Detailed information for compound 1846228

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 644.842 | Formula: C35H56N4O7
  • H donors: 5 H acceptors: 5 LogP: 5.43 Rotable bonds: 22
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(CCNC(=O)C1(CO1)C[C@@H]([C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C)CC1CCCCC1)O)C
  • InChi: 1S/C35H56N4O7/c1-23(2)17-18-36-32(43)35(22-45-35)21-29(40)27(19-25-13-9-7-10-14-25)38-30(41)24(3)37-31(42)28(20-26-15-11-8-12-16-26)39-33(44)46-34(4,5)6/h8,11-12,15-16,23-25,27-29,40H,7,9-10,13-14,17-22H2,1-6H3,(H,36,43)(H,37,42)(H,38,41)(H,39,44)/t24-,27-,28-,29-,35?/m0/s1
  • InChiKey: XGYCHBUBDDMFIP-NOEZWDEJSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens renin Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium falciparum plasmepsin II Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium yoelii hypothetical protein Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium knowlesi plasmepsin IV, putative Get druggable targets OG5_126885 All targets in OG5_126885
Neospora caninum Renin, related Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma japonicum Cathepsin D precursor, putative Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium falciparum plasmepsin VI Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium knowlesi aspartyl protease, putative Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma mansoni cathepsin D (A01 family) Get druggable targets OG5_126885 All targets in OG5_126885
Echinococcus granulosus cathepsin d lysosomal aspartyl protease Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma mansoni cathepsin D (A01 family) Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium falciparum plasmepsin IV Get druggable targets OG5_126885 All targets in OG5_126885
Toxoplasma gondii aspartyl protease ASP1 Get druggable targets OG5_126885 All targets in OG5_126885
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126885 All targets in OG5_126885
Theileria parva cathepsin E, putative Get druggable targets OG5_126885 All targets in OG5_126885
Toxoplasma gondii aspartyl proteinase (eimepsin), putative Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium berghei plasmepsin VI Get druggable targets OG5_126885 All targets in OG5_126885
Babesia bovis eukaryotic aspartyl protease family protein Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium vivax aspartyl proteinase, putative Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium yoelii hypothetical protein Get druggable targets OG5_126885 All targets in OG5_126885
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) Get druggable targets OG5_126885 All targets in OG5_126885
Candida albicans vacuolar aspartic proteinase precursor similar to S. cerevisiae PEP4 (YPL154C) Get druggable targets OG5_126885 All targets in OG5_126885
Theileria parva pepsinogen, putative Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium falciparum plasmepsin I Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) Get druggable targets OG5_126885 All targets in OG5_126885
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium yoelii plasmepsin Get druggable targets OG5_126885 All targets in OG5_126885
Schistosoma japonicum ko:K01379 cathepsin D [EC3.4.23.5], putative Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium berghei plasmepsin IV Get druggable targets OG5_126885 All targets in OG5_126885
Neospora caninum Pepsinogen A1, related Get druggable targets OG5_126885 All targets in OG5_126885
Plasmodium vivax plasmepsin IV, putative Get druggable targets OG5_126885 All targets in OG5_126885
Cryptosporidium hominis aspartyl protease precursor Get druggable targets OG5_126885 All targets in OG5_126885
Loa Loa (eye worm) aspartic protease BmAsp-2 Get druggable targets OG5_126885 All targets in OG5_126885
Candida albicans vacuolar aspartic proteinase precursor similar to S. cerevisiae PEP4 (YPL154C) Get druggable targets OG5_126885 All targets in OG5_126885
Cryptosporidium parvum membrane bound aspartyl proteinase with a signal peptide plus transmembrane domain Get druggable targets OG5_126885 All targets in OG5_126885
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum plasmepsin X renin 406 aa 352 aa 26.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni DNA polymerase eta 0.0037 0.0284 0.0389
Brugia malayi Bromodomain containing protein 0.0065 0.067 0.0761
Trichomonas vaginalis D-aminoacylase, putative 0.0023 0.0096 0.0008
Loa Loa (eye worm) hypothetical protein 0.0538 0.7195 0.8215
Brugia malayi Bromodomain containing protein 0.0029 0.0183 0.0205
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0538 0.7195 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0088 0.0039
Giardia lamblia Kinase 0.0538 0.7195 1
Mycobacterium ulcerans esterase/lipase LipP 0.0023 0.0096 0.0043
Loa Loa (eye worm) hypothetical protein 0.0163 0.2028 0.2315
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0148 0.1816 1
Echinococcus granulosus inositol monophosphatase 1 0.0023 0.0088 0.0117
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Schistosoma mansoni bromodomain containing protein 0.0049 0.0449 0.0618
Loa Loa (eye worm) hypothetical protein 0.0538 0.7195 0.8215
Onchocerca volvulus Huntingtin homolog 0.0169 0.2111 0.2108
Echinococcus granulosus cell polarity protein 0.0061 0.0623 0.086
Entamoeba histolytica hypothetical protein 0.0538 0.7195 0.8936
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Brugia malayi Muscleblind-like protein 0.0163 0.2028 0.2311
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Mycobacterium ulcerans aldehyde dehydrogenase 0.0028 0.0168 0.0444
Brugia malayi jmjC domain containing protein 0.0242 0.3117 0.3555
Loa Loa (eye worm) hypothetical protein 0.0023 0.0096 0.0109
Echinococcus granulosus JmjC domain containing protein 4 0.003 0.0189 0.0257
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Trypanosoma cruzi phopshatase, putative 0.0061 0.0623 0.0777
Schistosoma mansoni jumonji domain containing protein 0.003 0.0189 0.0257
Schistosoma mansoni hypothetical protein 0.0061 0.0623 0.086
Trypanosoma cruzi hypothetical protein, conserved 0.0061 0.0623 0.0777
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Leishmania major hypothetical protein, conserved 0.0023 0.0089 0.0027
Loa Loa (eye worm) jmjC domain-containing protein 0.0114 0.1344 0.1535
Trypanosoma brucei Outer row dynein-assembly protein 7 0.0061 0.0623 0.0788
Brugia malayi PHD-finger family protein 0.0022 0.0081 0.0087
Echinococcus granulosus tyrosine protein kinase ABL1 0.0538 0.7195 1
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0061 0.0623 0.0672
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0494 0.056
Echinococcus granulosus tyrosine protein kinase Fyn 0.0538 0.7195 1
Brugia malayi F/Y-rich N-terminus family protein 0.0025 0.0128 0.0142
Loa Loa (eye worm) TK protein kinase 0.0538 0.7195 0.8215
Loa Loa (eye worm) hypothetical protein 0.003 0.0186 0.0212
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0321 0.0235
Giardia lamblia Hypothetical protein 0.0061 0.0623 0.0752
Onchocerca volvulus Alhambra homolog 0.0063 0.0645 0.0641
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0088 0.0039
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Brugia malayi C-terminal src kinase protein 1 0.0538 0.7195 0.8214
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.2232 0.3098
Plasmodium falciparum ataxin-2 like protein, putative 0.0023 0.0089 0.004
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0088 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Echinococcus granulosus variable lymphocyte receptor 0.0061 0.0623 0.086
Schistosoma mansoni inositol monophosphatase 0.0023 0.0088 0.0117
Schistosoma mansoni hypothetical protein 0.0345 0.4536 0.6302
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.1065 0.1475
Entamoeba histolytica tyrosine kinase, putative 0.0538 0.7195 0.8936
Entamoeba histolytica serine/threonine kinase, putative 0.0538 0.7195 0.8936
Loa Loa (eye worm) TK/FER protein kinase 0.0538 0.7195 0.8215
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0061 0.0623 0.086
Trypanosoma cruzi Outer row dynein-assembly protein 7 0.0061 0.0623 0.0777
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0538 0.7195 1
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Schistosoma mansoni hypothetical protein 0.0061 0.0623 0.086
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0538 0.7195 1
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Loa Loa (eye worm) TK/FER protein kinase 0.0538 0.7195 0.8215
Entamoeba histolytica tyrosine kinase, putative 0.0538 0.7195 0.8936
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Brugia malayi beta-lactamase family protein 0.0023 0.0096 0.0105
Leishmania major DNA polymerase kappa, putative 0.0023 0.0088 0.0026
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0538 0.7195 1
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Schistosoma mansoni ras suppressor protein 1 rsu1 0.0061 0.0623 0.086
Onchocerca volvulus 0.0538 0.7195 0.7194
Loa Loa (eye worm) Ras-binding protein SUR-8 0.0061 0.0623 0.0711
Echinococcus granulosus epidermal growth factor receptor 0.0538 0.7195 1
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Onchocerca volvulus 0.0538 0.7195 0.7194
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Trypanosoma cruzi hypothetical protein, conserved 0.0061 0.0623 0.0777
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0178 0.2232 0.2548
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0538 0.7195 0.8214
Echinococcus granulosus muscleblind protein 0.0163 0.2028 0.2814
