Detailed information for compound 1509677

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 534.11 | Formula: C27H36ClN3O4S
  • H donors: 2 H acceptors: 3 LogP: 5.13 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1cc(C)c(c(c1C)C)S(=O)(=O)N[C@H](C(=O)N[C@@H]1C[C@@H]2CC[C@H](C1)N2C)Cc1ccc(cc1)Cl
  • InChi: 1S/C27H36ClN3O4S/c1-16-12-25(35-5)17(2)18(3)26(16)36(33,34)30-24(13-19-6-8-20(28)9-7-19)27(32)29-21-14-22-10-11-23(15-21)31(22)4/h6-9,12,21-24,30H,10-11,13-15H2,1-5H3,(H,29,32)/t21-,22+,23-,24-/m0/s1
  • InChiKey: ABECTNWXRXHWDP-KIHHCIJBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens arginine vasopressin receptor 1A Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0031 0.0038 0.0038
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0083 0.0162 0.0161
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0013 0.0374
Schistosoma mansoni hypothetical protein 0.0064 0.0116 0.0115
Giardia lamblia GTOR 0.0062 0.0111 0.1055
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0033 0.0043 0.2661
Brugia malayi MH2 domain containing protein 0.0248 0.0558 0.1387
Loa Loa (eye worm) hypothetical protein 0.0083 0.0162 0.0401
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0244 0.0548 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Toxoplasma gondii FATC domain-containing protein 0.0033 0.0041 0.1292
Schistosoma mansoni hypothetical protein 0.0022 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0152 0.0327 0.0814
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0027 0.0391
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Leishmania major hypothetical protein, conserved 0.0049 0.0082 0.1211
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Onchocerca volvulus 0.003 0.0036 0.0216
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0013 0.0031
Entamoeba histolytica protein kinase, putative 0.0271 0.0612 0.5817
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0019 0.0829
Loa Loa (eye worm) hypothetical protein 0.0043 0.0067 0.0167
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.022 0.049 0.8928
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0089 0.0176 0.0175
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0032 0.0041 0.0041
Echinococcus multilocularis Niemann Pick C1 protein 0.0197 0.0435 0.0435
Echinococcus granulosus survival motor neuron protein 1 0.0474 0.1099 0.1098
Onchocerca volvulus 0.0051 0.0086 0.0524
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0614 0.1433 0.3567
Onchocerca volvulus 0.0051 0.0086 0.0524
Brugia malayi hypothetical protein 0.0043 0.0067 0.0167
Brugia malayi TAR-binding protein 0.0065 0.0118 0.0293
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0018 0.0007 0.0007
Echinococcus multilocularis tumor protein p63 0.0332 0.0759 0.0758
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Brugia malayi Pre-SET motif family protein 0.0089 0.0176 0.0436
Trypanosoma brucei metacaspase 0.0047 0.0075 0.1112
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Schistosoma mansoni wiskott-aldrich syndrome protein 0.0266 0.06 0.0599
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0071 0.0132 0.3933
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0123 0.0259 0.0258
Trichomonas vaginalis STE family protein kinase 0.0271 0.0612 0.3744
Plasmodium vivax vivapain-2 0.0051 0.0086 0.4324
Loa Loa (eye worm) hypothetical protein 0.0201 0.0445 0.1107
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0013 0.0012
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0148 0.0318 0.0317
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0013 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0068 0.0417
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0011 0.0065
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0013 0.0119
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0089 0.0176 0.0175
Loa Loa (eye worm) hypothetical protein 0.0051 0.0086 0.0213
Brugia malayi P21-Rho-binding domain containing protein 0.0266 0.06 0.1493
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.0336 0.6123
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0047 0.0075 0.0075
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.0013 0.0374
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0455 0.1052 0.1052
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0013 0.0187
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0118 0.0118
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative 0.0015 0.0001 0.0003
Echinococcus multilocularis muscleblind protein 0.0152 0.0327 0.0327
Trypanosoma cruzi cysteine peptidase, putative 0.0195 0.0431 0.6427
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0062 0.0111 0.1055
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0064 0.0943
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.016 0.0159
Echinococcus multilocularis survival motor neuron protein 1 0.0474 0.1099 0.1098
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0064 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0075 0.0459
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Schistosoma mansoni hypothetical protein 0.0266 0.06 0.0599
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0059 0.0555
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Brugia malayi Protein kinase domain 0.0455 0.1052 0.2619
Echinococcus multilocularis apoptotic protease activating factor 1 0.0043 0.0067 0.0067
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0033 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0082 0.0159 0.0158
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.0022 0.0315
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.0162 1
Schistosoma mansoni ferritin 0.0018 0.0006 0.0005
Toxoplasma gondii NADPH-glutathione reductase 0.0033 0.0043 0.1354
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0068 0.0067
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0027 0.0026
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0033 0.0043 0.1278
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0068 0.2117
Schistosoma mansoni caspase-3 (C14 family) 0.0123 0.0259 0.0258
Loa Loa (eye worm) acetyltransferase 0.0148 0.0318 0.0789
Schistosoma mansoni protein kinase 0.0266 0.06 0.0599
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0025
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0013 0.0374
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0018 0.0007 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0053 0.009 0.1334
Entamoeba histolytica hypothetical protein 0.0039 0.0057 0.0533
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0057 0.0056
Onchocerca volvulus 0.0089 0.0176 0.107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0041 0.0252
Loa Loa (eye worm) Smad1 0.0017 0.0004 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0084 0.0516
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0083 0.1502
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0011 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0065
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0079 0.0078
Brugia malayi MH2 domain containing protein 0.0017 0.0004 0.0009
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0107 0.0106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0051 0.0309
Schistosoma mansoni hypothetical protein 0.0266 0.06 0.0599
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0083 0.0162 0.8291
Plasmodium falciparum thioredoxin reductase 0.0096 0.0194 1
Onchocerca volvulus 0.0051 0.0086 0.0524
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.0013 0.0374
Echinococcus multilocularis replication factor c subunit 1 0.002 0.0011 0.001
Brugia malayi hypothetical protein 0.002 0.0011 0.0025
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0455 0.1052 0.1052
