Detailed information for compound 1510080

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 534.11 | Formula: C27H36ClN3O4S
  • H donors: 2 H acceptors: 3 LogP: 5.13 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1cc(C)c(c(c1C)C)S(=O)(=O)N[C@H](C(=O)N[C@@H]1C[C@H]2CC[C@@H](C1)N2C)Cc1ccc(cc1)Cl
  • InChi: 1S/C27H36ClN3O4S/c1-16-12-25(35-5)17(2)18(3)26(16)36(33,34)30-24(13-19-6-8-20(28)9-7-19)27(32)29-21-14-22-10-11-23(15-21)31(22)4/h6-9,12,21-24,30H,10-11,13-15H2,1-5H3,(H,29,32)/t21-,22-,23+,24-/m0/s1
  • InChiKey: ABECTNWXRXHWDP-XQUALCHDSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens arginine vasopressin receptor 1A Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.008 0.0079
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.064
Plasmodium vivax vivapain-2 0.0051 0.0086 0.4324
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0013 0.0012
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0064 0.0116 0.0115
Brugia malayi DKFZp564C0469 protein 0.002 0.0011 0.0025
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0013 0.0187
Schistosoma mansoni hypothetical protein 0.0266 0.06 0.0599
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0013 0.0374
Loa Loa (eye worm) hypothetical protein 0.0026 0.0027 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0449 0.104 0.6357
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0013 0.0229
Leishmania major phosphatidylinositol kinase related protein, putative 0.0021 0.0013 0.018
Plasmodium falciparum cysteine proteinase falcipain 1 0.0026 0.0027 0.0875
Loa Loa (eye worm) MH2 domain-containing protein 0.0248 0.0558 0.1387
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0017 0.0004 0.0009
Brugia malayi Niemann-Pick C1 protein precursor 0.0197 0.0435 0.1083
Brugia malayi Cathepsin L-like precursor 0.0051 0.0086 0.0213
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.064
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0079 0.0078
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.002 0.0011 0.0025
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.016 0.0396
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0053 0.009 0.1334
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0086 0.0815
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0075 0.2354
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0013 0.0012
Echinococcus multilocularis protein patched 0.0085 0.0166 0.0165
Echinococcus multilocularis expressed conserved protein 0.0185 0.0407 0.0406
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0033 0.0043 0.207
Toxoplasma gondii thioredoxin reductase 0.0096 0.0194 0.6115
Schistosoma mansoni serine/threonine protein kinase 0.0266 0.06 0.0599
Echinococcus multilocularis cathepsin L 0.0026 0.0027 0.0026
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0033 0.0043 0.1354
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0022 0.0054
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0004 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0013 0.0012
Trypanosoma cruzi cysteine protease, putative 0.0026 0.0027 0.0391
Schistosoma mansoni smad1 5 8 and 0.0017 0.0004 0.0003
Brugia malayi acetyltransferase, GNAT family protein 0.0148 0.0318 0.0789
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0013 0.0396
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0025
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0013 0.0132
Schistosoma mansoni ferritin 0.0018 0.0006 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0176 0.0175
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0013 0.0187
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0013 0.0187
Trypanosoma cruzi major cysteine proteinase, putative 0.0154 0.0331 0.4933
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0013 0.0012
Treponema pallidum DNA ligase (lig) 0.002 0.0011 0.0321
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0009
Plasmodium falciparum cysteine proteinase falcipain 3 0.0051 0.0086 0.4119
Brugia malayi ecdysteroid receptor 0.0021 0.0013 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0041 0.0252
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0083 0.0162 0.0161
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0013 0.0012
Brugia malayi topoisomerase 0.002 0.0011 0.0025
Schistosoma mansoni hypothetical protein 0.0431 0.0996 0.0995
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.002 0.0011 0.0161
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0027 0.0249
Schistosoma mansoni protein kinase 0.0455 0.1052 0.1052
Echinococcus multilocularis geminin 0.0165 0.0359 0.0358
Schistosoma mansoni smad1 5 8 and 0.0017 0.0004 0.0003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0079 0.0078
Loa Loa (eye worm) hypothetical protein 0.0089 0.0176 0.0436
Onchocerca volvulus 0.0071 0.0132 0.0807
Echinococcus granulosus nuclear factor of activated T cells 5 0.0304 0.0693 0.0692
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0059 0.2629
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0111 0.0682
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0013 0.0229
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0079 0.0078
Brugia malayi Inositol-1 0.0148 0.0317 0.0789
Loa Loa (eye worm) fibroinase 0.0051 0.0086 0.0213
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0063 0.0931
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0132 0.028 0.5103
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0013 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0084 0.0516
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0201 0.0445 0.1107
Brugia malayi hypothetical protein 0.002 0.0011 0.0025
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0132 0.3933
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0013 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0012 0.0075
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0033 0.0043 0.1278
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0013 0.0012
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0062 0.0111 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0075 0.0459
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0062 0.0111 0.0111
Schistosoma mansoni cpg binding protein 0.0032 0.004 0.004
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0031 0.0038 0.0038
Schistosoma mansoni niemann-pick C1 (NPC1) 0.02 0.0443 0.0442
Leishmania major trypanothione reductase 0.0096 0.0194 0.2889
Entamoeba histolytica hypothetical protein 0.0266 0.06 0.5698
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0082 0.1211
Giardia lamblia Kinase, STE STE20 0.0455 0.1052 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.008 0.0198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0111 0.0682
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0304 0.0693 0.0692
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0041 0.0606
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0132 0.3933
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0189 0.0416 0.1035
Plasmodium vivax thioredoxin reductase, putative 0.0096 0.0194 1
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0013 0.0229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0111 0.0682
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0032 0.1149
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0027 0.0249
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Entamoeba histolytica hypothetical protein 0.0039 0.0057 0.0533
Echinococcus granulosus ubiquitin specific protease 41 0.0042 0.0064 0.0063
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.1427 0.338 0.3379
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0004 0.0003
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0086 0.0086
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0132 0.1254
Loa Loa (eye worm) hypothetical protein 0.0149 0.0319 0.0794
