Detailed information for compound 1609548

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 321.37 | Formula: C20H19NO3
  • H donors: 0 H acceptors: 1 LogP: 4.32 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(OC)c(cc1/C=C\c1nccc2c1cccc2)OC
  • InChi: 1S/C20H19NO3/c1-22-18-13-20(24-3)19(23-2)12-15(18)8-9-17-16-7-5-4-6-14(16)10-11-21-17/h4-13H,1-3H3/b9-8-
  • InChiKey: IRRXVUZUTRHHKJ-HJWRWDBZSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi cruzipain precursor, putative 0.0297 0.012 0.2191
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.947 0.396 1
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.3635 0.1517 0.3831
Trypanosoma cruzi hypothetical protein, conserved 0.1315 0.0546 1
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Echinococcus granulosus tyrosine protein kinase csk 0.0029 0.0007 0.0007
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0014 0.0001 0.0003
Brugia malayi Cathepsin L-like precursor 0.02 0.0079 0.0267
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.1315 0.0546 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.012 0.0485
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0182 0.0071 0.0243
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Echinococcus granulosus cathepsin l1 0.0297 0.012 0.012
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0112 0.0042 0.8867
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0029 0.0007 0.0018
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0165 0.0064 0.0162
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0023 0.0094
Brugia malayi hypothetical protein 0.0082 0.003 0.01
Schistosoma mansoni hypothetical protein 0.0082 0.003 0.0075
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Plasmodium falciparum serine repeat antigen 9 0.0067 0.0023 0.0058
Onchocerca volvulus 0.0028 0.0007 0.0568
Echinococcus granulosus SPRY domain containing protein 0.0082 0.003 0.003
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Trypanosoma cruzi cAMP binding protein, putative 0.0014 0.0001 0.0018
Echinococcus multilocularis protein kinase 0.0029 0.0007 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Loa Loa (eye worm) TK protein kinase 0.0029 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0002 0.0735
Echinococcus granulosus radixin 0.0082 0.003 0.003
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Brugia malayi hypothetical protein 0.0082 0.003 0.01
Echinococcus granulosus SPRY domain containing protein 0.0082 0.003 0.003
Entamoeba histolytica leucine-rich repeat containing protein 0.0082 0.003 0.2471
Schistosoma mansoni voltage-gated potassium channel 0.0088 0.0032 0.0081
Loa Loa (eye worm) TK/CSK protein kinase 0.0029 0.0007 0.0024
Onchocerca volvulus 0.0029 0.0007 0.0602
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.1315 0.0546 0.1855
Loa Loa (eye worm) TK/FAK protein kinase 0.7039 0.2942 1
Onchocerca volvulus 0.0029 0.0007 0.0602
Schistosoma mansoni hypothetical protein 0.0082 0.003 0.0075
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0067 0.0023 0.0094
Echinococcus granulosus cGMP dependent protein kinase 1 0.0014 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0001 0.0018
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0023 0.0094
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Giardia lamblia Kinase 0.0029 0.0007 0.0018
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.947 0.396 1
Brugia malayi Papain family cysteine protease containing protein 0.0067 0.0023 0.0079
Entamoeba histolytica cysteine protease, putative 0.0165 0.0064 0.5352
Onchocerca volvulus 0.0029 0.0007 0.0602
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.012 0.0485
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0067 0.0023 0.0058
Brugia malayi cathepsin F-like cysteine proteinase 0.0067 0.0023 0.0079
Echinococcus granulosus activated cdc42 kinase 1 0.0029 0.0007 0.0007
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Entamoeba histolytica hypothetical protein 0.0029 0.0007 0.0602
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0003 0.0052
Loa Loa (eye worm) TK/ALK protein kinase 0.0029 0.0007 0.0024
Echinococcus multilocularis insulin receptor 0.0029 0.0007 0.0007
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0029 0.0007 0.0007
Echinococcus multilocularis merlin:moesin:ezrin:radixin 0.0082 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.02 0.0079 0.0267
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0014 0.0001 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0007 0.0024
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.1315 0.0546 0.0546
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.1315 0.0546 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0029 0.0007 0.0007
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0014 0.0001 0.0018
Entamoeba histolytica hypothetical protein 0.0067 0.0023 0.1934
Echinococcus multilocularis unc 112 protein 0.0082 0.003 0.003
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0029 0.0007 0.0018
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0165 0.0064 0.1173
Loa Loa (eye worm) hypothetical protein 0.0082 0.003 0.01
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.1315 0.0546 0.0546
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0029 0.0007 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0067 0.0023 0.0094
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0029 0.0007 0.0018
Schistosoma mansoni cathepsin s 0.0098 0.0036 0.0091
Echinococcus granulosus cGMP dependent protein kinase 0.0014 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.1315 0.0546 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.012 0.2191
Echinococcus granulosus activin receptor type 0.0029 0.0007 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.003 0.012
Loa Loa (eye worm) hypothetical protein 0.0106 0.004 0.0135
Echinococcus granulosus cathepsin b 0.0475 0.0194 0.0194
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.0003 0.0433
Entamoeba histolytica cysteine protease, putative 0.0165 0.0064 0.5352
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0297 0.012 0.0485
Brugia malayi Cathepsin L-like precursor 0.0297 0.012 0.0406
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.012 0.0485
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.1315 0.0546 0.1378
Entamoeba histolytica filopodin, putative 0.0082 0.003 0.2471
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.1315 0.0546 0.1855
Giardia lamblia Cysteine protease 0.0067 0.0023 0.0058
Toxoplasma gondii protein kinase 0.0029 0.0007 0.0018
Entamoeba histolytica hypothetical protein 0.0029 0.0007 0.0602
Loa Loa (eye worm) TK protein kinase 0.0029 0.0007 0.0024
Entamoeba histolytica filopodin, putative 0.0082 0.003 0.2471
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.012 0.0485
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Echinococcus multilocularis cathepsin b 0.0475 0.0194 0.0194
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Onchocerca volvulus 0.0082 0.003 0.2471
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0019 0.0003 0.0003
Echinococcus granulosus tyrosine protein kinase shark 0.0029 0.0007 0.0007
Echinococcus granulosus talin 0.0082 0.003 0.003
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0082 0.003 0.003
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0098 0.0036 0.0122
Echinococcus multilocularis tyrosine protein kinase shark 0.0029 0.0007 0.0007
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0007 0.0602
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0014 0.0001 0.0018
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0008 0.0142
Entamoeba histolytica cysteine protease, putative 0.0165 0.0064 0.5352
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0014 0.0001 0.0001
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0083 0.003 0.003
Loa Loa (eye worm) TK/ROR protein kinase 0.0029 0.0007 0.0024
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0003 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0014 0.0001 0.0001
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0002 0.0005
Entamoeba histolytica receptor protein kinase, putative 0.0029 0.0007 0.0602
Schistosoma mansoni ephrin receptor 0.0029 0.0007 0.0018
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.1315 0.0546 0.1378
Schistosoma mansoni hypothetical protein 0.0425 0.0173 0.0437
Echinococcus multilocularis FERM central domain 0.0082 0.003 0.003
Echinococcus granulosus unc 112 protein 0.0082 0.003 0.003
Leishmania major cathepsin L-like protease 0.0297 0.012 0.2177
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0067 0.0023 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.012 0.0485
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0297 0.012 0.0406
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Loa Loa (eye worm) hypothetical protein 0.0082 0.003 0.01
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Echinococcus multilocularis cysteine protease 0.0297 0.012 0.012
Plasmodium vivax tyrosine kinase-like protein, putative 0.0029 0.0007 0.0018
Onchocerca volvulus 0.0029 0.0007 0.0602
Brugia malayi Furin-like cysteine rich region family protein 0.0029 0.0007 0.0024
Loa Loa (eye worm) TK protein kinase 0.0029 0.0007 0.0024
Trypanosoma cruzi ribonuclease inhibitor, putative 0.0082 0.003 0.0542
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0019 0.0003 0.0003
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0002 0.0009
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.2212
Onchocerca volvulus 0.0029 0.0007 0.0602
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0007 0.0602
Leishmania major cAMP-specific phosphodiesterase, putative 0.1315 0.0546 1
Giardia lamblia Cathepsin B precursor 0.0067 0.0023 0.0058
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.1315 0.0546 0.1855
Schistosoma mansoni cathepsin F (C01 family) 0.0297 0.012 0.0302
Echinococcus multilocularis ezrin 0.0082 0.003 0.003
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0007 0.2343
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.1315 0.0546 0.2212
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0014 0.0001 0.0003
Echinococcus granulosus ezrin 0.0082 0.003 0.003
Echinococcus granulosus tyrosine protein kinase Src64B 0.0029 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Brugia malayi hypothetical protein 0.003 0.0008 0.0026
Brugia malayi integrin-linked kinase 0.0029 0.0007 0.0024
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.1315 0.0546 1
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.1378