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0089 0.0176 0.5529
Loa Loa (eye worm) hypothetical protein 0.0064 0.0116 0.0287
Echinococcus multilocularis cpg binding protein 0.0032 0.004 0.004
Loa Loa (eye worm) inositol-1 0.0148 0.0317 0.0789
Plasmodium vivax unspecified product 0.0026 0.0027 0.1192
Brugia malayi latrophilin 2 splice variant baaae 0.0137 0.0293 0.0728
Echinococcus multilocularis Smad4 0.0017 0.0004 0.0003
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0063 0.0931
Schistosoma mansoni cpg binding protein 0.0032 0.004 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0063 0.0384
Plasmodium vivax vivapain-1 0.0026 0.0027 0.1192
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0013 0.0031
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0244 0.0548 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.022 0.049 0.8928
Echinococcus granulosus ferritin 0.0018 0.0006 0.0005
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0027 0.0391
Brugia malayi MH1 domain containing protein 0.0017 0.0004 0.0009
Echinococcus granulosus cathepsin L cysteine protease 0.0026 0.0027 0.0026
Mycobacterium tuberculosis Probable oxidoreductase 0.0244 0.0548 1
Brugia malayi Cathepsin L-like precursor 0.0017 0.0004 0.0009
Toxoplasma gondii ATPase, AAA family protein 0.002 0.0011 0.032
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0029 0.0032 0.057
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0089 0.0176 0.0175
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0071 0.0132 0.3933
Echinococcus granulosus caspase 2 0.009 0.0179 0.0179
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0017
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0019 0.027
Echinococcus granulosus Niemann Pick C1 protein 0.0197 0.0435 0.0435
Plasmodium falciparum thioredoxin reductase 0.0033 0.0043 0.1784
Echinococcus granulosus neural Wiskott Aldrich syndrome protein 0.0266 0.06 0.0599
Echinococcus granulosus smad 0.0017 0.0004 0.0003
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0063 0.0931
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0295 0.0671 1
Onchocerca volvulus 0.0082 0.016 0.0972
Chlamydia trachomatis DNA ligase 0.002 0.0011 0.0629
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0042 0.0064 0.0601
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0004 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0041 0.0252
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0013 0.0031
Schistosoma mansoni hypothetical protein 0.0097 0.0195 0.0194
Mycobacterium ulcerans bacterioferritin BfrA 0.0018 0.0006 0.0153
Loa Loa (eye worm) hypothetical protein 0.0449 0.104 0.2588
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0064 0.0116 0.0115
Trypanosoma brucei PAB1-binding protein , putative 0.0049 0.0082 0.1211
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0004 0.0003
Echinococcus multilocularis expressed protein 0.0018 0.0006 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0166 0.1015
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0086 0.0527
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0013 0.0374
Brugia malayi Cathepsin L-like precursor 0.0051 0.0086 0.0213
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0013 0.008
Brugia malayi RNA binding protein 0.0065 0.0118 0.0293
Entamoeba histolytica hypothetical protein 0.0039 0.0057 0.0533
Echinococcus granulosus expressed conserved protein 0.0185 0.0407 0.0406
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.022 0.049 0.8928
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0083 0.0162 0.2941
Schistosoma mansoni hypothetical protein 0.0082 0.0159 0.0158
Trypanosoma cruzi cruzipain precursor, putative 0.0195 0.0431 0.6427
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.009 0.2659
Onchocerca volvulus 0.002 0.0011 0.0062
Echinococcus multilocularis PAK box P21 Rho binding 0.0266 0.06 0.0599
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0079 0.0078
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0013 0.0187
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0013 0.0031
Schistosoma mansoni ferritin light chain 0.0018 0.0006 0.0005
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0075 0.2354
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0029 0.0034 0.0498
Brugia malayi cathepsin L-like precursor 0.0034 0.0046 0.0112
Brugia malayi P21-Rho-binding domain containing protein 0.0266 0.06 0.1493
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0068 0.2117
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0118 0.0293
Plasmodium falciparum metacaspase-like protein 0.0047 0.0075 0.3511
Brugia malayi Thioredoxin reductase 0.0096 0.0194 0.0482
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0013 0.0229
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.0671 1
Trypanosoma cruzi p21-activated kinase 3, putative 0.0189 0.0416 0.6199
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Schistosoma mansoni caspase-7 (C14 family) 0.009 0.0179 0.0179
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0033 0.0043 0.064
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0079 0.0078
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0132 0.028 0.5103
Schistosoma mansoni ferritin 0.0018 0.0006 0.0005
Echinococcus granulosus expressed protein 0.0018 0.0006 0.0005
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Echinococcus multilocularis smad 0.0017 0.0004 0.0003
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0054 0.0093 0.1695
Trypanosoma cruzi metacaspase, putative 0.0047 0.0075 0.1112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0013 0.0031
Plasmodium vivax metacaspase 1, putative 0.0047 0.0075 0.3736
Trypanosoma cruzi FHA domain containing protein, putative 0.002 0.0011 0.0151
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0013 0.0475
Onchocerca volvulus 0.0049 0.008 0.0485
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0013 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Brugia malayi nuclear hormone receptor 0.0021 0.0013 0.0031
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Schistosoma mansoni hypothetical protein 0.0137 0.0293 0.0292
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0125 0.0124
Loa Loa (eye worm) RNA binding protein 0.0065 0.0118 0.0293
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0057 0.0056
Onchocerca volvulus 0.0051 0.0086 0.0524
Brugia malayi Muscleblind-like protein 0.0152 0.0327 0.0814
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0019 0.027
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0148 0.0317 0.9439
Echinococcus granulosus Ankyrin 0.0031 0.0038 0.0038
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.0195 0.0484
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0013 0.0396
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0013 0.0031
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0079 0.0078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0013 0.0031
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0013 0.0187
Echinococcus granulosus cathepsin L cysteine proteinase 0.0051 0.0086 0.0086
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0043 0.1212
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0033 0.0043 0.064
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0013 0.0187
Brugia malayi Calcitonin receptor-like protein seb-1 0.0201 0.0445 0.1107
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0033 0.0043 0.1784
Brugia malayi Cathepsin L-like precursor 0.0034 0.0046 0.0112
Mycobacterium tuberculosis Probable reductase 0.022 0.049 0.8928
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0013 0.0031
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0031
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0013 0.0229
