Detailed information for compound 153163

Basic information

Technical information
  • TDR Targets ID: 153163
  • Name: 3-[[(2S)-azetidin-2-yl]methoxy]-6-chloropyrid azine
  • MW: 199.637 | Formula: C8H10ClN3O
  • H donors: 1 H acceptors: 2 LogP: 0.88 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(nn1)OC[C@@H]1CCN1
  • InChi: 1S/C8H10ClN3O/c9-7-1-2-8(12-11-7)13-5-6-3-4-10-6/h1-2,6,10H,3-5H2/t6-/m0/s1
  • InChiKey: QLBLHFJASFCJPK-LURJTMIESA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[[(2S)-azetidin-2-yl]methoxy]-6-chloro-pyridazine
  • 3-[[(2S)-2-azetidinyl]methoxy]-6-chloropyridazine

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Neuronal acetylcholine receptor; alpha4/beta2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica serine/threonine kinase, putative 0.0059 0.0068 0.0395
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0112 0.0172 0.017
Echinococcus granulosus retinal guanylyl cyclase 2 0.0059 0.0068 0.0079
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0112 0.0172 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0102 0.0609
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0068 0.0395
Brugia malayi regulator of G-protein signaling rgs-7 0.0828 0.1581 0.1579
Echinococcus granulosus myotubularin protein 13 0.0076 0.0102 0.0119
Echinococcus granulosus exocyst complex component 2 0.0172 0.0291 0.0345
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Trypanosoma cruzi hypothetical protein 0.0076 0.0102 0.7049
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0059 0.0068 0.0066
Onchocerca volvulus 0.0059 0.0068 0.0371
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0096 0.0142 1
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Loa Loa (eye worm) RGC/RGC protein kinase 0.0059 0.0068 0.0066
Schistosoma mansoni serine/threonine-protein kinase 0.0096 0.0142 0.014
Loa Loa (eye worm) TK/FER protein kinase 0.0059 0.0068 0.0066
Schistosoma mansoni aldehyde dehydrogenase 0.0054 0.0058 0.0055
Loa Loa (eye worm) TK/FER protein kinase 0.0059 0.0068 0.0066
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0076 0.0102 0.0099
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0076 0.0102 0.0099
Schistosoma mansoni dynamin 0.0076 0.0102 0.0099
Plasmodium vivax tyrosine kinase-like protein, putative 0.0059 0.0068 0.4708
Schistosoma mansoni vav2 0.0076 0.0102 0.0099
Loa Loa (eye worm) sema domain-containing protein 0.0392 0.0725 0.0722
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0044 0.0038 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Echinococcus granulosus retinal guanylyl cyclase 2 0.0059 0.0068 0.0079
Trypanosoma cruzi hypothetical protein 0.0076 0.0102 0.7049
Echinococcus granulosus c src tyrosine kinase 0.0059 0.0068 0.0079
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0172 0.0291 0.1808
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Onchocerca volvulus 0.0059 0.0068 0.0371
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0068 0.0395
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0059 0.0068 0.0395
Schistosoma mansoni cell adhesion molecule 0.0117 0.0183 0.018
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0076 0.0102 0.0609
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Schistosoma mansoni hypothetical protein 0.0076 0.0102 0.0099
Entamoeba histolytica hypothetical protein 0.0828 0.1581 1
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0082 0.0113 0.0132
Schistosoma mansoni protein kinase 0.0059 0.0068 0.0066
Schistosoma mansoni hypothetical protein 0.0059 0.0068 0.0066
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0059 0.0068 0.0066
Brugia malayi latrophilin 2 splice variant baaae 0.003 0.0011 0.0008
Schistosoma mansoni axis inhibition protein axin 0.0828 0.1581 0.1579
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0172 0.0291 0.1808
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.008 0.011 0.0108
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Plasmodium falciparum protein kinase, putative 0.0079 0.0108 0.7587
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0076 0.0102 0.0609
Echinococcus granulosus cytohesin 1 0.0076 0.0102 0.0119
Onchocerca volvulus 0.0059 0.0068 0.0371
Echinococcus granulosus tyrosine protein kinase HCK 0.0059 0.0068 0.0079
Entamoeba histolytica hypothetical protein 0.0828 0.1581 1
Onchocerca volvulus 0.0059 0.0068 0.0371
Echinococcus multilocularis FL cytokine receptor 0.0059 0.0068 0.0079
Plasmodium falciparum tyrosine kinase-like protein 0.0059 0.0068 0.4708
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.008 0.011 0.0129
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0042 0.0035 0.0033
Onchocerca volvulus Tyrosine kinase homolog 0.0059 0.0068 0.0371
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0076 0.0102 0.0119
Loa Loa (eye worm) TK/CSK protein kinase 0.0059 0.0068 0.0066
Echinococcus granulosus calcium dependent secretion activator 1 0.0076 0.0102 0.0119
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0102 0.0609
Brugia malayi Uncoordinated protein 104 0.0076 0.0102 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0102 0.0609
Trichomonas vaginalis protein kinase atn1, putative 0.0059 0.0068 0.0395
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0096 0.0142 1
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0112 0.0172 0.017
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Echinococcus multilocularis Regulator of G protein signaling 20 0.0828 0.1581 0.1887
Schistosoma mansoni protein tyrosine kinase 0.0059 0.0068 0.0066
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0059 0.0068 0.0079
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0059 0.0068 0.0395
Loa Loa (eye worm) TK/FER protein kinase 0.0059 0.0068 0.0066
Echinococcus granulosus aurora kinase A 0.0082 0.0113 0.0132
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0031 0.0014 0.0014
Echinococcus multilocularis tyrosine protein kinase csk 0.0059 0.0068 0.0079
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Loa Loa (eye worm) TK protein kinase 0.0059 0.0068 0.0066
Loa Loa (eye worm) TK protein kinase 0.0059 0.0068 0.0066
Brugia malayi hypothetical protein 0.0117 0.0183 0.018
Echinococcus granulosus regulator of G protein signaling 7 0.0828 0.1581 0.1887
Trichomonas vaginalis centaurin/arf, putative 0.0076 0.0102 0.0609
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0059 0.0068 0.0079
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0028 0.0007 0.0005
Trypanosoma brucei aurora B kinase 0.0082 0.0113 0.7964
Loa Loa (eye worm) hypothetical protein 0.0059 0.0068 0.0066
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0082 0.0113 0.793
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Entamoeba histolytica PH domain containing protein kinase, putative 0.0096 0.0142 0.0864
Entamoeba histolytica receptor protein kinase, putative 0.0059 0.0068 0.0395
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0291 0.1808
Trypanosoma cruzi PH domain containing protein, putative 0.0076 0.0102 0.7049
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0059 0.0068 0.0079
Echinococcus granulosus tyrosine kinase 0.0059 0.0068 0.0079
Entamoeba histolytica hypothetical protein 0.0076 0.0102 0.0609
Echinococcus granulosus oxysterol binding protein 3 0.0076 0.0102 0.0119
Entamoeba histolytica hypothetical protein 0.0076 0.0102 0.0609
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0076 0.0102 0.0099
Echinococcus granulosus fibroblast growth factor receptor 4 0.0059 0.0068 0.0079
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.008 0.011 0.0129
Echinococcus multilocularis tyrosine protein kinase shark 0.0059 0.0068 0.0079
Entamoeba histolytica hypothetical protein 0.0059 0.0068 0.0395
Echinococcus granulosus integrin linked protein kinase 0.0059 0.0068 0.0079
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0082 0.0113 0.0681
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0076 0.0102 0.7121
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0059 0.0068 0.0066
Brugia malayi C-terminal src kinase protein 1 0.0059 0.0068 0.0066
Brugia malayi Plexin repeat family protein 0.0926 0.1774 0.1772
Loa Loa (eye worm) jmjC domain-containing protein 0.0031 0.0013 0.0011
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0059 0.0068 0.0079
Loa Loa (eye worm) hypothetical protein 0.0031 0.0014 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Brugia malayi SH2 domain containing protein 0.0059 0.0068 0.0066
Entamoeba histolytica hypothetical protein 0.0059 0.0068 0.0395
Schistosoma mansoni serine/threonine-protein kinase 0.0096 0.0142 0.014
Brugia malayi Guanylyl cyclase protein 23 0.0059 0.0068 0.0066