Loa Loa (eye worm) hypothetical protein 0.0255 0.3295 0.3762
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Toxoplasma gondii histone lysine demethylase JMJD6a 0.003 0.0189 0.0181
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0093 0.1065 0.1475
Schistosoma mansoni flightless-I 0.0061 0.0623 0.086
Trichomonas vaginalis protein phosphatase 2C, putative 0.0061 0.0623 0.0539
Echinococcus multilocularis leucine rich repeat containing protein 57 0.0061 0.0623 0.086
Plasmodium falciparum protein kinase, putative 0.0538 0.7195 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0088 0.0039
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0059 0.059 0.0815
Trypanosoma cruzi protein kinase, putative 0.0538 0.7195 1
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Loa Loa (eye worm) TK/Met protein kinase 0.0538 0.7195 0.8215
Echinococcus multilocularis leucine rich repeat and death domain containing protein 0.0061 0.0623 0.086
Trichomonas vaginalis protein tyrosine kinase, putative 0.0538 0.7195 0.717
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0225 0.288 0.2817
Loa Loa (eye worm) TK protein kinase 0.0538 0.7195 0.8215
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0088 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0088 0.0039
Echinococcus multilocularis chromobox protein 1 0.0068 0.0708 0.0979
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Brugia malayi Pre-SET motif family protein 0.0093 0.1065 0.1212
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Mycobacterium tuberculosis Probable esterase LipL 0.0023 0.0096 0.0228
Echinococcus granulosus Leucine rich repeat typical subtype 0.0061 0.0623 0.086
Mycobacterium ulcerans glutaminase 0.0153 0.1881 1
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Echinococcus multilocularis lysine specific demethylase 6a 0.003 0.0189 0.0257
Leishmania major hypothetical protein, conserved 0.0061 0.0623 0.0777
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0096 0.0324
Schistosoma mansoni leucine-rich repeat protein 0.0061 0.0623 0.086
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0023 0.0096 0.0228
Loa Loa (eye worm) TK protein kinase 0.0538 0.7195 0.8215
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0538 0.7195 1
Echinococcus granulosus leucine rich repeat containing protein 40 0.0061 0.0623 0.086
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0225 0.288 0.2817
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0028 0.0168 0.0637
Entamoeba histolytica leucine rich repeat and phosphatase domain containing protein 0.0061 0.0623 0.0672
Plasmodium falciparum ataxin-2 like protein, putative 0.0023 0.0089 0.004
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0394 0.045
Brugia malayi CCR4 0.0064 0.0663 0.0753
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0061 0.0623 0.0711
Brugia malayi Immunoglobulin I-set domain containing protein 0.0061 0.0623 0.0707
Echinococcus multilocularis heat shock protein 70 0.0538 0.7195 1
Entamoeba histolytica hypothetical protein 0.0538 0.7195 0.8936
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0035 0.0262 0.0359
Echinococcus granulosus leucine rich repeat and coiled coil 0.0061 0.0623 0.086
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0538 0.7195 0.8214
Loa Loa (eye worm) TK/FAK protein kinase 0.0538 0.7195 0.8215
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0321 0.0441
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0538 0.7195 0.8936
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Echinococcus granulosus jumonji domain containing protein 0.0088 0.0985 0.1364
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Entamoeba histolytica leucine-rich repeat containing protein 0.0061 0.0623 0.0672
Brugia malayi Immunoglobulin I-set domain containing protein 0.0538 0.7195 0.8214
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0538 0.7195 1
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0189 0.0216
Echinococcus multilocularis tyrosine kinase 0.0538 0.7195 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0242 0.3117 0.4328
Entamoeba histolytica tyrosine kinase, putative 0.0538 0.7195 0.8936
Trypanosoma brucei glucosidase, putative 0.0039 0.0321 0.0366
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Giardia lamblia Hypothetical protein 0.0061 0.0623 0.0752
Echinococcus multilocularis tyrosine protein kinase csk 0.0538 0.7195 1
Loa Loa (eye worm) TK/FER protein kinase 0.0538 0.7195 0.8215
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0028 0.0168 0.0227
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0538 0.7195 1
Echinococcus multilocularis protein flightless 1 0.0061 0.0623 0.086
Schistosoma mansoni jumonji/arid domain-containing protein 0.0114 0.1344 0.1863
Leishmania major leucine-rich repeat protein, putative 0.0061 0.0623 0.0777
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0321 0.0235
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.0284 0.0301
Trichomonas vaginalis AGC family protein kinase 0.0538 0.7195 0.717
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0146 0.0059
Entamoeba histolytica tyrosine kinase, putative 0.0538 0.7195 0.8936
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.2232 0.3098
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.0061 0.0623 0.0788
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0538 0.7195 0.8936
Brugia malayi Inositol-1 0.0023 0.0088 0.0096
Echinococcus multilocularis leucine rich repeat protein soc 2 0.0061 0.0623 0.086
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0028 0.0168 0.0227
Loa Loa (eye worm) hypothetical protein 0.0061 0.0623 0.0711
Plasmodium vivax ataxin-2 like protein, putative 0.0023 0.0089 0.004
Loa Loa (eye worm) hypothetical protein 0.0061 0.0623 0.0711
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.0061 0.0623 0.0788
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0538 0.7195 1
Echinococcus granulosus tyrosine kinase 0.0538 0.7195 1
Loa Loa (eye worm) TK/RYK protein kinase 0.0538 0.7195 0.8215
Trypanosoma brucei phosphatase, putative 0.0061 0.0623 0.0788
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0242 0.3117 0.4328
Echinococcus multilocularis insulin receptor 0.0538 0.7195 1
Brugia malayi Pre-SET motif family protein 0.0651 0.8759 1
Entamoeba histolytica tyrosine kinase, putative 0.0538 0.7195 0.8936
Schistosoma mansoni jumonji/arid domain-containing protein 0.0114 0.1344 0.1863
Plasmodium falciparum JmjC domain-containing protein, putative 0.003 0.0189 0.0181
Trichomonas vaginalis leucine-rich repeat-containing protein, putative 0.0061 0.0623 0.0539
Echinococcus granulosus dna polymerase kappa 0.0023 0.0088 0.0117
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0538 0.7195 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0028 0.0158 0.0214
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Onchocerca volvulus 0.0061 0.0623 0.0619
Trichomonas vaginalis leucine-rich repeat-containing protein 17, lrc17, putative 0.0061 0.0623 0.0539
Trypanosoma brucei Basal body protein 0.0061 0.0623 0.0788
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0321 0.0235
Trichomonas vaginalis protein phosphatases pp1 regulatory subunit, putative 0.0061 0.0623 0.0539
Leishmania major hypothetical protein, conserved 0.0538 0.7195 1
Leishmania major hypothetical protein, conserved 0.0061 0.0623 0.0777
Loa Loa (eye worm) hypothetical protein 0.0169 0.2111 0.2411
Trichomonas vaginalis leucine-rich repeat-containing protein, putative 0.0061 0.0623 0.0539
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0088 0.0026
Plasmodium vivax aspartyl proteinase, putative 0.0059 0.059 0.0743
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0023 0.0096 0.0008
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0538 0.7195 0.8215
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Schistosoma mansoni protein kinase 0.0538 0.7195 1
Entamoeba histolytica tyrosin kinase, putative 0.0538 0.7195 0.8936
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0339 0.0253
Toxoplasma gondii leucine-rich repeat protein LRR1 0.0061 0.0623 0.0788
Mycobacterium tuberculosis Probable hydrolase 0.0023 0.0096 0.0228
Echinococcus granulosus natriuretic peptide receptor 1 0.0538 0.7195 1
Leishmania major protein kinase, putative 0.0538 0.7195 1
Echinococcus multilocularis leucine rich repeat containing protein 15 0.0061 0.0623 0.086
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Trichomonas vaginalis leucine-rich transmembrane proteins, putative 0.0061 0.0623 0.0539
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0088 0.0039
Entamoeba histolytica receptor protein kinase, putative 0.0538 0.7195 0.8936
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0146 0.0059
Loa Loa (eye worm) hypothetical protein 0.003 0.0189 0.0216
Echinococcus granulosus leucine rich repeat containing protein 24 0.0061 0.0623 0.086
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Toxoplasma gondii aspartyl protease ASP1 0.0059 0.059 0.0743
Echinococcus granulosus tumor protein p63 0.0207 0.2628 0.3649
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0023 0.0096 0.0043
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0538 0.7195 0.8936
Leishmania major hypothetical protein, conserved 0.0061 0.0623 0.0777
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Echinococcus multilocularis ephrin type A receptor 4 A 0.0538 0.7195 1
Brugia malayi AF-10 protein 0.0021 0.006 0.0064
Echinococcus multilocularis leucine rich repeat neuronal protein leucine rich repeat containing protein 0.0061 0.0623 0.086
Onchocerca volvulus 0.0023 0.0096 0.0092
