Detailed information for compound 220343

Basic information

Technical information
  • TDR Targets ID: 220343
  • Name: 4-[2-[1-(benzenesulfonyl)-5-methoxyindol-3-yl ]ethyl]morpholine
  • MW: 400.491 | Formula: C21H24N2O4S
  • H donors: 0 H acceptors: 2 LogP: 3.12 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc2c(c1)c(CCN1CCOCC1)cn2S(=O)(=O)c1ccccc1
  • InChi: 1S/C21H24N2O4S/c1-26-18-7-8-21-20(15-18)17(9-10-22-11-13-27-14-12-22)16-23(21)28(24,25)19-5-3-2-4-6-19/h2-8,15-16H,9-14H2,1H3
  • InChiKey: BNEKZVNOMCFDII-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 4-[2-[1-(benzenesulfonyl)-5-methoxy-indol-3-yl]ethyl]morpholine
  • 4-[2-[1-(benzenesulfonyl)-5-methoxy-3-indolyl]ethyl]morpholine
  • 4-[2-[5-methoxy-1-(phenylsulfonyl)indol-3-yl]ethyl]morpholine
  • 4-[2-(1-besyl-5-methoxy-indol-3-yl)ethyl]morpholine
  • 5-methoxy-3-(2-morpholin-4-ylethyl)-1-phenylsulfonylindole
  • 5-methoxy-3-(2-morpholinoethyl)-1-phenylsulfonyl-indole
  • 5-methoxy-3-(2-morpholinoethyl)-1-phenylsulfonylindole
  • 5-methoxy-3-(2-morpholin-4-ylethyl)-1-phenylsulfonyl-indole

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus tm gpcr rhodopsin Get druggable targets OG5_145685 All targets in OG5_145685
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily Get druggable targets OG5_145685 All targets in OG5_145685
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni trans-prenyltransferase 0.0792 0.0449 0.2516
Brugia malayi GnHR receptor homolog 0.0341 0.0185 0.1034
Loa Loa (eye worm) matrix metalloproteinase 0.0075 0.0029 0.0161
Brugia malayi Polyprenyl synthetase family protein 0.3072 0.1785 1
Mycobacterium tuberculosis Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) 0.0111 0.005 0.0099
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0059 0.002 0.0109
Loa Loa (eye worm) hypothetical protein 0.0404 0.0221 0.124
Echinococcus multilocularis serotonin receptor 0.0341 0.0185 0.1034
Echinococcus multilocularis lamin 0.0055 0.0017 0.0097
Onchocerca volvulus 0.0055 0.0017 0.0568
Schistosoma mansoni neuropeptide F-like receptor 0.0341 0.0185 0.1034
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0176 0.0088 0.0494
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0031 0.0003 0.0003
Schistosoma mansoni amine GPCR 0.0341 0.0185 0.1034
Echinococcus granulosus microtubule associated protein 2 0.1052 0.0602 0.337
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.0025 0.0141
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0439 0.0242 0.1355
Brugia malayi Matrixin family protein 0.0075 0.0029 0.016
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0341 0.0185 0.1034
Entamoeba histolytica phosphofructokinase, putative 0.0072 0.0027 0.0162
Echinococcus multilocularis neuropeptides capa receptor 0.0341 0.0185 0.1034
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0088 0.0037 0.0204
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0341 0.0185 0.1034
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0341 0.0185 0.1034
Echinococcus multilocularis neuropeptide s receptor 0.0819 0.0465 0.2602
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0089 0.0037 0.0207
Echinococcus multilocularis microtubule associated protein 2 0.1052 0.0602 0.337
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0792 0.0449 0.0434
Echinococcus granulosus dna polymerase eta 0.004 0.0009 0.0048
Echinococcus granulosus rhodopsin orphan GPCR 0.0341 0.0185 0.1034
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Schistosoma mansoni hypothetical protein 0.0341 0.0185 0.1034
Echinococcus multilocularis dna polymerase eta 0.004 0.0009 0.0048
Toxoplasma gondii aspartyl protease ASP3 0.0038 0.0007 0.0007
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0176 0.0088 0.0494
Brugia malayi Adenine phosphoribosyltransferase 0.0103 0.0045 0.0252
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0404 0.0221 0.4687
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0228 0.0118 0.0663
Loa Loa (eye worm) hypothetical protein 0.0054 0.0017 0.0094
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0009 0.0048
Brugia malayi Guanylyl cyclase protein 23 0.0134 0.0063 0.0353
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0088 0.0037 0.0204
Trypanosoma brucei aminopeptidase, putative 0.0031 0.0003 0.0018
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.3072 0.1785 0.1785
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0115 0.0052 0.0292
Leishmania major folylpolyglutamate synthetase 0.0173 0.0087 0.0484
Trypanosoma brucei endonuclease G, putative 0.0053 0.0016 0.0089
Brugia malayi aspartic protease BmAsp-2, identical 0.0038 0.0007 0.004
Toxoplasma gondii aldehyde dehydrogenase 0.0056 0.0018 0.0017
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0089 0.0037 0.0207
Toxoplasma gondii thioredoxin reductase 0.0032 0.0004 0.0003
Loa Loa (eye worm) aspartic protease BmAsp-2 0.016 0.0079 0.0442
Echinococcus granulosus rhodopsin orphan GPCR 0.0341 0.0185 0.1034
Echinococcus multilocularis g-protein coupled receptor 0.0341 0.0185 0.1034
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0115 0.0052 0.0292
Schistosoma mansoni endonuclease related 0.0053 0.0016 0.0089
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.7089 1 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0003 0.0018
Trypanosoma cruzi aminopeptidase, putative 0.0089 0.0037 0.0207
Brugia malayi Receptor family ligand binding region containing protein 0.0311 0.0167 0.0935
Trichomonas vaginalis glutaminase, putative 0.0284 0.0151 0.0847
Plasmodium falciparum orotate phosphoribosyltransferase 0.0103 0.0045 0.0045
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0088 0.0037 0.0204
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0038 0.0007 0.0007
Loa Loa (eye worm) dihydrofolate reductase 0.0178 0.009 0.0501
Brugia malayi intermediate filament protein 0.0055 0.0017 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0016 0.0089
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0007 0.004
Schistosoma mansoni histamine h1 receptor 0.0341 0.0185 0.1034
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0068 0.0025 0.0025
Plasmodium vivax hypoxanthine-guanine phosphoribosyltransferase, putative 0.0439 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0177 0.0089 0.0498
Echinococcus granulosus glutamate receptor NMDA 0.0053 0.0016 0.0087
Loa Loa (eye worm) hypothetical protein 0.0134 0.0063 0.0354
Entamoeba histolytica phosphofructokinase, putative 0.0072 0.0027 0.0162
Echinococcus multilocularis n acetylated alpha linked acidic dipeptidase 2 0.014 0.0067 0.0374
Echinococcus multilocularis glutamate receptor 2 0.0282 0.015 0.0842
Trypanosoma cruzi hypothetical protein, conserved 0.0115 0.0052 0.0292
Leishmania major ATP-dependent phosphofructokinase 0.0072 0.0027 0.0153
Schistosoma mansoni memapsin-2 (A01 family) 0.0038 0.0007 0.004
Brugia malayi metabotropic glutamate receptor type 2 0.0547 0.0305 0.1709
Brugia malayi follicle stimulating hormone receptor 0.0552 0.0308 0.1727
Mycobacterium tuberculosis Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (imp pyrophosphor 0.0336 0.0182 0.0364
Brugia malayi hypothetical protein 0.0038 0.0007 0.004
Echinococcus multilocularis neuropeptide receptor A26 0.0819 0.0465 0.2602
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0122 0.0056 0.0056
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.0025 0.0141
Toxoplasma gondii endonuclease IV APN 0.0122 0.0056 0.0056
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0115 0.0052 0.0293
Mycobacterium tuberculosis Probable reductase 0.0073 0.0027 0.0055
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0036 0.0006 0.0033
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.001 0.0054
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Schistosoma mansoni hypothetical protein 0.0077 0.003 0.0167
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0017 0.0097
Brugia malayi peptidase family M13 containing protein 0.0029 0.0002 0.0009
Mycobacterium ulcerans folylpolyglutamate synthase protein FolC 0.0173 0.0087 0.0086
Onchocerca volvulus Matrix metalloproteinase homolog 0.0166 0.0082 0.2694
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0077 0.003 0.0166
Plasmodium falciparum glutathione reductase 0.0032 0.0004 0.0003
Brugia malayi Glutamate receptor 1 precursor 0.0149 0.0072 0.0404
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0031 0.0003 0.0018
Onchocerca volvulus Matrilysin homolog 0.0166 0.0082 0.2694
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.0025 0.0141
Loa Loa (eye worm) glutamate receptor 1 0.0149 0.0072 0.0404
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0053 0.0016 0.0089
Mycobacterium ulcerans phytoene synthase, CrtB 0.0093 0.0039 0.0039
Echinococcus multilocularis Squalene phytoene synthase 0.0093 0.0039 0.022
Onchocerca volvulus 0.0341 0.0185 0.6066
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0341 0.0185 0.1035
Echinococcus multilocularis purine nucleoside phosphorylase 0.005 0.0014 0.008
Loa Loa (eye worm) hypothetical protein 0.0089 0.0037 0.0206
Mycobacterium tuberculosis Conserved protein 0.0103 0.0045 0.009
Onchocerca volvulus 0.0341 0.0185 0.6066
Echinococcus granulosus biogenic amine 5HT receptor 0.0341 0.0185 0.1034
Echinococcus granulosus nmda type glutamate receptor 0.0232 0.0121 0.0678
Schistosoma mansoni folylpolyglutamate synthase 0.0173 0.0087 0.0484
Brugia malayi hypothetical protein 0.0089 0.0037 0.0207
Echinococcus multilocularis dihydrofolate reductase 0.0178 0.009 0.0501
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0068 0.0025 0.0139
Loa Loa (eye worm) hypothetical protein 0.0086 0.0035 0.0197
Brugia malayi hypothetical protein 0.0093 0.0039 0.022
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Loa Loa (eye worm) hypothetical protein 0.0117 0.0054 0.03
Loa Loa (eye worm) hypothetical protein 0.0026 0 0.0001
Brugia malayi aspartic protease BmAsp-1, identical 0.0038 0.0007 0.004
Brugia malayi Probable ClpP-like protease 0.0079 0.0031 0.0173
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0063 0.0022 0.0723
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.001 0.0054
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0072 0.0027 0.0027
Echinococcus multilocularis hypoxanthine guanine phosphoribosyltransferase 0.0439 0.0242 0.1355
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0061 0.002 0.0114
Loa Loa (eye worm) hypothetical protein 0.0058 0.0019 0.0105
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.7089 1 1
Onchocerca volvulus 0.0115 0.0052 0.1712
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0031 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0177 0.0089 0.0497
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0115 0.0052 0.0293
Mycobacterium ulcerans 6-phosphofructokinase 0.0072 0.0027 0.0027
Trypanosoma cruzi Peptide deformylase 2, putative 0.0042 0.001 0.0054
