Detailed information for compound 1527180

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 388.722 | Formula: C17H12ClF3O5
  • H donors: 2 H acceptors: 4 LogP: 4.52 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C(C(=O)O)Cc1ccc(cc1)Oc1ccc(cc1Cl)C(F)(F)F
  • InChi: 1S/C17H12ClF3O5/c18-13-8-10(17(19,20)21)3-6-14(13)26-11-4-1-9(2-5-11)7-12(15(22)23)16(24)25/h1-6,8,12H,7H2,(H,22,23)(H,24,25)
  • InChiKey: WFCBSAGHROLWRJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens free fatty acid receptor 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0633 0.1398
Leishmania major carbonic anhydrase-like protein 0.0175 0.3934 1
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0097 0.0027
Brugia malayi PAS domain containing protein 0.0047 0.0924 0.1443
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Onchocerca volvulus 0.0031 0.054 0.1272
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0633 0.0678
Mycobacterium ulcerans integral membrane transport protein 0.0014 0.0144 0.0227
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0026 0.0418 0.0444
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.3698 0.5765
Mycobacterium ulcerans epoxide hydrolase EphA 0.0162 0.3622 0.5699
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.3698 0.5765
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0014 0.0132 0.0207
Schistosoma mansoni hypothetical protein 0.0398 0.92 1
Echinococcus multilocularis geminin 0.0337 0.7757 0.843
Trichomonas vaginalis sugar transport protein, putative 0.0014 0.0144 0.0102
Loa Loa (eye worm) hypothetical protein 0.0031 0.0527 0.0752
Loa Loa (eye worm) hypothetical protein 0.0014 0.0136 0.0183
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0813 0.1169
Echinococcus granulosus Chromobox protein 3 0.0012 0.008 0.0075
Schistosoma mansoni chromobox protein 0.0012 0.008 0.0015
Schistosoma mansoni sugar transporter 0.0014 0.0144 0.0085
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0026 0.0418 0.0444
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2115 0.3244
Onchocerca volvulus 0.0014 0.0144 0.0178
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0141 0.3135 0.336
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0015 0.015 0.0139
Schistosoma mansoni hypothetical protein 0.0015 0.0169 0.0112
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0014 0.0132 0.0259
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0169 0.0172
Schistosoma mansoni sugar transporter 0.0014 0.0144 0.0085
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.1476 0.2134
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0031 0.0549 0.0586
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0114
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0276 0.0313
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0385 0.0469
Schistosoma mansoni neurotransmitter gated ion channel 0.0012 0.0089 0.0025
Schistosoma mansoni aryl hydrocarbon receptor 0.0047 0.0924 0.0939
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.2207 0.3389
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0633 0.1245
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0144 0.0123
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0342 0.0265
Schistosoma mansoni carbonic anhydrase-related 0.0082 0.1745 0.1838
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0026 0.0418 0.0647
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0342 0.0302
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0269 0.0448
Loa Loa (eye worm) sugar transporter 0.0014 0.0144 0.0194
Schistosoma mansoni tar DNA-binding protein 0.0064 0.1324 0.1377
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0269 0.0929
Onchocerca volvulus 0.0026 0.0418 0.0936
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0102 0.2207 0.239
Onchocerca volvulus 0.0014 0.0144 0.0178
Loa Loa (eye worm) GABA receptor subunit 0.0014 0.0136 0.0183
Loa Loa (eye worm) hypothetical protein 0.0014 0.0136 0.0183
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0633 0.0558
Schistosoma mansoni tar DNA-binding protein 0.0064 0.1324 0.1377
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0342 0.0569
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0014 0.0132 0.0259
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0742 0.1056
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0342 0.1006
Schistosoma mansoni hypothetical protein 0.0102 0.2207 0.2343
Onchocerca volvulus 0.0015 0.0159 0.0218
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Trypanosoma cruzi sugar transporter, putative 0.0014 0.0144 0.0123
Leishmania major hypothetical protein, conserved 0.0035 0.0633 0.1398
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0014 0.0132 0.0207
Schistosoma mansoni hypothetical protein 0.0015 0.0169 0.0112
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0344 0.042
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0014 0.0132 0.0207
Loa Loa (eye worm) hypothetical protein 0.0012 0.008 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0549 0.0528
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0014 0.0132 0.0259
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0015 0.0159 0.0161
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0344 0.042
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0549 0.0586
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0165 0.3692 0.3641
Schistosoma mansoni hypothetical protein 0.0337 0.7757 0.8421
Treponema pallidum sodium- and chloride- dependent transporter 0.0015 0.0159 1
Echinococcus multilocularis carbonic anhydrase 0.0082 0.1745 0.1888
Echinococcus granulosus tar DNA binding protein 0.0064 0.1324 0.1429
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.3698 0.5765
Trichomonas vaginalis CAMK family protein kinase 0.0031 0.0549 0.0747
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Plasmodium vivax amine transporter, putative 0.0015 0.0159 0.008
Echinococcus granulosus dna polymerase eta 0.002 0.0269 0.0281
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0551 0.1183
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0551 0.0751
Brugia malayi Cytochrome P450 family protein 0.0014 0.0132 0.0195
Loa Loa (eye worm) hypothetical protein 0.0031 0.0549 0.0784
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0097 0.0027
Toxoplasma gondii ABC1 family protein 0.0035 0.0633 0.085
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0015 0.015 0.0139
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.1035 0.1493
Mycobacterium tuberculosis Conserved protein 0.0035 0.0633 0.1245
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0014 0.0132 0.0091
Loa Loa (eye worm) hypothetical protein 0.0035 0.0633 0.0907
Trichomonas vaginalis chromobox protein, putative 0.0071 0.1476 0.2224
Onchocerca volvulus 0.0026 0.0418 0.0936
Brugia malayi Cam kinase protein 1 0.0031 0.0549 0.0852
Loa Loa (eye worm) carbonic anhydrase 3 0.0175 0.3934 0.5715
Brugia malayi Protein cec-1. 0.0012 0.008 0.0113
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0114
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.008 0.0015
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0031 0.0549 0.1112
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0099 0.2132 0.2308
Echinococcus multilocularis Chromobox protein 3 0.0012 0.008 0.0075
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.0262 0.0514
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.5737 0.9015
Schistosoma mansoni glucose transport protein 0.0102 0.2207 0.2343
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0549 0.0586
Onchocerca volvulus 0.0014 0.0144 0.0178
Brugia malayi cytochrome P450 0.0014 0.0132 0.0195
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0159 0.0237