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0086 0.0213
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0086 0.0086
Schistosoma mansoni tyrosine kinase 0.0266 0.06 0.0599
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0064 0.039
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0064 0.0943
Mycobacterium tuberculosis Probable dehydrogenase 0.022 0.049 0.8928
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0176 0.0175
Echinococcus granulosus replication factor c subunit 1 0.002 0.0011 0.001
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0062 0.0111 0.1655
Brugia malayi Cathepsin L-like precursor 0.0051 0.0086 0.0213
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0079 0.0195
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0013 0.0012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.064
Echinococcus granulosus thioredoxin glutathione reductase 0.0096 0.0194 0.0194
Schistosoma mansoni topbp1 0.002 0.0011 0.001
Schistosoma mansoni inositol monophosphatase 0.0148 0.0317 0.0317
Echinococcus multilocularis protein dispatched 1 0.0097 0.0195 0.0194
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0019 0.057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0063 0.0384
Onchocerca volvulus 0.0051 0.0086 0.0524
Schistosoma mansoni apoferritin-2 0.0018 0.0006 0.0005
Brugia malayi Cathepsin L-like precursor 0.0051 0.0086 0.0213
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Toxoplasma gondii cathepsin CPL 0.0051 0.0086 0.2707
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0045
Plasmodium vivax replication factor C subunit 1, putative 0.002 0.0011 0.0348
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.0013 0.0374
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0017 0.0016
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.022 0.049 0.8928
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0019 0.0415
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0189 0.0416 0.1035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.009 0.0549
Loa Loa (eye worm) hypothetical protein 0.0474 0.1099 0.2734
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0013 0.0374
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0189 0.0416 0.1035
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0019 0.057
Echinococcus granulosus Smad4 0.0017 0.0004 0.0003
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0118 0.0118
Echinococcus multilocularis thioredoxin glutathione reductase 0.0096 0.0194 0.0194
Echinococcus multilocularis caspase 8 0.0047 0.0075 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0045
Schistosoma mansoni ferritin 0.0018 0.0006 0.0005
Brugia malayi hypothetical protein 0.0032 0.004 0.0098
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0019 0.1121
Schistosoma mansoni inositol monophosphatase 0.0148 0.0317 0.0317
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0086 0.0086
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0033 0.0043 0.064
Schistosoma mansoni ankyrin 23/unc44 0.0031 0.0038 0.0038
Echinococcus granulosus cysteine protease 0.0026 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0025
Entamoeba histolytica hypothetical protein 0.002 0.0011 0.0096
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0013 0.0374
Leishmania major cathepsin L-like protease 0.0051 0.0086 0.1279
Echinococcus granulosus histone lysine methyltransferase setb 0.0089 0.0176 0.0175
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.002 0.0011 0.0302
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0027 0.0249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0061 0.0373
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0201 0.0445 0.1107
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0013 0.0012
Echinococcus granulosus PAK box P21 Rho binding 0.0266 0.06 0.0599
Schistosoma mansoni smad 0.0017 0.0004 0.0003
Onchocerca volvulus 0.0034 0.0046 0.0276
Trichomonas vaginalis STE family protein kinase 0.0455 0.1052 0.6434
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Schistosoma mansoni cathepsin s 0.0017 0.0004 0.0004
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0051 0.0086 0.4119
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0086 0.0086
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0013 0.0031
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0083 0.1502
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0148 0.0317 0.4725
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.009 0.0549
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0132 0.0329
Brugia malayi Cathepsin L-like precursor 0.0051 0.0086 0.0213
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0086 0.0815
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0064 0.0116 0.0115
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0018 0.0007 0.0101
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0107 0.3162
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.064
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0013 0.0075
Onchocerca volvulus 0.0043 0.0067 0.0409
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0019 0.0765
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Loa Loa (eye worm) phosphatidylinositol 3 0.0032 0.0041 0.0101
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.1427 0.338 0.3379
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0085 0.1255
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0068 0.3341
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0019 0.0538
Echinococcus granulosus caspase 3 0.0077 0.0147 0.0146
Echinococcus granulosus apoptotic protease activating factor 1 0.0043 0.0067 0.0067
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0062 0.0111 0.1055
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0018 0.0006 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0013 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0013 0.0012
Giardia lamblia NADH oxidase lateral transfer candidate 0.0033 0.0043 0.0408
Trichomonas vaginalis replication factor C large subunit, putative 0.002 0.0011 0.0065
Brugia malayi glutathione reductase 0.0096 0.0194 0.0482
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0068 0.0413
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0013 0.0031
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0004 0.0053
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0047 0.0075 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0013 0.0031
Echinococcus granulosus Niemann Pick C1 protein 0.0282 0.0638 0.0637
Brugia malayi hypothetical protein 0.0149 0.0319 0.0794
Echinococcus granulosus cpg binding protein 0.0032 0.004 0.004
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0062 0.0111 0.1655
Schistosoma mansoni hypothetical protein 0.0064 0.0116 0.0115
Entamoeba histolytica cysteine protease, putative 0.0051 0.0086 0.0815
Leishmania major cathepsin L-like protease 0.0195 0.0431 0.6427
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0013 0.0374
Loa Loa (eye worm) transcription factor SMAD2 0.0248 0.0558 0.1387
Onchocerca volvulus 0.0051 0.0086 0.0524
Trypanosoma cruzi cysteine peptidase, putative 0.0051 0.0086 0.1279
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0031 0.0038 0.0038
Brugia malayi Cell death protein 3 precursor 0.009 0.0179 0.0445
Loa Loa (eye worm) hypothetical protein 0.009 0.0179 0.0445
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0071 0.0132 0.2408
Toxoplasma gondii hypothetical protein 0.0048 0.0078 0.2432
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0013 0.0187
Schistosoma mansoni hypothetical protein 0.0064 0.0116 0.0115
Loa Loa (eye worm) hypothetical protein 0.0042 0.0064 0.0157
Schistosoma mansoni ferritin 0.0018 0.0006 0.0005
Schistosoma mansoni smad1 5 8 and 0.0017 0.0004 0.0003