Echinococcus granulosus neuropeptide Y receptor 0.0341 0.0185 0.1034
Leishmania major farnesyl pyrophosphate synthase 0.3072 0.1785 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0341 0.0185 0.1034
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0169 0.0084 0.0468
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0 0.0001
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0058 0.0019 0.0104
Echinococcus granulosus glutamate receptor 2 0.0282 0.015 0.0842
Loa Loa (eye worm) hypothetical protein 0.0058 0.0019 0.0106
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0053 0.0016 0.0089
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0089 0.0037 0.0207
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0053 0.0016 0.0089
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0115 0.0052 0.0293
Schistosoma mansoni tyrosine kinase 0.0134 0.0063 0.0353
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0031 0.0003 0.0015
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.018 0.009 0.0506
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0007 0.0038
Schistosoma mansoni purine nucleoside phosphorylase 0.0063 0.0022 0.0123
Echinococcus granulosus receptor type guanylyl cyclase 0.0134 0.0063 0.0353
Loa Loa (eye worm) hypothetical protein 0.0089 0.0037 0.0206
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.0828 0.047 0.047
Loa Loa (eye worm) hypothetical protein 0.0026 0 0.0002
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0566 0.0316 0.1773
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.001 0.0054
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0282 0.015 0.0842
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0061 0.002 0.0114
Trypanosoma cruzi endonuclease G, putative 0.0053 0.0016 0.0089
Plasmodium falciparum plasmepsin VII 0.0038 0.0007 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0341 0.0185 0.1034
Loa Loa (eye worm) hypothetical protein 0.0027 0.0001 0.0003
Brugia malayi G-protein coupled receptor 0.0341 0.0185 0.1034
Mycobacterium tuberculosis Adenine phosphoribosyltransferase Apt (APRT) (AMP diphosphorylase) (AMP pyrophosphorylase) (transphosphoribosidase) 0.0103 0.0045 0.009
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0032 0.0004 0.0119
Schistosoma mansoni 6-phosphofructokinase 0.0072 0.0027 0.0153
Loa Loa (eye worm) hypothetical protein 0.0089 0.0037 0.0206
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0341 0.0185 0.1034
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.3072 0.1785 1
Mycobacterium ulcerans peptide deformylase 0.0111 0.005 0.005
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0077 0.003 0.0166
Loa Loa (eye worm) hypothetical protein 0.0031 0.0003 0.0018
Loa Loa (eye worm) hypothetical protein 0.0079 0.0031 0.0174
Trypanosoma brucei squalene synthase, putative 0.0298 0.016 0.0895
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.3072 0.1785 0.1785
Onchocerca volvulus 0.0031 0.0003 0.0103
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0792 0.0449 0.2516
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0081 0.0032 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.001 0.0054
Echinococcus multilocularis uridine 5' monophosphate synthase 0.0103 0.0045 0.0252
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Giardia lamblia Farnesyl diphosphate synthase 0.3072 0.1785 1
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0063 0.0022 0.0123
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0792 0.0449 0.2516
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0103 0.0045 0.0252
Toxoplasma gondii MRP family domain-containing protein 0.0026 0 0.0000019522
Loa Loa (eye worm) hypothetical protein 0.0134 0.0063 0.0354
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0827 0.047 0.2631
Plasmodium falciparum hypoxanthine-guanine phosphoribosyltransferase 0.0439 0.0242 0.0242
Echinococcus multilocularis folylpolyglutamate synthase, mitochondrial 0.0173 0.0087 0.0484
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0246 0.0129 0.0722
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0068 0.0025 0.0025
Echinococcus multilocularis g protein coupled receptor 0.0341 0.0185 0.1034
Echinococcus multilocularis g protein coupled receptor 0.0341 0.0185 0.1034
Schistosoma mansoni endothelin-converting enzyme-related 0.0029 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0026 0 0.0001
Schistosoma mansoni protein kinase 0.0134 0.0063 0.0353
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.7089 1 1
Plasmodium falciparum plasmepsin X 0.0038 0.0007 0.0007
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0084 0.0034 0.019
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0053 0.0016 0.0089
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 1.7089 1 1
Loa Loa (eye worm) peptidase family M1 containing protein 0.0244 0.0128 0.0718
Mycobacterium ulcerans hypothetical protein 0.0103 0.0045 0.0045
Echinococcus granulosus hypoxanthine guanine phosphoribosyltransferase 0.0439 0.0242 0.1355
Echinococcus multilocularis rhodopsin orphan GPCR 0.0341 0.0185 0.1034
Treponema pallidum octaprenyl-diphosphate synthase 0.0827 0.047 0.0469
Trypanosoma cruzi hypothetical protein, conserved 0.0115 0.0052 0.0292
Plasmodium vivax plasmepsin V, putative 0.0038 0.0007 0.0007
Trypanosoma cruzi phytoene synthase, putative 0.0093 0.0039 0.022
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0176 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.1305 0.075 0.42
Trypanosoma brucei orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0103 0.0045 0.0252
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0282 0.015 0.0842
Onchocerca volvulus 0.0079 0.0031 0.1026
Echinococcus multilocularis survival motor neuron protein 1 0.0376 0.0205 0.1149
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0827 0.047 0.2631
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0012 0.0067
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0079 0.0031 0.0173
Echinococcus granulosus neuropeptide receptor A26 0.0819 0.0465 0.2602
Brugia malayi hypothetical protein 0.0341 0.0185 0.1034
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0165 0.0082 0.0164
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0031 0.0003 0.0018
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0053 0.0016 0.0089
Brugia malayi 6-phosphofructokinase 0.0072 0.0027 0.0153
Onchocerca volvulus 0.0341 0.0185 0.6066
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0069 0.0025 0.014
Schistosoma mansoni glutaminase 0.0284 0.0151 0.0847
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0084 0.0034 0.019
Loa Loa (eye worm) TYRA-2 protein 0.0341 0.0185 0.1035
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0079 0.0031 0.0016
Loa Loa (eye worm) hypothetical protein 0.0058 0.0019 0.0105
Treponema pallidum hypothetical protein 0.0103 0.0045 0.0044
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0246 0.0129 0.0716
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0792 0.0449 0.2516
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.0042
Echinococcus multilocularis receptor type guanylyl cyclase 0.0134 0.0063 0.0353
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0031 0.0031
Echinococcus granulosus aminopeptidase N 0.0302 0.0162 0.0907
Echinococcus granulosus neuropeptides capa receptor 0.0341 0.0185 0.1034
Treponema pallidum polypeptide deformylase (def) 0.0111 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0091 0.0038 0.0215
Loa Loa (eye worm) hypothetical protein 0.0026 0 0.0001
Trypanosoma brucei farnesyl pyrophosphate synthase 0.3072 0.1785 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.001 0.0054
Brugia malayi phosphofructokinase 0.0072 0.0027 0.0153
Plasmodium falciparum peptide deformylase 0.0111 0.005 0.005
Loa Loa (eye worm) peptidase family M13 containing protein 0.0087 0.0036 0.02
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0053 0.0016 0.0032
Leishmania major DNA polymerase kappa, putative 0.0028 0.0001 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.016 0.0079 0.0442
Echinococcus granulosus lamin dm0 0.0055 0.0017 0.0097
Toxoplasma gondii aminopeptidase N, putative 0.0031 0.0003 0.0003
Plasmodium vivax aspartyl protease, putative 0.0038 0.0007 0.0007
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0068 0.0025 0.0139
Mycobacterium ulcerans hypothetical protein 0.0032 0.0004 0.0004
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0053 0.0016 0.0089
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0341 0.0185 0.1034
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0115 0.0052 0.0293
Schistosoma mansoni jumonji domain containing protein 0.0055 0.0017 0.0094
Echinococcus multilocularis jumonji domain containing protein 0.0029 0.0002 0.0011
Echinococcus granulosus histone lysine methyltransferase setb 0.0069 0.0025 0.0141
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0053 0.0016 0.0089
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Schistosoma mansoni opsin-like receptor 0.0341 0.0185 0.1034
Schistosoma mansoni glutamate receptor AMPA 0.0149 0.0072 0.0404
Brugia malayi G protein-coupled receptor F59B2.13 0.0341 0.0185 0.1034
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0134 0.0063 0.0353
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0089 0.0037 0.0207
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0088 0.0037 0.0204
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0089 0.0037 0.0207
Loa Loa (eye worm) adenine phosphoribosyltransferase 0.0103 0.0045 0.0253
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0439 0.0242 0.1355
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Plasmodium vivax aspartyl protease, putative 0.0038 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0 0.0001
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0792 0.0449 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0007 0.004
Loa Loa (eye worm) hypothetical protein 0.0033 0.0004 0.0024
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Schistosoma mansoni peptidase Clp (S14 family) 0.0079 0.0031 0.0173
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.3072 0.1785 0.1785
Brugia malayi Melatonin receptor type 1A 0.0341 0.0185 0.1034
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.0792 0.0449 0.0449
Brugia malayi G-protein coupled receptor 0.0341 0.0185 0.1034
Mycobacterium ulcerans aminopeptidase N PepN 0.0031 0.0003 0.0003
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0036 0.0006 0.0033
Onchocerca volvulus 0.0038 0.0007 0.0232
Onchocerca volvulus 0.0089 0.0037 0.1213
Loa Loa (eye worm) G-protein coupled receptor 0.0341 0.0185 0.1035
Echinococcus multilocularis hypoxanthine guanine phosphoribosyltransferase 0.0439 0.0242 0.1355
Mycobacterium leprae PROBABLE HYDROLASE 0.0091 0.0038 0.0038
Trypanosoma brucei Polypeptide deformylase 1 0.0042 0.001 0.0054
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0792 0.0449 1