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0144 0.0099
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0269 0.0528
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.2115 0.5261
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0469 0.0902
Brugia malayi serine/threonine-protein kinase plk-2 0.0098 0.2115 0.332
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0014 0.0144 0.0227
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0015 0.0159 0.0237
Trypanosoma brucei glucose transporter, putative 0.0032 0.0551 0.1117
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0175 0.3934 0.6185
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0132 0.0176
Brugia malayi acetyltransferase, GNAT family protein 0.0141 0.3135 0.4927
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0229 0.0238
Echinococcus multilocularis carbonic anhydrase 0.0082 0.1745 0.1888
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0026 0.0418 0.0386
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0549 0.0586
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0082 0.1745 0.2737
Onchocerca volvulus 0.0014 0.0144 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0144 0.0102
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0132 0.0091
Onchocerca volvulus 0.0012 0.0089 0.0025
Loa Loa (eye worm) hypothetical protein 0.0082 0.1745 0.2527
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0342 0.0361
Echinococcus granulosus glycine receptor subunit beta 0.0026 0.0418 0.0444
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0551 0.1183
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0175 0.3934 0.5715
Schistosoma mansoni nAChR subunit 0.0012 0.0089 0.0025
Brugia malayi hypothetical protein 0.0016 0.018 0.0271
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0014 0.0132 0.0259
Onchocerca volvulus 0.0035 0.0633 0.153
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0951 0.1486
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.3907 0.6099
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0633 0.0907
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0549 0.0586
Plasmodium falciparum hexose transporter 0.0102 0.2207 0.2144
Plasmodium falciparum carbonic anhydrase 0.0082 0.1745 0.1679
Trypanosoma cruzi glucose transporter, putative 0.0014 0.0144 0.0123
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.2207 0.239
Loa Loa (eye worm) hypothetical protein 0.0035 0.0633 0.0907
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0633 0.0997
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0549 0.0586
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.1201 0.1721
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.1201 0.1242
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0014 0.0136 0.0077
Schistosoma mansoni nAChR subunit 0.0026 0.0418 0.0386
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Plasmodium falciparum mitogen-activated protein kinase 2 0.0165 0.3692 0.3641
Loa Loa (eye worm) helicase 0.0012 0.008 0.0101
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0252 0.5737 0.8342
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.015 0.0139
Echinococcus multilocularis cpg binding protein 0.003 0.0504 0.0537
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0114
Brugia malayi hypothetical protein 0.0012 0.0089 0.0127
Trypanosoma cruzi cytochrome P450, putative 0.0014 0.0132 0.0091
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0342 0.0265
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0633 0.0678
Loa Loa (eye worm) hypothetical protein 0.0012 0.008 0.0101
Leishmania major protein kinase, putative 0.0015 0.015 0.0139
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0012 0.0097 0.128
Loa Loa (eye worm) hypothetical protein 0.0014 0.0136 0.0183
Loa Loa (eye worm) hypothetical protein 0.0014 0.0144 0.0194
Echinococcus multilocularis glycine receptor subunit beta 0.0026 0.0418 0.0444
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0162 0.3622 0.7117
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.1124 0.1758
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0633 0.1245
Loa Loa (eye worm) hypothetical protein 0.0014 0.0144 0.0194
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Loa Loa (eye worm) hypothetical protein 0.0014 0.0136 0.0183
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.3698 0.5765
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0633 0.0985
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0169 0.0172
Mycobacterium ulcerans lipase LipD 0.0035 0.0633 0.0997
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.1124 0.1212
Schistosoma mansoni nAChR subunit 0.0026 0.0418 0.0386
Leishmania major GTP-binding protein, putative 0.0021 0.0294 0.0513
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0269 0.0377
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0269 0.0448
Loa Loa (eye worm) norepinephrine transporter 0.0015 0.0159 0.0216
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0466 0.0663
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0114
Echinococcus multilocularis serotonin transporter 0.0015 0.0159 0.0161
Loa Loa (eye worm) hypothetical protein 0.0012 0.008 0.0101
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0014 0.0132 0.0259
Echinococcus granulosus solute carrier family 22 0.0014 0.0144 0.0145
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0646 0.1431
Schistosoma mansoni acetylcholine receptor-related 0.0012 0.0089 0.0025
Onchocerca volvulus 0.0014 0.0136 0.0156
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0633 0.0997
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0014 0.0132 0.0207
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0026 0.0418 0.0594
Trypanosoma brucei glucose transporter 2A 0.0032 0.0551 0.1117
Onchocerca volvulus 0.0015 0.0159 0.0218
Brugia malayi hypothetical protein 0.0014 0.0144 0.0214
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0159 0.0101
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0527 0.1941
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0136 0.0202
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0342 0.0539
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0132 0.0091
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0159 0.0161
Trichomonas vaginalis myo-inositol transporter, putative 0.0014 0.0144 0.0102
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2115 0.3244
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Trypanosoma brucei glucose transporter 1E 0.0032 0.0551 0.1117
Schistosoma mansoni sugar transporter 0.0014 0.0144 0.0085
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0294 0.0216
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0056 0.1124 0.2677
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0902 0.0916
Loa Loa (eye worm) hypothetical protein 0.0025 0.0392 0.0555
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Leishmania major importin beta-1 subunit, putative 0.0023 0.0344 0.0643
Echinococcus multilocularis glycine receptor subunit beta 0.0026 0.0418 0.0444
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0014 0.0132 0.0259
Trypanosoma brucei glucose transporter, putative 0.0032 0.0551 0.1117
Schistosoma mansoni glucose transport protein 0.0102 0.2207 0.2343
Trichomonas vaginalis glutaminase, putative 0.0278 0.6355 1
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0144 0.0145
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0026 0.0418 0.0386
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.0144 0.0065
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.1201 0.1242
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0144 0.0145
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0262 0.4129
