Detailed information for compound 273903

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 428.442 | Formula: C22H27F3O5
  • H donors: 0 H acceptors: 0 LogP: 5.75 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[C@@H]1[C@@H](Oc2ccc(cc2)C(F)(F)F)O[C@H]2[C@@]34[C@H]1CC[C@@H]([C@H]4CC[C@](O2)(OO3)C)C
  • InChi: 1S/C22H27F3O5/c1-12-4-9-17-13(2)18(26-15-7-5-14(6-8-15)22(23,24)25)27-19-21(17)16(12)10-11-20(3,28-19)29-30-21/h5-8,12-13,16-19H,4,9-11H2,1-3H3/t12-,13-,16+,17+,18-,19-,20-,21-/m1/s1
  • InChiKey: RZVYJPLOSDQGFB-SZMJOESGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0262 0.7387
Schistosoma mansoni formin binding protein and related proteins 0.0021 0.0036 0.0046
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0035 0.0031
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0063 0.0061
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Schistosoma mansoni UDP-glucose 4-epimerase 0.0051 0.0115 0.0154
Echinococcus granulosus voltage gated potassium channel subunit 0.0009 0.0004 0.0002
Trypanosoma brucei aldo-keto reductase, putative 0.0031 0.0063 0.017
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0042 0.005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0025
Leishmania major aldo-keto reductase-like protein 0.0031 0.0063 0.017
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0055 0.0051
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0021 0.005
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0012 0.0013 0.0026
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0063 0.0061
Brugia malayi nuclear hormone receptor 0.0018 0.0029 0.0033
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0023 0.0055
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.006 0.0161
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Echinococcus granulosus tyrosine protein kinase Src42A 0.2303 0.6146 0.6145
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0041 0.1063
Plasmodium falciparum protein kinase, putative 0.1301 0.3464 1
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0197 0.0266
Leishmania major ATP-dependent phosphofructokinase 0.0126 0.0317 0.0906
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Entamoeba histolytica tyrosine kinase, putative 0.1301 0.3464 0.5686
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0012 0.0011 0.0022
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0039 0.0084 0.0112
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0041 0.0107
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0023 0.0055
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.0745 0.1217
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0025
Trichomonas vaginalis NAD dependent epimerase/dehydratase, putative 0.0051 0.0115 0.0322
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0071 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0036 0.0091
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0043 0.0051
Brugia malayi Src substrate cortactin 0.0021 0.0036 0.0041
Schistosoma mansoni 6-phosphofructokinase 0.0126 0.0317 0.0429
Echinococcus granulosus geminin 0.0559 0.1477 0.1476
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus granulosus SH2 motif 0.0981 0.2605 0.2604
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0018 0.0029 0.0033
Trypanosoma brucei Pseudokinase, putative 0.1301 0.3464 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0039 0.0084 0.0112
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1301 0.3464 0.3464
Echinococcus granulosus single minded 2 0.0035 0.0074 0.0073
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Brugia malayi SH2 domain containing protein 0.0981 0.2605 0.3407
Loa Loa (eye worm) phosphofructokinase 0.0126 0.0317 0.0314
Echinococcus multilocularis tyrosine protein kinase 0.1301 0.3464 0.3464
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0018 0.0018
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.0063 0.0077
Entamoeba histolytica serine/threonine kinase, putative 0.1301 0.3464 0.5686
Echinococcus multilocularis glutathione S transferase 0.0032 0.0064 0.0063
Echinococcus multilocularis tyrosine protein kinase HCK 0.1301 0.3464 0.3464
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0013 0.0028
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Onchocerca volvulus 0.2282 0.609 1
Trichomonas vaginalis conserved hypothetical protein 0.1301 0.3464 1
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Schistosoma mansoni tyrosine kinase 0.2282 0.609 0.8258
Entamoeba histolytica receptor protein kinase, putative 0.1301 0.3464 0.5686
Leishmania major elongation factor 1-gamma, putative 0.0016 0.0024 0.0057
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0018 0.0041
Schistosoma mansoni ephrin receptor 0.1301 0.3464 0.4697
Onchocerca volvulus 0.0031 0.0063 0.0097
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0018 0.0029 0.0025
Onchocerca volvulus 0.1301 0.3464 0.5686
