Detailed information for compound 178921

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 330.484 | Formula: C20H26O2S
  • H donors: 1 H acceptors: 2 LogP: 5.95 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)CCCCCCc1sccc1CCCc1ccccc1
  • InChi: 1S/C20H26O2S/c21-20(22)14-7-2-1-6-13-19-18(15-16-23-19)12-8-11-17-9-4-3-5-10-17/h3-5,9-10,15-16H,1-2,6-8,11-14H2,(H,21,22)
  • InChiKey: WSDYSQYMVNCBGT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens leukotriene B4 receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis tumor protein p63 0.0342 0.0503 0.0502
Entamoeba histolytica hypothetical protein 0.0405 0.0604 0.06
Entamoeba histolytica protein kinase, putative 0.0066 0.0061 0.0057
Schistosoma mansoni amine oxidase 0.0164 0.0218 0.0217
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0017 0.0013
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0022 0.0021
Echinococcus granulosus Nuclear hormone receptor HR96 0.0242 0.0343 0.0342
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0081 0.0085 0.0113
Echinococcus granulosus nuclear receptor nhr 48 0.0242 0.0343 0.0342
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0405 0.0604 0.06
Mycobacterium tuberculosis Conserved protein 0.0037 0.0016 0.0022
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0405 0.0604 0.06
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0061 0.0057
Loa Loa (eye worm) hypothetical protein 0.0477 0.0719 0.0719
Treponema pallidum fructose-bisphosphate aldolase 0.0291 0.0421 0.5839
Entamoeba histolytica protein kinase, putative 0.0066 0.0061 0.0057
Brugia malayi latrophilin 2 splice variant baaae 0.0172 0.0231 0.023
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.6277 1 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0016 0.0022
Loa Loa (eye worm) phosphatidylinositol kinase 0.0405 0.0604 0.0604
Onchocerca volvulus 0.0512 0.0776 0.4552
Loa Loa (eye worm) hypothetical protein 0.0242 0.0343 0.0343
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0081 0.0085 0.0085
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0305 0.0443 0.0443
Brugia malayi glutaminase DH11.1 0.028 0.0405 0.0404
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0405 0.0604 0.0603
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0017 0.0013
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0061 0.0053 0.0052
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0022 0.0021
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0242 0.0343 0.2008
Echinococcus multilocularis sterol regulatory element binding protein 0.0129 0.0162 0.0161
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0512 0.0776 0.0776
Brugia malayi hypothetical protein 0.003 0.0004 0.0003
Brugia malayi nuclear hormone receptor family member odr-7 0.0242 0.0343 0.0342
Echinococcus multilocularis rac serine:threonine kinase 0.0045 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0164 0.0218 0.0218
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0016 0.0015
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.005 0.0165
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.2968 0.4706 0.4705
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0016 0.0042
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0405 0.0604 0.0602
Echinococcus granulosus snurportin 1 0.0306 0.0446 0.0445
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0271 0.0389 0.0388
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.0072 0.1127
Plasmodium vivax hypothetical protein, conserved 0.0164 0.0218 0.3585
Loa Loa (eye worm) hypothetical protein 0.0052 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0242 0.0343 0.0343
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0001 0.0001
Brugia malayi Pax transcription activation domain interacting protein 0.003 0.0004 0.0003
Onchocerca volvulus CoRest homolog 0.1092 0.1703 1
Echinococcus granulosus GPCR family 2 0.0079 0.0083 0.0082
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.2105 0.3324 0.3324
Trichomonas vaginalis PIKK family atypical protein kinase 0.6277 1 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0001 0.0001
Schistosoma mansoni coup transcription factor 0.0512 0.0776 0.0775
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0038 0.0108
Brugia malayi ELM2 domain containing protein 0.0031 0.0006 0.0005
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0016 0.0012
Chlamydia trachomatis protoporphyrinogen oxidase 0.0164 0.0218 1
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.2607 0.4128 0.4127
Plasmodium falciparum acyl-CoA synthetase 0.0054 0.0042 0.0672
Loa Loa (eye worm) steroid hormone receptor 0.0512 0.0776 0.0776
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0059 0.005 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.4075 0.6476 0.6475
Toxoplasma gondii hypothetical protein 0.0081 0.0085 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.3384 0.5371 0.5369
Loa Loa (eye worm) hypothetical protein 0.0037 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0324 0.0474 0.0474
Plasmodium vivax amine transporter, putative 0.0081 0.0085 0.1389
Plasmodium vivax replication factor C subunit 1, putative 0.003 0.0004 0.0034
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0405 0.0604 0.0603
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0405 0.0604 0.06
Schistosoma mansoni nuclear hormone receptor 0.0242 0.0343 0.0342
Brugia malayi hypothetical protein 0.0155 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.1092 0.1703 0.1703
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0421 0.0418
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0119 0.0146 0.0145
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0061 0.0057
Loa Loa (eye worm) hypothetical protein 0.1323 0.2073 0.2073
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0164 0.0218 0.3585
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0016 0.0022
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.003 0.0004 0.00000022677
Loa Loa (eye worm) beta-lactamase 0.0037 0.0016 0.0016
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0405 0.0604 0.0603
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0181 0.0246 0.0245
Schistosoma mansoni hypothetical protein 0.0172 0.0231 0.023
Loa Loa (eye worm) hypothetical protein 0.0164 0.0218 0.0218
Trichomonas vaginalis esterase, putative 0.0037 0.0016 0.0012
Echinococcus multilocularis rest corepressor (corest) protein 0.0031 0.0006 0.0005
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.6277 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0129 0.0162 0.0158
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0405 0.0604 0.06
Loa Loa (eye worm) hypothetical protein 0.0271 0.0389 0.0389
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0291 0.0421 0.0418
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0017 0.0013
Onchocerca volvulus 0.0041 0.0022 0.0122
Schistosoma mansoni hypothetical protein 0.0405 0.0604 0.0603
Loa Loa (eye worm) hypothetical protein 0.0127 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0181 0.0245 0.0245
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0251 0.0358 0.0357
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0054 0.0042 0.0127
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0512 0.0776 0.0775
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.003 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0081 0.0085 0.0085
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0405 0.0604 0.0603