Trypanosoma brucei protein kinase, putative 0.0096 0.0142 1
Loa Loa (eye worm) hypothetical protein 0.0229 0.0403 0.0401
Loa Loa (eye worm) hypothetical protein 0.0059 0.0068 0.0066
Giardia lamblia Protein 21.1 0.0059 0.0068 0.5937
Schistosoma mansoni protein kinase 0.0079 0.0108 0.0106
Onchocerca volvulus 0.0059 0.0068 0.0371
Brugia malayi PH domain containing protein 0.0076 0.0102 0.0099
Loa Loa (eye worm) AGC/AKT protein kinase 0.0096 0.0142 0.014
Onchocerca volvulus 0.0076 0.0102 0.0561
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0079 0.0108 0.7587
Echinococcus granulosus tyrosine protein kinase shark 0.0059 0.0068 0.0079
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Echinococcus multilocularis tyrosine protein kinase csk 0.0059 0.0068 0.0079
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0828 0.1581 0.1579
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Loa Loa (eye worm) hypothetical protein 0.0392 0.0725 0.0722
Loa Loa (eye worm) serine/threonine protein kinase 0.0059 0.0068 0.0066
Schistosoma mansoni ephrin receptor 0.0064 0.0078 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0102 0.0609
Onchocerca volvulus outspread protein homolog 0.0076 0.0102 0.0561
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Schistosoma mansoni hypothetical protein 0.0392 0.0725 0.0722
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Schistosoma mansoni regulator of G protein signaling 0.0828 0.1581 0.1579
Loa Loa (eye worm) TK/FER protein kinase 0.0059 0.0068 0.0066
Schistosoma mansoni protein kinase 0.0082 0.0113 0.0111
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0054 0.0058 0.3913
Brugia malayi SRC-1 0.0059 0.0068 0.0066
Echinococcus granulosus tyrosine protein kinase csk 0.0059 0.0068 0.0079
Entamoeba histolytica protein kinase, putative 0.0082 0.0113 0.0681
Echinococcus granulosus twitchin 0.0132 0.0213 0.0251
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Entamoeba histolytica tyrosine kinase, putative 0.0059 0.0068 0.0395
Onchocerca volvulus 0.0059 0.0068 0.0371
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Loa Loa (eye worm) AGC/PKG protein kinase 0.0026 0.0003 0.0001
Trypanosoma cruzi hypothetical protein 0.0076 0.0102 0.7049
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0059 0.0068 0.0079
Loa Loa (eye worm) hypothetical protein 0.0392 0.0725 0.0722
Toxoplasma gondii protein kinase domain-containing protein 0.0096 0.0142 1
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0003 0.0001
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0076 0.0102 0.0609
Trypanosoma cruzi hypothetical protein 0.0076 0.0102 0.7049
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0059 0.0068 0.0079
Loa Loa (eye worm) hypothetical protein 0.0828 0.1581 0.1579
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0096 0.0142 1
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0096 0.0142 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0059 0.0068 0.0066
Echinococcus multilocularis transfer RNA-Thr 0.0059 0.0068 0.0079
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Brugia malayi Furin-like cysteine rich region family protein 0.0059 0.0068 0.0066
Loa Loa (eye worm) TK/FER protein kinase 0.0059 0.0068 0.0066
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Brugia malayi probable spectrin beta chain 0.0076 0.0102 0.0099
Echinococcus granulosus oxysterol binding protein 1 0.0076 0.0102 0.0119
Echinococcus granulosus semaphorin 5B 0.0392 0.0725 0.0863
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0076 0.0102 0.0119
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Loa Loa (eye worm) hypothetical protein 0.0112 0.0172 0.017
Loa Loa (eye worm) AUR protein kinase 0.0082 0.0113 0.0111
Schistosoma mansoni fibrocystin l 0.0172 0.0291 0.0288
Trichomonas vaginalis conserved hypothetical protein 0.0828 0.1581 1
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Onchocerca volvulus 0.0059 0.0068 0.0371
Loa Loa (eye worm) hypothetical protein 0.0172 0.0291 0.0288
Brugia malayi ephrin receptor 1 precursor 0.0059 0.0068 0.0066
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Echinococcus granulosus natriuretic peptide receptor 1 0.0059 0.0068 0.0079
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0059 0.0068 0.0079
Echinococcus granulosus ephrin type A receptor 4 A 0.0059 0.0068 0.0079
Loa Loa (eye worm) TK/ROR protein kinase 0.0059 0.0068 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0291 0.1808
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0076 0.0102 0.0119
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0102 0.0609
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Entamoeba histolytica tyrosine kinase, putative 0.0059 0.0068 0.0395
Echinococcus multilocularis oxysterol binding protein 1 0.0076 0.0102 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0102 0.0609
Trichomonas vaginalis centaurin alpha, putative 0.0076 0.0102 0.0609
Echinococcus multilocularis protein KINase family member (kin 25) 0.0059 0.0068 0.0079
Echinococcus granulosus dynamin 1 0.0076 0.0102 0.0119
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Echinococcus multilocularis tyrosine protein kinase HCK 0.0059 0.0068 0.0079
Echinococcus granulosus receptor type guanylyl cyclase 0.0059 0.0068 0.0079
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0068 0.0395
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Onchocerca volvulus 0.0036 0.0024 0.0122
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0096 0.0142 1
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0102 0.0609
Loa Loa (eye worm) hypothetical protein 0.0926 0.1774 0.1772
Loa Loa (eye worm) hypothetical protein 0.0036 0.0024 0.0022
Brugia malayi integrin-linked kinase 0.0059 0.0068 0.0066
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0059 0.0068 0.0066
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Entamoeba histolytica serine/threonine kinase, putative 0.0059 0.0068 0.0395
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0059 0.0068 0.0079
Onchocerca volvulus 0.0059 0.0068 0.0371
Schistosoma mansoni protein kinase 0.0059 0.0068 0.0066
Schistosoma mansoni protein kinase 0.0059 0.0068 0.0066
Schistosoma mansoni hypothetical protein 0.0076 0.0102 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Brugia malayi hypothetical protein 0.0059 0.0068 0.0066
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0059 0.0068 0.0066
Leishmania major folate/biopterin transporter, putative 0.0096 0.0142 1
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0096 0.0142 1
Echinococcus granulosus Oxysterol binding protein 11 0.0076 0.0102 0.0119
Toxoplasma gondii hypothetical protein 0.0076 0.0102 0.7121
Schistosoma mansoni plexin 0.0926 0.1774 0.1772
Echinococcus multilocularis actin binding protein anillin 0.0076 0.0102 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0291 0.1808
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0096 0.0142 1
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0076 0.0102 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Schistosoma mansoni hypothetical protein 0.0031 0.0014 0.0012
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0059 0.0068 0.0066
Schistosoma mansoni jumonji domain containing protein 0.0066 0.0083 0.008
Entamoeba histolytica protein kinase, putative 0.0096 0.0142 0.0864
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0076 0.0102 0.0099
Brugia malayi Protein kinase domain containing protein 0.0319 0.0581 0.0579
Echinococcus multilocularis raf serine:threonine protein kinase 0.0059 0.0068 0.0079
Brugia malayi Protein kinase domain containing protein 0.0096 0.0142 0.014
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0068 0.0066
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0059 0.0068 0.0079
Brugia malayi Dynamin 0.0076 0.0102 0.0099
Echinococcus multilocularis epidermal growth factor receptor 0.0059 0.0068 0.0079
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Echinococcus granulosus cGMP dependent protein kinase 1 0.0026 0.0003 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0113 0.0681
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Entamoeba histolytica hypothetical protein 0.0059 0.0068 0.0395
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0059 0.0068 0.0395
Onchocerca volvulus 0.0059 0.0068 0.0371
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0096 0.0142 1
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0059 0.0068 0.0066
Toxoplasma gondii aurora kinase 0.0082 0.0113 0.793
Schistosoma mansoni serine/threonine RGC 0.0059 0.0068 0.0066
Echinococcus multilocularis Pleckstrin y 0.0076 0.0102 0.0119
Entamoeba histolytica tyrosine kinase, putative 0.0059 0.0068 0.0395