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Giardia lamblia Kinase, NEK 0.0538 0.7195 1
Echinococcus multilocularis leucine rich repeat 0.0061 0.0623 0.086
Schistosoma mansoni shoc2 0.0061 0.0623 0.086
Brugia malayi glutaminase DH11.1 0.0153 0.1881 0.2144
Onchocerca volvulus 0.0538 0.7195 0.7194
Schistosoma mansoni hypothetical protein 0.0061 0.0623 0.086
Echinococcus granulosus retinal guanylyl cyclase 2 0.0538 0.7195 1
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Echinococcus granulosus tyrosine protein kinase Src64B 0.0538 0.7195 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.0538 0.7195 1
Onchocerca volvulus 0.0103 0.1197 0.1193
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0016 0.0004 0.0005
Schistosoma mansoni protein kinase 0.0538 0.7195 1
Trichomonas vaginalis protein kinase atn1, putative 0.0538 0.7195 0.717
Brugia malayi hypothetical protein 0.0538 0.7195 0.8214
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0107 0.1246 0.1727
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Trichomonas vaginalis leucine-rich transmembrane protein, putative 0.0061 0.0623 0.0539
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Echinococcus multilocularis peregrin 0.0065 0.067 0.0926
Entamoeba histolytica protein kinase, putative 0.0599 0.8042 1
Entamoeba histolytica ankyrin repeat protein 0.0538 0.7195 0.8936
Schistosoma mansoni protein kinase 0.0538 0.7195 1
Entamoeba histolytica villidin, putative 0.0061 0.0623 0.0672
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Schistosoma mansoni protein phosphatases pp1 regulatory subunit 0.0061 0.0623 0.086
Entamoeba histolytica hypothetical protein 0.0599 0.8042 1
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.7195 0.717
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0064 0.0663 0.058
Loa Loa (eye worm) hypothetical protein 0.0107 0.1246 0.1423
Entamoeba histolytica villidin, putative 0.0061 0.0623 0.0672
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0321 0.0367
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0104 0.1217 0.1687
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0035 0.0262 0.0359
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Schistosoma mansoni hypothetical protein 0.0052 0.0494 0.0682
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0061 0.0623 0.0711
Trypanosoma cruzi Calcium/calmodulin-dependent protein kinase kinase, putative 0.0061 0.0623 0.0777
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Loa Loa (eye worm) TK/FER protein kinase 0.0538 0.7195 0.8215
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Loa Loa (eye worm) TK/FER protein kinase 0.0538 0.7195 0.8215
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0538 0.7195 0.8936
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0321 0.0235
Trichomonas vaginalis protein phosphatase 2C, putative 0.0061 0.0623 0.0539
Trypanosoma cruzi PAB1-binding protein , putative 0.0023 0.0089 0.0027
Echinococcus granulosus tyrosine protein kinase Fyn 0.0538 0.7195 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0623 0.0711
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0538 0.7195 0.8215
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0061 0.0623 0.0711
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Echinococcus multilocularis Leucine rich repeat, typical subtype 0.0061 0.0623 0.086
Schistosoma mansoni serine/threonine protein kinase 0.0538 0.7195 1
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0538 0.7195 1
Plasmodium falciparum plasmepsin II 0.0059 0.059 0.0743
Loa Loa (eye worm) hypothetical protein 0.0061 0.0623 0.0711
Loa Loa (eye worm) hypothetical protein 0.0063 0.0645 0.0736
Echinococcus multilocularis slit 1 protein 0.0061 0.0623 0.086
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Schistosoma mansoni protein phosphatase 2C 0.003 0.0189 0.0257
Trichomonas vaginalis conserved hypothetical protein 0.0538 0.7195 0.717
Trypanosoma cruzi leucine-rich repeat protein, putative 0.0061 0.0623 0.0777
Toxoplasma gondii LsmAD domain-containing protein 0.0023 0.0089 0.004
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0321 0.0235
Loa Loa (eye worm) RGC/RGC protein kinase 0.0538 0.7195 0.8215
Mycobacterium ulcerans beta-lactamase 0.0023 0.0096 0.0043
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0538 0.7195 0.8936
Echinococcus multilocularis Leucine rich repeat, typical subtype 0.0061 0.0623 0.086
Loa Loa (eye worm) sur-8-PB 0.0061 0.0623 0.0711
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0538 0.7195 0.8214
Entamoeba histolytica hypothetical protein 0.0538 0.7195 0.8936
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0088 0.0026
Schistosoma mansoni ephrin receptor 0.0538 0.7195 1
Echinococcus granulosus tyrosine kinase 0.0538 0.7195 1
Trypanosoma cruzi phopshatase, putative 0.0061 0.0623 0.0777
Trypanosoma brucei DNA polymerase eta, putative 0.0037 0.0284 0.0314
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.003 0.0189 0.0168
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0538 0.7195 1
Leishmania major hypothetical protein, conserved 0.003 0.0189 0.0168
Trypanosoma cruzi protein phosphatase 1, regulatory subunit, putative 0.0061 0.0623 0.0777
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0017 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0623 0.0539
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0088 0.0026
Echinococcus granulosus neuropeptide receptor A26 0.0407 0.5395 0.7497
Echinococcus multilocularis tumor protein p63 0.0207 0.2628 0.3649
Entamoeba histolytica hypothetical protein 0.0599 0.8042 1
Loa Loa (eye worm) TK/FER protein kinase 0.0538 0.7195 0.8215
Leishmania major protein kinase, putative 0.0538 0.7195 1
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0538 0.7195 0.8215
Plasmodium falciparum leucine-rich repeat protein 0.0061 0.0623 0.0788
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0538 0.7195 1
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Loa Loa (eye worm) inositol-1 0.0023 0.0088 0.0101
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0017 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0061 0.0623 0.0711
Brugia malayi beta-lactamase family protein 0.0023 0.0096 0.0105
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0538 0.7195 0.8936
Leishmania major hypothetical protein, conserved 0.0061 0.0623 0.0777
Echinococcus multilocularis ras suppressor protein 1 0.0061 0.0623 0.086
Toxoplasma gondii protein kinase domain-containing protein 0.0538 0.7195 1
Echinococcus granulosus Leucine rich repeat domain containing protein 0.0061 0.0623 0.086
Echinococcus multilocularis peroxidasin 0.0061 0.0623 0.086
Brugia malayi Heterochromatin protein 1 0.0068 0.0708 0.0804
Trichomonas vaginalis conserved hypothetical protein 0.0538 0.7195 0.717
Echinococcus granulosus leucine rich repeat and calponin y 0.0061 0.0623 0.086
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0023 0.0096 0.0228
Loa Loa (eye worm) TK protein kinase 0.0538 0.7195 0.8215
Loa Loa (eye worm) hypothetical protein 0.0023 0.0096 0.0109
Echinococcus granulosus epidermal growth factor receptor 0.0538 0.7195 1
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0538 0.7195 1
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Trichomonas vaginalis leucine-rich transmembrane protein, putative 0.0061 0.0623 0.0539
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Brugia malayi PHD-finger family protein 0.0063 0.0645 0.0732
Leishmania major proteophosphoglycan ppg1 0.0061 0.0623 0.0777
Plasmodium vivax tyrosine kinase-like protein, putative 0.0538 0.7195 1
Schistosoma mansoni ras suppressor protein 1 rsu1 0.0061 0.0623 0.086
Loa Loa (eye worm) hypothetical protein 0.0538 0.7195 0.8215
Loa Loa (eye worm) RGC/RGC protein kinase 0.0538 0.7195 0.8215
Echinococcus multilocularis raf serine:threonine protein kinase 0.0538 0.7195 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0225 0.288 0.3511
Giardia lamblia hypothetical protein 0.0061 0.0623 0.0752
Schistosoma mansoni variable lymphocyte receptor 0.0061 0.0623 0.086
Schistosoma mansoni serine/threonine protein kinase 0.0538 0.7195 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.059 0.0674
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0321 0.0362
Onchocerca volvulus 0.0023 0.0096 0.0092
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Brugia malayi ImpB/MucB/SamB family protein 0.0037 0.0284 0.032
Entamoeba histolytica hypothetical protein, conserved 0.0538 0.7195 0.8936
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0088 0.0117
Echinococcus granulosus receptor type guanylyl cyclase 0.0538 0.7195 1
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0538 0.7195 1
Schistosoma mansoni hypothetical protein 0.0063 0.0645 0.0891
Schistosoma mansoni leucine-rich repeat protein 0.0061 0.0623 0.086
Onchocerca volvulus Peroxidasin homolog 0.0061 0.0623 0.0619
Echinococcus granulosus tyrosine protein kinase Srms 0.0538 0.7195 1
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0088 0.0039
Echinococcus granulosus lysine specific demethylase 6a 0.003 0.0189 0.0257
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0088 0.0184
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.003 0.0189 0.0257
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0035 0.0262 0.0359
Onchocerca volvulus Huntingtin homolog 0.0169 0.2111 0.2108
Brugia malayi Receptor family ligand binding region containing protein 0.0538 0.7195 0.8214
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0035 0.0262 0.0359