Schistosoma mansoni metabotropic glutamate receptor 0.0892 0.0508 0.2844
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0061 0.002 0.0114
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0001 0.0007
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0053 0.0016 0.0089
Trypanosoma brucei DNA polymerase eta, putative 0.004 0.0009 0.0048
Schistosoma mansoni glutamate receptor NMDA 0.0335 0.0181 0.1014
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.016 0.0079 0.0442
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0341 0.0185 0.1034
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0246 0.0129 0.0129
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0176 0.0088 0.1583
Brugia malayi putative neuropeptide receptor NPR1 0.0341 0.0185 0.1034
Schistosoma mansoni cathepsin D (A01 family) 0.0473 0.0262 0.1468
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0088 0.0037 0.0204
Onchocerca volvulus 0.0341 0.0185 0.6066
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0176 0.0088 0.0494
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0082 0.0033 0.0186
Echinococcus granulosus glutamate receptor 2 0.0206 0.0106 0.0591
Trypanosoma brucei Adenine phosphoribosyltransferase, putative 0.0103 0.0045 0.0252
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Trypanosoma brucei trypanothione reductase 0.0032 0.0004 0.0019
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0061 0.0021 0.0021
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0053 0.0016 0.0089
Echinococcus granulosus sex peptide receptor 0.0341 0.0185 0.1034
Mycobacterium tuberculosis Probable dehydrogenase 0.0073 0.0027 0.0055
Echinococcus multilocularis thyroid hormone receptor alpha 0.0182 0.0092 0.0513
Echinococcus granulosus dna polymerase kappa 0.0042 0.001 0.0054
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0089 0.0037 0.0207
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0122 0.0056 0.0056
Trichomonas vaginalis dihydrofolate synthase/folylpolyglutamate synthase, putative 0.0173 0.0087 0.0484
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0026 0 0.0001
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0073 0.0027 0.0055
Brugia malayi hypothetical protein 0.0341 0.0185 0.1034
Onchocerca volvulus 0.0545 0.0305 1
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.009 0.0038 0.021
Echinococcus granulosus tachykinin peptides receptor 99D 0.0341 0.0185 0.1034
Echinococcus granulosus 7TM GPCR rhodopsin 0.0341 0.0185 0.1034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0341 0.0185 0.1034
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0341 0.0185 0.1034
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0031 0.0003 0.0018
Trypanosoma cruzi endonuclease G, putative 0.0053 0.0016 0.0089
Brugia malayi dihydrofolate reductase family protein 0.0178 0.009 0.0501
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0053 0.0016 0.0089
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0084 0.0034 0.019
Brugia malayi G protein-coupled receptor 0.0341 0.0185 0.1034
Echinococcus multilocularis rhodopsin orphan GPCR 0.0341 0.0185 0.1034
Brugia malayi Matrixin family protein 0.0181 0.0091 0.0508
Echinococcus granulosus survival motor neuron protein 1 0.0376 0.0205 0.1149
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0792 0.0449 0.2516
Schistosoma mansoni lipoxygenase 0.0037 0.0006 0.0036
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0115 0.0052 0.0741
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0053 0.0016 0.0089
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0439 0.0242 0.1355
Echinococcus granulosus GPCR family 3 C terminal 0.0177 0.0089 0.0497
Trichomonas vaginalis phosphofructokinase, putative 0.0072 0.0027 0.0153
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0404 0.0221 0.124
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0031 0.0003 0.0018
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0056 0.0018 0.0098
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0176 0.0088 0.0494
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0341 0.0185 0.1034
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0792 0.0449 0.2516
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0936 0.0533 0.2987
Loa Loa (eye worm) hypothetical protein 0.0093 0.0039 0.0221
Trypanosoma brucei Adenine phosphoribosyltransferase, putative 0.0103 0.0045 0.0252
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0031 0.0031
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0042 0.001 0.0054
Onchocerca volvulus 0.0246 0.0129 0.4235
Leishmania major squalene synthase, putative 0.0298 0.016 0.0895
Trypanosoma cruzi DNA polymerase eta, putative 0.004 0.0009 0.0048
Schistosoma mansoni NAALADASE L peptidase (M28 family) 0.0092 0.0039 0.0216
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0032 0.0004 0.002
Schistosoma mansoni opsin-like receptor 0.0341 0.0185 0.1034
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0341 0.0185 0.1034
Echinococcus multilocularis tyrosine kinase 0.0134 0.0063 0.0353
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0828 0.047 0.0942
Trypanosoma cruzi trypanothione reductase, putative 0.0032 0.0004 0.0019
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0432 0.0238 0.1334
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0073 0.0027 0.0055
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0001 0.0001
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0404 0.0221 0.124
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0176 0.0088 0.0494
Echinococcus granulosus dro:myosuppressin receptor 0.0341 0.0185 0.1034
Echinococcus granulosus neuropeptide receptor 0.0341 0.0185 0.1034
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0089 0.0037 0.0207
Echinococcus granulosus neuropeptide FF receptor 2 0.0341 0.0185 0.1034
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0404 0.0221 0.124
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0272 0.0144 0.0807
Loa Loa (eye worm) glutathione reductase 0.0032 0.0004 0.002
Mycobacterium leprae Probable imidazole glycerol-phosphate dehydratase HisB 0.4215 0.2455 0.2455
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0792 0.0449 0.0449
Mycobacterium ulcerans epimerase 0.0032 0.0004 0.0004
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0117 0.0054 0.0299
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0091 0.0038 0.0076
Echinococcus granulosus nmda type glutamate receptor 0.0186 0.0094 0.0526
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0289 0.0154 0.0863
Echinococcus multilocularis nmda type glutamate receptor 0.0186 0.0094 0.0526
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0088 0.0037 0.0204
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0015 0.003
Echinococcus multilocularis dna polymerase kappa 0.0042 0.001 0.0054
Leishmania major DNA/RNA non-specific endonuclease-like protein 0.0053 0.0016 0.0089
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0013 0.0074
Onchocerca volvulus 0.0341 0.0185 0.6066
Schistosoma mansoni thyroid hormone receptor 0.0182 0.0092 0.0513
Toxoplasma gondii hypothetical protein 0.0289 0.0154 0.0154
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0117 0.0054 0.0299
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0088 0.0037 0.0204
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0341 0.0185 0.1034
Schistosoma mansoni amine GPCR 0.0341 0.0185 0.1034
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.004
Schistosoma mansoni neprilysin 0.0031 0.0003 0.0015
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0084 0.0034 0.0034
Schistosoma mansoni thyroid hormone receptor 0.0182 0.0092 0.0513
Plasmodium falciparum plasmepsin II 0.016 0.0079 0.0079
Echinococcus multilocularis purine nucleoside phosphorylase 0.0063 0.0022 0.0123
Schistosoma mansoni glutamate receptor NMDA 0.0259 0.0137 0.0766
Mycobacterium tuberculosis Probable oxidoreductase 0.0081 0.0032 0.0064
Loa Loa (eye worm) hypothetical protein 0.0055 0.0017 0.0097
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0827 0.047 0.2631
Echinococcus granulosus metabotropic glutamate receptor 5 0.1305 0.075 0.4199
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0341 0.0185 0.1034
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS 1.7089 1 1
Brugia malayi endonuclease G, mitochondrial precursor 0.0053 0.0016 0.0089
Schistosoma mansoni DNA polymerase eta 0.004 0.0009 0.0048
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Schistosoma mansoni amine GPCR 0.0341 0.0185 0.1034
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0828 0.047 0.0456
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase, putative 0.0439 0.0242 0.1355
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0176 0.0088 0.0494
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0086 0.0035 0.0344
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0341 0.0185 0.1034
Trypanosoma cruzi polyprenyl synthase, putative 0.0827 0.047 0.2631
Loa Loa (eye worm) hypothetical protein 0.0089 0.0037 0.0206
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.001 0.0054
Echinococcus multilocularis neuropeptide Y receptor 0.0341 0.0185 0.1034
Loa Loa (eye worm) 6-phosphofructokinase 0.0072 0.0027 0.0153
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0103 0.0046 0.0015
Echinococcus multilocularis endothelin converting enzyme 1 0.0117 0.0054 0.0299
Echinococcus granulosus lamin 0.0055 0.0017 0.0097
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0176 0.0088 0.0494
Entamoeba histolytica hypothetical protein 0.0134 0.0063 0.0997
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0082 0.0033 0.0186
Echinococcus granulosus neuropeptide s receptor 0.0819 0.0465 0.2602
Brugia malayi neuropeptide F receptor 0.0341 0.0185 0.1034
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0103 0.0046 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0012 0.0067
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0061 0.002 0.0114
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0058 0.0019 0.0104
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0176 0.0088 0.0494
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Loa Loa (eye worm) hypothetical protein 0.0036 0.0006 0.0034
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0084 0.0034 0.0315
Loa Loa (eye worm) TATA binding protein associated factor 0.0031 0.0003 0.0018
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.001 0.0054
Trichomonas vaginalis Ribose-phosphate pyrophosphokinase, putative 0.0103 0.0045 0.0252
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0117 0.0054 0.0107
Trypanosoma brucei endonuclease G, putative 0.0053 0.0016 0.0089
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0089 0.0037 0.0207
Echinococcus multilocularis NMDA receptor 0.0077 0.003 0.0166
Plasmodium vivax plasmepsin IV, putative 0.016 0.0079 0.0079
Schistosoma mansoni hypothetical protein 0.0341 0.0185 0.1034