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0034 0.0071 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0036 0.0091
Brugia malayi photoreceptor-specific nuclear receptor 0.0039 0.0084 0.0105
Echinococcus multilocularis receptor type guanylyl cyclase 0.1301 0.3464 0.3464
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0063 0.017
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0023 0.0055
Loa Loa (eye worm) TK/EPH protein kinase 0.1301 0.3464 0.3462
Trichomonas vaginalis adenylate cyclase, putative 0.0012 0.0013 0.0026
Loa Loa (eye worm) oxidoreductase 0.0031 0.0063 0.0059
Echinococcus multilocularis tyrosine protein kinase Src64B 0.2303 0.6146 0.6145
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0126 0.0317 0.8967
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0023 0.0055
Leishmania major hypothetical protein, conserved 0.0037 0.0079 0.0217
Entamoeba histolytica serine/threonine kinase, putative 0.1301 0.3464 0.5686
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0021 0.005
Trichomonas vaginalis AGC family protein kinase 0.1301 0.3464 1
Echinococcus multilocularis rho guanine nucleotide exchange factor 7 0.0021 0.0036 0.0034
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0063 0.017
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0139 0.0137
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0039 0.0084 0.0105
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.001
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0035 0.009
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0063 0.0061
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0013 0.0026
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0039 0.0084 0.0105
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0071 0.0194
Entamoeba histolytica hypothetical protein, conserved 0.0021 0.0036 0.0052
Schistosoma mansoni protein kinase 0.1301 0.3464 0.4697
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0021 0.005
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0023 0.0055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0023 0.0055
Loa Loa (eye worm) hypothetical protein 0.012 0.0301 0.0297
Plasmodium falciparum glutathione reductase 0.0016 0.0023 0.0055
Loa Loa (eye worm) hypothetical protein 0.0981 0.2605 0.2603
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0023 0.0025
Leishmania major elongation factor-1 gamma 0.0016 0.0024 0.0057
Entamoeba histolytica SH2-protein kinase domain containing protein 0.2282 0.609 1
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0981 0.2605 0.2604
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0039 0.0084 0.0105
Entamoeba histolytica tyrosine kinase, putative 0.1301 0.3464 0.5686
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.1301 0.3464 0.3462
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0036 0.0091
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0071 0.0194
Loa Loa (eye worm) TK/FER protein kinase 0.1301 0.3464 0.3462
Loa Loa (eye worm) SH2 domain-containing protein 0.0981 0.2605 0.2603
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0029 0.0037
Leishmania major hypothetical protein, conserved 0.1301 0.3464 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0055 0.0054
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0022
Echinococcus multilocularis tyrosine protein kinase shark 0.2282 0.609 0.6089
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.0317 0.0906
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0039 0.0084 0.0083
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.2303 0.6146 0.6145
Trichomonas vaginalis NAD dependent epimerase/dehydratase, putative 0.0051 0.0115 0.0322
Entamoeba histolytica hypothetical protein 0.0021 0.0036 0.0052
Toxoplasma gondii UDP-glucose 4-epimerase 0.0051 0.0115 0.0322
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0025
Loa Loa (eye worm) hypothetical protein 0.0981 0.2605 0.2603
Trichomonas vaginalis STE family protein kinase 0.1301 0.3464 1
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0091 0.0253
Loa Loa (eye worm) TK/FER protein kinase 0.1301 0.3464 0.3462
Echinococcus granulosus tyrosine protein kinase Src64B 0.2303 0.6146 0.6145
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0139 0.0186
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.1301 0.3464 0.3464
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Echinococcus multilocularis Spectrin alpha actinin 0.0021 0.0036 0.0034
Echinococcus granulosus glutathione s transferase mu 0.0032 0.0064 0.0063
Loa Loa (eye worm) TK/KIN6 protein kinase 0.1301 0.3464 0.3462
Echinococcus multilocularis c src tyrosine kinase 0.2303 0.6146 0.6145
Brugia malayi ephrin receptor 1 precursor 0.1301 0.3464 0.4531
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1301 0.3464 0.5686
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0036 0.0091
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0063 0.017