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0013 0.0396
Brugia malayi acetyltransferase, GNAT family protein 0.0148 0.0318 0.0789
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0013 0.0132
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0025
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0013 0.0187
Trypanosoma cruzi major cysteine proteinase, putative 0.0154 0.0331 0.4933
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0013 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0176 0.0175
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0013 0.0187
Trypanosoma cruzi cysteine protease, putative 0.0026 0.0027 0.0391
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0013 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Schistosoma mansoni protein kinase 0.0455 0.1052 0.1052
Echinococcus multilocularis geminin 0.0165 0.0359 0.0358
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.002 0.0011 0.0161
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0027 0.0249
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0079 0.0078
Loa Loa (eye worm) hypothetical protein 0.0089 0.0176 0.0436
Schistosoma mansoni smad1 5 8 and 0.0017 0.0004 0.0003
Brugia malayi ecdysteroid receptor 0.0021 0.0013 0.0031
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0013 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0041 0.0252
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0083 0.0162 0.0161
Treponema pallidum DNA ligase (lig) 0.002 0.0011 0.0321
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0009
Plasmodium falciparum cysteine proteinase falcipain 3 0.0051 0.0086 0.4119
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Brugia malayi topoisomerase 0.002 0.0011 0.0025
Schistosoma mansoni hypothetical protein 0.0431 0.0996 0.0995
Leishmania major phosphatidylinositol kinase related protein, putative 0.0021 0.0013 0.018
Plasmodium falciparum cysteine proteinase falcipain 1 0.0026 0.0027 0.0875
Loa Loa (eye worm) MH2 domain-containing protein 0.0248 0.0558 0.1387
Loa Loa (eye worm) hypothetical protein 0.0026 0.0027 0.0065
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0013 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0449 0.104 0.6357
Brugia malayi Cathepsin L-like precursor 0.0051 0.0086 0.0213
Brugia malayi Niemann-Pick C1 protein precursor 0.0197 0.0435 0.1083
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0017 0.0004 0.0009
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.008 0.0079
Plasmodium vivax vivapain-2 0.0051 0.0086 0.4324
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.064
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0013 0.0012
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0013 0.0187
Schistosoma mansoni hypothetical protein 0.0266 0.06 0.0599
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0013 0.0374
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0064 0.0116 0.0115
Brugia malayi DKFZp564C0469 protein 0.002 0.0011 0.0025
Toxoplasma gondii thioredoxin reductase 0.0096 0.0194 0.6115
Schistosoma mansoni serine/threonine protein kinase 0.0266 0.06 0.0599
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0013 0.0012
Echinococcus multilocularis protein patched 0.0085 0.0166 0.0165
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0033 0.0043 0.207
Echinococcus multilocularis expressed conserved protein 0.0185 0.0407 0.0406
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0004 0.0003
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0033 0.0043 0.1354
Echinococcus multilocularis cathepsin L 0.0026 0.0027 0.0026
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0022 0.0054
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.064
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.002 0.0011 0.0025
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0079 0.0078
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0075 0.2354
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.016 0.0396
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0053 0.009 0.1334
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0086 0.0815
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.1427 0.338 0.3379
Echinococcus granulosus ubiquitin specific protease 41 0.0042 0.0064 0.0063
Entamoeba histolytica hypothetical protein 0.0039 0.0057 0.0533
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0027 0.0249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0111 0.0682
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0032 0.1149
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0013 0.0229
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0149 0.0319 0.0794
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0132 0.1254
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0004 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0111 0.0682
Loa Loa (eye worm) hypothetical protein 0.0049 0.008 0.0198
Giardia lamblia Kinase, STE STE20 0.0455 0.1052 1
Plasmodium vivax thioredoxin reductase, putative 0.0096 0.0194 1
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0189 0.0416 0.1035
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0041 0.0606
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0304 0.0693 0.0692
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0132 0.3933
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0178 0.0391 0.5821
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0085 0.0166 0.0166
Trichomonas vaginalis STE family protein kinase 0.0455 0.1052 0.6434
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0013 0.0012
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0013 0.0012
Plasmodium vivax SET domain protein, putative 0.0089 0.0176 0.9024
Toxoplasma gondii target of rapamycin (TOR), putative 0.005 0.0084 0.2647
Onchocerca volvulus Netrin receptor homolog 0.0031 0.0038 0.0229
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0455 0.1052 0.1052
Trichomonas vaginalis ferritin, putative 0.0018 0.0006 0.0035
Brugia malayi hypothetical protein 0.002 0.0011 0.0025
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0201 0.0445 0.1107
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0013 0.0012
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0132 0.3933
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0013 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0084 0.0516
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0075
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0033 0.0043 0.1278
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0111 0.0682
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0013 0.0229
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0079 0.0078
Onchocerca volvulus 0.0071 0.0132 0.0807
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0059 0.2629
Echinococcus granulosus nuclear factor of activated T cells 5 0.0304 0.0693 0.0692
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0063 0.0931
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0132 0.028 0.5103
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Brugia malayi Inositol-1 0.0148 0.0317 0.0789
Loa Loa (eye worm) fibroinase 0.0051 0.0086 0.0213
Leishmania major trypanothione reductase 0.0096 0.0194 0.2889
Entamoeba histolytica hypothetical protein 0.0266 0.06 0.5698
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0082 0.1211
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0062 0.0111 0.0111
Schistosoma mansoni cpg binding protein 0.0032 0.004 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0075 0.0459
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0062 0.0111 0.0111
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0013 0.0012
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0031 0.0038 0.0038