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0405 0.0604 0.0811
Onchocerca volvulus Huntingtin homolog 0.0127 0.016 0.0934
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0061 0.0053 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.4669 0.7426 0.7425
Schistosoma mansoni nuclear receptor 0.0242 0.0343 0.0342
Brugia malayi Protein kinase domain containing protein 0.0066 0.0061 0.0061
Brugia malayi DKFZp564C0469 protein 0.003 0.0004 0.0003
Schistosoma mansoni topbp1 0.003 0.0004 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.1187 0.1856 0.1852
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0054 0.0042 0.0137
Schistosoma mansoni DNA ligase IV 0.003 0.0004 0.0003
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0918 0.1425 0.1424
Mycobacterium ulcerans lipase LipD 0.0037 0.0016 0.0042
Echinococcus granulosus Niemann Pick C1 protein 0.03 0.0436 0.0435
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0405 0.0604 0.06
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0405 0.0604 0.0603
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0477 0.0719 0.0718
Loa Loa (eye worm) phosphatidylinositol 3 0.6277 1 1
Onchocerca volvulus Bile acid receptor homolog 0.0512 0.0776 0.4552
Loa Loa (eye worm) hypothetical protein 0.0172 0.0231 0.0231
Schistosoma mansoni nuclear receptor 0.0242 0.0343 0.0342
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0405 0.0604 0.0603
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0016 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.3751 0.5958 0.5956
Loa Loa (eye worm) hypothetical protein 0.0271 0.0389 0.0389
Mycobacterium ulcerans beta-lactamase 0.0037 0.0016 0.0042
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.1187 0.1856 0.1852
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.03 0.0436 0.0432
Loa Loa (eye worm) hypothetical protein 0.0271 0.0389 0.0389
Schistosoma mansoni steroid hormone receptor ad4bp 0.0512 0.0776 0.0775
Schistosoma mansoni loxhd1 0.0041 0.0022 0.0021
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0119 0.0146 0.0145
Brugia malayi hypothetical protein 0.0081 0.0085 0.0085
Schistosoma mansoni sodium/chloride dependent transporter 0.0081 0.0085 0.0085
Entamoeba histolytica hypothetical protein 0.0405 0.0604 0.06
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0512 0.0776 0.4552
Trichomonas vaginalis PIKK family atypical protein kinase 0.3713 0.5898 0.5896
Loa Loa (eye worm) hypothetical protein 0.0548 0.0833 0.0833
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0405 0.0604 0.0603
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0405 0.0604 0.06
Brugia malayi hypothetical protein 0.0242 0.0343 0.0342
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0017 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0081 0.0086 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.2105 0.3324 0.3322
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0405 0.0604 0.06
Echinococcus granulosus lysine specific histone demethylase 1A 0.0164 0.0218 0.0217
Plasmodium vivax acyl-CoA synthetase, putative 0.0054 0.0042 0.0672
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0405 0.0604 0.06
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0405 0.0604 0.0603
Echinococcus multilocularis ecdysone induced protein 78C 0.0512 0.0776 0.0775
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0405 0.0604 0.06
Schistosoma mansoni rest corepressor (corest) protein 0.0031 0.0006 0.0005
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.003 0.0004 0.00000022677
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0512 0.0776 0.0775
Schistosoma mansoni immunophilin 0.0052 0.004 0.0039
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0119 0.0146 0.0146
Loa Loa (eye worm) hypothetical protein 0.0251 0.0358 0.0358
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0405 0.0604 0.0603
Trichomonas vaginalis PIKK family atypical protein kinase 0.1684 0.2651 0.2648
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0061 0.0053 0.0052
Loa Loa (eye worm) hypothetical protein 0.0155 0.0203 0.0203
Echinococcus granulosus mesoderm induction early response protein 1 0.0031 0.0006 0.0005
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0405 0.0604 0.0603
Brugia malayi nuclear hormone receptor 0.0512 0.0776 0.0775
Brugia malayi Calcitonin receptor-like protein seb-1 0.0251 0.0358 0.0357
Onchocerca volvulus 0.0037 0.0016 0.0088
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0405 0.0604 0.06
Schistosoma mansoni hypothetical protein 0.0079 0.0083 0.0082
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.6277 1 1
Brugia malayi beta-lactamase 0.0037 0.0016 0.0015
Brugia malayi hypothetical protein 0.0271 0.0389 0.0388
Trichomonas vaginalis conserved hypothetical protein 0.1323 0.2073 0.207
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0081 0.0085 0.0085
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.2105 0.3324 0.3323
Echinococcus granulosus metastasis associated protein MTA1 0.0031 0.0006 0.0005
Entamoeba histolytica hypothetical protein 0.0036 0.0014 0.001
Entamoeba histolytica hypothetical protein 0.0036 0.0014 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.1187 0.1856 0.1852
Echinococcus granulosus sterol regulatory element binding protein 0.0129 0.0162 0.0161
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0405 0.0604 0.06
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.1642 0.2584 0.2583
Schistosoma mansoni hypothetical protein 0.0918 0.1425 0.1424
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0072 0.0072 0.0242
Brugia malayi hypothetical protein 0.0548 0.0833 0.0832
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0016 0.0014
Mycobacterium tuberculosis Conserved hypothetical protein 0.0164 0.0218 0.0818
Leishmania major hypothetical protein, conserved 0.0405 0.0604 0.0589
Giardia lamblia Phosphatidylinositol 4-kinase 0.0405 0.0604 0.06
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0271 0.0389 0.0388
Mycobacterium tuberculosis Conserved hypothetical protein 0.0405 0.0604 0.2341
Loa Loa (eye worm) hypothetical protein 0.0341 0.0502 0.0502
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.005 0.0049
Brugia malayi MH2 domain containing protein 0.0243 0.0345 0.0344
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0405 0.0604 0.06
Schistosoma mansoni microtubule-associated protein tau 0.1395 0.2188 0.2187
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0041 0.0021 0.002
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0405 0.0604 0.0603
Onchocerca volvulus Huntingtin homolog 0.0127 0.016 0.0934
Plasmodium vivax hypothetical protein 0.0031 0.0006 0.0061
Schistosoma mansoni inositol monophosphatase 0.0038 0.0017 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0512 0.0776 0.0775
Echinococcus granulosus hypothetical protein 0.0726 0.1118 0.1117
Brugia malayi Doublecortin family protein 0.0041 0.0022 0.0021
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0512 0.0776 0.0775
Leishmania major fk506-binding protein 1-like protein 0.0061 0.0053 0.0037
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0405 0.0604 0.0603
Brugia malayi hypothetical protein 0.0164 0.0218 0.0217
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0242 0.0343 0.0342
Loa Loa (eye worm) hypothetical protein 0.0512 0.0776 0.0776
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0111 0.0133 0.0129
Schistosoma mansoni patched 1 0.0129 0.0162 0.0161
Trichomonas vaginalis PIKK family atypical protein kinase 0.5359 0.8531 0.8531
