Detailed information for compound 1517607

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 503.414 | Formula: C16H15BrN4O4S3
  • H donors: 1 H acceptors: 6 LogP: 2.85 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: Cc1ccc(cc1)S(=O)(=O)N(c1nnc(s1)S(=O)(=O)N)Cc1ccc(cc1)Br
  • InChi: 1S/C16H15BrN4O4S3/c1-11-2-8-14(9-3-11)28(24,25)21(10-12-4-6-13(17)7-5-12)15-19-20-16(26-15)27(18,22)23/h2-9H,10H2,1H3,(H2,18,22,23)
  • InChiKey: CXWBNFDJWLEADI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0124 0.0269 0.0306
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0021 0.0017 0.0534
Leishmania major cytochrome p450-like protein 0.0021 0.0017 0.0014
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0026 0.0882
Brugia malayi hypothetical protein 0.0025 0.0026 0.0026
Trypanosoma brucei cytochrome P450, putative 0.003 0.0038 0.0036
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0018 0.0008 0.0198
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0049 0.0084 0.0084
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0117 0.0252 0.0287
Loa Loa (eye worm) hypothetical protein 0.0031 0.0042 0.0042
Echinococcus granulosus 7TM GPCR rhodopsin 0.0049 0.0084 0.0096
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0049 0.0084 0.0084
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0013 0.0015
Brugia malayi Pre-SET motif family protein 0.0216 0.0493 0.0493
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0013 0.001
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0049 0.0084 0.0095
Giardia lamblia DINP protein human, muc B family 0.002 0.0013 0.1284
Loa Loa (eye worm) hypothetical protein 0.0124 0.0269 0.0269
Schistosoma mansoni acetylcholine receptor subunit beta 0.0022 0.002 0.0023
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0124 0.0269 0.0306
Brugia malayi Serotonin receptor 0.0049 0.0084 0.0084
Onchocerca volvulus 0.0049 0.0084 0.0096
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0144 0.0164
Schistosoma mansoni microtubule-associated protein tau 0.0675 0.1615 0.1836
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0124 0.0269 1
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0021 0.0017 0.0468
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Onchocerca volvulus 0.0117 0.0252 0.0287
Onchocerca volvulus 0.0022 0.002 0.0023
Onchocerca volvulus 0.0031 0.0041 0.0046
Echinococcus granulosus sodium and chloride dependent glycine 0.0124 0.0269 0.0306
Echinococcus granulosus neuropeptide FF receptor 2 0.0049 0.0084 0.0096
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0049 0.0084 0.0095
Brugia malayi Serotonin receptor 0.0049 0.0084 0.0084
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0049 0.0084 0.0095
Loa Loa (eye worm) hypothetical protein 0.0117 0.0252 0.0252
Schistosoma mansoni sodium-dependent amino acid transporter 0.0124 0.0269 0.0306
Mycobacterium tuberculosis Probable dehydrogenase 0.0112 0.0239 0.8854
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0036 0.1134
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Brugia malayi Pre-SET motif family protein 0.0031 0.0041 0.0041
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0124 0.0269 0.0306
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0038 0.0038
Onchocerca volvulus 0.0117 0.0252 0.0287
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Brugia malayi Uncoordinated protein 44 0.0014 0.000000005199 0.000000005199
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0084 0.0096
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0229 0.3974
Onchocerca volvulus 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0049 0.0084 0.0084
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0058 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0124 0.0269 0.0269
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0021 0.0017 0.0534
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0036 0.0053 0.0053
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0085 0.0085
Plasmodium falciparum amino acid transporter, putative 0.0124 0.0269 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Schistosoma mansoni hypothetical protein 0.002 0.0013 0.0015
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0049 0.0084 0.0084
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0058 0.0055
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0049 0.0084 0.0095
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0025 0.0026 0.0023
Schistosoma mansoni survival motor neuron protein 0.0049 0.0085 0.0097
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0026 0.0882
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0013 0.001
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0084 0.0096
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.0013
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0003 0.0004
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0036 0.1262
Brugia malayi neuropeptide F receptor 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.002
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0026 0.0029 0.0033
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0049 0.0084 0.0095
Brugia malayi G-protein coupled receptor 0.0049 0.0084 0.0084
Brugia malayi 6-phosphofructokinase 0.0108 0.0229 0.0229
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0084 0.0096
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0112 0.0239 0.8854
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0049 0.0084 0.0084
Brugia malayi Protein kinase domain containing protein 0.0014 0.000000005199 0.000000005199
Onchocerca volvulus Putative nachr subunit 0.0049 0.0084 0.0095
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0021 0.0017 0.0534
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0058 0.0066
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0049 0.0084 0.0084
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0085 0.0085
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0007 0.0004
Schistosoma mansoni alpha-1 adrenergic receptor 0.0049 0.0084 0.0096
Echinococcus granulosus G protein coupled receptor 139 0.0049 0.0084 0.0096
Trypanosoma brucei C-8 sterol isomerase, putative 0.4104 1 1
Loa Loa (eye worm) glutathione reductase 0.0049 0.0085 0.0085
Onchocerca volvulus Neuropeptide F receptor homolog 0.0049 0.0084 0.0096
Schistosoma mansoni neuropeptide f receptor 76f 0.0049 0.0084 0.0096
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0049 0.0084 0.0084
Brugia malayi hypothetical protein 0.0022 0.002 0.002
Schistosoma mansoni DNA polymerase eta 0.002 0.0013 0.0015
Echinococcus granulosus neuropeptide receptor 0.0049 0.0084 0.0096
Echinococcus multilocularis nAChR subunit 0.0026 0.0029 0.0033
