Detailed information for compound 1429730

Basic information

Technical information
  • TDR Targets ID: 1429730
  • Name: 3-(1,3-benzodioxol-5-yl)-1-[5-hydroxy-3-methy l-5-(trifluoromethyl)-4H-pyrazol-1-yl]propan- 1-one
  • MW: 344.286 | Formula: C15H15F3N2O4
  • H donors: 1 H acceptors: 2 LogP: 2.18 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC1=NN(C(C1)(O)C(F)(F)F)C(=O)CCc1ccc2c(c1)OCO2
  • InChi: 1S/C15H15F3N2O4/c1-9-7-14(22,15(16,17)18)20(19-9)13(21)5-3-10-2-4-11-12(6-10)24-8-23-11/h2,4,6,22H,3,5,7-8H2,1H3
  • InChiKey: KAARXXHMFMEOLE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • MLS000709012
  • SMR000289779
  • STK191829
  • BAS 08949925

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax protein kinase Crk2 0.0047 0.0089 0.3165
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.005
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0178 0.0455 0.1706
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.002 0.0295
Loa Loa (eye worm) AUR protein kinase 0.0115 0.0278 0.1042
Loa Loa (eye worm) AUR protein kinase 0.0115 0.0278 0.1042
Echinococcus multilocularis cyclin dependent kinase 1 0.0047 0.0089 0.0089
Schistosoma mansoni titin 0.0017 0.0006 0.0006
Brugia malayi Patched family protein 0.0019 0.0012 0.0043
Echinococcus granulosus receptor type guanylyl cyclase 0.0015 0.0001 0.0001
Entamoeba histolytica acyl-CoA synthetase, putative 0.0103 0.0245 0.142
Echinococcus granulosus tyrosine protein kinase 0.0015 0.0001 0.0001
Brugia malayi Receptor family ligand binding region containing protein 0.0015 0.0001 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0139 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Plasmodium vivax SET domain protein, putative 0.0064 0.0137 0.4908
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0115 0.0278 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0073 0.0161 0.0445
Schistosoma mansoni steroid hormone receptor ad4bp 0.0033 0.0051 0.0051
Mycobacterium tuberculosis Conserved hypothetical protein 0.0044 0.0082 0.0227
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0103 0.0245 0.0551
Onchocerca volvulus 0.0019 0.0012 0.0077
Schistosoma mansoni tyrosine kinase 0.0498 0.1347 0.1347
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0059 0.0123 0.0123
Trypanosoma brucei acetyl-CoA synthetase, putative 0.003 0.0042 0.0648
Entamoeba histolytica protein kinase domain containing protein 0.0019 0.001 0.0056
Echinococcus granulosus cyclin B 0.0017 0.0007 0.0007
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0015 0.0001 0.0005
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0015 0.0001 0.0006
Echinococcus multilocularis rac serine:threonine kinase 0.0027 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0033 0.0052 0.0194
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.0001 0.0005
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.003 0.0042 0.0116
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0022 0.0084
Schistosoma mansoni tyrosine kinase 0.003 0.0043 0.0043
Schistosoma mansoni thyroid hormone receptor 0.0033 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.003 0.0042 0.0159
Loa Loa (eye worm) hypothetical protein 0.0025 0.0027 0.0103
Schistosoma mansoni hypothetical protein 0.0015 0.0001 0.0001
Echinococcus multilocularis casein kinase ii subunit alpha 0.007 0.0154 0.0154
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0015 0.0001 0.0006
Trypanosoma cruzi cyclin, putative 0.0017 0.0007 0.0093
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Giardia lamblia Kinase, AGC PKA 0.0025 0.0028 0.0411
Schistosoma mansoni aldehyde dehydrogenase 0.0194 0.05 0.05
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0001 0.0003
Entamoeba histolytica tyrosine kinase, putative 0.0015 0.0001 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0247 0.0646 0.3754
Toxoplasma gondii patched family protein 0.0019 0.0012 0.0172
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0015 0.0001 0.0008
Schistosoma mansoni tyrosine kinase 0.0709 0.1934 0.1934
Loa Loa (eye worm) hypothetical protein 0.0039 0.0067 0.0252
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.003 0.0042 0.0042
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Brugia malayi Trypsin family protein 0.0025 0.0027 0.0103
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0016 0.0002 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Echinococcus multilocularis titin 0.0018 0.0008 0.0008
Entamoeba histolytica tyrosin kinase, putative 0.0015 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.002 0.029
Brugia malayi Patched family protein 0.0019 0.0012 0.0043
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0103 0.0245 0.0551
Trichomonas vaginalis CAMK family protein kinase 0.0015 0.0001 0.0006
Brugia malayi hypothetical protein 0.0019 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0971 0.2666 1
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0033 0.0051 0.019
Onchocerca volvulus Bile acid receptor homolog 0.0033 0.0051 0.0373
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0001 0.0001
Entamoeba histolytica cell division protein kinase 2, putative 0.0047 0.0089 0.0513
Echinococcus multilocularis protein kinase 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0024
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.0001 0.0005
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0013 0.0013
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Plasmodium falciparum lipid/sterol:H+ symporter 0.0019 0.0012 0.0383
Giardia lamblia Kinase, CMGC CDK 0.0047 0.0089 0.1353
Brugia malayi AMP-binding enzyme family protein 0.003 0.0042 0.0159
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0103 0.0245 0.0643
Echinococcus granulosus beta-adrenergic receptor kinase 0.0025 0.0027 0.0027
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0016 0.0002 0.0004
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0179 0.0458 0.0458
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.0051 0.019
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0059 0.0123 0.0123
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Toxoplasma gondii patched family protein 0.0019 0.0012 0.0172
Trypanosoma cruzi protein kinase, putative 0.0015 0.0001 0.0008
Echinococcus multilocularis tyrosine kinase 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0037 0.0211
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0001 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0042 0.0098
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.002 0.029
Loa Loa (eye worm) hypothetical protein 0.0051 0.01 0.0377
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.003 0.0042 0.0098
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Echinococcus granulosus roundabout 2 0.0023 0.0022 0.0022
Trichomonas vaginalis CMGC family protein kinase 0.007 0.0154 0.0896
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0015 0 0.0002
Schistosoma mansoni tyrosine kinase 0.0262 0.069 0.069
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0037 0.0211
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0005
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Echinococcus granulosus tyrosine protein kinase csk 0.0015 0.0001 0.0001
Echinococcus granulosus tyrosine kinase 0.0052 0.0102 0.0102
Trichomonas vaginalis antibiotic synthetase, putative 0.003 0.0042 0.0245
Leishmania major acetyl-CoA synthetase, putative 0.003 0.0042 0.0644
Entamoeba histolytica hypothetical protein 0.002 0.0013 0.0075
Schistosoma mansoni tyrosine kinase 0.0451 0.1214 0.1214
Entamoeba histolytica serine/threonine kinase, putative 0.0015 0.0001 0.0006
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0025 0.0028 0.0974
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0013 0.0013
Brugia malayi ecdysteroid receptor 0.0033 0.0051 0.019
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Leishmania major cytochrome p450-like protein 0.0017 0.0006 0.008
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.0051 0.019
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Onchocerca volvulus 0.0023 0.0022 0.016
Loa Loa (eye worm) AGC/PKN protein kinase 0.0015 0 0.0002
Onchocerca volvulus 0.0023 0.0022 0.016
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0139 0.0523
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0084
Schistosoma mansoni protein kinase 0.0015 0.0001 0.0001
Brugia malayi Tyrosine-protein kinase PR2 0.0015 0.0001 0.0005
Echinococcus granulosus axis inhibition protein axin 0.002 0.0013 0.0013
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0033 0.0052 0.0052
Brugia malayi Patched family protein 0.0019 0.0012 0.0043
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0033 0.0051 0.019
Trichomonas vaginalis cyclin B, putative 0.0017 0.0007 0.0038
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0015 0.0001 0.0001
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0015 0.0001 0.0001
Brugia malayi Patched family protein 0.0019 0.0012 0.0043
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0013 0.0013
Echinococcus multilocularis expressed conserved protein 0.0295 0.0782 0.0782
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0077 0.0172 0.0646
Loa Loa (eye worm) pigment dispersing factor receptor c 0.021 0.0545 0.2043
Brugia malayi hypothetical protein 0.002 0.0013 0.005
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0007 0.0007
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0051 0.0051
Trypanosoma brucei cytochrome P450, putative 0.0017 0.0006 0.0085
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Echinococcus granulosus Niemann Pick C1 protein 0.0449 0.1211 0.1211
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0002 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Schistosoma mansoni hypothetical protein 0.0041 0.0073 0.0073
Entamoeba histolytica protein kinase, putative 0.0044 0.0081 0.0469
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0022 0.0084
Onchocerca volvulus 0.0064 0.0137 0.1025
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0015 0.0001 0.0001
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0015 0.0001 0.0006
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0059 0.0123 0.0123
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0047 0.0089 0.1359
Trypanosoma brucei unspecified product 0.0022 0.002 0.0295
Leishmania major cyclin 0.0017 0.0007 0.0093
Echinococcus multilocularis Niemann Pick C1 protein 0.0449 0.1211 0.1211
Echinococcus granulosus tyrosine protein kinase pr2 0.0015 0.0001 0.0001
Loa Loa (eye worm) patched family protein 0.0019 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0033 0.0051 0.019
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0071 0.0409
Brugia malayi Immunoglobulin I-set domain containing protein 0.0363 0.0971 0.3642
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.002 0.0014 0.0014
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0001 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0037 0.0211
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0137 0.0137
Schistosoma mansoni protein kinase 0.0015 0.0001 0.0001
Plasmodium vivax multidomain scavenger receptor, putative 0.0061 0.0129 0.4639
Loa Loa (eye worm) hypothetical protein 0.0054 0.0108 0.0404
Loa Loa (eye worm) hypothetical protein 0.0025 0.0027 0.0103
Echinococcus granulosus transmembrane protease serine 3 0.0025 0.0027 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0015 0 0.0002
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0059 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0007
Echinococcus granulosus dna polymerase eta 0.0051 0.01 0.01
Echinococcus multilocularis cyclins 0.0017 0.0007 0.0007
Onchocerca volvulus 0.0103 0.0245 0.1842
Schistosoma mansoni axis inhibition protein axin 0.002 0.0013 0.0013
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Schistosoma mansoni hypothetical protein 0.0158 0.0398 0.0398
Echinococcus granulosus tar DNA binding protein 0.0065 0.0139 0.0139
Brugia malayi nuclear hormone receptor 0.0016 0.0002 0.0007
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0067 0.0144 0.0144
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0041 0.0071 0.0071
Loa Loa (eye worm) AMP-binding enzyme family protein 0.003 0.0042 0.0159
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0077 0.0172 0.0646
Echinococcus granulosus raf serine:threonine protein kinase 0.0015 0.0001 0.0001
Entamoeba histolytica receptor protein kinase, putative 0.0015 0.0001 0.0006