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0405 0.0604 0.06
Echinococcus multilocularis expressed conserved protein 0.0282 0.0407 0.0406
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0022 0.0021
Loa Loa (eye worm) hypothetical protein 0.0512 0.0776 0.0776
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0072 0.0072 0.0241
Onchocerca volvulus 0.0037 0.0016 0.0088
Schistosoma mansoni chromosome transmission fidelity factor 0.003 0.0004 0.0003
Brugia malayi nuclear receptor RXR 0.0271 0.0389 0.0388
Trichomonas vaginalis PIKK family atypical protein kinase 0.4993 0.7945 0.7944
Brugia malayi Nuclear hormone receptor-like 1 0.0512 0.0776 0.0775
Onchocerca volvulus 0.0477 0.0719 0.4219
Loa Loa (eye worm) hypothetical protein 0.0029 0.0002 0.0002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.005 0.0165
Echinococcus granulosus microtubule associated protein 2 0.1395 0.2188 0.2187
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0022 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.3713 0.5898 0.5896
Trichomonas vaginalis PIKK family atypical protein kinase 0.4669 0.7426 0.7425
Loa Loa (eye worm) hypothetical protein 0.1061 0.1654 0.1654
Loa Loa (eye worm) inositol-1 0.0038 0.0017 0.0017
Schistosoma mansoni rab6-interacting 0.0041 0.0022 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.4669 0.7426 0.7425
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0918 0.1425 0.1424
Echinococcus multilocularis GPCR, family 2 0.0079 0.0083 0.0082
Schistosoma mansoni nuclear hormone receptor 0.0242 0.0343 0.0342
Onchocerca volvulus Mesoderm induction early response 1 related homolog 0.0031 0.0006 0.0028
Echinococcus granulosus sterol O acyltransferase 1 0.0213 0.0297 0.0296
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0251 0.0358 0.0358
Trichomonas vaginalis PIKK family atypical protein kinase 0.3384 0.5371 0.5369
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0016 0.0012
Entamoeba histolytica hypothetical protein 0.0405 0.0604 0.06
Echinococcus multilocularis Glutaredoxin protein 5 0.0041 0.0021 0.002
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0512 0.0776 0.0775
Trichomonas vaginalis PIKK family atypical protein kinase 0.3389 0.5379 0.5378
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0405 0.0604 1
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0081 0.0085 0.0085
Loa Loa (eye worm) phosphatidylinositol 3 0.0405 0.0604 0.0604
Trichomonas vaginalis PIKK family atypical protein kinase 0.1187 0.1856 0.1852
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.2105 0.3324 0.3324
Schistosoma mansoni rab6-interacting 0.0041 0.0022 0.0021
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0512 0.0776 0.0775
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0016 0.0015
Entamoeba histolytica acyl-coA synthetase, putative 0.0072 0.0072 0.0068
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0164 0.0218 0.3585
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0016 0.0015
Plasmodium falciparum amino acid transporter, putative 0.0081 0.0085 0.1389
Onchocerca volvulus 0.0041 0.0022 0.0122
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0271 0.0389 0.0388
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0405 0.0604 0.0603
Loa Loa (eye worm) GATA zinc finger family protein 0.0031 0.0006 0.0006
Echinococcus granulosus voltage gated potassium channel 0.0034 0.0011 0.001
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0016 0.0232
Trypanosoma brucei rac serine-threonine kinase, putative 0.0066 0.0061 0.0059
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.1619 0.2547 1
Brugia malayi hypothetical protein 0.0242 0.0343 0.0342
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0061 0.0053 0.0049
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0164 0.0218 0.0291
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0405 0.0604 0.0603
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0405 0.0604 0.06
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0072 0.0241
Loa Loa (eye worm) phosphatidylinositol 3 0.0405 0.0604 0.0604
Echinococcus multilocularis snurportin 1 0.0306 0.0446 0.0445
Echinococcus granulosus nibrin 0.003 0.0004 0.0003
Schistosoma mansoni lipoxygenase 0.0181 0.0246 0.0245
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0072 0.0056
Entamoeba histolytica acyl-CoA synthetase, putative 0.0072 0.0072 0.0068
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0405 0.0604 0.0603
Brugia malayi Niemann-Pick C1 protein precursor 0.03 0.0436 0.0435
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0512 0.0776 0.0775
Schistosoma mansoni hypothetical protein 0.0115 0.014 0.0139
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0405 0.0604 0.0603
Schistosoma mansoni amine oxidase 0.0164 0.0218 0.0217
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0081 0.0085 0.0085
Trypanosoma brucei RNA helicase, putative 0.0115 0.014 0.0138
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0016 0.0198
Trichomonas vaginalis PIKK family atypical protein kinase 0.4669 0.7426 0.7425
Brugia malayi hypothetical protein 0.0041 0.0022 0.0021
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.6277 1 1
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.005 0.0049
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0271 0.0389 0.0389
Trichomonas vaginalis conserved hypothetical protein 0.0918 0.1425 0.1421
Loa Loa (eye worm) DR-78 0.0242 0.0343 0.0343
Entamoeba histolytica PH domain containing protein kinase, putative 0.0045 0.0028 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0782 0.1208 0.1204
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0061 0.0053 0.0052
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0405 0.0604 0.0603
Mycobacterium ulcerans hypothetical protein 0.0037 0.0016 0.0042
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0081 0.0085 0.0085
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0421 0.0418
Loa Loa (eye worm) hypothetical protein 0.0081 0.0085 0.0085
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0405 0.0604 0.06
Plasmodium vivax multidomain scavenger receptor, putative 0.0041 0.0022 0.0328
Loa Loa (eye worm) glutaminase 2 0.028 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.003 0.0004 0.0004
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0002 0.0001
Brugia malayi Nuclear hormone receptor-like 1 0.0271 0.0389 0.0388
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0061 0.0053 0.0052
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0181 0.0246 0.0245
Brugia malayi Serotonin receptor 0.049 0.0739 0.0739
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0512 0.0776 0.0775
Schistosoma mansoni hypothetical protein 0.0041 0.0022 0.0021
Loa Loa (eye worm) hypothetical protein 0.0054 0.0042 0.0042
Entamoeba histolytica hypothetical protein 0.1187 0.1856 0.1852
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0072 0.0072 0.0241
Loa Loa (eye worm) MH2 domain-containing protein 0.0243 0.0345 0.0345
Trichomonas vaginalis fk506-binding protein, putative 0.0061 0.0053 0.0049
Onchocerca volvulus 0.0037 0.0016 0.0088
Loa Loa (eye worm) hypothetical protein 0.0031 0.0006 0.0006
Echinococcus granulosus expressed conserved protein 0.0282 0.0407 0.0406
Brugia malayi follicle stimulating hormone receptor 0.026 0.0372 0.0371
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0081 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.003 0.0004 0.0004
Loa Loa (eye worm) solute carrier family 6 member 4 0.0477 0.0719 0.0719