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0538 0.7195 1
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0088 0.0117
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0023 0.0096 0.0105
Echinococcus granulosus insulin receptor 0.0538 0.7195 1
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Loa Loa (eye worm) hypothetical protein 0.0538 0.7195 0.8215
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Plasmodium falciparum leucine-rich repeat protein 0.0061 0.0623 0.0788
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0189 0.0216
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0708 0.0626
Toxoplasma gondii PHD-finger domain-containing protein 0.0063 0.0645 0.0819
Entamoeba histolytica hypothetical protein 0.0599 0.8042 1
Schistosoma mansoni hypothetical protein 0.0061 0.0623 0.086
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Schistosoma mansoni slit 0.0061 0.0623 0.086
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Onchocerca volvulus 0.0538 0.7195 0.7194
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0023 0.0088 0.0001
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0088 0.0184
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0061 0.0623 0.0711
Echinococcus multilocularis jumonji domain containing protein 0.0088 0.0985 0.1364
Loa Loa (eye worm) hypothetical protein 0.003 0.0189 0.0216
Echinococcus multilocularis leucine rich repeat protein soc 2 0.0061 0.0623 0.086
Echinococcus multilocularis leucine rich repeat containing protein 40 0.0061 0.0623 0.086
Giardia lamblia PHD finger protein 15 0.0063 0.0645 0.0784
Trypanosoma brucei hypothetical protein, conserved 0.0061 0.0623 0.0788
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.003 0.0189 0.0181
Entamoeba histolytica leucine rich repeat and phosphatase domain containing protein 0.0061 0.0623 0.0672
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Echinococcus multilocularis natriuretic peptide receptor 1 0.0538 0.7195 1
Trichomonas vaginalis leucine-rich repeat containing protein, putative 0.0061 0.0623 0.0539
Entamoeba histolytica hypothetical protein 0.0538 0.7195 0.8936
Brugia malayi hypothetical protein 0.0255 0.3295 0.3759
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0021 0.0069 0.0013
Trypanosoma cruzi kinatase, putative 0.0061 0.0623 0.0777
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0321 0.0235
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0059 0.059 0.0507
Trypanosoma cruzi hypothetical protein, conserved 0.0061 0.0623 0.0777
Schistosoma mansoni hypothetical protein 0.0061 0.0623 0.086
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0321 0.0235
Echinococcus multilocularis neuropeptide receptor A26 0.0407 0.5395 0.7497
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0088 0.0039
Loa Loa (eye worm) TK/FER protein kinase 0.0538 0.7195 0.8215
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Echinococcus granulosus lysosomal alpha glucosidase 0.0178 0.2232 0.3098
Entamoeba histolytica serine/threonine kinase, putative 0.0538 0.7195 0.8936
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Brugia malayi bone morphogenetic protein type 1 receptor 0.0538 0.7195 0.8214
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0538 0.7195 1
Echinococcus multilocularis epidermal growth factor receptor 0.0538 0.7195 1
Loa Loa (eye worm) hypothetical protein 0.0169 0.2111 0.2411
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Trypanosoma cruzi kinatase, putative 0.0061 0.0623 0.0777
Echinococcus multilocularis slit 2 protein 0.0061 0.0623 0.086
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0061 0.0623 0.0672
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0061 0.0623 0.0711
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0538 0.7195 1
Onchocerca volvulus 0.0538 0.7195 0.7194
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0023 0.0096 0.0127
Schistosoma mansoni phd/f-box containing protein 0.003 0.0189 0.0257
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Brugia malayi Raf kinase 0.0538 0.7195 0.8214
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0538 0.7195 1
Schistosoma mansoni hypothetical protein 0.0031 0.0199 0.027
Loa Loa (eye worm) glutaminase 2 0.0153 0.1881 0.2148
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0339 0.0253
Echinococcus granulosus tyrosine protein kinase HCK 0.0538 0.7195 1
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0538 0.7195 0.717
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0061 0.0623 0.0672
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0061 0.0623 0.0788
Toxoplasma gondii ABC1 family protein 0.0023 0.0096 0.005
Loa Loa (eye worm) SRC-1 0.0538 0.7195 0.8215
Echinococcus multilocularis protein phosphatase 1 regulatory subunit 7 0.0061 0.0623 0.086
Entamoeba histolytica leucine-rich repeat containing protein 0.0061 0.0623 0.0672
Entamoeba histolytica tyrosine kinase, putative 0.0538 0.7195 0.8936
Loa Loa (eye worm) hypothetical protein 0.0023 0.0096 0.0109
Echinococcus granulosus leucine rich repeat containing protein 23 0.0061 0.0623 0.086
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0538 0.7195 1
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0023 0.0096 0.0008
Schistosoma mansoni shoc2 0.0061 0.0623 0.086
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0031 0.0209 0.0286
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0538 0.7195 0.8936
Brugia malayi Glycosyl hydrolases family 31 protein 0.0178 0.2232 0.2545
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0538 0.7195 1
Schistosoma mansoni chromobox protein 0.0068 0.0708 0.0979
Onchocerca volvulus 0.0104 0.1217 0.1214
Loa Loa (eye worm) hypothetical protein 0.0022 0.0081 0.0092
Mycobacterium tuberculosis Probable lipase LipD 0.0023 0.0096 0.0228
Trichomonas vaginalis glutaminase, putative 0.0153 0.1881 0.1809
Loa Loa (eye worm) hypothetical protein 0.0023 0.0096 0.0109
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Echinococcus multilocularis leucine rich repeat protein 1 0.0061 0.0623 0.086
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0088 0.0027
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0538 0.7195 0.8215
Echinococcus granulosus neuropeptide s receptor 0.0407 0.5395 0.7497
Onchocerca volvulus 0.0538 0.7195 0.7194
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0061 0.0623 0.086
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0023 0.0096 0.0228
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0538 0.7195 1
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0096 0.0037
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0023 0.0088 0.5
Schistosoma mansoni protein kinase 0.0538 0.7195 1
Echinococcus granulosus activated cdc42 kinase 1 0.0538 0.7195 1
Echinococcus granulosus slit 1 protein 0.0061 0.0623 0.086
Leishmania major hypothetical protein, conserved 0.0061 0.0623 0.0777
Brugia malayi jmjC domain containing protein 0.003 0.0189 0.0211
Entamoeba histolytica hypothetical protein 0.0538 0.7195 0.8936
Trichomonas vaginalis D-aminoacylase, putative 0.0023 0.0096 0.0008
Brugia malayi ephrin receptor 1 precursor 0.0538 0.7195 0.8214
Trichomonas vaginalis leucine-rich transmembrane proteins, putative 0.0061 0.0623 0.0539
Mycobacterium ulcerans aldehyde dehydrogenase 0.0028 0.0168 0.0444
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Loa Loa (eye worm) serine/threonine protein kinase 0.0538 0.7195 0.8215
Loa Loa (eye worm) TK/FER protein kinase 0.0538 0.7195 0.8215
Loa Loa (eye worm) hypothetical protein 0.0061 0.0623 0.0711
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Entamoeba histolytica leucine-rich repeat containing protein 0.0061 0.0623 0.0672
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0088 0.0039
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Entamoeba histolytica tyrosine kinase, putative 0.0538 0.7195 0.8936
Plasmodium falciparum tyrosine kinase-like protein 0.0538 0.7195 1
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Echinococcus multilocularis protein kinase 0.0538 0.7195 1
Schistosoma mansoni serine/threonine RGC 0.0538 0.7195 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0023 0.0089 0.0027
Entamoeba histolytica serine/threonine kinase, putative 0.0538 0.7195 0.8936
Loa Loa (eye worm) TK/ALK protein kinase 0.0538 0.7195 0.8215
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0538 0.7195 1
Echinococcus granulosus leucine rich repeat and death domain containing protein 0.0061 0.0623 0.086
Trichomonas vaginalis podocan, putative 0.0061 0.0623 0.0539
Echinococcus multilocularis phd:f box containing protein 0.003 0.0189 0.0257
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0538 0.7195 1
Echinococcus granulosus leucine rich repeat protein soc 2 0.0061 0.0623 0.086
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0061 0.0623 0.0711
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0088 0.0026
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Plasmodium falciparum tyrosine kinase-like protein 0.0538 0.7195 1
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0538 0.7195 1
Onchocerca volvulus 0.0538 0.7195 0.7194
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Entamoeba histolytica tyrosine kinase, putative 0.0538 0.7195 0.8936
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0061 0.0623 0.0711
Loa Loa (eye worm) hypothetical protein 0.0061 0.0623 0.0711
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0107 0.1246 0.1727
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0088 0.0039
Schistosoma mansoni shoc2 0.0061 0.0623 0.086
Echinococcus multilocularis protein KINase family member (kin 25) 0.0538 0.7195 1