Brugia malayi Cyclin, N-terminal domain containing protein 0.0017 0.0007 0.0026
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0067 0.0144 0.0144
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Loa Loa (eye worm) CXXC zinc finger family protein 0.0124 0.0304 0.1139
Echinococcus granulosus peroxidasin 0.0017 0.0006 0.0006
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0194 0.05 0.7736
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Echinococcus multilocularis cyclins 0.0017 0.0007 0.0007
Onchocerca volvulus 0.0017 0.0006 0.0032
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.0632 0.172 1
Toxoplasma gondii patched family protein 0.0019 0.0012 0.0172
Loa Loa (eye worm) TK protein kinase 0.0015 0.0001 0.0005
Brugia malayi TAR-binding protein 0.0065 0.0139 0.0523
Brugia malayi photoreceptor-specific nuclear receptor 0.0033 0.0051 0.019
Brugia malayi Patched family protein 0.0019 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Trichomonas vaginalis STE family protein kinase 0.0015 0.0001 0.0006
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0044 0.0082 0.1267
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0037 0.0211
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0071 0.0071
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Schistosoma mansoni loxhd1 0.0061 0.0129 0.0129
Brugia malayi Protein kinase domain containing protein 0.0023 0.0022 0.0084
Leishmania major 4-coumarate:coa ligase-like protein 0.0103 0.0245 0.378
Entamoeba histolytica casein kinase, putative 0.007 0.0154 0.0896
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0089 0.0513
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0179 0.0458 0.0458
Brugia malayi hypothetical protein 0.0016 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.021 0.0545 0.2043
Loa Loa (eye worm) TK/ALK protein kinase 0.0015 0.0001 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0137 0.0137
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.003 0.0042 0.0648
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0001 0.0006
Entamoeba histolytica protein kinase, putative 0.0037 0.0062 0.0359
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0033 0.0051 0.019
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Echinococcus multilocularis ephrin type A receptor 4 A 0.0082 0.0186 0.0186
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0015 0.0001 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0037 0.0211
Plasmodium falciparum tyrosine kinase-like protein 0.0015 0.0001 0.0018
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0071 0.0409
Onchocerca volvulus 0.003 0.0042 0.0311
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.002 0.0112
Loa Loa (eye worm) hypothetical protein 0.0061 0.0129 0.0485
Leishmania major 4-coumarate:coa ligase-like protein 0.0103 0.0245 0.378
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0033 0.0051 0.0051
Echinococcus granulosus fibroblast growth factor receptor 4 0.0015 0.0001 0.0001
Onchocerca volvulus 0.0023 0.0022 0.016
Onchocerca volvulus 0.0015 0.0001 0.000000054205
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.003 0.0042 0.0116
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0027 0.0027
Trichomonas vaginalis cyclins, putative 0.0017 0.0007 0.0038
Schistosoma mansoni tsg101-related 0.0063 0.0134 0.0134
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0001 0.0001
Entamoeba histolytica tyrosine kinase, putative 0.0015 0.0001 0.0006
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0033 0.0051 0.0051
Brugia malayi Trypsin family protein 0.0025 0.0027 0.0103
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0051 0.0051
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0015 0.0001 0.0005
Entamoeba histolytica tyrosine kinase, putative 0.0015 0.0001 0.0006
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0137 0.0137
Schistosoma mansoni hypothetical protein 0.1764 0.4876 0.4876
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0015 0.0001 0.0001
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0027 0.0027
Echinococcus granulosus insulin receptor 0.0451 0.1214 0.1214
Trypanosoma brucei cdc2-related kinase 1 0.0047 0.0089 0.1363
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0033 0.0051 0.019
Echinococcus granulosus cyclins 0.0017 0.0007 0.0007
Echinococcus granulosus tyrosine protein kinase csk 0.0015 0.0001 0.0001
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0015 0.0001 0.0006
Echinococcus granulosus flap endonuclease 1 0.0028 0.0037 0.0037
Brugia malayi hypothetical protein 0.002 0.0013 0.005
Trypanosoma brucei hypothetical protein, conserved 0.0218 0.0567 0.877
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0019 0.0019
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0005
Entamoeba histolytica hypothetical protein 0.0015 0.0001 0.0006
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0016 0.0002 0.0007
Entamoeba histolytica protein kinase domain containing protein 0.007 0.0154 0.0896
Giardia lamblia Kinase, CMGC CK2 0.007 0.0154 0.2375
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0024 0.0026 0.0393
Brugia malayi nuclear receptor NHR-88 0.0016 0.0002 0.0007
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0027 0.0027
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0047 0.0089 0.0332
Loa Loa (eye worm) cyclin domain-containing protein 0.0017 0.0007 0.0026
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0006 0.0024
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.0002 0.0002
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0027 0.0027
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0015 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Echinococcus granulosus tyrosine protein kinase Src42A 0.0036 0.0059 0.0059
Mycobacterium leprae N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase MshB (GlcNAc-Ins deacetylase) 0.0044 0.0082 0.0109
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0015 0.0001 0.0006
Brugia malayi Protein kinase domain containing protein 0.0178 0.0455 0.1706
Echinococcus multilocularis activated cdc42 kinase 1 0.0015 0.0001 0.0001
Echinococcus granulosus axis inhibition protein axin 0.002 0.0013 0.0013
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.002 0.0295
Echinococcus multilocularis cyclin dependent kinase 1 0.0047 0.0089 0.0089
Brugia malayi protein unc-22 0.0018 0.0008 0.0031
Schistosoma mansoni protein kinase 0.002 0.0015 0.0015
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0023 0.0022 0.0022
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.003 0.0042 0.0116
Echinococcus multilocularis dnaJ subfamily B 0.1764 0.4876 0.4876
Echinococcus granulosus dnaJ subfamily B 0.1764 0.4876 0.4876
Trypanosoma cruzi Protein kinase B 0.0027 0.0033 0.0505
Trypanosoma brucei Pseudokinase, putative 0.0015 0.0001 0.0012
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0498 0.1347 0.1347
Loa Loa (eye worm) TK protein kinase 0.0015 0.0001 0.0005
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0015 0 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0247 0.0646 0.3754
Entamoeba histolytica serine/threonine kinase, putative 0.0015 0.0001 0.0006
Schistosoma mansoni regulator of G protein signaling 0.002 0.0013 0.0013
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0001 0.0001
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0044 0.0082 0.1262
Entamoeba histolytica dual specificity protein phosphatase, putative 0.0632 0.172 1
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0022 0.0084
Loa Loa (eye worm) TK protein kinase 0.0044 0.0081 0.0304
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.003 0.0043 0.0043
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0073 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0247 0.0646 0.3754
Entamoeba histolytica tyrosine kinase, putative 0.0015 0.0001 0.0006
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0319 0.0848 0.0848
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0037 0.0211
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Schistosoma mansoni protein kinase 0.0015 0.0001 0.0001
Onchocerca volvulus 0.0061 0.0129 0.0969
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0033 0.0051 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0037 0.0211
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Echinococcus multilocularis nervana 2 0.002 0.0014 0.0014
Onchocerca volvulus 0.0019 0.0012 0.0077
Schistosoma mansoni protein kinase 0.0015 0.0001 0.0001
Brugia malayi nuclear hormone receptor family member nhr-6 0.0016 0.0002 0.0007
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0115 0.0278 0.1614
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.002 0.0015 0.0217
Mycobacterium ulcerans acyl-CoA synthetase 0.0103 0.0245 0.0643
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0033 0.005 0.005
Echinococcus granulosus Niemann Pick C1 protein 0.0314 0.0835 0.0835
Echinococcus granulosus retinal guanylyl cyclase 2 0.0015 0.0001 0.0001
Schistosoma mansoni cell adhesion molecule 0.0017 0.0006 0.0006
Trichomonas vaginalis cyclin B, putative 0.0017 0.0007 0.0038
Mycobacterium ulcerans acyl-CoA synthetase 0.0103 0.0245 0.0643
Echinococcus granulosus activated cdc42 kinase 1 0.0015 0.0001 0.0001
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0314 0.0835 0.4853
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Echinococcus granulosus titin 0.0018 0.0008 0.0008
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0015 0.0001 0.0006
Trichomonas vaginalis cyclins, putative 0.0017 0.0007 0.0038
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0027 0.0027
Entamoeba histolytica acyl-CoA synthetase, putative 0.0103 0.0245 0.142
Echinococcus granulosus survival motor neuron protein 1 0.0774 0.2116 0.2116
Mycobacterium ulcerans acyl-CoA synthetase 0.0103 0.0245 0.0643
Brugia malayi Myosin head containing protein 0.0019 0.0012 0.0043
Trypanosoma cruzi polo-like protein kinase, putative 0.0247 0.0646 1
Loa Loa (eye worm) TK protein kinase 0.0015 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0007
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0071 0.1083
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0039 0.0067 0.0252
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.0001 0.0005
Echinococcus granulosus enteropeptidase 0.0025 0.0027 0.0027
Echinococcus granulosus neuroglian 0.0041 0.0073 0.0073
Brugia malayi RNA binding protein 0.0065 0.0139 0.0523
Schistosoma mansoni axis inhibition protein axin 0.002 0.0013 0.0013
Entamoeba histolytica hypothetical protein 0.002 0.0013 0.0075
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0073 0.0161 0.0445
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0037 0.056
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0139 0.0139
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0015 0.0001 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0015 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.002 0.0295
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Brugia malayi acetyl-Coenzyme A synthetase 2 0.003 0.0042 0.0159
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0076 0.017 0.017
Echinococcus granulosus kinase suppressor of Ras 1 0.0015 0.0001 0.0001
Echinococcus multilocularis Mastin 0.0025 0.0027 0.0027
Echinococcus multilocularis roundabout 2 0.0056 0.0115 0.0115
Loa Loa (eye worm) patched family protein 0.0019 0.0012 0.0043
Mycobacterium ulcerans hypothetical protein 0.0103 0.0245 0.0643
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0013 0.0076
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.0051 0.019
Schistosoma mansoni protein kinase 0.0015 0.0001 0.0001
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0015 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Schistosoma mansoni cell adhesion molecule 0.0023 0.0022 0.0022
Trichomonas vaginalis AGC family protein kinase 0.0015 0 0.0001
Echinococcus multilocularis cyclins 0.0017 0.0007 0.0007
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0023 0.0023 0.0023
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0025 0.0027 0.0027
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0027 0.0027
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.0044 0.0082 0.0227
Brugia malayi PXA domain containing protein 0.002 0.0013 0.005
Entamoeba histolytica hypothetical protein, conserved 0.0015 0.0001 0.0006
Schistosoma mansoni regulator of G protein signaling 0.002 0.0013 0.0013