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0059 0.0068 0.0079
Loa Loa (eye worm) TK/FAK protein kinase 0.0059 0.0068 0.0066
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0043 0.004
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.008 0.011 0.0108
Entamoeba histolytica PH domain containing protein 0.0076 0.0102 0.0609
Toxoplasma gondii Oxysterol-binding protein 0.0076 0.0102 0.7121
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0068 0.0395
Echinococcus multilocularis rac serine:threonine kinase 0.0096 0.0142 0.0167
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.4278 0.8371 0.837
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0028 0.0007 0.0005
Echinococcus multilocularis calcium dependent secretion activator 1 0.0076 0.0102 0.0119
Trichomonas vaginalis centaurin gamma, putative 0.0076 0.0102 0.0609
Echinococcus multilocularis Rho GTPase activating protein 24 0.0076 0.0102 0.0119
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Entamoeba histolytica tyrosine kinase, putative 0.0059 0.0068 0.0395
Loa Loa (eye worm) hypothetical protein 0.0031 0.0014 0.0011
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Echinococcus granulosus tyrosine protein kinase Blk 0.0059 0.0068 0.0079
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Echinococcus multilocularis transcription factor collier 0.0172 0.0291 0.0345
Leishmania major hypothetical protein, conserved 0.0059 0.0068 0.4669
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0076 0.0102 0.0609
Echinococcus multilocularis protein kinase 0.0059 0.0068 0.0079
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0059 0.0068 0.0079
Echinococcus multilocularis tyrosine protein kinase csk 0.0059 0.0068 0.0079
Loa Loa (eye worm) hypothetical protein 0.0117 0.0183 0.018
Loa Loa (eye worm) hypothetical protein 0.0059 0.0068 0.0066
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0076 0.0102 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0068 0.0066
Brugia malayi Variant SH3 domain containing protein 0.0076 0.0102 0.0099
Loa Loa (eye worm) hypothetical protein 0.0112 0.0172 0.017
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0076 0.0102 0.0119
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0113 0.0111
Brugia malayi Cadps2 protein 0.0076 0.0102 0.0099
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Echinococcus multilocularis regulator of G protein signaling 3 0.0828 0.1581 0.1887
Brugia malayi PH domain containing protein 0.0076 0.0102 0.0099
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0828 0.1581 0.1887
Trichomonas vaginalis protein tyrosine kinase, putative 0.0059 0.0068 0.0395
Brugia malayi A-kinase anchor protein 10, precursor 0.0828 0.1581 0.1579
Entamoeba histolytica receptor protein kinase, putative 0.0059 0.0068 0.0395
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0059 0.0068 0.0371
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0059 0.0068 0.0079
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0096 0.0142 1
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0026 0.0003 0.0001
Brugia malayi PH domain containing protein 0.0076 0.0102 0.0099
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0079 0.0108 0.7626
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Echinococcus granulosus transcription factor collier 0.0172 0.0291 0.0345
Entamoeba histolytica hypothetical protein 0.0076 0.0102 0.0609
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Loa Loa (eye worm) hypothetical protein 0.0059 0.0068 0.0066
Echinococcus granulosus activated cdc42 kinase 1 0.0059 0.0068 0.0079
Leishmania major protein kinase, putative 0.0096 0.0142 1
Echinococcus multilocularis protein tyrosine kinase 0.0059 0.0068 0.0079
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Echinococcus multilocularis tyrosine protein kinase Srms 0.0059 0.0068 0.0079
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0076 0.0102 0.0119
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0079 0.0108 0.0127
Toxoplasma gondii protein kinase 0.0059 0.0068 0.4708
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0172 0.0291 0.1808
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0059 0.0068 0.0066
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0059 0.0068 0.0079
Loa Loa (eye worm) TK/FER protein kinase 0.0059 0.0068 0.0066
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0059 0.0068 0.0079
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0059 0.0068 0.0079
Loa Loa (eye worm) hypothetical protein 0.0112 0.0172 0.017
Schistosoma mansoni hypothetical protein 0.0533 0.1001 0.0999
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0059 0.0068 0.0079
Brugia malayi SH2 domain containing protein 0.0059 0.0068 0.0066
Leishmania major protein kinase, putative 0.0082 0.0113 0.7915
Loa Loa (eye worm) TK/ALK protein kinase 0.0319 0.0581 0.0578
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0059 0.0068 0.0395
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0059 0.0068 0.0079
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Echinococcus multilocularis DCC interacting protein 13 beta 0.0076 0.0102 0.0119
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0076 0.0102 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Plasmodium falciparum serine/threonine protein kinase, putative 0.0082 0.0113 0.793
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0113 0.0681
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Echinococcus multilocularis GRB2 associated binding protein 3 0.0076 0.0102 0.0119
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0059 0.0068 0.4708
Brugia malayi Immunoglobulin I-set domain containing protein 0.0117 0.0183 0.018
Toxoplasma gondii AtPH1 family protein 0.0076 0.0102 0.7121
Entamoeba histolytica hypothetical protein 0.0059 0.0068 0.0395
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0059 0.0068 0.0079
Brugia malayi Regulator of G protein signaling domain containing protein 0.0828 0.1581 0.1579
Echinococcus multilocularis epidermal growth factor receptor 0.0059 0.0068 0.0079
Brugia malayi jmjC domain containing protein 0.0083 0.0116 0.0114
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0054 0.0058 0.0066
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0076 0.0102 0.0609
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0059 0.0068 0.0079
Entamoeba histolytica tyrosine kinase, putative 0.0059 0.0068 0.0395
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Entamoeba histolytica tyrosine kinase, putative 0.0059 0.0068 0.0395
Entamoeba histolytica protein kinase, putative 0.0096 0.0142 0.0864
Brugia malayi Tyrosine-protein kinase abl-1 0.0059 0.0068 0.0066
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0076 0.0102 0.7049
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Echinococcus granulosus MAM 0.0031 0.0014 0.0014
Plasmodium vivax PH domain containing protein 0.0076 0.0102 0.7121
Schistosoma mansoni vesicular amine transporter 0.0115 0.0178 0.0176
Entamoeba histolytica PH domain containing protein kinase, putative 0.0096 0.0142 0.0864
Trichomonas vaginalis centaurin/arf, putative 0.0076 0.0102 0.0609
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0172 0.0291 0.1808
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0059 0.0068 0.0066
Loa Loa (eye worm) TK/FER protein kinase 0.0059 0.0068 0.0066
Trichomonas vaginalis hypothetical protein 0.0076 0.0102 0.0609
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0059 0.0068 0.0079
Entamoeba histolytica PH domain containing protein kinase, putative 0.0096 0.0142 0.0864
Schistosoma mansoni jumonji/arid domain-containing protein 0.0031 0.0013 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0076 0.0102 0.0609
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0076 0.0102 0.0609
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0076 0.0102 0.7049
Onchocerca volvulus 0.0059 0.0068 0.0371
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.008 0.011 0.0108
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Brugia malayi PH domain containing protein 0.0076 0.0102 0.0099
Schistosoma mansoni growth factor receptor-bound protein 0.0076 0.0102 0.0099
Brugia malayi hypothetical protein 0.0828 0.1581 0.1579
Echinococcus multilocularis neuroglian 0.0112 0.0172 0.0203
Loa Loa (eye worm) MH2 domain-containing protein 0.0204 0.0353 0.0351
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0102 0.0609
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0059 0.0068 0.0395
Echinococcus multilocularis tyrosine protein kinase Blk 0.0059 0.0068 0.0079
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0068 0.0395