Schistosoma mansoni hypothetical protein 0.0061 0.0623 0.086
Onchocerca volvulus 0.0538 0.7195 0.7194
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0538 0.7195 1
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0538 0.7195 0.8936
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0045 0.0394 0.0445
Echinococcus multilocularis PHD finger protein rhinoceros 0.0063 0.0645 0.0891
Echinococcus multilocularis leucine rich repeat containing protein 0.0061 0.0623 0.086
Echinococcus multilocularis c src tyrosine kinase 0.0538 0.7195 1
Onchocerca volvulus 0.0023 0.0096 0.0092
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Schistosoma mansoni cathepsin D (A01 family) 0.0174 0.2176 0.302
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Schistosoma mansoni inositol monophosphatase 0.0023 0.0088 0.0117
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0059 0.059 0.0743
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0538 0.7195 1
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Echinococcus granulosus protein phosphatase 1 regulatory subunit 7 0.0061 0.0623 0.086
Plasmodium vivax protein phosphatases PP1 regulatory subunit sds22, putative 0.0061 0.0623 0.0788
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Echinococcus multilocularis neuropeptide s receptor 0.0407 0.5395 0.7497
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0538 0.7195 0.8214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0225 0.288 0.2817
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Schistosoma mansoni protein kinase 0.0538 0.7195 1
Echinococcus granulosus Leucine rich repeat typical subtype 0.0061 0.0623 0.086
Trichomonas vaginalis esterase, putative 0.0023 0.0096 0.0008
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Echinococcus granulosus leucine rich repeat protein soc 2 0.0061 0.0623 0.086
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0538 0.7195 0.8215
Loa Loa (eye worm) hypothetical protein 0.0061 0.0623 0.0711
Echinococcus multilocularis tyrosine protein kinase Srms 0.0538 0.7195 1
Loa Loa (eye worm) TK protein kinase 0.0538 0.7195 0.8215
Echinococcus multilocularis epidermal growth factor receptor 0.0538 0.7195 1
Echinococcus multilocularis transfer RNA-Thr 0.0538 0.7195 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0623 0.0711
Trypanosoma cruzi Calcium/calmodulin-dependent protein kinase kinase, putative 0.0061 0.0623 0.0777
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Brugia malayi hypothetical protein 0.0169 0.2111 0.2407
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Loa Loa (eye worm) hypothetical protein 0.0163 0.2028 0.2315
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0538 0.7195 1
Onchocerca volvulus 0.0538 0.7195 0.7194
Echinococcus granulosus ras suppressor protein 1 0.0061 0.0623 0.086
Onchocerca volvulus 0.0061 0.0623 0.0619
Trichomonas vaginalis leucine-rich repeat-containing protein, putative 0.0061 0.0623 0.0539
Leishmania major proteophosphoglycan ppg3, putative 0.0061 0.0623 0.0777
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0061 0.0623 0.0711
Trichomonas vaginalis TK family protein kinase 0.0538 0.7195 0.717
Echinococcus granulosus tyrosine protein kinase csk 0.0538 0.7195 1
Entamoeba histolytica serine/threonine kinase, putative 0.0538 0.7195 0.8936
Trypanosoma brucei protein kinase, putative 0.0538 0.7195 1
Echinococcus granulosus geminin 0.0345 0.4536 0.6302
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0299 0.0213
Echinococcus granulosus tyrosine protein kinase Fyn 0.0538 0.7195 1
Echinococcus multilocularis muscleblind protein 1 0.0163 0.2028 0.2814
Echinococcus granulosus peregrin 0.0065 0.067 0.0926
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0225 0.288 0.3511
Loa Loa (eye worm) jmjC domain-containing protein 0.013 0.1569 0.1792
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Loa Loa (eye worm) TK/FER protein kinase 0.0538 0.7195 0.8215
Trichomonas vaginalis toll, putative 0.0061 0.0623 0.0539
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0061 0.0623 0.0672
Echinococcus granulosus leucine rich repeat containing protein 57 0.0061 0.0623 0.086
Trichomonas vaginalis leucine-rich transmembrane protein, putative 0.0061 0.0623 0.0539
Trichomonas vaginalis protein phosphatase type 2C, putative 0.0061 0.0623 0.0539
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0651 0.8759 1
Schistosoma mansoni protein kinase 0.0538 0.7195 1
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0035 0.0262 0.0359
Giardia lamblia Hypothetical protein 0.0061 0.0623 0.0752
Schistosoma mansoni hypothetical protein 0.0021 0.006 0.0078
Brugia malayi latrophilin 2 splice variant baaae 0.0031 0.0199 0.0222
Entamoeba histolytica hypothetical protein 0.0538 0.7195 0.8936
Mycobacterium tuberculosis Conserved protein 0.0023 0.0096 0.0228
Echinococcus granulosus chromobox protein 1 0.0068 0.0708 0.0979
Loa Loa (eye worm) TK protein kinase 0.0538 0.7195 0.8215
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0035 0.0262 0.0299
Trypanosoma brucei paraflagellar rod component, putative 0.0061 0.0623 0.0788
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0061 0.0623 0.0672
Loa Loa (eye worm) hypothetical protein 0.0061 0.0623 0.0711
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0028 0.0158 0.0214
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0093 0.1065 0.1408
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Echinococcus granulosus activated cdc42 kinase 1 0.0538 0.7195 1
Echinococcus multilocularis JmjC domain containing protein 4 0.003 0.0189 0.0257
Schistosoma mansoni hypothetical protein 0.0538 0.7195 1
Echinococcus multilocularis kinase suppressor of Ras 1 0.0538 0.7195 1
Echinococcus multilocularis receptor type guanylyl cyclase 0.0538 0.7195 1
Leishmania major hypothetical protein, conserved 0.0061 0.0623 0.0777
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0321 0.0293
Echinococcus granulosus protein kinase 0.0538 0.7195 1
Loa Loa (eye worm) glutaminase 0.0153 0.1881 0.2148
Brugia malayi EGF-like domain containing protein 0.0061 0.0623 0.0707
Schistosoma mansoni alpha-glucosidase 0.0153 0.189 0.2622
Echinococcus granulosus leucine rich repeat protein 1 0.0061 0.0623 0.086
Echinococcus granulosus integrin linked protein kinase 0.0538 0.7195 1
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0538 0.7195 1
Echinococcus granulosus leucine rich repeat and fibronectin type III 0.0061 0.0623 0.086
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Onchocerca volvulus 0.0538 0.7195 0.7194
Echinococcus multilocularis tyrosine protein kinase pr2 0.0538 0.7195 1
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0538 0.7195 0.8214
Schistosoma mansoni protein kinase 0.0538 0.7195 1
Trypanosoma brucei protein phosphatase 1, regulatory subunit, putative 0.0061 0.0623 0.0788
Echinococcus granulosus activin receptor type 0.0538 0.7195 1
Trichomonas vaginalis leucine-rich transmembrane protein, putative 0.0061 0.0623 0.0539
Echinococcus multilocularis protein kinase 0.0538 0.7195 1
Brugia malayi PDZ-domain protein scribble 0.0061 0.0623 0.0707
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0538 0.7195 1
Loa Loa (eye worm) protein kinase domain-containing protein 0.0538 0.7195 0.8215
Schistosoma mansoni hypothetical protein 0.0061 0.0623 0.086
Mycobacterium ulcerans aldehyde dehydrogenase 0.0028 0.0168 0.0444
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0538 0.7195 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0538 0.7195 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0623 0.0711
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0321 0.0293
Onchocerca volvulus 0.0538 0.7195 0.7194
Echinococcus granulosus ephrin type A receptor 4 A 0.0538 0.7195 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0045 0.0394 0.045
Loa Loa (eye worm) TK/FER protein kinase 0.0538 0.7195 0.8215
Echinococcus granulosus c src tyrosine kinase 0.0538 0.7195 1
Entamoeba histolytica tyrosine kinase, putative 0.0538 0.7195 0.8936
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0538 0.7195 1
Loa Loa (eye worm) hypothetical protein 0.0538 0.7195 0.8215
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Toxoplasma gondii leucine rich repeat-containing protein 0.0061 0.0623 0.0788
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0059 0.059 0.0815
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0538 0.7195 0.8215
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Loa Loa (eye worm) hypothetical protein 0.0061 0.0623 0.0711
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Schistosoma mansoni cathepsin D (A01 family) 0.0174 0.2176 0.302
Schistosoma mansoni protein kinase 0.0538 0.7195 1
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0538 0.7195 0.8215
Plasmodium vivax protein kinase, putative 0.0538 0.7195 1
Entamoeba histolytica tyrosin kinase, putative 0.0538 0.7195 0.8936
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0088 0.0117
Echinococcus granulosus peroxidasin 0.0061 0.0623 0.086
Trichomonas vaginalis podocan, putative 0.0061 0.0623 0.0539
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.011 0.1293 0.703
Onchocerca volvulus 0.0538 0.7195 0.7194
Loa Loa (eye worm) PDZ-domain-containing protein scribble 0.0061 0.0623 0.0711
Echinococcus multilocularis leucine rich repeat containing protein 47 0.0061 0.0623 0.086
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0088 0.0039
Entamoeba histolytica leucine-rich repeat containing protein 0.0061 0.0623 0.0672
Echinococcus granulosus fibroblast growth factor receptor 4 0.0538 0.7195 1