Entamoeba histolytica hypothetical protein 0.0015 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Mycobacterium ulcerans aldehyde dehydrogenase 0.0194 0.05 0.1331
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Loa Loa (eye worm) TK/EGFR protein kinase 0.0709 0.1934 0.7253
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.002 0.0015 0.0221
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0033 0.0051 0.019
Loa Loa (eye worm) hypothetical protein 0.0314 0.0835 0.3131
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Schistosoma mansoni nuclear receptor 0.0016 0.0002 0.0002
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0023 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0089 0.0089
Brugia malayi integrin-linked kinase 0.0015 0.0001 0.0005
Entamoeba histolytica serine/threonine kinase, putative 0.0015 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0022 0.0084
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0015 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0013 0.0013
Brugia malayi Calcitonin receptor-like protein seb-1 0.021 0.0545 0.2043
Echinococcus granulosus citrate lyase subunit beta protein 0.0025 0.0028 0.0028
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0114 0.0276 0.0276
Leishmania major 4-coumarate:coa ligase-like protein 0.0103 0.0245 0.378
Echinococcus multilocularis microtubule associated protein 2 0.3603 1 1
Giardia lamblia Hypothetical protein 0.0017 0.0007 0.0085
Plasmodium falciparum protein kinase, putative 0.0015 0.0001 0.0018
Echinococcus multilocularis tyrosine protein kinase csk 0.0015 0.0001 0.0001
Onchocerca volvulus Protein patched homolog 0.0019 0.0012 0.0077
Mycobacterium tuberculosis Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) 0.1303 0.3591 1
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.0023 0.0022 0.0022
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0002 0.0002
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0044 0.0082 0.0309
Onchocerca volvulus 0.0025 0.0027 0.0197
Brugia malayi Protein kinase domain containing protein 0.0156 0.0392 0.147
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0015 0.0001 0.0001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.002 0.029
Brugia malayi hypothetical protein 0.0015 0.0001 0.0005
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0103 0.0245 0.0679
Brugia malayi C-terminal src kinase protein 1 0.0015 0.0001 0.0005
Entamoeba histolytica tyrosine kinase, putative 0.0015 0.0001 0.0006
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0139 0.0139
Brugia malayi serine/threonine-protein kinase plk-2 0.0247 0.0646 0.2423
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0035 0.0056 0.0212
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0033 0.0051 0.019
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0007 0.0038
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0015 0.0001 0.0001
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0037 0.1321
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.0028 0.006
Brugia malayi Fibronectin type III domain containing protein 0.0039 0.0067 0.0252
Echinococcus multilocularis Polycystic kidney disease protein 0.0061 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0033 0.0052 0.0194
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0061 0.0129 0.0485
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0033 0.0051 0.0051
Toxoplasma gondii aurora kinase 0.0115 0.0278 0.4483
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0115 0.0278 0.1614
Schistosoma mansoni kinase 0.026 0.0682 0.0682
Loa Loa (eye worm) oxidoreductase 0.003 0.0042 0.0159
Echinococcus granulosus tyrosine kinase 0.0023 0.0022 0.0022
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0073 0.0161 0.0445
Brugia malayi nuclear receptor RXR 0.0017 0.0007 0.0027
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0016 0.0002 0.0002
Leishmania major protein kinase, putative 0.0115 0.0278 0.4294
Brugia malayi hypothetical protein 0.0025 0.0027 0.0103
Loa Loa (eye worm) hypothetical protein 0.0103 0.0245 0.0918
Loa Loa (eye worm) hypothetical protein 0.0051 0.01 0.0374
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0007
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0015 0.0001 0.0005
Echinococcus multilocularis dna polymerase eta 0.0051 0.01 0.01
Schistosoma mansoni aldehyde dehydrogenase 0.0194 0.05 0.05
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0015 0.0001 0.0005
Echinococcus multilocularis RUN 0.0061 0.0129 0.0129
Entamoeba histolytica hypothetical protein 0.0041 0.0073 0.0419
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0031 0.0083
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0033 0.0051 0.019
Plasmodium falciparum protein kinase, putative 0.002 0.0015 0.0504
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0044 0.0082 0.1262
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0178 0.0455 0.1706
Schistosoma mansoni septate junction protein 0.0017 0.0006 0.0006
Entamoeba histolytica protein kinase, putative 0.0115 0.0278 0.1614
Loa Loa (eye worm) RNA binding protein 0.0065 0.0139 0.0523
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0015 0.0001 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.007 0.0154 0.0896
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0024
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.003 0.0042 0.0098
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0022 0.0084
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0017 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0005
Schistosoma mansoni cell adhesion molecule 0.0049 0.0094 0.0094
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.002 0.0052
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0006 0.008
Echinococcus multilocularis aurora kinase A 0.0115 0.0278 0.0278
Leishmania major hypothetical protein, conserved 0.0024 0.0026 0.0388
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0023 0.0022 0.0022
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0015 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Brugia malayi Trypsin family protein 0.0025 0.0027 0.0103
Echinococcus multilocularis cyclins 0.0017 0.0007 0.0007
Loa Loa (eye worm) TK protein kinase 0.0023 0.0023 0.0084
Loa Loa (eye worm) steroid hormone receptor 0.0033 0.0051 0.019
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Schistosoma mansoni protein kinase 0.0115 0.0278 0.0278
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0073 0.0073
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0051 0.019
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.007 0.0154 0.5545
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0059 0.0123 0.0123
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0006 0.0024
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0027 0.0027
Echinococcus multilocularis ecdysone induced protein 78C 0.0033 0.0051 0.0051
Brugia malayi Nuclear hormone receptor E75 0.0016 0.0002 0.0007
Schistosoma mansoni protein kinase 0.0179 0.0458 0.0458
Entamoeba histolytica serine/threonine kinase, putative 0.0015 0.0001 0.0006
Brugia malayi Protein kinase domain containing protein 0.0451 0.1214 0.4554
Echinococcus multilocularis nervana 2 0.002 0.0014 0.0014
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0022 0.0084
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0014 0.0014
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.003 0.0042 0.0644
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.0028 0.0077
Schistosoma mansoni septate junction protein 0.0017 0.0006 0.0006
Brugia malayi Protein kinase domain containing protein 0.0015 0 0.0002
Echinococcus multilocularis beta adrenergic receptor kinase 0.0025 0.0027 0.0027
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0278 0.1614
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Schistosoma mansoni microtubule-associated protein tau 0.3603 1 1
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0025 0.0028 0.0028
Echinococcus multilocularis tyrosine protein kinase csk 0.0015 0.0001 0.0001
Echinococcus granulosus Mastin 0.0025 0.0027 0.0027
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0037 0.0567
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0247 0.0646 0.2423
Loa Loa (eye worm) hypothetical protein 0.0971 0.2666 1
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0042 0.0098
Echinococcus multilocularis raf serine:threonine protein kinase 0.0015 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.0451 0.1214 0.1214
Echinococcus granulosus contactin 0.0023 0.0022 0.0022
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0015 0.0001 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.0051 0.019
Schistosoma mansoni hypothetical protein 0.0067 0.0144 0.0144
Plasmodium vivax unspecified product 0.007 0.0154 0.5545
Onchocerca volvulus 0.003 0.0042 0.0311
Brugia malayi Protein kinase domain containing protein 0.0047 0.0089 0.0332
Echinococcus multilocularis heat shock protein 70 0.0015 0.0001 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0067 0.0252
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0033 0.0051 0.0373
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Loa Loa (eye worm) RGC/RGC protein kinase 0.0015 0.0001 0.0005
Schistosoma mansoni serine/threonine-protein kinase 0.0027 0.0033 0.0033
Brugia malayi serine/threonine-protein kinase 6 0.0115 0.0278 0.1042
Echinococcus granulosus tyrosine protein kinase Lyn 0.0064 0.0136 0.0136
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0025 0.0027 0.01
Trichomonas vaginalis cyclin B3, putative 0.0017 0.0007 0.0038
Echinococcus granulosus ephrin type A receptor 4 A 0.0082 0.0186 0.0186
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0247 0.0646 0.0646
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.0001 0.0005
Echinococcus multilocularis lipoxygenase domain containing protein 0.0061 0.0129 0.0129
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.002 0.0112
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.021 0.0545 0.2043
Brugia malayi serine/threonine protein kinase 6 0.0115 0.0278 0.1042
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0062 0.0359
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0013 0.0013
Brugia malayi ecdysone receptor 0.0016 0.0002 0.0007
Brugia malayi PXA domain containing protein 0.002 0.0013 0.005
Brugia malayi hypothetical protein 0.0017 0.0007 0.0027
Loa Loa (eye worm) trypsin family protein 0.0025 0.0027 0.0103
Onchocerca volvulus Tyrosine kinase homolog 0.0328 0.0872 0.6589
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.003 0.0042 0.0159
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0001 0.0006
Loa Loa (eye worm) CYP4Cod1 0.0017 0.0006 0.0023
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.003 0.0042 0.0098
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0033 0.0051 0.0051
Echinococcus granulosus mixed lineage leukemia protein mll 0.0033 0.005 0.005
Schistosoma mansoni cyclins 0.0017 0.0007 0.0007
Brugia malayi Doublecortin family protein 0.0061 0.0129 0.0485
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Toxoplasma gondii STE kinase 0.0015 0.0001 0.0008
Brugia malayi Plexin repeat family protein 0.0017 0.0006 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Echinococcus multilocularis lipoxygenase domain containing protein 0.0061 0.0129 0.0129
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Brugia malayi SRC-1 0.0059 0.0123 0.0461
Schistosoma mansoni hypothetical protein 0.013 0.0321 0.0321
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0033 0.0051 0.019
Echinococcus granulosus aurora kinase A 0.0115 0.0278 0.0278
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0042 0.0098
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0071 0.0071
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0025 0.0027 0.0027
Entamoeba histolytica hypothetical protein 0.0015 0.0001 0.0006
Brugia malayi protein kinase C II. 0.0015 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Brugia malayi AMP-binding enzyme family protein 0.0103 0.0245 0.0918
Echinococcus granulosus protein tyrosine kinase 0.0262 0.069 0.069
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0006 0.0024
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0278 0.1614
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0044 0.0082 0.0476
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0115 0.0278 0.1614
Echinococcus granulosus tyrosine protein kinase otk 0.0017 0.0006 0.0006
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0001 0.0003