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0012 0.0097 0.0094
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.1201 0.189
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0633 0.0997
Echinococcus multilocularis tar DNA binding protein 0.0064 0.1324 0.1429
Schistosoma mansoni protein kinase 0.0031 0.0549 0.0528
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.3042 0.3299
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0633 0.0882
Mycobacterium ulcerans hypothetical protein 0.0035 0.0633 0.0997
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0098 0.2115 0.5261
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0902 0.0916
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0294 0.076
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0704 0.284
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0342 0.0302
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0159 0.0101
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0269 0.0448
Schistosoma mansoni kinase 0.0051 0.1002 0.1025
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0014 0.0132 0.0259
Leishmania major cytochrome p450-like protein 0.0014 0.0132 0.0091
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.5737 0.9015
Giardia lamblia DINP protein human, muc B family 0.002 0.0269 0.0633
Schistosoma mansoni tar DNA-binding protein 0.0064 0.1324 0.1377
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0527 0.2195
Entamoeba histolytica hypothetical protein 0.0023 0.0342 0.129
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0633 0.1245
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Echinococcus granulosus nAChR subunit 0.0014 0.0136 0.0137
Leishmania major protein kinase, putative 0.0015 0.015 0.0139
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.2207 0.239
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0175 0.3934 0.4234
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0097 0.0027
Toxoplasma gondii cytochrome p450 superfamily protein 0.0014 0.0132 0.008
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0646 0.1367
Schistosoma mansoni importin beta-1 0.0028 0.0469 0.0441
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0114
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.5737 0.9015
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0014 0.0132 0.0207
Brugia malayi SET domain containing protein 0.0012 0.0094 0.0136
Echinococcus granulosus chromobox protein 1 0.0071 0.1476 0.1594
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0144 0.0194
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0082 0.1745 0.2737
Loa Loa (eye worm) hypothetical protein 0.0014 0.0144 0.0194
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0269 0.0411
Schistosoma mansoni hypothetical protein 0.0015 0.0169 0.0112
Brugia malayi TAR-binding protein 0.0064 0.1324 0.2073
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0169 0.0253
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0026 0.0418 0.0386
Echinococcus granulosus serotonin transporter 0.0015 0.0159 0.0161
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0014 0.0144 0.0049
Leishmania major hypothetical protein, conserved 0.0025 0.0385 0.0752
Trypanosoma brucei unspecified product 0.002 0.0269 0.0377
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0169 0.023
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0056 0.1124 0.2209
Brugia malayi beta-lactamase family protein 0.0035 0.0633 0.0985
Onchocerca volvulus 0.0014 0.0144 0.0178
Echinococcus granulosus solute carrier family 22 0.0014 0.0144 0.0145
Plasmodium vivax calcium-dependent protein kinase, putative 0.0031 0.0549 0.0473
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0014 0.0132 0.0259
Loa Loa (eye worm) hypothetical protein 0.0015 0.0159 0.0216
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0159 0.0237
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0014 0.0132 0.0207
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0344 0.0643
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0031 0.0549 0.0784
Schistosoma mansoni ran 0.0021 0.0294 0.0249
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Onchocerca volvulus 0.0014 0.0144 0.0178
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0144 0.0194
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0014 0.0132 0.0259
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0089 0.0127
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0144 0.0214
Echinococcus multilocularis dnaJ subfamily B 0.0398 0.92 1
Schistosoma mansoni single-minded 0.0047 0.0924 0.0939
Brugia malayi Valyl-tRNA synthetase 0.0012 0.008 0.0113
Echinococcus multilocularis solute carrier family 22 0.0014 0.0144 0.0145
Mycobacterium tuberculosis Conserved protein 0.0035 0.0633 0.1245
Onchocerca volvulus 0.0026 0.0418 0.0936
Trichomonas vaginalis ran, putative 0.0021 0.0294 0.0341
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0269 0.0377
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0175 0.3934 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0026 0.0418 0.0647
Loa Loa (eye worm) CYP4Cod1 0.0014 0.0132 0.0176
Plasmodium falciparum transporter, putative 0.0015 0.0159 0.008
Schistosoma mansoni nAChR subunit 0.0026 0.0418 0.0386
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0026 0.0418 0.0444
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0097 0.0027
Loa Loa (eye worm) hypothetical protein 0.0015 0.0159 0.0216
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0646 0.0869
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0015 0.0159 0.3474
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0527 0.0562
Loa Loa (eye worm) RNA binding protein 0.0064 0.1324 0.1913
Leishmania major myo-inositol/proton symporter (MIT) 0.0014 0.0144 0.0123
Onchocerca volvulus 0.0012 0.0089 0.0025
Schistosoma mansoni glutaminase 0.0278 0.6355 0.6886
Brugia malayi beta-lactamase 0.0035 0.0633 0.0985
Echinococcus granulosus carbonic anhydrase II 0.0175 0.3934 0.4269
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2207 0.239
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0527 0.0712
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0269 0.0528
Onchocerca volvulus 0.0015 0.0159 0.0218
Loa Loa (eye worm) hypothetical protein 0.0033 0.0589 0.0843
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0269 0.0377
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0014 0.0144 0.5
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0026 0.0418 0.0647
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0014 0.0132 0.0207
Loa Loa (eye worm) hypothetical protein 0.0015 0.0159 0.0216
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0099 0.2132 0.2308
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Brugia malayi hypothetical protein 0.0014 0.0144 0.0214
Schistosoma mansoni ran 0.0021 0.0294 0.0249
Toxoplasma gondii sugar transporter ST2 0.0014 0.0144 0.0099
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0742 0.1831
Onchocerca volvulus 0.0014 0.0144 0.0178
Echinococcus multilocularis carbonic anhydrase 0.0082 0.1745 0.1888
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.0117 0.0116
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0551 0.1117
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0342 0.0418
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0175 0.3934 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0385 0.0546
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.008 0.0015
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0527 0.0562
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.0117 0.0116
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0082 0.1745 0.2737
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0144 0.0214