Loa Loa (eye worm) hypothetical protein 0.0538 0.7195 0.8215
Brugia malayi jmjC domain containing protein 0.003 0.0189 0.0211
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0538 0.7195 1
Echinococcus multilocularis tyrosine protein kinase Blk 0.0538 0.7195 1
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Echinococcus multilocularis Leucine rich repeat domain containing protein 0.0061 0.0623 0.086
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Loa Loa (eye worm) TK protein kinase 0.0538 0.7195 0.8215
Trichomonas vaginalis STE family protein kinase 0.0538 0.7195 0.717
Leishmania major hypothetical protein, conserved 0.0023 0.0096 0.0037
Schistosoma mansoni cellular tumor antigen P53 0.003 0.0194 0.0264
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0339 0.0335
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.0061 0.0623 0.0788
Echinococcus granulosus leucine rich repeat containing protein 0.0061 0.0623 0.086
Brugia malayi Peroxidasin 0.0061 0.0623 0.0707
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0061 0.0623 0.0711
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0044 0.0386 0.053
Loa Loa (eye worm) hypothetical protein 0.0061 0.0623 0.0711
Onchocerca volvulus Slit protein homolog 0.0061 0.0623 0.0619
Echinococcus granulosus PHD finger protein rhinoceros 0.0063 0.0645 0.0891
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0538 0.7195 1
Leishmania major dual specificity protein phosphatase, putative 0.0061 0.0623 0.0777
Brugia malayi hypothetical protein 0.0538 0.7195 0.8214
Brugia malayi SRC-1 0.0538 0.7195 0.8214
Mycobacterium tuberculosis Probable lipase LipE 0.0023 0.0096 0.0228
Brugia malayi Guanylyl cyclase protein 23 0.0538 0.7195 0.8214
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.003 0.0189 0.0168
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0061 0.0623 0.0711
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Trichomonas vaginalis conserved hypothetical protein 0.0538 0.7195 0.717
Entamoeba histolytica serine/threonine kinase, putative 0.0538 0.7195 0.8936
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Echinococcus granulosus Leucine rich repeat domain containing protein 0.0061 0.0623 0.086
Echinococcus multilocularis geminin 0.0345 0.4536 0.6302
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0044 0.0386 0.0436
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0061 0.0623 0.0672
Loa Loa (eye worm) TK/FER protein kinase 0.0538 0.7195 0.8215
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0225 0.288 0.2817
Echinococcus multilocularis Leucine rich repeat domain containing protein 0.0061 0.0623 0.086
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Trichomonas vaginalis protein phosphatase 2C, putative 0.0061 0.0623 0.0539
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0321 0.0235
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0538 0.7195 1
Trypanosoma brucei Flagellum attachment zone protein 20 0.0538 0.7195 1
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Loa Loa (eye worm) TK/ACK protein kinase 0.0538 0.7195 0.8215
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0538 0.7195 1
Trypanosoma cruzi hypothetical protein, conserved 0.0061 0.0623 0.0777
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0538 0.7195 1
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0321 0.0354
Trypanosoma cruzi leucine-rich repeat protein, putative 0.0061 0.0623 0.0777
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0044 0.0386 0.053
Entamoeba histolytica tyrosine kinase, putative 0.0538 0.7195 0.8936
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Echinococcus granulosus tyrosine protein kinase shark 0.0538 0.7195 1
Schistosoma mansoni tyrosine protein kinase 0.0538 0.7195 1
Brugia malayi Protein kinase domain containing protein 0.0061 0.0623 0.0707
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Entamoeba histolytica cysteine surface protein, putative 0.0538 0.7195 0.8936
Loa Loa (eye worm) TK/DDR protein kinase 0.0538 0.7195 0.8215
Echinococcus multilocularis variable lymphocyte receptor 0.0061 0.0623 0.086
Trypanosoma cruzi hypothetical protein, conserved 0.0061 0.0623 0.0777
Loa Loa (eye worm) hypothetical protein 0.0061 0.0623 0.0711
Toxoplasma gondii PHD-finger domain-containing protein 0.0063 0.0645 0.0819
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Schistosoma mansoni glutaminase 0.0153 0.1881 0.261
Onchocerca volvulus 0.0061 0.0623 0.0619
Echinococcus multilocularis leucine rich repeat containing protein 24 0.0061 0.0623 0.086
Trichomonas vaginalis D-aminoacylase, putative 0.0023 0.0096 0.0008
Entamoeba histolytica ankyrin repeat protein 0.0538 0.7195 0.8936
Trichomonas vaginalis set domain proteins, putative 0.0741 1 1
Plasmodium falciparum plasmepsin I 0.0059 0.059 0.0743
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0538 0.7195 0.8936
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0061 0.0623 0.0672
Plasmodium falciparum plasmepsin VI 0.0059 0.059 0.0743
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0096 0.0037
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0538 0.7195 1
Brugia malayi jmjC domain containing protein 0.0114 0.1344 0.1531
Trypanosoma cruzi leucine-rich repeat protein, putative 0.0061 0.0623 0.0777
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0101
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0063 0.0645 0.0891
Schistosoma mansoni protein kinase 0.0538 0.7195 1
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0096 0.005
Echinococcus multilocularis dna polymerase eta 0.0037 0.0284 0.0389
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0061 0.0623 0.0539
Entamoeba histolytica tyrosine kinase, putative 0.0538 0.7195 0.8936
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0538 0.7195 1
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Plasmodium vivax JmjC domain containing protein 0.003 0.0189 0.0181
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0538 0.7195 0.717
Echinococcus multilocularis tyrosine protein kinase HCK 0.0538 0.7195 1
Entamoeba histolytica tyrosin kinase, putative 0.0538 0.7195 0.8936
Echinococcus multilocularis leucine rich repeat protein SHOC 2 0.0061 0.0623 0.086
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Schistosoma mansoni hypothetical protein 0.0345 0.4536 0.6302
Onchocerca volvulus 0.0061 0.0623 0.0619
Loa Loa (eye worm) TK/FER protein kinase 0.0538 0.7195 0.8215
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0538 0.7195 1
Echinococcus multilocularis leucine rich repeat and calponin y 0.0061 0.0623 0.086
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0096 0.005
Echinococcus multilocularis tyrosine protein kinase shark 0.0538 0.7195 1
Brugia malayi protein-tyrosine kinase 0.0538 0.7195 0.8214
Schistosoma mansoni hypothetical protein 0.0061 0.0623 0.086
Trichomonas vaginalis chaoptin, putative 0.0061 0.0623 0.0539
Loa Loa (eye worm) hypothetical protein 0.0061 0.0623 0.0711
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0538 0.7195 1
Entamoeba histolytica tyrosine kinase, putative 0.0538 0.7195 0.8936
Entamoeba histolytica receptor protein kinase, putative 0.0538 0.7195 0.8936
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0088 0.0117
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0538 0.7195 1
Brugia malayi Bromodomain containing protein 0.0058 0.0573 0.065
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Echinococcus granulosus survival motor neuron protein 1 0.0255 0.3295 0.4576
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0538 0.7195 1
Loa Loa (eye worm) intermediate filament protein 0.0016 0.0004 0.0005
Echinococcus multilocularis lysine specific demethylase 5A 0.0112 0.1324 0.1835
Echinococcus granulosus kinase suppressor of Ras 1 0.0538 0.7195 1
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0044 0.0386 0.053
Plasmodium vivax hypothetical protein, conserved 0.0063 0.0645 0.0819
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0599 0.8042 1
Loa Loa (eye worm) TK/FER protein kinase 0.0538 0.7195 0.8215
Echinococcus multilocularis inositol monophosphatase 1 0.0023 0.0088 0.0117
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0538 0.7195 0.8936
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Giardia lamblia Leucine-rich repeat protein 0.0061 0.0623 0.0752
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.0061 0.0623 0.0788
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0061 0.0623 0.0711
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.1018 0.1409
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0225 0.288 0.2817
Loa Loa (eye worm) TK/EPH protein kinase 0.0538 0.7195 0.8215
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0708 0.0809
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Loa Loa (eye worm) hypothetical protein 0.0538 0.7195 0.8215
Treponema pallidum fructose-bisphosphate aldolase 0.0225 0.288 0.5
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0538 0.7195 0.717
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.011 0.1293 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0538 0.7195 1
Trypanosoma brucei unspecified product 0.0023 0.0088 0.0039
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Echinococcus granulosus beta LACTamase domain containing family member 0.0023 0.0096 0.0127
Mycobacterium tuberculosis Conserved protein 0.0023 0.0096 0.0228
Echinococcus granulosus protein tyrosine kinase 0.0538 0.7195 1
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0623 0.0539
Onchocerca volvulus 0.0061 0.0623 0.0619
