Detailed information for compound 26228

Basic information

Technical information
  • TDR Targets ID: 26228
  • Name: 2-adamantyl N-[4-[4-[(2-chlorophenyl)carbamoy lamino]butylamino]-2-(1H-indol-3-ylmethyl)-1, 4-dioxo-1-(phenethylamino)butan-2-yl]carbamat e
  • MW: 767.355 | Formula: C43H51ClN6O5
  • H donors: 6 H acceptors: 4 LogP: 6.86 Rotable bonds: 22
    Rule of 5 violations (Lipinski): 3
  • SMILES: O=C(Nc1ccccc1Cl)NCCCCNC(=O)CC(C(=O)NCCc1ccccc1)(Cc1c[nH]c2c1cccc2)NC(=O)OC1C2CC3CC1CC(C2)C3
  • InChi: 1S/C43H51ClN6O5/c44-35-13-5-7-15-37(35)49-41(53)47-18-9-8-17-45-38(51)26-43(25-33-27-48-36-14-6-4-12-34(33)36,40(52)46-19-16-28-10-2-1-3-11-28)50-42(54)55-39-31-21-29-20-30(23-31)24-32(39)22-29/h1-7,10-15,27,29-32,39,48H,8-9,16-26H2,(H,45,51)(H,46,52)(H,50,54)(H2,47,49,53)
  • InChiKey: MCGQZPBZSRMELE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-adamantyl N-[3-[4-[(2-chlorophenyl)carbamoylamino]butylamino]-1-(1H-indol-3-ylmethyl)-3-oxo-1-(phenethylcarbamoyl)propyl]carbamate
  • N-[3-[4-[[(2-chloroanilino)-oxomethyl]amino]butylamino]-1-(1H-indol-3-ylmethyl)-3-oxo-1-[oxo-(phenethylamino)methyl]propyl]carbamic acid 2-adamantyl ester
  • N-[3-[4-[(2-chlorophenyl)carbamoylamino]butylamino]-1-(1H-indol-3-ylmethyl)-3-keto-1-(phenethylcarbamoyl)propyl]carbamic acid 2-adamantyl ester
  • 2-adamantyl N-[4-[4-[(2-chlorophenyl)carbamoylamino]butylamino]-2-(1H-indol-3-ylmethyl)-1,4-dioxo-1-(2-phenylethylamino)butan-2-yl]carbamate
  • 2-adamantyl N-[3-[4-[(2-chlorophenyl)carbamoylamino]butylamino]-1-(1H-indol-3-ylmethyl)-3-oxo-1-(2-phenylethylcarbamoyl)propyl]carbamate
  • N-[3-[4-[[[(2-chlorophenyl)amino]-oxomethyl]amino]butylamino]-1-(1H-indol-3-ylmethyl)-3-oxo-1-[oxo-(2-phenylethylamino)methyl]propyl]carbamic acid 2-adamantyl ester
  • N-[3-[4-[(2-chlorophenyl)carbamoylamino]butylamino]-1-(1H-indol-3-ylmethyl)-3-keto-1-(2-phenylethylcarbamoyl)propyl]carbamic acid 2-adamantyl ester

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus cholecystokinin B receptor Starlite/ChEMBL References
Rattus norvegicus Cholecystokinin A receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132882 All targets in OG5_132882
Brugia malayi hypothetical protein Get druggable targets OG5_132882 All targets in OG5_132882
Brugia malayi sulfakinin receptor protein Get druggable targets OG5_132882 All targets in OG5_132882
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni amine GPCR Cholecystokinin A receptor   444 aa 412 aa 26.2 %
Schistosoma mansoni rhodopsin-like orphan GPCR Cholecystokinin A receptor   444 aa 380 aa 24.2 %
Schistosoma japonicum FMRFamide receptor, putative Cholecystokinin A receptor   444 aa 363 aa 21.2 %
Echinococcus multilocularis serotonin receptor Cholecystokinin A receptor   444 aa 468 aa 22.4 %
Echinococcus granulosus g protein coupled receptor Cholecystokinin A receptor   444 aa 399 aa 23.3 %
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Cholecystokinin A receptor   444 aa 364 aa 28.6 %
Echinococcus granulosus orexin receptor type 2 Cholecystokinin A receptor   444 aa 366 aa 23.5 %
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Cholecystokinin A receptor   444 aa 379 aa 24.8 %
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Cholecystokinin A receptor   444 aa 374 aa 24.6 %
Schistosoma japonicum ko:K04145 dopamine receptor D2, putative Cholecystokinin A receptor   444 aa 395 aa 24.6 %
Schistosoma mansoni biogenic amine (5HT) receptor Cholecystokinin A receptor   444 aa 362 aa 28.2 %
Echinococcus multilocularis g protein coupled receptor Cholecystokinin A receptor   444 aa 403 aa 24.1 %
Echinococcus granulosus rhodopsin orphan GPCR Cholecystokinin A receptor   444 aa 363 aa 19.6 %
Echinococcus multilocularis orexin receptor type 2 Cholecystokinin A receptor   444 aa 362 aa 22.4 %
Echinococcus multilocularis neuropeptides capa receptor Cholecystokinin A receptor   444 aa 400 aa 21.0 %
Echinococcus multilocularis g protein coupled receptor Cholecystokinin A receptor   444 aa 396 aa 23.2 %
Echinococcus granulosus g protein coupled receptor Cholecystokinin A receptor   444 aa 396 aa 23.5 %
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor Cholecystokinin A receptor   444 aa 383 aa 21.7 %
Onchocerca volvulus Cholecystokinin A receptor   444 aa 385 aa 28.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0036 0.011 0.0345
Echinococcus granulosus lysine specific demethylase 6a 0.0034 0.0097 0.0092
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0005 0.0000098037
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0005 0.0000098037
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0305 0.1928 0.1924
Onchocerca volvulus 0.0034 0.0095 0.0301
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0431 0.0991
Loa Loa (eye worm) helicase 0.0024 0.0031 0.0086
Trichomonas vaginalis malate dehydrogenase, putative 0.0215 0.1318 0.3161
Echinococcus multilocularis protein patched 0.0047 0.0182 0.0177
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0043 0.0104
Trichomonas vaginalis spermatogenesis associated factor, putative 0.0031 0.0077 0.0174
Echinococcus multilocularis Niemann Pick C1 protein 0.0155 0.0916 0.0912
Onchocerca volvulus 0.006 0.0269 0.0869
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0031 0.0114
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0064 0.0143
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.007 0.0338 0.0333
Plasmodium falciparum thioredoxin reductase 0.0051 0.0208 0.0654
Brugia malayi nuclear hormone receptor family member nhr-6 0.0041 0.0147 0.0463
Loa Loa (eye worm) hypothetical protein 0.0425 0.2736 0.892
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0005 0.0000098037
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0037 0.0115 0.0294
Onchocerca volvulus 0.006 0.0269 0.0869
Brugia malayi Inositol-1 0.004 0.0133 0.0419
Giardia lamblia Histone acetyltransferase GCN5 0.0085 0.044 0.094
Echinococcus granulosus chromobox protein 2 0.0024 0.0031 0.0026
Schistosoma mansoni DNA helicase recq5 0.004 0.0139 0.0134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0084 0.0191
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0635 0.4158 1
Entamoeba histolytica hypothetical protein 0.0024 0.0031 0.0075
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0041 0.0147 0.0142
Echinococcus multilocularis lysosomal alpha glucosidase 0.0354 0.2259 0.2255
Echinococcus multilocularis sterol regulatory element binding protein 0.0047 0.0182 0.0177
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0032 0.0083 0.0079
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0656 0.4301 1
Entamoeba histolytica hypothetical protein 0.0038 0.0126 0.0304
Brugia malayi ecdysone receptor 0.0041 0.0147 0.0463
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0143 0.0836 0.201
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0191 0.046
Mycobacterium ulcerans pyruvate kinase 0.0037 0.0115 0.0294
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0305 0.03
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0397 0.0912
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0088 0.046 0.0456
Entamoeba histolytica recQ family DNA helicase 0.0021 0.0005 0.0013
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0031 0.0063
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0005 0.0000098037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0088 0.046 0.1487
Trypanosoma cruzi metacaspase, putative 0.0047 0.0186 0.0421
Echinococcus granulosus lamin dm0 0.0059 0.0262 0.0258
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0086
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0108 0.0376
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0098 0.0527 0.1911
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0635 0.4158 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0354 0.2259 0.7361
Brugia malayi sulfakinin receptor protein 0.0269 0.1683 0.548
Mycobacterium tuberculosis Conserved hypothetical protein 0.0389 0.2493 1
Brugia malayi Cytochrome P450 family protein 0.0052 0.0219 0.0699
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0029 0.0064 0.0137
Echinococcus multilocularis L lactate dehydrogenase 0.0236 0.1463 0.1459
Loa Loa (eye worm) hypothetical protein 0.0088 0.046 0.1487
Echinococcus multilocularis expressed protein 0.0399 0.2564 0.256
Trypanosoma brucei metacaspase 5, putative 0.0047 0.0186 0.043
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0084 0.0431 0.1392
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.004 0.0139 0.0489
Brugia malayi Nuclear hormone receptor-like 1 0.0046 0.018 0.0572
Trypanosoma cruzi cruzipain precursor, putative 0.0068 0.0327 0.075
Plasmodium falciparum malate dehydrogenase 0.0425 0.2736 1
Echinococcus granulosus neuropeptide receptor A26 0.1012 0.6707 0.6705
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0079 0.0397 0.0945
Echinococcus multilocularis neuropeptide receptor A26 0.1012 0.6707 0.6705
Onchocerca volvulus Putative organic anion transporter 0.006 0.0269 0.0869
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0077 0.0174
Loa Loa (eye worm) DR-78 0.0041 0.0147 0.0463
Trichomonas vaginalis aldo-keto reductase, putative 0.0034 0.0095 0.0218
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0047 0.0182 0.0577
Echinococcus multilocularis RUN 0.0085 0.0441 0.0436
Loa Loa (eye worm) hypothetical protein 0.0041 0.0141 0.0446
Loa Loa (eye worm) heterochromatin protein 1 0.0087 0.0452 0.1461
Echinococcus granulosus pyruvate kinase 0.0037 0.0115 0.011
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0041 0.0147 0.0469
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0005 0.0000098037
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0088 0.046 0.1487
Schistosoma mansoni hypothetical protein 0.0368 0.2355 0.2351
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0215 0.1318 0.3161
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0411 0.264 0.2636
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0034 0.0095 0.0091
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0133 0.0298
Loa Loa (eye worm) hypothetical protein 0.0026 0.0043 0.0125
Trichomonas vaginalis aldo-keto reductase, putative 0.0034 0.0095 0.0218
Schistosoma mansoni hypothetical protein 0.0038 0.0126 0.0122
Mycobacterium ulcerans DNA polymerase IV 0.0065 0.0303 0.1058
Trypanosoma brucei mitochondrial malate dehydrogenase 0.0208 0.1269 0.2949
Echinococcus granulosus agrin 0.0041 0.0141 0.0137
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0031 0.0063
Schistosoma mansoni phosphatidylserine receptor 0.0034 0.0097 0.0092
Echinococcus multilocularis chromobox protein 2 0.0024 0.0031 0.0026
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0656 0.4301 1
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0126 0.0122
Onchocerca volvulus 0.0034 0.0095 0.0301
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0191 0.0441
Trypanosoma brucei unspecified product 0.0025 0.0035 0.0078
Brugia malayi jmjC domain containing protein 0.0034 0.0097 0.03
Brugia malayi Glycosyl hydrolases family 31 protein 0.0029 0.0064 0.0193
Brugia malayi sodium-independent organic anion transporter family protein 0.006 0.0269 0.0864
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.031 0.1963 0.7836
Leishmania major alpha glucosidase II subunit, putative 0.0079 0.0397 0.0831
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0102 0.0225
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0186 0.0436