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0002 0.004
Entamoeba histolytica cysteine proteinase 1, putative 0.0165 0.0064 0.5352
Giardia lamblia Hypothetical protein 0.1315 0.0546 0.1378
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0165 0.0064 0.0162
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0029 0.0007 0.0007
Echinococcus granulosus peptidase Clp S14 family 0.0054 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0082 0.003 0.01
Plasmodium falciparum glutathione reductase 0.0017 0.0002 0.0005
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0014 0.0001 0.0003
Leishmania major trypanothione reductase 0.0049 0.0016 0.0269
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0007 0.0024
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0001 0.0001
Onchocerca volvulus 0.0182 0.0071 0.5974
Giardia lamblia Hypothetical protein 0.0067 0.0023 0.0058
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0003 0.0013
Entamoeba histolytica cysteine proteinase, putative 0.0165 0.0064 0.5352
Brugia malayi Talin 1 0.0082 0.003 0.01
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0029 0.0007 0.0029
Entamoeba histolytica cysteine protease, putative 0.0165 0.0064 0.5352
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0067 0.0023 0.0058
Echinococcus granulosus dnaJ subfamily B 0.0425 0.0173 0.0173
Onchocerca volvulus 0.0297 0.012 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0002 0.0005
Loa Loa (eye worm) AGC/PKG protein kinase 0.0014 0.0001 0.0003
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Schistosoma mansoni Radixin 0.0082 0.003 0.0075
Schistosoma mansoni ephrin receptor 0.0029 0.0007 0.0018
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0029 0.0007 0.0007
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0029 0.0007 0.0007
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.3635 0.1517 0.3831
Echinococcus multilocularis lamin dm0 0.0028 0.0007 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0475 0.0194 0.049
Giardia lamblia Cathepsin L precursor 0.0067 0.0023 0.0058
Loa Loa (eye worm) hypothetical protein 0.02 0.0079 0.0267
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0067 0.0023 0.0058
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0003 0.0003
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Brugia malayi Moesin/ezrin/radixin homolog 1 0.0082 0.003 0.01
Echinococcus multilocularis cpg binding protein 0.0032 0.0008 0.0008
Trypanosoma cruzi protein kinase, putative 0.0029 0.0007 0.0132
Schistosoma mansoni hypothetical protein 0.0029 0.0007 0.0018
Schistosoma mansoni talin 0.0082 0.003 0.0075
Leishmania major cysteine peptidase A (CPA) 0.0297 0.012 0.2177
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.1315 0.0546 0.1378
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0014 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0007 0.0602
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0029 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0067 0.0023 0.0079
Schistosoma mansoni merlin/moesin/ezrin/radixin 0.0082 0.003 0.0075
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0165 0.0064 0.0162
Brugia malayi bone morphogenetic protein type 1 receptor 0.0029 0.0007 0.0024
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0008 0.002
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0054 0.0018 0.3734
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0014 0.0001 0.0003
Echinococcus granulosus tyrosine protein kinase Srms 0.0029 0.0007 0.0007
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0029 0.0007 0.0024
Echinococcus granulosus cathepsin L 0.0165 0.0064 0.0064
Echinococcus granulosus FERM domain containing protein 5 0.0082 0.003 0.003
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0014 0.0001 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.012 0.0485
Echinococcus multilocularis tyrosine protein kinase Abl 0.0029 0.0007 0.0007
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1315 0.0546 0.1378
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0193 0.0076 0.1376
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.003 0.0075
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.1315 0.0546 0.0546
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0014 0.0001 0.0003
Entamoeba histolytica cysteine protease, putative 0.0067 0.0023 0.1934
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.2212
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.012 0.0485
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0007 0.0024
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0082 0.003 0.01
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0029 0.0007 0.0024
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.1378
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1315 0.0546 0.1378
Onchocerca volvulus 0.0029 0.0007 0.0602
Schistosoma mansoni hypothetical protein 0.0082 0.003 0.0075
Giardia lamblia Cathepsin B precursor 0.0067 0.0023 0.0058
Trichomonas vaginalis protein MLP1, putative 0.0082 0.003 0.012
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Schistosoma mansoni hypothetical protein 0.0082 0.003 0.0075
Leishmania major cathepsin L-like protease 0.0297 0.012 0.2177
Entamoeba histolytica cysteine proteinase 2 0.0165 0.0064 0.5352
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.012 0.0485
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0002 0.0735
Onchocerca volvulus 0.0029 0.0007 0.0602
Echinococcus granulosus lamin 0.0028 0.0007 0.0007
Echinococcus multilocularis cysteine protease 0.0297 0.012 0.012
Loa Loa (eye worm) protein kinase domain-containing protein 0.0029 0.0007 0.0024
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0007 0.0602
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Brugia malayi cathepsin F-like cysteine proteinase 0.0098 0.0036 0.0122
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0029 0.0007 0.0007
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0029 0.0007 0.0132
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0007 0.0602
Echinococcus granulosus tyrosine protein kinase Fyn 0.0029 0.0007 0.0007
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0029 0.0007 0.0007
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.0003 0.0008
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0002 0.0022
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0067 0.0023 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0001 0.0004
Echinococcus granulosus FERM domain containing protein 3 0.0082 0.003 0.003
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.1315 0.0546 0.1855
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0014 0.0001 0.0003
Echinococcus granulosus myosin viia 0.0082 0.003 0.003
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.462 0.1929 0.6557
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Loa Loa (eye worm) TK protein kinase 0.0029 0.0007 0.0024
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0007 0.0023
Brugia malayi Raf kinase 0.0029 0.0007 0.0024
Echinococcus granulosus tyrosine protein kinase HCK 0.0029 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.012 0.0485
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.1315 0.0546 0.1855
Echinococcus multilocularis FERM domain containing protein 3 0.0082 0.003 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.012 0.0485
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0029 0.0007 0.0029
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0029 0.0007 0.0007
Schistosoma mansoni talin 2 0.0082 0.003 0.0075
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.2212
Echinococcus multilocularis tyrosine protein kinase 0.0029 0.0007 0.0007
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Schistosoma mansoni eyes absent homolog 0.0106 0.004 0.01
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.1315 0.0546 0.1855
Schistosoma mansoni hypothetical protein 0.0014 0.0001 0.0003
Entamoeba histolytica tyrosin kinase, putative 0.0029 0.0007 0.0602
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0003 0.0003
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0022 0.0054
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0002 0.0022
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0007 0.0602
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0002 0.0005
Schistosoma mansoni cpg binding protein 0.0032 0.0008 0.0021
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0082 0.003 0.003
Brugia malayi isocitrate dehydrogenase 0.0019 0.0003 0.001
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Loa Loa (eye worm) hypothetical protein 0.0083 0.003 0.0101
Onchocerca volvulus 0.0297 0.012 1
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0007 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.1315 0.0546 1
Brugia malayi Papain family cysteine protease containing protein 0.0165 0.0064 0.0218
Plasmodium falciparum serine repeat antigen 2 0.0067 0.0023 0.0058
Entamoeba histolytica hypothetical protein 0.0029 0.0007 0.0602
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.2212
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0054 0.0018 0.3598
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.2212
Echinococcus multilocularis tyrosine protein kinase csk 0.0029 0.0007 0.0007
Loa Loa (eye worm) TK protein kinase 0.0029 0.0007 0.0024
Echinococcus granulosus cGMP dependent protein kinase 1 0.0014 0.0001 0.0001
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0007 0.0024
Schistosoma mansoni cathepsin C 0.0067 0.0023 0.0058
Entamoeba histolytica hypothetical protein, conserved 0.0029 0.0007 0.0602
Trypanosoma cruzi Flagellar Member 6 0.0014 0.0001 0.0018
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0003 0.0008
Entamoeba histolytica cysteine protease, putative 0.0067 0.0023 0.1934
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0028 0.0007 0.1464
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0035 0.0089
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0125 0.0047 1
Entamoeba histolytica cysteine protease, putative 0.0297 0.012 1
Echinococcus granulosus ephrin type A receptor 4 A 0.0029 0.0007 0.0007
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0125 0.0047 1
Brugia malayi Protein kinase domain containing protein 0.7039 0.2942 1
Giardia lamblia Cathepsin L precursor 0.0067 0.0023 0.0058
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0003 0.0008
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0029 0.0007 0.0007
Brugia malayi fibroinase precursor 0.0067 0.0023 0.0079
