Detailed information for compound 1488333

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 234.291 | Formula: C14H18O3
  • H donors: 1 H acceptors: 3 LogP: 2.88 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(CC1=C(O)C(=O)C2=C(C1=O)CCCC2)C
  • InChi: 1S/C14H18O3/c1-8(2)7-11-12(15)9-5-3-4-6-10(9)13(16)14(11)17/h8,17H,3-7H2,1-2H3
  • InChiKey: OIFDRMACNGIEQC-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0143 0.0728
Echinococcus multilocularis phosphoserine phosphatase 0.0005 0.0009 0.0033
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0005 0.0009 0.0033
Brugia malayi SH2 domain containing protein 0.0006 0.0012 0.0005
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0036 0.0242 0.1033
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0126 0.0639
Schistosoma mansoni signal transduction protein lnk-related 0.0006 0.0012 0.005
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0018 0.0106 0.0359
Loa Loa (eye worm) acetylcholinesterase 1 0.0137 0.1001 0.4402
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0039 0.026 0.1338
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0006 0.0012 0.005
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0018 0.0106 0.0535
Echinococcus granulosus GPCR family 2 0.0021 0.0129 0.0654
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0126 0.0639
Onchocerca volvulus 0.0006 0.0012 0.0003
Leishmania major proteasome beta 3 subunit, putative 0.0018 0.0106 0.0359
Toxoplasma gondii peptidase, T1 family protein 0.0018 0.0106 0.0359
Schistosoma mansoni thyroid hormone receptor 0.0115 0.0838 0.4335
Echinococcus granulosus SH2 domain containing protein 7 0.0006 0.0012 0.005
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0072 0.0511 0.7632
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0006 0.0012 0.005
Echinococcus multilocularis phosphoserine phosphatase 0.0005 0.0009 0.0033
Echinococcus multilocularis acetylcholinesterase 0.0137 0.1001 0.5184
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0018 0.0106 0.0359
Leishmania major proteasome beta 2 subunit, putative 0.0045 0.0305 0.1097
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0018 0.0106 0.0359
Echinococcus multilocularis phosphoserine phosphatase 0.0005 0.0009 0.0033
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0006 0.0012 0.005
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0018 0.0106 0.0359
Entamoeba histolytica SH2 domain containing protein 0.0006 0.0012 0.005
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0072 0.0511 0.1862
Echinococcus granulosus proteasome subunit beta type 7 0.0018 0.0106 0.0535
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0023 0.0143 0.0728
Echinococcus multilocularis proteasome (prosome, macropain) 0.0093 0.0667 0.3451
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0005 0.0009 0.0033
Onchocerca volvulus 0.0006 0.0012 0.0003
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0126 0.0639
Trypanosoma cruzi serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.004 0.0274 0.0982
Echinococcus granulosus tyrosine protein kinase Src64B 0.0006 0.0012 0.005
Echinococcus multilocularis tensin 0.0006 0.0012 0.005
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0014
Onchocerca volvulus 0.0006 0.0012 0.0003
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0018 0.0106 0.0535
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0018 0.0106 0.0535
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0018 0.0106 0.1471
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0015 0.0082 0.0272
Brugia malayi nuclear hormone receptor 0.0021 0.0126 0.0161
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0018 0.0106 0.1471
Plasmodium vivax proteasome subunit beta type-3, putative 0.0018 0.0106 0.0359
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0042 0.0149
Plasmodium vivax telomerase reverse transcriptase, putative 0.0363 0.2708 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0042 0.0207
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0018 0.0106 0.043
Echinococcus granulosus expressed conserved protein 0.0006 0.0012 0.005
Echinococcus granulosus c src tyrosine kinase 0.0006 0.0012 0.005
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0018 0.0106 0.0359
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0126 0.0518
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0036 0.0242 0.0892
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0018 0.0106 0.0359
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0018 0.0106 0.0535
Brugia malayi Carboxylesterase family protein 0.0137 0.1001 0.1369
Echinococcus multilocularis BC026374 protein (S09 family) 0.0023 0.0143 0.0728
Trypanosoma brucei protein phosphatase 2B, putative 0.004 0.0274 0.1011
Echinococcus multilocularis SH2 domain containing protein 7 0.0006 0.0012 0.005
Brugia malayi Proteasome A-type and B-type family protein 0.0093 0.0667 0.0908
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0126 0.0161
Schistosoma mansoni hypothetical protein 0.0021 0.0129 0.0654
Loa Loa (eye worm) hypothetical protein 0.004 0.0274 0.1176
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0219 0.162 0.7146
Brugia malayi SH2 domain containing protein 0.0006 0.0012 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0126 0.0518
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0018 0.0106 0.1471
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0006 0.0015 0.0087
Echinococcus multilocularis acetylcholinesterase 0.0137 0.1001 0.5184
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0045 0.0305 0.4495
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0126 0.0161
Brugia malayi cytokine inducible SH2-containing protein 5 0.0006 0.0012 0.0005
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0018 0.0106 0.0359
Brugia malayi Protein kinase domain containing protein 0.0006 0.0012 0.0005
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0006 0.0012 0.005
Echinococcus granulosus proteasome subunit alpha type 2 0.0018 0.0106 0.0535
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0018 0.0106 0.039
Brugia malayi Variant SH3 domain containing protein 0.0006 0.0012 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0126 0.0518
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0094 0.0681 0.3519
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0042 0.0207
Loa Loa (eye worm) hypothetical protein 0.0011 0.0051 0.0189
Schistosoma mansoni BC026374 protein (S09 family) 0.0023 0.0143 0.0728
Brugia malayi proteasome subunit alpha type 2 0.0018 0.0106 0.0134
Brugia malayi Protein kinase domain containing protein 0.0006 0.0012 0.0005
Loa Loa (eye worm) hypothetical protein 0.0023 0.0143 0.0594
Loa Loa (eye worm) hypothetical protein 0.0023 0.0143 0.0594
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0072 0.0511 0.7632
Brugia malayi proteasome subunit alpha type 6 0.0018 0.0106 0.0134
Echinococcus multilocularis SH2 motif 0.0006 0.0012 0.005
Entamoeba histolytica hypothetical protein 0.0017 0.0094 0.1289
Onchocerca volvulus Notchless protein homolog 0.0018 0.0106 0.0097
Echinococcus granulosus Proteasome subunit alpha type 7 0.0018 0.0106 0.0535