Schistosoma mansoni niemann-pick C1 (NPC1) 0.02 0.0443 0.0442
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0104 0.0212 0.0526
Loa Loa (eye worm) cysteine protease 0.0051 0.0086 0.0213
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0013 0.0031
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0004 0.0009
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.0162 0.5089
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0065
Leishmania major cysteine peptidase A (CPA) 0.0051 0.0086 0.1279
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0176 0.0175
Echinococcus multilocularis GPCR, family 2 0.0064 0.0116 0.0115
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0068 0.0413
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0118 0.0118
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0013 0.0012
Schistosoma mansoni ferritin light chain 0.0018 0.0006 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0013 0.0012
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0132 0.2408
Onchocerca volvulus 0.0097 0.0195 0.1189
Loa Loa (eye worm) hypothetical protein 0.0049 0.0082 0.0202
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0011 0.0065
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0118 0.0118
Entamoeba histolytica p21-activated kinase 0.0455 0.1052 1
Echinococcus multilocularis ubiquitin specific protease 41 0.0042 0.0064 0.0063
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0029
Schistosoma mansoni chromosome transmission fidelity factor 0.002 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0137 0.0293 0.0728
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0013 0.0187
Mycobacterium ulcerans hypothetical protein 0.0071 0.0132 0.3933
Schistosoma mansoni hypothetical protein 0.0043 0.0067 0.0067
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0019 0.0432
Echinococcus granulosus tumor protein p63 0.0332 0.0759 0.0758
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0013 0.0374
Onchocerca volvulus 0.0021 0.0013 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0075 0.0459
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0013 0.0374
Echinococcus granulosus nibrin 0.002 0.0011 0.001
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0083 0.0162 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0053 0.009 0.1628
Schistosoma mansoni hypothetical protein 0.0039 0.0057 0.0056
Echinococcus multilocularis caspase 3 0.0077 0.0147 0.0146
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0118 0.0293
Schistosoma mansoni serine/threonine protein kinase 0.0189 0.0416 0.0416
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Leishmania major metacaspase, putative 0.0047 0.0075 0.1112
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.002 0.0011 0.032
Schistosoma mansoni cpg binding protein 0.003 0.0036 0.0035
Trypanosoma brucei metacaspase MCA3 0.0047 0.0075 0.1112
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0064 0.0063
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0148 0.0317 0.1939
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0107 0.3162
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0064 0.0116 0.0287
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0007 0.0017
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0043 0.064
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0025
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0148 0.0317 0.4725
Brugia malayi Pre-SET motif family protein 0.0614 0.1433 0.3567
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0051 0.0086 0.4119
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0013 0.0031
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0042 0.0064 0.0943
Giardia lamblia Replication factor C, subunit 1 0.002 0.0011 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0041 0.0252
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0046 0.0112
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0123 0.0259 0.0258
Plasmodium vivax glutathione reductase, putative 0.0096 0.0194 1
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0107 0.0106
Schistosoma mansoni survival motor neuron protein 0.0097 0.0195 0.0194
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.0162 0.5089
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.0162 1
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0033 0.0041 0.0611
Loa Loa (eye worm) hypothetical protein 0.0053 0.009 0.0222
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0032 0.0041 0.0606
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0013 0.0013
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0148 0.0317 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0051 0.0086 0.0213
Entamoeba histolytica hypothetical protein 0.0266 0.06 0.5698
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0013 0.0374
Schistosoma mansoni serine/threonine protein kinase 0.0189 0.0416 0.0416
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0064 0.0116 0.0115
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0043 0.064
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0107 0.0106
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0043 0.1212
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0083 0.0162 0.8229
Onchocerca volvulus 0.0698 0.1636 1
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0021 0.0013 0.0229
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0327 0.0327
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0056 0.0342
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0107 0.335
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0084 0.0516
Treponema pallidum NADH oxidase 0.0033 0.0043 0.242
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0019 0.033
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0086 0.0524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0063 0.0384
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.064
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0148 0.0317 0.4725
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0455 0.1052 0.1052
Echinococcus granulosus cathepsin l cysteine peptidase 0.0051 0.0086 0.0086
Mycobacterium tuberculosis Putative ferredoxin reductase 0.022 0.049 0.8928
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0032 0.0041 0.0606
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0033 0.0043 0.0043
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0062 0.0111 0.1655
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.009 0.0549
Trichomonas vaginalis set domain proteins, putative 0.0698 0.1636 1
Echinococcus granulosus tar DNA binding protein 0.0065 0.0118 0.0118
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0033 0.0041 0.0611
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0004 0.0003
Echinococcus multilocularis serine protein kinase ATM 0.0033 0.0041 0.0041
Trichomonas vaginalis inositol monophosphatase, putative 0.0015 0.0001 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0013 0.0031
Echinococcus granulosus 3'partial|serine:threonine protein kinase PAK 2 0.0266 0.06 0.0599
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Brugia malayi Probable ClpP-like protease 0.0083 0.0162 0.0401
Loa Loa (eye worm) hypothetical protein 0.0071 0.0132 0.0329
Trypanosoma brucei metacaspase 5, putative 0.0047 0.0075 0.1112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Plasmodium vivax ataxin-2 like protein, putative 0.0049 0.0082 0.4084
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0026 0.0027 0.0391
Schistosoma mansoni protein kinase 0.0271 0.0612 0.0612
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0013 0.0031
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.002 0.0011 0.0096
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0029 0.0032 0.1457
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.016 0.0159