Echinococcus granulosus defective proboscis extension response 0.0033 0.0052 0.0052
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0114 0.0276 0.0276
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0037 0.0211
Entamoeba histolytica tyrosine kinase, putative 0.0015 0.0001 0.0006
Entamoeba histolytica tyrosin kinase, putative 0.0019 0.001 0.0056
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.002 0.002
Schistosoma mansoni neuroglian 0.0023 0.0022 0.0022
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0047 0.0089 0.0089
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0071 0.0409
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0024
Entamoeba histolytica protein kinase, putative 0.0115 0.0278 0.1614
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0007 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.0646 0.0646
Loa Loa (eye worm) hypothetical protein 0.004 0.0071 0.0265
Echinococcus granulosus cyclin b3 0.0017 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0013 0.0076
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0051 0.0051
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0044 0.0082 0.1262
Schistosoma mansoni tyrosine kinase 0.0483 0.1304 0.1304
Echinococcus granulosus Protein patched homolog 1 0.0135 0.0334 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0013 0.0076
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0015 0.0001 0.0001
Echinococcus granulosus c src tyrosine kinase 0.003 0.0043 0.0043
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Entamoeba histolytica hypothetical protein 0.002 0.0013 0.0075
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Echinococcus multilocularis GPCR, family 2 0.0067 0.0144 0.0144
Brugia malayi SH2 domain containing protein 0.0023 0.0022 0.0084
Plasmodium falciparum cyclin 0.0017 0.0007 0.0216
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0001 0.0001
Brugia malayi hypothetical protein 0.0019 0.0012 0.0043
Echinococcus granulosus casein kinase ii subunit alpha 0.007 0.0154 0.0154
Entamoeba histolytica protein kinase, putative 0.0035 0.0056 0.0326
Mycobacterium ulcerans hypothetical protein 0.0025 0.0028 0.006
Echinococcus granulosus tyrosine protein kinase csk 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0017 0.0006 0.0006
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Echinococcus granulosus tyrosine protein kinase shark 0.0023 0.0022 0.0022
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.002 0.0037
Trypanosoma brucei cdc2-related kinase 3 0.0047 0.0089 0.1363
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.003 0.0042 0.0644
Echinococcus multilocularis transmembrane protease serine 3 0.0025 0.0027 0.0027
Echinococcus granulosus cyclins 0.0017 0.0007 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0037 0.0211
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Brugia malayi Steroid receptor seven-up type 2 0.0033 0.0051 0.019
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0024 0.0026 0.0388
Echinococcus granulosus tyrosine protein kinase ABL1 0.0023 0.0022 0.0022
Onchocerca volvulus 0.0034 0.0053 0.039
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.024 0.1394
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0016 0.0002 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0062 0.0359
Echinococcus granulosus titin 0.0018 0.0008 0.0008
Echinococcus multilocularis protein patched 0.0135 0.0334 0.0334
Brugia malayi Guanylyl cyclase protein 23 0.0015 0.0001 0.0005
Brugia malayi Pre-SET motif family protein 0.043 0.1158 0.4342
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0043 0.0079 0.0079
Brugia malayi bone morphogenetic protein type 1 receptor 0.0015 0.0001 0.0005
Brugia malayi Patched family protein 0.0019 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.005
Entamoeba histolytica hypothetical protein 0.0015 0.0001 0.0006
Schistosoma mansoni tyrosine kinase 0.0483 0.1304 0.1304
Plasmodium falciparum casein kinase 2, alpha subunit 0.007 0.0154 0.5545
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Echinococcus multilocularis roundabout 2 0.0023 0.0022 0.0022
Entamoeba histolytica acyl-coA synthetase, putative 0.0103 0.0245 0.142
Loa Loa (eye worm) TK protein kinase 0.0015 0.0001 0.0005
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.005
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Loa Loa (eye worm) RGC/RGC protein kinase 0.0015 0.0001 0.0005
Schistosoma mansoni polycystin 1-related 0.0061 0.0129 0.0129
Entamoeba histolytica protein kinase 2, putative 0.0025 0.0028 0.016
Echinococcus multilocularis cyclin dependent kinase 5 0.0047 0.0089 0.0089
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.0044 0.0082 0.0206
Loa Loa (eye worm) hypothetical protein 0.0103 0.0245 0.0918
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0006 0.0024
Loa Loa (eye worm) doublecortin family protein 0.0061 0.0129 0.0485
Mycobacterium ulcerans hypothetical protein 0.0025 0.0028 0.006
Onchocerca volvulus 0.0025 0.0027 0.0197
Onchocerca volvulus 0.0025 0.0027 0.0197
Echinococcus multilocularis protein tyrosine kinase 0.0262 0.069 0.069
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0077 0.0172 0.0448
Onchocerca volvulus 0.0305 0.0808 0.6104
Entamoeba histolytica ankyrin repeat protein 0.0015 0.0001 0.0006
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0052 0.0102 0.0591
Brugia malayi hypothetical protein 0.0076 0.017 0.0636
Onchocerca volvulus Protein patched homolog 0.0019 0.0012 0.0077
Brugia malayi ImpB/MucB/SamB family protein 0.0051 0.01 0.0377
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.005
Loa Loa (eye worm) RGS-3 protein 0.002 0.0013 0.005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.002 0.029
Echinococcus multilocularis protein kinase 0.0015 0.0001 0.0001
Onchocerca volvulus 0.0061 0.0129 0.0969
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0044 0.0082 0.0477
Brugia malayi Protein kinase domain containing protein 0.0037 0.0062 0.0233
Brugia malayi hypothetical protein 0.0041 0.0073 0.0272
Schistosoma mansoni tyrosine kinase 0.003 0.0043 0.0043
Plasmodium vivax tyrosine kinase-like protein, putative 0.0015 0.0001 0.0018
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0037 0.0211
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0013 0.0013
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0062 0.0359
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0062 0.0359
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0013 0.005
Trichomonas vaginalis cyclin B, putative 0.0017 0.0007 0.0038
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0025 0.0028 0.0163
Echinococcus granulosus cyclin dependent kinase 5 0.0047 0.0089 0.0089
Trichomonas vaginalis cyclins, putative 0.0017 0.0007 0.0038
Trichomonas vaginalis antibiotic synthetase, putative 0.003 0.0042 0.0245
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.0051 0.019
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0015 0.0001 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0022 0.0082
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0023 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0033 0.0051 0.019
Trichomonas vaginalis TK family protein kinase 0.0015 0.0001 0.0006
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.003 0.0042 0.0116
Brugia malayi Protein kinase domain containing protein 0.0023 0.0022 0.0084
Plasmodium falciparum acetyl-CoA synthetase, putative 0.003 0.0042 0.1499
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0037 0.0216
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0037 0.0211
Echinococcus multilocularis tyrosine protein kinase pr2 0.0015 0.0001 0.0001
Echinococcus granulosus retinal guanylyl cyclase 2 0.0015 0.0001 0.0001
Echinococcus granulosus dna polymerase kappa 0.0022 0.002 0.002
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Schistosoma mansoni hypothetical protein 0.0025 0.0027 0.0027
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0071 0.0409
Entamoeba histolytica tyrosine kinase, putative 0.0015 0.0001 0.0006
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Entamoeba histolytica tyrosine kinase, putative 0.0015 0.0001 0.0006
Loa Loa (eye worm) patched family protein 0.0019 0.0012 0.0043
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0006 0.0023
Echinococcus granulosus glycoprotein Antigen 5 0.0025 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0027
Brugia malayi hypothetical protein 0.0016 0.0002 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0033 0.0051 0.019
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.0001 0.0005
Echinococcus granulosus GPCR family 2 0.0067 0.0144 0.0144
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0194 0.05 0.05
Echinococcus granulosus thyroid hormone receptor alpha 0.0016 0.0002 0.0002
Echinococcus granulosus protein kinase 0.0015 0.0001 0.0001
Echinococcus multilocularis enteropeptidase 0.0025 0.0027 0.0027
Echinococcus granulosus roundabout 2 0.0056 0.0115 0.0115
Loa Loa (eye worm) TK protein kinase 0.0015 0.0001 0.0005
Plasmodium vivax acyl-CoA synthetase, putative 0.0077 0.0172 0.6188
Schistosoma mansoni hypothetical protein 0.0067 0.0144 0.0144
Schistosoma mansoni vesicular amine transporter 0.0033 0.0052 0.0052
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0015 0.0001 0.0001
Loa Loa (eye worm) histone methyltransferase 0.0041 0.0071 0.0268
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0006 0.0024
Entamoeba histolytica protein kinase domain containing protein 0.002 0.0015 0.0084
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0022 0.0084
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0015 0.0001 0.0001
Entamoeba histolytica ankyrin repeat protein 0.0015 0.0001 0.0006
Brugia malayi hypothetical protein 0.0015 0.0001 0.0005
Schistosoma mansoni cell adhesion molecule 0.0023 0.0022 0.0022
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0306 0.0812 0.0812
Giardia lamblia DINP protein human, muc B family 0.0022 0.002 0.0283
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0022 0.0084
Echinococcus multilocularis FL cytokine receptor 0.0015 0.0001 0.0001
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0033 0.0051 0.0051
Echinococcus multilocularis protein dispatched 1 0.0154 0.0388 0.0388
Echinococcus granulosus activated cdc42 kinase 1 0.0015 0.0001 0.0001
Entamoeba histolytica serine/threonine protein kinase, putative 0.0247 0.0646 0.3754
Echinococcus granulosus lipoxygenase domain containing protein 0.0061 0.0129 0.0129
Echinococcus multilocularis epidermal growth factor receptor 0.0498 0.1347 0.1347
Entamoeba histolytica tyrosine kinase, putative 0.0015 0.0001 0.0006
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Mycobacterium ulcerans aldehyde dehydrogenase 0.0194 0.05 0.1331
Trichomonas vaginalis cyclin D, putative 0.0017 0.0007 0.0038
Loa Loa (eye worm) CAMK/CAMKL/NUAK protein kinase 0.0482 0.1302 0.4884
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0001 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0001 0.0006
Trypanosoma brucei Casein kinase II 0.007 0.0154 0.2385
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0017 0.0007 0.0007
Echinococcus granulosus tyrosine kinase 0.0015 0.0001 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0022 0.0022
Schistosoma mansoni tsg101-related 0.0052 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Trichomonas vaginalis AGC family protein kinase 0.0015 0 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0027 0.0027
Echinococcus granulosus natriuretic peptide receptor 1 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0027 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0013 0.0076
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0033 0.0051 0.019
Toxoplasma gondii CMGC kinase, CK2 family 0.007 0.0154 0.2485
Loa Loa (eye worm) AGC/NDR protein kinase 0.0015 0 0.0002
Schistosoma mansoni protein kinase 0.0015 0.0001 0.0001
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0025 0.0028 0.0028
Echinococcus multilocularis tyrosine protein kinase csk 0.0015 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0018 0.0008 0.0031
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0033 0.0051 0.0051
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0033 0.005 0.005
Brugia malayi Cytochrome P450 family protein 0.0017 0.0006 0.0023
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0027 0.0027
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0015 0.0001 0.0006
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0015 0.0001 0.0006