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.004 0.0139 0.0398
Schistosoma mansoni hypothetical protein 0.0045 0.017 0.0165
Echinococcus granulosus RUN 0.0085 0.0441 0.0436
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0191 0.0186
Brugia malayi MH2 domain containing protein 0.0128 0.0729 0.2365
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0005 0.0000098037
Echinococcus multilocularis pyruvate kinase 0.0029 0.0063 0.0058
Loa Loa (eye worm) hypothetical protein 0.0059 0.0262 0.0841
Echinococcus multilocularis apoptotic protease activating factor 1 0.0044 0.0164 0.0159
Loa Loa (eye worm) intermediate filament protein 0.0059 0.0262 0.0841
Entamoeba histolytica hypothetical protein 0.0021 0.0005 0.0012
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0029 0.0064 0.0137
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.002 0.0043
Schistosoma mansoni zinc finger protein 0.0041 0.0147 0.0142
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0186 0.0436
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0042 0.0151 0.0553
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0088 0.046 0.1487
Trichomonas vaginalis DNA-3-methyladenine glycosylase, putative 0.0236 0.146 0.3504
Brugia malayi jmjC domain containing protein 0.0034 0.0097 0.03
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0043 0.0074
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0115 0.0361
Schistosoma mansoni jumonji domain containing protein 0.0128 0.073 0.0726
Loa Loa (eye worm) oxidoreductase 0.0034 0.0095 0.0296
Loa Loa (eye worm) thioredoxin reductase 0.0051 0.0208 0.0664
Entamoeba histolytica aldose reductase, putative 0.0034 0.0095 0.0229
Brugia malayi Bromodomain containing protein 0.0091 0.0481 0.1555
Onchocerca volvulus 0.0205 0.125 0.4071
Echinococcus granulosus Solute carrier organic anion transporter family 0.006 0.0269 0.0265
Trichomonas vaginalis malate dehydrogenase, putative 0.0215 0.1318 0.3161
Echinococcus granulosus pyruvate kinase 0.0037 0.0115 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0031 0.0063
Brugia malayi Flap endonuclease-1 0.0028 0.0055 0.0162
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0041 0.0141 0.0446
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.0208 0.1269 0.2942
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0031 0.0075
Giardia lamblia Kinesin-5 0.0028 0.0059 0.001
Trichomonas vaginalis malate dehydrogenase, putative 0.0215 0.1318 0.3161
Schistosoma mansoni lipoxygenase 0.0305 0.1928 0.1924
Trypanosoma brucei ISWI complex protein 0.0033 0.0091 0.0209
Schistosoma mansoni hypothetical protein 0.0045 0.017 0.0165
Schistosoma mansoni L-lactate dehydrogenase 0.0425 0.2736 0.2733
Echinococcus granulosus histone acetyltransferase KAT2B 0.0306 0.1935 0.1931
Brugia malayi steroid hormone receptor 0.0088 0.046 0.1487
Wolbachia endosymbiont of Brugia malayi DNA polymerase III alpha subunit 0.0228 0.1404 0.4881
Loa Loa (eye worm) hypothetical protein 0.0091 0.0484 0.1564
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0029 0.0064 0.0154
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.031 0.1963 0.7836
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0055 0.0162
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0867 0.5726 0.5724
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0133 0.0211
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0088 0.046 0.0456
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0034 0.0095 0.0343
Trypanosoma cruzi cytosolic malate dehydrogenase, putative 0.0215 0.1318 0.3055
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0327 0.075
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0024 0.0031 0.0086
Schistosoma mansoni hypothetical protein 0.0191 0.1155 0.1151
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0141 0.0819 0.0815
Toxoplasma gondii lactate dehydrogenase LDH2 0.0425 0.2736 1
Toxoplasma gondii aldose reductase, putative 0.0034 0.0095 0.033
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0005 0.0000098037
Leishmania major mitochondrial malate dehydrogenase 0.0208 0.1269 0.2879
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0311 0.1965 0.4514
Treponema pallidum fructose-bisphosphate aldolase 0.0635 0.4158 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0036 0.011 0.0106
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0191 0.0347
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0133 0.0129
Brugia malayi hypothetical protein 0.0121 0.0681 0.221
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0041 0.0141 0.0499
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0143 0.0836 0.0831
Echinococcus granulosus geminin 0.0368 0.2355 0.2351
Brugia malayi orphan nuclear receptor NR2E1 0.0041 0.0147 0.0463
Loa Loa (eye worm) hypothetical protein 0.0339 0.2159 0.7034
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0079 0.024
Plasmodium vivax lactate dehydrogenase 0.0425 0.2736 1
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0005 0.0000098037
Schistosoma mansoni pyruvate kinase 0.0037 0.0115 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0236 0.146 0.3504
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0125 0.0288
Loa Loa (eye worm) hypothetical protein 0.0088 0.046 0.1487
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0134 0.0309
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0128 0.0733 0.2814
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0303 0.0701
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0097 0.03
Plasmodium falciparum cell division cycle protein 48 homologue, putative 0.003 0.0066 0.013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0042 0.0089
Echinococcus granulosus Nuclear hormone receptor HR96 0.0041 0.0147 0.0142
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0635 0.4158 1
Leishmania major trypanothione reductase 0.0051 0.0208 0.0387
Brugia malayi sodium-independent organic anion transporter family protein 0.006 0.0269 0.0864
Brugia malayi Niemann-Pick C1 protein precursor 0.0109 0.0601 0.1946
Plasmodium falciparum JmjC domain-containing protein, putative 0.0034 0.0097 0.0242
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0041 0.0147 0.0463
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0049 0.0177
Brugia malayi Bromodomain containing protein 0.0174 0.1044 0.3393
Schistosoma mansoni cell division control protein 48 aaa family protein 0.0031 0.0077 0.0072
Leishmania major cathepsin L-like protease 0.0068 0.0327 0.0667
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0066 0.0148
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0128 0.0733 0.3639
Wolbachia endosymbiont of Brugia malayi phosphoglyceromutase 0.0107 0.0588 0.1748
Loa Loa (eye worm) CHromoDomain protein family member 0.0032 0.0083 0.0256
Echinococcus multilocularis Solute carrier organic anion transporter family 0.006 0.0269 0.0265
Echinococcus granulosus kinesin family 1 0.0219 0.1347 0.1343
Trypanosoma cruzi metacaspase 5, putative 0.0047 0.0186 0.0421
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0079 0.0397 0.1282
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0034 0.0097 0.0092
Brugia malayi nuclear hormone receptor 0.0088 0.046 0.1487
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0115 0.0361
Trypanosoma cruzi aldo-keto reductase 0.0034 0.0095 0.0209
Trichomonas vaginalis aldo-keto reductase, putative 0.0034 0.0095 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.006 0.0134
Onchocerca volvulus Huntingtin homolog 0.0131 0.0752 0.2444
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0327 0.0758
Echinococcus granulosus aldo keto reductase 0.0034 0.0095 0.0091
Loa Loa (eye worm) runx1 0.0059 0.0268 0.0859
Echinococcus granulosus L lactate dehydrogenase 0.0236 0.1463 0.1459
Schistosoma mansoni survival motor neuron protein 0.0053 0.0226 0.0221
Loa Loa (eye worm) hypothetical protein 0.0088 0.046 0.1487
Onchocerca volvulus 0.0085 0.0441 0.1429
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0191 0.0448
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0041 0.0146 0.0515
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0327 0.0758
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0066 0.0148
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0034 0.0095 0.0091
Schistosoma mansoni microtubule-associated protein tau 0.15 1 1
Onchocerca volvulus 0.0044 0.0164 0.0526
Echinococcus granulosus aldehyde reductase 0.0024 0.0029 0.0024
Schistosoma mansoni rab6-interacting 0.0085 0.0441 0.0436
Loa Loa (eye worm) hypothetical protein 0.0058 0.0255 0.0818
Trypanosoma brucei pyruvate kinase 1 0.0037 0.0115 0.0265
Trypanosoma brucei unspecified product 0.0058 0.0255 0.059
Schistosoma mansoni polycystin 1-related 0.0085 0.0441 0.0436
Trypanosoma cruzi Valosin-containing protein, putative 0.003 0.0066 0.0142
Echinococcus multilocularis geminin 0.0368 0.2355 0.2351
Mycobacterium ulcerans putative regulatory protein 0.0039 0.0127 0.034
Schistosoma mansoni single-minded 0.0052 0.0218 0.0213
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0055 0.0131
Brugia malayi Pre-SET motif family protein 0.0033 0.0091 0.0282
Echinococcus multilocularis protein dispatched 1 0.0053 0.0226 0.0221
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0125 0.0288
Loa Loa (eye worm) hypothetical protein 0.006 0.0269 0.0864
Echinococcus granulosus ubiquitin specific protease 41 0.0084 0.0431 0.0426
Schistosoma mansoni hypothetical protein 0.0298 0.188 0.1876
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0298 0.188 0.6125
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0125 0.0278
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.006 0.0134
Brugia malayi SPARC precursor 0.0041 0.0141 0.0446
Loa Loa (eye worm) hypothetical protein 0.0048 0.0189 0.0603
Trichomonas vaginalis chromobox protein, putative 0.0087 0.0452 0.1077
Echinococcus multilocularis aldo keto reductase 0.0034 0.0095 0.0091
Entamoeba histolytica 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0107 0.0588 0.1414
Plasmodium falciparum LCCL domain-containing protein 0.0085 0.0441 0.1515
Giardia lamblia Sgs1 DNA helicase, putative 0.004 0.0139 0.0206
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0055 0.005
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0031 0.0075
Schistosoma mansoni inositol monophosphatase 0.004 0.0133 0.0128
Echinococcus granulosus histone acetyltransferase KAT2B 0.0098 0.0527 0.0523
Trypanosoma cruzi aldo/keto reductase, putative 0.0034 0.0095 0.0209
Mycobacterium ulcerans DNA polymerase IV 0.0065 0.0303 0.1058
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.0305 0.1098
Loa Loa (eye worm) hypothetical protein 0.006 0.0269 0.0864
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0034 0.0095 0.0091
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0046 0.018 0.0573
Loa Loa (eye worm) hypothetical protein 0.0046 0.018 0.0573
Brugia malayi sodium-independent organic anion transporter family protein 0.006 0.0269 0.0864
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0031 0.0075
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0305 0.1069
Schistosoma mansoni methyl-cpg binding protein mbd 0.0037 0.0117 0.0112
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0046 0.018 0.0175
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0088 0.046 0.1487
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0231 0.0544
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0108 0.0248
Entamoeba histolytica hypothetical protein 0.0038 0.0126 0.0304