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0045 0.0305 0.1569
Echinococcus granulosus tyrosine protein kinase Src42A 0.0006 0.0012 0.005
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0014
Mycobacterium ulcerans carboxylesterase, LipT 0.0023 0.0143 0.2035
Loa Loa (eye worm) hypothetical protein 0.001 0.0042 0.0149
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0018 0.0106 0.0359
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0018 0.0106 0.0359
Brugia malayi Proteasome subunit alpha type 7-1 0.0018 0.0106 0.0134
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0018 0.0106 0.039
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0014
Schistosoma mansoni cation-transporting ATPase 0.0005 0.0009 0.0033
Schistosoma mansoni eyes absent homolog 0.0056 0.0391 0.2015
Brugia malayi SH2 domain containing protein 0.0006 0.0012 0.0005
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.004 0.0274 0.1409
Echinococcus multilocularis dnaJ subfamily B 0.026 0.1929 1
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0.0106 0.1471
Schistosoma mansoni protein phosphatase-2b 0.004 0.0274 0.1409
Schistosoma mansoni tyrosine kinase 0.0006 0.0012 0.005
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0012 0.0014
Brugia malayi Importin beta-1 subunit 0.002 0.0123 0.0157
Loa Loa (eye worm) hypothetical protein 0.0023 0.0143 0.0594
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0018 0.0106 0.039
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0006 0.0012 0.005
Loa Loa (eye worm) histone methyltransferase 0.0006 0.0011 0.0009
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0029 0.0188 0.0961
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0006 0.0012 0.0014
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0018 0.0106 0.0359
Echinococcus granulosus tensin 0.0006 0.0012 0.005
Schistosoma mansoni nck2/grb4 0.0006 0.0012 0.005
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0005 0.0009 0.0033
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0018 0.0106 0.0535
Brugia malayi ecdysteroid receptor 0.0021 0.0126 0.0161
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0014
Brugia malayi ecdysone receptor 0.001 0.0042 0.0046
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0045 0.0305 0.1569
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0093 0.0667 1
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0042 0.0207
Loa Loa (eye worm) hypothetical protein 0.0137 0.1001 0.4402
Schistosoma mansoni hypothetical protein 0.0006 0.0012 0.005
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0018 0.0106 0.0535
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0018 0.0106 0.0535
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0018 0.0106 0.5
Echinococcus granulosus tyrosine protein kinase ABL1 0.0006 0.0012 0.005
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0029 0.0188 0.0793
Brugia malayi steroid hormone receptor 0.0021 0.0126 0.0161
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0018 0.0106 0.1471
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0018 0.0106 0.0359
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0018 0.0106 0.043
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0018 0.0106 0.0359
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0018 0.0106 0.0535
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0018 0.0106 0.1471
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0006 0.0011 0.0044
Brugia malayi protein-tyrosine kinase 0.0006 0.0012 0.0005
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0051 0.0254
Brugia malayi Protein kinase domain containing protein 0.0006 0.0012 0.0005
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0.0106 0.1471
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0006 0.0012 0.005
Plasmodium falciparum telomerase reverse transcriptase 0.0363 0.2708 1
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.004 0.0274 0.1409
Leishmania major proteasome beta-1 subunit, putative 0.0018 0.0106 0.0359
Brugia malayi hypothetical protein 0.0011 0.0051 0.0059
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0126 0.0161
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0051 0.0059
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0018 0.0106 0.0535
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0018 0.0106 0.0359
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0006 0.0012 0.005
Brugia malayi Carboxylesterase family protein 0.0023 0.0143 0.0185
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0051 0.0059
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0015 0.0082 0.0272
Echinococcus multilocularis cation transporting atpase worm 0.0005 0.0009 0.0033
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0006 0.0012 0.005
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0036 0.0242 0.0863
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0093 0.0667 0.244
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0018 0.0106 0.0359
Onchocerca volvulus 0.0018 0.0106 0.0097
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0018 0.0106 0.0359
Schistosoma mansoni SH2A 0.0006 0.0012 0.005
Brugia malayi Serine/threonine protein phosphatase 2B catalytic subunit 2 0.004 0.0274 0.0366
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0018 0.0106 0.0359
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0067 0.0475 0.0643
Echinococcus granulosus growth factor receptor bound protein 2 0.0006 0.0012 0.005
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0018 0.0106 0.0359
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0126 0.0639
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0126 0.0639
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0126 0.0161
Schistosoma mansoni cpg binding protein 0.0018 0.0106 0.0537
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0018 0.0106 0.0535
Echinococcus multilocularis cation transporting ATPase 13A3 0.0005 0.0009 0.0033
Loa Loa (eye worm) hypothetical protein 0.001 0.0042 0.0149
Echinococcus granulosus N chimaerin 0.0006 0.0012 0.005
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0006 0.0012 0.005
Brugia malayi RNA, U transporter 1 0.0058 0.0408 0.0551
Echinococcus granulosus tyrosine protein kinase Lyn 0.0006 0.0015 0.0063
Loa Loa (eye worm) hypothetical protein 0.0021 0.0129 0.0531
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0126 0.0518
Schistosoma mansoni hypothetical protein 0.0021 0.0129 0.0654
Giardia lamblia Proteasome subunit beta type 2 0.0045 0.0305 0.1097
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0014
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0006 0.0012 0.005
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0093 0.0667 1
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0093 0.0667 0.2921
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0042 0.0207
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0126 0.0518
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0051 0.0254
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0006 0.0011 0.0044
Echinococcus granulosus carboxylesterase 5A 0.0137 0.1001 0.5184
