Detailed information for compound 1357944

Basic information

Technical information
  • TDR Targets ID: 1357944
  • Name: 2-ethyl-4-[4-(furan-2-carbonyl)piperazine-1-c arbonyl]-6,7-dimethoxyisoquinolin-1-one
  • MW: 439.461 | Formula: C23H25N3O6
  • H donors: 0 H acceptors: 3 LogP: 1.33 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc2c(cn(c(=O)c2cc1OC)CC)C(=O)N1CCN(CC1)C(=O)c1ccco1
  • InChi: 1S/C23H25N3O6/c1-4-24-14-17(15-12-19(30-2)20(31-3)13-16(15)21(24)27)22(28)25-7-9-26(10-8-25)23(29)18-6-5-11-32-18/h5-6,11-14H,4,7-10H2,1-3H3
  • InChiKey: XMGJVZHTVUPLGI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-ethyl-4-[4-(furan-2-carbonyl)piperazine-1-carbonyl]-6,7-dimethoxy-isoquinolin-1-one
  • 2-ethyl-4-[[4-(2-furyl-oxomethyl)-1-piperazinyl]-oxomethyl]-6,7-dimethoxy-1-isoquinolinone
  • 2-ethyl-4-[4-(furan-2-carbonyl)piperazine-1-carbonyl]-6,7-dimethoxy-isocarbostyril
  • 2-ethyl-4-(4-furan-2-ylcarbonylpiperazin-1-yl)carbonyl-6,7-dimethoxy-isoquinolin-1-one
  • MLS000878932
  • 2-ethyl-4-{[4-(2-furoyl)piperazin-1-yl]carbonyl}-6,7-dimethoxyisoquinolin-1(2H)-one
  • MLS000086160
  • SMR000021669
  • EU-0087356

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Homo sapiens tumor protein p53 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni serine/threonine protein kinase 0.0458 0.0229 0.0564
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0465 0.0237 0.0241
Schistosoma mansoni septate junction protein 0.0276 0.0026 0.0065
Plasmodium falciparum casein kinase 1 0.0642 0.0434 0.4156
Loa Loa (eye worm) TK/DDR protein kinase 0.0328 0.0084 0.0085
Brugia malayi putative serine/threonine kinase SADA gamma 0.0367 0.0128 0.013
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.1191 0.1045 0.106
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1108 0.0952 0.0952
Entamoeba histolytica hypothetical protein 0.0255 0.0003 0.0032
Schistosoma mansoni protein kinase 0.0253 0.0001 0.0002
Onchocerca volvulus 0.0476 0.0249 0.0339
Brugia malayi Furin-like cysteine rich region family protein 0.1034 0.087 0.0883
Trypanosoma brucei SNF1-related protein kinases, putative 0.0367 0.0128 0.013
Loa Loa (eye worm) RhoGAP domain-containing protein 0.038 0.0142 0.0144
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0402 0.0167 0.0169
Brugia malayi hypothetical protein 0.0655 0.0448 0.0455
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0367 0.0128 0.013
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0128 0.1156
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.9116 0.9859 1
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0128 0.1156
Brugia malayi Immunoglobulin I-set domain containing protein 0.0276 0.0026 0.0027
Toxoplasma gondii histone kinase SNF1, putative 0.0367 0.0128 0.1227
Loa Loa (eye worm) hypothetical protein 0.0707 0.0506 0.0514
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.1471 0.1356 0.1375
Loa Loa (eye worm) TK/FER protein kinase 0.0812 0.0623 0.0632
Echinococcus granulosus hemicentin 1 0.0276 0.0026 0.0027
Schistosoma mansoni vesicular amine transporter 0.062 0.041 0.1009
Echinococcus multilocularis N chimaerin 0.038 0.0142 0.0142
Echinococcus granulosus tyrosine protein kinase Src64B 0.1108 0.0952 0.0966
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.038 0.0142 0.0142
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.057 0.0354 0.0359
Echinococcus granulosus protein kinase C gamma type 0.061 0.0398 0.0404
Onchocerca volvulus 0.2498 0.2499 0.3403
Schistosoma mansoni protein kinase 0.1662 0.1568 0.3861
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0761 0.0567 0.0575
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0464 0.0236 0.0239
Schistosoma mansoni tyrosine kinase 0.1359 0.1232 0.3032
Giardia lamblia Kinase, CMGC GSK 0.1191 0.1045 0.942
Schistosoma mansoni serine/threonine protein kinase 0.0606 0.0394 0.0971
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0442 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.062 0.041 0.0416
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.1155 0.1004 0.1019
Trichomonas vaginalis STE family protein kinase 0.0293 0.0045 0.0408
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0549 0.0331 0.0331
Schistosoma mansoni serine/threonine protein kinase 0.0402 0.0167 0.0411
Schistosoma mansoni tyrosine kinase 0.0489 0.0263 0.0648
Schistosoma mansoni serine/threonine protein kinase 0.0336 0.0094 0.0231
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.043 0.0198 0.0201
Trichomonas vaginalis AGC family protein kinase 0.061 0.0399 0.3595
Schistosoma mansoni Neurotrimin precursor (hNT) 0.062 0.041 0.1009
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0807 0.0617 0.0626
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0549 0.0331 0.3166
Leishmania major protein kinase A catalytic subunit isoform 1 0.0754 0.0558 0.0566
Trichomonas vaginalis AGC family protein kinase 0.0549 0.0331 0.2983
Trichomonas vaginalis AGC family protein kinase 0.0748 0.0551 0.497
Schistosoma mansoni serine/threonine protein kinase 0.1614 0.1515 0.3731
Brugia malayi serine/threonine protein kinase 6 0.0549 0.0331 0.0336
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0394 0.0158 0.0158
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0754 0.0558 0.5341
Plasmodium vivax casein kinase 1, putative 0.0642 0.0434 0.4156
Echinococcus granulosus N chimaerin 0.038 0.0142 0.0144
Giardia lamblia Kinase, PLK 0.0336 0.0094 0.0846
Loa Loa (eye worm) hypothetical protein 0.0655 0.0448 0.0455
Schistosoma mansoni tyrosine kinase 0.0629 0.0419 0.1031
Loa Loa (eye worm) TK/ALK protein kinase 0.5244 0.5552 0.5631
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0565 0.0348 0.0353
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.1108 0.0952 0.0952
Plasmodium vivax protein kinase Crk2 0.0465 0.0237 0.2271
Loa Loa (eye worm) AUR protein kinase 0.0549 0.0331 0.0336
Loa Loa (eye worm) hypothetical protein 0.0287 0.0039 0.004
Brugia malayi Protein kinase domain containing protein 0.0476 0.0249 0.0252
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0565 0.0348 0.0348
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.057 0.0354 0.0354
Schistosoma mansoni tyrosine kinase 0.0629 0.0419 0.1031
Schistosoma mansoni cell adhesion molecule 0.031 0.0065 0.016
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.038 0.0142 0.0349
Trichomonas vaginalis CAMK family protein kinase 0.0336 0.0094 0.0846
Entamoeba histolytica p21-activated kinase 0.044 0.0209 0.1998
Giardia lamblia Kinase, AGC PKA 0.0754 0.0558 0.5031
Brugia malayi Protein kinase domain containing protein 0.0364 0.0125 0.0127
Entamoeba histolytica hypothetical protein 0.1155 0.1004 0.9613
Echinococcus multilocularis epidermal growth factor receptor 0.1034 0.087 0.087
Brugia malayi casein kinase 1, delta 0.0642 0.0434 0.044
Echinococcus multilocularis hemicentin 1 0.0276 0.0026 0.0026
Plasmodium falciparum calcium-dependent protein kinase 3 0.057 0.0354 0.3386
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0579 0.0364 0.0364
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0312 0.0067 0.0068
Brugia malayi Protein kinase domain containing protein 0.0415 0.0182 0.0184
Loa Loa (eye worm) TK/FER protein kinase 0.0476 0.0249 0.0252
Loa Loa (eye worm) hypothetical protein 0.057 0.0354 0.0359
Trichomonas vaginalis CAMK family protein kinase 0.0336 0.0094 0.0846
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0324 0.008 0.0081
Echinococcus multilocularis PAK box P21 Rho binding 0.037 0.0131 0.0131
Giardia lamblia Kinase, CMGC GSK 0.1191 0.1045 0.942
Brugia malayi cyclin-dependent kinase 9 0.0375 0.0137 0.0139
Echinococcus multilocularis raf serine:threonine protein kinase 0.0408 0.0173 0.0173
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0336 0.0094 0.0094
Trichomonas vaginalis CMGC family protein kinase 0.0296 0.0049 0.0439
Loa Loa (eye worm) TK/EPH protein kinase 0.0342 0.0101 0.0102
Trichomonas vaginalis CMGC family protein kinase 0.0465 0.0237 0.2139
Schistosoma mansoni nephrin 0.031 0.0065 0.016
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0807 0.0617 0.0626
Echinococcus granulosus tyrosine protein kinase Srms 0.0928 0.0752 0.0762
Loa Loa (eye worm) TK protein kinase 0.0931 0.0755 0.0766
Echinococcus multilocularis dual specificity 0.0296 0.0049 0.0049
Onchocerca volvulus 0.0272 0.0023 0.0031
Entamoeba histolytica casein kinase, putative 0.0642 0.0434 0.4156
Trichomonas vaginalis AGC family protein kinase 0.0748 0.0551 0.497
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0458 0.0229 0.0229
Brugia malayi Protein kinase domain containing protein 0.0355 0.0115 0.0117
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.057 0.0354 0.0354
Plasmodium falciparum cGMP-dependent protein kinase 0.0291 0.0043 0.0414
Onchocerca volvulus 0.1191 0.1045 0.1423
Entamoeba histolytica protein kinase domain containing protein 0.1191 0.1045 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1108 0.0952 0.0952
Onchocerca volvulus 0.0929 0.0753 0.1026
Entamoeba histolytica tyrosin kinase, putative 0.0296 0.0049 0.0469
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0653 0.0446 0.1099
Echinococcus multilocularis basement membrane specific heparan sulfate 0.062 0.041 0.041
