
Trichomonas vaginalis ran, putative 0.0048 0.0027 0.0127
Loa Loa (eye worm) MH2 domain-containing protein 0.0027 0.0002 0.0009
Onchocerca volvulus 0.0205 0.021 0.2424
Trypanosoma cruzi heat shock protein 90, putative 0.0071 0.0053 0.1443
Echinococcus multilocularis chromobox protein 1 0.0074 0.0057 0.0055
Leishmania major DNA repair protein, putative 0.0061 0.0042 0.1186
Echinococcus granulosus tm gpcr rhodopsin 0.0037 0.0014 0.0018
Onchocerca volvulus 0.0037 0.0014 0.0163
Brugia malayi G-protein coupled receptor 0.0037 0.0014 0.0072
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0037 0.0014 0.0018
Echinococcus multilocularis orexin receptor type 2 0.0037 0.0014 0.0012
Schistosoma mansoni alpha-glucosidase 0.0144 0.0138 0.0549
Echinococcus granulosus poly (ADP ribose) polymerase 0.0073 0.0056 0.0078
Echinococcus multilocularis FTZ F1 alpha 0.012 0.011 0.0109
Plasmodium falciparum importin beta, putative 0.0066 0.0047 0.7142
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0103 0.0513
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0056 0.0036 0.0052
Loa Loa (eye worm) hypothetical protein 0.0049 0.0028 0.0144
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0036 0.0173
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0014 0.0391
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0011 0.0047
Schistosoma mansoni ran 0.0048 0.0027 0.0102
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0027 0.0003 0.0004
Onchocerca volvulus 0.0037 0.0014 0.0163
Schistosoma mansoni opsin-like receptor 0.0037 0.0014 0.005
Brugia malayi ORL1-like opioid receptor 0.0037 0.0014 0.0072
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0019 0.05
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.0025 0.0673
Echinococcus granulosus nibrin 0.0049 0.0028 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0024 0.0112
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.017 0.0169 0.0863
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0014 0.006
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.0064 0.0092
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Mycobacterium tuberculosis Probable lipase LipD 0.0205 0.021 0.03
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0014
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0014 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0178 0.09
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0065 0.0047 0.132
Trypanosoma cruzi heat shock protein 85, putative 0.0056 0.0036 0.0971
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0042 0.0019 0.0025
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0108 0.0097 0.0095
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0027 0.0003 0.0004
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0057 0.0277
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0033 0.0156
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0041 0.1846
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0027 0.0003 0.0001
Treponema pallidum fructose-bisphosphate aldolase 0.0311 0.0333 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0037 0.0014 0.0012
Trypanosoma brucei importin beta-1 subunit, putative 0.0066 0.0047 0.1298
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0027 0.0003 0.0014
Schistosoma mansoni ran 0.0048 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Loa Loa (eye worm) hypothetical protein 0.012 0.011 0.0563
Leishmania major DNA polymerase kappa, putative 0.0041 0.0019 0.0531
Toxoplasma gondii heat shock protein 90, putative 0.0071 0.0053 0.0875
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0311 0.0333 0.6422
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0033 0.0009 0.0212
Loa Loa (eye worm) steroid hormone receptor 0.012 0.011 0.0563
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0027 0.0003 0.0002
Leishmania major hypothetical protein, conserved 0.0205 0.021 0.5874
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Echinococcus multilocularis somatostatin receptor 0.0037 0.0014 0.0012
Echinococcus granulosus tankyrase 0.0035 0.0011 0.0014
Echinococcus granulosus biogenic amine 5HT receptor 0.0037 0.0014 0.0018
Echinococcus granulosus peptide allatostatin:somatostatin 0.0037 0.0014 0.0018
Echinococcus granulosus endoplasmin 0.0056 0.0036 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Toxoplasma gondii FATC domain-containing protein 0.0033 0.0009 0.0113
Trypanosoma cruzi heat shock protein 85, putative 0.0071 0.0053 0.1443
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0019 0.05
Echinococcus multilocularis protein patched 0.0141 0.0136 0.0134
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0004 0.008
Loa Loa (eye worm) hypothetical protein 0.012 0.011 0.0563
Plasmodium falciparum 60S ribosomal protein L19 0.0031 0.0007 0.0687
Schistosoma mansoni thyroid hormone receptor 0.0406 0.0445 0.1781
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0028 0.0132
Echinococcus granulosus dnaJ subfamily B 0.0875 0.0991 0.1416
Trypanosoma cruzi heat shock protein 85, putative 0.0071 0.0053 0.1443
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0023 0.0104
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0014 0.0346