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0455 0.1052 0.1052
Plasmodium vivax SET domain protein, putative 0.0089 0.0176 0.9024
Onchocerca volvulus Netrin receptor homolog 0.0031 0.0038 0.0229
Toxoplasma gondii target of rapamycin (TOR), putative 0.005 0.0084 0.2647
Trichomonas vaginalis ferritin, putative 0.0018 0.0006 0.0035
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0178 0.0391 0.5821
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0085 0.0166 0.0166
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0013 0.0012
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0013 0.0012
Trichomonas vaginalis STE family protein kinase 0.0455 0.1052 0.6434
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0027 0.0249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0061 0.0373
Leishmania major cathepsin L-like protease 0.0051 0.0086 0.1279
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.002 0.0011 0.0302
Echinococcus granulosus histone lysine methyltransferase setb 0.0089 0.0176 0.0175
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0013 0.0012
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0201 0.0445 0.1107
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0033 0.0043 0.064
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0025
Schistosoma mansoni ankyrin 23/unc44 0.0031 0.0038 0.0038
Echinococcus granulosus cysteine protease 0.0026 0.0027 0.0026
Schistosoma mansoni inositol monophosphatase 0.0148 0.0317 0.0317
Entamoeba histolytica hypothetical protein 0.002 0.0011 0.0096
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0013 0.0374
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0148 0.0317 0.4725
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.009 0.0549
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0132 0.0329
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0013 0.0031
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0083 0.1502
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Brugia malayi Cathepsin L-like precursor 0.0051 0.0086 0.0213
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0086 0.0815
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0064 0.0116 0.0115
Schistosoma mansoni smad 0.0017 0.0004 0.0003
Onchocerca volvulus 0.0034 0.0046 0.0276
Echinococcus granulosus PAK box P21 Rho binding 0.0266 0.06 0.0599
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0051 0.0086 0.4119
Schistosoma mansoni cathepsin s 0.0017 0.0004 0.0004
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0086 0.0086
Trichomonas vaginalis STE family protein kinase 0.0455 0.1052 0.6434
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0017 0.0016
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.0013 0.0374
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.022 0.049 0.8928
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0019 0.0415
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0189 0.0416 0.1035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0045
Plasmodium vivax replication factor C subunit 1, putative 0.002 0.0011 0.0348
Loa Loa (eye worm) hypothetical protein 0.0474 0.1099 0.2734
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.009 0.0549
Echinococcus multilocularis protein dispatched 1 0.0097 0.0195 0.0194
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0019 0.057
Brugia malayi Cathepsin L-like precursor 0.0051 0.0086 0.0213
Schistosoma mansoni apoferritin-2 0.0018 0.0006 0.0005
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Toxoplasma gondii cathepsin CPL 0.0051 0.0086 0.2707
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0063 0.0384
Onchocerca volvulus 0.0051 0.0086 0.0524
Echinococcus multilocularis caspase 8 0.0047 0.0075 0.0075
Echinococcus multilocularis thioredoxin glutathione reductase 0.0096 0.0194 0.0194
Brugia malayi hypothetical protein 0.0032 0.004 0.0098
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0019 0.1121
Schistosoma mansoni ferritin 0.0018 0.0006 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0007 0.0045
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0013 0.0374
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0189 0.0416 0.1035
Echinococcus granulosus Smad4 0.0017 0.0004 0.0003
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0118 0.0118
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0019 0.057
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0004 0.0053
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0047 0.0075 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0013 0.0031
Giardia lamblia NADH oxidase lateral transfer candidate 0.0033 0.0043 0.0408
Trichomonas vaginalis replication factor C large subunit, putative 0.002 0.0011 0.0065
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0013 0.0012
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0068 0.0413
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0013 0.0031
Brugia malayi glutathione reductase 0.0096 0.0194 0.0482
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0071 0.0132 0.2408
Toxoplasma gondii hypothetical protein 0.0048 0.0078 0.2432
Loa Loa (eye worm) hypothetical protein 0.009 0.0179 0.0445
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0013 0.0187
Schistosoma mansoni hypothetical protein 0.0064 0.0116 0.0115
Loa Loa (eye worm) hypothetical protein 0.0042 0.0064 0.0157
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0062 0.0111 0.1655
Echinococcus granulosus Niemann Pick C1 protein 0.0282 0.0638 0.0637
Brugia malayi hypothetical protein 0.0149 0.0319 0.0794
Echinococcus granulosus cpg binding protein 0.0032 0.004 0.004
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0031 0.0038 0.0038
Onchocerca volvulus 0.0051 0.0086 0.0524
Loa Loa (eye worm) transcription factor SMAD2 0.0248 0.0558 0.1387
Trypanosoma cruzi cysteine peptidase, putative 0.0051 0.0086 0.1279
Brugia malayi Cell death protein 3 precursor 0.009 0.0179 0.0445
Schistosoma mansoni hypothetical protein 0.0064 0.0116 0.0115
Entamoeba histolytica cysteine protease, putative 0.0051 0.0086 0.0815
Leishmania major cathepsin L-like protease 0.0195 0.0431 0.6427
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0013 0.0374
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0085 0.1255
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0013 0.0075
Onchocerca volvulus 0.0043 0.0067 0.0409
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0018 0.0007 0.0101
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0107 0.3162
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.064
Loa Loa (eye worm) phosphatidylinositol 3 0.0032 0.0041 0.0101
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.1427 0.338 0.3379
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0019 0.0765
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0018 0.0006 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0013 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Echinococcus granulosus caspase 3 0.0077 0.0147 0.0146
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0068 0.3341
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0019 0.0538
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0062 0.0111 0.1055
Echinococcus granulosus apoptotic protease activating factor 1 0.0043 0.0067 0.0067
Plasmodium falciparum metacaspase-like protein 0.0047 0.0075 0.3511
Brugia malayi Thioredoxin reductase 0.0096 0.0194 0.0482
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0013 0.0229
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0068 0.2117
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0118 0.0293
Schistosoma mansoni caspase-7 (C14 family) 0.009 0.0179 0.0179
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Trypanosoma cruzi p21-activated kinase 3, putative 0.0189 0.0416 0.6199