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0014 0.0001 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0002 0.004
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0001 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0165 0.0064 0.1173
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0002 0.004
Echinococcus multilocularis protein KINase family member (kin 25) 0.0029 0.0007 0.0007
Plasmodium falciparum thioredoxin reductase 0.0049 0.0016 0.004
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0083 0.003 0.0075
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0007 0.0018
Plasmodium falciparum cysteine proteinase falcipain 3 0.0297 0.012 0.0302
Brugia malayi SH2 domain containing protein 0.0029 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.1315 0.0546 0.1855
Echinococcus granulosus Pleckstrin y 0.0082 0.003 0.003
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.2212
Echinococcus granulosus tyrosine kinase 0.0029 0.0007 0.0007
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0067 0.0023 0.1934
Onchocerca volvulus 0.0082 0.003 0.2471
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0007 0.0602
Onchocerca volvulus 0.0029 0.0007 0.0602
Echinococcus multilocularis tyrosine protein kinase csk 0.0029 0.0007 0.0007
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0008 0.002
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0002 0.004
Leishmania major hypothetical protein, conserved 0.003 0.0008 0.0124
Schistosoma mansoni protein tyrosine kinase 0.0029 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0241 0.0096 0.0326
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0035 0.0035
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0083 0.003 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0029 0.0007 0.0007
Mycobacterium ulcerans hypothetical protein 0.0014 0.0001 0.0338
Echinococcus granulosus tyrosine protein kinase Fyn 0.0029 0.0007 0.0007
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0081 0.0029 0.0098
Plasmodium falciparum serine repeat antigen 4 0.0067 0.0023 0.0058
Entamoeba histolytica cysteine proteinase, putative 0.02 0.0079 0.6581
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Echinococcus granulosus receptor type guanylyl cyclase 0.0029 0.0007 0.0007
Brugia malayi Cytochrome P450 family protein 0.0019 0.0003 0.001
Brugia malayi Guanylyl cyclase protein 23 0.0029 0.0007 0.0024
Brugia malayi hypothetical protein 0.0029 0.0007 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0007 0.0029
Plasmodium vivax serine-repeat antigen (SERA) 0.0067 0.0023 0.0058
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0002 0.0005
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0003 0.0052
Plasmodium falciparum serine repeat antigen 5 0.0067 0.0023 0.0058
Brugia malayi cathepsin Z-like cysteine proteinase 0.0067 0.0023 0.0079
Giardia lamblia Cysteine protease 0.0067 0.0023 0.0058
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Giardia lamblia Cathepsin L-like protease 0.0067 0.0023 0.0058
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.1315 0.0546 0.1855
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0029 0.0007 0.0007
Schistosoma mansoni peptidase Clp (S14 family) 0.0083 0.003 0.0075
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0067 0.0023 0.0079
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0029 0.0007 0.0007
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0067 0.0023 0.0079
Brugia malayi Ferm domain 0.0082 0.003 0.01
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0007 0.0602
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0067 0.0023 0.0058
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.1378
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.1315 0.0546 0.1378
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0014 0.0001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0002
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0029 0.0007 0.0007
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0007 0.0602
Plasmodium falciparum serine repeat antigen 7 0.0067 0.0023 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.012 0.0485
Echinococcus multilocularis protein tyrosine kinase 0.6956 0.2908 0.2908
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Mycobacterium ulcerans hypothetical protein 0.0014 0.0001 0.0338
Schistosoma mansoni protein kinase 0.0029 0.0007 0.0018
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Trypanosoma brucei cAMP binding protein, putative 0.0014 0.0001 0.0018
Giardia lamblia Kinase, NEK 0.0029 0.0007 0.0018
Brugia malayi neurofibromatosis homolog protein 1 0.0082 0.003 0.01
Giardia lamblia Kinase, NEK 0.0029 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0067 0.0023 0.0079
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0002 0.004
Loa Loa (eye worm) MyTH4 domain-containing protein 0.0082 0.003 0.01
Echinococcus multilocularis lamin 0.0028 0.0007 0.0007
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0016 0.0287
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.947 0.396 1
Loa Loa (eye worm) hypothetical protein 0.0297 0.012 0.0406
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0029 0.0007 0.0024
Entamoeba histolytica hypothetical protein 0.0029 0.0007 0.0602
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0067 0.0023 0.0094
Echinococcus granulosus cathepsin L cysteine protease 0.0165 0.0064 0.0064
Brugia malayi SH2 domain containing protein 0.0029 0.0007 0.0024
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Loa Loa (eye worm) TK/ACK protein kinase 0.0029 0.0007 0.0024
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0003 0.0003
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0029 0.0007 0.0007
Echinococcus multilocularis c src tyrosine kinase 0.0029 0.0007 0.0007
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0029 0.0007 0.0018
Echinococcus granulosus FERM domain containing protein 3 0.0082 0.003 0.003
Onchocerca volvulus 0.0082 0.003 0.2471
Loa Loa (eye worm) fibroinase 0.0297 0.012 0.0406
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0002 0.0005
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0002 0.0005
Schistosoma mansoni tyrosine protein kinase 0.0029 0.0007 0.0018
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Loa Loa (eye worm) hypothetical protein 0.0082 0.003 0.01
Schistosoma mansoni protein kinase 0.0029 0.0007 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.1315 0.0546 1
Brugia malayi Cathepsin L-like precursor 0.0297 0.012 0.0406
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.012 0.0485
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1315 0.0546 0.1378
Loa Loa (eye worm) SRC-1 0.0029 0.0007 0.0024
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0014 0.0001 0.0001
Trypanosoma brucei cAMP-specific phosphodiesterase 0.1315 0.0546 1
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0019 0.0003 0.0003
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.2212
Entamoeba histolytica hypothetical protein 0.0029 0.0007 0.0602
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Brugia malayi hypothetical protein 0.0106 0.004 0.0135
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0007 0.0602
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0029 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.012 0.0485
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Entamoeba histolytica cysteine protease, putative 0.0165 0.0064 0.5352
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Brugia malayi Papain family cysteine protease containing protein 0.0297 0.012 0.0406
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0082 0.003 0.003
Echinococcus multilocularis musashi 0.0028 0.0007 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.012 0.2191
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0475 0.0194 0.049
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0002 0.004
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1315 0.0546 0.1378
Brugia malayi Thioredoxin reductase 0.0049 0.0016 0.0053
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0029 0.0007 0.0602
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.5935 0.248 0.248
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0007 0.0602
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Brugia malayi Papain family cysteine protease containing protein 0.0165 0.0064 0.0218
Mycobacterium ulcerans transmembrane transport protein 0.0014 0.0001 0.0338
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.012 0.0485
Echinococcus multilocularis receptor type guanylyl cyclase 0.0029 0.0007 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Giardia lamblia Cathepsin L precursor 0.0067 0.0023 0.0058
Loa Loa (eye worm) hypothetical protein 0.0082 0.003 0.01
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.2212
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0067 0.0023 0.0094
Loa Loa (eye worm) hypothetical protein 0.0106 0.004 0.0135
Echinococcus multilocularis natriuretic peptide receptor 1 0.0029 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0082 0.003 0.01
Schistosoma mansoni protein kinase 0.0029 0.0007 0.0018
Brugia malayi Ferm domain (protein4.1-ezrin-radixin-moesin) family protein 4-like 0.0082 0.003 0.01
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0008 0.002
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0083 0.003 1
Toxoplasma gondii STE kinase 0.0029 0.0007 0.0018
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0003 0.0055
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 2.3894 1 1
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0002 0.004
Echinococcus multilocularis tyrosine protein kinase csk 0.0029 0.0007 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Echinococcus multilocularis Pleckstrin y 0.0082 0.003 0.003
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0019 0.0047
Toxoplasma gondii cathepsin CPC2 0.3635 0.1517 0.3831
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0007 0.0023
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Onchocerca volvulus 0.0297 0.012 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0067 0.0023 0.0079
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0029 0.0007 0.0602
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0007 0.0018
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0029 0.0007 0.0007
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0082 0.003 0.003
Loa Loa (eye worm) TK/ABL protein kinase 0.0029 0.0007 0.0024
Leishmania major cathepsin L-like protease 0.0297 0.012 0.2177