Mycobacterium tuberculosis Carboxylesterase LipT 0.0023 0.0143 0.2035
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0018 0.0106 0.1471
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0018 0.0106 0.039
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0012 0.0014
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0018 0.0106 0.1471
Schistosoma mansoni hypothetical protein 0.0021 0.0129 0.0654
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0018 0.0106 0.0359
Echinococcus granulosus cpg binding protein 0.0019 0.0114 0.0578
Echinococcus multilocularis phosphoserine phosphatase 0.0005 0.0009 0.0033
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.004 0.0274 0.4025
Loa Loa (eye worm) hypothetical protein 0.001 0.0042 0.0149
Loa Loa (eye worm) hypothetical protein 0.0056 0.0391 0.1694
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0021 0.0129 0.0654
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0018 0.0106 0.0535
Plasmodium falciparum serine/threonine protein phosphatase 2B catalytic subunit A 0.004 0.0274 0.0982
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0126 0.0639
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0018 0.0106 0.0359
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0072 0.0511 0.2642
Treponema pallidum hypothetical protein 0.0005 0.0009 0.5
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0015 0.0082 0.0272
Echinococcus granulosus suppressor of cytokine signaling 6 0.0006 0.0012 0.005
Loa Loa (eye worm) hypothetical protein 0.001 0.0042 0.0149
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0093 0.0667 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0051 0.0254
Loa Loa (eye worm) hypothetical protein 0.002 0.0123 0.0506
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0143 0.2035
Schistosoma mansoni ran 0.0015 0.0082 0.0413
Toxoplasma gondii proteasome subunit beta type, putative 0.0093 0.0667 0.244
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.004 0.0274 0.4025
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0006 0.0012 0.005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0126 0.0639
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0018 0.0106 0.0535
Onchocerca volvulus 0.0006 0.0012 0.0003
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0018 0.0106 0.0359
Echinococcus granulosus neuroligin 0.0023 0.0143 0.0728
Echinococcus granulosus tyrosine protein kinase Srms 0.0006 0.0012 0.005
Loa Loa (eye worm) proteasome subunit beta type 3 0.0018 0.0106 0.043
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0018 0.0106 0.039
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0018 0.0106 0.0535
Schistosoma mansoni cation-transporting atpase worm 0.0005 0.0009 0.0033
Echinococcus granulosus GTP binding nuclear protein Ran 0.0015 0.0082 0.0413
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0005 0.0009 0.0032
Brugia malayi 20S proteasome alpha5 subunit 0.0018 0.0106 0.0134
Schistosoma mansoni copper ABC transporter ATPase 0.0005 0.0009 0.0033
Plasmodium vivax proteasome subunit beta type-6, putative 0.0018 0.0106 0.0359
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0012 0.0014
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0018 0.0106 0.039
Schistosoma mansoni neuroligin 3 (S09 family) 0.0023 0.0143 0.0728
Loa Loa (eye worm) hypothetical protein 0.0021 0.0126 0.0518
Schistosoma mansoni importin beta-1 0.002 0.0123 0.0625
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0042 0.0207
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0018 0.0106 0.0359
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0036 0.0242 0.0863
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0006 0.0012 0.0014
Echinococcus granulosus mitogen activated protein kinase 3 0.0036 0.0242 0.1241
Echinococcus granulosus hypothetical protein 0.0006 0.0012 0.005
Loa Loa (eye worm) carboxylesterase 0.0023 0.0143 0.0594
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0005 0.0009 0.0032
Treponema pallidum cation-transporting ATPase, P-type 0.0005 0.0009 0.5
Brugia malayi Proteasome A-type and B-type family protein 0.0018 0.0106 0.0134
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0006 0.0012 0.005
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0018 0.0106 0.0359
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0006 0.0012 0.005
Trypanosoma cruzi 20S proteasome subunit 0.0045 0.0305 0.1097
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0006 0.0012 0.005
Brugia malayi tailless protein 0.001 0.0042 0.0046
Loa Loa (eye worm) hypothetical protein 0.0056 0.0391 0.1694
Echinococcus granulosus cation transporting ATPase 13A1 0.0005 0.0009 0.0033
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0018 0.0106 0.0359
Brugia malayi proteasome subunit alpha type 1 0.0018 0.0106 0.0134
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0072 0.0511 0.1862
Brugia malayi Nuclear hormone receptor E75 0.001 0.0042 0.0046
Loa Loa (eye worm) hypothetical protein 0.0011 0.0051 0.0189
Schistosoma mansoni hypothetical protein 0.0046 0.0314 0.1619
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0126 0.0639
Echinococcus granulosus proteasome subunit beta type 6 0.0018 0.0106 0.0535
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0018 0.0106 0.0359
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0018 0.0106 0.039
Echinococcus multilocularis NCK adaptor protein 0.0006 0.0012 0.005
Onchocerca volvulus 0.0023 0.0143 0.0134
Toxoplasma gondii histone lysine methyltransferase SET1 0.0035 0.0229 0.0816
Schistosoma mansoni tyrosine kinase 0.0006 0.0012 0.005
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0126 0.0639
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0018 0.0106 0.1471
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0014
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0006 0.0012 0.005
Loa Loa (eye worm) PAS-3 protein 0.0018 0.0106 0.043
Giardia lamblia Proteasome subunit beta type 1 0.0072 0.0511 0.1862
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0126 0.0639
Brugia malayi Calcitonin receptor-like protein seb-1 0.0067 0.0475 0.0643
Echinococcus multilocularis cation transporting ATPase 13A1 0.0005 0.0009 0.0033
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0006 0.0012 0.0003
Brugia malayi SH2 domain containing protein 0.0006 0.0012 0.0005
Echinococcus multilocularis mitogen activated protein kinase 3 0.0036 0.0242 0.1241
Echinococcus granulosus tyrosine protein kinase Src42A 0.0006 0.0012 0.005
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0015 0.0082 0.0325
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0018 0.0106 0.0359
Schistosoma mansoni adapter molecule crk 0.0006 0.0012 0.005
Toxoplasma gondii proteasome subunit alpha type, putative 0.0018 0.0106 0.0359
Echinococcus granulosus tyrosine protein kinase Fyn 0.0006 0.0012 0.005
Schistosoma mansoni phosphoserine phosphatase 0.0005 0.0009 0.0033
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0006 0.0012 0.0014
Echinococcus granulosus proteasome prosome macropain 0.0093 0.0667 0.3451
Loa Loa (eye worm) hypothetical protein 0.0011 0.0051 0.0189