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.0671 1
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Onchocerca volvulus 0.002 0.0011 0.0062
Echinococcus multilocularis PAK box P21 Rho binding 0.0266 0.06 0.0599
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0079 0.0078
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0075 0.2354
Brugia malayi P21-Rho-binding domain containing protein 0.0266 0.06 0.1493
Brugia malayi cathepsin L-like precursor 0.0034 0.0046 0.0112
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0029 0.0034 0.0498
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0013 0.0187
Schistosoma mansoni ferritin light chain 0.0018 0.0006 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0013 0.0031
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0054 0.0093 0.1695
Echinococcus multilocularis smad 0.0017 0.0004 0.0003
Trypanosoma cruzi metacaspase, putative 0.0047 0.0075 0.1112
Schistosoma mansoni ferritin 0.0018 0.0006 0.0005
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0132 0.028 0.5103
Echinococcus granulosus expressed protein 0.0018 0.0006 0.0005
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0013 0.0031
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0079 0.0078
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0033 0.0043 0.064
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0017
Echinococcus granulosus caspase 2 0.009 0.0179 0.0179
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0019 0.027
Echinococcus granulosus Niemann Pick C1 protein 0.0197 0.0435 0.0435
Echinococcus granulosus smad 0.0017 0.0004 0.0003
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0063 0.0931
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0295 0.0671 1
Plasmodium falciparum thioredoxin reductase 0.0033 0.0043 0.1784
Echinococcus granulosus neural Wiskott Aldrich syndrome protein 0.0266 0.06 0.0599
Brugia malayi MH1 domain containing protein 0.0017 0.0004 0.0009
Echinococcus granulosus cathepsin L cysteine protease 0.0026 0.0027 0.0026
Echinococcus granulosus ferritin 0.0018 0.0006 0.0005
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0027 0.0391
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0089 0.0176 0.0175
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0071 0.0132 0.3933
Mycobacterium tuberculosis Probable oxidoreductase 0.0244 0.0548 1
Brugia malayi Cathepsin L-like precursor 0.0017 0.0004 0.0009
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0029 0.0032 0.057
Toxoplasma gondii ATPase, AAA family protein 0.002 0.0011 0.032
Brugia malayi Cathepsin L-like precursor 0.0051 0.0086 0.0213
Brugia malayi RNA binding protein 0.0065 0.0118 0.0293
Echinococcus granulosus expressed conserved protein 0.0185 0.0407 0.0406
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0013 0.008
Entamoeba histolytica hypothetical protein 0.0039 0.0057 0.0533
Echinococcus multilocularis expressed protein 0.0018 0.0006 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0086 0.0527
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0013 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0166 0.1015
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.009 0.2659
Trypanosoma cruzi cruzipain precursor, putative 0.0195 0.0431 0.6427
Schistosoma mansoni hypothetical protein 0.0082 0.0159 0.0158
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.022 0.049 0.8928
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0083 0.0162 0.2941
Chlamydia trachomatis DNA ligase 0.002 0.0011 0.0629
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0042 0.0064 0.0601
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0004 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0041 0.0252
Onchocerca volvulus 0.0082 0.016 0.0972
Trypanosoma brucei PAB1-binding protein , putative 0.0049 0.0082 0.1211
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0004 0.0003
Mycobacterium ulcerans bacterioferritin BfrA 0.0018 0.0006 0.0153
Loa Loa (eye worm) hypothetical protein 0.0449 0.104 0.2588
Schistosoma mansoni hypothetical protein 0.0097 0.0195 0.0194
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0013 0.0031
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0064 0.0116 0.0115
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0176 0.0175
Echinococcus granulosus replication factor c subunit 1 0.002 0.0011 0.001
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0062 0.0111 0.1655
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0086 0.0213
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0013 0.0229
Mycobacterium tuberculosis Probable dehydrogenase 0.022 0.049 0.8928
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0086 0.0086
Schistosoma mansoni tyrosine kinase 0.0266 0.06 0.0599
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0064 0.039
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0064 0.0943
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.064
Schistosoma mansoni inositol monophosphatase 0.0148 0.0317 0.0317
Schistosoma mansoni topbp1 0.002 0.0011 0.001
Echinococcus granulosus thioredoxin glutathione reductase 0.0096 0.0194 0.0194
Brugia malayi Cathepsin L-like precursor 0.0051 0.0086 0.0213
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0013 0.0012
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0079 0.0195
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0125 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Brugia malayi nuclear hormone receptor 0.0021 0.0013 0.0031
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Schistosoma mansoni hypothetical protein 0.0137 0.0293 0.0292
Brugia malayi Muscleblind-like protein 0.0152 0.0327 0.0814
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0019 0.027
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0148 0.0317 0.9439
Loa Loa (eye worm) RNA binding protein 0.0065 0.0118 0.0293
Onchocerca volvulus 0.0051 0.0086 0.0524
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0057 0.0056
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0013 0.0475
Onchocerca volvulus 0.0049 0.008 0.0485
Plasmodium vivax metacaspase 1, putative 0.0047 0.0075 0.3736
Trypanosoma cruzi FHA domain containing protein, putative 0.002 0.0011 0.0151
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0013 0.0031
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0013 0.0187
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0033 0.0043 0.064
Echinococcus granulosus cathepsin L cysteine proteinase 0.0051 0.0086 0.0086
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0043 0.1212
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0013 0.0031
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0013 0.0031
Brugia malayi Calcitonin receptor-like protein seb-1 0.0201 0.0445 0.1107
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0033 0.0043 0.1784
Mycobacterium tuberculosis Probable reductase 0.022 0.049 0.8928
Brugia malayi Cathepsin L-like precursor 0.0034 0.0046 0.0112
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0013 0.0031
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0079 0.0078
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0013 0.0396
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0013 0.0031
Echinococcus granulosus Ankyrin 0.0031 0.0038 0.0038
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.0195 0.0484
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0013 0.0187
Trypanosoma brucei metacaspase 0.0047 0.0075 0.1112
Brugia malayi Pre-SET motif family protein 0.0089 0.0176 0.0436
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Loa Loa (eye worm) hypothetical protein 0.0201 0.0445 0.1107
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Schistosoma mansoni wiskott-aldrich syndrome protein 0.0266 0.06 0.0599
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0071 0.0132 0.3933