Schistosoma mansoni protein kinase 0.0079 0.0108 0.0106
Onchocerca volvulus 0.0059 0.0068 0.0371
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Onchocerca volvulus 0.0076 0.0102 0.0561
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Brugia malayi protein-tyrosine kinase 0.0059 0.0068 0.0066
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0096 0.0142 1
Loa Loa (eye worm) TK/DDR protein kinase 0.0059 0.0068 0.0066
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Entamoeba histolytica PH domain containing protein kinase, putative 0.0096 0.0142 0.0864
Schistosoma mansoni rho gtpase activating protein 0.0076 0.0102 0.0099
Trichomonas vaginalis TK family protein kinase 0.0059 0.0068 0.0395
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Toxoplasma gondii aldehyde dehydrogenase 0.0054 0.0058 0.3957
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Brugia malayi PH domain containing protein 0.0076 0.0102 0.0099
Brugia malayi Plekhf2 protein 0.0076 0.0102 0.0099
Plasmodium falciparum cGMP-dependent protein kinase 0.0026 0.0003 0.0072
Echinococcus granulosus tyrosine protein kinase pr2 0.0059 0.0068 0.0079
Giardia lamblia Aurora kinase 0.0082 0.0113 1
Loa Loa (eye worm) transcription factor SMAD2 0.0204 0.0353 0.0351
Entamoeba histolytica hypothetical protein 0.0059 0.0068 0.0395
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0059 0.0068 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0291 0.1808
Loa Loa (eye worm) syntrophin-1 0.0076 0.0102 0.0099
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Entamoeba histolytica hypothetical protein 0.0096 0.0142 0.0864
Echinococcus granulosus Regulator of G protein signaling 20 0.0828 0.1581 0.1887
Trypanosoma cruzi hypothetical protein 0.0076 0.0102 0.7049
Schistosoma mansoni axis inhibition protein axin 0.0828 0.1581 0.1579
Loa Loa (eye worm) TK/Met protein kinase 0.0059 0.0068 0.0066
Schistosoma mansoni zinc finger protein 0.0076 0.0102 0.0099
Toxoplasma gondii hypothetical protein 0.0076 0.0102 0.7121
Echinococcus granulosus tyrosine protein kinase Srms 0.0059 0.0068 0.0079
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Echinococcus multilocularis cytohesin 1 0.0076 0.0102 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Entamoeba histolytica hypothetical protein 0.0059 0.0068 0.0395
Entamoeba histolytica protein kinase domain containing protein 0.0082 0.0113 0.0681
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0076 0.0102 0.0119
Echinococcus multilocularis regulator of G protein signaling 7 0.0828 0.1581 0.1887
Brugia malayi Oxysterol-binding protein 0.0076 0.0102 0.0099
Echinococcus granulosus regulator of G protein signaling 3 0.0828 0.1581 0.1887
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Schistosoma mansoni protein kinase 0.0059 0.0068 0.0066
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.008 0.011 0.0129
Echinococcus granulosus pdz domain containing protein 0.0076 0.0102 0.0119
Entamoeba histolytica protein kinase, putative 0.0096 0.0142 0.0864
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0096 0.0142 1
Brugia malayi Oxysterol binding protein 0.0076 0.0102 0.0099
Echinococcus multilocularis plexin a4 0.1097 0.2112 0.2521
Brugia malayi MH2 domain containing protein 0.0204 0.0353 0.0351
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0007 0.0008
Trypanosoma cruzi aurora B kinase, putative 0.0082 0.0113 0.7878
Echinococcus granulosus raf serine:threonine protein kinase 0.0059 0.0068 0.0079
Brugia malayi plexin A 0.1097 0.2112 0.211
Echinococcus granulosus regulator of G protein signaling 3 0.0828 0.1581 0.1887
Onchocerca volvulus 0.0392 0.0725 0.4078
Onchocerca volvulus 0.0076 0.0102 0.0561
Echinococcus granulosus jumonji domain containing protein 0.0035 0.0022 0.0023
Loa Loa (eye worm) hypothetical protein 0.0044 0.0038 0.0036
Echinococcus multilocularis aurora kinase A 0.0082 0.0113 0.0132
Brugia malayi Pleckstrin Homology Domain 0.0076 0.0102 0.0099
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0076 0.0102 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0102 0.0609
Echinococcus granulosus neuroglian 0.0112 0.0172 0.0203
Trichomonas vaginalis rotamase, putative 0.0028 0.0007 0.0008
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0096 0.0142 1
Echinococcus multilocularis Ras associated and pleckstrin y 0.0076 0.0102 0.0119
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Onchocerca volvulus 0.0026 0.0003 0.0002
Schistosoma mansoni protein kinase 0.0059 0.0068 0.0066
Loa Loa (eye worm) hypothetical protein 0.0059 0.0068 0.0066
Brugia malayi Fibronectin type III domain containing protein 0.0117 0.0183 0.018
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0079 0.0108 0.7526
Brugia malayi hypothetical protein 0.0392 0.0725 0.0722
Schistosoma mansoni serine/threonine protein kinase 0.3914 0.7654 0.7653
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0059 0.0068 0.0079
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Loa Loa (eye worm) hypothetical protein 0.0044 0.0038 0.0036
Loa Loa (eye worm) hypothetical protein 0.0392 0.0725 0.0722
Onchocerca volvulus 0.0059 0.0068 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0102 0.0609
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Entamoeba histolytica cysteine surface protein, putative 0.0059 0.0068 0.0395
Onchocerca volvulus 0.0059 0.0068 0.0371
Loa Loa (eye worm) AUR protein kinase 0.0082 0.0113 0.0111
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.008 0.011 0.0108
Schistosoma mansoni tyrosine protein kinase 0.0059 0.0068 0.0066
Trypanosoma brucei Flagellum attachment zone protein 20 0.0059 0.0068 0.4794
Entamoeba histolytica hypothetical protein 0.0172 0.0291 0.1808
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0076 0.0102 0.0099
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0828 0.1581 0.1579
Entamoeba histolytica protein kinase domain containing protein 0.0231 0.0406 0.2543
Leishmania major serine/threonine-protein kinase a, putative 0.0096 0.0142 1
Echinococcus multilocularis expressed protein 0.0828 0.1581 0.1887
Plasmodium falciparum protein kinase, putative 0.0059 0.0068 0.4708
Loa Loa (eye worm) TK/ABL protein kinase 0.0059 0.0068 0.0066
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0076 0.0102 0.0561
Giardia lamblia Kinase, NEK 0.0059 0.0068 0.5937
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Echinococcus granulosus expressed protein 0.0828 0.1581 0.1887
Brugia malayi PXA domain containing protein 0.0828 0.1581 0.1579
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Entamoeba histolytica hypothetical protein 0.0059 0.0068 0.0395
Loa Loa (eye worm) TK protein kinase 0.0059 0.0068 0.0066
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0082 0.0113 0.0681
Echinococcus granulosus cGMP dependent protein kinase 0.0026 0.0003 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Echinococcus granulosus activated cdc42 kinase 1 0.0059 0.0068 0.0079
Schistosoma mansoni goodpasture antigen-binding protein 0.0076 0.0102 0.0099
Schistosoma mansoni hypothetical protein 0.0148 0.0243 0.0241
Loa Loa (eye worm) TK/FER protein kinase 0.0059 0.0068 0.0066
Schistosoma mansoni myotubularin-related protein 0.0076 0.0102 0.0099
Entamoeba histolytica PH domain containing protein kinase, putative 0.0096 0.0142 0.0864
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Entamoeba histolytica tyrosine kinase, putative 0.0059 0.0068 0.0395
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Loa Loa (eye worm) hypothetical protein 0.0059 0.0068 0.0066
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0059 0.0068 0.0079
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0059 0.0068 0.0079
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0059 0.0068 0.0079
Entamoeba histolytica p21-activated kinase 0.0096 0.0142 0.0864
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0059 0.0068 0.0079
Schistosoma mansoni serine/threonine protein kinase 0.3914 0.7654 0.7653
Entamoeba histolytica protein kinase domain containing protein 0.0079 0.0108 0.065
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Echinococcus granulosus kinase suppressor of Ras 1 0.0059 0.0068 0.0079
Echinococcus granulosus Pleckstrin y 0.0076 0.0102 0.0119
Plasmodium falciparum calcium-dependent protein kinase 7 0.0096 0.0142 1
Trypanosoma cruzi PH domain containing protein, putative 0.0076 0.0102 0.7049
Plasmodium falciparum protein kinase, putative 0.0059 0.0068 0.4708
Brugia malayi serine/threonine protein kinase 6 0.0082 0.0113 0.0111
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0059 0.0068 0.0079
Echinococcus granulosus GRB2 associated binding protein 3 0.0076 0.0102 0.0119