Loa Loa (eye worm) hypothetical protein 0.0046 0.0314 0.1356
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0021 0.0129 0.0654
Echinococcus granulosus dnaJ subfamily B 0.026 0.1929 1
Onchocerca volvulus 0.0006 0.0012 0.0003
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0045 0.0305 0.4495
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0018 0.0106 0.0535
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0018 0.0106 0.0359
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0363 0.2708 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0051 0.0189
Trypanosoma brucei importin beta-1 subunit, putative 0.002 0.0123 0.0454
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0094 0.0681 0.3519
Leishmania major serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.004 0.0274 0.0982
Loa Loa (eye worm) hypothetical protein 0.0021 0.0126 0.0518
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0017 0.0094 0.1289
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0126 0.0518
Brugia malayi proteasome subunit beta type 1 0.0072 0.0511 0.0693
Brugia malayi Carboxylesterase family protein 0.0023 0.0143 0.0185
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0045 0.0305 0.1097
Leishmania major proteasome beta 5 subunit, putative 0.0093 0.0667 0.244
Brugia malayi CXXC zinc finger family protein 0.0018 0.0106 0.0134
Plasmodium vivax proteasome subunit beta type-2, putative 0.0045 0.0305 0.1097
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0143 0.0728
Leishmania major GTP-binding protein, putative 0.0015 0.0082 0.0272
Brugia malayi hypothetical protein 0.0006 0.0012 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0126 0.0518
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0018 0.0106 0.0359
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0242 0.3535
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0072 0.0511 0.2642
Echinococcus multilocularis snurportin 1 0.0219 0.162 0.8394
Brugia malayi Protein kinase domain containing protein 0.0006 0.0012 0.0005
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0015 0.0082 0.0272
Echinococcus granulosus importin subunit beta 1 0.002 0.0123 0.0625
Echinococcus multilocularis mitogen activated protein kinase 0.0036 0.0242 0.1241
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0045 0.0305 0.1097
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0018 0.0106 0.0535
Loa Loa (eye worm) hypothetical protein 0.001 0.0042 0.0149
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0018 0.0106 0.0535
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0126 0.0639
Brugia malayi STAT protein, DNA binding domain containing protein 0.0304 0.2263 0.3109
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0042 0.0207
Leishmania major importin beta-1 subunit, putative 0.0017 0.0094 0.0315
Trypanosoma brucei proteasome beta 6 subunit 0.0072 0.0511 0.1888
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0042 0.0207
Brugia malayi hypothetical protein 0.0011 0.0051 0.0059
Echinococcus multilocularis carboxylesterase 5A 0.0137 0.1001 0.5184
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0006 0.0012 0.005
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0126 0.0161
Brugia malayi SH2 domain containing protein 0.0006 0.0012 0.0005
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0021 0.0129 0.0654
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0011 0.0051 0.0189
Brugia malayi Sex muscle abnormal protein 5 0.0006 0.0012 0.0005
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0051 0.0254
Echinococcus multilocularis tyrosine protein kinase Abl 0.0006 0.0012 0.005
Loa Loa (eye worm) hypothetical protein 0.0023 0.0143 0.0594
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0029 0.0188 0.0961
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0072 0.0511 0.1862
Loa Loa (eye worm) SH2 domain-containing protein 0.0006 0.0012 0.0014
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0045 0.0305 0.4495
Giardia lamblia 20S proteasome alpha subunit 5 0.0018 0.0106 0.0359
Brugia malayi Nuclear hormone receptor E75 0.001 0.0042 0.0046
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0042 0.0207
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0126 0.0639
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0006 0.0012 0.005
Plasmodium vivax serine/threonine protein phosphatase 2B catalytic subunit A, putative 0.004 0.0274 0.0982
Toxoplasma gondii proteasome beta subunit 0.0018 0.0106 0.0359
Toxoplasma gondii proteasome subunit 0.0018 0.0106 0.0359
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0018 0.0106 0.0359
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0018 0.0106 0.043
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.0042 0.0207
Plasmodium falciparum proteasome subunit beta type-5 0.0093 0.0667 0.244
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0126 0.0639
Brugia malayi Carboxylesterase family protein 0.0023 0.0143 0.0185
Brugia malayi proteasome subunit alpha type 3 0.0018 0.0106 0.0134
Brugia malayi hypothetical protein 0.0006 0.0012 0.0005
Schistosoma mansoni hypothetical protein 0.0219 0.162 0.8394
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0126 0.0518
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0018 0.0106 0.1471
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0006 0.0012 0.005
Loa Loa (eye worm) TK protein kinase 0.0006 0.0012 0.0014
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0036 0.0242 0.0863
Loa Loa (eye worm) hypothetical protein 0.0023 0.0143 0.0594
Brugia malayi nuclear receptor NHR-88 0.001 0.0042 0.0046
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0.0042 0.0046
Onchocerca volvulus 0.0006 0.0012 0.0003
Echinococcus granulosus SH2 motif 0.0006 0.0012 0.005
Loa Loa (eye worm) hypothetical protein 0.0067 0.0475 0.2067
Brugia malayi SH2 domain containing protein 0.0006 0.0012 0.0005
Brugia malayi latrophilin 2 splice variant baaae 0.0046 0.0314 0.0422
Brugia malayi proteasome subunit beta type 2 0.0045 0.0305 0.0408
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0018 0.0106 0.0535
Loa Loa (eye worm) hypothetical protein 0.001 0.0042 0.0149
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0018 0.0106 0.0359
Onchocerca volvulus 0.0006 0.0012 0.0003
Brugia malayi Protein kinase domain containing protein 0.0006 0.0012 0.0005
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0018 0.0106 0.1471
Leishmania major proteasome alpha 3 subunit, putative 0.0018 0.0106 0.0359
Echinococcus granulosus proteasome subunit alpha type 6 0.0018 0.0106 0.0535
Trypanosoma cruzi importin beta-1 subunit, putative 0.0017 0.0094 0.0315
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0012 0.0014
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0018 0.0106 0.0535
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0018 0.0106 0.0359
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0006 0.0012 0.005
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0018 0.0106 0.0359
Trypanosoma brucei proteasome alpha 7 subunit 0.0018 0.0106 0.039
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0018 0.0106 0.043