Mycobacterium ulcerans hypothetical protein 0.0014 0.0001 0.0338
Brugia malayi follicle stimulating hormone receptor 0.0241 0.0096 0.0326
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.012 0.0485
Schistosoma mansoni cathepsin S (C01 family) 0.0067 0.0023 0.0058
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0007 0.0029
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0082 0.003 0.003
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Plasmodium falciparum tyrosine kinase-like protein 0.0029 0.0007 0.0018
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.0003 0.001
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0029 0.0007 0.0018
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0003 0.0003
Brugia malayi glutathione reductase 0.0049 0.0016 0.0053
Entamoeba histolytica hypothetical protein 0.0029 0.0007 0.0602
Loa Loa (eye worm) TK/Met protein kinase 0.0029 0.0007 0.0024
Echinococcus granulosus protein tyrosine kinase 0.6956 0.2908 0.2908
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0007 0.0023
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0029 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0007 0.0029
Brugia malayi cathepsin L precursor 0.0067 0.0023 0.0079
Schistosoma mansoni hypothetical protein 0.0082 0.003 0.0075
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1315 0.0546 0.1378
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Entamoeba histolytica hypothetical protein 0.0029 0.0007 0.0602
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0019 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.012 0.0485
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0029 0.0007 0.0024
Loa Loa (eye worm) glutathione reductase 0.0049 0.0016 0.0053
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.003 1
Echinococcus granulosus tyrosine protein kinase pr2 0.0029 0.0007 0.0007
Giardia lamblia Cathepsin B precursor 0.0067 0.0023 0.0058
Echinococcus multilocularis ephrin type A receptor 4 A 0.0029 0.0007 0.0007
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0029 0.0007 0.0007
Brugia malayi Unc-112 related protein. 0.0082 0.003 0.01
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0007 0.0602
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0035 0.0035
Echinococcus granulosus retinal guanylyl cyclase 2 0.0029 0.0007 0.0007
Treponema pallidum cyclic nucleotide binding protein 0.0014 0.0001 0.0338
Plasmodium vivax vivapain-3 0.0165 0.0064 0.0162
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0002 0.0022
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.1315 0.0546 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.0029 0.0007 0.0007
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0029 0.0007 0.0024
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.1315 0.0546 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0007 0.0602
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Echinococcus granulosus intermediate filament protein 0.0028 0.0007 0.0007
Brugia malayi cathepsin B-like cysteine proteinase 0.0475 0.0194 0.0659
Plasmodium falciparum serine repeat antigen 3 0.0067 0.0023 0.0058
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0029 0.0007 0.0007
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1315 0.0546 0.1378
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0003 0.0055
Echinococcus multilocularis tyrosine kinase 0.0029 0.0007 0.0007
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Echinococcus multilocularis cathepsin b 0.0475 0.0194 0.0194
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1315 0.0546 0.1378
Loa Loa (eye worm) TK/RYK protein kinase 0.0029 0.0007 0.0024
Brugia malayi SRC-1 0.0029 0.0007 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.1315 0.0546 0.2212
Trypanosoma cruzi cAMP response protein 1, putative 0.0014 0.0001 0.0018
Echinococcus granulosus cysteine protease 0.0165 0.0064 0.0064
Brugia malayi hypothetical protein 0.0182 0.0071 0.0243
Echinococcus multilocularis tyrosine protein kinase HCK 0.0029 0.0007 0.0007
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1315 0.0546 0.1378
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0029 0.0007 0.0007
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0014 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.6956 0.2908 0.7342
Echinococcus granulosus natriuretic peptide receptor 1 0.0029 0.0007 0.0007
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Giardia lamblia Cathepsin L precursor 0.0067 0.0023 0.0058
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0019 0.0003 0.0967
Echinococcus multilocularis tyrosine protein kinase Srms 0.0029 0.0007 0.0007
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0014 0.0001 0.0003
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0002 0.0005
Plasmodium vivax unspecified product 0.0165 0.0064 0.0162
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.2212
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Plasmodium vivax tyrosine kinase-like protein, putative 0.0029 0.0007 0.0018
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Trypanosoma brucei trypanothione reductase 0.0049 0.0016 0.0287
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.012 0.0485
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Onchocerca volvulus 0.0029 0.0007 0.0602
Loa Loa (eye worm) PDE1B protein 0.1315 0.0546 0.1855
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0067 0.0023 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.012 0.2191
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0001 0.0005
Giardia lamblia Cathepsin B precursor 0.0193 0.0076 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0007 0.0029
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0003 0.0008
Trypanosoma cruzi ribonuclease inhibitor, putative 0.0082 0.003 0.0542
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0029 0.0007 0.0007
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0003 0.0037
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0029 0.0007 0.0007
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0007 0.0024
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0002 0.004
Brugia malayi C-terminal src kinase protein 1 0.0029 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1315 0.0546 0.1378
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0029 0.0007 0.0007
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0003 0.0052
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.462 0.1929 0.1929
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.5935 0.248 0.6262
Echinococcus granulosus patatin phospholipase domain containing protein 0.0014 0.0001 0.0001
Brugia malayi Cathepsin L-like precursor 0.0297 0.012 0.0406
Schistosoma mansoni protein kinase 0.0029 0.0007 0.0018
Entamoeba histolytica ankyrin repeat protein 0.0029 0.0007 0.0602
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0001 0.0003
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0016 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0001 0.0003
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Treponema pallidum catabolite gene activator 0.0014 0.0001 0.0338
Entamoeba histolytica tyrosin kinase, putative 0.0029 0.0007 0.0602
Brugia malayi protein-tyrosine-phosphatase 0.0082 0.003 0.01
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.1378
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0002 0.004
Onchocerca volvulus 0.0029 0.0007 0.0602
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0029 0.0007 0.0024
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0003 0.0003
Leishmania major cathepsin L-like protease 0.0297 0.012 0.2177
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Echinococcus multilocularis tyrosine kinase 0.0029 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.003 0.012
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0021
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0067 0.0023 0.0058
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0001 0.0005
Onchocerca volvulus 0.0067 0.0023 0.1934
Trypanosoma cruzi hypothetical protein, conserved 0.1315 0.0546 1
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0014 0.0001 0.0001
Schistosoma mansoni protein kinase 0.0029 0.0007 0.0018
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0002 0.004
Entamoeba histolytica cysteine protease, putative 0.0067 0.0023 0.1934
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0029 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0067 0.0023 0.0079
Trypanosoma cruzi hypothetical protein, conserved 0.1315 0.0546 1
Mycobacterium leprae Conserved hypothetical protein 0.0014 0.0001 0.0211
Mycobacterium tuberculosis Probable dehydrogenase 0.0112 0.0042 0.8867
Trichomonas vaginalis conserved hypothetical protein 0.1315 0.0546 0.2212
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0029 0.0007 0.0007
Brugia malayi GRP1 binding protein 0.0082 0.003 0.01
Brugia malayi CXXC zinc finger family protein 0.003 0.0008 0.0026
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.132 0.0548 0.1383
Echinococcus multilocularis talin 2 0.0082 0.003 0.003
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Echinococcus granulosus protein 4.1 0.0082 0.003 0.003
Toxoplasma gondii cathepsin CPC1 0.947 0.396 1
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0014 0.0001 0.0001
Loa Loa (eye worm) TK protein kinase 0.0029 0.0007 0.0024
Echinococcus granulosus kinase suppressor of Ras 1 0.0029 0.0007 0.0007
Echinococcus granulosus cathepsin L 0.0067 0.0023 0.0023
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.947 0.396 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0007 0.0024
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Schistosoma mansoni merlin/moesin/ezrin/radixin 0.0082 0.003 0.0075
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0081 0.0029 0.0098
Treponema pallidum NADH oxidase 0.0017 0.0002 0.0735
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0003 0.0003
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0003 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0165 0.0064 0.0259
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0013 0 0.0001
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0002 0.0253
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0002 0.0735
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0112 0.0042 0.8867
Giardia lamblia Cathepsin L precursor 0.0067 0.0023 0.0058
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0003 0.001
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0008 0.0026