Trypanosoma cruzi hypothetical protein 0.0076 0.0102 0.7049
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0044 0.0038 0.0036
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0079 0.0108 0.7526
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Echinococcus multilocularis activin receptor type 0.0079 0.0108 0.0127
Echinococcus granulosus tyrosine kinase 0.0059 0.0068 0.0079
Brugia malayi jmjC domain containing protein 0.0031 0.0013 0.0011
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Entamoeba histolytica tyrosine kinase, putative 0.0059 0.0068 0.0395
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0058 0.5
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0059 0.0068 0.4708
Echinococcus granulosus Pleckstrin y 0.0076 0.0102 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Entamoeba histolytica PH domain containing protein 0.0076 0.0102 0.0609
Loa Loa (eye worm) TK protein kinase 0.0059 0.0068 0.0066
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0076 0.0102 0.0119
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Entamoeba histolytica tyrosine kinase, putative 0.0059 0.0068 0.0395
Schistosoma mansoni protein kinase 0.0059 0.0068 0.0066
Trypanosoma cruzi NIMA-related kinase, putative 0.0096 0.0142 1
Loa Loa (eye worm) hypothetical protein 0.0392 0.0725 0.0722
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0026 0.0003 0.0001
Brugia malayi regulator of G-protein signaling egl-10 0.0828 0.1581 0.1579
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Echinococcus multilocularis expressed protein 0.0028 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0112 0.0172 0.017
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0059 0.0068 0.0066
Onchocerca volvulus 0.0076 0.0102 0.0561
Loa Loa (eye worm) AUR protein kinase 0.0082 0.0113 0.0111
Echinococcus multilocularis c src tyrosine kinase 0.0059 0.0068 0.0079
Entamoeba histolytica cell surface protease gp63, putative 0.0172 0.0291 0.1808
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0029 0.0151
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0828 0.1581 0.1579
Loa Loa (eye worm) TK protein kinase 0.0059 0.0068 0.0066
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0076 0.0102 0.0609
Entamoeba histolytica ankyrin repeat protein 0.0059 0.0068 0.0395
Echinococcus multilocularis regulator of G protein signaling 0.0828 0.1581 0.1887
Schistosoma mansoni hypothetical protein 0.0172 0.0291 0.0288
Loa Loa (eye worm) RGC/RGC protein kinase 0.0059 0.0068 0.0066
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Echinococcus multilocularis hypothetical protein 0.0392 0.0725 0.0863
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Entamoeba histolytica hypothetical protein 0.0059 0.0068 0.0395
Brugia malayi hypothetical protein 0.0031 0.0014 0.0012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.008 0.011 0.0108
Loa Loa (eye worm) hypothetical protein 0.0059 0.0068 0.0066
Brugia malayi Sema domain containing protein 0.0392 0.0725 0.0722
Schistosoma mansoni hypothetical protein 0.0076 0.0102 0.0099
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0076 0.0102 0.7121
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0076 0.0102 0.0609
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Giardia lamblia Kinase 0.0059 0.0068 0.5937
Entamoeba histolytica tyrosine kinase, putative 0.0059 0.0068 0.0395
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0059 0.0068 0.0066
Loa Loa (eye worm) TK/FER protein kinase 0.0059 0.0068 0.0066
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Brugia malayi PH domain containing protein 0.0076 0.0102 0.0099
Schistosoma mansoni hypothetical protein 0.003 0.0011 0.0008
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0083 0.0116 0.0136
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0102 0.0609
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0102 0.0609
Entamoeba histolytica hypothetical protein 0.0059 0.0068 0.0395
Trypanosoma cruzi PH domain containing protein, putative 0.0076 0.0102 0.7049
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0096 0.0142 1
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0102 0.0609
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Echinococcus multilocularis tyrosine protein kinase pr2 0.0059 0.0068 0.0079
Loa Loa (eye worm) TK protein kinase 0.0059 0.0068 0.0066
Echinococcus granulosus protein kinase 0.0059 0.0068 0.0079
Loa Loa (eye worm) PH domain-containing protein 0.0076 0.0102 0.0099
Entamoeba histolytica tyrosine kinase, putative 0.0059 0.0068 0.0395
Loa Loa (eye worm) hypothetical protein 0.0117 0.0183 0.018
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0059 0.0068 0.0395
Brugia malayi hypothetical protein 0.0828 0.1581 0.1579
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0059 0.0068 0.0395
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0042 0.0035 0.0039
Echinococcus granulosus epidermal growth factor receptor 0.0059 0.0068 0.0079
Trypanosoma brucei Pseudokinase, putative 0.0059 0.0068 0.4794
Entamoeba histolytica ARF GTPase activating protein, putative 0.0076 0.0102 0.0609
Echinococcus multilocularis tyrosine protein kinase Abl 0.0059 0.0068 0.0079
Loa Loa (eye worm) hypothetical protein 0.0172 0.0291 0.0288
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0828 0.1581 0.1579
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0102 0.0609
Trichomonas vaginalis conserved hypothetical protein 0.0828 0.1581 1
Brugia malayi serine/threonine-protein kinase 6 0.0082 0.0113 0.0111
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Echinococcus multilocularis pleckstrin y domain containing family A 0.0076 0.0102 0.0119
Brugia malayi Immunoglobulin I-set domain containing protein 0.0171 0.0288 0.0286
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Echinococcus granulosus tyrosine protein kinase Lyn 0.0079 0.0108 0.0127
Loa Loa (eye worm) hypothetical protein 0.0059 0.0068 0.0066
Schistosoma mansoni centaurin alpha 0.0076 0.0102 0.0099
Trichomonas vaginalis protein transport protein sec7, putative 0.0076 0.0102 0.0609
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Loa Loa (eye worm) hypothetical protein 0.0059 0.0068 0.0066
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Trichomonas vaginalis AGC family protein kinase 0.0059 0.0068 0.0395
Plasmodium vivax protein kinase, putative 0.0059 0.0068 0.4708
Brugia malayi MAX-1A 0.0076 0.0102 0.0099
Loa Loa (eye worm) PXA domain-containing protein 0.0828 0.1581 0.1579
Entamoeba histolytica hypothetical protein, conserved 0.0076 0.0102 0.0609
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0059 0.0068 0.0395
Echinococcus granulosus geminin 0.0148 0.0243 0.0288
Brugia malayi PH domain containing protein 0.0076 0.0102 0.0099
Brugia malayi Tyrosine-protein kinase PR2 0.0059 0.0068 0.0066
Echinococcus granulosus beta-adrenergic receptor kinase 0.3914 0.7654 0.9143
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Echinococcus multilocularis beta 1 syntrophin 0.0076 0.0102 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Loa Loa (eye worm) TK protein kinase 0.0059 0.0068 0.0066
Entamoeba histolytica protein kinase, putative 0.0096 0.0142 0.0864
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0076 0.0102 0.7121
Brugia malayi TBC domain containing protein 0.0076 0.0102 0.0099
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Loa Loa (eye worm) TK/FER protein kinase 0.0059 0.0068 0.0066
Loa Loa (eye worm) hypothetical protein 0.0059 0.0068 0.0066
Onchocerca volvulus 0.0031 0.0014 0.0064
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0064 0.0078 0.0091
Schistosoma mansoni nephrin 0.0117 0.0183 0.018
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0054 0.0058 0.0066
Toxoplasma gondii peptidylprolyl isomerase 0.0027 0.0006 0.0244
Loa Loa (eye worm) TK/FER protein kinase 0.0059 0.0068 0.0066
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Loa Loa (eye worm) hypothetical protein 0.0172 0.0291 0.0288
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0059 0.0068 0.0395
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0102 0.0609
Trypanosoma cruzi protein kinase, putative 0.0059 0.0068 0.4576
Echinococcus multilocularis myotubularin protein 13 0.0076 0.0102 0.0119
Schistosoma mansoni goodpasture antigen-binding protein 0.0076 0.0102 0.0099
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Trypanosoma brucei rac serine-threonine kinase, putative 0.0096 0.0142 1
Echinococcus granulosus roundabout 2 0.0117 0.0183 0.0216
Echinococcus granulosus tyrosine protein kinase Fyn 0.0059 0.0068 0.0079
Brugia malayi PH domain containing protein 0.0076 0.0102 0.0099
Echinococcus multilocularis Pleckstrin y 0.0076 0.0102 0.0119