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0031 0.0006 0.0005
Brugia malayi amine oxidase, flavin-containing family protein 0.0181 0.0245 0.0244
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0129 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0158 0.0208 0.0208
Echinococcus multilocularis sodium and chloride dependent glycine 0.0081 0.0085 0.0085
Schistosoma mansoni hypothetical protein 0.0079 0.0083 0.0082
Echinococcus multilocularis conserved hypothetical protein 0.0709 0.1091 0.109
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0081 0.0085 0.0085
Echinococcus multilocularis metastasis associated protein 1 (mta1) 0.0031 0.0006 0.0005
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0512 0.0776 0.0775
Trichomonas vaginalis PIKK family atypical protein kinase 0.4993 0.7945 0.7944
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0512 0.0776 0.0775
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.003 0.0004 0.0002
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0405 0.0604 0.0602
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0306 0.0446 0.0446
Loa Loa (eye worm) hypothetical protein 0.0031 0.0006 0.0006
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0031 0.0006 0.0005
Giardia lamblia Hypothetical protein 0.0405 0.0604 0.06
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0119 0.0146 0.0145
Echinococcus multilocularis mesoderm induction early response protein 1 0.0031 0.0006 0.0005
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0242 0.0343 0.0342
Onchocerca volvulus 0.0405 0.0604 0.3543
Echinococcus multilocularis fk506 binding protein 0.0061 0.0053 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.3751 0.5958 0.5956
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0054 0.0042 0.1795
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0072 0.0072 0.0242
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0034 0.0011 0.001
Onchocerca volvulus 0.0155 0.0203 0.119
Loa Loa (eye worm) hypothetical protein 0.0242 0.0343 0.0343
Trichomonas vaginalis glutaminase, putative 0.028 0.0405 0.0401
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0081 0.0085 0.0085
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.6277 1 1
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0061 0.0053 0.0049
Schistosoma mansoni hypothetical protein 0.0514 0.0778 0.0778
Loa Loa (eye worm) hypothetical protein 0.0271 0.0389 0.0389
Echinococcus multilocularis Zinc finger, PHD finger 0.0405 0.0604 0.0603
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0061 0.0053 0.0684
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0017 0.0001
Brugia malayi nuclear hormone receptor 0.0242 0.0343 0.0342
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0405 0.0604 0.0811
Loa Loa (eye worm) hypothetical protein 0.0103 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0054 0.0042 0.0042
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0477 0.0719 0.0718
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.6277 1 1
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0405 0.0604 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0079 0.0083 0.0082
Leishmania major phosphatidylinositol kinase related protein, putative 0.0405 0.0604 0.0589
Schistosoma mansoni zinc finger protein 0.0031 0.0006 0.0005
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0405 0.0604 0.06
Loa Loa (eye worm) hypothetical protein 0.0242 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.003 0.0004 0.0004
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0081 0.0085 0.0113
Mycobacterium leprae conserved hypothetical protein 0.0405 0.0604 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0512 0.0776 0.0775
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0017 0.0015
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0061 0.0053 0.0052
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0016 0.0012
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0405 0.0604 0.06
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0405 0.0604 0.06
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0512 0.0776 0.0776
Echinococcus multilocularis sodium and chloride dependent glycine 0.0081 0.0085 0.0085
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0405 0.0604 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0072 0.0072
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.0072 0.1127
Echinococcus multilocularis sterol O acyltransferase 1 0.0213 0.0297 0.0296
Echinococcus granulosus RUN 0.0041 0.0022 0.0021
Toxoplasma gondii histone lysine-specific demethylase 0.0164 0.0218 0.0291
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0324 0.0474 0.0474
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0242 0.0343 0.0342
Schistosoma mansoni thyroid hormone receptor 0.0512 0.0776 0.0775
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0061 0.0053 0.0174
Treponema pallidum sodium- and chloride- dependent transporter 0.0477 0.0719 1
Loa Loa (eye worm) hypothetical protein 0.0242 0.0343 0.0343
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0072 0.0071
Loa Loa (eye worm) hypothetical protein 0.0242 0.0343 0.0343
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0405 0.0604 0.0603
Mycobacterium tuberculosis Possible oxidoreductase 0.0164 0.0218 0.0818
Toxoplasma gondii ATPase, AAA family protein 0.003 0.0004 0.0003
Brugia malayi steroid hormone receptor 0.0512 0.0776 0.0775
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0239 0.0339 0.1295
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.6277 1 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0038 0.0108
Echinococcus multilocularis nibrin 0.003 0.0004 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0512 0.0776 0.0776
Trichomonas vaginalis PIKK family atypical protein kinase 0.4993 0.7945 0.7944
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0242 0.0343 0.0343
Brugia malayi hypothetical protein 0.0127 0.016 0.0159
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0405 0.0604 0.0603
Echinococcus granulosus geminin 0.0514 0.0778 0.0778
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0016 0.0012
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0061 0.0053 0.0049
Plasmodium falciparum protoporphyrinogen oxidase 0.0164 0.0218 0.3585
Mycobacterium ulcerans monoamine oxidase 0.0164 0.0218 0.0762
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0017 0.0013
Loa Loa (eye worm) glutaminase 0.028 0.0405 0.0405
Trichomonas vaginalis replication factor C large subunit, putative 0.003 0.0004 0.00000022677
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0072 0.0056
Schistosoma mansoni immunophilin 0.0061 0.0053 0.0052
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0081 0.0085 0.0085
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.2105 0.3324 0.3324
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0405 0.0604 0.06
Loa Loa (eye worm) hypothetical protein 0.0037 0.0016 0.0016
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0512 0.0776 0.0775
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0081 0.0085 0.0085
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0512 0.0776 0.0775
Brugia malayi nuclear receptor RXR 0.0242 0.0343 0.0342
Echinococcus granulosus importin subunit beta 1 0.0029 0.0002 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.6277 1 1
Loa Loa (eye worm) hypothetical protein 0.0512 0.0776 0.0776
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0061 0.0053 0.0049
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0405 0.0604 0.06