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0027 0.0003 0.0014
Onchocerca volvulus 0.0205 0.021 0.2424
Echinococcus multilocularis lysosomal alpha glucosidase 0.0167 0.0165 0.0164
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.012 0.011 0.0563
Entamoeba histolytica hypothetical protein 0.0035 0.0011 0.0221
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.017 0.0169 0.0167
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0034 0.0011 0.0035
Toxoplasma gondii Hsp90 domain-containing protein 0.0029 0.0005 0.0027
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0019 0.05
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0056 0.0037 0.005
Trichomonas vaginalis replication factor C large subunit, putative 0.0049 0.0028 0.0132
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0033 0.0009 0.0232
Brugia malayi Endoplasmin precursor 0.0071 0.0053 0.0271
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0027 0.0003 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Brugia malayi ecdysteroid receptor 0.012 0.011 0.0563
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0033 0.0156
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0335 0.0361 0.1446
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0036 0.0171
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1308 0.1497 0.2142
Schistosoma mansoni hypothetical protein 0.0136 0.013 0.0515
Brugia malayi hypothetical protein 0.0056 0.0037 0.0187
Brugia malayi G-protein alpha subunit 0.0027 0.0003 0.0014
Mycobacterium tuberculosis Probable esterase LipL 0.0205 0.021 0.03
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0019 0.0083
Schistosoma mansoni sex comb on midleg homolog 0.0104 0.0092 0.0364
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0287 0.1455
Leishmania major hypothetical protein, conserved 0.0061 0.0042 0.1186
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0028 0.0132
Loa Loa (eye worm) hypothetical protein 0.0063 0.0045 0.0227
Onchocerca volvulus 0.0037 0.0014 0.0163
Echinococcus multilocularis fmrfamide receptor 0.0037 0.0014 0.0012
Toxoplasma gondii exonuclease III APE 0.006 0.0041 0.0666
Echinococcus granulosus serotonin receptor 0.0037 0.0014 0.0018
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0027 0.0003 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0028 0.074
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0028 0.0003 0.0015
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0027 0.0003 0.0004
Echinococcus granulosus GTP binding nuclear protein Ran 0.0048 0.0027 0.0036
Brugia malayi Hsp90 protein 0.0029 0.0005 0.0023
Loa Loa (eye worm) hypothetical protein 0.0027 0.0003 0.0014
Entamoeba histolytica hypothetical protein 0.0035 0.0011 0.0221
Onchocerca volvulus 0.0037 0.0014 0.0163
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.012 0.011 0.0563
Trypanosoma cruzi polo-like protein kinase, putative 0.0113 0.0103 0.284
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0027 0.0003 0.0014
Brugia malayi sulfakinin receptor protein 0.0037 0.0014 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Echinococcus granulosus tm gpcr rhodopsin 0.0037 0.0014 0.0018
Echinococcus multilocularis dro:myosuppressin receptor 0.0037 0.0014 0.0012
Trichomonas vaginalis penicillin-binding protein, putative 0.0205 0.021 0.1059
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0025 0.0654
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0028 0.074
Brugia malayi nuclear hormone receptor family member nhr-6 0.0056 0.0037 0.0187
Brugia malayi hypothetical protein 0.0049 0.0028 0.0144
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0037 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0104 0.0092 0.0364
Mycobacterium ulcerans beta-lactamase 0.0205 0.021 0.03
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0048 0.0027 0.0711
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0037 0.0014 0.005
Plasmodium vivax citrate synthase, mitochondrial precursor, putative 0.0046 0.0024 0.1035
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0014 0.005
Plasmodium vivax 60S ribosomal protein L19, putative 0.0031 0.0007 0.0207
Trypanosoma cruzi FHA domain containing protein, putative 0.0049 0.0028 0.074
Trichomonas vaginalis glucosylceramidase, putative 0.0271 0.0287 0.1455
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0065 0.0047 0.1274
Trichomonas vaginalis D-aminoacylase, putative 0.0205 0.021 0.1059
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0017 0.2327
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0049 0.0028 0.074
Echinococcus multilocularis microtubule associated protein 2 0.2159 0.2489 0.2488
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0056 0.0037 0.0187
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0037 0.0014 0.0012
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0041 0.0056
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0005
Echinococcus multilocularis snurportin 1 0.07 0.0788 0.0786
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.006 0.0041 0.0056
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0152 0.0148 0.0209
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0113 0.0103 0.0524
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0111 0.01 0.0396