Brugia malayi Glutamate receptor 2 precursor 0.0149 0.0072 0.0404
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.016 0.0079 0.0442
Loa Loa (eye worm) thioredoxin reductase 0.0032 0.0004 0.002
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0056 0.0018 0.0035
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.7089 1 1
Brugia malayi Peptidase family M1 containing protein 0.0302 0.0162 0.0907
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0061 0.002 0.0114
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0002 0.0012
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0108 0.0048 0.0268
Loa Loa (eye worm) hypothetical protein 0.0213 0.011 0.0615
Loa Loa (eye worm) hypothetical protein 0.0069 0.0025 0.0141
Plasmodium falciparum plasmepsin IV 0.016 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0376 0.0205 0.115
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0827 0.047 0.2631
Echinococcus granulosus hypothetical protein 0.0341 0.0185 0.1034
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0088 0.0037 0.0204
Leishmania major trypanothione reductase 0.0032 0.0004 0.0019
Brugia malayi ORL1-like opioid receptor 0.0341 0.0185 0.1034
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0246 0.0129 0.0722
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0084 0.0034 0.019
Toxoplasma gondii hypothetical protein 0.0027 0.0001 0.0001
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0115 0.0052 0.0292
Echinococcus multilocularis 6 phosphofructokinase 0.0072 0.0027 0.0153
Trichomonas vaginalis phosphofructokinase, putative 0.0072 0.0027 0.0153
Leishmania major solanesyl-diphosphate synthase, putative 0.0792 0.0449 0.2516
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0341 0.0185 0.1034
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0059 0.002 0.0109
Echinococcus granulosus tm gpcr rhodopsin 0.0341 0.0185 0.1034
Mycobacterium ulcerans aminopeptidase N PepN 0.0089 0.0037 0.0037
Brugia malayi RE15519p 0.0341 0.0185 0.1034
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0176 0.0088 0.0088
Mycobacterium ulcerans amidophosphoribosyltransferase 0.0103 0.0045 0.0045
Echinococcus granulosus purine nucleoside phosphorylase 0.0063 0.0022 0.0123
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0053 0.0016 0.0089
Schistosoma mansoni 6-phosphofructokinase 0.0072 0.0027 0.0153
Echinococcus granulosus geminin 0.0243 0.0127 0.0712
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0792 0.0449 0.0899
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0246 0.0129 0.0258
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0134 0.0063 0.0353
Brugia malayi sulfakinin receptor protein 0.0396 0.0217 0.1214
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0053 0.0016 0.0089
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0341 0.0185 0.1034
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0081 0.0032 0.0064
Brugia malayi hypothetical protein 0.0031 0.0003 0.0018
Mycobacterium ulcerans orotate phosphoribosyltransferase 0.0103 0.0045 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.001 0.0054
Loa Loa (eye worm) aminopeptidase N 0.0089 0.0037 0.0208
Loa Loa (eye worm) polyprenyl synthetase 0.3072 0.1785 1
Treponema pallidum folylpolyglutamate synthetase (folC) 0.0173 0.0087 0.0086
Echinococcus granulosus atrial natriuretic peptide receptor 0.0134 0.0063 0.0353
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0079 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0396 0.0217 0.1215
Brugia malayi Thrombospondin type 1 domain containing protein 0.019 0.0096 0.0539
Leishmania major orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative,OMPDCase-OPRTase, putative 0.0103 0.0045 0.0252
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0037 0.0006 0.0036
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0058 0.0019 0.0104
Mycobacterium leprae conserved hypothetical protein 0.0032 0.0004 0.0004
Plasmodium falciparum thioredoxin reductase 0.0032 0.0004 0.0003
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0341 0.0185 0.1034
Trypanosoma brucei Aminopeptidase M1, putative 0.0089 0.0037 0.0207
Brugia malayi putative neuropeptide receptor 0.0341 0.0185 0.1034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0341 0.0185 0.1034
Onchocerca volvulus 0.0341 0.0185 0.6066
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0031 0.0003 0.0003
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0115 0.0052 0.0052
Onchocerca volvulus 0.0341 0.0185 0.6066
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0341 0.0185 0.1034
Echinococcus multilocularis rhodopsin orphan GPCR 0.0341 0.0185 0.1034
Schistosoma mansoni hypothetical protein 0.0031 0.0003 0.0015
Echinococcus granulosus purine nucleoside phosphorylase 0.0063 0.0022 0.0123
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0134 0.0063 0.0354
Loa Loa (eye worm) zinc metallopeptidase 4 0.0029 0.0002 0.0009
Plasmodium vivax aspartyl proteinase, putative 0.016 0.0079 0.0079
Onchocerca volvulus 0.0077 0.003 0.0978
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0028 0.0001 0.0003
Chlamydia trachomatis endonuclease IV 0.0122 0.0056 0.0025
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras 0.6557 0.3828 0.7665
Echinococcus multilocularis rhodopsin orphan GPCR 0.0341 0.0185 0.1034
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0084 0.0034 0.019
Toxoplasma gondii hypothetical protein 0.0046 0.0012 0.0012
Plasmodium vivax aspartyl proteinase, putative 0.0038 0.0007 0.0007
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0115 0.0052 0.0292
Brugia malayi hypothetical protein 0.0341 0.0185 0.1034
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.0063 0.0022 0.0044
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0138 0.0066 0.0368
Plasmodium falciparum plasmepsin III 0.0038 0.0007 0.0007
Echinococcus granulosus purine nucleoside phosphorylase 0.0063 0.0022 0.0123
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0282 0.015 0.0842
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0115 0.0052 0.0292
Onchocerca volvulus Matrilysin homolog 0.0075 0.0029 0.0941
Echinococcus granulosus hypothetical protein 0.0037 0.0007 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0012 0.0067
Trypanosoma cruzi Peptide deformylase 2, putative 0.0042 0.001 0.0054
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0088 0.0037 0.0204
Giardia lamblia Prenyltransferase 0.0084 0.0034 0.0183
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0103 0.0045 0.0252
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0115 0.0052 0.0292
Onchocerca volvulus 0.0093 0.0039 0.129
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Schistosoma mansoni ATP-binding cassette transporter 0.0149 0.0072 0.0404
Brugia malayi Tachykinin-like peptides receptor 99D 0.0341 0.0185 0.1034
Loa Loa (eye worm) hypothetical protein 0.013 0.0061 0.0344
Onchocerca volvulus 0.0055 0.0017 0.0568
Toxoplasma gondii aminopeptidase n, putative 0.0031 0.0003 0.0003
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.3072 0.1785 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0007 0.004
Toxoplasma gondii aspartyl protease 0.0038 0.0007 0.0007
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0084 0.0034 0.019
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0479 0.0266 0.1489
Schistosoma mansoni myosin xvIII 0.0341 0.0185 0.1034
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0272 0.0144 0.0807
Trypanosoma cruzi protein farnesyltransferase, putative 0.0084 0.0034 0.019
Onchocerca volvulus 0.0106 0.0047 0.1542
Schistosoma mansoni orotidine 5'-phosphate decarboxylase 0.0103 0.0045 0.0252
Mycobacterium ulcerans aldehyde dehydrogenase 0.0056 0.0018 0.0017
Loa Loa (eye worm) glutaminase 2 0.0284 0.0151 0.0847
Echinococcus granulosus g protein coupled receptor 0.0341 0.0185 0.1034
Brugia malayi Receptor family ligand binding region containing protein 0.0134 0.0063 0.0353
Echinococcus multilocularis somatostatin receptor 0.0341 0.0185 0.1034
Brugia malayi Serotonin receptor 0.0341 0.0185 0.1034
Leishmania major endonuclease G, putative 0.0053 0.0016 0.0089
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0282 0.015 0.0842
Chlamydia trachomatis glutamine binding protein 0.0103 0.0046 0.0015
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0134 0.0063 0.0354
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Trypanosoma brucei Peptide deformylase 2 0.0042 0.001 0.0054
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0115 0.0052 0.0292
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0282 0.015 0.0842
Loa Loa (eye worm) neuropeptide F receptor 0.0341 0.0185 0.1035
Echinococcus multilocularis purine nucleoside phosphorylase 0.0063 0.0022 0.0123
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0079 0.0031 0.0031
Toxoplasma gondii orotate phosphoribosyltransferase 0.0103 0.0045 0.0045
Echinococcus multilocularis orexin receptor type 2 0.0341 0.0185 0.1034
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0063 0.0022 0.0022
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0063 0.0022 0.0123
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0029 0.0002 0.0009
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0079 0.0031 0.0173
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0084 0.0034 0.019
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0089 0.0037 0.0207
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0259 0.0137 0.0766
Echinococcus granulosus g protein coupled receptor 0.0341 0.0185 0.1034
Schistosoma mansoni biogenic amine receptor 0.0341 0.0185 0.1034
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0341 0.0185 0.1035
Brugia malayi Dihydrofolate reductase 0.0178 0.009 0.0501
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0134 0.0063 0.2072
Echinococcus granulosus glutamate NMDA receptor subunit 0.0259 0.0137 0.0766
Plasmodium falciparum plasmepsin VIII, putative 0.0038 0.0007 0.0007
Echinococcus granulosus neuropeptide receptor 0.0341 0.0185 0.1034
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0031 0.0003 0.0018
Mycobacterium tuberculosis Conserved hypothetical protein 0.0032 0.0004 0.0007
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0088 0.0037 0.0204
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.0042 0.001 0.0054
Schistosoma mansoni opsin-like receptor 0.0341 0.0185 0.1034
Giardia lamblia Guanine phosphoribosyltransferase 0.0439 0.0242 0.1348
Mycobacterium ulcerans aldehyde dehydrogenase 0.0056 0.0018 0.0017
Echinococcus granulosus tyrosine kinase 0.0134 0.0063 0.0353
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase 0.0439 0.0242 0.1355
Plasmodium vivax thioredoxin reductase, putative 0.0032 0.0004 0.0003
Schistosoma mansoni glutathione synthetase 0.0792 0.0449 0.2516
Echinococcus multilocularis metabotropic glutamate receptor 5 0.1305 0.075 0.4199
Loa Loa (eye worm) glutamate receptor 0.0413 0.0227 0.1271