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0102 0.0609
Loa Loa (eye worm) hypothetical protein 0.0059 0.0068 0.0066
Entamoeba histolytica tyrosine kinase, putative 0.0059 0.0068 0.0395
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0076 0.0102 0.0609
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0076 0.0102 0.7121
Entamoeba histolytica tyrosine kinase, putative 0.0059 0.0068 0.0395
Entamoeba histolytica protein kinase, putative 0.0096 0.0142 0.0864
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0076 0.0102 0.0099
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Echinococcus granulosus Pleckstrin y 0.0076 0.0102 0.0119
Entamoeba histolytica protein kinase, putative 0.0082 0.0113 0.0681
Echinococcus granulosus regulator of G protein signaling 7 0.0828 0.1581 0.1887
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0059 0.0068 0.0079
Entamoeba histolytica hypothetical protein 0.0031 0.0014 0.0053
Leishmania major protein kinase, putative 0.0079 0.0108 0.7569
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.4278 0.8371 0.837
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0096 0.0142 1
Schistosoma mansoni regulator of G protein signaling 0.0828 0.1581 0.1579
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Trichomonas vaginalis conserved hypothetical protein 0.0828 0.1581 1
Loa Loa (eye worm) protein kinase domain-containing protein 0.0059 0.0068 0.0066
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0059 0.0068 0.0079
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0059 0.0068 0.0066
Loa Loa (eye worm) hypothetical protein 0.0828 0.1581 0.1579
Echinococcus granulosus oxysterol binding protein 9 0.0076 0.0102 0.0119
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.3914 0.7654 0.7653
Schistosoma mansoni oxysterol-binding protein 1 0.0076 0.0102 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0102 0.0609
Schistosoma mansoni aldehyde dehydrogenase 0.0054 0.0058 0.0055
Echinococcus multilocularis heat shock protein 70 0.0059 0.0068 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0102 0.0609
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0076 0.0102 0.0119
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0031 0.0014 0.0014
Onchocerca volvulus 0.0059 0.0068 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0102 0.0609
Entamoeba histolytica serine/threonine kinase, putative 0.0059 0.0068 0.0395
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0082 0.0113 0.0132
Echinococcus multilocularis jumonji domain containing protein 0.0035 0.0022 0.0023
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0059 0.0068 0.0395
Loa Loa (eye worm) RGC/RGC protein kinase 0.0059 0.0068 0.0066
Loa Loa (eye worm) TK/INSR protein kinase 0.0059 0.0068 0.0066
Leishmania major hypothetical protein, conserved 0.0076 0.0102 0.71
Onchocerca volvulus Putative zinc finger protein 0.0076 0.0102 0.0561
Loa Loa (eye worm) TK protein kinase 0.0059 0.0068 0.0066
Echinococcus multilocularis G protein coupled receptor kinase 6 0.4278 0.8371 1
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Onchocerca volvulus 0.0076 0.0102 0.0561
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Echinococcus multilocularis dynamin 1 0.0076 0.0102 0.0119
Echinococcus multilocularis natriuretic peptide receptor 1 0.0059 0.0068 0.0079
Brugia malayi bone morphogenetic protein type 1 receptor 0.0059 0.0068 0.0066
Echinococcus granulosus protein tyrosine kinase 0.0059 0.0068 0.0079
Echinococcus granulosus tyrosine protein kinase Fyn 0.0059 0.0068 0.0079
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0059 0.0068 0.0066
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Entamoeba histolytica hypothetical protein 0.0828 0.1581 1
Trypanosoma cruzi Protein kinase B 0.0096 0.0142 1
Entamoeba histolytica tyrosine kinase, putative 0.0059 0.0068 0.0395
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0043 0.004
Toxoplasma gondii phosphatidylinositol transfer protein 0.0076 0.0102 0.7121
Schistosoma mansoni protein kinase 0.0079 0.0108 0.0106
Entamoeba histolytica serine/threonine kinase, putative 0.0059 0.0068 0.0395
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Echinococcus multilocularis semaphorin 5B 0.0392 0.0725 0.0863
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0058 0.5
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0828 0.1581 1
Echinococcus granulosus tyrosine protein kinase csk 0.0059 0.0068 0.0079
Echinococcus granulosus defective proboscis extension response 0.0112 0.0172 0.0203
Loa Loa (eye worm) TK protein kinase 0.0059 0.0068 0.0066
Loa Loa (eye worm) cytohesin 3 0.0076 0.0102 0.0099
Brugia malayi hypothetical protein 0.0059 0.0068 0.0066
Echinococcus multilocularis Immunoglobulin 0.0112 0.0172 0.0203
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Echinococcus multilocularis oxysterol binding protein 3 0.0076 0.0102 0.0119
Schistosoma mansoni hypothetical protein 0.0031 0.0014 0.0011
Trichomonas vaginalis protein transport protein sec7, putative 0.0076 0.0102 0.0609
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Echinococcus multilocularis tyrosine protein kinase 0.0059 0.0068 0.0079
Echinococcus multilocularis exocyst complex component 2 0.0172 0.0291 0.0345
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0076 0.0102 0.0609
Loa Loa (eye worm) RGS-3 protein 0.0828 0.1581 0.1579
Echinococcus multilocularis receptor type guanylyl cyclase 0.0059 0.0068 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0102 0.0609
Echinococcus multilocularis tyrosine kinase 0.0059 0.0068 0.0079
Entamoeba histolytica tyrosin kinase, putative 0.0059 0.0068 0.0395
Loa Loa (eye worm) hypothetical protein 0.0112 0.0172 0.017
Brugia malayi Variant SH3 domain containing protein 0.0076 0.0102 0.0099
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0059 0.0068 0.0079
Loa Loa (eye worm) sema domain-containing protein 0.0392 0.0725 0.0722
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Trypanosoma cruzi PH domain containing protein, putative 0.0076 0.0102 0.7049
Entamoeba histolytica PH domain containing protein kinase, putative 0.0096 0.0142 0.0864
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0059 0.0068 0.0395
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0076 0.0102 0.0119
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0112 0.0172 0.0203
Loa Loa (eye worm) hypothetical protein 0.0392 0.0725 0.0722
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0102 0.0609
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0096 0.0142 1
Echinococcus multilocularis integrin linked protein kinase 0.0059 0.0068 0.0079
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0076 0.0102 0.0099
Echinococcus granulosus lysine specific demethylase 5A 0.0031 0.0013 0.0013
Loa Loa (eye worm) TK/FER protein kinase 0.0059 0.0068 0.0066
Schistosoma mansoni ephrin receptor 0.0059 0.0068 0.0066
Leishmania major hypothetical protein, conserved 0.0076 0.0102 0.71
Loa Loa (eye worm) TK/FER protein kinase 0.0059 0.0068 0.0066
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0102 0.7121
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0102 0.0609
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Entamoeba histolytica hypothetical protein 0.0172 0.0291 0.1808
Brugia malayi Raf kinase 0.0059 0.0068 0.0066
Echinococcus multilocularis roundabout 2 0.0117 0.0183 0.0216
Entamoeba histolytica hypothetical protein 0.0096 0.0142 0.0864
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0828 0.1581 0.1887
Entamoeba histolytica hypothetical protein 0.0031 0.0014 0.0053
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0076 0.0102 0.0119
Echinococcus granulosus tyrosine protein kinase Fyn 0.0059 0.0068 0.0079
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0083 0.0116 0.0136
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0291 0.1808
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Loa Loa (eye worm) hypothetical protein 0.0172 0.0291 0.0288
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0096 0.0142 0.0864
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0102 0.0609
Entamoeba histolytica tyrosin kinase, putative 0.0231 0.0406 0.2543
Echinococcus multilocularis insulin receptor 0.0059 0.0068 0.0079
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0076 0.0102 0.7121
Entamoeba histolytica tyrosin kinase, putative 0.0059 0.0068 0.0395
Schistosoma mansoni hypothetical protein 0.0031 0.0014 0.0011
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0076 0.0102 0.0609
Brugia malayi hypothetical protein 0.0392 0.0725 0.0722
Trypanosoma cruzi hypothetical protein 0.0076 0.0102 0.7049