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0049 0.0084 0.0084
Brugia malayi Dopamine receptor protein 1 0.0049 0.0084 0.0084
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0124 0.0269 0.0306
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.0049 0.0084 0.0096
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0051 0.0051
Echinococcus granulosus neuropeptide s receptor 0.0049 0.0084 0.0096
Onchocerca volvulus 0.0124 0.0269 0.0306
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0124 0.0269 0.0269
Brugia malayi Cytochrome P450 family protein 0.003 0.0038 0.0038
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0007 0.0004
Schistosoma mansoni neurotransmitter gated ion channel 0.0022 0.002 0.0023
Echinococcus granulosus sodium and chloride dependent glycine 0.0124 0.0269 0.0306
Schistosoma mansoni amine GPCR 0.0049 0.0084 0.0096
Toxoplasma gondii thioredoxin reductase 0.0049 0.0085 0.3093
Schistosoma mansoni amine GPCR 0.0049 0.0084 0.0096
Onchocerca volvulus 0.0049 0.0084 0.0096
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0084 0.0096
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0049 0.0084 0.0084
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0061 0.007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0084 0.0096
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0124 0.0269 1
Echinococcus granulosus glycine receptor subunit alpha 1 0.0049 0.0084 0.0095
Echinococcus granulosus synaptic vesicular amine transporter 0.0187 0.0422 0.048
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0124 0.0269 1
Schistosoma mansoni hypothetical protein 0.0049 0.0085 0.0097
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0021 0.0017 0.0534
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0013 0.0294
Echinococcus multilocularis serotonin transporter 0.0732 0.1755 0.1995
Loa Loa (eye worm) hypothetical protein 0.0732 0.1755 0.1755
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0049 0.0084 0.0095
Brugia malayi 6-phosphofructokinase 0.0108 0.0229 0.0229
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0049 0.0084 0.0084
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0049 0.0084 0.0084
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.003 0.0038 0.1425
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.002
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0021 0.0017 0.0534
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0124 0.0269 0.0306
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0049 0.0084 0.0095
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0007 0.0008
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0022 0.002 0.002
Brugia malayi hypothetical protein 0.0049 0.0084 0.0084
Brugia malayi hypothetical protein 0.0049 0.0084 0.0084
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0049 0.0084 0.0096
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.0229 0.0226
Brugia malayi hypothetical protein 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Echinococcus granulosus fmrfamide receptor 0.0049 0.0084 0.0096
Onchocerca volvulus 0.0124 0.0269 0.0306
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0026 0.0029 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0084 0.0096
Brugia malayi hypothetical protein 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0034 0.0048 0.0048
Brugia malayi Cytochrome P450 family protein 0.0021 0.0017 0.0017
Echinococcus granulosus tm gpcr rhodopsin 0.1133 0.2736 0.311
Onchocerca volvulus 0.0246 0.0567 0.0644
Onchocerca volvulus 0.0049 0.0084 0.0095
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.0229 0.8402
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0013 0.001
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0049 0.0084 0.0084
Loa Loa (eye worm) ACC-1 protein 0.0049 0.0084 0.0084
Trypanosoma brucei trypanothione reductase 0.0049 0.0085 0.0082
Schistosoma mansoni myosin xvIII 0.0049 0.0084 0.0096
Schistosoma mansoni neuropeptide receptor 0.0049 0.0084 0.0096
Schistosoma mansoni neuropeptide receptor 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.0124 0.0269 0.0269
Schistosoma mansoni loxhd1 0.002 0.0013 0.0015
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0061 0.007
Onchocerca volvulus 0.0049 0.0084 0.0096
Schistosoma mansoni adenoreceptor 0.0049 0.0084 0.0096
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0049 0.0084 0.0096
Schistosoma mansoni hypothetical protein 0.0021 0.0017 0.0019
Toxoplasma gondii cytochrome p450 superfamily protein 0.0021 0.0017 0.0536
Echinococcus multilocularis microtubule associated protein 2 0.0675 0.1615 0.1836
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.0229 1
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.0187 0.0422 0.0422
Schistosoma mansoni opsin-like receptor 0.0049 0.0084 0.0096
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0125 0.0123
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0049 0.0084 0.0096
Echinococcus multilocularis dna polymerase eta 0.002 0.0013 0.0015
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0084 0.0096
Onchocerca volvulus 0.0049 0.0084 0.0096
Echinococcus multilocularis 0.0021 0.0017 0.0019
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0084 0.0096
Brugia malayi hypothetical protein 0.0022 0.002 0.002
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0013 0.0015
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0013 0.001
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0021 0.0017 0.0468
Brugia malayi Dopamine receptor 0.0049 0.0084 0.0084
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0732 0.1755 0.1995
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0022 0.002 0.0023
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0021 0.0017 0.0534
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0036 0.0053 0.0061
Schistosoma mansoni rab6-interacting 0.002 0.0013 0.0015
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0084 0.0084
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0007 0.0004
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0124 0.0269 0.0306
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0007 0.0004
Giardia lamblia Sgs1 DNA helicase, putative 0.0018 0.0008 0.0282
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0036 0.0053 0.0061
Echinococcus multilocularis neuropeptide receptor A26 0.0049 0.0084 0.0096
Schistosoma mansoni DNA helicase recq1 0.0018 0.0008 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0013 0.001
Echinococcus granulosus geminin 0.0349 0.0818 0.093
Brugia malayi RE15519p 0.0049 0.0084 0.0084
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0021 0.0017 0.0468