Loa Loa (eye worm) hypothetical protein 0.0747 0.0551 0.0559
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0682 0.0479 0.1179
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0128 0.1156
Echinococcus multilocularis casein kinase I delta 0.0642 0.0434 0.0434
Echinococcus granulosus tumor protein p63 0.0408 0.0174 0.0176
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.1249 0.1109 0.1125
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0642 0.0434 0.044
Schistosoma mansoni nck2/grb4 0.0401 0.0166 0.0409
Echinococcus granulosus casein kinase ii subunit alpha 0.0253 0.0001 0.0001
Trichomonas vaginalis STE family protein kinase 0.1249 0.1109 1
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1468 0.1352 0.1352
Schistosoma mansoni protein kinase 0.2542 0.2547 0.627
Entamoeba histolytica protein kinase, putative 0.0549 0.0331 0.3166
Loa Loa (eye worm) hypothetical protein 0.0977 0.0806 0.0818
Echinococcus multilocularis tyrosine protein kinase Abl 0.1355 0.1227 0.1227
Toxoplasma gondii casein kinase I 0.0642 0.0434 0.4156
Echinococcus granulosus serine:threonine protein kinase N2 0.1712 0.1624 0.1647
Entamoeba histolytica serine/threonine protein kinase, putative 0.0367 0.0128 0.1227
Schistosoma mansoni kinase 0.0375 0.0137 0.0338
Schistosoma mansoni serine/threonine protein kinase 0.0754 0.0558 0.1374
Echinococcus granulosus serine:threonine kinase SAD 1 0.0367 0.0128 0.013
Entamoeba histolytica protein kinase, putative 0.0748 0.0551 0.5276
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0754 0.0558 0.0566
Entamoeba histolytica PH domain containing protein kinase, putative 0.0361 0.0122 0.1163
Echinococcus granulosus Vam6:Vps39 protein 0.0682 0.0479 0.0486
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.031 0.0065 0.0065
Schistosoma mansoni protein kinase 0.043 0.0198 0.0488
Brugia malayi serine/threonine-protein kinase plk-2 0.0336 0.0094 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.0324 0.008 0.0198
Entamoeba histolytica cell division protein kinase 2, putative 0.0465 0.0237 0.2271
Leishmania major protein kinase A catalytic subunit 0.0754 0.0558 0.0566
Echinococcus multilocularis aurora kinase A 0.0549 0.0331 0.0331
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.9116 0.9859 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.031 0.0065 0.0066
Schistosoma mansoni serine/threonine protein kinase 0.1047 0.0885 0.2178
Schistosoma mansoni serine/threonine protein kinase 0.0322 0.0078 0.0191
Echinococcus granulosus tyrosine protein kinase Blk 0.0931 0.0755 0.0766
Entamoeba histolytica protein kinase, putative 0.0402 0.0167 0.1596
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.1249 0.1109 0.1125
Loa Loa (eye worm) hypothetical protein 0.0977 0.0806 0.0818
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0695 0.0493 0.0493
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0575 0.036 0.0365
Echinococcus granulosus dual specificity testis-specific protein kinase 0.043 0.0198 0.0201
Brugia malayi Protein kinase domain containing protein 0.0476 0.0249 0.0252
Trichomonas vaginalis CMGC family protein kinase 0.0465 0.0237 0.2139
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.1191 0.1045 0.106
Echinococcus granulosus dual specificity protein kinase clk2 0.1047 0.0885 0.0897
Echinococcus granulosus roundabout 2 0.031 0.0065 0.0066
Plasmodium falciparum serine/threonine protein kinase KIN 0.0367 0.0128 0.1227
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.031 0.0065 0.0066
Loa Loa (eye worm) TK/KIN16 protein kinase 0.3458 0.3566 0.3616
Brugia malayi SH2 domain containing protein 0.0812 0.0623 0.0632
Brugia malayi serine/threonine-protein kinase PAK 7 0.2232 0.2202 0.2234
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0754 0.0558 0.0566
Loa Loa (eye worm) hypothetical protein 0.0896 0.0716 0.0727
Giardia lamblia Kinase, CMGC DYRK 0.0296 0.0049 0.0439
Echinococcus multilocularis calcium dependent protein kinase 0.0392 0.0156 0.0156
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0565 0.0348 0.0353
Loa Loa (eye worm) hypothetical protein 0.0754 0.0558 0.0566
Loa Loa (eye worm) hypothetical protein 0.0917 0.0739 0.075
Brugia malayi serine/threonine-protein kinase 6 0.0549 0.0331 0.0336
Echinococcus multilocularis cyclin dependent kinase 9 0.0375 0.0137 0.0137
Entamoeba histolytica protein kinase, putative 0.0702 0.05 0.4788
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0315 0.007 0.0675
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.2542 0.2547 0.2583
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1614 0.1515 0.1537
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0433 0.0201 0.0204
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.2041 0.1989 0.1989
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0253 0.0001 0.0001
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.2309 0.2288 0.3116
Entamoeba histolytica protein kinase, putative 0.0416 0.0182 0.1741
Echinococcus multilocularis lachesin 0.0276 0.0026 0.0026
Echinococcus multilocularis roundabout 2 0.0931 0.0755 0.0755
Schistosoma mansoni serine/threonine-protein kinase 0.0361 0.0122 0.0299
Giardia lamblia Kinase, CMGC CLK 0.1047 0.0885 0.7975
Trichomonas vaginalis CMGC family protein kinase 0.0296 0.0049 0.0439
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.1191 0.1045 0.1045
Brugia malayi Immunoglobulin I-set domain containing protein 0.1657 0.1562 0.1585
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0128 0.1156
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.0043 0.0107
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1471 0.1356 0.1375
Loa Loa (eye worm) IKK protein kinase 0.6853 0.7343 0.7448
Echinococcus multilocularis c Jun NH2 terminal kinase 0.3006 0.3063 0.3063
Schistosoma mansoni serine/threonine protein kinase 0.0621 0.041 0.1011
Brugia malayi Tyrosine-protein kinase abl-1 0.1355 0.1227 0.1244
Brugia malayi STE20-like kinase MST 0.0426 0.0194 0.0197
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.1249 0.1109 0.1125
Loa Loa (eye worm) hypothetical protein 0.0682 0.0479 0.0486
Brugia malayi Protein kinase domain containing protein 0.1047 0.0885 0.0897
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0426 0.0194 0.0197
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0293 0.0045 0.0433
Loa Loa (eye worm) hypothetical protein 0.0929 0.0753 0.0764
Echinococcus multilocularis cyclin dependent kinase 1 0.0465 0.0237 0.0237
Schistosoma mansoni serine/threonine protein kinase 0.0367 0.0128 0.0316
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0754 0.0558 0.0566
Onchocerca volvulus Serine\/threonine kinase homolog 0.0336 0.0094 0.0128
Trichomonas vaginalis CMGC family protein kinase 0.0296 0.0049 0.0439
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0476 0.0249 0.2381
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1191 0.1045 0.106
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.9116 0.9859 1
Schistosoma mansoni rap gtpase-activating protein 0.0682 0.0479 0.1179
Giardia lamblia Kinase, CMGC CDK 0.0465 0.0237 0.2139
Loa Loa (eye worm) CMGC/CLK protein kinase 0.1047 0.0885 0.0897
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.1014 0.0848 0.086
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0754 0.0558 0.5341
Schistosoma mansoni tyrosine kinase 0.2266 0.224 0.5515
Echinococcus multilocularis cyclin dependent kinase 7 0.0606 0.0394 0.0394
Schistosoma mansoni serine/threonine protein kinase 0.0408 0.0173 0.0427
Trypanosoma cruzi aurora B kinase, putative 0.0549 0.0331 0.0336
Trypanosoma cruzi casein kinase, putative 0.0642 0.0434 0.044
Onchocerca volvulus 0.0476 0.0249 0.0339
Echinococcus multilocularis serine:threonine protein kinase N2 0.0565 0.0348 0.0348
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0682 0.0479 0.0486
Trypanosoma cruzi cdc2-related kinase 1 0.0465 0.0237 0.0241
Brugia malayi Stress-activated protein kinase jnk-1 0.3006 0.3063 0.3107
Echinococcus granulosus cyclin dependent kinase 19 0.1785 0.1705 0.1729
Onchocerca volvulus 0.0842 0.0656 0.0893
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0754 0.0558 0.0558
Loa Loa (eye worm) TK/FER protein kinase 0.0476 0.0249 0.0252
Echinococcus granulosus roundabout 2 0.0931 0.0755 0.0766
Trichomonas vaginalis CK1 family protein kinase 0.0642 0.0434 0.3915
Schistosoma mansoni serine/threonine kinase 0.0565 0.0348 0.0856
Brugia malayi Immunoglobulin I-set domain containing protein 0.031 0.0065 0.0066
Echinococcus multilocularis serine:threonine protein kinase 0.0312 0.0067 0.0067
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1155 0.1004 0.1019
Echinococcus multilocularis dual specificity 0.1155 0.1004 0.1004
Loa Loa (eye worm) inward rectifying k channel family protein 1 0.0747 0.0551 0.0559
Trypanosoma cruzi Protein kinase B 0.0361 0.0122 0.0123
Brugia malayi Prion-like- 0.0276 0.0026 0.0027
Giardia lamblia Kinase, AGC AKT 0.1021 0.0855 0.7709
Echinococcus multilocularis protein KINase family member (kin 25) 0.0821 0.0633 0.0633
Leishmania major protein kinase, putative 0.057 0.0354 0.0359
Loa Loa (eye worm) hypothetical protein 0.027 0.002 0.002