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0086 0.0086
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0244 0.0548 1
Echinococcus granulosus death domain containing protein 0.0031 0.0038 0.0038
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0033 0.0043 0.0783
Trypanosoma cruzi cysteine peptidase, putative 0.0195 0.0431 0.6427
Echinococcus multilocularis Niemann Pick C1 protein 0.0282 0.0638 0.0637
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0027 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Loa Loa (eye worm) P21-Rho-binding domain-containing protein 0.0266 0.06 0.1493
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0013 0.0012
Trypanosoma cruzi trypanothione reductase, putative 0.0096 0.0194 0.2889
Entamoeba histolytica acyl-coA synthetase, putative 0.0071 0.0132 0.1254
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.0671 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Schistosoma mansoni hypothetical protein 0.0064 0.0116 0.0115
Echinococcus multilocularis neural Wiskott Aldrich syndrome protein 0.0266 0.06 0.0599
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Loa Loa (eye worm) hypothetical protein 0.0053 0.009 0.0222
Schistosoma mansoni fkbp-rapamycin associated protein 0.0018 0.0007 0.0007
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0018 0.0006 0.0094
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0071 0.0132 0.2408
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0063 0.0384
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0013 0.0374
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0132 0.1254
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.009 0.0549
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0042 0.0064 0.0157
Echinococcus granulosus Protein patched homolog 1 0.0085 0.0166 0.0165
Entamoeba histolytica hypothetical protein 0.0039 0.0057 0.0533
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0013 0.0374
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Echinococcus granulosus geminin 0.0165 0.0359 0.0358
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0013 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0078 0.0474
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0011 0.0151
Onchocerca volvulus 0.0021 0.0013 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0065
Schistosoma mansoni smad1 5 8 and 0.0017 0.0004 0.0003
Trichomonas vaginalis glutathione reductase, putative 0.0033 0.0043 0.0266
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0084 0.0516
Plasmodium vivax hypothetical protein, conserved 0.0047 0.0075 0.3736
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0455 0.1052 0.1052
Echinococcus granulosus dnaJ subfamily B 0.0431 0.0996 0.0995
Trypanosoma brucei Metacaspase-4 0.0047 0.0075 0.1112
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0027 0.0391
Schistosoma mansoni hypothetical protein 0.0165 0.0359 0.0358
Schistosoma mansoni Smad4 0.0017 0.0004 0.0003
Trypanosoma cruzi cruzipain precursor, putative 0.0017 0.0004 0.0053
Loa Loa (eye worm) hypothetical protein 0.0152 0.0327 0.0814
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.0038 0.0093
Onchocerca volvulus 0.0051 0.0086 0.0524
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0085 0.0166 0.0412
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0027 0.0163
Loa Loa (eye worm) hypothetical protein 0.0071 0.0132 0.0329
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0006 0.0103
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0071 0.0132 0.3933
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0051 0.0309
Brugia malayi CHE-14 protein 0.0085 0.0166 0.0412
Loa Loa (eye worm) hypothetical protein 0.0085 0.0166 0.0412
Schistosoma mansoni hypothetical protein 0.0031 0.0038 0.0038
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0018 0.0006 0.0094
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0298 0.4441
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0011 0.0151
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0132 0.0329
Plasmodium vivax vivapain-3 0.0026 0.0027 0.1192
Echinococcus granulosus inositol monophosphatase 1 0.0148 0.0317 0.0317
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0013 0.0012
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0054 0.0093 0.1695
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0148 0.0317 0.4725
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.016 0.0159
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0013 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0075 0.0459
Onchocerca volvulus Cathepsin F homolog 0.0051 0.0086 0.0524
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0041 0.0606
Toxoplasma gondii hypothetical protein 0.0029 0.0032 0.0986
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0013 0.0031
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0013 0.0031
Schistosoma mansoni caspase-7 (C14 family) 0.0123 0.0259 0.0258
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0093
Brugia malayi Cathepsin L-like precursor 0.0051 0.0086 0.0213
Schistosoma mansoni peptidase Clp (S14 family) 0.0083 0.0162 0.0161
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0032 0.0041 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0063 0.0384
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.1692 0.4016 1
Echinococcus granulosus peptidase Clp S14 family 0.0054 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0041 0.0254
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0118 0.0293
Echinococcus granulosus caspase 8 0.0047 0.0075 0.0075
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2478 0.5897 0.5897
Schistosoma mansoni DNA ligase IV 0.002 0.0011 0.001
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0033 0.0043 0.0107
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0011 0.0151
Echinococcus granulosus sterol regulatory element binding protein 0.0085 0.0166 0.0165
Schistosoma mansoni patched 1 0.0085 0.0166 0.0165
Echinococcus multilocularis nibrin 0.002 0.0011 0.001
Brugia malayi steroid hormone receptor 0.0021 0.0013 0.0031
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0011 0.0065
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0013 0.0396
Echinococcus multilocularis peptidase Clp (S14 family) 0.0054 0.0093 0.0093
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0011 0.0065
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0013 0.0013
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0455 0.1052 0.1052
Mycobacterium ulcerans hypothetical protein 0.0156 0.0336 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0075 0.2354
Echinococcus granulosus netrin receptor unc 5 0.0031 0.0038 0.0038
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0032 0.1672
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0013 0.0075
Brugia malayi Smad1 0.0017 0.0004 0.0009
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0043 0.064
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0032 0.0041 0.0041
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0038 0.0093
Entamoeba histolytica protein kinase, putative 0.0455 0.1052 1
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0046 0.0045
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0148 0.0317 0.301
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0013 0.0012
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0062 0.0111 0.0276
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0079 0.0195
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0082 0.1211
Entamoeba histolytica cysteine proteinase 2 0.0026 0.0027 0.0249
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.0162 0.4803
Echinococcus granulosus muscleblind protein 0.0152 0.0327 0.0327