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.1315 0.0546 0.1855
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Brugia malayi Cathepsin L-like precursor 0.02 0.0079 0.0267
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.5935 0.248 0.248
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.1315 0.0546 0.0546
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.1315 0.0546 1
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0067 0.0023 0.0094
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0201 0.0079 0.0269
Mycobacterium ulcerans hypothetical protein 0.0014 0.0001 0.0338
Onchocerca volvulus Cathepsin L homolog 0.0297 0.012 1
Plasmodium falciparum phosphodiesterase gamma, putative 0.1315 0.0546 0.1378
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0026 0.0006 0.0021
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0003
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.0001 0.0003
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0029 0.0007 0.0007
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.1315 0.0546 0.1378
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.1315 0.0546 0.1378
Loa Loa (eye worm) hypothetical protein 0.0082 0.003 0.01
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0067 0.0023 0.0058
Echinococcus multilocularis 0.0082 0.003 0.003
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0067 0.0023 0.0058
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0014 0.0001 0.0001
Brugia malayi Cyclic-nucleotide gated cation channel 0.0019 0.0003 0.0011
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0029 0.0007 0.0007
Echinococcus granulosus FERM domain containing protein 5 0.0082 0.003 0.003
Onchocerca volvulus 0.0029 0.0007 0.0602
Entamoeba histolytica cysteine protease, putative 0.0165 0.0064 0.5352
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.1315 0.0546 0.1378
Echinococcus multilocularis transfer RNA-Thr 0.0029 0.0007 0.0007
Trypanosoma cruzi cysteine peptidase, putative 0.0297 0.012 0.2191
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Echinococcus multilocularis activated cdc42 kinase 1 0.0029 0.0007 0.0007
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.0165 0.0064 0.5352
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.1315 0.0546 0.2212
Echinococcus multilocularis FERM domain containing protein 3 0.0082 0.003 0.003
Echinococcus multilocularis FERM central domain 0.0082 0.003 0.003
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0003 0.0008
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0029 0.0007 0.0018
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0007 0.0024
Plasmodium falciparum serine repeat antigen 1 0.0067 0.0023 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.02 0.0079 0.0319
Echinococcus granulosus cathepsin b 0.0475 0.0194 0.0194
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0023 0.0094
Loa Loa (eye worm) hypothetical protein 0.003 0.0008 0.0026
Mycobacterium tuberculosis Probable oxidoreductase 0.0125 0.0047 1
Mycobacterium ulcerans regulatory protein 0.0014 0.0001 0.0338
Onchocerca volvulus 0.0014 0.0001 0.0084
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0007 0.0602
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.1315 0.0546 0.1378
Brugia malayi MyTH4 domain containing protein 0.0082 0.003 0.01
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.012 0.2191
Leishmania major cathepsin L-like protease 0.0297 0.012 0.2177
Schistosoma mansoni lamin 0.0028 0.0007 0.0017
Onchocerca volvulus 0.0029 0.0007 0.0602
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0067 0.0023 0.0094
Plasmodium falciparum tyrosine kinase-like protein 0.0029 0.0007 0.0018
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Echinococcus granulosus tyrosine kinase 0.0029 0.0007 0.0007
Trypanosoma brucei protein kinase, putative 0.0029 0.0007 0.0132
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1315 0.0546 0.1378
Plasmodium falciparum protein kinase, putative 0.0029 0.0007 0.0018
Trypanosoma brucei Flagellum attachment zone protein 20 0.0029 0.0007 0.0132
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Echinococcus granulosus voltage gated potassium channel 0.0026 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0082 0.003 0.0075
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0076 0.0027 0.0109
Schistosoma mansoni lamin 0.0028 0.0007 0.0017
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0007 0.0602
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0067 0.0023 0.0079
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0003 0.0003
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Brugia malayi Cytochrome P450 family protein 0.0019 0.0003 0.001
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Loa Loa (eye worm) TK/EGFR protein kinase 0.0029 0.0007 0.0024
Trypanosoma brucei Pseudokinase, putative 0.0029 0.0007 0.0132
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.1315 0.0546 1
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.5935 0.248 0.248
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.012 0.2191
Schistosoma mansoni Band 4.1-like protein 0.0082 0.003 0.0075
Plasmodium falciparum protein kinase, putative 0.0029 0.0007 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0023 0.0094
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0007 0.0024
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0007 0.0024
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0014 0.0001 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0297 0.012 0.0485
Brugia malayi Ferm domain 0.0082 0.003 0.01
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Echinococcus granulosus tyrosine protein kinase csk 0.0029 0.0007 0.0007
Entamoeba histolytica hypothetical protein 0.0029 0.0007 0.0602
Loa Loa (eye worm) hypothetical protein 0.0082 0.003 0.01
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Loa Loa (eye worm) hypothetical protein 0.0082 0.003 0.01
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Trichomonas vaginalis protein kinase atn1, putative 0.0029 0.0007 0.0029
Schistosoma mansoni protein kinase 0.0029 0.0007 0.0018
Brugia malayi cathepsin L-like cysteine proteinase 0.0067 0.0023 0.0079
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0014 0.0001 0.0018
Brugia malayi FERM domain 0.0082 0.003 0.01
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.5935 0.248 0.8429
Loa Loa (eye worm) hypothetical protein 0.0098 0.0036 0.0122
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0007 0.0602
Giardia lamblia Cathepsin L precursor 0.0067 0.0023 0.0058
Echinococcus granulosus tyrosine kinase 0.0029 0.0007 0.0007
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0003 0.0003
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0297 0.012 0.0302
Brugia malayi hypothetical protein 0.002 0.0003 0.0011
Trypanosoma brucei Flagellar Member 6 0.0014 0.0001 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.012 0.2191
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0016 0.004
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0007 0.0024
Leishmania major protein kinase, putative 0.0029 0.0007 0.0114
Brugia malayi Probable ClpP-like protease 0.0083 0.003 0.0101
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0016 0.0053
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Giardia lamblia Cathepsin L-like protease 0.0067 0.0023 0.0058
Leishmania major cathepsin L-like protease 0.0297 0.012 0.2177
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Plasmodium vivax glutathione reductase, putative 0.0049 0.0016 0.004
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.1315 0.0546 0.0546
Echinococcus multilocularis SPRY domain containing protein 0.0082 0.003 0.003
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Brugia malayi Cathepsin L-like precursor 0.0297 0.012 0.0406
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0067 0.0023 0.0058
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0067 0.0023 0.0058
Loa Loa (eye worm) hypothetical protein 0.0067 0.0023 0.0079
Treponema pallidum catabolite gene activator (Crp) 0.0014 0.0001 0.0338
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0029 0.0007 0.0602
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.2212
Brugia malayi Papain family cysteine protease containing protein 0.0067 0.0023 0.0079
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.003 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.012 0.2191
Entamoeba histolytica hypothetical protein 0.0029 0.0007 0.0602
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0029 0.0007 0.0024
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0026 0.0006 0.0006
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0029 0.0007 0.0602
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Giardia lamblia Cathepsin B precursor 0.0193 0.0076 0.0192
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0007 0.0024
Onchocerca volvulus Cathepsin L homolog 0.0297 0.012 1
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0029 0.0007 0.0007
Toxoplasma gondii thioredoxin reductase 0.0049 0.0016 0.004
Brugia malayi Papain family cysteine protease containing protein 0.0067 0.0023 0.0079
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Echinococcus granulosus tyrosine protein kinase csk 0.0029 0.0007 0.0007
Schistosoma mansoni cathepsin F (C01 family) 0.02 0.0079 0.0199
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Echinococcus multilocularis peptidase Clp (S14 family) 0.0054 0.0018 0.0018
Leishmania major cathepsin L-like protease 0.0297 0.012 0.2177
Echinococcus multilocularis cathepsin L 0.0165 0.0064 0.0064
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0029 0.0007 0.0029
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0029 0.0007 0.0007
Plasmodium falciparum serine repeat antigen 8 0.0067 0.0023 0.0058
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0029 0.0007 0.0007
Echinococcus multilocularis protein tyrosine phosphatase, non receptor type 0.0082 0.003 0.003
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0007 0.0602
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0007 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.012 0.0485
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0007 0.0602
Schistosoma mansoni hypothetical protein 0.0014 0.0001 0.0002
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Brugia malayi Cathepsin L-like precursor 0.0297 0.012 0.0406
Entamoeba histolytica cysteine protease, putative 0.0067 0.0023 0.1934
Entamoeba histolytica cysteine proteinase, putative 0.0165 0.0064 0.5352