Leishmania major polypeptide deformylase-like protein, putative 0.0042 0.001 0.0054
Loa Loa (eye worm) hypothetical protein 0.0089 0.0037 0.0206
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0178 0.009 0.0089
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0056 0.0018 0.0098
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0032 0.0004 0.0007
Echinococcus granulosus serotonin receptor 0.0341 0.0185 0.1034
Loa Loa (eye worm) thrombospondin type 1 domain-containing protein 0.019 0.0096 0.0539
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Onchocerca volvulus 0.0341 0.0185 0.6066
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Loa Loa (eye worm) polyprenyl synthetase 0.0792 0.0449 0.2516
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0061 0.002 0.0114
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0077 0.003 0.0166
Loa Loa (eye worm) RGC/RGC protein kinase 0.0134 0.0063 0.0354
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0015 0.003
Echinococcus multilocularis nmda type glutamate receptor 0.0232 0.0121 0.0678
Mycobacterium ulcerans imidazoleglycerol-phosphate dehydratase 0.8547 0.4994 0.4994
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.001 0.0054
Schistosoma mansoni survival motor neuron protein 0.0077 0.003 0.0167
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0053 0.0016 0.0089
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0792 0.0449 0.2516
Trichomonas vaginalis set domain proteins, putative 0.0545 0.0305 0.1705
Loa Loa (eye worm) hypothetical protein 0.0032 0.0004 0.0021
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0341 0.0185 0.6066
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0439 0.0242 0.1355
Loa Loa (eye worm) glutamate receptor 0.1069 0.0612 0.3426
Plasmodium vivax orotate phosphoribosyltransferase, putative 0.0103 0.0045 0.0045
Brugia malayi hypothetical protein 0.0134 0.0063 0.0353
Onchocerca volvulus 0.0439 0.0242 0.7943
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Loa Loa (eye worm) hypothetical protein 0.0088 0.0037 0.0205
Mycobacterium ulcerans phosphoribosylamine--glycine ligase 0.0052 0.0015 0.0015
Echinococcus granulosus g protein coupled receptor 0.0341 0.0185 0.1034
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Onchocerca volvulus Putative folylpolyglutamate synthase 0.0173 0.0087 0.2838
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0031 0.0003 0.0003
Brugia malayi Serotonin receptor 0.0341 0.0185 0.1034
Brugia malayi hypothetical protein 0.0038 0.0007 0.004
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0031 0.0003 0.0018
Loa Loa (eye worm) beta-lactamase 0.0026 0 0.0001
Brugia malayi Dopamine receptor protein 2 0.0341 0.0185 0.1034
Onchocerca volvulus 0.019 0.0096 0.316
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Brugia malayi hypothetical protein 0.0341 0.0185 0.1034
Schistosoma mansoni Adenine phosphoribosyltransferase 0.0103 0.0045 0.0252
Schistosoma mansoni aldehyde dehydrogenase 0.0056 0.0018 0.0098
Toxoplasma gondii aminopeptidase N protein 0.0031 0.0003 0.0003
Schistosoma mansoni neutral sphingomyelinase 0.0038 0.0007 0.0041
Loa Loa (eye worm) hypothetical protein 0.0087 0.0036 0.02
Echinococcus granulosus purine nucleoside phosphorylase 0.0063 0.0022 0.0123
Schistosoma mansoni aminopeptidase A (M01 family) 0.0031 0.0003 0.0018
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0053 0.0016 0.0089
Schistosoma mansoni hypothetical protein 0.0093 0.0039 0.022
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0068 0.0025 0.0139
Loa Loa (eye worm) hypothetical protein 0.0075 0.0029 0.0161
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0084 0.0034 0.019
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0029 0.0002 0.0009
Schistosoma mansoni hypothetical protein 0.0341 0.0185 0.1034
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0115 0.0052 0.0052
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0087 0.0036 0.02
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0341 0.0185 0.1034
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0053 0.0016 0.0089
Mycobacterium tuberculosis Probable imidazole glycerol-phosphate dehydratase HisB 0.8547 0.4994 1
Onchocerca volvulus Adenine phosphoribosyltransferase homolog 0.0103 0.0045 0.1478
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0031 0.0031
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0828 0.047 0.0942
Loa Loa (eye worm) phosphofructokinase 0.0072 0.0027 0.0153
Schistosoma mansoni glutamate receptor kainate 0.0149 0.0072 0.0404
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0029 0.0002 0.0009
Leishmania major extracellular receptor, putative 0.0134 0.0063 0.0353
Schistosoma mansoni lamin 0.0055 0.0017 0.0097
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0341 0.0185 0.1034
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0031 0.0003 0.0018
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0792 0.0449 0.0449
Onchocerca volvulus 0.0341 0.0185 0.6066
Onchocerca volvulus 0.0093 0.0039 0.129
Onchocerca volvulus 0.0341 0.0185 0.6066
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0341 0.0185 0.1034
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0017 0.0097
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0088 0.0037 0.0204
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0073 0.0027 0.0055
Onchocerca volvulus 0.0088 0.0037 0.1196
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0007 0.004
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0059 0.002 0.0109
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0341 0.0185 0.1035
Echinococcus granulosus leukotriene A 4 hydrolase 0.0031 0.0003 0.0018
Echinococcus granulosus orexin receptor type 2 0.0341 0.0185 0.1034
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.3072 0.1785 1
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Echinococcus granulosus metabotropic glutamate receptor 2 0.0892 0.0508 0.2844
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1341 0.0771 0.4317
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0177 0.0089 0.2914
Schistosoma mansoni neuropeptide receptor 0.0341 0.0185 0.1034
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0176 0.0088 0.0088
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0053 0.0016 0.0089
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0404 0.0221 0.0221
Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyl transferase HXGPRT 0.0439 0.0242 0.0242
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0088 0.0037 0.0204
Brugia malayi jmjC domain containing protein 0.0069 0.0025 0.014
Loa Loa (eye worm) FolC protein 0.0173 0.0087 0.0485
Leishmania major farnesyltransferase beta subunit 0.0084 0.0034 0.019
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0088 0.0037 0.0204
Brugia malayi Peptidase family M1 containing protein 0.0031 0.0003 0.0018
Treponema pallidum adenine phosphoribosyltransferase 0.0103 0.0045 0.0044
Echinococcus multilocularis neuropeptide receptor 0.0341 0.0185 0.1034
Schistosoma mansoni hypothetical protein 0.0033 0.0004 0.0024
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0061 0.002 0.0114
Onchocerca volvulus 0.0341 0.0185 0.6066
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0084 0.0034 0.019
Schistosoma mansoni biogenic amine (5HT) receptor 0.0341 0.0185 0.1034
Schistosoma mansoni hypothetical protein 0.0341 0.0185 0.1034
Loa Loa (eye worm) hypothetical protein 0.0134 0.0063 0.0354
Echinococcus granulosus purine nucleoside phosphorylase 0.0063 0.0022 0.0123
Schistosoma mansoni glutamate receptor kainate 0.0149 0.0072 0.0404
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0074 0.0028 0.0159
Mycobacterium tuberculosis Conserved hypothetical protein 0.0103 0.0045 0.009
Echinococcus granulosus folylpolyglutamate synthase, mitochondrial 0.0173 0.0087 0.0484
Mycobacterium tuberculosis Probable orotate phosphoribosyltransferase PyrE (OPRT) (oprtase) 0.0103 0.0045 0.009
Plasmodium vivax aspartyl protease, putative 0.0038 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Echinococcus multilocularis neuropeptide Y receptor 0.0341 0.0185 0.1034
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0341 0.0185 0.1034
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0013 0.0074
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0084 0.0034 0.0034
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0072 0.0027 0.0153
Loa Loa (eye worm) hypothetical protein 0.0134 0.0063 0.0354
Onchocerca volvulus 0.0341 0.0185 0.6066
Brugia malayi 6-phosphofructokinase 0.0072 0.0027 0.0153
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0842 0.0478 0.2678
Mycobacterium tuberculosis Probable phytoene synthase PhyA 0.0093 0.0039 0.0079
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.3072 0.1785 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0341 0.0185 0.1034
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0439 0.0242 0.1355
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.3072 0.1785 0.1785
Brugia malayi Pepsin A precursor 0.0038 0.0007 0.004
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0341 0.0185 0.1034
Echinococcus multilocularis dro:myosuppressin receptor 0.0341 0.0185 0.1034
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.001 0.0054
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase 0.0439 0.0242 0.1355
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.001 0.0054
Loa Loa (eye worm) glutamate receptor 2 0.0149 0.0072 0.0404
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0828 0.047 0.0441
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0341 0.0185 0.1034
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0282 0.015 0.0842
Brugia malayi Polyprenyl synthetase family protein 0.0792 0.0449 0.2516
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0031 0.0003 0.0018
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0031 0.0003 0.0018
Echinococcus multilocularis G-protein coupled receptor, putative 0.0341 0.0185 0.1034
Schistosoma mansoni amine GPCR 0.0341 0.0185 0.1034
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0341 0.0185 0.1034
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0103 0.0045 0.0252
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0282 0.015 0.0842
Brugia malayi Hemopexin family protein 0.0106 0.0047 0.0263
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0103 0.0046 0.0091
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0084 0.0034 0.019
Entamoeba histolytica aminopeptidase, putative 0.0089 0.0037 0.0388
Loa Loa (eye worm) hypothetical protein 0.0031 0.0003 0.0018
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0246 0.0129 0.2533
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.001 0.0058
Trichomonas vaginalis ribose-phosphate pyrophosphokinase, putative 0.0103 0.0045 0.0252
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.3072 0.1785 0.3575
Echinococcus granulosus somatostatin receptor 0.0341 0.0185 0.1034