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0123 0.0259 0.0258
Trichomonas vaginalis STE family protein kinase 0.0271 0.0612 0.3744
Plasmodium vivax vivapain-2 0.0051 0.0086 0.4324
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0614 0.1433 0.3567
Onchocerca volvulus 0.0051 0.0086 0.0524
Brugia malayi hypothetical protein 0.0043 0.0067 0.0167
Onchocerca volvulus 0.0051 0.0086 0.0524
Echinococcus multilocularis tumor protein p63 0.0332 0.0759 0.0758
Brugia malayi TAR-binding protein 0.0065 0.0118 0.0293
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0018 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0089 0.0176 0.0175
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0455 0.1052 0.1052
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0047 0.0075 0.0075
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.0013 0.0374
Loa Loa (eye worm) hypothetical protein 0.0051 0.0086 0.0213
Brugia malayi P21-Rho-binding domain containing protein 0.0266 0.06 0.1493
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.0336 0.6123
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0013 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0068 0.0417
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0148 0.0318 0.0317
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0013 0.0012
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0011 0.0065
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0013 0.0119
Toxoplasma gondii FATC domain-containing protein 0.0033 0.0041 0.1292
Schistosoma mansoni hypothetical protein 0.0022 0.0017 0.0016
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0244 0.0548 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Leishmania major hypothetical protein, conserved 0.0049 0.0082 0.1211
Onchocerca volvulus 0.003 0.0036 0.0216
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Loa Loa (eye worm) hypothetical protein 0.0152 0.0327 0.0814
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0027 0.0391
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0013 0.0374
Schistosoma mansoni hypothetical protein 0.0064 0.0116 0.0115
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0031 0.0038 0.0038
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0083 0.0162 0.0161
Brugia malayi MH2 domain containing protein 0.0248 0.0558 0.1387
Loa Loa (eye worm) hypothetical protein 0.0083 0.0162 0.0401
Giardia lamblia GTOR 0.0062 0.0111 0.1055
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0033 0.0043 0.2661
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.022 0.049 0.8928
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0089 0.0176 0.0175
Echinococcus granulosus survival motor neuron protein 1 0.0474 0.1099 0.1098
Echinococcus multilocularis Niemann Pick C1 protein 0.0197 0.0435 0.0435
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0032 0.0041 0.0041
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0013 0.0031
Loa Loa (eye worm) hypothetical protein 0.0043 0.0067 0.0167
Entamoeba histolytica protein kinase, putative 0.0271 0.0612 0.5817
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0019 0.0829
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0011 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0065
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0079 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Loa Loa (eye worm) Smad1 0.0017 0.0004 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0084 0.0516
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0083 0.1502
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0051 0.0309
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0107 0.0106
Schistosoma mansoni hypothetical protein 0.0266 0.06 0.0599
Brugia malayi MH2 domain containing protein 0.0017 0.0004 0.0009
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0057 0.0056
Entamoeba histolytica hypothetical protein 0.0039 0.0057 0.0533
Onchocerca volvulus 0.0089 0.0176 0.107
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0018 0.0007 0.0007
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0053 0.009 0.1334
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0041 0.0252
Plasmodium vivax vivapain-1 0.0026 0.0027 0.1192
Brugia malayi latrophilin 2 splice variant baaae 0.0137 0.0293 0.0728
Echinococcus multilocularis Smad4 0.0017 0.0004 0.0003
Schistosoma mansoni cpg binding protein 0.0032 0.004 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0063 0.0384
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0063 0.0931
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.022 0.049 0.8928
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0013 0.0031
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0244 0.0548 1
Brugia malayi hypothetical protein 0.002 0.0011 0.0025
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0455 0.1052 0.1052
Echinococcus multilocularis replication factor c subunit 1 0.002 0.0011 0.001
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0089 0.0176 0.5529
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0083 0.0162 0.8291
Onchocerca volvulus 0.0051 0.0086 0.0524
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.0013 0.0374
Plasmodium falciparum thioredoxin reductase 0.0096 0.0194 1
Loa Loa (eye worm) inositol-1 0.0148 0.0317 0.0789
Plasmodium vivax unspecified product 0.0026 0.0027 0.1192
Echinococcus multilocularis cpg binding protein 0.0032 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0064 0.0116 0.0287
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0064 0.0063
Echinococcus multilocularis survival motor neuron protein 1 0.0474 0.1099 0.1098
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0075 0.0459
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0064 0.0943
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.016 0.0159
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0059 0.0555
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Schistosoma mansoni hypothetical protein 0.0266 0.06 0.0599
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0118 0.0118
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative 0.0015 0.0001 0.0003
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0013 0.0187
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0062 0.0111 0.1055
Echinococcus multilocularis muscleblind protein 0.0152 0.0327 0.0327
Trypanosoma cruzi cysteine peptidase, putative 0.0195 0.0431 0.6427
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0033 0.0043 0.1278
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0068 0.2117
Schistosoma mansoni caspase-3 (C14 family) 0.0123 0.0259 0.0258
Toxoplasma gondii NADPH-glutathione reductase 0.0033 0.0043 0.1354
Schistosoma mansoni ferritin 0.0018 0.0006 0.0005
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0068 0.0067
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0027 0.0026
Schistosoma mansoni protein kinase 0.0266 0.06 0.0599
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0025
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0013 0.0374
Loa Loa (eye worm) acetyltransferase 0.0148 0.0318 0.0789
Schistosoma mansoni hypothetical protein 0.0082 0.0159 0.0158
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0033 0.0043 0.0043
Brugia malayi Protein kinase domain 0.0455 0.1052 0.2619
Echinococcus multilocularis apoptotic protease activating factor 1 0.0043 0.0067 0.0067
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.0162 1
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.0022 0.0315
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0013 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0063 0.0384
Echinococcus multilocularis Ankyrin 0.0031 0.0038 0.0038
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0013 0.0229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.009 0.0549