Treponema pallidum DNA polymerase III subunit alpha 0.0228 0.1404 0.3367
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0102 0.0225
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0005 0.0000098037
Onchocerca volvulus 0.0041 0.0147 0.0469
Leishmania major Transitional endoplasmic reticulum ATPase, putative,valosin-containing protein homolog 0.003 0.0066 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0108 0.0248
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0034 0.0095 0.0091
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0079 0.0397 0.0945
Trypanosoma cruzi DNA polymerase kappa, putative 0.0065 0.0303 0.0692
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0043 0.0158 0.027
Trichomonas vaginalis malate dehydrogenase, putative 0.0118 0.0665 0.1589
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0115 0.0361
Loa Loa (eye worm) hypothetical protein 0.0041 0.0147 0.0463
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0327 0.0758
Trichomonas vaginalis DNA polymerase eta, putative 0.0065 0.0303 0.0717
Leishmania major mitochondrial DNA polymerase beta 0.0656 0.4301 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0128 0.0733 0.2814
Schistosoma mansoni pol-related 0.0034 0.0095 0.009
Brugia malayi tailless protein 0.0041 0.0147 0.0463
Trichomonas vaginalis aldo/keto reductase, putative 0.0034 0.0095 0.0218
Echinococcus multilocularis Chromo domain 0.0024 0.0031 0.0026
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0035 0.0102 0.0245
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0431 0.0991
Toxoplasma gondii peptidylprolyl isomerase 0.0035 0.0102 0.0354
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0327 0.0758
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0053 0.0224 0.0715
Echinococcus multilocularis microtubule associated protein 2 0.15 1 1
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0191 0.0441
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0024 0.0031 0.00000000041549
Mycobacterium leprae POSSIBLE 3-METHYLADENINE DNA GLYCOSYLASE MPG 0.012 0.0676 0.3344
Brugia malayi Pyruvate kinase, muscle isozyme 0.0037 0.0115 0.036
Loa Loa (eye worm) hypothetical protein 0.0033 0.0088 0.027
Echinococcus granulosus neutral alpha glucosidase AB 0.0079 0.0397 0.0393
Loa Loa (eye worm) hypothetical protein 0.0041 0.0147 0.0463
Leishmania major hypothetical protein, conserved 0.0027 0.0049 0.0012
Trichomonas vaginalis malate dehydrogenase, putative 0.0215 0.1318 0.3161
Loa Loa (eye worm) hypothetical protein 0.0036 0.011 0.0345
Brugia malayi Pyruvate kinase, M2 isozyme 0.0037 0.0115 0.036
Trypanosoma brucei trypanothione reductase 0.0051 0.0208 0.0481
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0031 0.0063
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0005 0.0000098037
Plasmodium falciparum pyruvate kinase 0.0037 0.0115 0.0311
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0088 0.046 0.1487
Echinococcus granulosus lysosomal alpha glucosidase 0.0354 0.2259 0.2255
Echinococcus granulosus lipoxygenase domain containing protein 0.0085 0.0441 0.0436
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0108 0.0248
Entamoeba histolytica hypothetical protein 0.0024 0.0031 0.0075
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0191 0.046
Echinococcus multilocularis neutral alpha glucosidase AB 0.0079 0.0397 0.0393
Echinococcus multilocularis lactate dehydrogenase a 0.0425 0.2736 0.2733
Toxoplasma gondii protease inhibitor PI2 0.0041 0.0141 0.0499
Echinococcus granulosus Niemann Pick C1 protein 0.0109 0.0601 0.0596
Echinococcus granulosus methyl CpG binding domain protein 2 0.0037 0.0117 0.0112
Giardia lamblia Malate dehydrogenase 0.0215 0.1318 0.3078
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0305 0.1069
Brugia malayi nuclear receptor NHR-88 0.0088 0.046 0.1487
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0079 0.0397 0.0955
Onchocerca volvulus Putative organic anion transporter 0.006 0.0269 0.0869
Echinococcus granulosus cytosolic malate dehydrogenase 0.0215 0.1318 0.1314
Trichomonas vaginalis aldo-keto reductase, putative 0.0034 0.0095 0.0218
Entamoeba histolytica hypothetical protein 0.0038 0.0126 0.0304
Trichomonas vaginalis alpha-glucosidase, putative 0.0079 0.0397 0.0945
Echinococcus multilocularis tumor protein p63 0.0361 0.2308 0.2304
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0041 0.0141 0.0446
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0635 0.4158 1
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0125 0.0711 0.0707
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0041 0.0147 0.0142
Onchocerca volvulus 0.0026 0.0043 0.0132
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0186 0.0436
Trypanosoma cruzi ISWI complex protein 0.0033 0.0091 0.02
Brugia malayi nuclear hormone receptor 0.0041 0.0147 0.0463
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0327 0.075
Trichomonas vaginalis malate dehydrogenase, putative 0.0215 0.1318 0.3161
Loa Loa (eye worm) hypothetical protein 0.0121 0.0681 0.221
Echinococcus granulosus aldo keto reductase 0.0034 0.0095 0.0091
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0186 0.0436
Brugia malayi ImpB/MucB/SamB family protein 0.0036 0.011 0.0345
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0057 0.0053
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0005 0.0000098037
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0088 0.046 0.0456
Plasmodium falciparum histone acetyltransferase GCN5 0.0085 0.044 0.1512
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0043 0.0104
Echinococcus granulosus thioredoxin glutathione reductase 0.0051 0.0208 0.0203
Trichomonas vaginalis malate dehydrogenase, putative 0.0215 0.1318 0.3161
Brugia malayi hypothetical protein 0.0044 0.0164 0.052
Echinococcus multilocularis malate dehydrogenase 0.0208 0.1269 0.1265
Onchocerca volvulus 0.0041 0.0141 0.0452
Echinococcus granulosus cytosolic malate dehydrogenase 0.0215 0.1318 0.1314
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0078 0.0394 0.0389
Trypanosoma cruzi DNA polymerase kappa, putative 0.0065 0.0303 0.0692
Onchocerca volvulus 0.006 0.0269 0.0869
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0049 0.0158
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0035 0.0102 0.0234
Trypanosoma brucei Metacaspase-4 0.0047 0.0186 0.043
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0002
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0055 0.0199
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0215 0.1318 0.3161
Toxoplasma gondii thioredoxin reductase 0.0051 0.0208 0.0742
Echinococcus multilocularis aldo keto reductase 0.0034 0.0095 0.0091
Trypanosoma brucei glycosyl hydrolase-like protein 0.0029 0.0064 0.0146
Trypanosoma brucei DNA polymerase eta, putative 0.0036 0.011 0.0254
Entamoeba histolytica deoxycytidyl transferase, putative 0.0036 0.011 0.0265
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0079 0.0241
Loa Loa (eye worm) hypothetical protein 0.006 0.0269 0.0864
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0031 0.0063
Loa Loa (eye worm) hypothetical protein 0.0088 0.046 0.1487
Brugia malayi hypothetical protein 0.0131 0.0752 0.2439
Brugia malayi Heterochromatin protein 1 0.0087 0.0452 0.1461
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0036 0.0108 0.0336
Brugia malayi Valyl-tRNA synthetase 0.0024 0.0031 0.0086
Schistosoma mansoni intermediate filament proteins 0.0059 0.0262 0.0258
Onchocerca volvulus 0.0058 0.0256 0.0826
Echinococcus granulosus dnaJ subfamily B 0.0889 0.5873 0.5871
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0088 0.046 0.1487
Loa Loa (eye worm) hypothetical protein 0.0041 0.0147 0.0463
Brugia malayi CXXC zinc finger family protein 0.0062 0.0288 0.0925
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0133 0.0309
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0031 0.0063
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0064 0.0143
Brugia malayi hypothetical protein 0.0474 0.3067 1
Entamoeba histolytica cdc48-like protein, putative 0.003 0.0066 0.016
Loa Loa (eye worm) nuclear hormone receptor 0.0041 0.0147 0.0463
Toxoplasma gondii transporter, major facilitator family protein 0.006 0.0269 0.0967
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0096 0.0516 0.0511
Onchocerca volvulus 0.0059 0.0262 0.0847
Trypanosoma brucei glycosomal malate dehydrogenase 0.0208 0.1269 0.2949
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0034 0.0097 0.0335
Trypanosoma brucei unspecified product 0.0025 0.0035 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0431 0.1026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0191 0.0448
Echinococcus granulosus sterol regulatory element binding protein 0.0047 0.0182 0.0177
Loa Loa (eye worm) agrin synaptic family protein 0.0041 0.0141 0.0446
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0034 0.0095 0.0122
Onchocerca volvulus 0.0085 0.0441 0.1429
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0005 0.0000098037
Echinococcus granulosus Niemann Pick C1 protein 0.0155 0.0916 0.0912
Loa Loa (eye worm) apoptosis regulator protein 0.0298 0.188 0.6125
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0034 0.0095 0.0091
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0084 0.0431 0.0917
Schistosoma mansoni aryl hydrocarbon receptor 0.0052 0.0218 0.0213
Brugia malayi bHLH-PAS transcription factor 0.0039 0.0127 0.0397
Plasmodium vivax kinesin-5 0.0028 0.0059 0.0215
Trypanosoma brucei metacaspase MCA3 0.0047 0.0186 0.043
Brugia malayi Thioredoxin reductase 0.0051 0.0208 0.0663
Loa Loa (eye worm) hypothetical protein 0.0046 0.018 0.0573
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0088 0.046 0.1487
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0091 0.0087
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0041 0.0141 0.0499
Loa Loa (eye worm) hypothetical protein 0.0041 0.0147 0.0463
Onchocerca volvulus 0.0034 0.0095 0.0301
Echinococcus multilocularis thioredoxin glutathione reductase 0.0051 0.0208 0.0203
Onchocerca volvulus Cell death protein 3 homolog 0.0091 0.0484 0.1569
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0086
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0059 0.0262 0.0841
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0084 0.0431 0.0426
Schistosoma mansoni steroid hormone receptor ad4bp 0.0088 0.046 0.0456
Schistosoma mansoni niemann-pick C1 (NPC1) 0.011 0.0612 0.0608
Echinococcus granulosus malate dehydrogenase 0.0208 0.1269 0.1265
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.006 0.0269 0.0265
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0088 0.046 0.0456
Plasmodium vivax JmjC domain containing protein 0.0034 0.0097 0.0353
Entamoeba histolytica hypothetical protein 0.0021 0.0005 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0186 0.0436
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0084 0.0431 0.1036
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.007 0.0338 0.1202
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0084 0.0431 0.0426
Echinococcus multilocularis Protein lozenge 0.0059 0.0268 0.0263
Echinococcus multilocularis ubiquitin specific protease 41 0.0084 0.0431 0.0426
Brugia malayi Steroid receptor seven-up type 2 0.0088 0.046 0.1487
Schistosoma mansoni caspase-7 (C14 family) 0.0125 0.0711 0.0707
Loa Loa (eye worm) hypothetical protein 0.0154 0.0905 0.294
Brugia malayi Nuclear hormone receptor E75 0.0041 0.0147 0.0463