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0039 0.0084 0.0105
Entamoeba histolytica tyrosine kinase, putative 0.1301 0.3464 0.5686
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0023 0.0055
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0042 0.1185
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0041 0.1161
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0032
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0035 0.0033
Brugia malayi tailless protein 0.0018 0.0029 0.0033
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.1301 0.3464 0.3462
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0021 0.002
Echinococcus multilocularis dual specificity testis specific protein kinase 0.1301 0.3464 0.3464
Echinococcus granulosus eukaryotic translation elongation factor 1 0.0016 0.0024 0.0022
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.1301 0.3464 0.5686
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0139 0.3925
Loa Loa (eye worm) TK/FAK protein kinase 0.1301 0.3464 0.3462
Onchocerca volvulus 0.1301 0.3464 0.5686
Trypanosoma cruzi UDP-galactose 4-epimerase, putative 0.0051 0.0115 0.0322
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0013 0.0016
Loa Loa (eye worm) RGC/RGC protein kinase 0.1301 0.3464 0.3462
Brugia malayi SH2 domain containing protein 0.0981 0.2605 0.3407
Brugia malayi hypothetical protein 0.2282 0.609 0.7969
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0022
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0197 0.0253
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0041 0.0107
Echinococcus multilocularis protein KINase family member (kin 25) 0.1301 0.3464 0.3464
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0036 0.0091
Onchocerca volvulus 0.003 0.0061 0.0094
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0981 0.2605 0.2604
Plasmodium falciparum tyrosine kinase-like protein 0.1301 0.3464 1
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Echinococcus multilocularis SHC transforming protein 3 0.0981 0.2605 0.2604
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0043 0.0041
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2282 0.609 0.6089
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1301 0.3464 0.5686
Giardia lamblia DINP protein human, muc B family 0.0021 0.0035 0.0085
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0013 0.0028
Echinococcus multilocularis integrin linked protein kinase 0.1301 0.3464 0.3464
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0025
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0745 0.2141
Brugia malayi hypothetical protein 0.0021 0.0035 0.0041
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0025
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0197 0.0196
Loa Loa (eye worm) hypothetical protein 0.0981 0.2605 0.2603
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0035 0.0045
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0035 0.0045
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0039 0.0084 0.008
Entamoeba histolytica hypothetical protein 0.0035 0.0074 0.0115
Schistosoma mansoni tyrosine-protein kinase fps85d 0.1301 0.3464 0.4697
Entamoeba histolytica unconventional myosin IB 0.0021 0.0036 0.0052
Loa Loa (eye worm) TK/FER protein kinase 0.2282 0.609 0.6089
Echinococcus multilocularis retinal guanylyl cyclase 2 0.1301 0.3464 0.3464
Echinococcus granulosus tyrosine protein kinase csk 0.1301 0.3464 0.3464
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0035 0.0993
Brugia malayi nuclear receptor NHR-88 0.0018 0.0029 0.0033
Brugia malayi hypothetical protein 0.0018 0.0029 0.0033
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0039 0.0084 0.0083
Brugia malayi nuclear receptor RXR 0.0018 0.0029 0.0033
Entamoeba histolytica hypothetical protein 0.1301 0.3464 0.5686
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0063 0.0061
Brugia malayi orphan nuclear receptor NR2E1 0.0018 0.0029 0.0033
Brugia malayi Protein kinase domain containing protein 0.2282 0.609 0.7969
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0026 0.0742
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus multilocularis FL cytokine receptor 0.1301 0.3464 0.3464
Loa Loa (eye worm) TK protein kinase 0.1301 0.3464 0.3462
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0035 0.0033
Schistosoma mansoni tyrosine kinase 0.2303 0.6146 0.8333
Schistosoma mansoni hypothetical protein 0.0021 0.0036 0.0046
Echinococcus granulosus tyrosine kinase 0.2282 0.609 0.6089
Trypanosoma cruzi protein kinase, putative 0.1301 0.3464 1
Loa Loa (eye worm) TK/FER protein kinase 0.2282 0.609 0.6089
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Echinococcus multilocularis nostrin 0.0021 0.0036 0.0034
Plasmodium falciparum protein kinase, putative 0.1301 0.3464 1
Brugia malayi intermediate filament protein 0.0026 0.005 0.0061
Echinococcus granulosus protein kinase 0.1301 0.3464 0.3464