Echinococcus granulosus retinal guanylyl cyclase 2 0.0059 0.0068 0.0079
Schistosoma mansoni regulator of G protein signaling 0.0828 0.1581 0.1579
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Loa Loa (eye worm) hypothetical protein 0.0059 0.0068 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0291 0.1808
Entamoeba histolytica serine/threonine kinase, putative 0.0059 0.0068 0.0395
Echinococcus granulosus tyrosine kinase 0.0059 0.0068 0.0079
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0096 0.0142 0.0864
Schistosoma mansoni zinc finger protein 0.0076 0.0102 0.0099
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Entamoeba histolytica hypothetical protein 0.0076 0.0102 0.0609
Echinococcus multilocularis axis inhibition protein axin 0.0828 0.1581 0.1887
Echinococcus granulosus insulin receptor 0.0059 0.0068 0.0079
Loa Loa (eye worm) RGC/RGC protein kinase 0.0059 0.0068 0.0066
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0059 0.0068 0.0066
Onchocerca volvulus Protein melted homolog 0.0076 0.0102 0.0561
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Echinococcus multilocularis protein kinase 0.0059 0.0068 0.0079
Echinococcus granulosus G protein coupled receptor kinase 1 0.3086 0.6025 0.7197
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0068 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0068 0.0395
Brugia malayi Calcitonin receptor-like protein seb-1 0.0044 0.0038 0.0036
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0059 0.0068 0.0079
Echinococcus multilocularis Pleckstrin y 0.0076 0.0102 0.0119
Echinococcus granulosus Immunoglobulin 0.0112 0.0172 0.0203
Loa Loa (eye worm) hypothetical protein 0.0828 0.1581 0.1579
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0058 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0828 0.1581 1
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0171 0.0288 0.0286
Entamoeba histolytica hypothetical protein 0.0059 0.0068 0.0395
Entamoeba histolytica serine/threonine kinase, putative 0.0059 0.0068 0.0395
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0079 0.0108 0.0127
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0076 0.0102 0.0119
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Schistosoma mansoni hypothetical protein 0.0076 0.0102 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Echinococcus multilocularis beta adrenergic receptor kinase 0.3914 0.7654 0.9143
Entamoeba histolytica tyrosine kinase, putative 0.0059 0.0068 0.0395
Trypanosoma brucei protein kinase, putative 0.0079 0.0108 0.7626
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0003 0.0001
Schistosoma mansoni plexin 0.0533 0.1001 0.0999
Loa Loa (eye worm) hypothetical protein 0.0533 0.1001 0.0999
Echinococcus granulosus axis inhibition protein axin 0.0828 0.1581 0.1887
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0042 0.0035 0.0039
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0059 0.0068 0.0079
Plasmodium falciparum PH domain-containing protein, putative 0.0076 0.0102 0.7121
Entamoeba histolytica hypothetical protein 0.0172 0.0291 0.1808
Entamoeba histolytica tyrosine kinase, putative 0.0059 0.0068 0.0395
Echinococcus multilocularis Immunoglobulin 0.0112 0.0172 0.0203
Brugia malayi Sema domain containing protein 0.0392 0.0725 0.0722
Echinococcus multilocularis geminin 0.0148 0.0243 0.0288
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0096 0.0142 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.008 0.011 0.0129
Echinococcus multilocularis kinase suppressor of Ras 1 0.0059 0.0068 0.0079
Loa Loa (eye worm) hypothetical protein 0.0117 0.0183 0.018
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0076 0.0102 0.0561
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Loa Loa (eye worm) TK/FER protein kinase 0.0059 0.0068 0.0066
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0059 0.0068 0.0066
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0059 0.0068 0.0371
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0026 0.0003 0.0072
Echinococcus granulosus tyrosine protein kinase Src42A 0.0059 0.0068 0.0079
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0059 0.0068 0.0395
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Brugia malayi DNA-binding protein LAG-1 0.0172 0.0291 0.0288
Plasmodium falciparum oxysterol-binding protein, putative 0.0076 0.0102 0.7121
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0059 0.0068 0.0395
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0068 0.0066
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0059 0.0068 0.0066
Echinococcus granulosus plexin a4 0.1097 0.2112 0.2521
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Echinococcus granulosus serine/threonine protein kinase 0.0096 0.0142 0.0167
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0059 0.0068 0.0395
Schistosoma mansoni jumonji/arid domain-containing protein 0.0031 0.0013 0.0011
Brugia malayi Regulator of G protein signaling domain containing protein 0.0828 0.1581 0.1579
Schistosoma mansoni transcription factor LCR-F1 0.0031 0.0014 0.0012
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0059 0.0068 0.0079
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Echinococcus multilocularis regulator of G protein signaling 3 0.0828 0.1581 0.1887
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0076 0.0102 0.0119
Giardia lamblia Kinase, NEK 0.0059 0.0068 0.5937
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0059 0.0068 0.0395
Echinococcus granulosus axis inhibition protein axin 0.0828 0.1581 0.1887
Trypanosoma cruzi protein kinase, putative 0.0059 0.0068 0.4576
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0059 0.0068 0.0066
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0059 0.0068 0.4794
Trichomonas vaginalis kinesin light chain, putative 0.0076 0.0102 0.0609
Toxoplasma gondii protein kinase domain-containing protein 0.0059 0.0068 0.4708
Schistosoma mansoni hypothetical protein 0.0148 0.0243 0.0241
Echinococcus granulosus tyrosine protein kinase csk 0.0059 0.0068 0.0079
Echinococcus multilocularis MAM 0.0031 0.0014 0.0014
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0096 0.0142 1
Loa Loa (eye worm) TK/FER protein kinase 0.0059 0.0068 0.0066
Echinococcus multilocularis activated cdc42 kinase 1 0.0059 0.0068 0.0079
Schistosoma mansoni semaphorin 5-related 0.0392 0.0725 0.0722
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0042 0.0035 0.0033
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0076 0.0102 0.0119
Echinococcus granulosus tyrosine protein kinase Src64B 0.0059 0.0068 0.0079
Entamoeba histolytica hypothetical protein 0.0076 0.0102 0.0609
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.4278 0.8371 1
Entamoeba histolytica hypothetical protein, conserved 0.0059 0.0068 0.0395
Echinococcus multilocularis lysine specific demethylase 5A 0.0031 0.0013 0.0013
Leishmania major protein kinase, putative 0.0059 0.0068 0.4669
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.4278 0.8371 0.837
Echinococcus multilocularis tyrosine kinase 0.0059 0.0068 0.0079
Echinococcus granulosus DCC interacting protein 13 beta 0.0076 0.0102 0.0119
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Loa Loa (eye worm) rho-GTPase-activating 0.0076 0.0102 0.0099
Echinococcus granulosus tyrosine protein kinase 0.0059 0.0068 0.0079
Schistosoma mansoni regulator of G protein signaling 0.0828 0.1581 0.1579
Brugia malayi Egg laying defective protein 4 0.0026 0.0003 0.0001
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Brugia malayi Dynamin 0.0076 0.0102 0.0099
Schistosoma mansoni hypothetical protein 0.0172 0.0291 0.0288
Trichomonas vaginalis conserved hypothetical protein 0.0828 0.1581 1
Loa Loa (eye worm) hypothetical protein 0.0392 0.0725 0.0722
Trichomonas vaginalis conserved hypothetical protein 0.0828 0.1581 1
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0113 0.0681
Loa Loa (eye worm) TK/EGFR protein kinase 0.0059 0.0068 0.0066
Onchocerca volvulus 0.0926 0.1774 1
Loa Loa (eye worm) hypothetical protein 0.0828 0.1581 0.1579
Brugia malayi hypothetical protein 0.0076 0.0102 0.0099
Brugia malayi Cytohesin 3 0.0076 0.0102 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0068 0.0395
Entamoeba histolytica PH domain containing protein 0.0076 0.0102 0.0609
Echinococcus multilocularis oxysterol binding protein 9 0.0076 0.0102 0.0119
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0059 0.0068 0.0079
Onchocerca volvulus 0.0076 0.0102 0.0561
Echinococcus granulosus tyrosine protein kinase ABL1 0.0059 0.0068 0.0079
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0059 0.0068 0.0079
Onchocerca volvulus 0.0076 0.0102 0.0561