Trichomonas vaginalis AGC family protein kinase 0.0748 0.0551 0.497
Schistosoma mansoni serine/threonine protein kinase 0.0324 0.008 0.0196
Echinococcus multilocularis rho associated protein kinase 0.0842 0.0656 0.0656
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1407 0.1285 0.1303
Loa Loa (eye worm) hypothetical protein 0.062 0.041 0.0416
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0302 0.0056 0.0057
Entamoeba histolytica protein kinase, putative 0.0565 0.0348 0.3328
Entamoeba histolytica protein kinase, putative 0.1191 0.1045 1
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.057 0.0354 0.3386
Schistosoma mansoni adapter molecule crk 0.0401 0.0166 0.0409
Brugia malayi Serine/threonine-protein kinase SULU 0.2911 0.2958 0.3
Schistosoma mansoni serine/threonine protein kinase 0.0324 0.008 0.0198
Loa Loa (eye worm) hypothetical protein 0.0623 0.0413 0.0419
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0128 0.1156
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.1014 0.0848 0.086
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.1047 0.0885 0.0897
Echinococcus granulosus insulin receptor 0.1359 0.1232 0.1249
Onchocerca volvulus 0.6853 0.7343 1
Schistosoma mansoni serine/threonine protein kinase 0.0378 0.014 0.0345
Schistosoma mansoni serine/threonine protein kinase 0.0642 0.0434 0.1069
Schistosoma mansoni tyrosine kinase 0.3904 0.4062 1
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0296 0.0049 0.0049
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0793 0.0602 0.0611
Schistosoma mansoni serine/threonine protein kinase 0.0366 0.0127 0.0313
Trichomonas vaginalis STE family protein kinase 0.1249 0.1109 1
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0931 0.0755 0.0766
Echinococcus multilocularis peroxidasin 0.0279 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0773 0.058 0.0588
Trichomonas vaginalis CK1 family protein kinase 0.0642 0.0434 0.3915
Echinococcus granulosus cyclin dependent kinase 7 0.0606 0.0394 0.04
Brugia malayi protein-tyrosine kinase 0.0931 0.0755 0.0766
Brugia malayi hypothetical protein 0.0377 0.0139 0.0141
Trypanosoma cruzi casein kinase, putative 0.0642 0.0434 0.044
Brugia malayi Protein kinase domain containing protein 0.0639 0.0431 0.0437
Echinococcus granulosus TGF beta receptor type 1 0.0899 0.072 0.073
Schistosoma mansoni serine/threonine protein kinase 0.2911 0.2958 0.7283
Loa Loa (eye worm) hypothetical protein 0.0551 0.0333 0.0337
Plasmodium falciparum calcium-dependent protein kinase 2 0.057 0.0354 0.3386
Loa Loa (eye worm) hypothetical protein 0.0377 0.0139 0.0141
Trichomonas vaginalis CMGC family protein kinase 0.1191 0.1045 0.942
Brugia malayi Immunoglobulin I-set domain containing protein 0.3458 0.3566 0.3616
Echinococcus granulosus cyclin dependent kinase 9 0.041 0.0176 0.0178
Echinococcus multilocularis casein kinase I alpha 0.0642 0.0434 0.0434
Schistosoma mansoni roundabout 0.0276 0.0026 0.0065
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.1014 0.0848 0.086
Brugia malayi hypothetical protein 0.0682 0.0479 0.0486
Brugia malayi Immunoglobulin I-set domain containing protein 0.0276 0.0026 0.0027
Echinococcus granulosus beta-adrenergic receptor kinase 0.0322 0.0078 0.0079
Giardia lamblia Kinase, NEK 0.0293 0.0045 0.0408
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1191 0.1045 0.106
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0128 0.1156
Schistosoma mansoni neuroglian 0.031 0.0065 0.016
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0366 0.0127 0.0129
Schistosoma mansoni hypothetical protein 0.0377 0.0139 0.0342
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.233 0.2312 0.2345
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0128 0.1156
Trypanosoma cruzi cdc2-related kinase 3 0.0465 0.0237 0.0241
Loa Loa (eye worm) TK/FER protein kinase 0.0476 0.0249 0.0252
Brugia malayi Sex muscle abnormal protein 5 0.0401 0.0166 0.0168
Onchocerca volvulus 0.0476 0.0249 0.0339
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.062 0.041 0.1009
Echinococcus multilocularis contactin neuroglian septate junction protein 0.031 0.0065 0.0065
Echinococcus multilocularis casein kinase I alpha 0.0642 0.0434 0.0434
Brugia malayi bone morphogenetic protein type 1 receptor 0.0973 0.0802 0.0813
Trypanosoma brucei polo-like protein kinase 0.0336 0.0094 0.0095
Schistosoma mansoni tyrosine kinase 0.2088 0.2042 0.5028
Giardia lamblia Kinase, CAMK CAMKL 0.0402 0.0167 0.1503
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0375 0.0137 0.0139
Echinococcus granulosus c-Jun N-terminal kinases 0.3006 0.3063 0.3107
Loa Loa (eye worm) AGC/PKN protein kinase 0.1712 0.1624 0.1647
Trypanosoma cruzi casein kinase II, putative 0.0253 0.0001 0.0001
Echinococcus granulosus casein kinase I alpha 0.0642 0.0434 0.044
Brugia malayi Temporarily assigned gene name protein 59 0.0682 0.0479 0.0486
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0128 0.1156
Trypanosoma cruzi cdc2-related kinase 1 0.0465 0.0237 0.0241
Echinococcus multilocularis MAM 0.0377 0.0139 0.0139
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.057 0.0354 0.3386
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0973 0.0802 0.0813
Trichomonas vaginalis CMGC family protein kinase 0.0296 0.0049 0.0439
Leishmania major protein kinase A catalytic subunit isoform 2 0.0754 0.0558 0.0566
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0296 0.0049 0.0049
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.057 0.0354 0.3386
Loa Loa (eye worm) hypothetical protein 0.1484 0.137 0.139
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0682 0.0479 0.0486
Trichomonas vaginalis STE family protein kinase 0.1249 0.1109 1
Schistosoma mansoni protein kinase 0.2542 0.2547 0.627
Loa Loa (eye worm) hypothetical protein 0.0761 0.0566 0.0574
Echinococcus granulosus protein kinase c epsilon type 0.0722 0.0523 0.053
Echinococcus multilocularis G protein coupled receptor kinase 6 0.1471 0.1356 0.1356
Onchocerca volvulus 0.0682 0.0479 0.0652
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.2041 0.1989 0.2018
Loa Loa (eye worm) hypothetical protein 0.0682 0.0479 0.0486
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.1108 0.0952 0.0952
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.1108 0.0952 0.0952
Echinococcus granulosus roundabout 2 0.031 0.0065 0.0066
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1108 0.0952 0.0952
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.057 0.0354 0.0359
Echinococcus multilocularis slit 2 protein 0.0275 0.0026 0.0026
Schistosoma mansoni titin 0.0276 0.0026 0.0065
Trichomonas vaginalis AGC family protein kinase 0.0599 0.0386 0.3482
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0128 0.1156
Loa Loa (eye worm) hypothetical protein 0.0276 0.0026 0.0027
Onchocerca volvulus 0.0377 0.0139 0.0189
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1394 0.127 0.127
Schistosoma mansoni protein kinase 0.0394 0.0158 0.0388
Trichomonas vaginalis CMGC family protein kinase 0.0296 0.0049 0.0439
Entamoeba histolytica protein kinase, putative 0.0296 0.0049 0.0466
Echinococcus multilocularis serine:threonine protein kinase N2 0.1147 0.0996 0.0996
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0269 0.0019 0.002
Echinococcus granulosus tyrosine protein kinase shark 0.0712 0.0512 0.0519
Brugia malayi Casein kinase II, alpha chain 0.0253 0.0001 0.0001
Giardia lamblia Kinase, NEK 0.0293 0.0045 0.0408
Giardia lamblia Kinase, STE STE20 0.0394 0.0158 0.1422
Echinococcus multilocularis cyclin dependent kinase 19 0.1785 0.1705 0.1705
Brugia malayi Protein kinase domain containing protein 0.6853 0.7343 0.7448
Schistosoma mansoni kinase 0.0409 0.0174 0.0429
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0682 0.0479 0.0486
Loa Loa (eye worm) AGC/AKT protein kinase 0.0748 0.0551 0.0559
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0364 0.0125 0.0127
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0441 0.021 0.0213
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.069 0.0487 0.0487
Brugia malayi p70 ribosomal S6 kinase beta 0.0702 0.05 0.0507
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0812 0.0623 0.0632
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0722 0.0523 0.053
Schistosoma mansoni tyrosine kinase 0.0528 0.0307 0.0755
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0458 0.0229 0.0232
Brugia malayi protein unc-22 0.0402 0.0167 0.0169
Brugia malayi Immunoglobulin I-set domain containing protein 0.031 0.0065 0.0066
Echinococcus granulosus cyclin dependent kinase 9 0.0375 0.0137 0.0139
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0682 0.0479 0.1179
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.107 0.091 0.0923
Brugia malayi Protein kinase domain containing protein 0.0312 0.0067 0.0068
Loa Loa (eye worm) CAMK protein kinase 0.0402 0.0167 0.0169
Trichomonas vaginalis AGC family protein kinase 0.0565 0.0348 0.3135
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0361 0.0122 0.0123
Echinococcus multilocularis activated cdc42 kinase 1 0.1731 0.1645 0.1645
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0458 0.0229 0.0229
Brugia malayi SRC-1 0.1108 0.0952 0.0966