Echinococcus granulosus activated cdc42 kinase 1 0.1301 0.3464 0.3464
Loa Loa (eye worm) SRC-1 0.2303 0.6146 0.6144
Echinococcus multilocularis insulin receptor 0.1301 0.3464 0.3464
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0021 0.0023
Echinococcus multilocularis glutathione S transferase 0.002 0.0033 0.0031
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Echinococcus granulosus tar DNA binding protein 0.0073 0.0177 0.0175
Echinococcus granulosus glutathione S transferase Mu 1 0.0032 0.0064 0.0063
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0041 0.0107
Echinococcus granulosus suppressor of cytokine signaling 6 0.0981 0.2605 0.2604
Schistosoma mansoni aldo-keto reductase 0.0031 0.0063 0.0083
Schistosoma mansoni ephrin receptor 0.1301 0.3464 0.4697
Loa Loa (eye worm) hypothetical protein 0.0981 0.2605 0.2603
Brugia malayi Probable tyrosine-protein kinase kin-31 0.1301 0.3464 0.4531
Onchocerca volvulus 0.0028 0.0055 0.0084
Echinococcus granulosus endophilin A3 0.0021 0.0036 0.0034
Loa Loa (eye worm) oxidoreductase 0.0031 0.0063 0.0059
Entamoeba histolytica hypothetical protein 0.1301 0.3464 0.5686
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0021 0.0036 0.0034
Loa Loa (eye worm) hypothetical protein 0.2282 0.609 0.6089
Brugia malayi SH2 domain containing protein 0.0981 0.2605 0.3407
Loa Loa (eye worm) nuclear hormone receptor 0.0018 0.0029 0.0025
Schistosoma mansoni growth factor receptor-bound protein 0.1001 0.2661 0.3607
Loa Loa (eye worm) nuclear receptor NHR-67 0.0018 0.0029 0.0025
Schistosoma mansoni dreadlocks/dock 0.0021 0.0036 0.0046
Entamoeba histolytica tyrosine kinase, putative 0.1301 0.3464 0.5686
Onchocerca volvulus 0.0981 0.2605 0.4275
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus granulosus kinase suppressor of Ras 1 0.1301 0.3464 0.3464
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0071 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0139 0.3925
Echinococcus granulosus fch and double sh3 domains protein 2 0.0021 0.0036 0.0034
Plasmodium falciparum tyrosine kinase-like protein 0.1301 0.3464 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0981 0.2605 0.3407
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0981 0.2605 0.2604
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0025
Schistosoma mansoni protein kinase 0.1301 0.3464 0.4697
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0063 0.017
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0006 0.0006
Giardia lamblia Protein 21.1 0.1301 0.3464 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0006 0.0005
Brugia malayi SH2 domain containing protein 0.0981 0.2605 0.3407
Schistosoma mansoni tensin 0.0981 0.2605 0.3532
Entamoeba histolytica aldose reductase, putative 0.0031 0.0063 0.0097
Loa Loa (eye worm) TK/FER protein kinase 0.1301 0.3464 0.3462
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0063 0.0061
Loa Loa (eye worm) TK/INSR protein kinase 0.1301 0.3464 0.3462
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Trichomonas vaginalis aldo/keto reductase, putative 0.0031 0.0063 0.017
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0011 0.0022
Toxoplasma gondii phosphofructokinase PFKII 0.0034 0.0071 0.0194
Entamoeba histolytica receptor protein kinase, putative 0.1301 0.3464 0.5686
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2303 0.6146 0.6145
Leishmania major prostaglandin f synthase, putative 0.0031 0.0063 0.017
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0084 0.0083
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Onchocerca volvulus 0.003 0.006 0.0092
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0063 0.017
Loa Loa (eye worm) TK/ALK protein kinase 0.1301 0.3464 0.3462
Entamoeba histolytica hypothetical protein 0.1301 0.3464 0.5686
Echinococcus granulosus slit robo rho gtpase activating protein 1 0.0021 0.0036 0.0034
Echinococcus multilocularis microtubule associated protein 2 0.0675 0.1786 0.1785
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0026 0.0639
Plasmodium vivax glutathione S-transferase, putative 0.0032 0.0064 0.0175
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.1301 0.3464 0.5686
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.006 0.0058
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0031 0.0063 0.017
Echinococcus granulosus tyrosine protein kinase Btk29A 0.1301 0.3464 0.3464
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0177 0.0238
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0041 0.1161
Echinococcus granulosus natriuretic peptide receptor 1 0.1301 0.3464 0.3464
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0031 0.0063 0.1684
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0091 0.0253
Echinococcus multilocularis epidermal growth factor receptor kinase 0.0021 0.0036 0.0034
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0041 0.0107