Entamoeba histolytica pyruvate kinase, putative 0.0026 0.004 0.0096
Onchocerca volvulus Transitional endoplasmic reticulum ATPase homolog 0.0031 0.0077 0.0243
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0041 0.0088
Mycobacterium tuberculosis Probable reductase 0.0115 0.0646 0.2459
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0133 0.0307
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0186 0.0662
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0036 0.011 0.0106
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0088 0.046 0.0456
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0037 0.0117 0.0112
Echinococcus multilocularis pyruvate kinase 0.0037 0.0115 0.011
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.004 0.0139 0.0489
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0041 0.0147 0.0142
Trichomonas vaginalis hypothetical protein 0.0024 0.0031 0.0063
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0005 0.0000098037
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.007 0.0338 0.1202
Brugia malayi Nuclear hormone receptor-like 1 0.0088 0.046 0.1487
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0049 0.0064
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0125 0.0711 0.0707
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0092 0.049 0.1137
Schistosoma mansoni alpha-glucosidase 0.0305 0.1926 0.1922
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0108 0.0248
Brugia malayi hypothetical protein 0.0085 0.0441 0.1424
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE1 (DNA nucleotidyltransferase) 0.0229 0.1412 0.5585
Loa Loa (eye worm) hypothetical protein 0.0131 0.0752 0.2439
Leishmania major prostaglandin f synthase, putative 0.0034 0.0095 0.0122
Onchocerca volvulus 0.006 0.0269 0.0869
Loa Loa (eye worm) hypothetical protein 0.0269 0.1683 0.5481
Schistosoma mansoni nuclear receptor 0.0041 0.0147 0.0142
Schistosoma mansoni zinc finger protein 0.0033 0.0091 0.0086
Leishmania major malate dehydrogenase, putative 0.0425 0.2736 0.6324
Trypanosoma cruzi ISWI complex protein 0.0033 0.0091 0.02
Mycobacterium ulcerans DNA polymerase III subunit alpha 0.0228 0.1404 0.5553
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0041 0.0141 0.0446
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0034 0.0095 0.0122
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.007 0.0338 0.1202
Loa Loa (eye worm) hypothetical protein 0.0027 0.005 0.0148
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0311 0.1965 0.4567
Onchocerca volvulus Protein ultraspiracle homolog 0.0088 0.046 0.1493
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0303 0.0701
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0398 0.0394
Echinococcus multilocularis nuclear receptor nhr 48 0.0041 0.0147 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0088 0.046 0.1487
Plasmodium falciparum metacaspase 1 0.0047 0.0186 0.0572
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0108 0.0248
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0049 0.011
Entamoeba histolytica aldose reductase, putative 0.0034 0.0095 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0031 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0082 0.0189
Schistosoma mansoni loxhd1 0.0085 0.0441 0.0436
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0108 0.0248
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0147 0.0142
Onchocerca volvulus 0.0062 0.0288 0.0931
Schistosoma mansoni lipoxygenase 0.0152 0.0894 0.089
Trichomonas vaginalis DNA helicase recq, putative 0.0068 0.0323 0.0766
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0079 0.0397 0.0955
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0298 0.188 0.1876
Schistosoma mansoni malate dehydrogenase 0.0208 0.1269 0.1265
Schistosoma mansoni chromobox protein 0.0024 0.0031 0.0026
Echinococcus granulosus jumonji domain containing 1A 0.0034 0.0097 0.0092
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0034 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0041 0.0147 0.0463
Loa Loa (eye worm) hypothetical protein 0.007 0.0342 0.11
Loa Loa (eye worm) hypothetical protein 0.0088 0.046 0.1487
Trypanosoma cruzi glycosomal malate dehydrogenase, putative 0.0208 0.1269 0.2942
Schistosoma mansoni hypothetical protein 0.0298 0.188 0.1876
Loa Loa (eye worm) PHD-finger family protein 0.0045 0.0169 0.0537
Schistosoma mansoni retinoic acid receptor RXR 0.0088 0.046 0.0456
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0128 0.073 0.0726
Echinococcus granulosus caspase 0.0125 0.0711 0.0707
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0141 0.0819 0.0815
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0354 0.2259 0.7361
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.007 0.0342 0.0337
Entamoeba histolytica malate dehydrogenase,cytoplasmic, putative 0.0215 0.1318 0.3169
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0128 0.073 0.0726
Onchocerca volvulus 0.0039 0.0127 0.0403
Onchocerca volvulus 0.0033 0.0088 0.0276
Schistosoma mansoni cpg binding protein 0.007 0.034 0.0335
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0158 0.0365
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.0255 0.059
Loa Loa (eye worm) hypothetical protein 0.0034 0.0097 0.03
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0127 0.0293
Brugia malayi Probable malate dehydrogenase, mitochondrial precursor 0.0208 0.1269 0.4129
Brugia malayi PHD-finger family protein 0.0065 0.0308 0.0991
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0005 0.0000098037
Loa Loa (eye worm) RecQ helicase 0.0068 0.0323 0.1039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0125 0.0288
Brugia malayi Malate dehydrogenase, cytoplasmic 0.0215 0.1318 0.4288
Leishmania major hypothetical protein, conserved 0.0034 0.0097 0.0126
Loa Loa (eye worm) pyruvate kinase-PB 0.0026 0.004 0.0115
Plasmodium falciparum metacaspase-like protein 0.0047 0.0186 0.0572
Brugia malayi CHD4 protein 0.0032 0.0083 0.0256
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0041 0.0147 0.0469
Trichomonas vaginalis alpha-glucosidase, putative 0.0079 0.0397 0.0945
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0005 0.0000098037
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0088 0.046 0.0456
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0305 0.1928 0.1924
Plasmodium vivax malate dehydrogenase, putative 0.0425 0.2736 1
Loa Loa (eye worm) bromodomain containing protein 0.0046 0.0178 0.0565
Trichomonas vaginalis aldo-keto reductase, putative 0.0034 0.0095 0.0218
Trichomonas vaginalis set domain proteins, putative 0.0255 0.1587 0.381
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0208 0.0472
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0088 0.046 0.1487
Toxoplasma gondii kinesin motor domain-containing protein 0.0028 0.0059 0.0196
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0327 0.0758
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0327 0.0758
Schistosoma mansoni malate dehydrogenase 0.0215 0.1318 0.1313
Onchocerca volvulus 0.0121 0.0681 0.2212
Echinococcus multilocularis lysine specific demethylase 5A 0.0128 0.073 0.0726
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0115 0.0646 0.2459
Trypanosoma brucei cytosolic malate dehydrogenase 0.0215 0.1318 0.3062
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0042 0.0149 0.0144
Brugia malayi hypothetical protein 0.0027 0.0049 0.0142
Loa Loa (eye worm) doublecortin family protein 0.0085 0.0441 0.1424
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0082 0.0189
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0046 0.018 0.0175
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0127 0.0293
Mycobacterium ulcerans error-prone DNA polymerase 0.0228 0.1404 0.5553
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0049 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0031 0.0063
Loa Loa (eye worm) jmjC domain-containing protein 0.0136 0.0782 0.2539
Chlamydia trachomatis malate dehydrogenase 0.0215 0.1318 0.9332
Echinococcus multilocularis lamin dm0 0.0059 0.0262 0.0258
Echinococcus granulosus L lactate dehydrogenase B chain 0.0425 0.2736 0.2733
Schistosoma mansoni jumonji domain containing protein 0.0034 0.0097 0.0092
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.007 0.0338 0.1087
Echinococcus multilocularis lipoxygenase domain containing protein 0.0085 0.0441 0.0436
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.007 0.0338 0.0333
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0041 0.0141 0.0499
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0082 0.0187
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0034 0.0095 0.0091
Echinococcus multilocularis chromobox protein 1 0.0087 0.0452 0.0448
Schistosoma mansoni cpg binding protein 0.007 0.034 0.0335
Echinococcus multilocularis lysine specific demethylase 6a 0.0034 0.0097 0.0092
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0043 0.0125
Echinococcus granulosus tumor protein p63 0.0361 0.2308 0.2304
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0084 0.0431 0.1026
Loa Loa (eye worm) hypothetical protein 0.0027 0.005 0.0148
Echinococcus multilocularis dnaJ subfamily B 0.0889 0.5873 0.5871
Schistosoma mansoni hypothetical protein 0.0045 0.017 0.0165
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0057 0.0252 0.0814
Plasmodium falciparum L-lactate dehydrogenase 0.0425 0.2736 1
Echinococcus granulosus neuropeptide s receptor 0.1012 0.6707 0.6705
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0143 0.0836 0.1941
Echinococcus multilocularis expressed protein 0.0041 0.0141 0.0137
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0034 0.0095 0.0295
Mycobacterium ulcerans hypothetical protein 0.0389 0.2493 1
Echinococcus multilocularis lactate dehydrogenase protein 0.0425 0.2736 0.2733
Loa Loa (eye worm) hypothetical protein 0.0104 0.0569 0.1842
Echinococcus multilocularis caspase 2 0.0091 0.0484 0.0479
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0032 0.0083 0.0079
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0034 0.0095 0.0091
Onchocerca volvulus Huntingtin homolog 0.0131 0.0752 0.2444
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0088 0.046 0.1487
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0041 0.0141 0.0446
Loa Loa (eye worm) hypothetical protein 0.0088 0.046 0.1487
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0135 0.0776 0.0772
Echinococcus multilocularis Polycystic kidney disease protein 0.0085 0.0441 0.0436
Schistosoma mansoni zinc finger protein 0.0054 0.023 0.0225
Echinococcus multilocularis dna polymerase kappa 0.0065 0.0303 0.0298
Loa Loa (eye worm) hypothetical protein 0.0084 0.0431 0.1392
Schistosoma mansoni DNA polymerase eta 0.0036 0.011 0.0106
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0055 0.0124
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.007 0.0342 0.0337
Brugia malayi Protein cec-1. 0.0024 0.0031 0.0086
Loa Loa (eye worm) hypothetical protein 0.0041 0.0147 0.0463
Echinococcus multilocularis agrin 0.0041 0.0141 0.0137
Schistosoma mansoni hypothetical protein 0.0368 0.2355 0.2351
Mycobacterium leprae PROBABLE MALATE DEHYDROGENASE MDH 0.0215 0.1318 0.6664
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0186 0.0436
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0034 0.0095 0.0295
Leishmania major cathepsin L-like protease 0.0068 0.0327 0.0667
Brugia malayi intermediate filament protein 0.0059 0.0262 0.0841