Trypanosoma cruzi cytochrome P450, putative 0.0014 0.0132 0.0091
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0496 0.0528
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0026 0.0418 0.0444
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0015 0.0159 0.0161
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0026 0.0418 0.0647
Trypanosoma brucei sugar transporter, putative 0.0014 0.0144 0.0049
Leishmania major DNA polymerase kappa, putative 0.002 0.0269 0.0448
Loa Loa (eye worm) hypothetical protein 0.0012 0.008 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0269 0.0377
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0026 0.0418 0.0444
Loa Loa (eye worm) hypothetical protein 0.0014 0.0144 0.0194
Onchocerca volvulus 0.0014 0.0144 0.0178
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0098 0.2115 0.229
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0144 0.0102
Schistosoma mansoni hypothetical protein 0.03 0.6876 0.7455
Brugia malayi Importin beta-1 subunit 0.0028 0.0469 0.0726
Echinococcus multilocularis chromobox protein 2 0.0012 0.008 0.0075
Loa Loa (eye worm) hypothetical protein 0.0014 0.0144 0.0194
Onchocerca volvulus 0.0035 0.0633 0.153
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0785 0.1083
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0149 0.011
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0014 0.0132 0.0207
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0012 0.0089 0.0114
Echinococcus granulosus aryl hydrocarbon receptor 0.0012 0.0097 0.0094
Schistosoma mansoni nAChR subunit 0.0026 0.0418 0.0386
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0011 0.0061 0.0096
Toxoplasma gondii hypothetical protein 0.0015 0.0159 0.0121
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0.008 0.0113
Brugia malayi hypothetical protein 0.0159 0.3554 0.5587
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0026 0.0418 0.0647
Loa Loa (eye worm) hypothetical protein 0.0014 0.0136 0.0183
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0633 0.1245
Loa Loa (eye worm) hypothetical protein 0.0015 0.0169 0.023
Brugia malayi hypothetical protein 0.0012 0.0089 0.0127
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0385 0.0683
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0646 0.1431
Brugia malayi Sugar transporter family protein 0.0014 0.0144 0.0214
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0785 0.1124
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.5089 1
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0014 0.0132 0.0207
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0527 0.0504
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0294 0.0513
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0551 0.1117
Trypanosoma brucei glucose transporter, putative 0.0032 0.0551 0.1117
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.1205 0.1247
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0014 0.0132 0.0259
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.0144 0.0145
Loa Loa (eye worm) hypothetical protein 0.0028 0.0469 0.0667
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0026 0.0418 0.0444
Loa Loa (eye worm) hypothetical protein 0.0035 0.0633 0.0907
Echinococcus multilocularis dna polymerase eta 0.002 0.0269 0.0281
Loa Loa (eye worm) hypothetical protein 0.0159 0.3554 0.5162
Plasmodium vivax hexose transporter 0.0102 0.2207 0.2144
Brugia malayi hypothetical protein 0.0014 0.0144 0.0214
Toxoplasma gondii sugar transporter ST3 0.0014 0.0144 0.0099
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0159 0.0101
Entamoeba histolytica serine/threonine protein kinase, putative 0.0098 0.2115 1
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0646 0.1431
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0014 0.0132 0.0259
Echinococcus granulosus geminin 0.0337 0.7757 0.843
Echinococcus granulosus chromobox protein 2 0.0012 0.008 0.0075
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0294 0.045
Echinococcus multilocularis aryl hydrocarbon receptor 0.0012 0.0097 0.0094
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0031 0.0549 0.0852
Schistosoma mansoni nAChR subunit 0.0026 0.0418 0.0386
Loa Loa (eye worm) hypothetical protein 0.0014 0.0144 0.0194
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0012 0.0089 0.0114
Schistosoma mansoni cpg binding protein 0.003 0.0504 0.0479
Plasmodium falciparum calcium-dependent protein kinase 1 0.0031 0.0549 0.0473
Echinococcus granulosus glycine receptor subunit beta 0.0026 0.0418 0.0444
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0117 0.0155
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0902 0.1299
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.1324 0.2073
Loa Loa (eye worm) serotonin transporter b 0.0015 0.0159 0.0216
Loa Loa (eye worm) cytochrome P450 0.0014 0.0132 0.0176
Brugia malayi RNA, U transporter 1 0.008 0.169 0.2649
Onchocerca volvulus 0.0014 0.0136 0.0156
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0114
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0252 0.5737 0.9026
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0633 0.1334
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Loa Loa (eye worm) sugar transporter 0.0102 0.2207 0.3199
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0902 0.1409
Loa Loa (eye worm) hypothetical protein 0.0099 0.2132 0.309
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0551 0.1117
Onchocerca volvulus 0.0012 0.0097 0.0047
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0229 0.0238
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.5737 0.9015
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0099 0.2132 0.2262
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2115 0.3244
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0026 0.0418 0.0444
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.016 0.0128
Brugia malayi CHD4 protein 0.0013 0.0117 0.0172
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0269 0.0423
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0169 0.0172
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0342 0.5404
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0159 0.0101
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0159 0.0101
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0294 0.0442
Brugia malayi excitatory GABA receptor EXP-1A 0.0026 0.0418 0.0647
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Schistosoma mansoni carbonic anhydrase-related 0.0082 0.1745 0.1838
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0012 0.0089 0.0085
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0902 0.0916
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0269 0.0377
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0551 0.1183
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0026 0.0418 0.0647
Echinococcus multilocularis General substrate transporter 0.0087 0.1869 0.2022
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0099 0.2132 0.2262
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.016 0.0128
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0031 0.0549 0.0473
Echinococcus granulosus carbonic anhydrase 0.0082 0.1745 0.1888
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0902 0.097
Echinococcus granulosus GPCR family 2 0.0015 0.0169 0.0172
Plasmodium vivax importin-beta 2, putative 0.0028 0.0469 0.0392
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0031 0.0549 0.0721
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0026 0.0418 0.0386
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0014 0.0132 0.0016
Trichomonas vaginalis adenylate cyclase, putative 0.0012 0.0097 0.0027
Loa Loa (eye worm) hypothetical protein 0.0012 0.008 0.0101