Echinococcus granulosus zinc finger protein 541 0.0031 0.0006 0.0005
Mycobacterium ulcerans dehydrogenase 0.0164 0.0218 0.0762
Loa Loa (eye worm) hypothetical protein 0.0324 0.0474 0.0474
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0072 0.0241
Schistosoma mansoni rest corepressor (corest) protein 0.0031 0.0006 0.0005
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0081 0.0085 0.3814
Echinococcus granulosus serine threonine protein kinase nrc 0.0041 0.0022 0.0021
Echinococcus granulosus Nuclear hormone receptor HR96 0.0242 0.0343 0.0342
Toxoplasma gondii ABC1 family protein 0.0037 0.0016 0.0019
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0016 0.0042
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0052 0.004 0.0039
Loa Loa (eye worm) nuclear hormone receptor 0.0242 0.0343 0.0343
Echinococcus multilocularis SANT, DNA binding 0.0031 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0405 0.0604 0.0604
Loa Loa (eye worm) hypothetical protein 0.0918 0.1425 0.1425
Echinococcus multilocularis protoporphyrinogen oxidase 0.0164 0.0218 0.0217
Loa Loa (eye worm) hypothetical protein 0.003 0.0004 0.0004
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0081 0.0085 0.0085
Brugia malayi Myb-like DNA-binding domain containing protein 0.1061 0.1654 0.1653
Leishmania major phosphatidylinositol 3-kinase, putative 0.0405 0.0604 0.0589
Entamoeba histolytica protein kinase 2, putative 0.0041 0.0022 0.0018
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.003 0.0004 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0512 0.0776 0.0775
Leishmania major phosphatidylinositol 3-related kinase, putative 0.2105 0.3324 0.3314
Brugia malayi Nuclear hormone receptor E75 0.0242 0.0343 0.0342
Echinococcus multilocularis neuropeptide s receptor 0.0489 0.0738 0.0737
Echinococcus multilocularis nervana 2 0.0041 0.0021 0.002
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.1187 0.1856 0.1854
Echinococcus granulosus neuropeptide s receptor 0.0489 0.0738 0.0737
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0079 0.0083 0.0082
Echinococcus granulosus sodium and chloride dependent glycine 0.0081 0.0085 0.0085
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0242 0.0343 0.0342
Leishmania major hypothetical protein, unknown function 0.0405 0.0604 0.0589
Trichomonas vaginalis PIKK family atypical protein kinase 0.6277 1 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0512 0.0776 0.0775
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0405 0.0604 0.0602
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0061 0.0057
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0072 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0512 0.0776 0.0776
Trichomonas vaginalis PIKK family atypical protein kinase 0.2105 0.3324 0.3322
Brugia malayi CHE-14 protein 0.0129 0.0162 0.0161
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0016 0.0012
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0512 0.0776 0.0775
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0405 0.0604 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0016 0.0016
Plasmodium vivax hypothetical protein 0.0405 0.0604 1
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0164 0.0218 0.0762
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0405 0.0604 0.0603
Brugia malayi SWIRM domain containing protein 0.0341 0.0502 0.0501
Echinococcus multilocularis FTZ F1 alpha 0.0512 0.0776 0.0775
Loa Loa (eye worm) hypothetical protein 0.0242 0.0343 0.0343
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0045 0.0028 0.0024
Brugia malayi tailless protein 0.0242 0.0343 0.0342
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0324 0.0474 0.0474
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0405 0.0604 0.06
Loa Loa (eye worm) phosphatidylinositol 3 0.0405 0.0604 0.0604
Plasmodium falciparum LCCL domain-containing protein 0.0041 0.0022 0.0328
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0405 0.0604 0.06
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0512 0.0776 0.0775
Schistosoma mansoni hypothetical protein 0.0124 0.0155 0.0154
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.6277 1 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0512 0.0776 0.0775
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0405 0.0604 1
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.1187 0.1856 0.1852
Schistosoma mansoni sodium-dependent amino acid transporter 0.0081 0.0085 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0512 0.0776 0.0775
Schistosoma mansoni polycystin 1-related 0.0041 0.0022 0.0021
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0142 0.0183 0.064
Brugia malayi hypothetical protein 0.0271 0.0389 0.0388
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0081 0.0085 0.0085
Onchocerca volvulus 0.0072 0.0072 0.0415
Echinococcus granulosus REST corepressor 3 0.0031 0.0006 0.0005
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0405 0.0604 0.06
Trypanosoma brucei target of rapamycin kinase 3, putative 0.4998 0.7953 0.7953
Plasmodium vivax hypothetical protein, conserved 0.0164 0.0218 0.3585
Onchocerca volvulus Protein ultraspiracle homolog 0.0512 0.0776 0.4552
Giardia lamblia Fructose-bisphosphate aldolase 0.0291 0.0421 0.0418
Brugia malayi orphan nuclear receptor NR2E1 0.0242 0.0343 0.0342
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0059 0.005 0.0034
Brugia malayi hypothetical protein 0.003 0.0004 0.0003
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0512 0.0776 0.0775
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0512 0.0776 0.0776
Echinococcus multilocularis RUN 0.0041 0.0022 0.0021
Echinococcus multilocularis thyroid hormone receptor alpha 0.0512 0.0776 0.0775
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0421 0.0418
Schistosoma mansoni hypothetical protein 0.0514 0.0778 0.0778
Loa Loa (eye worm) hypothetical protein 0.003 0.0004 0.0004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0405 0.0604 0.0603
Brugia malayi hypothetical protein 0.0036 0.0014 0.0013
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0072 0.0241
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.6277 1 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0081 0.0085 0.0085
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0405 0.0604 0.0603
Schistosoma mansoni voltage-gated potassium channel 0.013 0.0163 0.0162
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0016 0.0015
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0041 0.0022 0.0018
Entamoeba histolytica hypothetical protein 0.0405 0.0604 0.06
Trypanosoma cruzi target of rapamycin kinase 3 0.4998 0.7953 0.7952
Brugia malayi p70 ribosomal S6 kinase beta 0.0062 0.0055 0.0054
Echinococcus multilocularis Niemann Pick C1 protein 0.03 0.0436 0.0435
Plasmodium falciparum transporter, putative 0.0081 0.0085 0.1389
Loa Loa (eye worm) hypothetical protein 0.0242 0.0343 0.0343
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0034 0.0011 0.001
Brugia malayi conserved hypotetical protein 0.0242 0.0343 0.0342
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.1187 0.1856 0.1852
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0242 0.0343 0.0342
Brugia malayi topoisomerase 0.003 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0477 0.0719 0.0719
Mycobacterium ulcerans hydrolase/amidase 0.0287 0.0415 0.1466
Schistosoma mansoni importin beta-1 0.0029 0.0002 0.0001
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0017 0.0013