Entamoeba histolytica cysteine proteinase 1, putative 0.0026 0.0027 0.0249
Echinococcus granulosus caspase 0.0123 0.0259 0.0258
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0027 0.0391
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0083 0.0162 0.5008
Entamoeba histolytica hypothetical protein 0.0023 0.0019 0.0172
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0027 0.0163
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0042 0.0064 0.0063
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0013 0.0374
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0107 0.1936
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0132 0.1968
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0046 0.0429
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0065
Brugia malayi MH2 domain containing protein 0.0017 0.0004 0.0009
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0096 0.0194 0.3534
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0033 0.0043 0.207
Echinococcus granulosus cathepsin l1 0.0034 0.0046 0.0045
Trypanosoma brucei trypanothione reductase 0.0096 0.0194 0.2889
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0013 0.0229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0063 0.0384
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0308 0.0307
Trichomonas vaginalis mercuric reductase, putative 0.0033 0.0043 0.0266
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0025
Loa Loa (eye worm) phosphatidylinositol 3 0.0062 0.0111 0.0276
Trichomonas vaginalis STE family protein kinase 0.0455 0.1052 0.6434
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0064 0.0063
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0033 0.0043 0.1278
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0032 0.0041 0.0101
Plasmodium vivax acyl-CoA synthetase, putative 0.0053 0.009 0.4507
Trypanosoma cruzi metacaspase 5, putative 0.0047 0.0075 0.1112
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0013 0.0229
Leishmania major cathepsin L-like protease 0.0051 0.0086 0.1279
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0013 0.0229
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0083 0.1502
Loa Loa (eye worm) latrophilin receptor protein 2 0.0064 0.0116 0.0287
Brugia malayi hypothetical protein 0.0039 0.0057 0.014
Trypanosoma cruzi cysteine peptidase, putative 0.0195 0.0431 0.6427
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Brugia malayi MH1 domain containing protein 0.0017 0.0004 0.0009
Entamoeba histolytica hypothetical protein 0.0033 0.0041 0.0389
Brugia malayi nuclear receptor NHR-88 0.0021 0.0013 0.0031
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0082 0.3871
Brugia malayi Cathepsin L-like precursor 0.0034 0.0046 0.0112
Loa Loa (eye worm) hypothetical protein 0.0053 0.009 0.0222
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0118 0.0118
Entamoeba histolytica protein kinase rad3, putative 0.0018 0.0007 0.0064
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0086 0.0524
Loa Loa (eye worm) hypothetical protein 0.0034 0.0046 0.0112
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0107 0.3162
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0013 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0046 0.0279
Schistosoma mansoni hypothetical protein 0.0082 0.0159 0.0158
Loa Loa (eye worm) hypothetical protein 0.0047 0.0075 0.0186
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0013 0.0012
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0036 0.0088
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0046 0.0279
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0062 0.0111 0.1655
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0043 0.064
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0009
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0053 0.009 0.0222
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0298 0.4441
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0027 0.0026
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0033 0.0043 0.064
Plasmodium falciparum glutathione reductase 0.0033 0.0043 0.1784
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0117 0.3683
Schistosoma mansoni coup transcription factor 0.0021 0.0013 0.0012
Brugia malayi hypothetical protein 0.0049 0.0082 0.0202
Trypanosoma cruzi metacaspase, putative 0.0047 0.0075 0.1112
Trypanosoma cruzi metacaspase, putative 0.0047 0.0075 0.1112
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Leishmania major cathepsin L-like protease 0.0195 0.0431 0.6427
Brugia malayi Death domain containing protein 0.0031 0.0038 0.0093
Echinococcus granulosus serine:threonine protein kinase PAK 1 0.0184 0.0404 0.0403
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0032 0.0041 0.0606
Trichomonas vaginalis inositol monophosphatase, putative 0.0148 0.0317 0.1939
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0013 0.0031
Plasmodium falciparum glutathione reductase 0.0096 0.0194 1
Trypanosoma cruzi metacaspase 5, putative 0.0047 0.0075 0.1112
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0013 0.0229
Loa Loa (eye worm) hypothetical protein 0.0071 0.0132 0.0329
Loa Loa (eye worm) hypothetical protein 0.0197 0.0435 0.1083
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0107 0.0106
Trypanosoma brucei metacaspase MCA2 0.0047 0.0075 0.1112
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0042 0.0064 0.0601
Plasmodium falciparum metacaspase 1 0.0047 0.0075 0.3511
Entamoeba histolytica protein kinase, putative 0.0271 0.0612 0.5817
Leishmania major cathepsin L-like protease 0.0195 0.0431 0.6427
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Loa Loa (eye worm) hypothetical protein 0.0017 0.0004 0.0009
Onchocerca volvulus 0.0021 0.0013 0.0077
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0021 0.0013 0.0229
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0004 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0041 0.0252
Entamoeba histolytica protein kinase, putative 0.0271 0.0612 0.5817
Schistosoma mansoni protein kinase 0.0455 0.1052 0.1052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Echinococcus granulosus GPCR family 2 0.0064 0.0116 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0051 0.0309
Leishmania major cathepsin L-like protease 0.0051 0.0086 0.1279
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0013 0.0012
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0013 0.0012
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0013 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0084 0.0516
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0013 0.0012
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0013 0.018
Brugia malayi serine/threonine-protein kinase PAK 7 0.1692 0.4016 1
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0064 0.0943
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0041 0.0102
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.064
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.0162 0.4803
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0118 0.0118
Loa Loa (eye worm) thioredoxin reductase 0.0096 0.0194 0.0482
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0148 0.0317 0.1939
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.064
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0053 0.009 0.5536
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0015 0.0001 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0083 0.1502
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0013 0.0031
Echinococcus multilocularis netrin receptor unc 5 0.0031 0.0038 0.0038
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0013 0.0031
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Brugia malayi CXXC zinc finger family protein 0.003 0.0036 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0013 0.0031