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0034 0.0095 0.0091
Leishmania major cathepsin L-like protease 0.0068 0.0327 0.0667
Loa Loa (eye worm) nuclear receptor NHR-67 0.0041 0.0147 0.0463
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0088 0.046 0.1487
Brugia malayi hypothetical protein 0.0261 0.163 0.5308
Leishmania major pyruvate kinase 0.0037 0.0115 0.0169
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0054 0.0231 0.0744
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0186 0.0436
Trichomonas vaginalis malate dehydrogenase, putative 0.0188 0.114 0.2732
Echinococcus multilocularis lactate dehydrogenase a 0.0425 0.2736 0.2733
Mycobacterium tuberculosis Probable oxidoreductase 0.0034 0.0095 0.0212
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0088 0.046 0.0456
Brugia malayi conserved hypotetical protein 0.0041 0.0147 0.0463
Schistosoma mansoni protein phosphatase 2C 0.0034 0.0097 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0182 0.0425
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0226 0.0723
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0088 0.046 0.1487
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0043 0.0125
Brugia malayi hypothetical protein 0.006 0.0269 0.0864
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0105 0.0395
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0979 0.6477 0.6476
Brugia malayi secreted modular calcium-binding protein 1 0.0041 0.0141 0.0446
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0133 0.032
Schistosoma mansoni cpg binding protein 0.0062 0.0288 0.0283
Brugia malayi hypothetical protein 0.006 0.0269 0.0864
Brugia malayi hypothetical protein 0.013 0.0746 0.242
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0035 0.0102 0.0138
Trichomonas vaginalis rotamase, putative 0.0036 0.0108 0.0248
Trichomonas vaginalis DNA helicase recq1, putative 0.0068 0.0323 0.0766
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0096 0.0516 0.0511
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0055 0.012
Loa Loa (eye worm) hypothetical protein 0.0041 0.0141 0.0446
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0091 0.0086
Echinococcus granulosus Chromo domain 0.0024 0.0031 0.0026
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0031 0.0095
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0143 0.0836 0.2714
Onchocerca volvulus Bile acid receptor homolog 0.0088 0.046 0.1493
Loa Loa (eye worm) malate dehydrogenase 0.0215 0.1318 0.4288
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0055 0.0027
Echinococcus multilocularis caspase 3 0.0078 0.0392 0.0387
Echinococcus multilocularis aldehyde reductase 0.0024 0.0029 0.0024
Loa Loa (eye worm) hypothetical protein 0.0041 0.0147 0.0463
Brugia malayi SET domain containing protein 0.0027 0.0048 0.0142
Trypanosoma cruzi major cysteine proteinase, putative 0.0054 0.0229 0.052
Loa Loa (eye worm) hypothetical protein 0.0131 0.0752 0.2439
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0041 0.0147 0.0142
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0327 0.0758
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0082 0.0189
Schistosoma mansoni RAR-like nuclear receptor 0.0088 0.046 0.0456
Echinococcus multilocularis transcription factor Dp 1 0.0083 0.0427 0.0423
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0034 0.0095 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0186 0.0436
Brugia malayi nuclear hormone receptor family member odr-7 0.0041 0.0147 0.0463
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0024 0.0031 0.0026
Echinococcus multilocularis FTZ F1 alpha 0.0088 0.046 0.0456
Schistosoma mansoni hypothetical protein 0.0044 0.0164 0.0159
Brugia malayi nuclear receptor RXR 0.0041 0.0147 0.0463
Loa Loa (eye worm) hypothetical protein 0.0474 0.3067 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0115 0.0646 0.2459
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0034 0.0095 0.0218
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.0305 0.1069
Plasmodium falciparum glutathione reductase 0.0051 0.0208 0.0654
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0224 0.0219
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0215 0.1318 0.3161
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0303 0.0701
Brugia malayi F/Y-rich N-terminus family protein 0.0024 0.0031 0.0086
Echinococcus multilocularis expressed conserved protein 0.0102 0.0556 0.0552
Brugia malayi PAS domain containing protein 0.0052 0.0218 0.0696
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0098 0.0527 0.1926
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0115 0.0256
Echinococcus granulosus caspase 8 0.0047 0.0186 0.0181
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0062 0.0285 0.0938
Echinococcus granulosus bloom syndrome protein 0.0068 0.0323 0.0318
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0303 0.0701
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0046 0.018 0.0175
Schistosoma mansoni nuclear receptor nhr-48 0.0041 0.0147 0.0142
Plasmodium falciparum kinesin-5 0.0028 0.0059 0.0102
Echinococcus granulosus flap endonuclease 1 0.0028 0.0055 0.005
Brugia malayi hypothetical protein 0.0041 0.0147 0.0463
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0049 0.0101
Loa Loa (eye worm) inositol-1 0.004 0.0133 0.042
Schistosoma mansoni lozenge 0.0059 0.0268 0.0263
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0088 0.046 0.1487
Loa Loa (eye worm) oxidoreductase 0.0034 0.0095 0.0296
Echinococcus granulosus zinc finger protein 0.0054 0.023 0.0225
Trichomonas vaginalis aldo-keto reductase, putative 0.0034 0.0095 0.0218
Plasmodium vivax pyruvate kinase, putative 0.0037 0.0115 0.0421
Trypanosoma cruzi mitochondrial malate dehydrogenase, putative 0.0208 0.1269 0.2942
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0635 0.4158 1
Wolbachia endosymbiont of Brugia malayi 3-methyladenine DNA glycosylase 0.0236 0.146 0.5099
Trichomonas vaginalis alpha-glucosidase, putative 0.0079 0.0397 0.0945
Loa Loa (eye worm) oxidoreductase 0.0034 0.0095 0.0296
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0092 0.049 0.1128
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0088 0.046 0.1487
Brugia malayi Bloom's syndrome protein homolog 0.0068 0.0323 0.1039
Echinococcus granulosus chromobox protein 1 0.0087 0.0452 0.0448
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0084 0.0431 0.1026
Loa Loa (eye worm) hypothetical protein 0.0057 0.0252 0.0809
Brugia malayi nuclear receptor NHR-88 0.0041 0.0147 0.0463
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0088 0.046 0.0456
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0125 0.0288
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0191 0.0448
Loa Loa (eye worm) hypothetical protein 0.0083 0.043 0.1388
Trypanosoma brucei prostaglandin f synthase 0.0034 0.0095 0.0219
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0327 0.0758
Schistosoma mansoni inositol monophosphatase 0.004 0.0133 0.0128
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0032 0.0083 0.0078
Toxoplasma gondii histone lysine methyltransferase SET1 0.0132 0.076 0.2764
Schistosoma mansoni phd/f-box containing protein 0.0034 0.0097 0.0092
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0055 0.0115
Echinococcus multilocularis thyroid hormone receptor alpha 0.0223 0.137 0.1366
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0034 0.0097 0.0213
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0058 0.0129
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0057 0.0053
Trypanosoma brucei metacaspase 0.0047 0.0186 0.043
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0088 0.046 0.0456
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.0305 0.0615
Leishmania major glycosomal malate dehydrogenase 0.0208 0.1269 0.2879
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0065 0.0303 0.0717
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0105 0.0253
Trichomonas vaginalis malate dehydrogenase, putative 0.0215 0.1318 0.3161
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0303 0.0701
Entamoeba histolytica aldose reductase, putative 0.0034 0.0095 0.0229
Trichomonas vaginalis aldo/keto reductase, putative 0.0034 0.0095 0.0218
Trichomonas vaginalis aldo-keto reductase, putative 0.0034 0.0095 0.0218
Onchocerca volvulus Putative organic anion transporter 0.006 0.0269 0.0869
Trichomonas vaginalis sucrase-isomaltase, putative 0.0079 0.0397 0.0945
Trypanosoma brucei DNA polymerase IV, putative 0.0065 0.0303 0.0701
Entamoeba histolytica malate dehydrogenase, putative 0.0215 0.1318 0.3169
Echinococcus granulosus ATP dependent DNA helicase Q1 0.004 0.0139 0.0134
Loa Loa (eye worm) hypothetical protein 0.0041 0.0141 0.0446
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0305 0.03
Echinococcus granulosus transitional endoplasmic reticulum atpase 0.0031 0.0077 0.0072
Plasmodium vivax hypothetical protein, conserved 0.0047 0.0186 0.068
Giardia lamblia DINP protein human, muc B family 0.0043 0.0158 0.0252
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0125 0.0288
Trichomonas vaginalis DNA helicase recq, putative 0.0046 0.0177 0.0414
Echinococcus multilocularis Chromobox protein 3 0.0024 0.0031 0.0026
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0115 0.0646 0.2459
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0127 0.0293
Entamoeba histolytica transitional endoplasmic reticulum ATPase, putative 0.003 0.0066 0.016
Echinococcus multilocularis neuropeptide s receptor 0.1012 0.6707 0.6705
Echinococcus granulosus histone lysine methyltransferase setb 0.007 0.0342 0.0337
Trypanosoma cruzi DNA polymerase kappa, putative 0.0065 0.0303 0.0692
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0079 0.0397 0.1435
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0088 0.046 0.1493
Brugia malayi nuclear receptor RXR 0.0046 0.018 0.0572
Trichomonas vaginalis aldo-keto reductase, putative 0.0034 0.0095 0.0218
Leishmania major malate dehydrogenase 0.0208 0.1269 0.2879
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.031 0.1963 1
Giardia lamblia Aldose reductase 0.0034 0.0095 0.0099
Echinococcus multilocularis survival motor neuron protein 1 0.0261 0.163 0.1626
Mycobacterium tuberculosis Probable dehydrogenase 0.0115 0.0646 0.2459
Onchocerca volvulus 0.0053 0.0226 0.0729
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.0305 0.03
Schistosoma mansoni thyroid hormone receptor 0.0223 0.137 0.1366
Trichomonas vaginalis rotamase, putative 0.0035 0.0102 0.0234
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0219 0.0699
Brugia malayi photoreceptor-specific nuclear receptor 0.0088 0.046 0.1487
Brugia malayi jmjC domain containing protein 0.0034 0.0097 0.03
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0186 0.0436
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0024 0.0031 0.0095
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0034 0.0097 0.0335
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0034 0.0095 0.0091
Brugia malayi jmjC domain containing protein 0.0128 0.073 0.2368
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0034 0.0095 0.0295
Loa Loa (eye worm) hypothetical protein 0.0046 0.018 0.0573
Plasmodium falciparum lactate dehydrogenase, putative 0.0188 0.114 0.4099
Echinococcus granulosus caspase 2 0.0091 0.0484 0.0479
Mycobacterium leprae PROBABLE DNA POLYMERASE III (ALPHA CHAIN) DNAE1 (DNA NUCLEOTIDYLTRANSFERASE) 0.0229 0.1412 0.7149
Schistosoma mansoni pyruvate kinase 0.0037 0.0115 0.011