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Brugia malayi Dopamine receptor protein 2 0.0049 0.0084 0.0084
Echinococcus multilocularis allatostatin A receptor 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.002
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0125 0.0123
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0112 0.0239 0.8854
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.3612 0.8797 0.8797
Onchocerca volvulus 0.0049 0.0084 0.0096
Schistosoma mansoni ap endonuclease 0.0038 0.0058 0.0066
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0007 0.0144
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Brugia malayi hypoxia-induced factor 1 0.0147 0.0324 0.0324
Brugia malayi hypothetical protein 0.0049 0.0084 0.0084
Schistosoma mansoni hypothetical protein 0.0049 0.0084 0.0096
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0047 0.0047
Loa Loa (eye worm) solute carrier family 6 member 4 0.0732 0.1755 0.1755
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0124 0.0269 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.002
Onchocerca volvulus 0.0049 0.0084 0.0096
Echinococcus multilocularis sex peptide receptor 0.0049 0.0084 0.0096
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0003 0.0003
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0013 0.0389
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0084 0.0096
Echinococcus granulosus GPCR family 2 0.0016 0.0003 0.0004
Plasmodium falciparum glutathione reductase 0.0017 0.0007 0.0144
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.0229 0.8487
Schistosoma mansoni sodium/chloride dependent transporter 0.0124 0.0269 0.0306
Schistosoma mansoni amine GPCR 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Plasmodium vivax glutathione reductase, putative 0.0049 0.0085 0.3093
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0017 0.0017
Loa Loa (eye worm) phosphofructokinase 0.0108 0.0229 0.0229
Echinococcus granulosus tachykinin peptides receptor 99D 0.0049 0.0084 0.0096
Schistosoma mansoni acetylcholine receptor-related 0.0022 0.002 0.0023
Plasmodium falciparum thioredoxin reductase 0.0049 0.0085 0.3093
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0036 0.0531
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0022 0.002 0.0023
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0049 0.0084 0.0084
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0058 0.0911
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0021 0.0017 0.0534
Onchocerca volvulus 0.0117 0.0252 0.0287
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0021 0.0017 0.0534
Schistosoma mansoni histamine h1 receptor 0.0049 0.0084 0.0096
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0036 0.1262
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0036 0.0531
Echinococcus multilocularis sodium and chloride dependent glycine 0.0124 0.0269 0.0306
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.0034 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Onchocerca volvulus 0.0022 0.002 0.0023
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0022 0.002 0.002
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0125 0.0125
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0124 0.0269 1
Echinococcus multilocularis geminin 0.0349 0.0818 0.093
Onchocerca volvulus 0.0049 0.0084 0.0096
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0229 0.0229
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0038 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0084 0.0096
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0124 0.0269 0.0306
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0007 0.0144
Schistosoma mansoni opsin-like receptor 0.0049 0.0084 0.0096
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1133 0.2736 0.311
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0026 0.0023
Plasmodium falciparum thioredoxin reductase 0.0017 0.0007 0.0144
Schistosoma mansoni nAChR subunit 0.0049 0.0084 0.0095
Loa Loa (eye worm) RecQ helicase 0.0043 0.0069 0.0069
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0026 0.0882
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0021 0.0017 0.0014
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0085 0.3093
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.002
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0036 0.1262
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0022 0.002 0.0023
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0229 0.0226
Loa Loa (eye worm) hypothetical protein 0.002 0.0013 0.0013
Brugia malayi vesicular acetylcholine transporter unc-17 0.3612 0.8797 0.8797
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0124 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0036 0.1262
Brugia malayi G protein-coupled receptor 0.0049 0.0084 0.0084
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0003 0.0003
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0022 0.002 0.0023
Brugia malayi follicle stimulating hormone receptor 0.0512 0.1217 0.1217
Loa Loa (eye worm) LGC-31 protein 0.0049 0.0084 0.0084
Brugia malayi Cytochrome P450 family protein 0.0021 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.0229 0.1273
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0084 0.0096
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0021 0.0017 0.0534
Echinococcus granulosus neuropeptide receptor 0.0049 0.0084 0.0096
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0084 0.0096
Brugia malayi glutathione reductase 0.0049 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.2097 0.5094 0.5094
Brugia malayi G protein-coupled receptor F59B2.13 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0159 0.0354 0.0354
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0058 0.2057
Brugia malayi ORL1-like opioid receptor 0.0049 0.0084 0.0084
Schistosoma mansoni hypothetical protein 0.0349 0.0818 0.093
Echinococcus multilocularis g-protein coupled receptor 0.0049 0.0084 0.0096
Echinococcus multilocularis glycine receptor subunit beta 0.0049 0.0084 0.0095
Schistosoma mansoni nAChR subunit 0.0022 0.002 0.0023
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0125 0.0125
Echinococcus multilocularis vesicular acetylcholine transporter 0.3612 0.8797 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0049 0.0084 0.0096
Schistosoma mansoni nAChR subunit 0.0049 0.0084 0.0095
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0049 0.0084 0.0096
Echinococcus granulosus orexin receptor type 2 0.0049 0.0084 0.0096
Brugia malayi sulfakinin receptor protein 0.0049 0.0084 0.0084
Echinococcus granulosus microtubule associated protein 2 0.0675 0.1615 0.1836