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0159 0.0237
Onchocerca volvulus Glucosylceramidase homolog 0.0165 0.3698 1
Mycobacterium leprae putative cytochrome p450 0.0014 0.0132 0.2078
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0551 0.1183
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0159 0.0237
Brugia malayi major facilitator superfamily protein 0.0014 0.0144 0.0214
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0269 0.0377
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0551 0.0751
Onchocerca volvulus 0.0014 0.0144 0.0178
Brugia malayi hypoxia-induced factor 1 0.0147 0.3264 0.513
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0114
Entamoeba histolytica protein kinase, putative 0.0031 0.0549 0.2304
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0026 0.0418 0.0444
Echinococcus granulosus snurportin 1 0.03 0.6876 0.7471
Mycobacterium ulcerans glutaminase 0.0278 0.6355 1
Trypanosoma brucei glucose transporter, putative 0.0032 0.0551 0.1117
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.2548 0.3696
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0175 0.3934 0.4234
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0031 0.0549 0.0721
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0527 0.0504
Onchocerca volvulus 0.0026 0.0418 0.0936
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0026 0.0418 0.0444
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0144 0.0214
Schistosoma mansoni cytochrome P450 0.0014 0.0132 0.0072
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0813 0.2027
Toxoplasma gondii protein kinase, putative 0.0288 0.6595 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0114
Entamoeba histolytica hypothetical protein 0.0014 0.0136 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0144 0.0102
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0269 0.0377
Plasmodium falciparum calcium-dependent protein kinase 4 0.0031 0.0549 0.0473
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0633 0.0621
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0026 0.0418 0.0647
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0633 0.1245
Loa Loa (eye worm) hypothetical protein 0.0014 0.0136 0.0183
Loa Loa (eye worm) hypothetical protein 0.0035 0.0633 0.0907
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0175 0.3934 0.6185
Echinococcus granulosus cpg binding protein 0.003 0.0504 0.0537
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0026 0.0418 0.0444
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0269 0.0411
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0026 0.0418 0.0647
Loa Loa (eye worm) cytochrome P450 family protein 0.0051 0.1008 0.1453
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0159 0.0121
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0633 0.0678
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0344 0.042
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Brugia malayi Cation transporter family protein 0.0026 0.0418 0.0647
Schistosoma mansoni chromobox protein 0.0071 0.1476 0.1543
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0012 0.0097 0.0094
Loa Loa (eye worm) glutaminase 2 0.0278 0.6355 0.9242
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0026 0.0418 0.0444
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0026 0.0418 0.0444
Mycobacterium ulcerans beta-lactamase 0.0035 0.0633 0.0997
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0294 0.0513
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0012 0.008 0.0075
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0012 0.0097 0.0126
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2115 0.3244
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0014 0.0132 0.0259
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0269 0.0448
Loa Loa (eye worm) acetyltransferase 0.0141 0.3135 0.4551
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0469 0.0597
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0012 0.0089 0.0127
Echinococcus multilocularis nAChR subunit 0.0014 0.0136 0.0137
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0114
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0031 0.0549 0.0784
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0269 0.0301
Plasmodium falciparum protein kinase 7 0.0288 0.6595 0.6567
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.2548 0.3696
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0082 0.1745 0.2737
Onchocerca volvulus 0.0035 0.0633 0.153
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0229 0.0238
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0269 0.0423
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.1324 0.1913
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0014 0.0132 0.0207
Onchocerca volvulus 0.0012 0.0089 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0551 0.0751
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0014 0.0132 0.0259
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0014 0.0132 0.0259
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0159 0.0101
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0589 0.0916
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0056 0.1124 0.1158
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0136 0.0202
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Echinococcus granulosus single minded 2 0.0035 0.0633 0.0678
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0144 0.0102
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0012 0.0089 0.0127
Onchocerca volvulus Serine\/threonine kinase homolog 0.0098 0.2115 0.5626
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0269 0.0301
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0014 0.0132 0.0259
Schistosoma mansoni hypothetical protein 0.0012 0.008 0.0015
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0012 0.0089 0.0085
Trypanosoma brucei glucose transporter, putative 0.0032 0.0551 0.1117
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.5737 0.9015
Loa Loa (eye worm) glutaminase 0.0278 0.6355 0.9242
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0014 0.0132 0.0259
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0097 0.0027
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0031 0.0549 0.0721
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0469 0.062
Schistosoma mansoni cpg binding protein 0.0028 0.0466 0.0438
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0159 0.0161
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0014 0.0132 0.0207
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0082 0.1745 0.2737
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0098 0.2115 0.3066
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0269 0.0377
Brugia malayi Cytochrome P450 family protein 0.0051 0.1008 0.1575
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0117 0.0056
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0385 0.0308
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0549 0.0586
Loa Loa (eye worm) hypothetical protein 0.004 0.0742 0.1066
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0014 0.0132 0.0091
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0551 0.0751
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0114
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Loa Loa (eye worm) hypothetical protein 0.0099 0.2132 0.309
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0269 0.0377
Echinococcus granulosus glycine receptor subunit alpha 1 0.0026 0.0418 0.0444
Schistosoma mansoni sodium-dependent amino acid transporter 0.0015 0.0159 0.0101
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0026 0.0418 0.0444
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0496 0.0528