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0082 0.3871
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0022 0.0054
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0027 0.0388
Onchocerca volvulus 0.0149 0.0319 0.195
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0013 0.0031
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0064 0.039
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0004 0.0009
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.0298 0.4441
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0062 0.0111 0.1655
Echinococcus multilocularis caspase 0.0123 0.0259 0.0258
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0148 0.0318 0.0317
Echinococcus multilocularis caspase 2 0.009 0.0179 0.0179
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0132 0.1968
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0018 0.0007 0.0064
Loa Loa (eye worm) ctsf protein 0.0051 0.0086 0.0213
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0013 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0064 0.039
Loa Loa (eye worm) glutathione reductase 0.0096 0.0194 0.0482
Trypanosoma cruzi metacaspase, putative 0.0047 0.0075 0.1112
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0019 0.033
Leishmania major cathepsin L-like protease 0.0051 0.0086 0.1279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0042 0.0064 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Echinococcus multilocularis inositol monophosphatase 1 0.0148 0.0317 0.0317
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0086 0.0527
Trypanosoma cruzi cysteine peptidase, putative 0.0026 0.0027 0.0391
Brugia malayi WH1 domain containing protein 0.0266 0.06 0.1493
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0013 0.0031
Brugia malayi CXXC zinc finger family protein 0.003 0.0036 0.0088
Brugia malayi Protein kinase domain containing protein 0.0036 0.0051 0.0125
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0054 0.0093 0.1695
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0013 0.0229
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.002 0.0011 0.0185
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0086 0.0213
Loa Loa (eye worm) hypothetical protein 0.0034 0.0046 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0064 0.0063
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0189 0.0416 0.6199
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0027 0.0065
Loa Loa (eye worm) hypothetical protein 0.0034 0.0046 0.0112
Leishmania major mitochondrial DNA polymerase beta 0.0295 0.0671 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0013 0.0012
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0033 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0082 0.016 0.0396
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0132 0.3933
Schistosoma mansoni hypothetical protein 0.0165 0.0359 0.0358
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0084 0.0516
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0197 0.0435 0.4134
Brugia malayi hypothetical protein 0.0474 0.1099 0.2734
Echinococcus multilocularis sterol regulatory element binding protein 0.0085 0.0166 0.0165
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0013 0.0031
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0013 0.0075
Toxoplasma gondii non-specific serine/threonine protein kinase 0.002 0.0012 0.0371
Loa Loa (eye worm) hypothetical protein 0.0053 0.009 0.0222
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0062 0.0111 0.1655
Trichomonas vaginalis STE family protein kinase 0.0455 0.1052 0.6434
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0043 0.064
Echinococcus multilocularis cysteine protease 0.0051 0.0086 0.0086
Trypanosoma cruzi target of rapamycin kinase 3 0.0053 0.009 0.1334
Brugia malayi Pax transcription activation domain interacting protein 0.002 0.0011 0.0025
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0063 0.0931
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0057 0.0056
Plasmodium falciparum acyl-CoA synthetase 0.0053 0.009 0.431
Onchocerca volvulus 0.0021 0.0013 0.0077
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0107 0.1583
Leishmania major cathepsin L-like protease 0.0051 0.0086 0.1279
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0013 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0013 0.0031
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0033 0.0041 0.0041
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0148 0.0317 1
Echinococcus multilocularis dnaJ subfamily B 0.0431 0.0996 0.0995
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0084 0.0516
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0013 0.0031
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.064
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0075 0.0459
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0068 0.0417
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0033 0.0043 0.1784
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0027 0.0065
Schistosoma mansoni topbp1 0.002 0.0011 0.001
Echinococcus granulosus cathepsin L 0.0026 0.0027 0.0026
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0062 0.0111 0.0111
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0071 0.0132 0.3933
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0132 0.2408
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0019 0.0538
Brugia malayi Uncoordinated protein 44 0.0031 0.0038 0.0093
Mycobacterium ulcerans bacterioferritin BfrB 0.0018 0.0006 0.0153
Schistosoma mansoni hypothetical protein 0.0082 0.0159 0.0158
Toxoplasma gondii LsmAD domain-containing protein 0.0049 0.0082 0.2563
Echinococcus granulosus cathepsin l1 0.0051 0.0086 0.0086
Onchocerca volvulus 0.0021 0.0013 0.0077
Onchocerca volvulus Cell death protein 3 homolog 0.009 0.0179 0.1091
Schistosoma mansoni netrin receptor unc5 0.0031 0.0038 0.0038
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Echinococcus multilocularis cysteine protease 0.0051 0.0086 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0013 0.0031
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0059 0.0555
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.0013 0.0374
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0027 0.0249
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0013 0.0031
Echinococcus granulosus serine protein kinase ATM 0.0033 0.0041 0.0041
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0013 0.0012
Echinococcus multilocularis ferritin 0.0018 0.0006 0.0005
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0189 0.0416 0.2543
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0031
Schistosoma mansoni apoferritin-2 0.0018 0.0006 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0075 0.0459
Trichomonas vaginalis inositol monophosphatase, putative 0.0015 0.0001 0.0003
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0013 0.0229
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0132 0.0329
Echinococcus multilocularis PAK box P21 Rho binding 0.0271 0.0612 0.0612
Leishmania major phosphatidylinositol 3-kinase, putative 0.0032 0.0041 0.0606
Brugia malayi cathepsin F-like cysteine proteinase 0.0017 0.0004 0.0009
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0086 0.0086
Brugia malayi Latrophilin receptor protein 2 0.0064 0.0116 0.0287
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0065
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0132 0.1968
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Trypanosoma cruzi cysteine peptidase, putative 0.0195 0.0431 0.6427
Brugia malayi MH1 domain containing protein 0.0017 0.0004 0.0009
Brugia malayi hypothetical protein 0.0039 0.0057 0.014
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0082 0.3871