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0084 0.0096
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0007 0.0004
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0049 0.0084 0.0095
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0058 0.0066
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0084 0.0096
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0049 0.0084 0.0084
Schistosoma mansoni vesicular acetylcholine transporter 0.3612 0.8797 1
Brugia malayi hypothetical protein 0.0049 0.0084 0.0084
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0022 0.002 0.002
Leishmania major DNA polymerase kappa, putative 0.002 0.0013 0.001
Brugia malayi hypothetical protein 0.002 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0035 0.1199
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0013 0.0013
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0732 0.1755 0.1755
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0049 0.0084 0.0095
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0085 0.3086
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0084 0.0096
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0124 0.0269 0.0306
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0038 0.0043
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0124 0.0269 0.0269
Echinococcus multilocularis dna polymerase kappa 0.002 0.0013 0.0015
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0058 0.0055
Echinococcus granulosus dna polymerase kappa 0.002 0.0013 0.0015
Loa Loa (eye worm) melatonin receptor type 1A 0.0049 0.0084 0.0084
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0084 0.0096
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0058 0.0055
Schistosoma mansoni nAChR subunit 0.0049 0.0084 0.0095
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0084 0.0096
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.002
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0229 0.3974
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Echinococcus granulosus neuropeptide receptor A26 0.0049 0.0084 0.0096
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0013 0.0015
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0084 0.0096
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0021 0.0017 0.0534
Leishmania major DNA polymerase eta, putative 0.002 0.0013 0.001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0041 0.0046
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0007 0.0004
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0007 0.0004
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0036 0.1134
Plasmodium vivax SET domain protein, putative 0.0031 0.0041 0.1429
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0049 0.0084 0.0096
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0085 0.0097
Echinococcus multilocularis somatostatin receptor 0.0049 0.0084 0.0096
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0007 0.0004
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0084 0.0084
Brugia malayi phosphofructokinase 0.0108 0.0229 0.0229
Brugia malayi isocitrate dehydrogenase 0.0015 0.0003 0.0003
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0049 0.0084 0.0095
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0022 0.002 0.002
Schistosoma mansoni neuropeptide receptor 0.0049 0.0084 0.0096
Brugia malayi hypothetical protein 0.0016 0.0005 0.0005
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0036 0.0531
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0021 0.0017 0.0468
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0058 0.0066
Schistosoma mansoni nAChR subunit 0.0049 0.0084 0.0095
Onchocerca volvulus 0.0049 0.0084 0.0096
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.4104 1 1
Plasmodium vivax amine transporter, putative 0.0124 0.0269 1
Schistosoma mansoni cytochrome P450 0.0021 0.0017 0.0019
Brugia malayi Thioredoxin reductase 0.0049 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0016 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Loa Loa (eye worm) TYRA-2 protein 0.0049 0.0084 0.0084
Echinococcus granulosus glycine receptor subunit alpha 1 0.0049 0.0084 0.0095
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0084 0.0096
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0022 0.002 0.0023
Trichomonas vaginalis DNA helicase recq1, putative 0.0043 0.0069 0.1119
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0026
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0049 0.0084 0.0095
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0084 0.0096
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0084 0.0096
Onchocerca volvulus 0.0022 0.002 0.0023
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0036 0.583
Echinococcus granulosus alpha 1A adrenergic receptor 0.0049 0.0084 0.0096
Schistosoma mansoni lipoxygenase 0.0117 0.0252 0.0286
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0229 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0036 0.1262
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Toxoplasma gondii hypothetical protein 0.0124 0.0269 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0084 0.0096
Schistosoma mansoni hypothetical protein 0.0016 0.0003 0.0004
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0124 0.0269 0.0306
Echinococcus granulosus RUN 0.002 0.0013 0.0015
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0013 0.001
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0013 0.0381
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0021 0.0017 0.0534
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0125 0.0123
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0041 0.0046
Onchocerca volvulus 0.0049 0.0084 0.0096
Brugia malayi GnHR receptor homolog 0.0049 0.0084 0.0084
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0041 0.0046
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0008 0.0008
Brugia malayi Abnormal catecholamine distribution protein 1 0.0187 0.0422 0.0422
Echinococcus granulosus bloom syndrome protein 0.0043 0.0069 0.0079
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0049 0.0084 0.0095
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0007 0.0008
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0021 0.0017 0.0534
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0036 0.017
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0026 0.0029 0.0029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0021 0.0017 0.0534
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0017 0.0014
Schistosoma mansoni sodium/chloride dependent transporter 0.0732 0.1755 0.1995