Onchocerca volvulus 0.0121 0.0681 0.2212
Trypanosoma brucei glucosidase, putative 0.0079 0.0397 0.0921
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0041 0.0088
Trypanosoma cruzi metacaspase, putative 0.0047 0.0186 0.0421
Loa Loa (eye worm) hypothetical protein 0.0034 0.0097 0.03
Schistosoma mansoni hypothetical protein 0.0045 0.017 0.0165
Loa Loa (eye worm) hypothetical protein 0.0029 0.0064 0.0194
Loa Loa (eye worm) hypoxia-induced factor 1 0.0161 0.0954 0.3101
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0064 0.0143
Echinococcus multilocularis ecdysone induced protein 78C 0.0088 0.046 0.0456
Loa Loa (eye worm) hypothetical protein 0.0026 0.0043 0.0125
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0127 0.0293
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.032 0.203 0.2026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0635 0.4158 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0147 0.0142
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0088 0.046 0.0456
Trypanosoma brucei 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0107 0.0588 0.1365
Brugia malayi Nuclear hormone receptor E75 0.0041 0.0147 0.0463
Loa Loa (eye worm) acetyltransferase 0.032 0.203 0.6612
Loa Loa (eye worm) hypothetical protein 0.0088 0.046 0.1487
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0043 0.0125
Trichomonas vaginalis chromobox protein, putative 0.0087 0.0452 0.1077
Onchocerca volvulus 0.0255 0.1588 0.5174
Toxoplasma gondii lactate dehydrogenase LDH1 0.0425 0.2736 1
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0098 0.0527 0.1257
Schistosoma mansoni follistatin 0.0041 0.0141 0.0137
Mycobacterium ulcerans oxidoreductase 0.0034 0.0095 0.0212
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0096 0.0516 0.0511
Loa Loa (eye worm) transcription factor SMAD2 0.0128 0.0729 0.2365
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0186 0.0662
Onchocerca volvulus 0.006 0.0269 0.0869
Chlamydia trachomatis DNA polymerase III subunit alpha 0.0228 0.1404 1
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0133 0.0309
Echinococcus granulosus lamin 0.0059 0.0262 0.0258
Onchocerca volvulus 0.0034 0.0095 0.0301
Schistosoma mansoni hypothetical protein 0.0889 0.5873 0.5871
Trichomonas vaginalis aldo-keto reductase, putative 0.0034 0.0095 0.0218
Schistosoma mansoni DNA helicase recq1 0.004 0.0139 0.0134
Schistosoma mansoni alpha-glucosidase 0.0305 0.1926 0.1922
Schistosoma mansoni hypothetical protein 0.0298 0.188 0.1876
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0034 0.0095 0.0091
Trichomonas vaginalis alpha-glucosidase, putative 0.0079 0.0397 0.0945
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0047 0.0186 0.0181
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0034 0.0097 0.0222
Brugia malayi ecdysteroid receptor 0.0088 0.046 0.1487
Trichomonas vaginalis malate dehydrogenase, putative 0.0215 0.1318 0.3161
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0041 0.0147 0.0142
Schistosoma mansoni flap endonuclease-1 0.0025 0.0036 0.0032
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0029 0.0064 0.0143
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0024 0.0031 0.0026
Echinococcus granulosus malate dehydrogenase 0.0208 0.1269 0.1265
Echinococcus granulosus dna polymerase kappa 0.0065 0.0303 0.0298
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0042 0.0089
Plasmodium vivax cell division cycle protein 48 homologue, putative 0.003 0.0066 0.0243
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0031 0.0026
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.007 0.0338 0.0691
Mycobacterium tuberculosis Probable malate dehydrogenase Mdh 0.0215 0.1318 0.5202
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0086
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0088 0.046 0.1487
Plasmodium vivax thioredoxin reductase, putative 0.0051 0.0208 0.076
Brugia malayi hypothetical protein 0.0046 0.018 0.0572
Loa Loa (eye worm) hypothetical protein 0.0041 0.0147 0.0463
Schistosoma mansoni hypothetical protein 0.0135 0.0776 0.0772
Schistosoma mansoni aldo-keto reductase 0.0034 0.0095 0.009
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0979 0.6477 0.6476
Loa Loa (eye worm) hypothetical protein 0.0037 0.0115 0.0361
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0115 0.0366
Schistosoma mansoni hypothetical protein 0.0024 0.0031 0.0026
Trichomonas vaginalis aldo-keto reductase, putative 0.0034 0.0095 0.0218
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0046 0.018 0.0175
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0031 0.0063
Schistosoma mansoni jumonji/arid domain-containing protein 0.0136 0.0782 0.0778
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0041 0.0147 0.0463
Loa Loa (eye worm) ATP-dependent DNA helicase 0.004 0.0139 0.0438
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0041 0.0147 0.0142
Schistosoma mansoni chromobox protein 0.0087 0.0452 0.0448
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0005 0.0000098037
Loa Loa (eye worm) hypothetical protein 0.0046 0.018 0.0573
Echinococcus granulosus chromobox protein 1 0.0087 0.0452 0.0448
Trichomonas vaginalis malate and lactate dehydrogenase, putative 0.0215 0.1318 0.3161
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0034 0.0095 0.0295
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0635 0.4158 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0127 0.0293
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0064 0.0143
Echinococcus granulosus nuclear receptor nhr 48 0.0041 0.0147 0.0142
Toxoplasma gondii hypothetical protein 0.0106 0.0582 0.2111
Echinococcus multilocularis expressed protein 0.0036 0.0108 0.0103
Loa Loa (eye worm) hypothetical protein 0.0121 0.0681 0.2207
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0031 0.0026
Echinococcus granulosus organic anion transporting polypeptide 30B 0.006 0.0269 0.0265
Trichomonas vaginalis Heterochromatin protein, putative 0.0024 0.0031 0.0063
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.004 0.0139 0.0438
Echinococcus granulosus lactate dehydrogenase a 0.0425 0.2736 0.2733
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0115 0.0256
Trypanosoma brucei malate dehydrogenase-related 0.0188 0.114 0.2648
Echinococcus granulosus Chromobox protein 3 0.0024 0.0031 0.0026
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.032 0.203 0.2026
Loa Loa (eye worm) hypothetical protein 0.006 0.0269 0.0864
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0034 0.0097 0.0213
Toxoplasma gondii pyruvate kinase PyK1 0.0037 0.0115 0.0402
Loa Loa (eye worm) hypothetical protein 0.0041 0.0147 0.0463
Brugia malayi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0065 0.0309 0.0992
Echinococcus granulosus follistatin 0.0041 0.0141 0.0137
Loa Loa (eye worm) hypothetical protein 0.0026 0.0043 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0108 0.0248
Echinococcus multilocularis chromobox protein 1 0.0087 0.0452 0.0448
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0186 0.0436
Loa Loa (eye worm) hypothetical protein 0.0028 0.0057 0.0172
Onchocerca volvulus 0.0088 0.046 0.1493
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0327 0.0758
Echinococcus granulosus lysine specific demethylase 5A 0.0136 0.0782 0.0778
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0327 0.0758
Schistosoma mansoni nuclear hormone receptor 0.0088 0.046 0.0456
Schistosoma mansoni malate dehydrogenase 0.0425 0.2736 0.2733
Onchocerca volvulus 0.0474 0.3067 1
Plasmodium vivax DNA-3-methyladenine glycosylase, putative 0.0236 0.146 0.5337
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0041 0.0141 0.0499
Brugia malayi Pre-SET motif family protein 0.0224 0.1379 0.4489
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0034 0.0095 0.0218
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0088 0.046 0.0456
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0088 0.046 0.1487
Leishmania major glycosyl hydrolase-like protein 0.0029 0.0064 0.0049
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0046 0.0177 0.0409
Echinococcus granulosus expressed conserved protein 0.0102 0.0556 0.0552
Schistosoma mansoni chromobox protein 0.0087 0.0452 0.0448
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0126 0.0122
Echinococcus multilocularis aldo keto reductase 0.0034 0.0095 0.0091
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0041 0.0141 0.0446
Schistosoma mansoni lamin 0.0059 0.0262 0.0258
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0125 0.0192
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0143 0.0836 0.1933
Entamoeba histolytica 2,3-bisphosphoglycerate-independentphosphoglycerate mutase, putative 0.0059 0.0264 0.0635
Leishmania major DNA polymerase eta, putative 0.0036 0.011 0.0158
Loa Loa (eye worm) hypothetical protein 0.0041 0.0147 0.0463
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0134 0.0769 0.0764
Trypanosoma cruzi DNA polymerase kappa, putative 0.0065 0.0303 0.0692
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0127 0.0293
Schistosoma mansoni organic anion transporter 0.006 0.0269 0.0265
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0191 0.0186
Onchocerca volvulus 0.0034 0.0095 0.0301
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0096 0.0516 0.0511
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0088 0.046 0.0456
Echinococcus granulosus FTZ F1 alpha 0.0088 0.046 0.0456
Entamoeba histolytica hypothetical protein 0.0021 0.0005 0.0012
Echinococcus granulosus survival motor neuron protein 1 0.0261 0.163 0.1626
Schistosoma mansoni hypothetical protein 0.0033 0.0091 0.0086
Loa Loa (eye worm) hypothetical protein 0.006 0.0269 0.0864
Brugia malayi hypothetical protein 0.0046 0.018 0.0572
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0656 0.4301 1
Echinococcus granulosus lactate dehydrogenase a 0.0425 0.2736 0.2733
Mycobacterium tuberculosis Possible 3-methyladenine DNA glycosylase Mpg 0.0236 0.146 0.5784
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0635 0.4158 1
Schistosoma mansoni cell division control protein 48 aaa family protein 0.003 0.0066 0.0062
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0112 0.0626 0.1446
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0092 0.049 0.1128
Trypanosoma cruzi metacaspase, putative 0.0047 0.0186 0.0421
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0084 0.0431 0.0426
Loa Loa (eye worm) steroid hormone receptor 0.0088 0.046 0.1487
Loa Loa (eye worm) malate dehydrogenase 0.0208 0.1269 0.4129
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0135 0.0776 0.0772
Loa Loa (eye worm) hypothetical protein 0.0041 0.0147 0.0463
Giardia lamblia GTOR 0.0048 0.0191 0.0333
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0191 0.0608
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0084 0.0431 0.0426
Brugia malayi acetyltransferase, GNAT family protein 0.032 0.203 0.6612
Entamoeba histolytica malate dehydrogenase, putative 0.0425 0.2736 0.658
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0088 0.046 0.0456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0041 0.0088
Giardia lamblia 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0107 0.0588 0.13
Loa Loa (eye worm) hypothetical protein 0.0026 0.004 0.0115
Loa Loa (eye worm) hypothetical protein 0.0041 0.0141 0.0446
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0058 0.0256 0.0251
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0186 0.0436