Loa Loa (eye worm) hypothetical protein 0.0037 0.0016 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.3389 0.5379 0.5378
Brugia malayi hypothetical protein 0.0041 0.0022 0.0021
Toxoplasma gondii target of rapamycin (TOR), putative 0.4669 0.7426 1
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0164 0.0218 0.0217
Schistosoma mansoni immunophilin 0.0061 0.0053 0.0052
Schistosoma mansoni RAR-like nuclear receptor 0.0512 0.0776 0.0775
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0782 0.1208 0.1204
Brugia malayi nuclear receptor NHR-88 0.0242 0.0343 0.0342
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0405 0.0604 0.0811
Loa Loa (eye worm) hypothetical protein 0.0477 0.0719 0.0719
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0405 0.0604 0.06
Echinococcus granulosus serine:threonine protein kinase SMG1 0.1187 0.1856 0.1855
Loa Loa (eye worm) hypothetical protein 0.0512 0.0776 0.0776
Brugia malayi Myb-like DNA-binding domain containing protein 0.0031 0.0006 0.0005
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0041 0.0022 0.0329
Loa Loa (eye worm) transcription factor SMAD2 0.0243 0.0345 0.0345
Plasmodium vivax hypothetical protein, conserved 0.0405 0.0604 1
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0061 0.0053 0.0052
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0017 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0782 0.1208 0.1204
Schistosoma mansoni hypothetical protein 0.0124 0.0155 0.0154
Trichomonas vaginalis PIKK family atypical protein kinase 0.3389 0.5379 0.5378
Echinococcus granulosus Niemann Pick C1 protein 0.0429 0.0642 0.0641
Onchocerca volvulus 0.003 0.0004 0.0018
Brugia malayi FAT domain containing protein 0.0918 0.1425 0.1424
Echinococcus granulosus serine/threonine protein kinase 0.0045 0.0028 0.0027
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.2105 0.3324 0.3323
Loa Loa (eye worm) hypothetical protein 0.0081 0.0085 0.0085
Brugia malayi Inositol-1 0.0038 0.0017 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0405 0.0604 0.06
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1187 0.1856 0.1855
Echinococcus granulosus replication factor c subunit 1 0.003 0.0004 0.0003
Onchocerca volvulus 0.0081 0.0085 0.0497
Schistosoma mansoni glutaminase 0.028 0.0405 0.0404
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0405 0.0604 0.0811
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0072 0.0072 0.0241
Mycobacterium tuberculosis Conserved protein 0.0037 0.0016 0.0022
Brugia malayi beta-lactamase family protein 0.0037 0.0016 0.0015
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.005 0.0049
Brugia malayi RNA, U transporter 1 0.0082 0.0087 0.0086
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.003 0.0004 0.00000022677
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0061 0.0057
Schistosoma mansoni fkbp-rapamycin associated protein 0.1187 0.1856 0.1855
Brugia malayi beta-lactamase family protein 0.0037 0.0016 0.0015
Toxoplasma gondii AGC kinase 0.0062 0.0055 0.0071
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0242 0.0343 0.0342
Trypanosoma cruzi UDP-galactopyranose mutase 0.0164 0.0218 0.0214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0405 0.0604 0.06
Loa Loa (eye worm) FKBP5 protein 0.0061 0.0053 0.0053
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0016 0.0015
Schistosoma mansoni voltage-gated potassium channel 0.013 0.0163 0.0162
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0512 0.0776 0.0775
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0053 0.0049
Echinococcus granulosus tumor protein p63 0.0342 0.0503 0.0502
Entamoeba histolytica PH domain containing protein kinase, putative 0.0045 0.0028 0.0024
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0079 0.0083 0.0082
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0061 0.0057
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.1187 0.1856 0.1855
Echinococcus multilocularis Niemann Pick C1 protein 0.0429 0.0642 0.0641
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0405 0.0604 0.06
Leishmania major phosphatidylinositol kinase, putative 0.0405 0.0604 0.0589
Loa Loa (eye worm) phosphatidylinositol 3 0.2105 0.3324 0.3324
Brugia malayi Nuclear hormone receptor-like 1 0.0271 0.0389 0.0388
Loa Loa (eye worm) hypothetical protein 0.0081 0.0085 0.0085
Onchocerca volvulus 0.0081 0.0085 0.0497
Trichomonas vaginalis PIKK family atypical protein kinase 0.3751 0.5958 0.5956
Schistosoma mansoni zinc finger protein 0.0242 0.0343 0.0342
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0059 0.005 0.0157
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.001 0.0104
Mycobacterium tuberculosis Conserved protein 0.0037 0.0016 0.0022
Echinococcus granulosus lysine specific histone demethylase 1A 0.0324 0.0474 0.0474
Echinococcus multilocularis zinc finger protein 541 0.0031 0.0006 0.0005
Mycobacterium ulcerans glutaminase 0.028 0.0405 0.1428
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0041 0.0022 0.0329
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0016 0.0012
Loa Loa (eye worm) hypothetical protein 0.0242 0.0343 0.0343
Schistosoma mansoni nuclear hormone receptor 0.0512 0.0776 0.0775
Loa Loa (eye worm) hypothetical protein 0.0072 0.0072 0.0072
Echinococcus multilocularis metastasis associated protein MTA1 0.0031 0.0006 0.0005
Onchocerca volvulus 0.0242 0.0343 0.2008
Trichomonas vaginalis immunophilin, putative 0.0061 0.0053 0.0049
Loa Loa (eye worm) nuclear receptor NHR-67 0.0242 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.0213 0.0297 0.0297
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0034 0.0011 0.001
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0142 0.0183 0.0683
Schistosoma mansoni nuclear receptor nhr-48 0.0242 0.0343 0.0342
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0017 0.0016
Onchocerca volvulus 0.005 0.0036 0.0207
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0081 0.0085 0.0085
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0053 0.0049
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.6277 1 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.2105 0.3324 0.3322
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0512 0.0776 0.0776
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0062 0.0055 0.0055
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0061 0.0053 0.0847
Loa Loa (eye worm) hypothetical protein 0.0242 0.0343 0.0343
Brugia malayi nuclear receptor NHR-88 0.0512 0.0776 0.0775
Loa Loa (eye worm) doublecortin family protein 0.0041 0.0022 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0512 0.0776 0.0775
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0061 0.0053 0.0049
Plasmodium vivax hypothetical protein, conserved 0.0081 0.0085 0.1389
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0038 0.0108
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0421 0.0418
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0291 0.0421 0.0418
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.1187 0.1856 0.1855
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0014 0.0013
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0041 0.0022 0.0021
Loa Loa (eye worm) hypothetical protein 0.0242 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.0072 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.003 0.0004 0.0004
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0405 0.0604 0.0589
Echinococcus granulosus SANT DNA binding 0.0031 0.0006 0.0005
Entamoeba histolytica acyl-CoA synthetase, putative 0.0072 0.0072 0.0068