Schistosoma mansoni cpg binding protein 0.003 0.0059 0.0079
Entamoeba histolytica hypothetical protein 0.1301 0.3464 0.5686
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1301 0.3464 0.3464
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0023 0.0055
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.0317 0.0515
Echinococcus multilocularis glutathione s transferase mu 0.0032 0.0064 0.0063
Trichomonas vaginalis aldo/keto reductase, putative 0.0031 0.0063 0.017
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0063 0.0061
Loa Loa (eye worm) TK/FER protein kinase 0.2282 0.609 0.6089
Echinococcus granulosus hypothetical protein 0.0981 0.2605 0.2604
Trypanosoma brucei elongation factor 1 gamma, putative 0.0016 0.0024 0.0057
Leishmania major protein kinase, putative 0.1301 0.3464 1
Echinococcus granulosus insulin receptor 0.1301 0.3464 0.3464
Echinococcus multilocularis cpg binding protein 0.003 0.0059 0.0058
Schistosoma mansoni pol-related 0.0031 0.0063 0.0083
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0023 0.0055
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0036 0.0091
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0035 0.0034
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0042 0.1185
Echinococcus multilocularis glutathione S transferase 0.0032 0.0064 0.0063
Echinococcus multilocularis tyrosine protein kinase csk 0.1301 0.3464 0.3464
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0063 0.017
Entamoeba histolytica tyrosine kinase, putative 0.1301 0.3464 0.5686
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0063 0.0061
Echinococcus multilocularis glutathione S-transferase 0.0032 0.0064 0.0063
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0063 0.0061
Schistosoma mansoni hydrolase 0.0037 0.0079 0.0105
Brugia malayi hypothetical protein 0.0021 0.0035 0.0041
Echinococcus granulosus 6 phosphofructokinase 0.0126 0.0317 0.0316
Mycobacterium leprae Conserved hypothetical protein 0.0022 0.0039 0.0998
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0035 0.0041
Schistosoma mansoni DNA helicase recq5 0.001 0.0006 0.0006
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.1301 0.3464 0.3464
Entamoeba histolytica hypothetical protein 0.1301 0.3464 0.5686
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0039 0.0084 0.0112
Loa Loa (eye worm) histone methyltransferase 0.001 0.0006 0.0002
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0018 0.0029 0.0041
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.1301 0.3464 0.4697
Plasmodium vivax SET domain protein, putative 0.003 0.006 0.0161
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0023 0.0055
Echinococcus granulosus neuropeptide receptor A26 0.0454 0.1194 0.1193
Loa Loa (eye worm) steroid hormone receptor 0.0039 0.0084 0.008
Leishmania major trypanothione reductase 0.0046 0.0104 0.0288
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0039 0.0084 0.0105
Onchocerca volvulus 0.2282 0.609 1
Echinococcus granulosus SH2 motif 0.0981 0.2605 0.2604
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0009 0.0004 0.0002
Trypanosoma brucei Flagellum attachment zone protein 20 0.1301 0.3464 1
Onchocerca volvulus LIM and SH3 domain protein homolog 0.0021 0.0036 0.0052
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0023 0.0021
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0035 0.009
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0104 0.2852
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0039 0.0084 0.008
Trichomonas vaginalis guanylate cyclase, putative 0.0012 0.0013 0.0026
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0025
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0039 0.0084 0.0112
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.006 0.0079
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.0021 0.0036 0.0032
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0012 0.0013 0.0026
Echinococcus multilocularis raf serine:threonine protein kinase 0.1301 0.3464 0.3464
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0021 0.002
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Schistosoma mansoni zinc finger protein 0.0018 0.0029 0.0037
Toxoplasma gondii protein kinase domain-containing protein 0.1301 0.3464 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.0029 0.0028
Echinococcus multilocularis tyrosine protein kinase csk 0.1301 0.3464 0.3464
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0047
Echinococcus multilocularis hematopoietic lineage cell specific protein 0.0021 0.0036 0.0034
Onchocerca volvulus 0.0039 0.0084 0.0132
Trichomonas vaginalis protein kinase atn1, putative 0.1301 0.3464 1
Trichomonas vaginalis neutrophil cytosolic factor 2, neutrophil NADPH oxidase factor, putative 0.0021 0.0036 0.0091
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0034 0.0071 0.0194
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0981 0.2605 0.2603