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0053 0.0016 0.0089
Echinococcus multilocularis rhodopsin orphan GPCR 0.0341 0.0185 0.1034
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0089 0.0037 0.0207
Loa Loa (eye worm) hypothetical protein 0.0089 0.0037 0.0206
Echinococcus multilocularis neutral sphingomyelinase 0.0038 0.0007 0.0041
Schistosoma mansoni hypothetical protein 0.019 0.0096 0.0539
Schistosoma mansoni hypothetical protein 0.0031 0.0003 0.0015
Schistosoma mansoni biogenic amine (5HT) receptor 0.0341 0.0185 0.1034
Onchocerca volvulus 0.0341 0.0185 0.6066
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0341 0.0185 0.1034
Leishmania major DNA polymerase eta, putative 0.004 0.0009 0.0048
Onchocerca volvulus Poor gastrulation protein homolog 0.0177 0.0089 0.2914
Echinococcus multilocularis allatostatin A receptor 0.0341 0.0185 0.1034
Plasmodium vivax hypothetical protein, conserved 0.0026 0 0.0000019522
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0086 0.0035 0.0344
Brugia malayi Thioredoxin reductase 0.0032 0.0004 0.0019
Mycobacterium leprae probable zinc metalloprotease 0.0117 0.0054 0.0053
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0341 0.0185 0.1034
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0081 0.0032 0.0064
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.016 0.0079 0.0079
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0176 0.0088 0.0494
Mycobacterium leprae PROBABLE FOLYLPOLYGLUTAMATE SYNTHASE PROTEIN FOLC (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS) 0.0173 0.0087 0.0086
Echinococcus granulosus uridine 5' monophosphate synthase 0.0103 0.0045 0.0252
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0038 0.0007 0.004
Brugia malayi M-phase phosphoprotein, mpp8 0.0093 0.0039 0.022
Loa Loa (eye worm) hypothetical protein 0.0088 0.0037 0.0205
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0176 0.0088 0.0495
Trypanosoma brucei hypothetical protein, conserved 0.0115 0.0052 0.0292
Brugia malayi hypothetical protein 0.0341 0.0185 0.1034
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0115 0.0052 0.0052
Loa Loa (eye worm) matrixin family protein 0.0166 0.0082 0.046
Loa Loa (eye worm) 6-phosphofructokinase 0.0072 0.0027 0.0153
Schistosoma mansoni hypothetical protein 0.0031 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0115 0.0052 0.0292
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Brugia malayi Phosphoribosyl transferase domain containing protein 0.0439 0.0242 0.1355
Schistosoma mansoni hypothetical protein 0.0243 0.0127 0.0712
Brugia malayi AKH receptor 0.0341 0.0185 0.1034
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.3072 0.1785 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0341 0.0185 0.1034
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0176 0.0088 0.0494
Onchocerca volvulus 0.0341 0.0185 0.6066
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0053 0.0016 0.0089
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Mycobacterium leprae PROBABLE PHOSPHORIBOSYLAMINE--GLYCINE LIGASE PURD (GARS) (GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE) (PHOSPHORIBOSYLGLYCINAMIDE SYNT 0.0052 0.0015 0.0015
Brugia malayi glutathione reductase 0.0032 0.0004 0.0019
Echinococcus multilocularis conserved hypothetical protein 0.0037 0.0007 0.0037
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0088 0.0037 0.0204
Brugia malayi Matrixin family protein 0.0075 0.0029 0.016
Loa Loa (eye worm) RGC/RGC protein kinase 0.0134 0.0063 0.0354
Echinococcus granulosus endothelin converting enzyme 1 0.0117 0.0054 0.0299
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0053 0.0016 0.0089
Brugia malayi Pre-SET motif family protein 0.0069 0.0025 0.0141
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0178 0.009 0.0089
Schistosoma mansoni aldehyde dehydrogenase 0.0056 0.0018 0.0098
Schistosoma mansoni hypothetical protein 0.0077 0.003 0.0166
Trichomonas vaginalis DNA polymerase eta, putative 0.0042 0.001 0.0054
Schistosoma mansoni adenoreceptor 0.0341 0.0185 0.1034
Trypanosoma brucei endonuclease G, putative 0.0053 0.0016 0.0089
Echinococcus multilocularis transcription factor Dp 1 0.0035 0.0005 0.003
Schistosoma mansoni intermediate filament proteins 0.0055 0.0017 0.0097
Echinococcus multilocularis expressed conserved protein 0.0037 0.0007 0.0037
Onchocerca volvulus 0.0038 0.0007 0.0232
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0404 0.0221 0.124
Echinococcus multilocularis fmrfamide receptor 0.0341 0.0185 0.1034
Loa Loa (eye worm) hypothetical protein 0.0271 0.0144 0.0805
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0122 0.0056 0.0113
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0089 0.0037 0.0207
Schistosoma mansoni hypothetical protein 0.0106 0.0047 0.0263
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0246 0.0129 0.0722
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0072 0.0027 0.0055
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0053 0.0016 0.0089
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0053 0.0016 0.0089
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0053 0.0016 0.0089
Schistosoma mansoni tyrosine kinase 0.0134 0.0063 0.0353
Schistosoma mansoni hypothetical protein 0.0243 0.0127 0.0712
Plasmodium vivax dihydrofolate synthase/folylpolyglutamate synthase, putative 0.0173 0.0087 0.0086
Brugia malayi Dopamine receptor 0.0341 0.0185 0.1034
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0169 0.0084 0.0468
Leishmania major adenine phosphoribosyltransferase 0.0103 0.0045 0.0252
Echinococcus multilocularis rhodopsin orphan GPCR 0.0341 0.0185 0.1034
Toxoplasma gondii bifunctional protein FolC subfamily protein 0.0173 0.0087 0.0086
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0056 0.0018 0.0098
Brugia malayi hypothetical protein 0.0341 0.0185 0.1034
Loa Loa (eye worm) matrixin family protein 0.0181 0.0091 0.0509
Echinococcus granulosus folylpolyglutamate synthase mitochondrial 0.0173 0.0087 0.0484
Echinococcus granulosus rhodopsin orphan GPCR 0.0341 0.0185 0.1034
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0074 0.0028 0.0159
Brugia malayi Eukaryotic aspartyl protease family protein 0.0038 0.0007 0.004
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 1.7089 1 1
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0246 0.0129 0.0722
Onchocerca volvulus 0.0341 0.0185 0.6066
Brugia malayi hypothetical protein 0.0376 0.0205 0.1149
Mycobacterium tuberculosis Probable folylpolyglutamate synthase protein FolC (folylpoly-gamma-glutamate synthetase) (FPGS) 0.0173 0.0087 0.0173
Entamoeba histolytica phosphofructokinase, putative 0.0072 0.0027 0.0162
Loa Loa (eye worm) hypothetical protein 0.0026 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0093 0.0039 0.0221
Echinococcus granulosus glutamate receptor subunit protein glur 0.0077 0.003 0.0166
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0084 0.0034 0.019
Echinococcus multilocularis folylpolyglutamate synthase, mitochondrial 0.0173 0.0087 0.0484
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0103 0.0045 0.0252
Loa Loa (eye worm) cytochrome P450 family protein 0.0039 0.0008 0.0044
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0089 0.0037 0.0207
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0053 0.0016 0.0089
Echinococcus granulosus g-protein coupled receptor 0.0341 0.0185 0.1034
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0031 0.0003 0.0018
Echinococcus multilocularis musashi 0.0055 0.0017 0.0097
Echinococcus granulosus intermediate filament protein 0.0055 0.0017 0.0097
Schistosoma mansoni growth hormone secretagogue receptor 0.0341 0.0185 0.1034
Onchocerca volvulus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog 0.0093 0.0039 0.1292
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0053 0.0016 0.0089
Leishmania major xanthine phosphoribosyltransferase 0.0439 0.0242 0.1355
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0115 0.0052 0.0292
Echinococcus granulosus tm gpcr rhodopsin 0.0341 0.0185 0.1034
Leishmania major hypothetical protein, conserved 0.0093 0.0039 0.022
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0053 0.0016 0.0089
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0792 0.0449 1
Brugia malayi Dopamine receptor protein 1 0.0341 0.0185 0.1034
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0404 0.0221 0.124
Onchocerca volvulus 0.0058 0.0019 0.0618
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Toxoplasma gondii hypothetical protein 0.0115 0.0052 0.0052
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0017 0.0097
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0103 0.0046 0.0045
Plasmodium falciparum plasmepsin VI 0.016 0.0079 0.0079
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.3072 0.1785 1
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0082 0.0033 0.0186
Brugia malayi TATA binding protein associated factor 0.0031 0.0003 0.0018
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0073 0.0027 0.0055
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.0792 0.0449 0.0449
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0792 0.0449 0.0449
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0089 0.0037 0.0207
Echinococcus multilocularis G protein coupled receptor 139 0.0341 0.0185 0.1034
Echinococcus multilocularis neuropeptide receptor 0.0341 0.0185 0.1034
Echinococcus granulosus alpha 1A adrenergic receptor 0.0341 0.0185 0.1034
Trypanosoma cruzi aminopeptidase, putative 0.0031 0.0003 0.0018
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0246 0.0129 0.2533
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0103 0.0045 0.0252
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0069 0.0025 0.0025
Mycobacterium ulcerans hypoxanthine-guanine phosphoribosyltransferase Hpt 0.0439 0.0242 0.0242
Echinococcus granulosus biogenic amine 5HT receptor 0.0341 0.0185 0.1034
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0007 0.004
Schistosoma mansoni neuropeptide f receptor 76f 0.0341 0.0185 0.1034
Echinococcus multilocularis sex peptide receptor 0.0341 0.0185 0.1034
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0053 0.0016 0.0089
Mycobacterium ulcerans hydrolase 0.0091 0.0038 0.0038
Trypanosoma brucei unspecified product 0.0038 0.0007 0.0038
Onchocerca volvulus 0.0341 0.0185 0.6066
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0103 0.0045 0.0252
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0015 0.0084
Toxoplasma gondii hypothetical protein 0.0111 0.005 0.005
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0053 0.0016 0.0089
Chlamydia trachomatis peptide deformylase 0.0111 0.005 0.0019
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0089 0.0037 0.0207
Echinococcus multilocularis neuropeptide FF receptor 2 0.0341 0.0185 0.1034
Schistosoma mansoni farnesyl pyrophosphate synthase 0.3072 0.1785 1