Echinococcus multilocularis nuclear receptor nhr 48 0.0242 0.0343 0.0342
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0061 0.0053 0.0049
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1187 0.1856 0.1855
Entamoeba histolytica protein kinase, putative 0.0062 0.0055 0.0051
Onchocerca volvulus 0.0341 0.0502 0.2943
Loa Loa (eye worm) hypothetical protein 0.03 0.0436 0.0436
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0512 0.0776 0.0776
Echinococcus granulosus nervana 2 0.0041 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.1279 0.2003 0.2003
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0512 0.0776 0.0775
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0405 0.0604 0.0603
Loa Loa (eye worm) hypothetical protein 0.0512 0.0776 0.0776
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0405 0.0604 0.0604
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0079 0.0083 0.0082
Brugia malayi nuclear receptor NHR-67 0.0242 0.0343 0.0342
Onchocerca volvulus 0.0405 0.0604 0.3543
Loa Loa (eye worm) hypothetical protein 0.0041 0.0022 0.0022
Brugia malayi photoreceptor-specific nuclear receptor 0.0512 0.0776 0.0775
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0164 0.0218 0.3585
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0044 0.0044
Schistosoma mansoni hypothetical protein 0.0079 0.0083 0.0082
Echinococcus granulosus FTZ F1 alpha 0.0512 0.0776 0.0775
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0016 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.4993 0.7945 0.7944
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0016 0.0016
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0405 0.0604 0.0811
Onchocerca volvulus 0.0081 0.0085 0.0497
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0061 0.0057
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0405 0.0604 1
Toxoplasma gondii hypothetical protein 0.0081 0.0085 0.0113
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0405 0.0604 0.06
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0061 0.0057
Echinococcus granulosus thyroid hormone receptor alpha 0.0242 0.0343 0.0342
Brugia malayi nuclear hormone receptor family member nhr-6 0.0242 0.0343 0.0342
Brugia malayi Importin beta-1 subunit 0.0029 0.0002 0.0001
Trypanosoma cruzi Protein kinase B 0.0045 0.0028 0.0024
Echinococcus multilocularis geminin 0.0514 0.0778 0.0778
Echinococcus multilocularis voltage gated potassium channel 0.0034 0.0011 0.001
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0242 0.0343 0.2008
Plasmodium falciparum replication factor C subunit 1, putative 0.003 0.0004 0.0034
Entamoeba histolytica protein kinase rad3, putative 0.1187 0.1856 0.1852
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0271 0.0389 0.0388
Schistosoma mansoni hypothetical protein 0.0306 0.0446 0.0445
Mycobacterium ulcerans hypothetical protein 0.0072 0.0072 0.0241
Loa Loa (eye worm) hypothetical protein 0.0079 0.0083 0.0083
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0061 0.0053 0.0049
Loa Loa (eye worm) hypothetical protein 0.0081 0.0085 0.0085
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0081 0.0085 0.0085
Brugia malayi Nuclear hormone receptor E75 0.0242 0.0343 0.0342
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0164 0.0218 0.3585
Echinococcus multilocularis nervana 2 0.0041 0.0021 0.002
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0081 0.0085 0.0113
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0041 0.0021 0.002
Brugia malayi ecdysteroid receptor 0.0512 0.0776 0.0775
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0142 0.0183 0.299
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0512 0.0776 0.0775
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0512 0.0776 0.0775
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0164 0.0218 0.3562
Loa Loa (eye worm) follicle stimulating hormone receptor 0.026 0.0372 0.0372
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0072 0.0072 0.0241
Echinococcus multilocularis 0.0164 0.0218 0.0217
Echinococcus granulosus ecdysone induced protein 78C 0.0512 0.0776 0.0775
Trichomonas vaginalis PIKK family atypical protein kinase 0.4669 0.7426 0.7425
Loa Loa (eye worm) hypothetical protein 0.0041 0.0022 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.4669 0.7426 0.7425
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0405 0.0604 0.0603
Loa Loa (eye worm) serotonin transporter b 0.0477 0.0719 0.0719
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0041 0.0022 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0512 0.0776 0.0775
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0001 0.0001
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0081 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0054 0.0042 0.0042
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0017 0.0016
Schistosoma mansoni serine/threonine-protein kinase 0.0045 0.0028 0.0027
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0242 0.0343 0.0342
Onchocerca volvulus 0.0242 0.0343 0.2008
Entamoeba histolytica hypothetical protein 0.0036 0.0014 0.001
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0405 0.0604 0.06
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0038 0.0108
Brugia malayi Latrophilin receptor protein 2 0.0079 0.0083 0.0082
Echinococcus multilocularis protein patched 0.0129 0.0162 0.0161
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1783 0.2809 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0016 0.0016
Brugia malayi ELM2 domain containing protein 0.0031 0.0006 0.0005
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0405 0.0604 0.06
Loa Loa (eye worm) norepinephrine transporter 0.0477 0.0719 0.0719
Trypanosoma cruzi UDP-galactopyranose mutase 0.0164 0.0218 0.0214
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0405 0.0604 0.0602
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0405 0.0604 0.06
Echinococcus granulosus serotonin transporter 0.0477 0.0719 0.0718
Schistosoma mansoni sterol O-acyltransferase 1 0.0213 0.0297 0.0296
Echinococcus granulosus sodium and chloride dependent glycine 0.0081 0.0085 0.0085
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0061 0.0053 0.0049
Echinococcus granulosus Polycystic kidney disease protein 0.0041 0.0022 0.0021
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.6277 1 1
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0405 0.0604 0.0603
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0405 0.0604 0.06
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1783 0.2809 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0081 0.0085 0.0085
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0016 0.0022
Loa Loa (eye worm) hypothetical protein 0.0037 0.0016 0.0016
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0081 0.0085 0.0085
Toxoplasma gondii FATC domain-containing protein 0.1187 0.1856 0.2497
Loa Loa (eye worm) hypothetical protein 0.0782 0.1208 0.1208
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0036 0.0035
Schistosoma mansoni hypothetical protein 0.0124 0.0155 0.0154
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0512 0.0776 0.0775
Echinococcus multilocularis microtubule associated protein 2 0.1395 0.2188 0.2187
Schistosoma mansoni hypothetical protein 0.0036 0.0014 0.0013
Schistosoma mansoni sodium/chloride dependent transporter 0.0477 0.0719 0.0718
Trichomonas vaginalis PIKK family atypical protein kinase 0.421 0.6693 0.6692