Giardia lamblia Cysteine protease 0.0067 0.0023 0.0058
Trypanosoma cruzi hypothetical protein 0.0082 0.003 0.0542
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.012 0.2191
Loa Loa (eye worm) TK/DDR protein kinase 0.0029 0.0007 0.0024
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0029 0.0007 0.0007
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0003 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.003 0.012
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.1315 0.0546 0.0546
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.1315 0.0546 0.0546
Brugia malayi Tyrosine-protein kinase PR2 0.0029 0.0007 0.0024
Giardia lamblia Dipeptidyl-peptidase I precursor 0.3635 0.1517 0.3831
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0007 0.0602
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0029 0.0007 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0067 0.0023 0.0094
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0029 0.0007 0.0007
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Schistosoma mansoni hypothetical protein 0.0082 0.003 0.0075
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Entamoeba histolytica cysteine protease, putative 0.0165 0.0064 0.5352
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0007 0.0602
Echinococcus granulosus raf serine:threonine protein kinase 0.0029 0.0007 0.0007
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0029 0.0007 0.0024
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0007 0.0024
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.1315 0.0546 0.1378
Brugia malayi hypothetical protein 0.0029 0.0007 0.0024
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0007 0.0602
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0083 0.003 0.6248
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.003 0.0075
Echinococcus multilocularis FL cytokine receptor 0.0029 0.0007 0.0007
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0112 0.0042 0.8891
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0083 0.003 0.0075
Onchocerca volvulus Cathepsin L homolog 0.0067 0.0023 0.1934
Loa Loa (eye worm) TK protein kinase 0.0029 0.0007 0.0024
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0029 0.0007 0.0007
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.1315 0.0546 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0002 0.004
Echinococcus granulosus tyrosine protein kinase Fyn 0.0029 0.0007 0.0007
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0026 0.0006 0.0006
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0067 0.0023 0.0058
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0082 0.003 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0193 0.0076 0.0308
Onchocerca volvulus 0.02 0.0079 0.6581
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.012 0.0485
Echinococcus granulosus protein kinase 0.0029 0.0007 0.0007
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0083 0.003 0.003
Trypanosoma cruzi cAMP response protein 1 0.0014 0.0001 0.0018
Loa Loa (eye worm) TK protein kinase 0.0029 0.0007 0.0024
Plasmodium falciparum phosphodiesterase delta, putative 0.1315 0.0546 0.1378
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.2212
Onchocerca volvulus 0.0297 0.012 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0016 0.3163
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.003 1
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0014 0.0001 0.0004
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.1315 0.0546 1
Schistosoma mansoni cpg binding protein 0.003 0.0008 0.0019
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0014 0.0001 0.0001
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0007 0.0024
Leishmania major protein kinase, putative 0.0029 0.0007 0.0114
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0019 0.0003 0.0003
Echinococcus granulosus SPRY domain containing protein 0.0082 0.003 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.012 0.0485
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0165 0.0064 0.1173
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.003 1
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.1315 0.0546 0.0546
Echinococcus granulosus protein tyrosine phosphatase non receptor type 0.0082 0.003 0.003
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0003 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.012 0.2191
Entamoeba histolytica hypothetical protein 0.0029 0.0007 0.0602
Brugia malayi GH28553p 0.0082 0.003 0.01
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0007 0.0602
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0193 0.0076 0.0192
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0029 0.0007 0.0024
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0007 0.0024
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0017 0.0002 0.0005
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0067 0.0023 0.1934
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0029 0.0007 0.0018
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0002 0.0002
Echinococcus multilocularis Ezrin radixin moesin ERM 0.0082 0.003 0.003
Trichomonas vaginalis protein tyrosine kinase, putative 0.0029 0.0007 0.0029
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Echinococcus granulosus tyrosine protein kinase ABL1 0.0029 0.0007 0.0007
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Plasmodium vivax protein kinase, putative 0.0029 0.0007 0.0018
Onchocerca volvulus Cathepsin F homolog 0.0297 0.012 1
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0014 0.0001 0.0003
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Echinococcus granulosus integrin linked protein kinase 0.0029 0.0007 0.0007
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0002 0.0735
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1315 0.0546 0.1378
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0054 0.0018 0.3598
Giardia lamblia Cathepsin B precursor 0.0067 0.0023 0.0058
Schistosoma mansoni protein kinase 0.0029 0.0007 0.0018
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0029 0.0007 0.0007
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0297 0.012 0.012
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0016 0.0016
Toxoplasma gondii cathepsin CPL 0.0297 0.012 0.0302
Onchocerca volvulus 0.0297 0.012 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0003 0.0013
Echinococcus granulosus c src tyrosine kinase 0.0029 0.0007 0.0007
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0002 0.0735
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Loa Loa (eye worm) hypothetical protein 0.0013 0 0.0002
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0007 0.0602
Trypanosoma brucei protein kinase A regulatory subunit 0.0014 0.0001 0.0018
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0002 0.004
Trypanosoma brucei hypothetical protein, conserved 0.1315 0.0546 1
Echinococcus granulosus FERM central domain 0.0082 0.003 0.003
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0201 0.0079 0.6615
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.0007 0.0018
Onchocerca volvulus 0.0029 0.0007 0.0602
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Echinococcus granulosus merlin:moesin:ezrin:radixin 0.0082 0.003 0.003
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0007 0.0602
Onchocerca volvulus Tyrosine kinase homolog 0.0029 0.0007 0.0602
Echinococcus multilocularis tyrosine protein kinase Blk 0.0029 0.0007 0.0007
Echinococcus multilocularis talin 0.0082 0.003 0.003
Schistosoma mansoni merlin/moesin/ezrin/radixin 0.0082 0.003 0.0075
Echinococcus multilocularis activin receptor type 0.0029 0.0007 0.0007
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Giardia lamblia Cathepsin B precursor 0.0193 0.0076 0.0192
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Schistosoma mansoni hypothetical protein 0.0082 0.003 0.0075
Entamoeba histolytica cysteine protease, putative 0.0165 0.0064 0.5352
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.2212
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0029 0.0007 0.0024
Trichomonas vaginalis TK family protein kinase 0.0029 0.0007 0.0029
Trypanosoma cruzi ribonuclease inhibitor, putative 0.0082 0.003 0.0542
Plasmodium vivax serine-repeat antigen (SERA) 0.0067 0.0023 0.0058
Trypanosoma cruzi cysteine proteinase, putative 0.0165 0.0064 0.1173
Brugia malayi protein-tyrosine kinase 0.0029 0.0007 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0023 0.0094
Trypanosoma brucei cAMP-specific phosphodiesterase 0.1315 0.0546 1
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Schistosoma mansoni protein kinase 0.0029 0.0007 0.0018
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0029 0.0007 0.0029
Trypanosoma cruzi cysteine peptidase, putative 0.0165 0.0064 0.1173
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0165 0.0064 0.0259
Loa Loa (eye worm) ctsf protein 0.0297 0.012 0.0406
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0003 0.0008
Trypanosoma cruzi cysteine peptidase, putative 0.0297 0.012 0.2191
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0029 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0023 0.0094
Echinococcus multilocularis tyrosine protein kinase pr2 0.0029 0.0007 0.0007
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0014 0.0001 0.0003
Echinococcus granulosus epidermal growth factor receptor 0.0029 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0023 0.0094
Trypanosoma cruzi cysteine peptidase, putative 0.0297 0.012 0.2191
Entamoeba histolytica tyrosin kinase, putative 0.0029 0.0007 0.0602
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.1378
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.5935 0.248 0.6262
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0007 0.0602
Giardia lamblia Cysteine protease 0.0067 0.0023 0.0058
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0029 0.0007 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0297 0.012 0.0485
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0007 0.0602
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Loa Loa (eye worm) serine/threonine protein kinase 0.0029 0.0007 0.0024
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0112 0.0042 0.8867
Entamoeba histolytica cysteine protease, putative 0.0165 0.0064 0.5352
Brugia malayi cathepsin L-like precursor 0.02 0.0079 0.0267
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Echinococcus multilocularis heat shock protein 70 0.0029 0.0007 0.0007
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0007 0.0602