Schistosoma mansoni alpha glucosidase 0.0039 0.0321 0.0441
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0088 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0623 0.0539
Echinococcus granulosus leucine rich repeat containing protein 47 0.0061 0.0623 0.086
Brugia malayi Immunoglobulin I-set domain containing protein 0.0061 0.0623 0.0707
Brugia malayi hypothetical protein 0.0538 0.7195 0.8214
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0035 0.0262 0.0359
Echinococcus multilocularis tyrosine protein kinase csk 0.0538 0.7195 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0035 0.0262 0.0295
Loa Loa (eye worm) hypothetical protein 0.0538 0.7195 0.8215
Entamoeba histolytica tyrosin kinase, putative 0.0538 0.7195 0.8936
Echinococcus multilocularis cell polarity protein leucine rich repeat 0.0061 0.0623 0.086
Entamoeba histolytica DnaJ family protein 0.0061 0.0623 0.0672
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Loa Loa (eye worm) hypothetical protein 0.0061 0.0623 0.0711
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0028 0.0168 0.0138
Plasmodium vivax tyrosine kinase-like protein, putative 0.0538 0.7195 1
Loa Loa (eye worm) TK/ABL protein kinase 0.0538 0.7195 0.8215
Trichomonas vaginalis toll, putative 0.0061 0.0623 0.0539
Echinococcus granulosus chromobox protein 1 0.0068 0.0708 0.0979
Loa Loa (eye worm) TK protein kinase 0.0538 0.7195 0.8215
Echinococcus granulosus leucine rich repeat containing protein 15 0.0061 0.0623 0.086
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0061 0.0623 0.0539
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0708 0.0626
Brugia malayi Tyrosine-protein kinase PR2 0.0538 0.7195 0.8214
Echinococcus granulosus histone lysine methyltransferase setb 0.0107 0.1246 0.1727
Schistosoma mansoni slit 0.0061 0.0623 0.086
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0538 0.7195 1
Plasmodium vivax SET domain protein, putative 0.0093 0.1065 0.1408
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0023 0.0096 0.0109
Echinococcus multilocularis protein tyrosine kinase 0.0538 0.7195 1
Plasmodium vivax plasmepsin IV, putative 0.0059 0.059 0.0743
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Trichomonas vaginalis leucine-rich transmembrane proteins, putative 0.0061 0.0623 0.0539
Leishmania major DNA polymerase eta, putative 0.0037 0.0284 0.0301
Schistosoma mansoni protein kinase 0.0538 0.7195 1
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Brugia malayi beta-lactamase 0.0023 0.0096 0.0105
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Mycobacterium leprae Probable lipase LipE 0.0023 0.0096 0.0324
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0538 0.7195 0.8936
Echinococcus granulosus leucine rich repeat containing protein 70 0.0061 0.0623 0.086
Trypanosoma brucei Pseudokinase, putative 0.0538 0.7195 1
Trypanosoma cruzi protein kinase, putative 0.0538 0.7195 1
Loa Loa (eye worm) TK/ROR protein kinase 0.0538 0.7195 0.8215
Schistosoma mansoni survival motor neuron protein 0.0052 0.0494 0.0682
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0538 0.7195 0.8215
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0061 0.0623 0.086
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0538 0.7195 0.8936
Entamoeba histolytica tyrosine kinase, putative 0.0538 0.7195 0.8936
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0225 0.288 0.2817
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0538 0.7195 1
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0538 0.7195 1
Echinococcus granulosus DEAD box ATP dependent RNA helicase 0.0061 0.0623 0.086
Onchocerca volvulus 0.0538 0.7195 0.7194
Loa Loa (eye worm) hypothetical protein 0.0538 0.7195 0.8215
Echinococcus multilocularis integrin linked protein kinase 0.0538 0.7195 1
Echinococcus granulosus jumonji domain containing 1A 0.003 0.0189 0.0257
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0538 0.7195 1
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0321 0.0366
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Toxoplasma gondii aldehyde dehydrogenase 0.0028 0.0168 0.015
Schistosoma mansoni hypothetical protein 0.0061 0.0623 0.086
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0088 0.0039
Plasmodium falciparum protein kinase, putative 0.0538 0.7195 1
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Echinococcus granulosus leucine rich repeat 0.0061 0.0623 0.086
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.003 0.0189 0.0181
Schistosoma mansoni hypothetical protein 0.0061 0.0623 0.086
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0044 0.0386 0.1875
Trypanosoma brucei PAB1-binding protein , putative 0.0023 0.0089 0.004
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0044 0.0386 0.166
Schistosoma mansoni alpha-glucosidase 0.0153 0.189 0.2622
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.0061 0.0623 0.0788
Brugia malayi ras-binding protein SUR-8 0.0061 0.0623 0.0707
Mycobacterium ulcerans lipase LipD 0.0023 0.0096 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0088 0.0039
Onchocerca volvulus 1D304 homolog 0.0061 0.0623 0.0619
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0061 0.0623 0.0672
Toxoplasma gondii leucine rich repeat-containing protein 0.0061 0.0623 0.0788
Echinococcus multilocularis survival motor neuron protein 1 0.0255 0.3295 0.4576
Loa Loa (eye worm) TK/FER protein kinase 0.0538 0.7195 0.8215
Entamoeba histolytica serine/threonine kinase, putative 0.0538 0.7195 0.8936
Echinococcus multilocularis leucine rich repeat and death domain containing protein 0.0061 0.0623 0.086
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0538 0.7195 1
Trypanosoma brucei dual specificity protein phosphatase, putative 0.0061 0.0623 0.0788
Loa Loa (eye worm) TK/EGFR protein kinase 0.0538 0.7195 0.8215
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Brugia malayi Leucine Rich Repeat family protein 0.0061 0.0623 0.0707
Leishmania major hypothetical protein, conserved 0.0061 0.0623 0.0777
Mycobacterium tuberculosis Conserved protein 0.0023 0.0096 0.0228
Trichomonas vaginalis leucine-rich repeat-containing protein, putative 0.0061 0.0623 0.0539
Loa Loa (eye worm) TK protein kinase 0.0538 0.7195 0.8215
Entamoeba histolytica tyrosine kinase, putative 0.0538 0.7195 0.8936
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0538 0.7195 0.8215
Echinococcus multilocularis tyrosine protein kinase 0.0538 0.7195 1
Trichomonas vaginalis conserved hypothetical protein 0.0538 0.7195 0.717
Onchocerca volvulus 0.0052 0.0494 0.049
Schistosoma mansoni serine/threonine protein kinase 0.0538 0.7195 1
Loa Loa (eye worm) TK protein kinase 0.0538 0.7195 0.8215
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0538 0.7195 0.7194
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0044 0.0386 0.166
Plasmodium falciparum plasmepsin IV 0.0059 0.059 0.0743
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0538 0.7195 0.7194
Schistosoma mansoni phosphatidylserine receptor 0.003 0.0189 0.0257
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0538 0.7195 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0035 0.0262 0.0359
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0538 0.7195 1
Trichomonas vaginalis leucine-rich repeat containing protein, putative 0.0061 0.0623 0.0539
Trichomonas vaginalis conserved hypothetical protein 0.0538 0.7195 0.717
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0538 0.7195 0.8214
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Loa Loa (eye worm) hypothetical protein 0.0538 0.7195 0.8215
Loa Loa (eye worm) hypothetical protein 0.0538 0.7195 0.8215
Echinococcus granulosus tyrosine kinase 0.0538 0.7195 1
Trichomonas vaginalis conserved hypothetical protein 0.0538 0.7195 0.717
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0538 0.7195 1
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0299 0.0213
Brugia malayi jmjC domain containing protein 0.003 0.0189 0.0211
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0046 0.0411 0.0565
Brugia malayi hypothetical protein 0.0061 0.0623 0.0707
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0538 0.7195 0.8936
Loa Loa (eye worm) hypothetical protein 0.003 0.0194 0.0221
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0088 0.0026
Echinococcus granulosus tyrosine protein kinase Lyn 0.0538 0.7195 1
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0321 0.0354
Echinococcus multilocularis jumonji domain containing 1A 0.003 0.0189 0.0257
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0538 0.7195 1
Loa Loa (eye worm) hypothetical protein 0.0118 0.1398 0.1596
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Loa Loa (eye worm) hypothetical protein 0.003 0.0184 0.021
Onchocerca volvulus Tyrosine kinase homolog 0.0538 0.7195 0.7194
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0059 0.059 0.0674
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0299 0.0295
Trypanosoma brucei kinatase, putative 0.0061 0.0623 0.0788
Entamoeba histolytica hypothetical protein 0.0538 0.7195 0.8936
Echinococcus multilocularis tyrosine protein kinase csk 0.0538 0.7195 1
Echinococcus granulosus dna polymerase eta 0.0037 0.0284 0.0389
Onchocerca volvulus 0.003 0.0186 0.0182
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0044 0.0386 0.0444
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0061 0.0623 0.0711
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0538 0.7195 1
Giardia lamblia Protein 21.1 0.0538 0.7195 1
Trichomonas vaginalis protein phosphatases pp1 regulatory subunit, putative 0.0061 0.0623 0.0539