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0115 0.0646 0.3189
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.011 0.0245
Trypanosoma brucei Valosin-containing protein 0.003 0.0066 0.0151
Loa Loa (eye worm) hypothetical protein 0.0109 0.0601 0.1946
Schistosoma mansoni jumonji/arid domain-containing protein 0.0136 0.0782 0.0778
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0191 0.0608
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0133 0.0309
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0086
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0036 0.011 0.0106
Trichomonas vaginalis malate dehydrogenase, putative 0.0215 0.1318 0.3161
Schistosoma mansoni terminal deoxycytidyl transferase 0.0036 0.011 0.0106
Trichomonas vaginalis alpha-glucosidase, putative 0.0079 0.0397 0.0945
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0005 0.0000098037
Echinococcus granulosus lactate dehydrogenase protein 0.0425 0.2736 0.2733
Schistosoma mansoni aldo-keto reductase 0.0034 0.0095 0.009
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0075 0.017
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0133 0.0129
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0042 0.0149 0.0144
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0108 0.0248
Leishmania major 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0107 0.0588 0.128
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0034 0.0095 0.0091
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0311 0.1965 0.4562
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0133 0.0469
Plasmodium vivax glutathione reductase, putative 0.0051 0.0208 0.076
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0186 0.0436
Brugia malayi chromobox protein homolog 3 0.0054 0.0231 0.0738
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0088 0.046 0.1487
Brugia malayi prostaglandin transporter 0.006 0.0269 0.0864
Echinococcus granulosus thyroid hormone receptor alpha 0.0041 0.0147 0.0142
Brugia malayi jmjC domain containing protein 0.0034 0.0097 0.03
Toxoplasma gondii malate dehydrogenase MDH 0.0425 0.2736 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0041 0.0147 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0088 0.046 0.1487
Loa Loa (eye worm) oxidoreductase 0.0034 0.0095 0.0296
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0115 0.0646 0.2459
Echinococcus granulosus ecdysone induced protein 78C 0.0088 0.046 0.0456
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0029 0.0064 0.02
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0133 0.0298
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0253 0.0811
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0031 0.0063
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0143 0.0836 0.0831
Schistosoma mansoni rotamase 0.0036 0.0108 0.0103
Plasmodium falciparum DNA-3-methyladenine glycosylase, putative 0.0236 0.146 0.5284
Loa Loa (eye worm) hypothetical protein 0.0054 0.0231 0.0739
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0143 0.0836 0.2713
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.004 0.0139 0.0438
Echinococcus multilocularis musashi 0.0059 0.0262 0.0258
Echinococcus multilocularis dna polymerase eta 0.0036 0.011 0.0106
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0635 0.4158 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0034 0.0095 0.0091
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0074 0.0069
Brugia malayi M-phase phosphoprotein, mpp8 0.0121 0.0681 0.2207
Entamoeba histolytica hypothetical protein 0.0038 0.0126 0.0304
Toxoplasma gondii cell division protein CDC48CY 0.0031 0.0077 0.0263
Loa Loa (eye worm) hypothetical protein 0.0027 0.0049 0.0143
Entamoeba histolytica recQ family helicase, putative 0.0046 0.0177 0.0426
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0147 0.0142
Loa Loa (eye worm) independent phosphoglycerate mutase isoform 2 0.0107 0.0588 0.1905
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0115 0.0266
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0049 0.0064
Trichomonas vaginalis maltase-glucoamylase, putative 0.0079 0.0397 0.0945
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.004 0.0139 0.0134
Loa Loa (eye worm) kinesin-like protein KLP2 0.0028 0.0059 0.0176
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0303 0.0701
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0058 0.0129
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0084 0.0431 0.0426
Brugia malayi Cell death protein 3 precursor 0.0091 0.0484 0.1564
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0186 0.0436
Loa Loa (eye worm) hypothetical protein 0.0034 0.0097 0.03
Schistosoma mansoni agrin 0.0041 0.0141 0.0137
Echinococcus multilocularis caspase 8 0.0047 0.0186 0.0181
Echinococcus granulosus phd:f box containing protein 0.0034 0.0097 0.0092
Trypanosoma cruzi cytosolic malate dehydrogenase, putative 0.0215 0.1318 0.3055
Schistosoma mansoni coup transcription factor 0.0088 0.046 0.0456
Brugia malayi Glycosyl hydrolases family 31 protein 0.0079 0.0397 0.1281
Loa Loa (eye worm) hypothetical protein 0.0085 0.0441 0.1424
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0115 0.0266
Echinococcus granulosus Protein patched homolog 1 0.0047 0.0182 0.0177
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0147 0.0142
Schistosoma mansoni alpha glucosidase 0.0079 0.0397 0.0393
Trichomonas vaginalis malate dehydrogenase, putative 0.0215 0.1318 0.3161
Schistosoma mansoni kinesin eg-5 0.0028 0.0059 0.0054
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0053 0.0221 0.0217
Schistosoma mansoni hypothetical protein 0.0045 0.0169 0.0165
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0088 0.046 0.0456
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0224 0.1379 0.4489
Brugia malayi polk-prov protein 0.004 0.0134 0.0423
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0097 0.03
Brugia malayi hypothetical protein 0.0038 0.0126 0.0397
Brugia malayi hypothetical protein 0.0269 0.1683 0.548
Onchocerca volvulus 0.0034 0.0095 0.0301
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0125 0.0288
Loa Loa (eye worm) hypothetical protein 0.0047 0.0182 0.0577
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0088 0.046 0.1487
Entamoeba histolytica kinesin, putative 0.0028 0.0059 0.0141
Plasmodium vivax multidomain scavenger receptor, putative 0.0085 0.0441 0.1611
Brugia malayi hypothetical protein 0.0085 0.0441 0.1424
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0051 0.0208 0.0673
Schistosoma mansoni rab6-interacting 0.0085 0.0441 0.0436
Echinococcus multilocularis jumonji domain containing 1A 0.0034 0.0097 0.0092
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0115 0.0366
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0128 0.0733 0.2814
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0143 0.0836 0.0831
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0115 0.0366
Mycobacterium leprae Probable pyruvate kinase PykA 0.0037 0.0115 0.0446
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE2 (DNA nucleotidyltransferase) 0.0229 0.1412 0.5585
Loa Loa (eye worm) hypothetical protein 0.0085 0.0441 0.1424
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0088 0.046 0.0456
Echinococcus granulosus intermediate filament protein 0.0059 0.0262 0.0258
Schistosoma mansoni lamin 0.0059 0.0262 0.0258
Plasmodium falciparum flap endonuclease 1 0.0028 0.0055 0.0086
Echinococcus multilocularis aldo keto reductase 0.0034 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0175 0.1046 0.3399
Echinococcus multilocularis cytosolic malate dehydrogenase 0.0215 0.1318 0.1314
Brugia malayi Nuclear hormone receptor-like 1 0.0046 0.018 0.0572
Loa Loa (eye worm) hypothetical protein 0.0044 0.0164 0.052
Echinococcus multilocularis cytosolic malate dehydrogenase 0.0215 0.1318 0.1314
Echinococcus granulosus cpg binding protein 0.007 0.034 0.0336
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0031 0.0063
Loa Loa (eye worm) hypothetical protein 0.0474 0.3067 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0126 0.0122
Echinococcus granulosus lipoxygenase domain containing protein 0.0085 0.0441 0.0436
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0398 0.0394
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0088 0.046 0.0456
Echinococcus multilocularis caspase 0.0125 0.0711 0.0707
Plasmodium vivax lactate/malate dehydrogenase, putative 0.0188 0.114 0.4166
Giardia lamblia Pyruvate kinase 0.0037 0.0115 0.0148
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0005 0.0000098037
Echinococcus granulosus caspase 3 0.0078 0.0392 0.0387
Mycobacterium ulcerans malate dehydrogenase 0.0215 0.1318 0.5202
Echinococcus granulosus expressed protein 0.0036 0.0108 0.0103
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0084 0.0431 0.0426
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0296
Leishmania major hypothetical protein, conserved 0.0033 0.0091 0.0112
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0092 0.049 0.1128
Brugia malayi Intermediate filament tail domain containing protein 0.0059 0.0262 0.0841
Leishmania major DNA polymerase kappa, putative 0.0043 0.0158 0.027
Trypanosoma brucei DNA polymerase IV, putative 0.0065 0.0303 0.0701
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0055 0.018
Echinococcus multilocularis lactate dehydrogenase a 0.0425 0.2736 0.2733
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0034 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.006 0.0269 0.0864
Trichomonas vaginalis aldo-keto reductase, putative 0.0034 0.0095 0.0218
Schistosoma mansoni chromobox protein 0.0024 0.0031 0.0026
Loa Loa (eye worm) hypothetical protein 0.004 0.0134 0.0423
Loa Loa (eye worm) hypothetical protein 0.0096 0.0517 0.1672
Echinococcus multilocularis follistatin 0.0041 0.0141 0.0137
Loa Loa (eye worm) MH2 domain-containing protein 0.0128 0.0729 0.2365
Schistosoma mansoni caspase-7 (C14 family) 0.0091 0.0484 0.0479
Echinococcus multilocularis cpg binding protein 0.007 0.034 0.0336
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0086
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0034 0.0095 0.0091
Entamoeba histolytica acetyltransferase, GNAT family 0.0085 0.044 0.1058
Loa Loa (eye worm) hypothetical protein 0.0047 0.0186 0.0592
Brugia malayi lactate dehydrogenase. 0.0425 0.2736 0.892
Schistosoma mansoni thyroid hormone receptor 0.0223 0.137 0.1366
Echinococcus multilocularis L lactate dehydrogenase B chain 0.0425 0.2736 0.2733
Echinococcus granulosus Polycystic kidney disease protein 0.0085 0.0441 0.0436
Loa Loa (eye worm) glutathione reductase 0.0051 0.0208 0.0664
Trypanosoma cruzi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0107 0.0588 0.1357
Schistosoma mansoni blooms syndrome DNA helicase 0.0047 0.0184 0.0179
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0031 0.0063
Echinococcus multilocularis transitional endoplasmic reticulum atpase 0.0031 0.0077 0.0072
Trypanosoma brucei metacaspase MCA2 0.0047 0.0186 0.043
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0431 0.0999
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0088 0.046 0.0456
Giardia lamblia Fructose-bisphosphate aldolase 0.0635 0.4158 1
Echinococcus granulosus ATP dependent DNA helicase Q5 0.004 0.0139 0.0134
Echinococcus multilocularis lamin 0.0059 0.0262 0.0258
Mycobacterium tuberculosis Conserved hypothetical protein 0.0036 0.011 0.0274
Leishmania major malate dehydrogenase, putative 0.0188 0.114 0.2575