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0013 0.0015
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Plasmodium falciparum transporter, putative 0.0124 0.0269 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0084 0.0096
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0229 0.0229
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0013 0.001
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0036 0.0531
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0049 0.0084 0.0095
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0732 0.1755 0.1755
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0041 0.1429
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0026 0.0029 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0013 0.001
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0021 0.0017 0.0468
Brugia malayi hypothetical protein 0.0241 0.0555 0.0555
Onchocerca volvulus 0.0732 0.1755 0.1995
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0049 0.0084 0.0095
Schistosoma mansoni vesicular amine transporter 0.0187 0.0422 0.048
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0013 0.001
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0007 0.0144
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0084 0.0096
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0021 0.0017 0.0468
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0003 0.0003
Echinococcus granulosus somatostatin receptor 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0013 0.001
Brugia malayi hypothetical protein 0.0022 0.002 0.002
Leishmania major trypanothione reductase 0.0049 0.0085 0.0082
Trypanosoma cruzi C-8 sterol isomerase, putative 0.4104 1 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Loa Loa (eye worm) doublecortin family protein 0.002 0.0013 0.0013
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.0124 0.0269 0.0269
Echinococcus granulosus g protein coupled receptor 0.0049 0.0084 0.0096
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0049 0.0084 0.0095
Echinococcus granulosus g protein coupled receptor 0.0049 0.0084 0.0096
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0058 0.0058
Onchocerca volvulus 0.0049 0.0084 0.0095
Loa Loa (eye worm) hypothetical protein 0.0124 0.0269 0.0269
Onchocerca volvulus 0.0049 0.0084 0.0096
Schistosoma mansoni rab6-interacting 0.002 0.0013 0.0015
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0049 0.0084 0.0096
Echinococcus granulosus allatostatin A receptor 0.0049 0.0084 0.0096
Leishmania major protein kinase, putative 0.0017 0.0007 0.0004
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0049 0.0084 0.0095
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0021 0.0017 0.0534
Schistosoma mansoni polycystin 1-related 0.002 0.0013 0.0015
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0007 0.0004
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0124 0.0269 1
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0021 0.0252
Brugia malayi AKH receptor 0.0049 0.0084 0.0084
Brugia malayi Cation transporter family protein 0.0049 0.0084 0.0084
Brugia malayi putative neuropeptide receptor 0.0049 0.0084 0.0084
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0144 0.0164
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.000000005199 0.0000000059102
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Echinococcus multilocularis GPCR, family 2 0.0016 0.0003 0.0004
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0049 0.0084 0.0096
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0049 0.0084 0.0084
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0049 0.0084 0.0095
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0112 0.0239 0.8854
Schistosoma mansoni hypothetical protein 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypoxia-induced factor 1 0.0147 0.0324 0.0324
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0007 0.0004
Echinococcus granulosus single minded 2 0.0038 0.0059 0.0067
Schistosoma mansoni hypothetical protein 0.0016 0.0003 0.0004
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0125 0.0143
Echinococcus multilocularis glycine receptor subunit beta 0.0049 0.0084 0.0095
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0007 0.0004
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0229 0.026
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.0229 0.026
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0036 0.0053 0.0053
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0084 0.0096
Echinococcus multilocularis serotonin receptor 0.0049 0.0084 0.0096
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0013 0.001
Schistosoma mansoni amine GPCR 0.0049 0.0084 0.0096
Echinococcus multilocularis neuropeptide s receptor 0.0049 0.0084 0.0096
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0125 0.5197
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0021 0.0017 0.0534
Brugia malayi excitatory GABA receptor EXP-1A 0.0049 0.0084 0.0084
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0125 0.0143
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Schistosoma mansoni ap endonuclease 0.0038 0.0058 0.0066
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0124 0.0269 1
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0021 0.0017 0.0014
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0058 0.2061
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0021 0.0017 0.0468
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0007 0.0144
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0085 0.0082
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0084 0.0096
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0049 0.0084 0.0084
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0084 0.0096
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0013 0.0015
Onchocerca volvulus 0.0049 0.0084 0.0096
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0007 0.0008
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0021 0.0017 0.0468
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0084 0.0096
Onchocerca volvulus 0.0049 0.0084 0.0096
Plasmodium falciparum glutathione reductase 0.0049 0.0085 0.3093
Leishmania major cytochrome p450-like protein 0.0021 0.0017 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0229 0.3974
Echinococcus granulosus survival motor neuron protein 1 0.0241 0.0555 0.0631
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0008
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0058 0.2293
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0084 0.0096
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0013 0.0015
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0008 0.0198