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0071 0.0265
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0036 0.0059 0.0059
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.003 0.0043 0.0043
Entamoeba histolytica cell division protein kinase 2, putative 0.0047 0.0089 0.0513
Schistosoma mansoni roundabout 0.0017 0.0006 0.0006
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0015 0.0001 0.0006
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0033 0.005 0.005
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0067 0.0144 0.0144
Leishmania major hypothetical protein, conserved 0.0015 0.0001 0.0008
Trypanosoma cruzi casein kinase II, putative 0.007 0.0154 0.2381
Schistosoma mansoni patched 1 0.0135 0.0334 0.0334
Mycobacterium leprae Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase) 0.1348 0.3715 1
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Schistosoma mansoni RAR-like nuclear receptor 0.0033 0.0051 0.0051
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0025 0.0027 0.01
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0023 0.0022 0.0128
Schistosoma mansoni cpg binding protein 0.0131 0.0323 0.0323
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0025 0.0028 0.0974
Trichomonas vaginalis CAMK family protein kinase 0.0247 0.0646 0.3754
Brugia malayi serine/threonine kinase 12 0.0115 0.0278 0.1042
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0001 0.0001
Schistosoma mansoni coup transcription factor 0.0033 0.0051 0.0051
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Mycobacterium ulcerans acetyl-CoA synthetase 0.003 0.0042 0.0098
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0044 0.0082 0.1318
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0027
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Entamoeba histolytica hypothetical protein 0.0015 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0024
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0027 0.0027
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.003 0.0042 0.0116
Schistosoma mansoni cpg binding protein 0.0131 0.0323 0.0323
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.002 0.0295
Toxoplasma gondii histone lysine methyltransferase SET1 0.0237 0.0619 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0005
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0033 0.0051 0.019
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Onchocerca volvulus 0.0019 0.0012 0.0077
Echinococcus multilocularis natriuretic peptide receptor 1 0.0015 0.0001 0.0001
Brugia malayi Patched protein homolog 1 0.0019 0.0012 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.002 0.0295
Brugia malayi Immunoglobulin I-set domain containing protein 0.0018 0.0008 0.0031
Echinococcus multilocularis insulin receptor 0.0451 0.1214 0.1214
Schistosoma mansoni protein kinase 0.0015 0.0001 0.0001
Loa Loa (eye worm) TK/Met protein kinase 0.0015 0.0001 0.0005
Brugia malayi hypothetical protein 0.0039 0.0067 0.0252
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0016 0.0002 0.0002
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0033 0.0051 0.0051
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0033 0.0052 0.0052
Schistosoma mansoni zinc finger protein 0.0016 0.0002 0.0002
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0137 0.0137
Echinococcus multilocularis 0.03 0.0795 0.0795
Echinococcus granulosus Polycystic kidney disease protein 0.0061 0.0129 0.0129
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0023 0.0022 0.0022
Brugia malayi nuclear hormone receptor 0.0033 0.0051 0.019
Loa Loa (eye worm) TK protein kinase 0.0052 0.0102 0.0383
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0015 0.0001 0.0001
Onchocerca volvulus 0.0023 0.0022 0.016
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0265 0.0697 0.0697
Brugia malayi Patched family protein 0.0019 0.0012 0.0043
Trichomonas vaginalis cyclin B, putative 0.0017 0.0007 0.0038
Trypanosoma brucei polo-like protein kinase 0.0247 0.0646 1
Plasmodium falciparum serine/threonine protein kinase, putative 0.0115 0.0278 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0006 0.0023
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.003 0.0042 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0033 0.0051 0.019
Echinococcus granulosus RUN 0.0061 0.0129 0.0129
Entamoeba histolytica cyclin, putative 0.0017 0.0007 0.0038
Loa Loa (eye worm) TK/ACK protein kinase 0.0015 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0077 0.0172 0.0646
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0178 0.0455 0.0455
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Plasmodium falciparum tyrosine kinase-like protein 0.0015 0.0001 0.0018
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0013 0.0076
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.002 0.029
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0027 0.0027
Trypanosoma cruzi cyclin 6, putative 0.0017 0.0007 0.0093
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0001 0.0006
Echinococcus granulosus retinal guanylyl cyclase 2 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.005
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.002 0.0112
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0028 0.0035 0.0133
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0008 0.0008
Loa Loa (eye worm) plexin A 0.002 0.0014 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.002 0.0295
Echinococcus multilocularis tyrosine protein kinase 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0027 0.0103
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0033 0.0051 0.019
Schistosoma mansoni lipoxygenase 0.0196 0.0504 0.0504
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Echinococcus granulosus nuclear receptor nhr 48 0.0016 0.0002 0.0002
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0025 0.0027 0.01
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0015 0.0001 0.0006
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0007 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0022 0.0084
Echinococcus granulosus tyrosine protein kinase Fyn 0.0059 0.0123 0.0123
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0139 0.0523
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.002 0.0295
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0306 0.0812 0.0812
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0023 0.0022 0.0022
Entamoeba histolytica hypothetical protein 0.0015 0.0001 0.0006
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.1348 0.3715 1
Echinococcus granulosus roundabout 2 0.0023 0.0022 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0013 0.0076
Brugia malayi Latrophilin receptor protein 2 0.0067 0.0144 0.054
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.003 0.0042 0.0098
Loa Loa (eye worm) hypothetical protein 0.0043 0.0079 0.0295
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0042 0.0098
Trichomonas vaginalis CMGC family protein kinase 0.007 0.0154 0.0896
Brugia malayi Trypsin family protein 0.0025 0.0027 0.0103
Echinococcus multilocularis tyrosine protein kinase otk 0.0017 0.0006 0.0006
Trichomonas vaginalis set domain proteins, putative 0.0489 0.1322 0.7688
Schistosoma mansoni cyclin B3 0.0017 0.0007 0.0007
Entamoeba histolytica PH domain containing protein kinase, putative 0.0027 0.0033 0.0192
Onchocerca volvulus 0.0016 0.0002 0.0004
Echinococcus granulosus cpg binding protein 0.0131 0.0323 0.0323
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.002 0.0015 0.0226
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.002 0.0295
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0047 0.0089 0.0332
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0137 0.0137
Schistosoma mansoni thyroid hormone receptor 0.0033 0.0051 0.0051
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0047 0.0089 0.1359
Leishmania major hypothetical protein, conserved 0.0218 0.0567 0.877
Entamoeba histolytica hypothetical protein 0.0015 0.0001 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0037 0.0211
Loa Loa (eye worm) protein kinase domain-containing protein 0.0015 0.0001 0.0005
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0028 0.0426
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0067 0.0144 0.054
Schistosoma mansoni hypothetical protein 0.0067 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.007 0.0154 0.0896
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0006 0.0024
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0028 0.006
Echinococcus multilocularis cyclins 0.0017 0.0007 0.0007
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.002 0.0014 0.0014
Plasmodium falciparum LCCL domain-containing protein 0.0061 0.0129 0.4639
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0042 0.0098
Loa Loa (eye worm) hypothetical protein 0.0033 0.0051 0.019
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0037 0.0211
Schistosoma mansoni nuclear receptor 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0039 0.0067 0.0252
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0037 0.0567
Toxoplasma gondii patched family protein 0.0019 0.0012 0.0172
Loa Loa (eye worm) hypothetical protein 0.0774 0.2116 0.7938
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Loa Loa (eye worm) patched family protein 0.0019 0.0012 0.0043
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.003 0.0042 0.0116
Echinococcus multilocularis cyclins 0.0017 0.0007 0.0007
Brugia malayi Tyrosine-protein kinase abl-1 0.003 0.0043 0.0161
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0015 0.0001 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0089 0.0513
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0033 0.0051 0.0051
Loa Loa (eye worm) SRC-1 0.0059 0.0123 0.0461
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Entamoeba histolytica cyclin family protein 0.0017 0.0007 0.0038
Echinococcus multilocularis tyrosine protein kinase Blk 0.0052 0.0102 0.0102
Echinococcus granulosus nervana 2 0.002 0.0014 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0001 0.0001
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0115 0.0278 0.0278
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0073 0.0161 0.0445
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Echinococcus multilocularis cyclins 0.0017 0.0007 0.0007
Loa Loa (eye worm) latrophilin receptor protein 2 0.0067 0.0144 0.054
Onchocerca volvulus 0.0017 0.0007 0.0042
Schistosoma mansoni tyrosine kinase 0.0498 0.1347 0.1347
Loa Loa (eye worm) hypothetical protein 0.0033 0.0051 0.019
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0015 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0033 0.0052 0.0194
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0137 0.0137
Echinococcus granulosus twitchin 0.0046 0.0086 0.0086
Trichomonas vaginalis CAMK family protein kinase 0.0247 0.0646 0.3754
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0076 0.017 0.0636
Brugia malayi cell division control protein 2 homolog 0.0047 0.0089 0.0332
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0016 0.0002 0.0002
Entamoeba histolytica cyclin family protein 0.0017 0.0007 0.0038
Schistosoma mansoni protein tyrosine kinase 0.0015 0.0001 0.0001
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0103 0.0245 0.0643
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0033 0.0051 0.019
Echinococcus granulosus epidermal growth factor receptor 0.0709 0.1934 0.1934
Echinococcus granulosus serine threonine protein kinase nrc 0.0025 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0067 0.0144 0.054
Loa Loa (eye worm) TK/FAK protein kinase 0.0265 0.0698 0.2618
Schistosoma mansoni nephrin 0.0047 0.0088 0.0088
Brugia malayi Patched family protein 0.0019 0.0012 0.0043
Echinococcus multilocularis dna polymerase kappa 0.0022 0.002 0.002
Brugia malayi protein C24B5.3 0.0019 0.0012 0.0043
Trypanosoma brucei Flagellum attachment zone protein 20 0.0015 0.0001 0.0012
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0015 0.0001 0.0001
Trichomonas vaginalis cyclin A, putative 0.0017 0.0007 0.0038
Loa Loa (eye worm) patched family protein 0.0019 0.0012 0.0043
Entamoeba histolytica tyrosine kinase, putative 0.0015 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0077 0.0172 0.0646
Onchocerca volvulus 0.0054 0.0108 0.0804
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0071 0.1076
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0015 0 0.0002