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0031 0.0026
Echinococcus multilocularis malate dehydrogenase 0.0208 0.1269 0.1265
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0005 0.0000098037
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0191 0.0432
Loa Loa (eye worm) oxidoreductase 0.0034 0.0095 0.0296
Brugia malayi Doublecortin family protein 0.0085 0.0441 0.1424
Schistosoma mansoni patched 1 0.0047 0.0182 0.0177
Trichomonas vaginalis aldo-keto reductase, putative 0.0034 0.0095 0.0218
Brugia malayi hypothetical protein 0.0041 0.0147 0.0463
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0191 0.0186
Trypanosoma cruzi malate dehydrogenase, putative 0.0188 0.114 0.2641
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0397 0.0912
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0635 0.4158 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0091 0.0315
Trypanosoma cruzi metacaspase, putative 0.0047 0.0186 0.0421
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0231 0.0544
Schistosoma mansoni caspase-3 (C14 family) 0.0125 0.0711 0.0707
Plasmodium vivax SET domain protein, putative 0.0033 0.0091 0.0334
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0034 0.0095 0.0218
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0327 0.0758
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.007 0.0338 0.0333
Leishmania major pyruvate kinase 0.0037 0.0115 0.0169
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0133 0.0368
Brugia malayi nuclear receptor NHR-67 0.0041 0.0147 0.0463
Echinococcus multilocularis lipoxygenase domain containing protein 0.0085 0.0441 0.0436
Trichomonas vaginalis aldo/keto reductase, putative 0.0034 0.0095 0.0218
Loa Loa (eye worm) hypothetical protein 0.0046 0.018 0.0573
Echinococcus multilocularis pyruvate kinase 0.0037 0.0115 0.011
Trypanosoma cruzi MFS transporter, putative 0.006 0.0269 0.0615
Loa Loa (eye worm) hypothetical protein 0.0041 0.0147 0.0463
Echinococcus granulosus JmjC domain containing protein 4 0.0034 0.0097 0.0092
Brugia malayi ImpB/MucB/SamB family protein 0.0036 0.011 0.0345
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0034 0.0095 0.0091
Trichomonas vaginalis malate dehydrogenase, putative 0.0092 0.0487 0.116
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0109 0.0601 0.1445
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0288 0.0925
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0191 0.0347
Loa Loa (eye worm) hypothetical protein 0.0041 0.0147 0.0463
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0127 0.0293
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0098 0.0527 0.1911
Echinococcus granulosus single minded 2 0.0039 0.0127 0.0122
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0097 0.03
Schistosoma mansoni nuclear receptor 0.0041 0.0147 0.0142
Onchocerca volvulus 0.0041 0.0147 0.0469
Brugia malayi hypoxia-induced factor 1 0.0161 0.0954 0.3101
Brugia malayi glutathione reductase 0.0051 0.0208 0.0663
Brugia malayi Kinesin motor domain containing protein 0.0028 0.0059 0.0176
Echinococcus granulosus aldo keto reductase 0.0034 0.0095 0.0091
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0088 0.046 0.1487
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0303 0.0701
Trichomonas vaginalis alpha-glucosidase, putative 0.0029 0.0064 0.0143
Trichomonas vaginalis chromobox protein, putative 0.0057 0.0252 0.0596
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0143 0.0836 0.1861
Trichomonas vaginalis chromobox protein, putative 0.0057 0.0252 0.0596
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0191 0.0432
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0046 0.0177 0.0314
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0303 0.0701
Loa Loa (eye worm) hypothetical protein 0.0261 0.163 0.5308
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0034 0.0095 0.0091
Loa Loa (eye worm) sodium-independent organic anion transporter 0.006 0.0269 0.0864
Onchocerca volvulus 0.0059 0.0262 0.0847
Brugia malayi jmjC domain containing protein 0.0136 0.0782 0.2538
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0127 0.0293
Onchocerca volvulus 0.0053 0.0224 0.0721
Brugia malayi hypothetical protein 0.0175 0.1046 0.3399
Schistosoma mansoni hypothetical protein 0.0085 0.0441 0.0436
Echinococcus multilocularis kinesin family 1 0.0219 0.1347 0.1343
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0062 0.0287 0.0657
Trypanosoma brucei pyruvate kinase 1, putative 0.0037 0.0115 0.0265
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0031 0.0095
Schistosoma mansoni methyl-cpg binding protein mbd 0.0037 0.0117 0.0112
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.0082 0.0187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.006 0.0134
Entamoeba histolytica hypothetical protein 0.0024 0.0031 0.0075
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0088 0.046 0.0456
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0043 0.0074
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0078 0.0394 0.0389
Echinococcus multilocularis transfer RNA-Lys 0.0039 0.0127 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0186 0.0436
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0029 0.0064 0.0143
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0143 0.0836 0.1933
Loa Loa (eye worm) hypothetical protein 0.0298 0.188 0.6125
Trichomonas vaginalis maltase-glucoamylase, putative 0.0029 0.0064 0.0143
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0088 0.046 0.0456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0144 0.0334
Trichomonas vaginalis malate dehydrogenase, putative 0.0215 0.1318 0.3161
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0327 0.075
Echinococcus multilocularis JmjC domain containing protein 4 0.0034 0.0097 0.0092
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0043 0.0158 0.0469
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0031 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0303 0.0701
Echinococcus granulosus apoptotic protease activating factor 1 0.0044 0.0164 0.0159
Trichomonas vaginalis 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0107 0.0588 0.1404
Echinococcus granulosus fetal alzheimer antigen falz 0.0053 0.0221 0.0217
Echinococcus granulosus dna polymerase eta 0.0036 0.011 0.0106
Wolbachia endosymbiont of Brugia malayi malate dehydrogenase 0.0425 0.2736 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0109 0.0601 0.0596
Echinococcus multilocularis phd:f box containing protein 0.0034 0.0097 0.0092
Brugia malayi Associated with TFs and helicases family protein 0.0024 0.0031 0.0086
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0298 0.188 0.1876
Loa Loa (eye worm) hypothetical protein 0.004 0.0139 0.0438
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0298 0.188 0.1876
Loa Loa (eye worm) hypothetical protein 0.006 0.0269 0.0864
Trypanosoma brucei aldo-keto reductase, putative 0.0034 0.0095 0.0219
Schistosoma mansoni organic anion transporter 0.006 0.0269 0.0265
Echinococcus multilocularis bloom syndrome protein 0.0068 0.0323 0.0318
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.007 0.0342 0.0337
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0047 0.0186 0.0592
Brugia malayi CHE-14 protein 0.0047 0.0182 0.0577
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0186 0.0436
Leishmania major aldo-keto reductase-like protein 0.0034 0.0095 0.0122
Leishmania major cytosolic malate dehydrogenase 0.0215 0.1318 0.2993
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.0305 0.03
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0031 0.0114
Echinococcus granulosus transcription factor Dp 1 0.0083 0.0427 0.0423
Schistosoma mansoni malate dehydrogenase 0.0215 0.1318 0.1313
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0053 0.0221 0.0217
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.004 0.0139 0.0134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0042 0.0089
Plasmodium vivax heterochromatin protein 1, putative 0.0024 0.0031 0.0114
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0046 0.0177 0.04
Echinococcus granulosus hypothetical protein 0.0034 0.0095 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0031 0.0063
Mycobacterium ulcerans 3-methyladenine DNA glycosylase 0.0236 0.146 0.5784
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0186 0.0662
Echinococcus granulosus expressed protein 0.0399 0.2564 0.256
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0034 0.0095 0.0091
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0305 0.1069
Echinococcus multilocularis zinc finger protein 0.0054 0.023 0.0225
Trichomonas vaginalis bromodomain-containing protein, putative 0.0098 0.0527 0.1257
Trypanosoma cruzi malate dehydrogenase, putative 0.0208 0.1269 0.2942
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0036 0.0108 0.0336
Loa Loa (eye worm) hypothetical protein 0.0088 0.046 0.1487
Leishmania major metacaspase, putative 0.0047 0.0186 0.0335
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0084 0.0431 0.0911
Schistosoma mansoni apoptosis regulator bax 0.0298 0.188 0.1876
Schistosoma mansoni bromodomain containing protein 0.0149 0.0872 0.0867
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0042 0.0089
Schistosoma mansoni L-lactate dehydrogenase 0.0188 0.114 0.1135
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0134 0.0309
Plasmodium vivax metacaspase 1, putative 0.0047 0.0186 0.068
Trypanosoma cruzi metacaspase 5, putative 0.0047 0.0186 0.0421
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0034 0.0095 0.0091
Schistosoma mansoni hypothetical protein 0.0053 0.0226 0.0221
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0043 0.0104
Giardia lamblia Aldose reductase 0.0034 0.0095 0.0099
Echinococcus multilocularis lysosomal alpha glucosidase 0.0354 0.2259 0.2255

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) 0 nM Compound was evaluated for calcium mobilization in Jurkat cells; Not determined ChEMBL. 10866391
EC50 (functional) = 480 nM Compound was evaluated for the inhibition of amylase secretion in isolated rat pancreatic acini ChEMBL. 10866391
IC50 (binding) = 150 nM Compound was evaluated for the binding affinity towards rat pancreatic Cholecystokinin type A receptor ChEMBL. 10866391
IC50 (binding) = 150 nM Compound was evaluated for the binding affinity towards rat pancreatic Cholecystokinin type A receptor ChEMBL. 10866391
IC50 (binding) = 3600 nM Binding affinity towards Cholecystokinin type B receptor in mouse cortex membrane ChEMBL. 10866391
IC50 (binding) = 3600 nM Binding affinity towards Cholecystokinin type B receptor in mouse cortex membrane ChEMBL. 10866391
IC50 (binding) = 0.075 uM Inhibition of [125I]- Bolton-Hunter CCK-26-33 binding to Cholecystokinin type A receptor of rat pancreas ChEMBL. No reference
IC50 (binding) = 0.075 uM Inhibition of [125I]- Bolton-Hunter CCK-26-33 binding to Cholecystokinin type A receptor of rat pancreas ChEMBL. No reference
IC50 (binding) = 18 uM Inhibition of [125I]- Bolton-Hunter CCK-26-33 binding to Cholecystokinin type B receptor of mouse cerebral cortex ChEMBL. No reference
IC50 (binding) = 18 uM Inhibition of [125I]- Bolton-Hunter CCK-26-33 binding to Cholecystokinin type B receptor of mouse cerebral cortex ChEMBL. No reference
Ratio (binding) = 240 Relative affinity for CCK-B and CCK-A receptors ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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