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0076 0.0102 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0113 0.0681
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0068 0.0395
Loa Loa (eye worm) SRC-1 0.0059 0.0068 0.0066
Echinococcus multilocularis Oxysterol binding protein 11 0.0076 0.0102 0.0119
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0076 0.0102 0.0119
Schistosoma mansoni oxysterol-binding protein 1 0.0076 0.0102 0.0099
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Entamoeba histolytica hypothetical protein 0.0059 0.0068 0.0395
Schistosoma mansoni dynamin 0.0076 0.0102 0.0099
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0082 0.0113 0.0681
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0054 0.0058 0.5
Echinococcus granulosus semaphorin 1A 0.0392 0.0725 0.0863
Schistosoma mansoni hypothetical protein 0.0392 0.0725 0.0722
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Echinococcus granulosus cGMP dependent protein kinase 1 0.0026 0.0003 0.0001
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0059 0.0068 0.0395
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0064 0.0078 0.0091
Echinococcus granulosus Rho GTPase activating protein 24 0.0076 0.0102 0.0119
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0029 0.0151
Toxoplasma gondii STE kinase 0.0059 0.0068 0.4708
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0059 0.0068 0.0395
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Brugia malayi Receptor family ligand binding region containing protein 0.0059 0.0068 0.0066
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Echinococcus granulosus expressed protein 0.0028 0.0007 0.0006
Schistosoma mansoni syntrophin 0.0076 0.0102 0.0099
Loa Loa (eye worm) hypothetical protein 0.0828 0.1581 0.1579
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Trichomonas vaginalis STE family protein kinase 0.0059 0.0068 0.0395
Brugia malayi hypothetical protein 0.0031 0.0014 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0102 0.0609
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0059 0.0068 0.0066
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.5106 1 1
Schistosoma mansoni protein kinase 0.0059 0.0068 0.0066
Entamoeba histolytica tyrosine kinase, putative 0.0059 0.0068 0.0395
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0059 0.0068 0.0079
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0059 0.0068 0.0079
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0059 0.0068 0.0066
Loa Loa (eye worm) TK/FER protein kinase 0.0059 0.0068 0.0066
Echinococcus granulosus beta 1 syntrophin 0.0076 0.0102 0.0119
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0076 0.0102 0.0119
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Echinococcus multilocularis G protein coupled receptor kinase 1 0.3086 0.6025 0.7197
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0102 0.0609
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0076 0.0102 0.7121
Loa Loa (eye worm) hypothetical protein 0.0076 0.0102 0.0099
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Entamoeba histolytica hypothetical protein 0.0172 0.0291 0.1808
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Loa Loa (eye worm) TK/ACK protein kinase 0.0059 0.0068 0.0066
Loa Loa (eye worm) TK protein kinase 0.0059 0.0068 0.0066
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0059 0.0068 0.0066
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0068 0.0395
Schistosoma mansoni rotamase 0.0028 0.0007 0.0005
Loa Loa (eye worm) jmjC domain-containing protein 0.0053 0.0056 0.0053
Echinococcus granulosus epidermal growth factor receptor 0.0059 0.0068 0.0079
Brugia malayi hypothetical protein 0.0059 0.0068 0.0066
Trypanosoma brucei PH domain containing protein, putative 0.0076 0.0102 0.7168
Brugia malayi Syntrophin-1 0.0076 0.0102 0.0099
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0059 0.0068 0.0395
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Brugia malayi Probable exocyst complex component Sec5 0.0172 0.0291 0.0288
Echinococcus multilocularis axis inhibition protein axin 0.0828 0.1581 0.1887
Entamoeba histolytica hypothetical protein 0.0031 0.0014 0.0053
Schistosoma mansoni regulator of G protein signaling 0.0828 0.1581 0.1579
Entamoeba histolytica protein kinase, putative 0.0096 0.0142 0.0864
Entamoeba histolytica tyrosin kinase, putative 0.0059 0.0068 0.0395
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0059 0.0068 0.0395
Loa Loa (eye worm) hypothetical protein 0.0828 0.1581 0.1579
Loa Loa (eye worm) plexin A 0.1097 0.2112 0.211
Loa Loa (eye worm) TK/RYK protein kinase 0.0059 0.0068 0.0066
Schistosoma mansoni tyrosine kinase 0.0059 0.0068 0.0066
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Loa Loa (eye worm) hypothetical protein 0.0112 0.0172 0.017
Echinococcus multilocularis regulator of G protein signaling 7 0.0828 0.1581 0.1887
Leishmania major protein kinase, putative 0.0096 0.0142 1
Loa Loa (eye worm) Plekhf2 protein 0.0076 0.0102 0.0099
Schistosoma mansoni z-protein (S1r protein) 0.0828 0.1581 0.1579
Entamoeba histolytica protein kinase, putative 0.0096 0.0142 0.0864
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0059 0.0068 0.0079
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0076 0.0102 0.7049
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0059 0.0068 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0291 0.1808
Echinococcus granulosus pleckstrin y domain containing family A 0.0076 0.0102 0.0119
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0068 0.0066
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0027 0.0006 0.0403
Trichomonas vaginalis alpha chimerin, putative 0.0076 0.0102 0.0609
Entamoeba histolytica protein kinase, putative 0.0059 0.0068 0.0395
Schistosoma mansoni serine/threonine protein kinase 0.5106 1 1
Echinococcus multilocularis ephrin type A receptor 4 A 0.0059 0.0068 0.0079
Schistosoma mansoni hypothetical protein 0.0076 0.0102 0.0099
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0059 0.0068 0.0395
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Brugia malayi PH domain containing protein 0.0076 0.0102 0.0099
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0059 0.0068 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0102 0.0609
Brugia malayi Protein kinase domain containing protein 0.0059 0.0068 0.0066
Brugia malayi IPT/TIG domain containing protein 0.0172 0.0291 0.0288
Echinococcus granulosus activin receptor type 0.0079 0.0108 0.0127
Trichomonas vaginalis TKL family protein kinase 0.0059 0.0068 0.0395
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Echinococcus multilocularis expressed conserved protein 0.0026 0.0003 0.0001
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0059 0.0068 0.0079
Loa Loa (eye worm) TK/FER protein kinase 0.0059 0.0068 0.0066
Entamoeba histolytica hypothetical protein 0.0031 0.0014 0.0053
Plasmodium falciparum tyrosine kinase-like protein 0.0059 0.0068 0.4708
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0172 0.0291 0.1808
Schistosoma mansoni protein kinase 0.0059 0.0068 0.0066
Echinococcus multilocularis tyrosine protein kinase csk 0.0059 0.0068 0.0079
Trichomonas vaginalis centaurin beta, putative 0.0076 0.0102 0.0609
Loa Loa (eye worm) hypothetical protein 0.0031 0.0014 0.0011
Trypanosoma cruzi NIMA-related kinase, putative 0.0096 0.0142 1
Loa Loa (eye worm) oxysterol binding protein 0.0076 0.0102 0.0099
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0027 0.0006 0.0173
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0142 0.0864
Entamoeba histolytica protein kinase , putative 0.0082 0.0113 0.0681
Echinococcus multilocularis pdz domain containing protein 0.0076 0.0102 0.0119
Brugia malayi serine/threonine kinase 12 0.0082 0.0113 0.0111
Entamoeba histolytica ankyrin repeat protein 0.0059 0.0068 0.0395
Loa Loa (eye worm) TK/EPH protein kinase 0.0059 0.0068 0.0066
Loa Loa (eye worm) uncoordinated protein 104 0.0076 0.0102 0.0099
Loa Loa (eye worm) hypothetical protein 0.003 0.0011 0.0008
Onchocerca volvulus 0.0059 0.0068 0.0371
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0059 0.0068 0.0395
Brugia malayi PXA domain containing protein 0.0828 0.1581 0.1579
Plasmodium vivax tyrosine kinase-like protein, putative 0.0059 0.0068 0.4708

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 15.37 nM Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat brain synaptic membranes. ChEMBL. 10509928
Ki (binding) = 15.37 nM Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat brain synaptic membranes. ChEMBL. 10509928

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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