Entamoeba histolytica hypothetical protein 0.0033 0.0041 0.0389
Brugia malayi nuclear receptor NHR-88 0.0021 0.0013 0.0031
Plasmodium vivax acyl-CoA synthetase, putative 0.0053 0.009 0.4507
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0083 0.1502
Loa Loa (eye worm) latrophilin receptor protein 2 0.0064 0.0116 0.0287
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0013 0.0229
Trypanosoma cruzi metacaspase 5, putative 0.0047 0.0075 0.1112
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Leishmania major cathepsin L-like protease 0.0051 0.0086 0.1279
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0013 0.0229
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0013 0.0012
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0036 0.0088
Loa Loa (eye worm) hypothetical protein 0.0047 0.0075 0.0186
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0046 0.0279
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0043 0.064
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0062 0.0111 0.1655
Entamoeba histolytica protein kinase rad3, putative 0.0018 0.0007 0.0064
Loa Loa (eye worm) hypothetical protein 0.0034 0.0046 0.0112
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0086 0.0524
Loa Loa (eye worm) hypothetical protein 0.0053 0.009 0.0222
Brugia malayi Cathepsin L-like precursor 0.0034 0.0046 0.0112
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0118 0.0118
Schistosoma mansoni hypothetical protein 0.0082 0.0159 0.0158
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0107 0.3162
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0013 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0046 0.0279
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0042 0.0064 0.0063
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0046 0.0429
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0132 0.1968
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0065
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0013 0.0374
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0107 0.1936
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0013 0.0229
Echinococcus multilocularis Ankyrin 0.0031 0.0038 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.009 0.0549
Entamoeba histolytica cysteine proteinase 1, putative 0.0026 0.0027 0.0249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0063 0.0384
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0013 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0027 0.0163
Entamoeba histolytica hypothetical protein 0.0023 0.0019 0.0172
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0027 0.0391
Echinococcus granulosus caspase 0.0123 0.0259 0.0258
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0083 0.0162 0.5008
Trichomonas vaginalis STE family protein kinase 0.0455 0.1052 0.6434
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0064 0.0063
Loa Loa (eye worm) phosphatidylinositol 3 0.0062 0.0111 0.0276
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0033 0.0043 0.1278
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0032 0.0041 0.0101
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0096 0.0194 0.3534
Echinococcus granulosus cathepsin l1 0.0034 0.0046 0.0045
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0033 0.0043 0.207
Trypanosoma brucei trypanothione reductase 0.0096 0.0194 0.2889
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0013 0.0229
Brugia malayi MH2 domain containing protein 0.0017 0.0004 0.0009
Trichomonas vaginalis mercuric reductase, putative 0.0033 0.0043 0.0266
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0308 0.0307
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0063 0.0384
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0013 0.0012
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0013 0.008
Leishmania major cathepsin L-like protease 0.0051 0.0086 0.1279
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0013 0.0012
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0013 0.018
Brugia malayi serine/threonine-protein kinase PAK 7 0.1692 0.4016 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0084 0.0516
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0041 0.0252
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0004 0.0003
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0021 0.0013 0.0229
Onchocerca volvulus 0.0021 0.0013 0.0077
Leishmania major cathepsin L-like protease 0.0195 0.0431 0.6427
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Echinococcus granulosus GPCR family 2 0.0064 0.0116 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0051 0.0309
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Entamoeba histolytica protein kinase, putative 0.0271 0.0612 0.5817
Schistosoma mansoni protein kinase 0.0455 0.1052 0.1052
Echinococcus multilocularis netrin receptor unc 5 0.0031 0.0038 0.0038
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.064
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0015 0.0001 0.0003
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0053 0.009 0.5536
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0083 0.1502
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0013 0.0031
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0013 0.0031
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0064 0.0943
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0041 0.0102
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0148 0.0317 0.1939
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0118 0.0118
Loa Loa (eye worm) thioredoxin reductase 0.0096 0.0194 0.0482
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.0162 0.4803
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.064
Trypanosoma cruzi metacaspase, putative 0.0047 0.0075 0.1112
Brugia malayi hypothetical protein 0.0049 0.0082 0.0202
Schistosoma mansoni coup transcription factor 0.0021 0.0013 0.0012
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0117 0.3683
Leishmania major cathepsin L-like protease 0.0195 0.0431 0.6427
Brugia malayi Death domain containing protein 0.0031 0.0038 0.0093
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Trypanosoma cruzi metacaspase, putative 0.0047 0.0075 0.1112
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0298 0.4441
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0053 0.009 0.0222
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0017 0.0016
Plasmodium falciparum glutathione reductase 0.0033 0.0043 0.1784
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0033 0.0043 0.064
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0027 0.0026
Trypanosoma cruzi metacaspase 5, putative 0.0047 0.0075 0.1112
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0013 0.0229
Plasmodium falciparum glutathione reductase 0.0096 0.0194 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0013 0.0031
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0042 0.0064 0.0601
Trypanosoma brucei metacaspase MCA2 0.0047 0.0075 0.1112
Entamoeba histolytica protein kinase, putative 0.0271 0.0612 0.5817
Plasmodium falciparum metacaspase 1 0.0047 0.0075 0.3511
Loa Loa (eye worm) hypothetical protein 0.0197 0.0435 0.1083
Loa Loa (eye worm) hypothetical protein 0.0071 0.0132 0.0329
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0107 0.0106
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0032 0.0041 0.0606
Echinococcus granulosus serine:threonine protein kinase PAK 1 0.0184 0.0404 0.0403
Trichomonas vaginalis inositol monophosphatase, putative 0.0148 0.0317 0.1939

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 7.31 Displacement of [3H]AVP from human V1A receptor expressed in CHO cells ChEMBL. 21458261

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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