Trichomonas vaginalis CAMK family protein kinase 0.0269 0.0019 0.0173
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0367 0.0128 0.013
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0128 0.1156
Trichomonas vaginalis CAMK family protein kinase 0.0336 0.0094 0.0846
Schistosoma mansoni serine/threonine protein kinase 0.0364 0.0125 0.0308
Loa Loa (eye worm) TK protein kinase 0.0707 0.0506 0.0513
Echinococcus multilocularis rac serine:threonine kinase 0.0361 0.0122 0.0122
Echinococcus multilocularis transfer RNA-Thr 0.1731 0.1645 0.1645
Schistosoma mansoni serine/threonine protein kinase 0.1785 0.1705 0.4198
Loa Loa (eye worm) AUR protein kinase 0.0549 0.0331 0.0336
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0367 0.0128 0.013
Trichomonas vaginalis CAMK family protein kinase 0.0336 0.0094 0.0846
Brugia malayi map kinase activated protein kinase protein 2 0.0579 0.0364 0.0369
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0267 0.0016 0.0016
Echinococcus granulosus Immunoglobulin 0.062 0.041 0.0416
Schistosoma mansoni tyrosine kinase 0.0712 0.0512 0.1261
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0682 0.0479 0.0486
Brugia malayi intracellular kinase 0.1191 0.1045 0.106
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0682 0.0479 0.0479
Echinococcus multilocularis calcium activated potassium channel 0.0324 0.008 0.008
Loa Loa (eye worm) TK/FER protein kinase 0.0476 0.0249 0.0252
Loa Loa (eye worm) hypothetical protein 0.0276 0.0026 0.0027
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.031 0.0065 0.016
Echinococcus multilocularis tyrosine protein kinase ABL1 0.2311 0.2291 0.2291
Echinococcus granulosus activated cdc42 kinase 1 0.1731 0.1645 0.1668
Schistosoma mansoni serine/threonine protein kinase 0.107 0.091 0.2241
Entamoeba histolytica PH domain containing protein kinase, putative 0.08 0.0609 0.5829
Onchocerca volvulus 0.0975 0.0804 0.1095
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.057 0.0354 0.0359
Entamoeba histolytica hypothetical protein 0.0255 0.0003 0.0032
Echinococcus granulosus peroxidasin 0.0279 0.003 0.003
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.031 0.0065 0.0065
Onchocerca volvulus 0.0464 0.0236 0.0321
Entamoeba histolytica protein kinase domain containing protein 0.0296 0.0049 0.0469
Schistosoma mansoni tyrosine kinase 0.1108 0.0952 0.2345
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0355 0.0115 0.0117
Schistosoma mansoni serine/threonine protein kinase 0.3006 0.3063 0.7542
Brugia malayi Protein kinase domain containing protein 0.0807 0.0617 0.0626
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0642 0.0434 0.044
Brugia malayi Immunoglobulin I-set domain containing protein 0.0276 0.0026 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0254 0.0002 0.0021
Echinococcus multilocularis dual specificity 0.0296 0.0049 0.0049
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0386 0.0149 0.1348
Brugia malayi Protein kinase domain containing protein 0.0748 0.0551 0.0559
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.1047 0.0885 0.8466
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0128 0.1156
Brugia malayi ribosomal protein S6 kinase alpha 3 0.1021 0.0855 0.0867
Echinococcus granulosus serine:threonine protein kinase mig 15 0.1484 0.137 0.139
Echinococcus granulosus dual specificity 0.0296 0.0049 0.0049
Echinococcus granulosus titin 0.0402 0.0167 0.0169
Brugia malayi ephrin receptor 1 precursor 0.0285 0.0037 0.0038
Echinococcus multilocularis hemicentin 1 0.0276 0.0026 0.0026
Trichomonas vaginalis AGC family protein kinase 0.0267 0.0016 0.0147
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.1047 0.0885 0.0897
Schistosoma mansoni tyrosine kinase 0.0881 0.0699 0.1721
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.1107 0.0952 0.0965
Entamoeba histolytica hypothetical protein 0.0254 0.0002 0.0023
Plasmodium falciparum NIMA related kinase 1 0.0293 0.0045 0.0433
Brugia malayi probable protein kinase 0.1662 0.1568 0.1591
Brugia malayi hypothetical protein 0.0476 0.0249 0.0252
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.233 0.2312 0.2312
Echinococcus granulosus dual specificity 0.0296 0.0049 0.0049
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0754 0.0558 0.0566
Schistosoma mansoni ephrin receptor 0.0287 0.0039 0.0095
Brugia malayi protein C17H12.11 0.0615 0.0404 0.041
Echinococcus multilocularis beta adrenergic receptor kinase 0.0322 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0276 0.0026 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0296 0.0049 0.012
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0276 0.0026 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0842 0.0656 0.1615
Schistosoma mansoni tyrosine kinase 0.1108 0.0952 0.2345
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0402 0.0167 0.1595
Brugia malayi C1-like domain containing protein 0.1107 0.0952 0.0965
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0702 0.05 0.0507
Brugia malayi Protein kinase domain containing protein 0.3947 0.411 0.4169
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.057 0.0354 0.3386
Loa Loa (eye worm) hypothetical protein 0.0975 0.0804 0.0816
Loa Loa (eye worm) TK/EGFR protein kinase 0.1034 0.087 0.0883
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0293 0.0045 0.0433
Brugia malayi Protein kinase domain containing protein 0.0476 0.0249 0.0252
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0465 0.0237 0.0241
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.1155 0.1004 0.1019
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0302 0.0056 0.0056
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.038 0.0142 0.0349
Toxoplasma gondii CMGC kinase, CK2 family 0.0253 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0869 0.0686 0.0696
Echinococcus granulosus lachesin 0.0276 0.0026 0.0027
Giardia lamblia Kinase, STE STE20 0.1249 0.1109 1
Loa Loa (eye worm) hypothetical protein 0.0569 0.0353 0.0358
Brugia malayi Serine/threonine-protein kinase Pim-3 0.2309 0.2288 0.2321
Loa Loa (eye worm) hypothetical protein 0.056 0.0343 0.0348
Brugia malayi Fibronectin type III domain containing protein 0.0655 0.0448 0.0455
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.1108 0.0952 0.0966
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.031 0.0065 0.0065
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.1067 0.0906 0.0919
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0465 0.0237 0.0241
Echinococcus granulosus neuroglian 0.0809 0.062 0.0629
Brugia malayi Peroxidasin 0.0279 0.003 0.003
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1155 0.1004 0.1019
Echinococcus granulosus cyclin dependent kinase 0.0465 0.0237 0.0241
Loa Loa (eye worm) hypothetical protein 0.056 0.0343 0.0348
Echinococcus multilocularis casein kinase I gamma 0.0378 0.014 0.014
Brugia malayi Protein kinase domain containing protein 0.1731 0.1645 0.1668
Toxoplasma gondii AGC kinase 0.0754 0.0558 0.5341
Leishmania major protein kinase, putative 0.0549 0.0331 0.0336
Schistosoma mansoni protein kinase 0.0549 0.0331 0.0814
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.1471 0.1356 0.1375
Brugia malayi Immunoglobulin I-set domain containing protein 0.0276 0.0026 0.0027
Schistosoma mansoni protein kinase 0.0642 0.0434 0.1069
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0276 0.0026 0.0027
Echinococcus granulosus casein kinase I alpha 0.0642 0.0434 0.044
Schistosoma mansoni cell adhesion molecule 0.031 0.0065 0.016
Loa Loa (eye worm) AGC/PKG protein kinase 0.0291 0.0043 0.0044
Entamoeba histolytica protein kinase, putative 0.0394 0.0158 0.1509
Plasmodium vivax calcium-dependent protein kinase, putative 0.057 0.0354 0.3386
Echinococcus granulosus activated cdc42 kinase 1 0.1731 0.1645 0.1668
Plasmodium falciparum casein kinase 2, alpha subunit 0.0253 0.0001 0.0007
Echinococcus granulosus cyclin dependent kinase 5 0.0465 0.0237 0.0241
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.1014 0.0848 0.0848
Echinococcus granulosus protein kinase c iota type 0.0812 0.0623 0.0632
Brugia malayi Protein kinase domain containing protein 0.0465 0.0237 0.0241
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0766 0.0572 0.0572
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.2232 0.2202 0.2234
Loa Loa (eye worm) hypothetical protein 0.0476 0.0249 0.0252
Trichomonas vaginalis STE family protein kinase 0.0394 0.0158 0.1422
Echinococcus granulosus dual specificity mitogen activated protein 0.1249 0.1109 0.1125
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0575 0.036 0.036
Leishmania major protein kinase, putative 0.043 0.0198 0.0201
Trichomonas vaginalis CMGC family protein kinase 0.1191 0.1045 0.942
Echinococcus granulosus serine:threonine protein kinase 0.0312 0.0067 0.0068
Trypanosoma cruzi polo-like protein kinase, putative 0.0336 0.0094 0.0095
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0324 0.008 0.0081
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.1047 0.0885 0.0897
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2309 0.2288 0.2321
Plasmodium falciparum calcium-dependent protein kinase 5 0.057 0.0354 0.3386