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0041 0.0345 0.0393
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Brugia malayi hypothetical protein 0.0023 0.0089 0.0097
Echinococcus granulosus slit 2 protein 0.0061 0.0623 0.086
Trichomonas vaginalis conserved hypothetical protein 0.0538 0.7195 0.717
Schistosoma mansoni protein kinase 0.0538 0.7195 1
Entamoeba histolytica tyrosine kinase, putative 0.0538 0.7195 0.8936
Echinococcus multilocularis leucine rich repeat containing protein 70 0.0061 0.0623 0.086
Mycobacterium ulcerans hypothetical protein 0.0023 0.0096 0.0043
Loa Loa (eye worm) hypothetical protein 0.0031 0.0209 0.0239
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0046 0.0411 0.0565
Brugia malayi jmjC domain containing protein 0.003 0.0189 0.0211
Echinococcus granulosus tyrosine protein kinase 0.0538 0.7195 1
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0538 0.7195 1
Loa Loa (eye worm) hypothetical protein 0.0538 0.7195 0.8215
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0088 0.0117
Brugia malayi ras suppressor protein 1 0.0061 0.0623 0.0707
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0023 0.0096 0.0127
Loa Loa (eye worm) hypothetical protein 0.0023 0.0096 0.0109
Brugia malayi chromobox protein homolog 3 0.0038 0.0299 0.0337
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Echinococcus multilocularis tyrosine kinase 0.0538 0.7195 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0045 0.0394 0.0445
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0088 0.0096
Echinococcus multilocularis tyrosine protein kinase csk 0.0538 0.7195 1
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0189 0.0216
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0108 0.0144
Echinococcus multilocularis activated cdc42 kinase 1 0.0538 0.7195 1
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Schistosoma mansoni ephrin receptor 0.0538 0.7195 1
Loa Loa (eye worm) TK/INSR protein kinase 0.0538 0.7195 0.8215
Entamoeba histolytica leucine-rich repeat containing protein 0.0061 0.0623 0.0672
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0623 0.0539
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0061 0.0623 0.0711
Trypanosoma brucei leucine-rich repeat protein (LRRP), putative 0.0061 0.0623 0.0788
Echinococcus granulosus raf serine:threonine protein kinase 0.0538 0.7195 1
Echinococcus granulosus phd:f box containing protein 0.003 0.0189 0.0257
Trichomonas vaginalis protein phosphatase 2C delta isoform, putative 0.0061 0.0623 0.0539
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0061 0.0623 0.0711
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Loa Loa (eye worm) leucine Rich Repeat family protein 0.0061 0.0623 0.0711
Entamoeba histolytica leucine rich repeat / protein phosphatase 2C domain containing protein 0.0061 0.0623 0.0672
Loa Loa (eye worm) hypothetical protein 0.0023 0.0096 0.0109
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0538 0.7195 1
Brugia malayi SH2 domain containing protein 0.0538 0.7195 0.8214
Echinococcus multilocularis muscleblind protein 0.0163 0.2028 0.2814
Toxoplasma gondii STE kinase 0.0538 0.7195 1
Brugia malayi SH2 domain containing protein 0.0538 0.7195 0.8214
Echinococcus granulosus tyrosine protein kinase csk 0.0538 0.7195 1
Loa Loa (eye worm) beta-lactamase 0.0023 0.0096 0.0109
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Loa Loa (eye worm) TK/FER protein kinase 0.0538 0.7195 0.8215
Echinococcus multilocularis leucine rich repeat and fibronectin type III 0.0061 0.0623 0.086
Loa Loa (eye worm) hypothetical protein 0.0031 0.0199 0.0227
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.011 0.1293 0.6719
Onchocerca volvulus 0.0061 0.0623 0.0619
Entamoeba histolytica tyrosine kinase, putative 0.0538 0.7195 0.8936
Entamoeba histolytica hypothetical protein 0.0538 0.7195 0.8936
Brugia malayi Furin-like cysteine rich region family protein 0.0538 0.7195 0.8214
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0023 0.0088 0.0039
Echinococcus multilocularis chromobox protein 1 0.0068 0.0708 0.0979
Trichomonas vaginalis TKL family protein kinase 0.0538 0.7195 0.717
Brugia malayi PHD-finger family protein 0.0019 0.0041 0.0042
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0107 0.1246 0.1727
Schistosoma mansoni peroxidasin 0.0061 0.0623 0.086
Echinococcus multilocularis beta LACTamase domain containing family member 0.0023 0.0096 0.0127
Trypanosoma cruzi protein phosphatase 1, regulatory subunit, putative 0.0061 0.0623 0.0777
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Echinococcus multilocularis FL cytokine receptor 0.0538 0.7195 1
Onchocerca volvulus 0.0538 0.7195 0.7194
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0088 0.0027
Schistosoma mansoni hypothetical protein 0.0061 0.0623 0.086
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0538 0.7195 1
Onchocerca volvulus 0.003 0.0194 0.019
Plasmodium falciparum phd finger protein, putative 0.0063 0.0645 0.0819
Plasmodium falciparum protein kinase, putative 0.0538 0.7195 1
Loa Loa (eye worm) TK/FER protein kinase 0.0538 0.7195 0.8215
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0538 0.7195 1
Loa Loa (eye worm) TK/CSK protein kinase 0.0538 0.7195 0.8215
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0538 0.7195 0.8214
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0321 0.0441
Entamoeba histolytica protein kinase, putative 0.0538 0.7195 0.8936
Entamoeba histolytica tyrosine kinase, putative 0.0538 0.7195 0.8936
Schistosoma mansoni aldehyde dehydrogenase 0.0028 0.0168 0.0227
Toxoplasma gondii protein kinase 0.0538 0.7195 1
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Echinococcus granulosus retinal guanylyl cyclase 2 0.0538 0.7195 1
Schistosoma mansoni protein tyrosine kinase 0.0538 0.7195 1
Echinococcus granulosus fetal alzheimer antigen falz 0.0017 0.0016 0.0016
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0538 0.7195 1
Echinococcus multilocularis DEAD box ATP dependent RNA helicase 0.0061 0.0623 0.086
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0061 0.0623 0.0711
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0005
Echinococcus multilocularis leucine rich repeat containing protein 23 0.0061 0.0623 0.086
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Echinococcus multilocularis activin receptor type 0.0538 0.7195 1
Brugia malayi integrin-linked kinase 0.0538 0.7195 0.8214
Entamoeba histolytica protein kinase domain containing protein 0.0538 0.7195 0.8936
Loa Loa (eye worm) hypothetical protein 0.0033 0.0229 0.0262
Schistosoma mansoni aldehyde dehydrogenase 0.0028 0.0168 0.0227
Schistosoma mansoni tyrosine kinase 0.0538 0.7195 1
Onchocerca volvulus 0.0538 0.7195 0.7194
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0225 0.288 0.2817
Brugia malayi Tyrosine-protein kinase abl-1 0.0538 0.7195 0.8214
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0538 0.7195 0.8936
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0538 0.7195 1
Echinococcus multilocularis tyrosine protein kinase Abl 0.0538 0.7195 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0538 0.7195 0.8936
Schistosoma mansoni chromobox protein 0.0068 0.0708 0.0979
Echinococcus granulosus tyrosine protein kinase pr2 0.0538 0.7195 1
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0321 0.0354
Echinococcus granulosus lysine specific demethylase 5A 0.0114 0.1344 0.1863
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0088 0.0039
Loa Loa (eye worm) hypothetical protein 0.0054 0.0528 0.0602
Echinococcus granulosus leucine rich repeat neuronal protein 0.0061 0.0623 0.086
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0225 0.288 0.2817
Schistosoma mansoni jumonji domain containing protein 0.02 0.2532 0.3516
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0538 0.7195 0.717
Onchocerca volvulus 0.0061 0.0623 0.0619
Schistosoma mansoni serine/threonine protein kinase 0.0538 0.7195 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0284 0.0324
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0031 0.0209 0.0286
Loa Loa (eye worm) RGC/RGC protein kinase 0.0538 0.7195 0.8215
Loa Loa (eye worm) hypothetical protein 0.0538 0.7195 0.8215
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0321 0.0235
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0059 0.059 0.0815
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0538 0.7195 0.8936
Echinococcus granulosus tyrosine protein kinase Blk 0.0538 0.7195 1
Loa Loa (eye worm) TK/FER protein kinase 0.0538 0.7195 0.8215
Loa Loa (eye worm) PHD-finger family protein 0.0063 0.0645 0.0736
Giardia lamblia Kinase, NEK 0.0538 0.7195 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0299 0.0341
Echinococcus granulosus tyrosine protein kinase csk 0.0538 0.7195 1
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0064 0.0663 0.0757
Giardia lamblia Fructose-bisphosphate aldolase 0.0225 0.288 0.3929
Brugia malayi Protein kinase domain containing protein 0.0538 0.7195 0.8214
Echinococcus granulosus protein flightless 1 0.0061 0.0623 0.086

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 25 nM Inhibition of human renin ChEMBL. 3312604
Inhibition (binding) = 61 % Compound was evaluated for percent inhibition of renin at a concentration of 2.5*10e-8 M at 60 min preincubation time ChEMBL. 3312604
Inhibition (binding) = 66 % Compound was evaluated for percent inhibition of renin at a concentration of 2.5*10e-8 M at 5 min preincubation time ChEMBL. 3312604

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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