Trichomonas vaginalis PIKK family atypical protein kinase 0.4669 0.7426 0.7425
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0405 0.0604 0.0603
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0242 0.0343 0.0342
Loa Loa (eye worm) hypothetical protein 0.0031 0.0006 0.0006
Echinococcus multilocularis 0.0405 0.0604 0.0603
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0081 0.0085 0.0085
Echinococcus multilocularis serotonin transporter 0.0477 0.0719 0.0718
Loa Loa (eye worm) hypothetical protein 0.0054 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0034 0.0011 0.0011
Schistosoma mansoni retinoic acid receptor RXR 0.0512 0.0776 0.0775
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0405 0.0604 0.06
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0052 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.1187 0.1856 0.1856
Echinococcus multilocularis serine protein kinase ATM 0.1187 0.1856 0.1855
Schistosoma mansoni thyroid hormone receptor 0.0512 0.0776 0.0775
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0011 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0421 0.0418
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0061 0.0053 0.0847
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.4998 0.7953 0.795
Schistosoma mansoni hypothetical protein 0.0124 0.0155 0.0154
Leishmania major phosphatidylinositol 4-kinase, putative 0.0405 0.0604 0.0589
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0081 0.0085 0.0085
Echinococcus multilocularis neuropeptide receptor A26 0.0489 0.0738 0.0737
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0405 0.0604 0.0603
Schistosoma mansoni lipoxygenase 0.0107 0.0128 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.2105 0.3324 0.3322
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0421 0.0418
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0079 0.0083 0.0082
Loa Loa (eye worm) hypothetical protein 0.0512 0.0776 0.0776
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0014 0.0013
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0242 0.0343 0.0342
Loa Loa (eye worm) AGC/AKT protein kinase 0.0066 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0192 0.0263 0.0263
Loa Loa (eye worm) hypothetical protein 0.0054 0.0042 0.0042
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0512 0.0776 0.0775
Echinococcus granulosus nervana 2 0.0041 0.0021 0.002
Schistosoma mansoni serine/threonine-protein kinase 0.0045 0.0028 0.0027
Loa Loa (eye worm) phosphatidylinositol 3 0.0405 0.0604 0.0604
Loa Loa (eye worm) hypothetical protein 0.0242 0.0343 0.0343
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0111 0.0133 0.0129
Loa Loa (eye worm) hypothetical protein 0.0512 0.0776 0.0776
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.2105 0.3324 0.3324
Loa Loa (eye worm) hypothetical protein 0.0512 0.0776 0.0776
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0072 0.0056
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.2105 0.3324 0.3322
Echinococcus multilocularis Polycystic kidney disease protein 0.0041 0.0022 0.0021
Echinococcus multilocularis protein dispatched 1 0.0147 0.0191 0.019
Leishmania major phosphatidylinositol 3-kinase, putative 0.2105 0.3324 0.3314
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0081 0.0085 0.0085
Echinococcus granulosus Protein patched homolog 1 0.0129 0.0162 0.0161
Trichomonas vaginalis PIKK family atypical protein kinase 0.4993 0.7945 0.7944
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0081 0.0085 0.0085
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0061 0.0053 0.0053
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0512 0.0776 0.0775
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4132 0.6568 0.6568
Echinococcus granulosus metastasis associated protein 1 mta1 0.0031 0.0006 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.2105 0.3324 0.3322
Loa Loa (eye worm) hypothetical protein 0.0129 0.0162 0.0162
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0405 0.0604 0.06
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0017 0.0045
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0016 0.0012
Mycobacterium ulcerans oxidoreductase 0.0164 0.0218 0.0762
Loa Loa (eye worm) hypothetical protein 0.0127 0.016 0.016
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0014 0.0013
Giardia lamblia GTOR 0.6277 1 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0421 0.0418
Echinococcus granulosus Glutaredoxin protein 5 0.0041 0.0021 0.002
Loa Loa (eye worm) latrophilin receptor protein 2 0.0079 0.0083 0.0083
Giardia lamblia Kinase, AGC PKA 0.0041 0.0022 0.0018
Loa Loa (eye worm) hypothetical protein 0.0242 0.0343 0.0343
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0016 0.0022
Loa Loa (eye worm) hypothetical protein 0.0271 0.0389 0.0389
Schistosoma mansoni inositol monophosphatase 0.0038 0.0017 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.2105 0.3324 0.3322
Leishmania major UDP-galactopyranose mutase 0.0164 0.0218 0.0202
Leishmania major peptidylprolyl isomerase-like protein 0.0061 0.0053 0.0037
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0405 0.0604 0.06
Loa Loa (eye worm) hypothetical protein 0.0405 0.0604 0.0604
Schistosoma mansoni hypothetical protein 0.0079 0.0083 0.0082
Entamoeba histolytica hypothetical protein 0.0036 0.0014 0.001
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0016 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.3384 0.5371 0.5369
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0405 0.0604 0.0603
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0053 0.0051
Echinococcus multilocularis replication factor c subunit 1 0.003 0.0004 0.0003
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0405 0.0604 1
Brugia malayi ecdysone receptor 0.0242 0.0343 0.0342
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0072 0.0071
Loa Loa (eye worm) phosphatidylinositol 3 0.0405 0.0604 0.0604
Echinococcus granulosus serine protein kinase ATM 0.1187 0.1856 0.1855
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0017 0.002
Echinococcus granulosus neuropeptide receptor A26 0.0489 0.0738 0.0737
Trichomonas vaginalis PIKK family atypical protein kinase 0.3389 0.5379 0.5378
Mycobacterium leprae Probable lipase LipE 0.0037 0.0016 0.0198
Loa Loa (eye worm) hypothetical protein 0.0081 0.0085 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0512 0.0776 0.0775
Schistosoma mansoni topbp1 0.003 0.0004 0.0003
Toxoplasma gondii non-specific serine/threonine protein kinase 0.1323 0.2073 0.2789
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0421 0.0418
Brugia malayi Steroid receptor seven-up type 2 0.0512 0.0776 0.0775
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0512 0.0776 0.0775
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0512 0.0776 0.0775

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1 uM Capability to inhibit the binding of [3H]-LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M ChEMBL. 1324316
IC50 (binding) = 1 uM Capability to inhibit the binding of [3H]-LTB4 to guinea pig spleen Leukotriene B4 receptor at the concentration of 10e-5 M ChEMBL. 1324316
Inhibition (binding) = 0 % Tested for 50% inhibition of LTA4 hydrolase at 2*10e-5M concentration in porcine leukocyte homogenates ChEMBL. 1324316
Inhibition (binding) = 0 % Tested for 50% inhibition of LTA4 hydrolase at 2*10e-5M concentration in porcine leukocyte homogenates ChEMBL. 1324316

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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