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.0014 0.005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.001
Loa Loa (eye worm) heat shock protein 90 0.0071 0.0053 0.0271
Brugia malayi Nuclear hormone receptor E75 0.0056 0.0037 0.0187
Echinococcus multilocularis nibrin 0.0049 0.0028 0.0026
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0054 0.0033 0.053
Loa Loa (eye worm) mbt repeat family protein 0.0104 0.0092 0.0471
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.012 0.011 0.0109
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Trypanosoma brucei heat shock protein, putative 0.0071 0.0053 0.1461
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0041 0.0058
Mycobacterium ulcerans esterase/lipase LipP 0.0205 0.021 0.03
Entamoeba histolytica zinc finger protein, putative 0.0035 0.0011 0.0221
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0065 0.0047 0.1274
Brugia malayi Nuclear hormone receptor family member nhr-25 0.012 0.011 0.0563
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trypanosoma cruzi DNA repair protein, putative 0.0061 0.0042 0.1139
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.019 0.0192 0.0191
Echinococcus granulosus neuropeptide receptor 0.0037 0.0014 0.0018
Leishmania major heat shock protein 83-1 0.0071 0.0053 0.1489
Echinococcus granulosus neuropeptide receptor 0.0037 0.0014 0.0018
Schistosoma mansoni amine GPCR 0.0037 0.0014 0.005
Loa Loa (eye worm) hypothetical protein 0.0205 0.021 0.107
Echinococcus granulosus expressed conserved protein 0.031 0.0332 0.0473
Brugia malayi nuclear receptor NHR-67 0.0056 0.0037 0.0187
Schistosoma mansoni peptidase Clp (S14 family) 0.008 0.0064 0.0251
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0027 0.0003 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0205 0.021 0.5852
Plasmodium falciparum ataxin-2 like protein, putative 0.0081 0.0065 1
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0103 0.0406
Leishmania major hypothetical protein, conserved 0.0065 0.0046 0.1293
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.001 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0004 0.008
Echinococcus granulosus poly (ADP ribose) polymerase 0.0073 0.0056 0.0078
Trypanosoma cruzi Heat shock protein 83, putative 0.0071 0.0053 0.1443
Onchocerca volvulus Protein ultraspiracle homolog 0.012 0.011 0.1276
Plasmodium falciparum heat shock protein 90, putative 0.0029 0.0005 0.0251
Loa Loa (eye worm) hypothetical protein 0.0056 0.0037 0.0187
Brugia malayi Smad1 0.0027 0.0002 0.0009
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0014 0.0346
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0072
Trypanosoma cruzi DNA polymerase eta, putative 0.0067 0.0049 0.1335
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0037 0.0014 0.0012
Schistosoma mansoni methyl-cpg binding protein mbd 0.0072 0.0055 0.0213
Echinococcus multilocularis chromobox protein 1 0.0074 0.0057 0.0055
Brugia malayi G protein-coupled receptor F59B2.13 0.0037 0.0014 0.0072
Loa Loa (eye worm) citrate synthase 0.0046 0.0024 0.0124
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0037 0.0988
Echinococcus multilocularis endoplasmin 0.0056 0.0036 0.0035
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0065 0.0047 0.0908
Toxoplasma gondii ABC1 family protein 0.0205 0.021 0.3606
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0674 0.0757 0.3861
Brugia malayi Melatonin receptor type 1A 0.0037 0.0014 0.0072
Onchocerca volvulus 0.0032 0.0009 0.0098
Schistosoma mansoni hypothetical protein 0.0875 0.0991 0.3977
Mycobacterium ulcerans glutaminase 0.1705 0.196 0.2805
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0014 0.002

Activities

Activity type Activity value Assay description Source Reference
Change (functional) = -13.4 % Mean change in heart rate recorded 14 min after the administration of compound. ChEMBL. 3005568
EC25 (functional) = 25.8 ug ml-1 Concentration required to reduce maximum following frequencu (MFF) of isolated guinea pig atria by 25% ChEMBL. 3005568
ED50 (functional) 0 mg kg-1 ED 50 value against aconitine-induced arrhythmias in mice; IA is Inactive ChEMBL. 3005568
ED50 (functional) < 2 mg kg-1 Effective dose of the compound that antagonized arrhythmias evoked by coronary artery ligation in the rat was measured at 2.0 mg/kg dose ChEMBL. 3005568
Heart rate (functional) = 335 beats min-1 Effect on heart rate after isoprenaline induced tachycardia in the anesthetized rat at 2 mg/kg dose ChEMBL. 3005568
Heart rate (functional) = 335 beats min-1 Effect of the compound on heart rate on 1 min post isoprenaline induced tachycardia in the anesthetized rat at 2.0 mg/kg dose. ChEMBL. 3005568
Heart rate (functional) = 387 beats min-1 Effect on heart rate before isoprenaline induced tachycardia in the anesthetized rat at 2 mg/kg dose ChEMBL. 3005568
Increase (functional) = 0 % Maximum increase in heart rate evoked by isoprenaline. ChEMBL. 3005568
VF (functional) = 0 % Antagonism of Ventricular Fibrilloflutter (VF) evoked by coronary artery ligation in the rat measured at 2 mg/kg dose ChEMBL. 3005568

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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