Schistosoma mansoni vam6/vps39 related 0.0682 0.0479 0.1179
Trypanosoma cruzi casein kinase, putative 0.0642 0.0434 0.044
Echinococcus multilocularis mitogen activated protein kinase 14 0.9116 0.9859 0.9859
Brugia malayi Cam kinase protein 1 0.057 0.0354 0.0359
Echinococcus granulosus rho-associated protein kinase 1 0.0842 0.0656 0.0665
Trichomonas vaginalis AGC family protein kinase 0.0293 0.0045 0.0408
Brugia malayi hypothetical protein 0.2911 0.2958 0.3
Plasmodium falciparum protein serine/threonine kinase-1 0.1047 0.0885 0.8466
Entamoeba histolytica protein kinase, putative 0.1155 0.1004 0.9613
Loa Loa (eye worm) TK protein kinase 0.1657 0.1562 0.1585
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.2309 0.2288 0.2321
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.2427 0.2419 0.2419
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0253 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.1731 0.1645 0.1668
Trichomonas vaginalis AGC family protein kinase 0.0754 0.0558 0.5031
Echinococcus granulosus casein kinase I gamma 0.0378 0.014 0.0142
Onchocerca volvulus 0.0476 0.0249 0.0339
Schistosoma mansoni serine/threonine protein kinase 0.0565 0.0348 0.0856
Echinococcus granulosus hypothetical protein 0.0869 0.0686 0.0696
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0642 0.0434 0.044
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0001 0.0007
Brugia malayi Egg laying defective protein 4 0.0291 0.0043 0.0044
Echinococcus multilocularis cyclin dependent kinase 5 0.0465 0.0237 0.0237
Schistosoma mansoni serine/threonine protein kinase 0.0367 0.0128 0.0316
Entamoeba histolytica hypothetical protein 0.0255 0.0003 0.0032
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0001 0.0007
Entamoeba histolytica protein kinase , putative 0.0549 0.0331 0.3166
Echinococcus multilocularis protein tyrosine kinase 0.3904 0.4062 0.4062
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.2542 0.2547 0.2547
Schistosoma mansoni serine/threonine protein kinase 0.1648 0.1553 0.3823
Schistosoma mansoni serine/threonine protein kinase 0.0579 0.0364 0.0895
Echinococcus multilocularis TGF beta receptor type 1 0.0899 0.072 0.072
Echinococcus granulosus casein kinase I alpha 0.0642 0.0434 0.044
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0324 0.008 0.008
Schistosoma mansoni atypical protein kinase C 0.0819 0.0631 0.1553
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1468 0.1352 0.1371
Schistosoma mansoni vav2 0.0425 0.0193 0.0475
Loa Loa (eye worm) AGC/PKA protein kinase 0.0754 0.0558 0.0566
Trichomonas vaginalis STE family protein kinase 0.0394 0.0158 0.1422
Trichomonas vaginalis AGC family protein kinase 0.0549 0.0331 0.2983
Trichomonas vaginalis AGC family protein kinase 0.0748 0.0551 0.497
Brugia malayi Protein kinase domain containing protein 0.0476 0.0249 0.0252
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0296 0.0049 0.0466
Echinococcus granulosus STE20 serine:threonine protein kinase 0.069 0.0487 0.0494
Plasmodium falciparum serine/threonine protein kinase, putative 0.0549 0.0331 0.3166
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0754 0.0558 0.0566
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0861 0.0677 0.0677
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0979 0.0809 0.0821
Loa Loa (eye worm) protein kinase domain-containing protein 0.0378 0.014 0.0142
Brugia malayi Immunoglobulin I-set domain containing protein 0.0276 0.0026 0.0027
Giardia lamblia Kinase, CK1 Casein kinase 0.0642 0.0434 0.3915
Trypanosoma brucei Casein kinase II 0.0253 0.0001 0.0001
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0465 0.0237 0.2271
Brugia malayi Protein kinase domain containing protein 0.0807 0.0617 0.0626
Echinococcus multilocularis serine threonine protein kinase 0.061 0.0398 0.0398
Entamoeba histolytica PH domain containing protein kinase, putative 0.08 0.0609 0.5829
Echinococcus granulosus tyrosine kinase 0.0476 0.0249 0.0252
Brugia malayi Immunoglobulin I-set domain containing protein 0.0464 0.0236 0.0239
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1108 0.0952 0.0952
Trichomonas vaginalis CAMK family protein kinase 0.0371 0.0132 0.1193
Echinococcus multilocularis protein kinase shaggy 0.1191 0.1045 0.1045
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0296 0.0049 0.0049
Echinococcus multilocularis tyrosine protein kinase Blk 0.0931 0.0755 0.0755
Trichomonas vaginalis AGC family protein kinase 0.0549 0.0331 0.2983
Loa Loa (eye worm) hypothetical protein 0.0761 0.0566 0.0574
Trypanosoma brucei protein kinase, putative 0.0269 0.0019 0.0019
Trichomonas vaginalis CAMK family protein kinase 0.0415 0.0182 0.1637
Entamoeba histolytica casein kinase, putative 0.0253 0.0001 0.0007
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0565 0.0348 0.0353
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0271 0.0021 0.0021
Echinococcus granulosus serine:threonine protein kinase 3 0.0426 0.0194 0.0197
Echinococcus granulosus NCK adaptor protein 0.0401 0.0166 0.0168
Brugia malayi protein kinase C3,putative 0.0426 0.0194 0.0196
Onchocerca volvulus Tyrosine kinase homolog 0.2939 0.2989 0.4071
Loa Loa (eye worm) hypothetical protein 0.0377 0.0139 0.0141
Onchocerca volvulus 0.0476 0.0249 0.0339
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0489 0.0263 0.0267
Giardia lamblia Kinase, CAMK CAMKL 0.0402 0.0167 0.1503
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0255 0.0003 0.0032
Onchocerca volvulus 0.0664 0.0458 0.0624
Schistosoma mansoni serine/threonine protein kinase 0.0754 0.0558 0.1374
Schistosoma mansoni serine/threonine protein kinase 0.0322 0.0078 0.0191
Brugia malayi serine/threonine kinase 12 0.0549 0.0331 0.0336
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0754 0.0558 0.0566
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0754 0.0558 0.0566
Schistosoma mansoni tyrosine kinase 0.0653 0.0446 0.1099
Brugia malayi cell division control protein 2 homolog 0.0465 0.0237 0.0241
Entamoeba histolytica protein kinase domain containing protein 0.0375 0.0137 0.1315
Trypanosoma brucei aurora B kinase 0.0549 0.0331 0.0336
Leishmania major casein kinase II, putative 0.0253 0.0001 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0465 0.0237 0.0584
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0336 0.0094 0.0095
Entamoeba histolytica hypothetical protein 0.0422 0.0189 0.1805
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1468 0.1352 0.1352
Entamoeba histolytica protein kinase domain containing protein 0.0296 0.0049 0.0466
Schistosoma mansoni tyrosine kinase 0.0629 0.0419 0.1031
Brugia malayi Protein kinase c protein 2 0.0379 0.0142 0.0144
Schistosoma mansoni septate junction protein 0.0276 0.0026 0.0065
Schistosoma mansoni tyrosine kinase 0.0881 0.0699 0.1721
Echinococcus granulosus tyrosine protein kinase Btk29A 0.2427 0.2419 0.2454
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0682 0.0479 0.0486
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0291 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0821 0.0633 0.0642
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0951 0.0778 0.0789
Schistosoma mansoni protein kinase 0.0394 0.0158 0.0388
Loa Loa (eye worm) TK/ROR protein kinase 0.0441 0.021 0.0213
Schistosoma mansoni protein kinase 0.0973 0.0802 0.1975
Echinococcus granulosus MAM 0.0377 0.0139 0.0141
Schistosoma mansoni protein kinase C mu 0.1107 0.0952 0.2343
Schistosoma mansoni titin 0.0402 0.0167 0.0411
Schistosoma mansoni hypothetical protein 0.0682 0.0479 0.1179
Schistosoma mansoni serine/threonine protein kinase 0.0766 0.0572 0.1407
Entamoeba histolytica protein kinase domain containing protein 0.1155 0.1004 0.9613
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0336 0.0094 0.0095
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.057 0.0354 0.0359
Echinococcus granulosus tyrosine protein kinase Fyn 0.1108 0.0952 0.0966
Echinococcus multilocularis growth factor receptor bound protein 2 0.0401 0.0166 0.0166
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0793 0.0602 0.0611
Trichomonas vaginalis CK1 family protein kinase 0.0642 0.0434 0.3915
Echinococcus multilocularis dual specificity protein kinase clk2 0.1047 0.0885 0.0885
Onchocerca volvulus 0.0412 0.0177 0.0242
Onchocerca volvulus 0.0402 0.0167 0.0227
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0366 0.0127 0.0129
Onchocerca volvulus 0.0476 0.0249 0.0339
Echinococcus granulosus TGF-beta receptor type-1 0.0899 0.072 0.073
Giardia lamblia Kinase, AGC PKA 0.0315 0.007 0.0635
Echinococcus multilocularis mitogen activated protein kinase 11 0.9116 0.9859 0.9859
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.1047 0.0885 0.0897
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0309 0.0063 0.0064
Echinococcus granulosus Protein kinase C brain isozyme 0.0766 0.0572 0.058
Loa Loa (eye worm) TK/FAK protein kinase 0.3947 0.411 0.4169
Schistosoma mansoni cell adhesion molecule 0.0742 0.0545 0.1342
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.057 0.0354 0.0359
Echinococcus multilocularis dual specificity mitogen activated protein 0.1249 0.1109 0.1109
Echinococcus multilocularis tyrosine protein kinase shark 0.0712 0.0512 0.0512