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0037 0.0211
Trichomonas vaginalis cyclin B, putative 0.0017 0.0007 0.0038
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0013 0.005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0026
Trypanosoma brucei DNA polymerase eta, putative 0.0051 0.01 0.1547
Brugia malayi nuclear hormone receptor family member odr-7 0.0016 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.014 0.0349 0.1308
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0044 0.0082 0.294
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.003 0.0042 0.0098
Brugia malayi Protein kinase domain containing protein 0.0023 0.0022 0.0084
Echinococcus multilocularis protein KINase family member (kin 25) 0.0015 0.0001 0.0001
Entamoeba histolytica cyclin, putative 0.0017 0.0007 0.0038
Loa Loa (eye worm) hypothetical protein 0.0144 0.0359 0.1347
Echinococcus multilocularis cyclin b3 0.0017 0.0007 0.0007
Entamoeba histolytica tyrosine kinase, putative 0.0015 0.0001 0.0006
Echinococcus multilocularis receptor type guanylyl cyclase 0.0015 0.0001 0.0001
Entamoeba histolytica tyrosine kinase, putative 0.0015 0.0001 0.0006
Plasmodium falciparum protein kinase 5 0.0047 0.0089 0.3165
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0033 0.0051 0.019
Echinococcus multilocularis neuroglian 0.0023 0.0022 0.0022
Brugia malayi AMP-binding enzyme family protein 0.0103 0.0245 0.0918
Schistosoma mansoni tsg101-related 0.0063 0.0134 0.0134
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0044 0.0082 0.0476
Schistosoma mansoni DNA polymerase eta 0.0051 0.01 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0001 0.0006
Schistosoma mansoni tyrosine protein kinase 0.0015 0.0001 0.0001
Brugia malayi Patched family protein 0.0019 0.0012 0.0043
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0015 0.0001 0.0012
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0059 0.0123 0.0123
Schistosoma mansoni hypothetical protein 0.013 0.0321 0.0321
Mycobacterium ulcerans aldehyde dehydrogenase 0.0194 0.05 0.1331
Echinococcus multilocularis epidermal growth factor receptor 0.0709 0.1934 0.1934
Brugia malayi AMP-binding enzyme family protein 0.003 0.0042 0.0159
Echinococcus multilocularis hemicentin 1 0.0017 0.0006 0.0006
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0071 0.1083
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0071 0.0071
Brugia malayi conserved hypotetical protein 0.0016 0.0002 0.0007
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.002 0.0052
Brugia malayi isocitrate dehydrogenase 0.0015 0.0001 0.0003
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0016 0.0002 0.0004
Loa Loa (eye worm) CAMK protein kinase 0.0018 0.0008 0.0031
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0037 0.0211
Trypanosoma cruzi DNA polymerase eta, putative 0.0051 0.01 0.1543
Plasmodium vivax acetyl-CoA synthetase, putative 0.003 0.0042 0.1499
Echinococcus multilocularis plexin a4 0.002 0.0014 0.0014
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0073 0.0073
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Loa Loa (eye worm) serine/threonine protein kinase 0.0015 0.0001 0.0005
Onchocerca volvulus 0.0023 0.0022 0.016
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0006 0.008
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.0001 0.0005
Schistosoma mansoni rab6-interacting 0.0061 0.0129 0.0129
Loa Loa (eye worm) TK/DDR protein kinase 0.0015 0.0001 0.0005
Brugia malayi Hr1 repeat family protein 0.0015 0 0.0002
Schistosoma mansoni nephrin 0.0023 0.0022 0.0022
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0042 0.0098
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.002 0.0037
Brugia malayi Furin-like cysteine rich region family protein 0.0709 0.1934 0.7253
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Echinococcus multilocularis transfer RNA-Thr 0.0015 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Loa Loa (eye worm) TK/CSK protein kinase 0.0015 0.0001 0.0005
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0247 0.0646 1
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0015 0.0001 0.0008
Schistosoma mansoni protein kinase 0.0179 0.0458 0.0458
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.002 0.0295
Echinococcus multilocularis thyroid hormone receptor alpha 0.0033 0.0051 0.0051
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.002 0.002
Leishmania major acetyl-CoA synthetase, putative 0.003 0.0042 0.0644
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.003 0.0042 0.0098
Onchocerca volvulus 0.0025 0.0027 0.0197
Echinococcus granulosus tyrosine protein kinase Blk 0.0052 0.0102 0.0102
Echinococcus multilocularis activin receptor type 0.002 0.0015 0.0015
Echinococcus granulosus integrin linked protein kinase 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0007
Leishmania major protein kinase, putative 0.002 0.0015 0.0217
Brugia malayi Nuclear hormone receptor E75 0.0016 0.0002 0.0007
Entamoeba histolytica hypothetical protein 0.0041 0.0073 0.0419
Trypanosoma cruzi polo-like protein kinase, putative 0.0247 0.0646 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0027 0.0027
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0016 0.0002 0.0007
Trichomonas vaginalis protein kinase atn1, putative 0.0015 0.0001 0.0006
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Echinococcus granulosus serine/threonine protein kinase 0.0027 0.0033 0.0033
Brugia malayi nuclear receptor NHR-67 0.0016 0.0002 0.0007
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0033 0.0051 0.0051
Echinococcus multilocularis survival motor neuron protein 1 0.0774 0.2116 0.2116
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Brugia malayi Protein kinase domain containing protein 0.0015 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0103 0.0245 0.0643
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Schistosoma mansoni tyrosine kinase 0.0023 0.0022 0.0022
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Entamoeba histolytica hypothetical protein 0.0015 0.0001 0.0006
Loa Loa (eye worm) nuclear receptor NHR-67 0.0016 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Schistosoma mansoni hypothetical protein 0.0144 0.0359 0.0359
Loa Loa (eye worm) hypothetical protein 0.0025 0.0027 0.0103
Loa Loa (eye worm) hypothetical protein 0.0031 0.0044 0.0166
Brugia malayi Cyclin, N-terminal domain containing protein 0.0017 0.0007 0.0026
Mycobacterium tuberculosis Conserved protein 0.0025 0.0028 0.0077
Onchocerca volvulus 0.0023 0.0022 0.016
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0077 0.0172 0.5
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0051 0.0051
Onchocerca volvulus 0.0019 0.0012 0.0077
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0007
Echinococcus granulosus hemicentin 1 0.0017 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0067 0.0144 0.0144
Schistosoma mansoni lipoxygenase 0.0306 0.0812 0.0812
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0089 0.0089
Loa Loa (eye worm) DR-78 0.0016 0.0002 0.0007
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0059 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Echinococcus multilocularis Glutaredoxin protein 5 0.002 0.0014 0.0014
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0013 0.0013
Brugia malayi F/Y-rich N-terminus family protein 0.004 0.007 0.0263
Echinococcus multilocularis sterol regulatory element binding protein 0.0135 0.0334 0.0334
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0022 0.0082
Echinococcus multilocularis cyclin B3 1 0.0017 0.0007 0.0007
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0013 0.005
Schistosoma mansoni hypothetical protein 0.0061 0.0129 0.0129
Echinococcus multilocularis tyrosine protein kinase csk 0.0015 0.0001 0.0001
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0007 0.0027
Trichomonas vaginalis CMGC family protein kinase 0.007 0.0154 0.0896
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0033 0.0051 0.019
Loa Loa (eye worm) hypothetical protein 0.0025 0.0027 0.0103
Leishmania major DNA polymerase eta, putative 0.0051 0.01 0.1543
Loa Loa (eye worm) TK/INSR protein kinase 0.0451 0.1214 0.4554
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0033 0.0051 0.019
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0015 0.0001 0.0006
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0071 0.0071
Brugia malayi hypothetical protein 0.0017 0.0007 0.0027
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0015 0.0001 0.0001
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.003 0.0042 0.0672
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0015 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Brugia malayi hypothetical protein 0.0019 0.0012 0.0043
Trichomonas vaginalis cyclins, putative 0.0017 0.0007 0.0038
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0015 0.0001 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0218 0.0567 0.877
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0025 0.0027 0.0027
Entamoeba histolytica hypothetical protein 0.0015 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0024
Giardia lamblia Kinase, PLK 0.0247 0.0646 1
Brugia malayi nuclear receptor NHR-88 0.0033 0.0051 0.019
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0013 0.005
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0137 0.22
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0015 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.002 0.0295
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Loa Loa (eye worm) TK/EPH protein kinase 0.0084 0.0192 0.0718
Mycobacterium ulcerans hypothetical protein 0.0025 0.0027 0.0057
Brugia malayi Patched family protein 0.0019 0.0012 0.0043
Echinococcus granulosus sterol regulatory element binding protein 0.0135 0.0334 0.0334
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0455 0.0455
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.003 0.0042 0.0116
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0178 0.0455 0.0455
Brugia malayi tailless protein 0.0016 0.0002 0.0007
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0023 0.0022 0.0022
Brugia malayi hypothetical protein 0.0061 0.0129 0.0485
Echinococcus multilocularis cyclin dependent kinase 0.0047 0.0089 0.0089
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.002 0.0295
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0017 0.0007 0.0093
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0015 0.0001 0.0005
Onchocerca volvulus 0.0019 0.0012 0.0077
Onchocerca volvulus 0.0019 0.0012 0.0077
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0178 0.0455 0.3432
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0007
Echinococcus granulosus cyclins 0.0017 0.0007 0.0007
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0033 0.0051 0.0051
Trichomonas vaginalis protein tyrosine kinase, putative 0.0015 0.0001 0.0006
Loa Loa (eye worm) TK/ABL protein kinase 0.0023 0.0022 0.0084
Brugia malayi SH2 domain containing protein 0.0023 0.0022 0.0084
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0082
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0007
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0178 0.0455 0.1706
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0013 0.0013
Loa Loa (eye worm) RGC/RGC protein kinase 0.0015 0.0001 0.0005
Schistosoma mansoni survival motor neuron protein 0.0158 0.0398 0.0398
Plasmodium falciparum protein kinase, putative 0.0015 0.0001 0.0018
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0013 0.005
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0042 0.0098
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0015 0.0001 0.0006
Brugia malayi Casein kinase II, alpha chain 0.007 0.0154 0.0579
Toxoplasma gondii propionate-CoA ligase 0.003 0.0042 0.0672
Schistosoma mansoni cpg binding protein 0.0124 0.0304 0.0304
Schistosoma mansoni nuclear receptor nhr-48 0.0016 0.0002 0.0002
Echinococcus granulosus cyclins 0.0017 0.0007 0.0007
Entamoeba histolytica receptor protein kinase, putative 0.0015 0.0001 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0135 0.0334 0.1943
Echinococcus multilocularis Immunoglobulin 0.0033 0.0052 0.0052
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0067 0.0144 0.0144
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Plasmodium vivax tyrosine kinase-like protein, putative 0.0015 0.0001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0005
Trypanosoma cruzi aurora B kinase, putative 0.0115 0.0278 0.4294