Loa Loa (eye worm) glutaminase 0.0284 0.0151 0.0847
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0341 0.0185 0.1034
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0031 0.0003 0.0018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0341 0.0185 0.1034
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0077 0.003 0.0166
Onchocerca volvulus 0.0134 0.0063 0.2072
Schistosoma mansoni neprilysin-2 (M13 family) 0.0059 0.002 0.0109
Loa Loa (eye worm) hypothetical protein 0.0093 0.0039 0.0221
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0053 0.0016 0.0089
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0066 0.0024 0.0132
Echinococcus multilocularis GPCR, family 3, C terminal 0.0177 0.0089 0.0497
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0053 0.0016 0.0089
Echinococcus granulosus dihydrofolate reductase 0.0178 0.009 0.0501
Trichomonas vaginalis phosphofructokinase, putative 0.0072 0.0027 0.0153
Loa Loa (eye worm) hypothetical protein 0.0075 0.0029 0.0161
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0089 0.0037 0.0207
Brugia malayi glutaminase DH11.1 0.0284 0.0151 0.0847
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.016 0.0079 0.0442
Trypanosoma cruzi protein farnesyltransferase, putative 0.0084 0.0034 0.019
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.0042 0.001 0.0054
Wolbachia endosymbiont of Brugia malayi orotate phosphoribosyltransferase 0.0103 0.0045 0.003
Loa Loa (eye worm) hypothetical protein 0.0117 0.0054 0.03
Schistosoma mansoni neuropeptide receptor 0.0341 0.0185 0.1034
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0246 0.0129 0.0722
Echinococcus granulosus farnesyl pyrophosphate synthase 0.3072 0.1785 1
Echinococcus granulosus fmrfamide receptor 0.0341 0.0185 0.1034
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.001 0.0054
Schistosoma mansoni alpha-1 adrenergic receptor 0.0341 0.0185 0.1034
Giardia lamblia Rab geranylgeranyltransferase 0.0115 0.0052 0.0285
Loa Loa (eye worm) hypothetical protein 0.0074 0.0028 0.0159
Echinococcus granulosus ectonucleotide 0.0074 0.0028 0.0159
Loa Loa (eye worm) melatonin receptor type 1A 0.0341 0.0185 0.1035
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0031 0.0031
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0053 0.0016 0.0089
Loa Loa (eye worm) hypothetical protein 0.0088 0.0037 0.0205
Trypanosoma cruzi folylpolyglutamate synthase, putative 0.0173 0.0087 0.0484
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0007 0.004
Mycobacterium ulcerans endonuclease IV 0.0122 0.0056 0.0056
Onchocerca volvulus Putative neutral sphingomyelinase 0.0038 0.0007 0.0242
Echinococcus granulosus Endonuclease G 0.0053 0.0016 0.0089
Echinococcus multilocularis rhodopsin orphan GPCR 0.0341 0.0185 0.1034
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.001 0.0054
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Trypanosoma cruzi lanosterol synthase, putative 0.0053 0.0016 0.009
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.0063 0.0022 0.0116
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.016 0.0079 0.0442
Wolbachia endosymbiont of Brugia malayi peptide deformylase 0.0111 0.005 0.0034
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0084 0.0034 0.019
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0341 0.0185 0.1034
Echinococcus multilocularis ectonucleotide 0.0074 0.0028 0.0159
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0115 0.0052 0.0292
Echinococcus multilocularis glutamate receptor 2 0.0149 0.0072 0.0404
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0122 0.0056 0.0056
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0341 0.0185 0.1034
Schistosoma mansoni hypothetical protein 0.0031 0.0003 0.0015
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.001 0.001
Plasmodium vivax SET domain protein, putative 0.0069 0.0025 0.0025
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0341 0.0185 0.1034
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0311 0.0167 0.0936
Giardia lamblia Rab geranylgeranyltransferase 0.0404 0.0221 0.1233
Toxoplasma gondii aspartyl protease ASP1 0.016 0.0079 0.0079
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0068 0.0025 0.0025
Mycobacterium leprae PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) 0.0111 0.005 0.005
Mycobacterium tuberculosis Amidophosphoribosyltransferase PurF (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (gpatase) 0.0103 0.0045 0.009
Schistosoma mansoni biogenic amine receptor 0.0341 0.0185 0.1034
Loa Loa (eye worm) hypothetical protein 0.0122 0.0056 0.0316
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0053 0.0016 0.0089
Trypanosoma cruzi folylpolyglutamate synthetase 0.0173 0.0087 0.0484
Leishmania major hypoxanthine-guanine phosphoribosyltransferase 0.0439 0.0242 0.1355
Echinococcus multilocularis rhodopsin orphan GPCR 0.0341 0.0185 0.1034
Loa Loa (eye worm) peptidase family M13 containing protein 0.0087 0.0036 0.02
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0007 0.004
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0015 0.0084
Trypanosoma cruzi Aminopeptidase M1, putative 0.0089 0.0037 0.0207
Trypanosoma brucei folylpolyglutamate synthase, putative 0.0173 0.0087 0.0484
Echinococcus granulosus jumonji domain containing protein 0.0029 0.0002 0.0011
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0341 0.0185 0.1034
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0176 0.0088 0.0494
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0032 0.0004 0.0004
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0341 0.0185 0.1034
Echinococcus multilocularis glutamate receptor 2 0.0206 0.0106 0.0591
Echinococcus granulosus neutral sphingomyelinase 0.0038 0.0007 0.0041
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0002 0.0013
Giardia lamblia Adenine phosphoribosyltransferase 0.0103 0.0045 0.0245
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0038 0.0007 0.004
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0341 0.0185 0.1034
Brugia malayi Pre-SET motif family protein 0.0479 0.0266 0.1488
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0073 0.0027 0.0027
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0552 0.0308 0.1728
Brugia malayi Matrixin family protein 0.0075 0.0029 0.016
Loa Loa (eye worm) hypothetical protein 0.0143 0.0069 0.0386
Schistosoma mansoni lamin 0.0055 0.0017 0.0097
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0176 0.0088 0.0495
Schistosoma mansoni glutamate receptor AMPA 0.0149 0.0072 0.0404
Schistosoma mansoni dihydrofolate reductase 0.0178 0.009 0.0501
Loa Loa (eye worm) hypothetical protein 0.0504 0.0281 0.1572
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Trypanosoma brucei Aminopeptidase M1, putative 0.0089 0.0037 0.0207
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0115 0.0052 0.0292
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0013 0.0074
Schistosoma mansoni hypothetical protein 0.0031 0.0003 0.0015
Echinococcus multilocularis purine nucleoside phosphorylase 0.0063 0.0022 0.0123
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.1172 0.0672 0.3761
Echinococcus granulosus rhodopsin orphan GPCR 0.0341 0.0185 0.1034
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0029 0.0002 0.0009
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0053 0.0016 0.0089
Mycobacterium tuberculosis Probable pyrimidine operon regulatory protein PyrR 0.0103 0.0045 0.009
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0001 0.0003
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0115 0.0052 0.0292
Brugia malayi hypothetical protein 0.0396 0.0217 0.1214
Loa Loa (eye worm) hypothetical protein 0.0075 0.0029 0.0161
Leishmania major lanosterol synthase, putative 0.0031 0.0003 0.0015
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0827 0.047 0.2631
Mycobacterium leprae AMIDOPHOSPHORIBOSYLTRANSFERASE PURF (GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE) (GPATASE) 0.0103 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.005 0.0014 0.0081
Echinococcus granulosus hypoxanthine guanine phosphoribosyltransferase 0.0439 0.0242 0.1355
Brugia malayi orotate phosphoribosyltransferase family protein 0.0103 0.0045 0.0252
Mycobacterium leprae PROBABLE OROTATE PHOSPHORIBOSYLTRANSFERASE PYRE (OPRT) (OPRTASE) 0.0103 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.0169 0.0084 0.0468
Echinococcus multilocularis expressed protein 0.0249 0.0131 0.0731
Schistosoma mansoni hypothetical protein 0.0031 0.0003 0.0015
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0103 0.0046 0.0045
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0404 0.0221 0.124
Mycobacterium ulcerans aldehyde dehydrogenase 0.0056 0.0018 0.0017
Schistosoma mansoni uracil phosphoribosyltransferase 0.0103 0.0045 0.0252
Brugia malayi Matrixin family protein 0.0075 0.0029 0.016
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0053 0.0016 0.0089
Wolbachia endosymbiont of Brugia malayi amidophosphoribosyltransferase 0.0103 0.0045 0.003
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0115 0.0052 0.0105
Echinococcus multilocularis thioredoxin glutathione reductase 0.0032 0.0004 0.0019
Schistosoma mansoni neuropeptide F-like receptor 0.0341 0.0185 0.1034
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0031 0.0003 0.0018
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0341 0.0185 0.1034
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0792 0.0449 0.2516
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0053 0.0016 0.0089
Mycobacterium ulcerans zinc metalloprotease 0.0117 0.0054 0.0053
Brugia malayi hypothetical protein 0.0341 0.0185 0.1034
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Plasmodium falciparum plasmepsin I 0.016 0.0079 0.0079
Mycobacterium ulcerans glutaminase 0.0284 0.0151 0.0151
Schistosoma mansoni metabotropic glutamate receptor 0.0547 0.0305 0.1709
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0061 0.002 0.0114
Echinococcus multilocularis g protein coupled receptor 0.0341 0.0185 0.1034
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0103 0.0045 0.0252
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0077 0.003 0.0166
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0027 0.0001 0.0031
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0892 0.0508 0.2844
Brugia malayi Angiotensin-converting enzyme family protein 0.0228 0.0118 0.0662
Echinococcus multilocularis purine nucleoside phosphorylase 0.0063 0.0022 0.0123
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0341 0.0185 0.1034
Mycobacterium ulcerans purine nucleoside phosphorylase 0.0063 0.0022 0.0022
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0084 0.0034 0.0034
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0122 0.0056 0.0315
Echinococcus granulosus neuropeptide Y receptor 0.0341 0.0185 0.1034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0341 0.0185 0.1034