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.0042 0.0207
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0.0106 0.1471
Loa Loa (eye worm) SH2 domain-containing protein 0.0006 0.0012 0.0014
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0042 0.0207
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0018 0.0106 0.0359
Brugia malayi hypothetical protein 0.001 0.0042 0.0046
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0.0106 0.1471
Plasmodium falciparum importin beta, putative 0.002 0.0123 0.0423
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0126 0.0639
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0018 0.0106 0.1471
Brugia malayi Variant SH3 domain containing protein 0.0006 0.0012 0.0005
Brugia malayi hypothetical protein 0.001 0.0042 0.0046
Trypanosoma brucei proteasome beta 7 subunit 0.0018 0.0106 0.039
Brugia malayi nuclear hormone receptor 0.001 0.0042 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0126 0.0161
Loa Loa (eye worm) hypothetical protein 0.001 0.0042 0.0149
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0018 0.0106 0.1471
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0012 0.0014
Entamoeba histolytica protein kinase, putative 0.0006 0.0015 0.0087
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0.0106 0.1471
Echinococcus granulosus SHC transforming protein 3 0.0006 0.0012 0.005
Loa Loa (eye worm) hypothetical protein 0.001 0.0042 0.0149
Schistosoma mansoni growth factor receptor-bound protein 0.0006 0.0012 0.005
Brugia malayi tRNA modification GTPase TrmE family protein 0.0006 0.0012 0.0005
Schistosoma mansoni hypothetical protein 0.0006 0.0012 0.005
Trichomonas vaginalis spcc417.12 protein, putative 0.0023 0.0143 0.2035
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0126 0.0639
Echinococcus granulosus snurportin 1 0.0219 0.162 0.8394
Loa Loa (eye worm) hypothetical protein 0.001 0.0042 0.0149
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0.0106 0.1471
Onchocerca volvulus 0.0006 0.0012 0.0003
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0006 0.0012 0.005
Loa Loa (eye worm) hypothetical protein 0.0023 0.0143 0.0594
Onchocerca volvulus 0.0023 0.0143 0.0134
Echinococcus multilocularis tyrosine kinase 0.0006 0.0012 0.005
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0042 0.0034
Schistosoma mansoni atpase class VI type 11c 0.0005 0.0009 0.0033
Echinococcus multilocularis SH2 motif 0.0006 0.0012 0.005
Brugia malayi hypothetical protein 0.0023 0.0143 0.0185
Brugia malayi nuclear receptor RXR 0.001 0.0042 0.0046
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0005 0.0009 0.0033
Brugia malayi RhoGAP domain containing protein 0.0006 0.0012 0.0005
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0018 0.0106 0.0359
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0006 0.0012 0.0014
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0005 0.0009 0.0033
Chlamydia trachomatis metal transport ATPase 0.0005 0.0009 0.5
Giardia lamblia Telomerase catalytic subunit 0.0363 0.2708 1
Echinococcus granulosus cation transporting atpase worm 0.0005 0.0009 0.0033
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0018 0.0106 0.0359
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0005 0.0009 0.0033
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0005 0.0009 0.0033
Echinococcus multilocularis tensin 0.0006 0.0012 0.005
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.004 0.0274 0.0982
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0018 0.0106 0.0359
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0018 0.0106 0.0535
Loa Loa (eye worm) hypothetical protein 0.001 0.0042 0.0149
Mycobacterium ulcerans proteasome PrcB 0.0093 0.0667 1
Echinococcus granulosus acetylcholinesterase 0.0137 0.1001 0.5184
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0045 0.0305 0.1569
Schistosoma mansoni tensin 0.0006 0.0012 0.005
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0018 0.0106 0.0359
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0018 0.0106 0.1471
Echinococcus multilocularis tyrosine protein kinase shark 0.0006 0.0012 0.005
Brugia malayi Variant SH3 domain containing protein 0.0006 0.0012 0.0005
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0005 0.0009 0.0033
Echinococcus multilocularis 0.0006 0.0012 0.005
Onchocerca volvulus 0.001 0.0042 0.0034
Onchocerca volvulus 0.0023 0.0143 0.0134
Echinococcus multilocularis importin subunit beta 1 0.002 0.0123 0.0625
Brugia malayi MAP kinase sur-1 0.0036 0.0242 0.0321
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0006 0.0012 0.005
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0126 0.0639
Brugia malayi proteasome subunit alpha type 4 0.0018 0.0106 0.0134
Trichomonas vaginalis importin beta-1, putative 0.0017 0.0094 0.1289
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0018 0.0106 0.1471
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.004 0.0274 0.4025
Schistosoma mansoni tyrosine kinase 0.0006 0.0012 0.005
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0006 0.0012 0.005
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0018 0.0106 0.0535
Schistosoma mansoni gliotactin 0.0023 0.0143 0.0728
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0012 0.0014
Echinococcus granulosus Proteasome subunit alpha beta 0.0018 0.0106 0.0535
Loa Loa (eye worm) SRC-1 0.0006 0.0012 0.0014
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0006 0.0012 0.005
Schistosoma mansoni tyrosine kinase 0.0006 0.0012 0.005
Giardia lamblia 20S proteasome alpha subunit 1 0.0018 0.0106 0.0359
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0023 0.0143 0.0594
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.001 0.0042 0.0149
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0018 0.0106 0.0359
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0015 0.0082 0.0272
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0093 0.0672 0.3473
Loa Loa (eye worm) proteasome subunit beta type 2 0.0045 0.0305 0.1313
Loa Loa (eye worm) hypothetical protein 0.0021 0.0126 0.0518
Loa Loa (eye worm) CXXC zinc finger family protein 0.0018 0.0106 0.0431
Echinococcus granulosus tyrosine protein kinase Blk 0.0006 0.0012 0.005
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.004 0.0274 0.4025
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0029 0.0188 0.0961
Trypanosoma brucei cation-transporting ATPase, putative 0.0005 0.0009 0.0032
Echinococcus granulosus subfamily T1A non peptidase ue 0.0018 0.0106 0.0535
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0018 0.0106 0.0359
Brugia malayi Proteasome A-type and B-type family protein 0.0018 0.0106 0.0134
Schistosoma mansoni suppressor of cytokine signaling 0.0006 0.0012 0.005
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0126 0.0639
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0036 0.0242 0.0863
Toxoplasma gondii proteasome subunit alpha1, putative 0.0018 0.0106 0.0359
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0014
Echinococcus granulosus mitogen activated protein kinase 0.0036 0.0242 0.1241