Brugia malayi Immunoglobulin I-set domain containing protein 0.0402 0.0167 0.0169
Brugia malayi Protein kinase domain containing protein 0.2243 0.2214 0.2246
Trypanosoma brucei protein kinase, putative 0.043 0.0198 0.0201
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0549 0.0331 0.0336
Brugia malayi EGF-like domain containing protein 0.0275 0.0026 0.0026
Trichomonas vaginalis AGC family protein kinase 0.0549 0.0331 0.2983
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0754 0.0558 0.0558
Trichomonas vaginalis AGC family protein kinase 0.0565 0.0348 0.3135
Entamoeba histolytica protein kinase, putative 0.1155 0.1004 0.9613
Loa Loa (eye worm) hypothetical protein 0.0655 0.0448 0.0455
Schistosoma mansoni serine/threonine kinase 0.045 0.022 0.0542
Echinococcus granulosus twitchin 0.0987 0.0818 0.083
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0565 0.0348 0.0348
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.9116 0.9859 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0821 0.0633 0.0642
Plasmodium falciparum calcium-dependent protein kinase 4 0.057 0.0354 0.3386
Brugia malayi Protein kinase domain containing protein 0.0476 0.0249 0.0252
Loa Loa (eye worm) hypothetical protein 0.0276 0.0026 0.0027
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0001 0.0007
Schistosoma mansoni protein kinase 0.0355 0.0115 0.0283
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0754 0.0558 0.0566
Plasmodium vivax glycogen synthase kinase 3, putative 0.1191 0.1045 1
Trichomonas vaginalis CAMK family protein kinase 0.0336 0.0094 0.0846
Echinococcus multilocularis Immunoglobulin 0.062 0.041 0.041
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0464 0.0236 0.0239
Loa Loa (eye worm) hypothetical protein 0.1325 0.1194 0.1211
Schistosoma mansoni serine/threonine protein kinase 0.0458 0.0229 0.0564
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0128 0.1156
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.0043 0.0107
Plasmodium falciparum protein kinase, putative 0.043 0.0198 0.1897
Loa Loa (eye worm) hypothetical protein 0.4615 0.4853 0.4922
Entamoeba histolytica protein kinase, putative 0.0549 0.0331 0.3166
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0128 0.1156
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0754 0.0558 0.0566
Giardia lamblia Kinase, CMGC CK2 0.0253 0.0001 0.0007
Echinococcus multilocularis Immunoglobulin 0.062 0.041 0.041
Echinococcus granulosus contactin 0.031 0.0065 0.0066
Loa Loa (eye worm) hypothetical protein 0.0367 0.0128 0.013
Entamoeba histolytica protein kinase, putative 0.0571 0.0355 0.3401
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0268 0.0018 0.0018
Echinococcus multilocularis dual specificity 0.0296 0.0049 0.0049
Loa Loa (eye worm) AGC/NDR protein kinase 0.0565 0.0348 0.0353
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.1047 0.0885 0.0897
Schistosoma mansoni serine/threonine protein kinase 0.0367 0.0128 0.0315
Loa Loa (eye worm) TK/INSR protein kinase 0.1359 0.1232 0.1249
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0639 0.0431 0.0437
Brugia malayi Protein kinase domain containing protein 0.0466 0.0238 0.0242
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0402 0.0167 0.1596
Loa Loa (eye worm) hypothetical protein 0.1479 0.1365 0.1384
Schistosoma mansoni ste20-related kinase 0.0369 0.013 0.0321
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.2911 0.2958 0.3
Loa Loa (eye worm) SRC-1 0.1108 0.0952 0.0966
Schistosoma mansoni protein kinase 0.0899 0.072 0.1773
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0549 0.0331 0.3166
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0458 0.0229 0.0232
Schistosoma mansoni serine/threonine protein kinase 0.1047 0.0885 0.2178
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0322 0.0078 0.0079
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0315 0.007 0.007
Brugia malayi SH2 domain containing protein 0.0476 0.0249 0.0252
Brugia malayi casein kinase I 0.0642 0.0434 0.044
Plasmodium vivax unspecified product 0.0253 0.0001 0.0007
Plasmodium falciparum calcium-dependent protein kinase 1 0.057 0.0354 0.3386
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.0029 0.5
Echinococcus granulosus cGMP dependent protein kinase 0.0291 0.0043 0.0044
Brugia malayi Protein kinase domain containing protein 0.0442 0.0211 0.0214
Trichomonas vaginalis AGC family protein kinase 0.0748 0.0551 0.497
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0001 0.0007
Trypanosoma brucei protein kinase, putative 0.1191 0.1045 0.106
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.2309 0.2288 0.2288
Schistosoma mansoni serine/threonine protein kinase 0.0722 0.0523 0.1287
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0128 0.1156
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1394 0.127 0.1288
Brugia malayi Fes/CIP4 homology domain containing protein 0.0817 0.0629 0.0638
Schistosoma mansoni serine/threonine protein kinase 0.0465 0.0237 0.0584
Loa Loa (eye worm) TK/FER protein kinase 0.0476 0.0249 0.0252
Echinococcus granulosus epidermal growth factor receptor 0.1034 0.087 0.0883
Echinococcus granulosus mitogen activated protein kinase 11 0.9116 0.9859 1
Schistosoma mansoni protein kinase 0.037 0.0131 0.0322
Schistosoma mansoni protein kinase 0.1249 0.1109 0.2731
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0754 0.0558 0.5341
Echinococcus multilocularis neuroglian 0.0809 0.062 0.062
Echinococcus granulosus serine:threonine protein kinase 0.0312 0.0067 0.0068
Trichomonas vaginalis STE family protein kinase 0.0394 0.0158 0.1422
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.057 0.0354 0.0354
Entamoeba histolytica protein kinase 2, putative 0.0315 0.007 0.0675
Brugia malayi Variant SH3 domain containing protein 0.0401 0.0166 0.0168
Loa Loa (eye worm) AUR protein kinase 0.0549 0.0331 0.0336
Echinococcus granulosus tyrosine protein kinase Fyn 0.1108 0.0952 0.0966
Echinococcus granulosus dual specificity 0.1155 0.1004 0.1019
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0754 0.0558 0.0566
Brugia malayi Tyrosine-protein kinase abl-1 0.1134 0.0981 0.0995
Echinococcus granulosus raf serine:threonine protein kinase 0.0408 0.0173 0.0176
Echinococcus multilocularis tyrosine kinase 0.0476 0.0249 0.0249
Echinococcus multilocularis expressed conserved protein 0.0291 0.0043 0.0043
Loa Loa (eye worm) TK/FER protein kinase 0.0476 0.0249 0.0252
Echinococcus granulosus tyrosine protein kinase otk 0.0276 0.0026 0.0027
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0367 0.0128 0.013
Echinococcus granulosus tyrosine kinase 0.0931 0.0755 0.0766
Schistosoma mansoni serine/threonine protein kinase 0.1014 0.0848 0.2087
Trichomonas vaginalis AGC family protein kinase 0.0748 0.0551 0.497
Loa Loa (eye worm) hypothetical protein 0.0747 0.0551 0.0559
Entamoeba histolytica casein kinase 1, putative 0.0642 0.0434 0.4156
Schistosoma mansoni protein kinase 0.233 0.2312 0.5692
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0296 0.0049 0.0049
Entamoeba histolytica serine/threonine protein kinase, putative 0.0336 0.0094 0.0899
Schistosoma mansoni protein kinase 0.043 0.0198 0.0488
Echinococcus multilocularis cyclin dependent kinase 9 0.041 0.0176 0.0176
Echinococcus multilocularis 0.0979 0.0809 0.0809
Echinococcus granulosus tyrosine protein kinase Src42A 0.0695 0.0493 0.05
Onchocerca volvulus 0.0761 0.0566 0.0771
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0401 0.0166 0.0409
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.1191 0.1045 0.2572
Entamoeba histolytica protein kinase, putative 0.0707 0.0506 0.4843
Echinococcus granulosus cyclin dependent kinase 1 0.0465 0.0237 0.0241
Loa Loa (eye worm) TK/FER protein kinase 0.0476 0.0249 0.0252
Schistosoma mansoni serine/threonine protein kinase 0.0766 0.0572 0.1407
Echinococcus granulosus mitogen activated protein kinase 14 0.9116 0.9859 1
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0394 0.0158 0.0158
Echinococcus granulosus serine:threonine protein kinase N2 0.1147 0.0996 0.101
Echinococcus multilocularis serine:threonine protein kinase 0.0312 0.0067 0.0067
Schistosoma mansoni nephrin 0.0844 0.0659 0.1621
Echinococcus multilocularis activin receptor type 0.4113 0.4294 0.4294
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0366 0.0127 0.0129
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.0127 0.1218
Echinococcus granulosus fibroblast growth factor receptor 4 0.1468 0.1352 0.1371
Echinococcus multilocularis neuroglian 0.031 0.0065 0.0065
Leishmania major protein kinase, putative 0.1047 0.0885 0.0897
Trypanosoma cruzi casein kinase, putative 0.0642 0.0434 0.044
Echinococcus multilocularis epidermal growth factor receptor 0.0881 0.0699 0.0699
Trichomonas vaginalis CMGC family protein kinase 0.0296 0.0049 0.0439
Schistosoma mansoni tyrosine kinase 0.1468 0.1352 0.3329
Loa Loa (eye worm) hypothetical protein 0.0954 0.0781 0.0792
Echinococcus granulosus growth factor receptor bound protein 2 0.0418 0.0184 0.0187
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.043 0.0198 0.0201
Loa Loa (eye worm) hypothetical protein 0.0615 0.0404 0.041