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0169 0.0253
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0159 0.0161
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0294 0.0329
Leishmania major cytochrome p450-like protein 0.0014 0.0132 0.0091
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.2115 0.2244
Loa Loa (eye worm) hypothetical protein 0.0014 0.0136 0.0183
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0294 0.0308
Schistosoma mansoni sugar transporter 0.0014 0.0144 0.0085
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0098 0.2115 0.229
Toxoplasma gondii facilitative glucose transporter GT1 0.0102 0.2207 0.3264
Trypanosoma cruzi hexose transporter 0.0032 0.0551 0.1183
Toxoplasma gondii hypothetical protein 0.0015 0.0159 0.0121
Brugia malayi beta-lactamase family protein 0.0035 0.0633 0.0985
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0014 0.0132 0.0259
Plasmodium falciparum importin beta, putative 0.0028 0.0469 0.0392
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0646 0.0571
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0633 0.0882
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0269 0.0281
Brugia malayi M-phase phosphoprotein, mpp8 0.0012 0.008 0.0113
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0385 0.0308
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0012 0.0094 0.0031
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0262 0.0514
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0026 0.0418 0.0594
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0026 0.0418 0.0647
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0633 0.0985
Onchocerca volvulus 0.0014 0.0144 0.0178
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0385 0.0752
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0902 0.097
Loa Loa (eye worm) hypothetical protein 0.0082 0.1745 0.2527
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0269 0.0377
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0902 0.097
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0141 0.3135 0.34
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Echinococcus granulosus carbonic anhydrase 0.0082 0.1745 0.1888
Schistosoma mansoni tar DNA-binding protein 0.0064 0.1324 0.1377
Loa Loa (eye worm) hypothetical protein 0.0014 0.0144 0.0194
Echinococcus granulosus glycine receptor subunit alpha 1 0.0026 0.0418 0.0444
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0785 0.0843
Mycobacterium ulcerans sugar transporter 0.0014 0.0144 0.0227
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.3698 0.5765
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0551 0.0751
Echinococcus granulosus General substrate transporter 0.0087 0.1869 0.2022
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0951 0.137
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0269 0.0377
Brugia malayi major facilitator superfamily protein 0.0014 0.0144 0.0214
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.3907 0.6099
Trypanosoma brucei glucose transporter, putative 0.0032 0.0551 0.1117
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0785 0.1124
Trypanosoma brucei glucose transporter, putative 0.0032 0.0551 0.1117
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0026 0.0418 0.0594
Schistosoma mansoni nAChR subunit 0.0026 0.0418 0.0386
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0089 0.0127
Loa Loa (eye worm) hypothetical protein 0.0015 0.0159 0.0216
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0159 0.0161
Echinococcus granulosus cytochrome P450 2K1 0.0014 0.0132 0.0132
Loa Loa (eye worm) solute carrier family 6 member 4 0.0015 0.0159 0.0216
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0342 0.0361
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0633 0.0882
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0385 0.0308
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0012 0.008 0.0075
Schistosoma mansoni carbonic anhydrase 0.0082 0.1745 0.1838
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0633 0.0882
Onchocerca volvulus 0.0026 0.0418 0.0936
Toxoplasma gondii hypothetical protein 0.0082 0.1745 0.2556
Schistosoma mansoni hypothetical protein 0.0082 0.1745 0.1838
Echinococcus granulosus Chromo domain 0.0012 0.008 0.0075
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.0102 0.0133
Schistosoma mansoni protein kinase 0.0031 0.0549 0.0528
Loa Loa (eye worm) ACC-1 protein 0.0026 0.0418 0.0594
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0269 0.0376
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0026 0.0418 0.0647
Schistosoma mansoni nAChR subunit 0.0012 0.0089 0.0025
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2115 0.3244
Onchocerca volvulus 0.0014 0.0144 0.0178
Mycobacterium leprae Conserved hypothetical protein 0.0014 0.0132 0.2078
Echinococcus granulosus carbonic anhydrase 0.0082 0.1745 0.1888
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0342 0.0639
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0014 0.0144 0.0227
Schistosoma mansoni neurotransmitter gated ion channel 0.0014 0.0136 0.0077
Echinococcus multilocularis chromobox protein 1 0.0071 0.1476 0.1594
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.2115 0.5261
Echinococcus multilocularis dna polymerase kappa 0.002 0.0269 0.0281
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0026 0.0418 0.0647
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0114
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0026 0.0418 0.0647
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0114
Leishmania major cytochrome p450-like protein 0.0014 0.0132 0.0091
Loa Loa (eye worm) hypothetical protein 0.0015 0.0159 0.0216
Giardia lamblia Kinase, PLK 0.0098 0.2115 1
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0646 0.0571
Brugia malayi RNA binding protein 0.0064 0.1324 0.2073
Loa Loa (eye worm) TAR-binding protein 0.0064 0.1324 0.1913
Onchocerca volvulus 0.0012 0.0094 0.004
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0951 0.1486
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0026 0.0418 0.0386
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0026 0.0418 0.0594
Trypanosoma brucei polo-like protein kinase 0.0098 0.2115 0.5225
Trypanosoma brucei glucose transporter, putative 0.0032 0.0551 0.1117
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0014 0.0132 0.0207
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0089 0.0127
Trichomonas vaginalis glucose transporter, putative 0.0014 0.0144 0.0102
Echinococcus granulosus dna polymerase kappa 0.002 0.0269 0.0281
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0269 0.0377
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0014 0.0132 0.0207
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0269 0.0448
Onchocerca volvulus 0.0014 0.0144 0.0178
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0066 0.006
Brugia malayi Sugar transporter family protein 0.0102 0.2207 0.3464
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0342 0.0539
Onchocerca volvulus 0.0014 0.0144 0.0178
Loa Loa (eye worm) hypothetical protein 0.0035 0.0633 0.0907
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.3698 0.5765
Brugia malayi hypothetical protein 0.0012 0.0089 0.0127
Schistosoma mansoni hypothetical protein 0.0014 0.0132 0.0072
Loa Loa (eye worm) hypothetical protein 0.0031 0.054 0.0771
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Echinococcus multilocularis solute carrier family 22 0.0014 0.0144 0.0145
Entamoeba histolytica Ran family GTPase 0.0021 0.0294 0.1052
Onchocerca volvulus Putative nachr subunit 0.0026 0.0418 0.0936
Loa Loa (eye worm) hypothetical protein 0.0023 0.0342 0.0483