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0036 0.0531
Loa Loa (eye worm) hypothetical protein 0.0241 0.0555 0.0555
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0036 0.1074
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0022 0.002 0.002
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0018 0.0008 0.0008
Schistosoma mansoni neuropeptide receptor 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.002
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0124 0.0269 0.0269
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0049 0.0084 0.0095
Loa Loa (eye worm) cytochrome P450 0.0021 0.0017 0.0017
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0013 0.001
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0124 0.0269 0.0269
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0049 0.0084 0.0096
Onchocerca volvulus 0.0049 0.0084 0.0095
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Treponema pallidum sodium- and chloride- dependent transporter 0.0732 0.1755 1
Echinococcus granulosus serotonin transporter 0.0732 0.1755 0.1995
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0229 0.026
Schistosoma mansoni biogenic amine receptor 0.0049 0.0084 0.0096
Brugia malayi hypothetical protein 0.0049 0.0084 0.0084
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0013 0.0117
Echinococcus granulosus glycine receptor subunit beta 0.0049 0.0084 0.0095
Brugia malayi hypothetical protein 0.0022 0.002 0.002
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0013 0.001
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0003 0.0004
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0084 0.0096
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0003 0.0003
Schistosoma mansoni neurotransmitter gated ion channel 0.0026 0.0029 0.0033
Echinococcus multilocularis neuropeptide receptor 0.0049 0.0084 0.0096
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0084 0.0096
Leishmania major cytochrome p450-like protein 0.003 0.0038 0.0036
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0022 0.002 0.002
Echinococcus multilocularis nAChR subunit 0.0049 0.0084 0.0095
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0124 0.0269 0.0306
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0084 0.0096
Brugia malayi cytochrome P450 0.0021 0.0017 0.0017
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0026 0.0882
Loa Loa (eye worm) hypothetical protein 0.0049 0.0085 0.0085
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0058 0.2059
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0124 0.0269 0.0306
Schistosoma mansoni hypothetical protein 0.0349 0.0818 0.093
Echinococcus multilocularis serotonin receptor 0.0049 0.0084 0.0096
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0049 0.0084 0.0096
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.0252 0.0286
Echinococcus multilocularis G-protein coupled receptor, putative 0.0049 0.0084 0.0096
Brugia malayi hypothetical protein 0.0049 0.0084 0.0084
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0084 0.0096
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Echinococcus multilocularis dro:myosuppressin receptor 0.0049 0.0084 0.0096
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.000000005199 0.0000000059102
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0036 0.0531
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.3612 0.8797 1
Echinococcus granulosus nAChR subunit 0.0026 0.0029 0.0033
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0085 0.0085
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0049 0.0084 0.0084
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0013 0.001
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0007 0.0004
Echinococcus granulosus g-protein coupled receptor 0.0049 0.0084 0.0096
Onchocerca volvulus 0.0049 0.0084 0.0096
Brugia malayi Death domain containing protein 0.0014 0.000000005199 0.000000005199
Echinococcus granulosus g protein coupled receptor 0.0049 0.0084 0.0096
Echinococcus granulosus glycine receptor subunit beta 0.0049 0.0084 0.0095
Echinococcus multilocularis sodium and chloride dependent glycine 0.0124 0.0269 0.0306
Schistosoma mansoni nAChR subunit 0.0049 0.0084 0.0095
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0049 0.0084 0.0096
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0084 0.0096
Schistosoma mansoni aryl hydrocarbon receptor 0.0047 0.0081 0.0092
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0084 0.0096
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0021 0.0018
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0013 0.001
Onchocerca volvulus 0.0049 0.0084 0.0096
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0229 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0013 0.0015
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0049 0.0084 0.0084
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0003 0.0003
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0084 0.0084
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0047 0.0729
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0021 0.0017 0.0534
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0013 0.0015
Onchocerca volvulus 0.0049 0.0085 0.0097
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0007 0.0004
Brugia malayi hypothetical protein 0.0022 0.002 0.002
Echinococcus granulosus serotonin receptor 0.0049 0.0084 0.0096
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0021 0.0017 0.0534
Brugia malayi hypothetical protein 0.0159 0.0354 0.0354
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.000000005199 0.0000000059102
Schistosoma mansoni lipoxygenase 0.0082 0.0165 0.0188
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0021 0.0017 0.0468
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0041 0.0046
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0018 0.0008 0.0009
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0049 0.0084 0.0084
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0084 0.0096
Echinococcus multilocularis G protein coupled receptor 139 0.0049 0.0084 0.0096
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0049 0.0084 0.0096
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Onchocerca volvulus 0.0049 0.0084 0.0096
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0117 0.0252 0.0287
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0084 0.0096
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0084 0.0096
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0021 0.0018
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.0252 0.0286