Plasmodium vivax peptide deformylase, putative 0.0111 0.005 0.005
Mycobacterium ulcerans bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 0.0103 0.0045 0.0045
Echinococcus granulosus purine nucleoside phosphorylase 0.0063 0.0022 0.0123
Echinococcus granulosus neuropeptides capa receptor 0.0341 0.0185 0.1034
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0038 0.0007 0.0041
Toxoplasma gondii DNA/RNA non-specific endonuclease 0.0053 0.0016 0.0016
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0115 0.0052 0.0292
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0792 0.0449 0.2516
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0077 0.003 0.0167
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0077 0.003 0.0166
Plasmodium falciparum plasmepsin V 0.0038 0.0007 0.0007
Trypanosoma brucei lanosterol synthase 0.0053 0.0016 0.009
Echinococcus granulosus G protein coupled receptor 139 0.0341 0.0185 0.1034
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0089 0.0037 0.0207
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0061 0.002 0.0114
Echinococcus multilocularis purine nucleoside phosphorylase 0.0063 0.0022 0.0123
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0439 0.0242 0.1355
Loa Loa (eye worm) hypothetical protein 0.0117 0.0054 0.03
Schistosoma mansoni neuropeptide receptor 0.0341 0.0185 0.1034
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.004
Brugia malayi Peptidase family M13 containing protein 0.0117 0.0054 0.0299
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0079 0.0031 0.0175
Schistosoma mansoni neuropeptide receptor 0.0341 0.0185 0.1034
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0029 0.0002 0.0009
Brugia malayi Cytochrome P450 family protein 0.0039 0.0008 0.0043
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0053 0.0016 0.0089
Echinococcus granulosus peptide allatostatin:somatostatin 0.0341 0.0185 0.1034
Echinococcus granulosus 6 phosphofructokinase 0.0072 0.0027 0.0153
Loa Loa (eye worm) hypothetical protein 0.004 0.0009 0.0048
Onchocerca volvulus 0.0134 0.0063 0.2072
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0059 0.002 0.0109
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.3072 0.1785 0.1785
Loa Loa (eye worm) hypothetical protein 0.0087 0.0036 0.02
Echinococcus multilocularis lamin dm0 0.0055 0.0017 0.0097
Schistosoma mansoni microtubule-associated protein tau 0.1052 0.0602 0.337
Loa Loa (eye worm) hypothetical protein 0.0087 0.0036 0.02
Toxoplasma gondii peptidase family M13 protein 0.0117 0.0054 0.0053
Loa Loa (eye worm) orotate phosphoribosyltransferase 0.0103 0.0045 0.0253
Loa Loa (eye worm) neuropeptide F receptor 0.0341 0.0185 0.1035
Schistosoma mansoni glutamate receptor kainate 0.0149 0.0072 0.0404
Echinococcus granulosus allatostatin A receptor 0.0341 0.0185 0.1034
Echinococcus multilocularis neuropeptides capa receptor 0.0341 0.0185 0.1034
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0053 0.0016 0.0089
Treponema pallidum phosphoribosylpyrophosphate synthetase 0.0103 0.0045 0.0044
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0341 0.0185 0.1035
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0088 0.0037 0.0204
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0053 0.0016 0.0089
Brugia malayi FolC bifunctional protein 0.0173 0.0087 0.0484
Echinococcus granulosus transcription factor Dp 1 0.0035 0.0005 0.003
Echinococcus granulosus expressed protein 0.0249 0.0131 0.0731
Trypanosoma cruzi squalene synthase, putative 0.0298 0.016 0.0895
Mycobacterium tuberculosis Conserved protein 0.0103 0.0045 0.009
Trypanosoma cruzi lanosterol synthase, putative 0.0053 0.0016 0.009
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0341 0.0185 0.1034
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0404 0.0221 0.124
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0246 0.0129 0.0722
Plasmodium vivax glutathione reductase, putative 0.0032 0.0004 0.0003
Onchocerca volvulus 0.0075 0.0029 0.0941
Echinococcus multilocularis geminin 0.0243 0.0127 0.0712
Echinococcus granulosus thioredoxin glutathione reductase 0.0032 0.0004 0.0019
Echinococcus granulosus Squalene phytoene synthase 0.0093 0.0039 0.022
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0088 0.0037 0.0204
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0069 0.0025 0.0141
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0004 0.0024
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0072 0.0027 0.0027
Echinococcus multilocularis adenine phosphoribosyltransferase 0.0103 0.0045 0.0252
Schistosoma mansoni cathepsin D (A01 family) 0.0473 0.0262 0.1468
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.001 0.0054
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0115 0.0052 0.0293
Mycobacterium leprae Probable hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (IMP pho 0.0336 0.0182 0.0182
Echinococcus multilocularis serotonin receptor 0.0341 0.0185 0.1034
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0036 0.0006 0.0033
Onchocerca volvulus 0.0341 0.0185 0.6066
Onchocerca volvulus Neuropeptide F receptor homolog 0.0341 0.0185 0.6066
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0246 0.0129 0.0722
Brugia malayi neuropeptide F receptor 0.0341 0.0185 0.1034
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0037 0.0006 0.0036
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0115 0.0052 0.0052
Echinococcus granulosus adenine phosphoribosyltransferase 0.0103 0.0045 0.0252
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0069 0.0025 0.014
Onchocerca volvulus 0.0088 0.0037 0.1196
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0031 0.003
Echinococcus multilocularis Endonuclease G 0.0053 0.0016 0.0089
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0072 0.0027 0.0153
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0091 0.0038 0.0214
Echinococcus multilocularis fmrfamide receptor 0.0341 0.0185 0.1034
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0404 0.0221 0.124
Loa Loa (eye worm) aspartyl protease 6 0.0038 0.0007 0.004
Schistosoma mansoni amine GPCR 0.0341 0.0185 0.1034
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0015 0.0015
Trypanosoma cruzi squalene synthase, putative 0.0298 0.016 0.0895
Trichomonas vaginalis hypoxanthine-guanine phosphoribosyltransferase, putative 0.0439 0.0242 0.1355
Loa Loa (eye worm) hypothetical protein 0.0134 0.0063 0.0354
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0341 0.0185 0.1034
Loa Loa (eye worm) hypothetical protein 0.0134 0.0063 0.0354
Echinococcus granulosus tm gpcr rhodopsin 0.1341 0.0771 0.4317
Trichomonas vaginalis phosphofructokinase, putative 0.0072 0.0027 0.0153
Loa Loa (eye worm) hypothetical protein 0.0095 0.0041 0.0227
Brugia malayi larval opioid receptor 0.0341 0.0185 0.1034
Brugia malayi hypothetical protein 0.0341 0.0185 0.1034
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0089 0.0037 0.0207
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0178 0.009 0.0179
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0028 0.0001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0048 0.0013 0.0074
Echinococcus granulosus purine nucleoside phosphorylase 0.0063 0.0022 0.0123
Schistosoma mansoni biogenic amine receptor 0.0341 0.0185 0.1034
Echinococcus granulosus purine nucleoside phosphorylase 0.0063 0.0022 0.0123
Schistosoma mansoni purine nucleoside phosphorylase 0.0063 0.0022 0.0123
Echinococcus granulosus rhodopsin orphan GPCR 0.0341 0.0185 0.1034
Loa Loa (eye worm) RGC/RGC protein kinase 0.0134 0.0063 0.0354
Echinococcus multilocularis glutamate receptor NMDA 0.0053 0.0016 0.0087
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.001 0.0054
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Brugia malayi Peptidase family M1 containing protein 0.0089 0.0037 0.0207
Plasmodium falciparum dihydrofolate synthase/folylpolyglutamate synthase 0.0173 0.0087 0.0086
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0341 0.0185 0.1034
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0069 0.0025 0.0141
Loa Loa (eye worm) hypothetical protein 0.0026 0 0.0001
Brugia malayi hypothetical protein 0.0194 0.0098 0.055
Brugia malayi hypothetical protein 0.0341 0.0185 0.1034
Echinococcus multilocularis aminopeptidase N 0.0302 0.0162 0.0907
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0246 0.0129 0.0723
Echinococcus granulosus rhodopsin orphan GPCR 0.0341 0.0185 0.1034
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0341 0.0185 0.1034
Echinococcus multilocularis purine nucleoside phosphorylase 0.0063 0.0022 0.0123
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0282 0.015 0.0842
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0404 0.0221 0.0221
Brugia malayi Metabotropic glutamate receptor precursor. 0.1069 0.0612 0.3426
Schistosoma mansoni Adenine phosphoribosyltransferase 0.0103 0.0045 0.0252
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0001 0.0001
Plasmodium falciparum plasmepsin IX 0.0038 0.0007 0.0007
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0103 0.0045 0.0252
Trypanosoma cruzi polyprenyl synthase, putative 0.0827 0.047 0.2631
Loa Loa (eye worm) hypothetical protein 0.0311 0.0167 0.0936
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0115 0.0052 0.0292
Echinococcus granulosus rhodopsin orphan GPCR 0.0341 0.0185 0.1034
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0053 0.0016 0.0089
Trypanosoma cruzi extracellular receptor, putative 0.0134 0.0063 0.0353
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0031 0.0003 0.0018
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0075 0.0029 0.016
Echinococcus granulosus expressed conserved protein 0.0037 0.0007 0.0037
Leishmania major polyprenyl synthase, putative 0.0827 0.047 0.2631
Echinococcus granulosus inosine guanosine and xanthosine phosphorylase 0.005 0.0014 0.008
Echinococcus multilocularis purine nucleoside phosphorylase 0.005 0.0014 0.008
Onchocerca volvulus 0.0302 0.0162 0.5317
Mycobacterium ulcerans adenine phosphoribosyltransferase 0.0103 0.0045 0.0045
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0082 0.0033 0.0186
Echinococcus granulosus 7tm_1 domain containing protein 0.0341 0.0185 0.1034
Loa Loa (eye worm) hypothetical protein 0.0341 0.0185 0.1035
Chlamydia trachomatis dihydrofolate reductase 0.0178 0.009 0.0059
Loa Loa (eye worm) G-protein coupled receptor 0.0341 0.0185 0.1035
Brugia malayi polk-prov protein 0.0026 0 0.0001

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 1700 nM Binding affinity as displacement of [3H]-5-HT binding to 5-hydroxytryptamine 6 receptor in HeLa cells. ChEMBL. 11689074
Ki (binding) = 1700 nM Binding affinity as displacement of [3H]-5-HT binding to 5-hydroxytryptamine 6 receptor in HeLa cells. ChEMBL. 11689074

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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