Schistosoma mansoni shc transforming protein 0.0006 0.0012 0.005
Loa Loa (eye worm) hypothetical protein 0.001 0.0042 0.0149
Echinococcus granulosus para nitrobenzyl esterase 0.0023 0.0143 0.0728
Echinococcus multilocularis proteasome subunit alpha type 6 0.0018 0.0106 0.0535
Schistosoma mansoni acetylcholinesterase 0.0023 0.0143 0.0728
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0029 0.0188 0.0961
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0126 0.0639
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0126 0.0161
Brugia malayi Proteasome A-type and B-type family protein 0.0018 0.0106 0.0134
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0051 0.0189
Echinococcus multilocularis para nitrobenzyl esterase 0.0023 0.0143 0.0728
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0018 0.0106 0.0359
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0012 0.0014
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0018 0.0106 0.0535
Echinococcus multilocularis proteasome subunit alpha type 2 0.0018 0.0106 0.0535
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0018 0.0106 0.0359
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0.0042 0.0046
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0242 0.1241
Plasmodium vivax proteasome subunit beta type-4, putative 0.0018 0.0106 0.0359
Echinococcus granulosus tyrosine protein kinase shark 0.0006 0.0012 0.005
Loa Loa (eye worm) proteasome subunit beta type 1 0.0072 0.0511 0.223
Echinococcus multilocularis SH2 motif 0.0006 0.0012 0.005
Echinococcus multilocularis copper transporting ATPase 1 0.0005 0.0009 0.0033
Schistosoma mansoni zinc finger protein 0.001 0.0042 0.0207
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0018 0.0106 0.0359
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0018 0.0106 0.1471
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0018 0.0106 0.0535
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0018 0.0106 0.043
Brugia malayi orphan nuclear receptor NR2E1 0.001 0.0042 0.0046
Brugia malayi nuclear receptor NHR-67 0.001 0.0042 0.0046
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.004 0.0274 0.1409
Schistosoma mansoni tyrosine kinase 0.0006 0.0012 0.005
Brugia malayi SH2 domain containing protein 0.0006 0.0012 0.0005
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0042 0.0207
Plasmodium vivax proteasome subunit beta type-5, putative 0.0093 0.0667 0.244
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0126 0.0161
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0126 0.0161
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0242 0.3535
Leishmania major proteasome alpha 7 subunit, putative 0.0018 0.0106 0.0359
Loa Loa (eye worm) STAT protein 0.0304 0.2263 1
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0045 0.0305 0.1125
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0021 0.0129 0.0654
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0018 0.0106 0.1471
Brugia malayi Tyrosine-protein kinase abl-1 0.0006 0.0012 0.0005
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0005 0.0009 0.0032
Brugia malayi Carboxylesterase family protein 0.0137 0.1001 0.1369
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0018 0.0106 0.1471
Loa Loa (eye worm) SH2 domain-containing protein 0.0006 0.0012 0.0014
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0018 0.0106 0.0359
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0018 0.0106 0.0359
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0.0042 0.0046
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0042 0.0207
Giardia lamblia Proteasome subunit beta type 3 0.0018 0.0106 0.0359
Mycobacterium ulcerans proteasome PrcA 0.0018 0.0106 0.1471
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0018 0.0106 0.0359
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0005 0.0009 0.0033
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0006 0.0012 0.005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0029 0.0188 0.0961
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0018 0.0106 0.0359
Schistosoma mansoni thyroid hormone receptor 0.0115 0.0838 0.4335
Brugia malayi SH2 domain containing protein 0.0006 0.0012 0.0005
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0006 0.0012 0.005
Entamoeba histolytica Ran family GTPase 0.0015 0.0082 0.1113
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0015 0.0082 0.0303
Echinococcus multilocularis growth factor receptor bound protein 2 0.0006 0.0012 0.005
Schistosoma mansoni GTPase activating protein 0.0006 0.0012 0.005
Echinococcus granulosus SH2 motif 0.0006 0.0012 0.005
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0.0106 0.1471
Loa Loa (eye worm) hypothetical protein 0.0021 0.0126 0.0518
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0014
Brugia malayi nuclear receptor NHR-88 0.0021 0.0126 0.0161
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0006 0.0012 0.005
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0018 0.0106 0.1471
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0126 0.0161
Brugia malayi proteasome subunit beta type 3 0.0018 0.0106 0.0134
Brugia malayi SRC-1 0.0006 0.0012 0.0005
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0126 0.0639
Schistosoma mansoni tyrosine kinase 0.0006 0.0012 0.005
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0006 0.0012 0.005
Leishmania major proteasome alpha 7 subunit, putative 0.0018 0.0106 0.0359
Schistosoma mansoni cation-transporting atpase worm 0.0005 0.0009 0.0033
Brugia malayi F/Y-rich N-terminus family protein 0.0006 0.001 0.0002
Schistosoma mansoni nuclear receptor 0.001 0.0042 0.0207
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0006 0.0012 0.005
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0006 0.0012 0.005
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0006 0.0012 0.005
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.004 0.0274 0.4025
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0018 0.0106 0.039
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0006 0.0012 0.0005
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0093 0.0667 0.244
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0126 0.0518
Echinococcus multilocularis c src tyrosine kinase 0.0006 0.0012 0.005
Echinococcus multilocularis cpg binding protein 0.0019 0.0114 0.0578
Leishmania major proteasome beta 2 subunit, putative 0.0018 0.0106 0.0359
Loa Loa (eye worm) latrophilin receptor protein 2 0.0021 0.0129 0.0531
Echinococcus multilocularis tyrosine protein kinase Blk 0.0006 0.0012 0.005
Schistosoma mansoni tensin 0.0006 0.0012 0.005
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0045 0.0305 0.1569
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0093 0.0667 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0067 0.0475 0.2067
Echinococcus granulosus tyrosine protein kinase Fyn 0.0006 0.0012 0.005
Schistosoma mansoni protein phosphatase-2b 0.004 0.0274 0.1409
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0072 0.0511 0.1862
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0006 0.0012 0.005
Echinococcus granulosus cation transporting ATPase 13A3 0.0005 0.0009 0.0033