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0899 0.072 0.072
Brugia malayi RhoGAP domain containing protein 0.038 0.0142 0.0144
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0001 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0269 0.0019 0.0173
Toxoplasma gondii AGC kinase 0.0754 0.0558 0.5341
Echinococcus multilocularis roundabout 2 0.031 0.0065 0.0065
Toxoplasma gondii aurora kinase 0.0549 0.0331 0.3166
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0336 0.0094 0.0095
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.107 0.091 0.091
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0441 0.021 0.021
Brugia malayi P38 map kinase family protein 2 0.9116 0.9859 1
Brugia malayi Protein kinase domain containing protein 0.0565 0.0348 0.0353
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0549 0.0331 0.3166
Schistosoma mansoni protein kinase 0.043 0.0198 0.0488
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0367 0.0128 0.0128
Entamoeba histolytica protein kinase, putative 0.0416 0.0182 0.1741
Schistosoma mansoni serine/threonine protein kinase 0.0671 0.0466 0.1147
Echinococcus granulosus casein kinase I delta 0.0642 0.0434 0.044
Echinococcus granulosus activin receptor type 0.4113 0.4294 0.4356
Echinococcus granulosus tyrosine protein kinase Src42A 0.1108 0.0952 0.0966
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1407 0.1285 0.1285
Echinococcus multilocularis cyclin dependent kinase 1 0.0465 0.0237 0.0237
Echinococcus granulosus serine:threonine protein kinase TAO1 0.2911 0.2958 0.3
Loa Loa (eye worm) hypothetical protein 0.0896 0.0716 0.0727
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.1108 0.0952 0.0966
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2309 0.2288 0.2321
Brugia malayi Protein kinase domain containing protein 0.0793 0.0602 0.0611
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0465 0.0237 0.0241
Echinococcus multilocularis twitchin 0.0367 0.0128 0.0128
Onchocerca volvulus 0.0773 0.058 0.079
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0442 0.0211 0.0214
Schistosoma mansoni serine/threonine protein kinase 0.1712 0.1624 0.3998
Brugia malayi Hr1 repeat family protein 0.1712 0.1624 0.1647
Echinococcus multilocularis ephrin type A receptor 4 A 0.0323 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0377 0.0139 0.0141
Trichomonas vaginalis CAMK family protein kinase 0.0312 0.0067 0.0601
Trypanosoma brucei cdc2-related kinase 3 0.0465 0.0237 0.0241
Brugia malayi Protein kinase domain containing protein 0.0803 0.0613 0.0622
Echinococcus granulosus calcium dependent protein kinase 0.0392 0.0156 0.0158
Brugia malayi Protein kinase domain containing protein 0.1155 0.1004 0.1019
Trypanosoma brucei casein kinase I, isoform 2 0.0642 0.0434 0.044
Echinococcus multilocularis insulin receptor 0.1359 0.1232 0.1232
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0315 0.007 0.0675
Schistosoma mansoni serine/threonine protein kinase 0.107 0.091 0.2241
Trichomonas vaginalis CAMK family protein kinase 0.0336 0.0094 0.0846
Schistosoma mansoni ephrin receptor 0.0323 0.0079 0.0194
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0465 0.0237 0.0241
Echinococcus granulosus neuroglian 0.031 0.0065 0.0066
Onchocerca volvulus Slit protein homolog 0.0275 0.0026 0.0035
Echinococcus granulosus tyrosine protein kinase HCK 0.0707 0.0506 0.0513
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.3006 0.3063 0.3107
Echinococcus granulosus cGMP dependent protein kinase 1 0.0291 0.0043 0.0044
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0128 0.1156
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.1249 0.1109 0.1125
Loa Loa (eye worm) CAMK/PKD protein kinase 0.1107 0.0952 0.0965
Trypanosoma cruzi polo-like protein kinase, putative 0.0336 0.0094 0.0095
Schistosoma mansoni growth factor receptor-bound protein 0.0418 0.0184 0.0454
Loa Loa (eye worm) hypothetical protein 0.0328 0.0084 0.0085
Toxoplasma gondii AGC kinase 0.0702 0.05 0.4788
Echinococcus multilocularis tyrosine protein kinase Fgr 0.1108 0.0952 0.0952
Brugia malayi Protein kinase domain containing protein 0.1359 0.1232 0.1249
Plasmodium vivax serine/threonine kinase-1, putative 0.1047 0.0885 0.8466
Loa Loa (eye worm) hypothetical protein 0.0279 0.003 0.003
Echinococcus multilocularis dual specificity testis specific protein kinase 0.043 0.0198 0.0198
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0276 0.0026 0.0026
Trichomonas vaginalis AGC family protein kinase 0.0748 0.0551 0.497
Loa Loa (eye worm) TK protein kinase 0.0588 0.0374 0.038
Loa Loa (eye worm) hypothetical protein 0.0276 0.0026 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0754 0.0558 0.1374
Loa Loa (eye worm) hypothetical protein 0.0747 0.0551 0.0559
Entamoeba histolytica protein kinase domain containing protein 0.043 0.0198 0.1897
Echinococcus granulosus c src tyrosine kinase 0.0653 0.0446 0.0453
Echinococcus granulosus cGMP dependent protein kinase 1 0.0291 0.0043 0.0044
Onchocerca volvulus 0.0338 0.0096 0.0131
Brugia malayi Protein kinase domain containing protein 0.2309 0.2288 0.2321
Loa Loa (eye worm) thyroid receptor interactor 0.0817 0.0629 0.0638
Echinococcus granulosus serine threonine protein kinase nrc 0.0315 0.007 0.0071
Brugia malayi Protein kinase domain 0.0394 0.0158 0.016
Loa Loa (eye worm) hypothetical protein 0.0773 0.058 0.0588
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.057 0.0354 0.3386
Trichomonas vaginalis CMGC family protein kinase 0.0253 0.0001 0.0007
Echinococcus multilocularis protein kinase c epsilon type 0.0722 0.0523 0.0523
Entamoeba histolytica PH domain containing protein kinase, putative 0.0361 0.0122 0.1163
Trypanosoma cruzi cdc2-related kinase 3 0.0465 0.0237 0.0241
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0268 0.0018 0.0019
Trichomonas vaginalis STE family protein kinase 0.0394 0.0158 0.1422
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0394 0.0158 0.016
Trypanosoma brucei rac serine-threonine kinase, putative 0.0748 0.0551 0.0559
Giardia lamblia Kinase, CMGC CDK 0.0465 0.0237 0.2139
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.9116 0.9859 1
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0465 0.0237 0.0241
Echinococcus multilocularis protein kinase c iota type 0.0812 0.0623 0.0623
Echinococcus granulosus slit 2 protein 0.0275 0.0026 0.0026
Schistosoma mansoni serine/threonine protein kinase 0.0375 0.0137 0.0338
Schistosoma mansoni tyrosine kinase 0.0443 0.0213 0.0524
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0881 0.0699 0.0709
Brugia malayi cyclin-dependent kinase 7 homolog 0.0641 0.0433 0.0439
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0128 0.1156
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0812 0.0623 0.0623
Echinococcus granulosus NDR protein kinase 0.0565 0.0348 0.0353
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0269 0.0019 0.0019
Echinococcus granulosus calcium activated potassium channel 0.0324 0.008 0.0081
Plasmodium falciparum protein kinase 5 0.0465 0.0237 0.2271
Echinococcus granulosus ephrin type A receptor 4 A 0.0323 0.0079 0.008
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0861 0.0677 0.0687
Brugia malayi Immunoglobulin I-set domain containing protein 0.0276 0.0026 0.0027
Echinococcus granulosus defective proboscis extension response 0.062 0.041 0.0416
Echinococcus granulosus tyrosine protein kinase Fyn 0.1108 0.0952 0.0966
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0394 0.0158 0.016
Trichomonas vaginalis CMGC family protein kinase 0.0465 0.0237 0.2139
Loa Loa (eye worm) hypothetical protein 0.0401 0.0166 0.0168
Echinococcus multilocularis serine:threonine protein kinase 38 0.0565 0.0348 0.0348
Loa Loa (eye worm) hypothetical protein 0.0655 0.0448 0.0455
Echinococcus multilocularis c src tyrosine kinase 0.0653 0.0446 0.0446
Brugia malayi hypothetical protein 0.0615 0.0404 0.041
Giardia lamblia Kinase, NEK 0.0293 0.0045 0.0408
Brugia malayi Doublecortin family protein 0.0309 0.0063 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0367 0.0128 0.0316
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1407 0.1285 0.1303
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0394 0.0158 0.016
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0754 0.0558 0.0566
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.233 0.2312 0.2345
Loa Loa (eye worm) hypothetical protein 0.0275 0.0026 0.0026
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0276 0.0026 0.0065
Giardia lamblia Aurora kinase 0.0549 0.0331 0.2983
Echinococcus granulosus protein tyrosine kinase 0.3904 0.4062 0.412
Schistosoma mansoni cell adhesion molecule 0.0276 0.0026 0.0065
Trypanosoma cruzi casein kinase, putative 0.0642 0.0434 0.044
Entamoeba histolytica protein kinase domain containing protein 0.1191 0.1045 1
Echinococcus multilocularis tyrosine protein kinase Srms 0.0931 0.0755 0.0755
Loa Loa (eye worm) AGC/PKA protein kinase 0.0754 0.0558 0.0566
Entamoeba histolytica protein kinase, putative 0.0748 0.0551 0.5276
Echinococcus granulosus protein kinase shaggy 0.1191 0.1045 0.106
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.031 0.0065 0.0066
Plasmodium vivax protein kinase, putative 0.0269 0.0019 0.0178