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0002 0.0735
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0035 0.0089
Entamoeba histolytica cysteine protease, putative 0.0067 0.0023 0.1934
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0029 0.0007 0.0602
Echinococcus granulosus insulin receptor 0.0029 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Entamoeba histolytica receptor protein kinase, putative 0.0029 0.0007 0.0602
Giardia lamblia Cathepsin B precursor 0.0067 0.0023 0.0058
Trypanosoma cruzi cysteine peptidase, putative 0.0297 0.012 0.2191
Echinococcus granulosus cathepsin L cysteine proteinase 0.0297 0.012 0.012
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Onchocerca volvulus 4.1 G protein, putative homolog 0.0082 0.003 0.2471
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0008 0.0142
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0067 0.0023 0.0058
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0007 0.0602
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0028 0.0007 0.0018
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Schistosoma mansoni protein kinase 0.0029 0.0007 0.0018
Onchocerca volvulus 0.0082 0.003 0.2471
Entamoeba histolytica cysteine surface protein, putative 0.0029 0.0007 0.0602
Schistosoma mansoni voltage-gated potassium channel 0.0088 0.0032 0.0081
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0007 0.0602
Loa Loa (eye worm) hypothetical protein 0.0098 0.0036 0.0122
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0029 0.0007 0.0007
Brugia malayi hypothetical protein 0.0029 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0082 0.003 0.01
Plasmodium vivax vivapain-2 0.0297 0.012 0.0302
Loa Loa (eye worm) hypothetical protein 0.0082 0.003 0.01
Giardia lamblia Encystation-specific protease 0.3635 0.1517 0.3831
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.1315 0.0546 1
Entamoeba histolytica cysteine protease, putative 0.0165 0.0064 0.5352
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Brugia malayi hypothetical protein 0.0082 0.003 0.01
Onchocerca volvulus 0.003 0.0008 0.0629
Toxoplasma gondii cathepsin B 0.0193 0.0076 0.0192
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0297 0.012 0.0302
Echinococcus granulosus cathepsin l cysteine peptidase 0.0297 0.012 0.012
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0112 0.0042 0.8867
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0014 0.0001 0.0003
Onchocerca volvulus 0.0014 0.0001 0.0084
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Trypanosoma cruzi protein kinase A regulatory subunit 0.0014 0.0001 0.0018
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0008 0.0142
Schistosoma mansoni cpg binding protein 0.0032 0.0008 0.0021
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1315 0.0546 0.1378
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0082 0.003 0.0075
Brugia malayi Cathepsin L-like precursor 0.0098 0.0036 0.0122
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.1315 0.0546 1
Schistosoma mansoni intermediate filament proteins 0.0028 0.0007 0.0017
Echinococcus granulosus lamin dm0 0.0028 0.0007 0.0007
Brugia malayi N-terminal motif family protein 0.0201 0.0079 0.0269
Loa Loa (eye worm) hypothetical protein 0.02 0.0079 0.0267
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0007 0.0024
Entamoeba histolytica cysteine protease, putative 0.0165 0.0064 0.5352
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0098 0.0036 0.0122
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0067 0.0023 0.0058
Loa Loa (eye worm) TK protein kinase 0.0029 0.0007 0.0024
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.1315 0.0546 0.0546
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0003 0.0003
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.594 0.2482 0.6267
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Leishmania major hypothetical protein, conserved 0.1315 0.0546 1
Echinococcus multilocularis protein kinase 0.0029 0.0007 0.0007
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.5935 0.248 0.248
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.2212
Onchocerca volvulus 0.0297 0.012 1
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0029 0.0007 0.0132
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0014 0.0001 0.0003
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Plasmodium falciparum cysteine proteinase falcipain 1 0.0165 0.0064 0.0162
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0029 0.0007 0.0018
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0029 0.0007 0.0007
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0007 0.0023
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0003 0.001
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0014 0.0001 0.0001
Brugia malayi Egg laying defective protein 4 0.0014 0.0001 0.0003
Echinococcus multilocularis tyrosine protein kinase csk 0.0029 0.0007 0.0007
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.0003 0.0055
Echinococcus multilocularis dnaJ subfamily B 0.0425 0.0173 0.0173
Brugia malayi intermediate filament protein 0.0028 0.0007 0.0023
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0081 0.0029 0.0029
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0082 0.003 0.003
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0475 0.0194 0.3554
Plasmodium falciparum cGMP-specific phosphodiesterase 0.1315 0.0546 0.1378
Plasmodium falciparum cGMP-specific phosphodiesterase 0.1315 0.0546 0.1378
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.0035 0.012
Onchocerca volvulus 0.0029 0.0007 0.0602
Trypanosoma brucei cysteine peptidase C (CPC) 0.0193 0.0076 0.1392
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.012 0.0485
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.02 0.0079 0.0319
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0029 0.0007 0.0132
Schistosoma mansoni cathepsin B (C01 family) 0.0067 0.0023 0.0058
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0029 0.0007 0.0007
Giardia lamblia Hypothetical protein 0.0067 0.0023 0.0058
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.1315 0.0546 0.1378
Plasmodium vivax phosphodiesterase gamma, putative 0.1315 0.0546 0.1378
Giardia lamblia Dipeptidyl-peptidase I precursor 0.947 0.396 1
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0007 0.0024
Echinococcus granulosus retinal guanylyl cyclase 2 0.0029 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0007 0.0029
Echinococcus granulosus Ezrin radixin moesin ERM 0.0082 0.003 0.003
Loa Loa (eye worm) TK protein kinase 0.0029 0.0007 0.0024
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0029 0.0007 0.0018
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0014 0.0001 0.0018
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.1315 0.0546 0.2212
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0035 0.0035
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0029 0.0007 0.0024
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0035 0.0089
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0002 0.0022
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.462 0.1929 0.6557
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.0003 0.0008
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0297 0.012 0.0406
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.02 0.0079 0.1442
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0007 0.0602
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0029 0.0007 0.0007
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0007 0.0602
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0067 0.0023 0.0058
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0003 0.0008
Entamoeba histolytica serine/threonine kinase, putative 0.0029 0.0007 0.0602
Leishmania major hypothetical protein, conserved 0.1315 0.0546 1
Echinococcus granulosus tyrosine protein kinase 0.0029 0.0007 0.0007
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0003 0.0055
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1315 0.0546 0.1378
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0014 0.0001 0.0338
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.012 0.2191
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0067 0.0023 0.0058
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0003 0.0003
Plasmodium falciparum glutathione reductase 0.0049 0.0016 0.004
Plasmodium vivax vivapain-1 0.0165 0.0064 0.0162
Brugia malayi Receptor family ligand binding region containing protein 0.0029 0.0007 0.0024
Toxoplasma gondii preprocathepsin c precursor, putative 0.947 0.396 1
Schistosoma mansoni cathepsin F (C01 family) 0.0297 0.012 0.0302
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Schistosoma mansoni protein kinase 0.0029 0.0007 0.0018
Entamoeba histolytica protein kinase, putative 0.0029 0.0007 0.0602
Brugia malayi Tyrosine-protein kinase abl-1 0.0029 0.0007 0.0024
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0014 0.0001 0.0003
Echinococcus multilocularis voltage gated potassium channel 0.0026 0.0006 0.0006
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0007 0.0602
Plasmodium vivax vivapain-2 0.0297 0.012 0.0302
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0003 0.0008
Echinococcus granulosus fibroblast growth factor receptor 4 0.0029 0.0007 0.0007
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0029 0.0007 0.0007
Echinococcus multilocularis FERM domain containing protein 5 0.0082 0.003 0.003
Trichomonas vaginalis conserved hypothetical protein 0.1315 0.0546 0.2212
Loa Loa (eye worm) TK/FER protein kinase 0.0029 0.0007 0.0024
Leishmania major hypothetical protein, conserved 0.0029 0.0007 0.0114
Toxoplasma gondii protein kinase domain-containing protein 0.0029 0.0007 0.0018
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0081 0.0029 0.0029
Echinococcus granulosus activated cdc42 kinase 1 0.0029 0.0007 0.0007
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0003 0.0011
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0013 0 0.0001
Echinococcus multilocularis expressed conserved protein 0.0014 0.0001 0.0001
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0007 0.0602
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.947 0.396 1
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0029 0.0007 0.0007
Entamoeba histolytica protein kinase domain containing protein 0.0029 0.0007 0.0602
Echinococcus multilocularis cathepsin L cysteine protease 0.0297 0.012 0.012
Onchocerca volvulus Putative 4.1 G protein 0.0082 0.003 0.2471