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0021 0.0129 0.0165
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0093 0.0667 0.244
Echinococcus multilocularis neuroligin 0.0023 0.0143 0.0728
Echinococcus granulosus proteasome subunit beta t family 0.0018 0.0106 0.0535
Trichomonas vaginalis ran, putative 0.0015 0.0082 0.1113
Plasmodium vivax proteasome subunit beta type-1, putative 0.0072 0.0511 0.1862
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0018 0.0106 0.1471
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0126 0.0161
Brugia malayi Tensin 0.0006 0.0012 0.0005
Loa Loa (eye worm) DR-78 0.001 0.0042 0.0149
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0126 0.0639
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0126 0.0161
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0018 0.0106 0.1471
Loa Loa (eye worm) hypothetical protein 0.001 0.0042 0.0149
Schistosoma mansoni nuclear hormone receptor 0.001 0.0042 0.0207
Echinococcus multilocularis phosphoserine phosphatase 0.0005 0.0009 0.0033
Leishmania major serine/threonine protein phosphatase, putative 0.004 0.0274 0.0982
Schistosoma mansoni type V p-type atpase isoform 0.0005 0.0009 0.0033
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0018 0.0106 0.0535
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0018 0.0106 0.0535
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0005 0.0009 0.0032
Loa Loa (eye worm) TK/ABL protein kinase 0.0006 0.0012 0.0014
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.004 0.0274 0.1409
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0018 0.0106 0.0359
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0015 0.0082 0.0272
Schistosoma mansoni hypothetical protein 0.026 0.1929 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0115 0.0838 0.4335
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0018 0.0106 0.039
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0242 0.3535
Trypanosoma brucei protein kinase, putative 0.0036 0.0242 0.0892
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0006 0.0012 0.005
Leishmania major proteasome beta 7 subunit, putative 0.0018 0.0106 0.0359
Schistosoma mansoni hypothetical protein 0.0021 0.0129 0.0654
Echinococcus granulosus signal transduction protein lnk realted 0.0006 0.0012 0.005
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0018 0.0106 0.0535
Echinococcus granulosus suppressor of cytokine signaling 7 0.0006 0.0012 0.005
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0126 0.0161
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0126 0.0161
Schistosoma mansoni nuclear hormone receptor 0.001 0.0042 0.0207
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0126 0.0117
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0126 0.0117
Schistosoma mansoni tensin 0.0006 0.0012 0.005
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0143 0.0728
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0045 0.0305 0.1097
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0126 0.0518
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0036 0.0242 0.0863
Schistosoma mansoni tensin-related 0.0006 0.0012 0.005
Giardia lamblia 20S proteasome alpha subunit 2 0.0018 0.0106 0.0359
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0029 0.0188 0.0961
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0126 0.0161
Plasmodium falciparum proteasome subunit beta type-4 0.0018 0.0106 0.0359
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0018 0.0106 0.0359
Echinococcus granulosus NCK adaptor protein 0.0006 0.0012 0.005
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0006 0.0012 0.005
Echinococcus granulosus BC026374 protein S09 family 0.0023 0.0143 0.0728
Echinococcus granulosus tyrosine kinase 0.0006 0.0012 0.005
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0018 0.0106 0.0359
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0126 0.0639
Echinococcus multilocularis N chimaerin 0.0006 0.0012 0.005
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.0042 0.0207
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0018 0.0106 0.0359
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0363 0.2708 1
Schistosoma mansoni cpg binding protein 0.0019 0.0114 0.0578
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0014
Schistosoma mansoni ran 0.0015 0.0082 0.0413
Brugia malayi Telomerase reverse transcriptase 0.0966 0.726 1
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0014
Onchocerca volvulus 0.0021 0.0126 0.0117
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0126 0.0639
Schistosoma mansoni ATPase 0.0005 0.0009 0.0033
Trypanosoma brucei P-type H+-ATPase, putative 0.0005 0.0009 0.0032
Giardia lamblia 20S proteasome alpha subunit 6 0.0018 0.0106 0.0359
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0018 0.0106 0.0535
Trypanosoma brucei P-type H+-ATPase, putative 0.0005 0.0009 0.0032
Loa Loa (eye worm) hypothetical protein 0.0137 0.1001 0.4402
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0242 0.3535
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0015 0.0082 0.0101
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0006 0.0012 0.005
Echinococcus granulosus tyrosine kinase 0.0006 0.0012 0.005
Echinococcus multilocularis phosphoserine phosphatase 0.0005 0.0009 0.0033
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0006 0.0012 0.0003
Onchocerca volvulus 0.0006 0.0012 0.0003
Schistosoma mansoni growth factor receptor-bound protein 0.0006 0.0012 0.005
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0137 0.1001 0.5184
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0042 0.0207
Giardia lamblia Kinase, CMGC MAPK 0.0036 0.0242 0.0863
Onchocerca volvulus 0.0023 0.0143 0.0134
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.004 0.0274 0.4025
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0018 0.0106 0.0359
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0126 0.0639
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0018 0.0106 0.0359
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0126 0.0639
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0015 0.0082 0.0413
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0019 0.0108 0.1508
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0018 0.0106 0.043
Trypanosoma brucei importin beta-1 subunit, putative 0.002 0.0123 0.0454
Loa Loa (eye worm) hypothetical protein 0.004 0.027 0.1157
Brugia malayi Variant SH3 domain containing protein 0.0006 0.0012 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0126 0.0518
Onchocerca volvulus 0.0023 0.0143 0.0134
Brugia malayi Proteasome subunit alpha type 1 0.0018 0.0106 0.0134
Plasmodium vivax importin-beta 2, putative 0.002 0.0123 0.0423
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0042 0.0034
Loa Loa (eye worm) carboxylesterase 0.0137 0.1001 0.4402
Loa Loa (eye worm) carboxylesterase 0.0023 0.0143 0.0594
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0126 0.0161
Brugia malayi nuclear receptor RXR 0.0011 0.0051 0.0059
Brugia malayi SH2 domain containing protein 0.0006 0.0012 0.0005