Brugia malayi Protein kinase domain containing protein 0.0036 0.0051 0.0125
Brugia malayi WH1 domain containing protein 0.0266 0.06 0.1493
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0086 0.0213
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.002 0.0011 0.0185
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0064 0.0063
Loa Loa (eye worm) hypothetical protein 0.0034 0.0046 0.0112
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0054 0.0093 0.1695
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0013 0.0229
Echinococcus multilocularis inositol monophosphatase 1 0.0148 0.0317 0.0317
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0042 0.0064 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0086 0.0527
Trypanosoma cruzi cysteine peptidase, putative 0.0026 0.0027 0.0391
Echinococcus multilocularis sterol regulatory element binding protein 0.0085 0.0166 0.0165
Toxoplasma gondii non-specific serine/threonine protein kinase 0.002 0.0012 0.0371
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0013 0.0075
Loa Loa (eye worm) hypothetical protein 0.0053 0.009 0.0222
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0013 0.0031
Trichomonas vaginalis STE family protein kinase 0.0455 0.1052 0.6434
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0062 0.0111 0.1655
Leishmania major mitochondrial DNA polymerase beta 0.0295 0.0671 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0013 0.0012
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0027 0.0065
Loa Loa (eye worm) hypothetical protein 0.0034 0.0046 0.0112
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0033 0.0043 0.0043
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0189 0.0416 0.6199
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0084 0.0516
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0197 0.0435 0.4134
Brugia malayi hypothetical protein 0.0474 0.1099 0.2734
Loa Loa (eye worm) hypothetical protein 0.0082 0.016 0.0396
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0132 0.3933
Schistosoma mansoni hypothetical protein 0.0165 0.0359 0.0358
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.0162 0.4803
Echinococcus granulosus muscleblind protein 0.0152 0.0327 0.0327
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0082 0.3871
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0022 0.0054
Onchocerca volvulus 0.0149 0.0319 0.195
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0027 0.0388
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0079 0.0195
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0062 0.0111 0.0276
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0013 0.0012
Entamoeba histolytica cysteine proteinase 2 0.0026 0.0027 0.0249
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0082 0.1211
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0018 0.0007 0.0064
Loa Loa (eye worm) ctsf protein 0.0051 0.0086 0.0213
Echinococcus multilocularis caspase 2 0.009 0.0179 0.0179
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0132 0.1968
Trypanosoma cruzi metacaspase, putative 0.0047 0.0075 0.1112
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0019 0.033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Leishmania major cathepsin L-like protease 0.0051 0.0086 0.1279
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0013 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0064 0.039
Loa Loa (eye worm) glutathione reductase 0.0096 0.0194 0.0482
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.0298 0.4441
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0013 0.0031
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0004 0.0009
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0064 0.039
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0148 0.0318 0.0317
Echinococcus multilocularis caspase 0.0123 0.0259 0.0258
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0062 0.0111 0.1655
Echinococcus granulosus cathepsin l1 0.0051 0.0086 0.0086
Toxoplasma gondii LsmAD domain-containing protein 0.0049 0.0082 0.2563
Schistosoma mansoni hypothetical protein 0.0082 0.0159 0.0158
Mycobacterium ulcerans bacterioferritin BfrB 0.0018 0.0006 0.0153
Echinococcus multilocularis cysteine protease 0.0051 0.0086 0.0086
Onchocerca volvulus 0.0021 0.0013 0.0077
Onchocerca volvulus Cell death protein 3 homolog 0.009 0.0179 0.1091
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Schistosoma mansoni netrin receptor unc5 0.0031 0.0038 0.0038
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0071 0.0132 0.3933
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0062 0.0111 0.0111
Brugia malayi Uncoordinated protein 44 0.0031 0.0038 0.0093
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0132 0.2408
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0019 0.0538
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0075 0.0459
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0132 0.1968
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0065
Trichomonas vaginalis inositol monophosphatase, putative 0.0015 0.0001 0.0003
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0013 0.0229
Echinococcus multilocularis PAK box P21 Rho binding 0.0271 0.0612 0.0612
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0132 0.0329
Leishmania major phosphatidylinositol 3-kinase, putative 0.0032 0.0041 0.0606
Brugia malayi cathepsin F-like cysteine proteinase 0.0017 0.0004 0.0009
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0086 0.0086
Brugia malayi Latrophilin receptor protein 2 0.0064 0.0116 0.0287
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.0013 0.0374
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0059 0.0555
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0027 0.0249
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0013 0.0031
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0189 0.0416 0.2543
Loa Loa (eye worm) oxidoreductase 0.0021 0.0013 0.0031
Schistosoma mansoni apoferritin-2 0.0018 0.0006 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0013 0.0031
Echinococcus granulosus serine protein kinase ATM 0.0033 0.0041 0.0041
Echinococcus multilocularis ferritin 0.0018 0.0006 0.0005
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0013 0.0012
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Onchocerca volvulus 0.0021 0.0013 0.0077
Plasmodium falciparum acyl-CoA synthetase 0.0053 0.009 0.431
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0057 0.0056
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0013 0.0012
Leishmania major cathepsin L-like protease 0.0051 0.0086 0.1279
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0148 0.0317 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0013 0.0031
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0033 0.0041 0.0041
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0107 0.1583
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0043 0.064
Echinococcus multilocularis cysteine protease 0.0051 0.0086 0.0086
Trypanosoma cruzi target of rapamycin kinase 3 0.0053 0.009 0.1334
Brugia malayi Pax transcription activation domain interacting protein 0.002 0.0011 0.0025
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0063 0.0931
Echinococcus granulosus cathepsin L 0.0026 0.0027 0.0026
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0027 0.0065
Schistosoma mansoni topbp1 0.002 0.0011 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.064
Echinococcus multilocularis dnaJ subfamily B 0.0431 0.0996 0.0995
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0084 0.0516
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0013 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0068 0.0417
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0075 0.0459