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.003 0.012
Plasmodium falciparum cGMP-dependent protein kinase 0.0014 0.0001 0.0003
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0098 0.0036 0.0122
Schistosoma mansoni hypothetical protein 0.0082 0.003 0.0075
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0014 0.0001 0.0003
Trypanosoma cruzi cruzipain precursor, putative 0.0098 0.0036 0.0658
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0008 0.002
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0076 0.0027 0.0109
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0475 0.0194 0.049
Onchocerca volvulus 0.0082 0.003 0.2471
Loa Loa (eye worm) hypothetical protein 0.1315 0.0546 0.1855
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Echinococcus multilocularis myosin viia 0.0082 0.003 0.003
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0029 0.0007 0.0029
Trichomonas vaginalis STE family protein kinase 0.0029 0.0007 0.0029
Trypanosoma brucei cAMP response protein 1, putative 0.0014 0.0001 0.0018
Treponema pallidum cyclic nucleotide binding protein 0.0014 0.0001 0.0338
Echinococcus granulosus H17g protein tegumental antigen 0.0082 0.003 0.003
Plasmodium vivax unspecified product 0.0067 0.0023 0.0058
Loa Loa (eye worm) cysteine protease 0.0297 0.012 0.0406
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0029 0.0007 0.0602
Loa Loa (eye worm) cathepsin B 0.0193 0.0076 0.0258
Plasmodium falciparum protein kinase, putative 0.0029 0.0007 0.0018
Schistosoma mansoni hypothetical protein 0.0082 0.003 0.0075
Toxoplasma gondii hypothetical protein 0.0028 0.0007 0.0018
Echinococcus multilocularis raf serine:threonine protein kinase 0.0029 0.0007 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Brugia malayi ephrin receptor 1 precursor 0.0029 0.0007 0.0024
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0014 0.0001 0.0003
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0029 0.0007 0.0007
Leishmania major cathepsin L-like protease 0.0297 0.012 0.2177
Trypanosoma cruzi cysteine peptidase, putative 0.0098 0.0036 0.0658
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1315 0.0546 0.1378
Entamoeba histolytica hypothetical protein 0.0029 0.0007 0.0602
Loa Loa (eye worm) hypothetical protein 0.0028 0.0007 0.0022
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0029 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.5902 0.2466 1
Onchocerca volvulus 0.0297 0.012 1
Entamoeba histolytica cysteine proteinase, putative 0.0165 0.0064 0.5352
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0125 0.0047 1
Schistosoma mansoni serine/threonine RGC 0.0029 0.0007 0.0018
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1315 0.0546 0.1378
Plasmodium falciparum thioredoxin reductase 0.0017 0.0002 0.0005
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1315 0.0546 0.1378
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0475 0.0194 0.049
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Loa Loa (eye worm) hypothetical protein 0.0067 0.0023 0.0079
Echinococcus multilocularis cathepsin L cysteine protease 0.0297 0.012 0.012
Giardia lamblia hypothetical protein 0.1315 0.0546 0.1378
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Trypanosoma cruzi major cysteine proteinase, putative 0.0067 0.0023 0.0424
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0067 0.0023 0.0079
Trypanosoma cruzi cysteine protease, putative 0.0165 0.0064 0.1173
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Giardia lamblia Protein 21.1 0.0029 0.0007 0.0018
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Schistosoma mansoni voltage-gated potassium channel 0.0026 0.0006 0.0015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0297 0.012 0.0485
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0002 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0297 0.012 0.2191
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Plasmodium falciparum serine repeat antigen 6 0.0067 0.0023 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0067 0.0023 0.0094
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Echinococcus multilocularis cathepsin L 0.0067 0.0023 0.0023
Echinococcus multilocularis H17g protein, tegumental antigen 0.0082 0.003 0.003
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0014 0.0001 0.0003
Echinococcus granulosus cathepsin l1 0.02 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0067 0.0023 0.0078
Brugia malayi Cathepsin L-like cysteine proteinase 0.02 0.0079 0.0267
Onchocerca volvulus 0.0028 0.0007 0.0568
Entamoeba histolytica tyrosine kinase, putative 0.0029 0.0007 0.0602
Trypanosoma cruzi protein kinase, putative 0.0029 0.0007 0.0132
Echinococcus multilocularis radixin 0.0082 0.003 0.003
Echinococcus multilocularis FERM domain containing protein 5 0.0082 0.003 0.003
Trypanosoma cruzi major cysteine proteinase, putative 0.0067 0.0023 0.0424
Schistosoma mansoni protein kinase 0.0029 0.0007 0.0018
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0029 0.0007 0.0024
Echinococcus multilocularis epidermal growth factor receptor 0.0029 0.0007 0.0007
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.1315 0.0546 0.0546
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.0035 0.012
Brugia malayi Cathepsin L-like precursor 0.0297 0.012 0.0406
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0014 0.0001 0.0003
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0014 0.0001 0.0003
Schistosoma mansoni voltage-gated potassium channel 0.0026 0.0006 0.0015
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0002 0.0007
Echinococcus granulosus talin 2 0.0082 0.003 0.003
Echinococcus multilocularis kinase suppressor of Ras 1 0.0029 0.0007 0.0007
Echinococcus granulosus epidermal growth factor receptor 0.0029 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0067 0.0023 0.0094
Entamoeba histolytica cysteine proteinase, putative 0.0297 0.012 1
Onchocerca volvulus 0.0029 0.0007 0.0602
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0003 0.0011
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Entamoeba histolytica cysteine protease, putative 0.0165 0.0064 0.5352
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0001 0.0004
Loa Loa (eye worm) moesin 0.0082 0.003 0.01
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0007 0.0024
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Schistosoma mansoni hypothetical protein 0.0082 0.003 0.0075
Loa Loa (eye worm) TK/INSR protein kinase 0.0029 0.0007 0.0024
Leishmania major cytochrome p450-like protein 0.0019 0.0003 0.0034
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0029 0.0007 0.0018
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Brugia malayi Protein kinase domain containing protein 0.0029 0.0007 0.0024
Mycobacterium ulcerans transcriptional regulatory protein 0.0014 0.0001 0.0338
Plasmodium vivax unspecified product 0.0098 0.0036 0.0091
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0029 0.0007 0.0029
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0297 0.012 0.012
Giardia lamblia Dipeptidyl-peptidase I precursor 0.3635 0.1517 0.3831
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0014 0.0001 0.0004
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0067 0.0023 0.0094
Schistosoma mansoni hypothetical protein 0.0082 0.003 0.0075
Entamoeba histolytica cysteine protease, putative 0.0165 0.0064 0.5352
Entamoeba histolytica ankyrin repeat protein 0.0029 0.0007 0.0602
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0014 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0082 0.003 0.0075
Echinococcus granulosus cpg binding protein 0.0032 0.0008 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Entamoeba histolytica cysteine proteinase, putative 0.0297 0.012 1
Echinococcus granulosus tyrosine protein kinase Blk 0.0029 0.0007 0.0007
Loa Loa (eye worm) TK/EPH protein kinase 0.0029 0.0007 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0007 0.0029
Loa Loa (eye worm) neurofibromin 2 isoform 8 0.0082 0.003 0.01
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.1315 0.0546 0.2212
Echinococcus multilocularis integrin linked protein kinase 0.0029 0.0007 0.0007
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0029 0.0007 0.0007
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0029 0.0007 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Entamoeba histolytica cysteine protease, putative 0.0067 0.0023 0.1934
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0014 0.0001 0.0003
Echinococcus granulosus tyrosine protein kinase Lyn 0.0029 0.0007 0.0007
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0002 0.0009
Schistosoma mansoni tyrosine kinase 0.0029 0.0007 0.0018
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0029 0.0007 0.0602
Echinococcus multilocularis epidermal growth factor receptor 0.0029 0.0007 0.0007
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0007 0.0024
Trypanosoma cruzi cysteine proteinase, putative 0.0165 0.0064 0.1173
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0002 0.0005
Entamoeba histolytica tyrosin kinase, putative 0.0029 0.0007 0.0602
Trichomonas vaginalis TKL family protein kinase 0.0029 0.0007 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0067 0.0023 0.0094
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0014 0.0001 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0001 0.0003
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.462 0.1929 0.1929
Loa Loa (eye worm) hypothetical protein 0.0475 0.0194 0.0659
Echinococcus granulosus FERM central domain 0.0082 0.003 0.003
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.1315 0.0546 0.2212
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0193 0.0076 0.1392
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0007 0.0029
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0035 0.0035
Echinococcus multilocularis SPRY domain containing protein 0.0082 0.003 0.003
Mycobacterium tuberculosis Probable reductase 0.0112 0.0042 0.8867

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -5 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.818 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.814 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.789 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.775 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.728 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.63 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.481 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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