Schistosoma mansoni titin 0.0018 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0077 0.0172 0.0646
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0013 0.0013
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0135 0.0334 0.1255
Trichomonas vaginalis cyclin D, putative 0.0017 0.0007 0.0038
Brugia malayi latrophilin 2 splice variant baaae 0.0144 0.0359 0.1347
Trypanosoma cruzi hypothetical protein, conserved 0.0218 0.0567 0.877
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0001 0.0005
Giardia lamblia Cyclin A 0.0017 0.0007 0.0085
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0062 0.0359
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0013 0.005
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Brugia malayi ephrin receptor 1 precursor 0.0041 0.0072 0.0269
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0247 0.0646 0.0646
Brugia malayi Cyclin, N-terminal domain containing protein 0.0017 0.0007 0.0026
Onchocerca volvulus Serine\/threonine kinase homolog 0.0247 0.0646 0.4879
Echinococcus granulosus muscleblind protein 0.0971 0.2666 0.2666
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0115 0.0278 0.0278
Entamoeba histolytica tyrosine kinase, putative 0.0015 0.0001 0.0006
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0047 0.0089 0.1419
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0037 0.0211
Entamoeba histolytica tyrosine kinase, putative 0.0015 0.0001 0.0006
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0028 0.006
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0062 0.0359
Brugia malayi Patched family protein 0.0019 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0007
Echinococcus multilocularis glycoprotein Antigen 5 0.0025 0.0027 0.0027
Echinococcus multilocularis kinase suppressor of Ras 1 0.0015 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0007 0.0007
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0006 0.0024
Trypanosoma brucei protein kinase, putative 0.002 0.0015 0.0221
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.003 0.0042 0.0116
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0047 0.0089 0.0332
Entamoeba histolytica protein kinase domain containing protein 0.0115 0.0278 0.1614
Onchocerca volvulus 0.0124 0.0304 0.2288
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.002 0.0074
Echinococcus multilocularis muscleblind protein 1 0.0971 0.2666 0.2666
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0456 0.123 0.123
Echinococcus granulosus epidermal growth factor receptor 0.0498 0.1347 0.1347
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0044 0.0082 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0027 0.0027
Entamoeba histolytica protein kinase , putative 0.0115 0.0278 0.1614
Entamoeba histolytica PH domain containing protein kinase, putative 0.0027 0.0033 0.0192
Brugia malayi Pre-SET motif family protein 0.0064 0.0137 0.0513
Echinococcus granulosus neuroglian 0.0023 0.0022 0.0022
Echinococcus granulosus tyrosine protein kinase Fyn 0.0059 0.0123 0.0123
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0023 0.0022 0.0022
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0015 0.0001 0.0006
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.002 0.002
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0027 0.0027
Brugia malayi Muscleblind-like protein 0.0971 0.2666 1
Schistosoma mansoni regulator of G protein signaling 0.002 0.0013 0.0013
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0015 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0071 0.0071
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0059 0.0123 0.0123
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.003 0.0042 0.0116
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Entamoeba histolytica hypothetical protein 0.0015 0.0001 0.0006
Brugia malayi Niemann-Pick C1 protein precursor 0.0314 0.0835 0.3131
Toxoplasma gondii aldehyde dehydrogenase 0.0194 0.05 0.8075
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0077 0.0172 0.0477
Schistosoma mansoni rab6-interacting 0.0061 0.0129 0.0129
Onchocerca volvulus 0.0158 0.0398 0.3006
Brugia malayi AMP-binding enzyme family protein 0.003 0.0042 0.0159
Schistosoma mansoni cyclin B 0.0017 0.0007 0.0007
Brugia malayi orphan nuclear receptor NR2E1 0.0016 0.0002 0.0007
Brugia malayi hypothetical protein 0.0061 0.0129 0.0485
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0044 0.0082 0.0082
Echinococcus multilocularis FTZ F1 alpha 0.0033 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0007
Echinococcus multilocularis integrin linked protein kinase 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0033 0.0051 0.019
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2655 0.7358 0.7358
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0013 0.0013
Trichomonas vaginalis cyclins, putative 0.0017 0.0007 0.0038
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0015 0.0001 0.0006
Schistosoma mansoni regulator of G protein signaling 0.002 0.0013 0.0013
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0015 0.0001 0.0001
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0027 0.0033 0.0505
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0025 0.0027 0.0103
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0037 0.0141
Loa Loa (eye worm) TK/ROR protein kinase 0.0023 0.0023 0.0084
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0007 0.0007
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.002 0.0074
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0015 0.0001 0.0006
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0022 0.0084
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Entamoeba histolytica tyrosine kinase, putative 0.0015 0.0001 0.0006
Entamoeba histolytica protein kinase, putative 0.0037 0.0062 0.0359
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0042 0.0075 0.0282
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0033 0.0052 0.0052
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0036 0.0058 0.0928
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0013 0.0076
Leishmania major DNA polymerase kappa, putative 0.0022 0.002 0.029
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0062 0.0359
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0165 0.0419 0.1572
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Loa Loa (eye worm) TK/FER protein kinase 0.0015 0.0001 0.0005
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0052 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0005
Onchocerca volvulus 0.0018 0.0008 0.0053
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Loa Loa (eye worm) nuclear hormone receptor 0.0016 0.0002 0.0007
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0076 0.017 0.017
Echinococcus multilocularis nuclear receptor nhr 48 0.0016 0.0002 0.0002
Schistosoma mansoni tyrosine kinase 0.0483 0.1304 0.1304
Leishmania major DNA polymerase eta, putative 0.0036 0.0058 0.0889
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Echinococcus granulosus tyrosine protein kinase Src64B 0.0059 0.0123 0.0123
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0001 0.0003
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0007 0.0007
Trypanosoma cruzi cdc2-related kinase 1 0.0047 0.0089 0.1359
Giardia lamblia Aurora kinase 0.0115 0.0278 0.429
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0024
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.003 0.0042 0.0244
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0027 0.0027
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.003 0.0042 0.0672
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0037 0.0216
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.0058 0.0889
Echinococcus granulosus ecdysone induced protein 78C 0.0033 0.0051 0.0051
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0005
Brugia malayi Trypsin-like protease protein 5 0.0025 0.0027 0.0103
Echinococcus multilocularis tyrosine protein kinase shark 0.0023 0.0022 0.0022
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0051 0.0051
Trypanosoma brucei aurora B kinase 0.0115 0.0278 0.4297
Echinococcus granulosus Immunoglobulin 0.0033 0.0052 0.0052
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0071 0.1083
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0059 0.0123 0.0123
Schistosoma mansoni ephrin receptor 0.0069 0.0151 0.0151
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.003 0.0042 0.0116
Schistosoma mansoni hypothetical protein 0.0025 0.0027 0.0027
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0013 0.0013
Brugia malayi Protein kinase domain containing protein 0.0023 0.0022 0.0084
Brugia malayi protein C24B5.3 0.0019 0.0012 0.0043
Entamoeba histolytica hypothetical protein 0.0041 0.0073 0.0419
Leishmania major protein kinase, putative 0.0015 0.0001 0.0008
Giardia lamblia Protein 21.1 0.0015 0.0001 0.00000011109
Echinococcus granulosus lipoxygenase domain containing protein 0.0061 0.0129 0.0129
Brugia malayi Flap endonuclease-1 0.0028 0.0037 0.0141
Leishmania major casein kinase II, putative 0.007 0.0154 0.2381
Echinococcus multilocularis neuroglian 0.0041 0.0073 0.0073
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0059 0.0123 0.0123
Schistosoma mansoni acetyl-CoA synthetase 0.003 0.0042 0.0042
Schistosoma mansoni flap endonuclease-1 0.0026 0.003 0.003
Brugia malayi hypothetical protein 0.0019 0.0012 0.0043
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0033 0.0051 0.0051
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Echinococcus granulosus tyrosine protein kinase HCK 0.0044 0.0081 0.0081
Entamoeba histolytica hypothetical protein 0.0015 0.0001 0.0006
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.002 0.002
Plasmodium vivax protein kinase, putative 0.002 0.0013 0.0441
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0278 0.1614
Entamoeba histolytica serine/threonine kinase, putative 0.0015 0.0001 0.0006
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0025 0.0028 0.0418
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0027
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0015 0.0001 0.0006
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0363 0.0971 0.3642
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0037 0.0592
Entamoeba histolytica tyrosin kinase, putative 0.0015 0.0001 0.0006
Brugia malayi Patched family protein 0.0019 0.0012 0.0043
Entamoeba histolytica tyrosine kinase, putative 0.0015 0.0001 0.0006
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.003 0.0042 0.0644
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0024
Entamoeba histolytica protein kinase, putative 0.0018 0.0007 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0278 0.0278
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0194 0.05 0.139
Loa Loa (eye worm) hypothetical protein 0.0051 0.01 0.0374
Loa Loa (eye worm) RGC/RGC protein kinase 0.0015 0.0001 0.0005
Echinococcus granulosus expressed protein 0.0384 0.1029 0.1029
Giardia lamblia G2/mitotic-specific cyclin B 0.0017 0.0007 0.0085
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0028 0.0426
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0041 0.0071 0.0071
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0137 0.0137
Echinococcus multilocularis tyrosine protein kinase Abl 0.003 0.0043 0.0043
Schistosoma mansoni tyrosine kinase 0.0033 0.0049 0.0049
Brugia malayi Patched family protein 0.0019 0.0012 0.0043
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0033 0.005 0.005
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0044 0.0082 0.1256
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0023 0.0022 0.0022
Brugia malayi Patched related family protein 4 0.0019 0.0012 0.0043
Trichomonas vaginalis hypothetical protein 0.0037 0.0061 0.0354
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0017 0.0006 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.024 0.1394
Entamoeba histolytica cysteine surface protein, putative 0.0015 0.0001 0.0006
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.003 0.0042 0.0644
Echinococcus multilocularis muscleblind protein 0.0971 0.2666 0.2666
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0033 0.0051 0.0051
Schistosoma mansoni hypothetical protein 0.013 0.0321 0.0321
Schistosoma mansoni ephrin receptor 0.0021 0.0017 0.0017
Schistosoma mansoni tyrosine kinase 0.0059 0.0123 0.0123
Brugia malayi nuclear receptor RXR 0.0016 0.0002 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0001 0.0006