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0033 0.0043 0.1784
Onchocerca volvulus 0.0051 0.0086 0.0524
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0085 0.0166 0.0412
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.0038 0.0093
Loa Loa (eye worm) hypothetical protein 0.0152 0.0327 0.0814
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0027 0.0391
Schistosoma mansoni Smad4 0.0017 0.0004 0.0003
Trypanosoma cruzi cruzipain precursor, putative 0.0017 0.0004 0.0053
Schistosoma mansoni hypothetical protein 0.0165 0.0359 0.0358
Loa Loa (eye worm) hypothetical protein 0.0071 0.0132 0.0329
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0006 0.0103
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0027 0.0163
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0084 0.0516
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Plasmodium vivax hypothetical protein, conserved 0.0047 0.0075 0.3736
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0065
Onchocerca volvulus 0.0021 0.0013 0.0077
Schistosoma mansoni smad1 5 8 and 0.0017 0.0004 0.0003
Trichomonas vaginalis glutathione reductase, putative 0.0033 0.0043 0.0266
Trypanosoma brucei Metacaspase-4 0.0047 0.0075 0.1112
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0455 0.1052 0.1052
Echinococcus granulosus dnaJ subfamily B 0.0431 0.0996 0.0995
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0298 0.4441
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0011 0.0151
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0071 0.0132 0.3933
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0051 0.0309
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0018 0.0006 0.0094
Loa Loa (eye worm) hypothetical protein 0.0085 0.0166 0.0412
Schistosoma mansoni hypothetical protein 0.0031 0.0038 0.0038
Brugia malayi CHE-14 protein 0.0085 0.0166 0.0412
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0013 0.0012
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Trypanosoma cruzi trypanothione reductase, putative 0.0096 0.0194 0.2889
Entamoeba histolytica acyl-coA synthetase, putative 0.0071 0.0132 0.1254
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0295 0.0671 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0027 0.0026
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0033 0.0043 0.0783
Echinococcus multilocularis Niemann Pick C1 protein 0.0282 0.0638 0.0637
Trypanosoma cruzi cysteine peptidase, putative 0.0195 0.0431 0.6427
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0244 0.0548 1
Echinococcus granulosus death domain containing protein 0.0031 0.0038 0.0038
Loa Loa (eye worm) P21-Rho-binding domain-containing protein 0.0266 0.06 0.1493
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0013 0.0374
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Echinococcus granulosus geminin 0.0165 0.0359 0.0358
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0013 0.0031
Entamoeba histolytica hypothetical protein 0.0039 0.0057 0.0533
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0078 0.0474
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0011 0.0151
Loa Loa (eye worm) hypothetical protein 0.0053 0.009 0.0222
Schistosoma mansoni hypothetical protein 0.0064 0.0116 0.0115
Echinococcus multilocularis neural Wiskott Aldrich syndrome protein 0.0266 0.06 0.0599
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0013 0.0374
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0063 0.0384
Echinococcus granulosus Protein patched homolog 1 0.0085 0.0166 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.009 0.0549
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0132 0.1254
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0042 0.0064 0.0157
Schistosoma mansoni fkbp-rapamycin associated protein 0.0018 0.0007 0.0007
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0018 0.0006 0.0094
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0071 0.0132 0.2408
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0075 0.0459
Echinococcus multilocularis peptidase Clp (S14 family) 0.0054 0.0093 0.0093
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0455 0.1052 0.1052
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0011 0.0065
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0013 0.0013
Echinococcus multilocularis nibrin 0.002 0.0011 0.001
Schistosoma mansoni patched 1 0.0085 0.0166 0.0165
Brugia malayi steroid hormone receptor 0.0021 0.0013 0.0031
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0013 0.0396
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0011 0.0065
Entamoeba histolytica protein kinase, putative 0.0455 0.1052 1
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0032 0.0041 0.0041
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0038 0.0093
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0148 0.0317 0.301
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0046 0.0045
Echinococcus granulosus netrin receptor unc 5 0.0031 0.0038 0.0038
Mycobacterium ulcerans hypothetical protein 0.0156 0.0336 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0075 0.2354
Brugia malayi Smad1 0.0017 0.0004 0.0009
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0043 0.064
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0032 0.1672
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0013 0.0075
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.016 0.0159
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0013 0.0012
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0148 0.0317 0.4725
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0041 0.0606
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0075 0.0459
Onchocerca volvulus Cathepsin F homolog 0.0051 0.0086 0.0524
Plasmodium vivax vivapain-3 0.0026 0.0027 0.1192
Echinococcus granulosus inositol monophosphatase 1 0.0148 0.0317 0.0317
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0132 0.0329
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0054 0.0093 0.1695
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0013 0.0012
Echinococcus granulosus caspase 8 0.0047 0.0075 0.0075
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.1692 0.4016 1
Echinococcus granulosus peptidase Clp S14 family 0.0054 0.0093 0.0093
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0118 0.0293
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0041 0.0254
Schistosoma mansoni DNA ligase IV 0.002 0.0011 0.001
Echinococcus granulosus sterol regulatory element binding protein 0.0085 0.0166 0.0165
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0011 0.0151
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0033 0.0043 0.0107
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2478 0.5897 0.5897
Schistosoma mansoni caspase-7 (C14 family) 0.0123 0.0259 0.0258
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0013 0.0031
Brugia malayi Cathepsin L-like precursor 0.0051 0.0086 0.0213
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0093
Toxoplasma gondii hypothetical protein 0.0029 0.0032 0.0986
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0013 0.0031
Schistosoma mansoni peptidase Clp (S14 family) 0.0083 0.0162 0.0161
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0032 0.0041 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0063 0.0384
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.0013 0.0374
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0013 0.0374
Onchocerca volvulus 0.0021 0.0013 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0075 0.0459
Echinococcus granulosus nibrin 0.002 0.0011 0.001
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0083 0.0162 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0053 0.009 0.1628
Schistosoma mansoni hypothetical protein 0.0039 0.0057 0.0056
Schistosoma mansoni hypothetical protein 0.0043 0.0067 0.0067