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0026 0.0418 0.0594
Loa Loa (eye worm) acetylcholine receptor protein 0.0012 0.0089 0.0114
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0014 0.0144 0.0283
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0026 0.0418 0.0647
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0342 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0017 0.0212 0.016
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0213 0.0304
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0014 0.0132 0.0259
Echinococcus multilocularis snurportin 1 0.03 0.6876 0.7471
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.1201 0.1295
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0229 0.0238
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0014 0.0132 0.0207
Onchocerca volvulus 0.0014 0.0144 0.0178
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0973 0.1423
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2115 0.3244
Schistosoma mansoni glucose transporter 0.0014 0.0144 0.0085
Schistosoma mansoni hypothetical protein 0.0337 0.7757 0.8421
Leishmania major glucose transporter, lmgt1 0.0032 0.0551 0.1183
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0026 0.0418 0.0647
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0269 0.0377
Leishmania major glucose transporter, lmgt3 0.0032 0.0551 0.1183
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0469 0.0902
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0785 0.0711
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0269 0.0222
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0469 0.062
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0294 0.0216
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0469 0.0499
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0026 0.0418 0.0444
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0785 0.1083
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0551 0.0751
Loa Loa (eye worm) hypothetical protein 0.0014 0.0144 0.0194
Loa Loa (eye worm) hypothetical protein 0.0082 0.1745 0.2527
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0132 0.0176
Plasmodium falciparum calcium-dependent protein kinase 3 0.0031 0.0549 0.0473
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0014 0.0136 0.0202
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.2207 0.239
Echinococcus multilocularis nAChR subunit 0.0026 0.0418 0.0444
Loa Loa (eye worm) hypothetical protein 0.0012 0.0097 0.0126
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0026 0.0418 0.0444
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0014 0.0132 0.0207
Brugia malayi Cytochrome P450 family protein 0.0014 0.0132 0.0195
Onchocerca volvulus 0.0014 0.0144 0.0178
Loa Loa (eye worm) hypothetical protein 0.0015 0.0159 0.0216
Trichomonas vaginalis guanylate cyclase, putative 0.0012 0.0097 0.0027
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0294 0.0308
Echinococcus multilocularis solute carrier family 22 0.0014 0.0144 0.0145
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0229 0.0238
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0159 0.0121
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0026 0.0418 0.0647
Echinococcus multilocularis 0.0014 0.0132 0.0132
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0527 0.0817
Schistosoma mansoni glucose transport protein 0.0102 0.2207 0.2343
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0031 0.0549 0.0473
Entamoeba histolytica hypothetical protein 0.0023 0.0344 0.1296
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0269 0.0281
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0026 0.0418 0.0386
Schistosoma mansoni acetylcholine receptor subunit beta 0.0012 0.0089 0.0025
Schistosoma mansoni chromobox protein 0.0012 0.008 0.0015
Trichomonas vaginalis chromobox protein, putative 0.0071 0.1476 0.2224
Loa Loa (eye worm) hypothetical protein 0.0012 0.008 0.0101
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0014 0.0132 0.0207
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2207 0.239
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0014 0.0136 0.0077
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0014 0.0132 0.0207
Mycobacterium leprae Probable lipase LipE 0.0035 0.0633 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Schistosoma mansoni hypothetical protein 0.0033 0.0589 0.0573
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0385 0.0752
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0031 0.0549 0.0473
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0159 0.008
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0159 0.0101
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0015 0.0159 0.0161
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0269 0.0222
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0014 0.0132 0.0259
Schistosoma mansoni protein kinase 0.0031 0.0549 0.0528
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0269 0.0448
Brugia malayi chromobox protein homolog 3 0.004 0.0742 0.1157
Echinococcus granulosus solute carrier family 22 0.0014 0.0144 0.0145
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0165 0.3692 0.5545
Echinococcus granulosus dnaJ subfamily B 0.0398 0.92 1
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0342 0.0527
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.1201 0.236
Onchocerca volvulus 0.0028 0.0466 0.1068
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2207 0.239
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0012 0.0097 0.0027
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0633 0.0882
Leishmania major DNA polymerase eta, putative 0.002 0.0269 0.0448
Loa Loa (eye worm) hypothetical protein 0.0014 0.0144 0.0194
Echinococcus granulosus chromobox protein 1 0.0071 0.1476 0.1594
Plasmodium falciparum amino acid transporter, putative 0.0015 0.0159 0.008
Leishmania major hypothetical protein, conserved 0.0014 0.0144 0.0123
Trypanosoma brucei carbonic anhydrase-like protein 0.0175 0.3934 1
Onchocerca volvulus 0.0035 0.0633 0.153
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0269 0.0377
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0549 0.0586
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0114
Onchocerca volvulus 0.0015 0.0159 0.0218
Brugia malayi Sugar transporter family protein 0.0014 0.0144 0.0214
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.1201 0.1295
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0014 0.0132 0.0207
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0012 0.0089 0.0085
Onchocerca volvulus 0.0026 0.0418 0.0936
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.1201 0.189
Brugia malayi CXXC zinc finger family protein 0.0028 0.0466 0.0722
Echinococcus multilocularis carbonic anhydrase II 0.0175 0.3934 0.4269
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0114
Schistosoma mansoni neurotransmitter gated ion channel 0.0012 0.0089 0.0025
Schistosoma mansoni DNA polymerase eta 0.002 0.0269 0.0222
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0066 0.006
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0014 0.0132 0.0207
Loa Loa (eye worm) hypoxia-induced factor 1 0.0147 0.3264 0.4739
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0342 0.0403
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0082 0.1745 0.2527
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Loa Loa (eye worm) hypothetical protein 0.0015 0.0159 0.0216
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0014 0.0144 0.0283
Echinococcus multilocularis Chromo domain 0.0012 0.008 0.0075
Brugia malayi hypothetical protein 0.0012 0.0089 0.0127
Brugia malayi hypothetical protein 0.0012 0.008 0.0113
Toxoplasma gondii sugar transporter ST1 0.0014 0.0144 0.0099