Schistosoma mansoni hypothetical protein 0.0094 0.0681 0.3519
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0006 0.0012 0.0014
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0018 0.0106 0.039
Echinococcus granulosus copper transporting ATPase 1 0.0005 0.0009 0.0033
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0018 0.0106 0.043
Echinococcus multilocularis GPCR, family 2 0.0021 0.0129 0.0654
Brugia malayi conserved hypotetical protein 0.001 0.0042 0.0046
Brugia malayi Latrophilin receptor protein 2 0.0021 0.0129 0.0165
Toxoplasma gondii HEAT repeat-containing protein 0.002 0.0123 0.0423
Toxoplasma gondii protein phosphatase 2B catalytic subunit, calcineurin family phosphatse superfamily protein 0.004 0.0274 0.0982
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0006 0.0012 0.005
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0018 0.0106 0.0359
Schistosoma mansoni tensin-related 0.0006 0.0012 0.005
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0018 0.0106 0.0359
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0042 0.0149
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0029 0.0188 0.0247
Giardia lamblia 20S proteasome alpha subunit 7 0.0018 0.0106 0.0359
Echinococcus multilocularis proteasome subunit beta type 7 0.0018 0.0106 0.0535
Onchocerca volvulus 0.0006 0.0012 0.0003
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0023 0.0143 0.0728
Toxoplasma gondii RNA-directed DNA polymerase 0.0363 0.2708 1
Leishmania major proteasome alpha 2 subunit, putative 0.0018 0.0106 0.0359
Schistosoma mansoni nuclear receptor 0.001 0.0042 0.0207
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0012 0.0014
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0012 0.0014
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0006 0.0012 0.005
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0014
Brugia malayi Carboxylesterase family protein 0.0023 0.0143 0.0185
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0023 0.0143 0.2035
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0018 0.0106 0.1471
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0143 0.2035
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0126 0.0639
Echinococcus granulosus SH2 domain containing adapter protein F 0.0006 0.0012 0.005
Schistosoma mansoni coup transcription factor 0.0021 0.0126 0.0639
Giardia lamblia 20S proteasome alpha subunit 3 0.0018 0.0106 0.0359
Echinococcus multilocularis signal transduction protein lnk realted 0.0006 0.0012 0.005
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0005 0.0009 0.0033
Schistosoma mansoni suppressor of cytokine signaling 0.0006 0.0012 0.005
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0036 0.0242 0.0863
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0072 0.0511 0.2642
Plasmodium vivax proteasome subunit beta type-7, putative 0.0018 0.0106 0.0359
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0005 0.0009 0.0033
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0018 0.0106 0.043
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.004 0.0274 0.0982
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0018 0.0106 0.0535
Onchocerca volvulus 0.0006 0.0012 0.0003
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0006 0.0012 0.005
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0126 0.0639
Leishmania major telomerase reverse transcriptase, putative 0.0363 0.2708 1
Schistosoma mansoni ATPase 0.0005 0.0009 0.0033
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0036 0.0242 0.0863
Onchocerca volvulus 0.001 0.0042 0.0034
Giardia lamblia 20S proteasome alpha subunit 4 0.0018 0.0106 0.0359
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0018 0.0106 0.0359
Echinococcus multilocularis tyrosine protein kinase Srms 0.0006 0.0012 0.005
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0006 0.0012 0.0014
Leishmania major proteasome alpha 1 subunit, putative 0.0018 0.0106 0.0359
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0042 0.0149
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0029 0.0188 0.0961
Onchocerca volvulus 0.0006 0.0012 0.0003
Echinococcus granulosus acetylcholinesterase 0.0137 0.1001 0.5184
Toxoplasma gondii heat shock protein hslv, putative 0.0018 0.0106 0.0359
Brugia malayi hypothetical protein 0.0056 0.0391 0.0527
Echinococcus multilocularis SHC transforming protein 3 0.0006 0.0012 0.005
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0018 0.0106 0.043
Loa Loa (eye worm) TK/FER protein kinase 0.0006 0.0012 0.0014
Schistosoma mansoni cpg binding protein 0.0019 0.0114 0.0578
Trypanosoma brucei telomerase reverse transcriptase 0.0363 0.2708 1
Echinococcus multilocularis proteasome subunit beta type 6 0.0018 0.0106 0.0535
Loa Loa (eye worm) hypothetical protein 0.0006 0.0012 0.0014
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0006 0.0012 0.005
Echinococcus granulosus phospholipid transporting ATPase VA 0.0005 0.0009 0.0033
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0072 0.0511 0.1862
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0018 0.0106 0.1471
Loa Loa (eye worm) hypothetical protein 0.0021 0.0126 0.0518
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0126 0.0639
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0017 0.0094 0.1289
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0018 0.0106 0.0359
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0018 0.0106 0.0359
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0006 0.0012 0.005
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0093 0.0667 0.2464
Echinococcus granulosus tyrosine protein kinase Fyn 0.0006 0.0012 0.005
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0126 0.0117
Schistosoma mansoni vav2 0.0006 0.0012 0.005
Leishmania major proteasome alpha 1 subunit, putative 0.0018 0.0106 0.0359

Activities

Activity type Activity value Assay description Source Reference
IC50 (ADMET) > 21.35 uM Cytotoxicity against human PBMC cells after 72 hrs by Alamar Blue assay ChEMBL. 21115213
IC50 (functional) > 21.35 uM Cytotoxicity against human HL60 cells after 72 hrs by MTT assay ChEMBL. 21115213
IC50 (functional) > 21.35 uM Cytotoxicity against human MDA-MB-435 cells after 72 hrs by MTT assay ChEMBL. 21115213
IC50 (functional) > 21.35 uM Cytotoxicity against human HCT8 cells after 72 hrs by MTT assay ChEMBL. 21115213
IC50 (functional) = 21.35 uM Cytotoxicity against human SF295 cells after 72 hrs by MTT assay ChEMBL. 21115213
IC50 (ADMET) = 64.2 uM Cytotoxicity against human PBMC after 72 hrs by Alamar blue assay ChEMBL. 21820768
MIC (functional) = 53.35 uM Antitubercular activity against rifampicin-resistant Mycobacterium tuberculosis ATCC 35338 harboring His-526-Tri mutation in rpoB gene after 9 days by resazurin reduction assay ChEMBL. 21820768
MIC (functional) = 106.7 uM Antitubercular activity against isoniazid-resistant Mycobacterium tuberculosis ATCC 35822 harboring Ser-315-Tri mutation in katG gene after 9 days by resazurin reduction assay ChEMBL. 21820768

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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