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0013 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0084 0.0096
Brugia malayi PAS domain containing protein 0.0047 0.0081 0.0081
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0013 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0084 0.0096
Echinococcus multilocularis orexin receptor type 2 0.0049 0.0084 0.0096
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0049 0.0084 0.0096
Echinococcus granulosus dro:myosuppressin receptor 0.0049 0.0084 0.0096
Schistosoma mansoni single-minded 0.0047 0.0081 0.0092
Loa Loa (eye worm) hypothetical protein 0.0117 0.0252 0.0252
Brugia malayi hypothetical protein 0.002 0.0013 0.0013
Schistosoma mansoni blooms syndrome DNA helicase 0.0034 0.0047 0.0054
Onchocerca volvulus 0.0049 0.0084 0.0096
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0084 0.0096
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0084 0.0096
Schistosoma mansoni biogenic amine receptor 0.0049 0.0084 0.0096
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0049 0.0084 0.0084
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0007 0.0144
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0003 0.0004
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0125 0.0123
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0038 0.0036
Onchocerca volvulus 0.002 0.0013 0.0015
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0229 0.3974
Brugia malayi Tachykinin-like peptides receptor 99D 0.0049 0.0084 0.0084
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0026 0.0029 0.0029
Echinococcus multilocularis neuropeptide FF receptor 2 0.0049 0.0084 0.0096
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0084 0.0084
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0084 0.0096
Echinococcus multilocularis synaptic vesicular amine transporter 0.0187 0.0422 0.048
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.002
Schistosoma mansoni nAChR subunit 0.0049 0.0084 0.0095
Loa Loa (eye worm) GABA receptor subunit 0.0026 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Echinococcus multilocularis survival motor neuron protein 1 0.0241 0.0555 0.0631
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0007 0.0004
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0013 0.001
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0084 0.0096
Schistosoma mansoni opsin-like receptor 0.0049 0.0084 0.0096
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0058 0.0292
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0049 0.0084 0.0095
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0034 0.0047 0.0054
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0021 0.0017 0.0468
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0112 0.0239 0.8854
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0049 0.0084 0.0096
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0036 0.1262
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0013 0.0013
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0021 0.0017 0.0468
Leishmania major C-8 sterol isomerase-like protein 0.4104 1 1
Schistosoma mansoni amine GPCR 0.0049 0.0084 0.0096
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0124 0.0269 0.0306
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0021 0.0018
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0013 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0021 0.0017 0.0534
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0026 0.0029 0.0029
Schistosoma mansoni biogenic amine receptor 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.0865 0.208 0.208
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0084 0.0096
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0049 0.0084 0.0084
Brugia malayi hypothetical protein 0.0124 0.0269 0.0269
Brugia malayi Doublecortin family protein 0.002 0.0013 0.0013
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0124 0.0269 0.0306
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0229 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0058 0.2061
Loa Loa (eye worm) hypothetical protein 0.0095 0.0198 0.0198
Onchocerca volvulus 0.0035 0.0051 0.0058
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0021 0.0017 0.0468
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0021 0.0017 0.0468
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0049 0.0084 0.0084
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0013 0.0381
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0125 0.0143
Loa Loa (eye worm) serotonin transporter b 0.0732 0.1755 0.1755
Schistosoma mansoni sodium/chloride dependent transporter 0.0124 0.0269 0.0306
Trichomonas vaginalis DNA helicase recq, putative 0.0043 0.0069 0.1119
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0021 0.0017 0.0468
Mycobacterium tuberculosis Probable oxidoreductase 0.0124 0.0269 1
Plasmodium vivax hypothetical protein, conserved 0.0124 0.0269 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0049 0.0084 0.0084
Mycobacterium tuberculosis Probable reductase 0.0112 0.0239 0.8854
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0017 0.0014
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0049 0.0084 0.0095
Brugia malayi hypothetical protein 0.0049 0.0084 0.0084
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0036 0.0531
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0084 0.0096
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0058 0.0055
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0013 0.001
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0022 0.002 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0013 0.001
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0124 0.0269 0.0306
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.002
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Echinococcus granulosus hypothetical protein 0.0049 0.0084 0.0096
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0007 0.0144
Loa Loa (eye worm) ACC-1 protein 0.0049 0.0084 0.0084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0084 0.0096
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0124 0.0269 0.0269
Toxoplasma gondii exonuclease III APE 0.0038 0.0058 0.2061
Loa Loa (eye worm) acetylcholine receptor protein 0.0022 0.002 0.002
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0049 0.0084 0.0095
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0041 0.0046
Echinococcus granulosus peptide allatostatin:somatostatin 0.0049 0.0084 0.0096
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0021 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.0022 0.002 0.002
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0037 0.0057 0.2023