Onchocerca volvulus 0.0642 0.0434 0.0591
Loa Loa (eye worm) TK/FER protein kinase 0.0476 0.0249 0.0252
Trypanosoma brucei cdc2-related kinase 1 0.0465 0.0237 0.0241
Loa Loa (eye worm) hypothetical protein 0.0512 0.0289 0.0293
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0315 0.007 0.0071
Schistosoma mansoni serine/threonine protein kinase 0.0367 0.0128 0.0316
Echinococcus granulosus casein kinase i 0.0642 0.0434 0.044
Trichomonas vaginalis STE family protein kinase 0.037 0.0131 0.118
Brugia malayi Protein kinase domain containing protein 0.0378 0.014 0.0142
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.1155 0.1004 0.1019
Echinococcus granulosus epidermal growth factor receptor 0.0881 0.0699 0.0709
Loa Loa (eye worm) hypothetical protein 0.0276 0.0026 0.0027
Echinococcus multilocularis 0.0869 0.0686 0.0686
Schistosoma mansoni serine/threonine protein kinase 0.0549 0.0331 0.0814
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.1249 0.1109 0.1125
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0401 0.0166 0.0168
Echinococcus multilocularis casein kinase i 0.0642 0.0434 0.0434
Echinococcus multilocularis tyrosine protein kinase Src64B 0.1108 0.0952 0.0952
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.1191 0.1045 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0324 0.008 0.0109
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0707 0.0506 0.0514
Schistosoma mansoni tyrosine kinase 0.0653 0.0446 0.1099
Entamoeba histolytica protein kinase, putative 0.057 0.0354 0.3386
Loa Loa (eye worm) hypothetical protein 0.0569 0.0353 0.0358
Echinococcus multilocularis casein kinase ii subunit alpha 0.0253 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0312 0.0067 0.0068
Brugia malayi Immunoglobulin I-set domain containing protein 0.0655 0.0448 0.0455
Schistosoma mansoni tyrosine kinase 0.0821 0.0633 0.1559
Schistosoma mansoni tyrosine kinase 0.1359 0.1232 0.3032
Echinococcus granulosus aurora kinase A 0.0549 0.0331 0.0336
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1785 0.1705 0.1729
Schistosoma mansoni protein kinase 0.0979 0.0809 0.1992
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0754 0.0558 0.0558
Echinococcus multilocularis serine:threonine protein kinase 3 0.0426 0.0194 0.0194
Brugia malayi Protein kinase domain containing protein 0.1785 0.1705 0.1729
Echinococcus multilocularis roundabout 2 0.031 0.0065 0.0065
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.043 0.0198 0.0201
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0291 0.0043 0.0043
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0401 0.0166 0.0168
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0291 0.0043 0.0414
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.2911 0.2958 0.2958
Schistosoma mansoni serine/threonine protein kinase 0.0565 0.0348 0.0856
Entamoeba histolytica cell division protein kinase 2, putative 0.05 0.0276 0.2639
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0642 0.0434 0.044
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0276 0.0026 0.0027
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0296 0.0049 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.1155 0.1004 0.2473
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0415 0.0182 0.0184
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0754 0.0558 0.0558
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0367 0.0128 0.013
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2243 0.2214 0.2246
Echinococcus multilocularis casein kinase I delta 0.0642 0.0434 0.0434
Schistosoma mansoni serine/threonine protein kinase 0.0324 0.008 0.0198
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0367 0.0128 0.013
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0579 0.0364 0.0369
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.043 0.0198 0.1897
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0549 0.0331 0.3166
Echinococcus granulosus tyrosine protein kinase ABL1 0.2311 0.2291 0.2323
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.057 0.0354 0.3386
Brugia malayi Protein kinase domain containing protein 0.0324 0.008 0.0081
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0579 0.0364 0.0369
Brugia malayi Variant SH3 domain containing protein 0.0271 0.0021 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.1407 0.1285 0.3163
Schistosoma mansoni protein kinase 0.2542 0.2547 0.627
Loa Loa (eye worm) TK/FER protein kinase 0.0476 0.0249 0.0252
Schistosoma mansoni growth factor receptor-bound protein 0.0401 0.0166 0.0409
Schistosoma mansoni serine/threonine protein kinase 0.057 0.0354 0.0871
Brugia malayi Variant SH3 domain containing protein 0.0401 0.0166 0.0168
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.057 0.0354 0.0359
Echinococcus granulosus glycogen synthase kinase 3 beta 0.1191 0.1045 0.106
Schistosoma mansoni serine/threonine protein kinase 0.2309 0.2288 0.5633
Brugia malayi Protein kinase domain containing protein 0.0338 0.0096 0.0097
Loa Loa (eye worm) gastrulation defective protein 1 0.1607 0.1507 0.1528
Loa Loa (eye worm) hypothetical protein 0.0807 0.0617 0.0626
Trichomonas vaginalis CAMK family protein kinase 0.057 0.0354 0.319
Toxoplasma gondii hypothetical protein 0.0747 0.0551 0.5271
Echinococcus granulosus protein kinase 0.0979 0.0809 0.0821
Echinococcus multilocularis mitogen activated protein kinase 14 0.9116 0.9859 0.9859
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0606 0.0394 0.04
Echinococcus granulosus serine/threonine protein kinase 0.0361 0.0122 0.0123
Schistosoma mansoni serine/threonine-protein kinase 0.0361 0.0122 0.0299
Schistosoma mansoni tyrosine kinase 0.1034 0.087 0.2143
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.038 0.0142 0.0144
Brugia malayi Protein kinase domain containing protein 0.5245 0.5554 0.5633
Loa Loa (eye worm) hypothetical protein 0.031 0.0065 0.0066
Echinococcus multilocularis titin 0.0402 0.0167 0.0167
Plasmodium falciparum glycogen synthase kinase 3 0.1191 0.1045 1
Brugia malayi Protein kinase domain containing protein 0.0565 0.0348 0.0353
Echinococcus granulosus titin 0.0402 0.0167 0.0169
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.1971 0.1913 0.194
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1614 0.1515 0.1537
Echinococcus granulosus dual specificity 0.0296 0.0049 0.0049
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.1047 0.0885 0.0897
Echinococcus multilocularis cyclin dependent kinase 0.0465 0.0237 0.0237
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0315 0.007 0.0071
Echinococcus multilocularis casein kinase I alpha 0.0642 0.0434 0.0434
Loa Loa (eye worm) hypothetical protein 0.0761 0.0566 0.0574
Entamoeba histolytica protein kinase domain containing protein 0.0549 0.0331 0.3166
Loa Loa (eye worm) TK/ABL protein kinase 0.2311 0.2291 0.2323
Entamoeba histolytica protein kinase, putative 0.037 0.0131 0.1253
Brugia malayi Protein kinase domain containing protein 0.233 0.2312 0.2345
Leishmania major protein kinase, putative 0.1047 0.0885 0.0897
Echinococcus multilocularis mitogen activated protein kinase 11 0.9116 0.9859 0.9859
Echinococcus multilocularis serine:threonine protein kinase N2 0.1712 0.1624 0.1624
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0441 0.021 0.0213
Brugia malayi Variant SH3 domain containing protein 0.038 0.0142 0.0144
Echinococcus multilocularis tyrosine protein kinase otk 0.0276 0.0026 0.0026
Trichomonas vaginalis CMGC family protein kinase 0.1047 0.0885 0.7975
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.1971 0.1913 0.194
Trichomonas vaginalis CAMK family protein kinase 0.0367 0.0128 0.1156
Echinococcus multilocularis tumor protein p63 0.0408 0.0174 0.0174
Onchocerca volvulus 0.0356 0.0115 0.0157
Entamoeba histolytica protein kinase domain containing protein 0.0253 0.0001 0.0007
Echinococcus multilocularis NCK adaptor protein 0.0418 0.0184 0.0184
Echinococcus granulosus casein kinase I delta 0.0642 0.0434 0.044
Echinococcus multilocularis tyrosine protein kinase HCK 0.0707 0.0506 0.0506
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0366 0.0127 0.0127
Schistosoma mansoni hypothetical protein 0.0377 0.0139 0.0342
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.057 0.0354 0.0359
Entamoeba histolytica protein kinase, putative 0.0255 0.0003 0.0032
Brugia malayi protein kinase C II. 0.0722 0.0523 0.053
Echinococcus granulosus tyrosine protein kinase Lyn 0.1286 0.115 0.1167
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.5617 0.5968 0.6053
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0394 0.0158 0.0158
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1471 0.1356 0.1375
Schistosoma mansoni serine/threonine protein kinase 0.0606 0.0394 0.0971
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0931 0.0755 0.0755
Leishmania major casein kinase, putative 0.0642 0.0434 0.044

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 5.6234 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 10 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 89.1251 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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