Brugia malayi hypothetical protein 0.0023 0.0022 0.0084
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0028 0.0426
Onchocerca volvulus 0.003 0.0042 0.0311
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Echinococcus granulosus cyclin dependent kinase 1 0.0047 0.0089 0.0089
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.002 0.0295
Echinococcus granulosus plexin a4 0.002 0.0014 0.0014
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.002 0.0015 0.0217
Trichomonas vaginalis CMGC family protein kinase 0.007 0.0154 0.0896
Trypanosoma cruzi cdc2-related kinase 3 0.0047 0.0089 0.1359
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0013 0.0013
Toxoplasma gondii protein kinase 0.0015 0.0001 0.0008
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Plasmodium vivax patched family protein, putative 0.0019 0.0012 0.0383
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.003 0.0042 0.0042
Schistosoma mansoni serine/threonine RGC 0.0015 0.0001 0.0001
Loa Loa (eye worm) TK protein kinase 0.0015 0.0001 0.0005
Echinococcus multilocularis hemicentin 1 0.0017 0.0006 0.0006
Brugia malayi Patched related family protein 12 0.0019 0.0012 0.0043
Toxoplasma gondii AGC kinase 0.0035 0.0056 0.09
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0037 0.0037
Loa Loa (eye worm) AGC/AKT protein kinase 0.0037 0.0062 0.0233
Schistosoma mansoni tyrosine kinase 0.0059 0.0123 0.0123
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0044 0.0082 0.294
Plasmodium falciparum acyl-CoA synthetase 0.0077 0.0172 0.6188
Brugia malayi Patched family protein 0.0019 0.0012 0.0043
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0027 0.0027
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0052 0.0102 0.0102
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0456 0.123 0.123
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Plasmodium falciparum flap endonuclease 1 0.0028 0.0037 0.1321
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0059 0.0123 0.0123
Schistosoma mansoni plexin 0.0017 0.0006 0.0006
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.007 0.0154 0.0579
Schistosoma mansoni protein kinase 0.0015 0.0001 0.0001
Onchocerca volvulus 0.0025 0.0027 0.0197
Trichomonas vaginalis CMGC family protein kinase 0.007 0.0154 0.0896
Trichomonas vaginalis AGC family protein kinase 0.0017 0.0006 0.0033
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0089 0.0513
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0015 0.0001 0.0001
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0017 0.0006 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.0051 0.019
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0015 0.0001 0.0005
Echinococcus multilocularis cyclin B 0.0017 0.0007 0.0007
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0023 0.0022 0.0022
Onchocerca volvulus 0.0489 0.1322 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.002 0.0295
Loa Loa (eye worm) hypothetical protein 0.003 0.0042 0.0159
Entamoeba histolytica tyrosine kinase, putative 0.0015 0.0001 0.0006
Trypanosoma brucei rac serine-threonine kinase, putative 0.0037 0.0062 0.0953
Toxoplasma gondii hypothetical protein 0.0019 0.0012 0.0172
Echinococcus granulosus tyrosine protein kinase Src42A 0.0059 0.0123 0.0123
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0013 0.0013
Echinococcus multilocularis c src tyrosine kinase 0.003 0.0043 0.0043
Trichomonas vaginalis AGC family protein kinase 0.0115 0.0278 0.1614
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0051 0.0051
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0135 0.0334 0.1255
Loa Loa (eye worm) AUR protein kinase 0.0115 0.0278 0.1042
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0025 0.0027 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0001 0.0006
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0103 0.0245 0.0643
Trypanosoma cruzi CYC2-like cyclin, putative 0.0017 0.0007 0.0093
Echinococcus granulosus nervana 2 0.002 0.0014 0.0014
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0015 0.0001 0.0006
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0071 0.0071
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0006 0.0024
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0005
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0015 0.0001 0.0001
Brugia malayi p70 ribosomal S6 kinase beta 0.0035 0.0056 0.0212
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Brugia malayi Protein kinase domain containing protein 0.0023 0.0022 0.0084
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0139 0.0523
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0025 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0103 0.0245 0.0918
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0139 0.0139
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0194 0.05 0.05
Trichomonas vaginalis CAMK family protein kinase 0.0247 0.0646 0.3754
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.003 0.0042 0.0116
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Schistosoma mansoni hypothetical protein 0.013 0.0321 0.0321
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0158 0.0398 0.1495
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0027 0.0027
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0013 0.005
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0007
Brugia malayi Prion-like- 0.0017 0.0006 0.0024
Echinococcus multilocularis expressed protein 0.0384 0.1029 0.1029
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0037 0.0572
Trichomonas vaginalis CAMK family protein kinase 0.0247 0.0646 0.3754
Echinococcus granulosus tyrosine protein kinase Srms 0.0023 0.0022 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0025 0.0027 0.0027
Brugia malayi Cytochrome P450 family protein 0.0017 0.0006 0.0023
Echinococcus multilocularis tyrosine protein kinase HCK 0.0044 0.0081 0.0081
Schistosoma mansoni retinoic acid receptor RXR 0.0033 0.0051 0.0051
Echinococcus multilocularis Niemann Pick C1 protein 0.0314 0.0835 0.0835
Brugia malayi Raf kinase 0.0015 0.0001 0.0005
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0015 0.0001 0.0001
Loa Loa (eye worm) AMP-binding enzyme family protein 0.003 0.0042 0.0159
Loa Loa (eye worm) TK protein kinase 0.0015 0.0001 0.0005
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0015 0.0001 0.0005
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0027 0.0027
Echinococcus granulosus tyrosine protein kinase Btk29A 0.003 0.0043 0.0043
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0015 0.0001 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0001 0.0003
Onchocerca volvulus 0.0016 0.0002 0.0004
Brugia malayi CHE-14 protein 0.0135 0.0334 0.1255
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0027 0.0027
Schistosoma mansoni protein kinase 0.007 0.0154 0.0154
Echinococcus multilocularis citrate lyase subunit beta protein 0.0025 0.0028 0.0028
Brugia malayi AMP-binding enzyme family protein 0.0103 0.0245 0.0918
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0015 0.0001 0.0001
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Brugia malayi Protein kinase domain containing protein 0.0265 0.0698 0.2618
Giardia lamblia Kinase, NEK 0.0015 0.0001 0.00000011109
Trypanosoma cruzi cdc2-related kinase 1 0.0047 0.0089 0.1359
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Onchocerca volvulus 0.0033 0.0051 0.0373
Brugia malayi AMP-binding enzyme family protein 0.003 0.0042 0.0159
Trichomonas vaginalis helicase, putative 0.0028 0.0037 0.0211
Schistosoma mansoni tyrosine kinase 0.0015 0.0001 0.0001
Giardia lamblia Kinase, CMGC CDK 0.0047 0.0089 0.1353
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.003 0.0042 0.0644
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0001 0.0001
Echinococcus granulosus cyclins 0.0017 0.0007 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Entamoeba histolytica hypothetical protein 0.0041 0.0073 0.0419
Echinococcus multilocularis Immunoglobulin 0.0033 0.0052 0.0052
Brugia malayi Patched family protein 0.0019 0.0012 0.0043
Echinococcus granulosus cyclin B3 1 0.0017 0.0007 0.0007
Echinococcus multilocularis tyrosine protein kinase Srms 0.0052 0.0102 0.0102
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Trypanosoma brucei mitotic cyclin 6 0.0017 0.0007 0.0098
Brugia malayi plexin A 0.002 0.0014 0.0053
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0033 0.0051 0.0051
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0005
Trypanosoma cruzi cyclin, putative 0.0017 0.0007 0.0093
Echinococcus multilocularis cpg binding protein 0.0131 0.0323 0.0323
Brugia malayi CXXC zinc finger family protein 0.0124 0.0304 0.1139
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0027
Brugia malayi Patched related family protein 10 0.0019 0.0012 0.0043
Trypanosoma cruzi protein kinase, putative 0.0015 0.0001 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0103 0.0245 0.0679
Trypanosoma cruzi cdc2-related kinase 3 0.0047 0.0089 0.1359
Trichomonas vaginalis TKL family protein kinase 0.0015 0.0001 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0037 0.0211
Entamoeba histolytica serine/threonine kinase, putative 0.0015 0.0001 0.0006
Onchocerca volvulus Protein ultraspiracle homolog 0.0033 0.0051 0.0373
Brugia malayi hypothetical protein 0.0774 0.2116 0.7938
Brugia malayi Peroxidasin 0.0017 0.0006 0.0024
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0027 0.0027
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0023 0.0023 0.0023
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0071 0.1087
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0044 0.0082 0.0082
Onchocerca volvulus 0.0019 0.0012 0.0077
Toxoplasma gondii protein kinase domain-containing protein 0.0015 0.0001 0.0008
Echinococcus granulosus Glutaredoxin protein 5 0.002 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0043
Echinococcus granulosus cyclin dependent kinase 0.0047 0.0089 0.0089
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0044 0.0082 0.0309
Echinococcus granulosus lachesin 0.0017 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0007
Loa Loa (eye worm) TK/RYK protein kinase 0.0015 0.0001 0.0005
Echinococcus granulosus activin receptor type 0.002 0.0015 0.0015
Onchocerca volvulus 0.0025 0.0027 0.0197
Echinococcus multilocularis lachesin 0.0017 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.005
Entamoeba histolytica tyrosin kinase, putative 0.0015 0.0001 0.0006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0022 0.0082
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0006
Echinococcus granulosus expressed conserved protein 0.0295 0.0782 0.0782
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.0022 0.0082
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0064 0.0137 0.0513
Schistosoma mansoni serine/threonine-protein kinase 0.0027 0.0033 0.0033
Echinococcus multilocularis roundabout 2 0.0023 0.0022 0.0022
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0139 0.0139
Mycobacterium ulcerans acyl-CoA synthetase 0.003 0.0042 0.0098
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0013 0.0013
Brugia malayi protein-tyrosine kinase 0.0052 0.0102 0.0383
Echinococcus granulosus tyrosine protein kinase Fyn 0.0059 0.0123 0.0123
Brugia malayi steroid hormone receptor 0.0033 0.0051 0.019
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.003 0.0042 0.0098
Echinococcus granulosus FTZ F1 alpha 0.0033 0.0051 0.0051
Echinococcus multilocularis tyrosine kinase 0.0023 0.0022 0.0022
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0027 0.0027
Echinococcus multilocularis peroxidasin 0.0017 0.0006 0.0006
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0013 0.0013
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0015 0.0001 0.0005
Entamoeba histolytica protein kinase domain containing protein 0.0015 0.0001 0.0006
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.043 0.1158 0.4342

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) 67.531 uM PubChem BioAssay. Counterscreen for agonists of the daf-12 abnormal Dauer Formation: Luminescence-based cell-based screening assay to identify agonists of the Liver-X-Receptor (LXR).. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 2.2387 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 4.4668 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 9.285 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (binding) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 89.1251 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.