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0051 0.1985
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Onchocerca volvulus 0.0026 0.0029 0.0033
Schistosoma mansoni hypothetical protein 0.0016 0.0003 0.0004
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.0229 0.026
Echinococcus granulosus 7tm_1 domain containing protein 0.0049 0.0084 0.0096
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0124 0.0269 0.0269
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0021 0.0017 0.0468
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0732 0.1755 0.1755
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0084 0.0096
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0058 1
Loa Loa (eye worm) norepinephrine transporter 0.0732 0.1755 0.1755
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0036 0.1262
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0049 0.0084 0.0096
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0008 0.0198
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0084 0.0096
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0007 0.0144
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0085 0.0097
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0058 0.0066
Echinococcus granulosus glycine receptor subunit alpha 1 0.0049 0.0084 0.0095
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0049 0.0084 0.0096
Brugia malayi Melatonin receptor type 1A 0.0049 0.0084 0.0084
Toxoplasma gondii hypothetical protein 0.0124 0.0269 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0013 0.0389
Trichomonas vaginalis set domain proteins, putative 0.0246 0.0566 1
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0021 0.0017 0.0534
Schistosoma mansoni growth hormone secretagogue receptor 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.0124 0.0269 0.0269
Echinococcus granulosus vesicular acetylcholine transporter 0.3612 0.8797 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0049 0.0084 0.0096
Brugia malayi larval opioid receptor 0.0049 0.0084 0.0084
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0047 0.0729
Echinococcus multilocularis neuropeptide receptor 0.0049 0.0084 0.0096
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.0493 0.0493
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0013 0.0294
Brugia malayi Cytochrome P450 family protein 0.003 0.0038 0.0038
Echinococcus granulosus sex peptide receptor 0.0049 0.0084 0.0096
Schistosoma mansoni neurotransmitter gated ion channel 0.0022 0.002 0.0023
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0003 0.0003
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0124 0.0269 0.0306
Brugia malayi G-protein coupled receptor 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0022 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0865 0.208 0.208
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0018 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Brugia malayi Bloom's syndrome protein homolog 0.0043 0.0069 0.0069
Brugia malayi neuropeptide F receptor 0.0049 0.0084 0.0084
Brugia malayi Cation transporter family protein 0.0117 0.0252 0.0252
Brugia malayi hypothetical protein 0.0049 0.0084 0.0084
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0229 0.0226
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0007 0.0004
Echinococcus multilocularis bloom syndrome protein 0.0043 0.0069 0.0079
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0013 0.0117
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0007 0.0004
Schistosoma mansoni nAChR subunit 0.0049 0.0084 0.0095
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0049 0.0084 0.0095
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0058 0.0058
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0026 0.0023
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0512 0.1217 0.1217
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0029 0.0036 0.123
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0049 0.0084 0.0084
Schistosoma mansoni DNA helicase recq5 0.0018 0.0008 0.0009
Brugia malayi putative neuropeptide receptor NPR1 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0051 0.0058
Echinococcus granulosus cytochrome P450 2K1 0.0021 0.0017 0.0019
Echinococcus granulosus dna polymerase eta 0.002 0.0013 0.0015
Loa Loa (eye worm) CYP4Cod1 0.003 0.0038 0.0038
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0021 0.0017 0.0468
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0021 0.0017 0.0468
Onchocerca volvulus 0.0026 0.0029 0.0033
Brugia malayi Cation transporter family protein 0.0049 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Entamoeba histolytica recQ family helicase, putative 0.0023 0.0021 0.0349
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0021 0.0017 0.0468
Onchocerca volvulus 0.002 0.0013 0.0015
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0018 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0021 0.0017 0.0468
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0084 0.0096
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0084 0.0096
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0018 0.0008 0.0009
Trypanosoma brucei unspecified product 0.002 0.0013 0.001
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0049 0.0084 0.0084
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0026 0.0029 0.0733
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0112 0.0239 0.8789
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0058 0.0911
Schistosoma mansoni nAChR subunit 0.0022 0.002 0.0023
Echinococcus granulosus nAChR subunit 0.0049 0.0084 0.0095
Onchocerca volvulus 0.0124 0.0269 0.0306
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0084 0.0096
Loa Loa (eye worm) hypothetical protein 0.0049 0.0084 0.0084
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0038 0.0038
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0041 0.0046
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0049 0.0084 0.0096
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0021 0.0017 0.0468
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0049 0.0084 0.0084
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0041 0.0046
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0021 0.0017 0.0534
Echinococcus multilocularis RUN 0.002 0.0013 0.0015
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0085 0.0085

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 5.75 % Activity at human carbonic anhydrase 2 assessed as hydrolysis of p- nitrophenyl acetate at 0.3 umol/L at pH 7.6 ChEMBL. 21524585

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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