Loa Loa (eye worm) hypothetical protein 0.0014 0.0144 0.0194
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0026 0.0418 0.0444
Schistosoma mansoni carbonic anhydrase-related 0.0082 0.1745 0.1838
Echinococcus granulosus solute carrier family 22 0.0014 0.0144 0.0145
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0012 0.0089 0.0085
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0527 0.8314
Trichomonas vaginalis esterase, putative 0.0035 0.0633 0.0882
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0026 0.0418 0.0444
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0633 0.1398
Mycobacterium tuberculosis Conserved protein 0.0035 0.0633 0.1245
Plasmodium falciparum calcium-dependent protein kinase 5 0.0031 0.0549 0.0473
Loa Loa (eye worm) hypothetical protein 0.0015 0.0159 0.0216
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0229 0.0238
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.5737 0.9015
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0813 0.1169
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.03 0.6876 1
Loa Loa (eye worm) beta-lactamase 0.0035 0.0633 0.0907
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0026 0.0418 0.0594
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0551 0.0751
Plasmodium vivax CDK-related protein kinase 6, putative 0.0432 1 1
Brugia malayi hypothetical protein 0.0025 0.0385 0.0595
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.1124 0.1769
Echinococcus granulosus nAChR subunit 0.0026 0.0418 0.0444
Entamoeba histolytica protein kinase, putative 0.0031 0.0549 0.2304
Brugia malayi glutaminase DH11.1 0.0278 0.6355 1
Echinococcus multilocularis GPCR, family 2 0.0015 0.0169 0.0172
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.1138 0.1624
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0342 0.0639
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0633 0.0621
Brugia malayi Cytochrome P450 family protein 0.0014 0.0132 0.0195
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0294 0.0413
Trichomonas vaginalis guanylate cyclase, putative 0.0012 0.0097 0.0027
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2207 0.239
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Mycobacterium leprae Possible regulatory protein 0.0012 0.0097 0.153
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0014 0.0132 0.0207
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.015 0.0139
Onchocerca volvulus Putative transporter 0.0014 0.0144 0.0178
Leishmania major protein kinase, putative 0.0031 0.0549 0.1178
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0633 1
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0014 0.0136 0.0202
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0097 0.0027
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0012 0.0089 0.0085
Loa Loa (eye worm) hypothetical protein 0.0014 0.0144 0.0194
Brugia malayi Cation transporter family protein 0.0026 0.0418 0.0647
Schistosoma mansoni chromobox protein 0.0071 0.1476 0.1543
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0159 0.0161
Echinococcus granulosus glycine receptor subunit alpha 1 0.0026 0.0418 0.0444
Loa Loa (eye worm) hypothetical protein 0.0014 0.0144 0.0194
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0527 0.0817
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0704 0.3066
Loa Loa (eye worm) hypothetical protein 0.0035 0.0633 0.0907
Loa Loa (eye worm) hypothetical protein 0.0014 0.0144 0.0194
Brugia malayi Cation transporter family protein 0.0026 0.0418 0.0647
Schistosoma mansoni tar DNA-binding protein 0.0064 0.1324 0.1377
Plasmodium falciparum calcium-dependent protein kinase 2 0.0031 0.0549 0.0473
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0229 0.0238
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0026 0.0418 0.0647
Loa Loa (eye worm) hypothetical protein 0.0026 0.0418 0.0594
Loa Loa (eye worm) hypothetical protein 0.0014 0.0136 0.0183
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.0144 0.0085
Loa Loa (eye worm) ACC-1 protein 0.0026 0.0418 0.0594
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0633 0.1245
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0159 0.0121
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0159 0.0216
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.008 0.0015
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.1201 0.189
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0973 0.1423
Schistosoma mansoni cpg binding protein 0.003 0.0504 0.0479
Brugia malayi hypothetical protein 0.0015 0.0159 0.0237
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0704 0.0629
Echinococcus multilocularis solute carrier family 22 0.0014 0.0144 0.0145
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0229 0.0238
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0099 0.2132 0.2262
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0144 0.0102
Leishmania major glucose transporter, lmgt2 0.0032 0.0551 0.1183
Loa Loa (eye worm) hypothetical protein 0.002 0.0269 0.0376
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.1124 0.1212
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.2115 0.3244
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0742 0.1056
Loa Loa (eye worm) hypothetical protein 0.0012 0.008 0.0101
Plasmodium vivax sugar transporter, putative 0.0014 0.0144 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0144 0.0102
Loa Loa (eye worm) hypothetical protein 0.0014 0.0136 0.0183
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0159 0.0161
Onchocerca volvulus 0.0014 0.0144 0.0178
Brugia malayi MH2 domain containing protein 0.0116 0.2548 0.4002
Schistosoma mansoni hypothetical protein 0.0015 0.0169 0.0112
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0012 0.0097 0.0027
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.1124 0.1769
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.008 0.0113
Trypanosoma brucei cytochrome P450, putative 0.0014 0.0132 0.0016
Schistosoma mansoni nAChR subunit 0.0026 0.0418 0.0386
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0646 0.1431
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0169 0.0172
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0633 0.1245
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0014 0.0132 0.0207
Loa Loa (eye worm) hypothetical protein 0.0031 0.0527 0.0752
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0012 0.0089 0.0127
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.0144 0.0145
Loa Loa (eye worm) LGC-31 protein 0.0026 0.0418 0.0594
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0026 0.0418 0.0444
Brugia malayi Heterochromatin protein 1 0.0071 0.1476 0.2312
Loa Loa (eye worm) hypothetical protein 0.0014 0.0144 0.0194
Loa Loa (eye worm) hypothetical protein 0.0014 0.0144 0.0194
Brugia malayi hypothetical protein 0.0012 0.0089 0.0127
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.1201 0.2878
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0159 0.0101
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.3698 0.5765
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0902 0.097
Echinococcus multilocularis chromobox protein 1 0.0071 0.1476 0.1594
Loa Loa (eye worm) hypothetical protein 0.0049 0.0951 0.137
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0014 0.0132 0.0259
Echinococcus granulosus importin subunit beta 1 0.0028 0.0469 0.0499
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0159 0.0216

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 0.97 uM Agonist activity at human GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay ChEMBL. 21514824

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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