Mycobacterium ulcerans hypothetical protein 0.0071 0.0132 0.3933
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0019 0.0432
Echinococcus granulosus tumor protein p63 0.0332 0.0759 0.0758
Trypanosoma brucei metacaspase MCA3 0.0047 0.0075 0.1112
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0064 0.0063
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0148 0.0317 0.1939
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0118 0.0293
Echinococcus multilocularis caspase 3 0.0077 0.0147 0.0146
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.002 0.0011 0.032
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Leishmania major metacaspase, putative 0.0047 0.0075 0.1112
Schistosoma mansoni cpg binding protein 0.003 0.0036 0.0035
Schistosoma mansoni serine/threonine protein kinase 0.0189 0.0416 0.0416
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Leishmania major cysteine peptidase A (CPA) 0.0051 0.0086 0.1279
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0176 0.0175
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0068 0.0413
Echinococcus multilocularis GPCR, family 2 0.0064 0.0116 0.0115
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0013 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0118 0.0118
Schistosoma mansoni ferritin light chain 0.0018 0.0006 0.0005
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0013 0.0012
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0004 0.0009
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.0162 0.5089
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0013 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0011 0.0065
Loa Loa (eye worm) hypothetical protein 0.0104 0.0212 0.0526
Loa Loa (eye worm) cysteine protease 0.0051 0.0086 0.0213
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.0431 0.6427
Echinococcus multilocularis ubiquitin specific protease 41 0.0042 0.0064 0.0063
Entamoeba histolytica p21-activated kinase 0.0455 0.1052 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0012 0.0029
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0011 0.0065
Loa Loa (eye worm) hypothetical protein 0.0049 0.0082 0.0202
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0137 0.0293 0.0728
Schistosoma mansoni chromosome transmission fidelity factor 0.002 0.0011 0.001
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0013 0.0187
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0013 0.0012
Onchocerca volvulus 0.0097 0.0195 0.1189
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0132 0.2408
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.009 0.0549
Echinococcus granulosus tar DNA binding protein 0.0065 0.0118 0.0118
Trichomonas vaginalis set domain proteins, putative 0.0698 0.1636 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.022 0.049 0.8928
Echinococcus granulosus cathepsin l cysteine peptidase 0.0051 0.0086 0.0086
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0062 0.0111 0.1655
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0033 0.0043 0.0043
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0032 0.0041 0.0606
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0033 0.0041 0.0611
Treponema pallidum NADH oxidase 0.0033 0.0043 0.242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0056 0.0342
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0107 0.335
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0084 0.0516
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0043 0.064
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0148 0.0317 0.4725
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0455 0.1052 0.1052
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0019 0.033
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0086 0.0524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0063 0.0384
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0013 0.0031
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.002 0.0011 0.0096
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0029 0.0032 0.1457
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0026 0.0027 0.0391
Plasmodium vivax ataxin-2 like protein, putative 0.0049 0.0082 0.4084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0086 0.0527
Schistosoma mansoni protein kinase 0.0271 0.0612 0.0612
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0086 0.0086
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.016 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0013 0.0031
Echinococcus multilocularis serine protein kinase ATM 0.0033 0.0041 0.0041
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0004 0.0003
Trichomonas vaginalis inositol monophosphatase, putative 0.0015 0.0001 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0086 0.0527
Loa Loa (eye worm) hypothetical protein 0.0071 0.0132 0.0329
Brugia malayi Probable ClpP-like protease 0.0083 0.0162 0.0401
Trypanosoma brucei metacaspase 5, putative 0.0047 0.0075 0.1112
Echinococcus granulosus 3'partial|serine:threonine protein kinase PAK 2 0.0266 0.06 0.0599
Schistosoma mansoni survival motor neuron protein 0.0097 0.0195 0.0194
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.0162 0.5089
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Plasmodium vivax glutathione reductase, putative 0.0096 0.0194 1
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0123 0.0259 0.0258
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0107 0.0106
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0033 0.0041 0.0611
Loa Loa (eye worm) hypothetical protein 0.0053 0.009 0.0222
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.0162 1
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0043 0.064
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0148 0.0317 0.4725
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0025
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0064 0.0116 0.0287
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0107 0.3162
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0007 0.0017
Entamoeba histolytica cysteine protease, putative 0.0026 0.0027 0.0249
Giardia lamblia Replication factor C, subunit 1 0.002 0.0011 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0041 0.0252
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0046 0.0112
Brugia malayi Pre-SET motif family protein 0.0614 0.1433 0.3567
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0051 0.0086 0.4119
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0013 0.0031
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0042 0.0064 0.0943
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0083 0.0162 0.8229
Onchocerca volvulus 0.0698 0.1636 1
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0327 0.0327
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0021 0.0013 0.0229
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0148 0.0317 1
Entamoeba histolytica hypothetical protein 0.0266 0.06 0.5698
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0051 0.0086 0.0213
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0032 0.0041 0.0606
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0031
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0043 0.1212
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0013 0.0374
Schistosoma mansoni serine/threonine protein kinase 0.0189 0.0416 0.0416
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0064 0.0116 0.0115
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0043 0.064
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0107 0.0106

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 6.89 Displacement of [3H]AVP from human V1A receptor expressed in CHO cells ChEMBL. 21458261

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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