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0063 0.0061
Loa Loa (eye worm) TK protein kinase 0.2282 0.609 0.6089
Plasmodium falciparum protein kinase, putative 0.1301 0.3464 1
Onchocerca volvulus 0.0021 0.0036 0.0052
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0023 0.0643
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0035 0.0894
Leishmania major DNA polymerase eta, putative 0.0021 0.0035 0.009
Echinococcus granulosus fibroblast growth factor receptor 4 0.1301 0.3464 0.3464
Loa Loa (eye worm) thyroid receptor interactor 0.0021 0.0036 0.0032
Schistosoma mansoni protein tyrosine kinase 0.1301 0.3464 0.4697
Brugia malayi Sex muscle abnormal protein 5 0.1001 0.2661 0.3479
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0063 0.0061
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0039 0.0084 0.0083
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0023 0.0055
Schistosoma mansoni protein kinase 0.1301 0.3464 0.4697
Trichomonas vaginalis serine-threonine protein kinase, putative 0.1301 0.3464 1
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1301 0.3464 0.3464
Entamoeba histolytica tyrosine kinase, putative 0.1301 0.3464 0.5686
Schistosoma mansoni protein kinase 0.1301 0.3464 0.4697
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.1301 0.3464 0.3462
Trypanosoma brucei prostaglandin f synthase 0.0031 0.0063 0.017
Schistosoma mansoni sh3-containing grb2-like protein 1 (endophilin II) 0.0021 0.0036 0.0046
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.0031
Brugia malayi phosphofructokinase 0.0126 0.0317 0.0411
Entamoeba histolytica BAR/SH3 domain containing protein 0.0021 0.0036 0.0052
Loa Loa (eye worm) hypothetical protein 0.1301 0.3464 0.3462
Brugia malayi nuclear receptor NHR-88 0.0039 0.0084 0.0105
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0029 0.0037
Loa Loa (eye worm) hypothetical protein 0.012 0.0301 0.0297
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0016 0.0024 0.0057
Schistosoma mansoni lamin 0.0026 0.005 0.0067
Loa Loa (eye worm) TK protein kinase 0.1301 0.3464 0.3462
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Brugia malayi hypothetical protein 0.1301 0.3464 0.4531
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1301 0.3464 0.5686
Echinococcus multilocularis glutathione S transferase 0.0012 0.0011 0.001
Trypanosoma brucei protein kinase, putative 0.1301 0.3464 1
Loa Loa (eye worm) TK protein kinase 0.1301 0.3464 0.3462
Brugia malayi Probable tyrosine-protein kinase kin-31 0.1301 0.3464 0.4531
Schistosoma mansoni tensin-related 0.0981 0.2605 0.3532
Brugia malayi Protein kinase domain containing protein 0.2282 0.609 0.7969
Echinococcus granulosus UDP glucose 4 epimerase 0.0051 0.0115 0.0114
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0104 0.0102
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0012 0.0013 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0035 0.009
Schistosoma mansoni eps8-related protein 0.0021 0.0036 0.0046
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0035 0.0034
Schistosoma mansoni thyroid hormone receptor 0.0039 0.0084 0.0112
Entamoeba histolytica hypothetical protein 0.1301 0.3464 0.5686
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0071 1
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus multilocularis breast cancer anti estrogen resistance protein 0.0021 0.0036 0.0034
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0032
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0104 0.01
Echinococcus multilocularis protein kinase 0.1301 0.3464 0.3464
Echinococcus multilocularis tyrosine protein kinase csk 0.1301 0.3464 0.3464
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0013 0.0026
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0063 0.0061
Loa Loa (eye worm) hypothetical protein 0.1301 0.3464 0.3462
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0074 0.2096
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.0354 1
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0006 0.0004
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0023 0.1686
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0014 0.0013
Onchocerca volvulus 0.1301 0.3464 0.5686
Echinococcus granulosus expressed protein 0.0021 0.0036 0.0034
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0981 0.2605 0.4275
Leishmania major hypothetical protein, conserved 0.0021 0.0036 0.0091
Brugia malayi PAS domain containing protein 0.0048 0.0107 0.0135
Schistosoma mansoni protein kinase 0.1301 0.3464 0.4697
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0039 0.0084 0.0083
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0016 0.0024 0.0057
Loa Loa (eye worm) protein-tyrosine kinase 0.0021 0.0036 0.0032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0039 0.0084 0.008
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.0063 0.0077
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0039 0.0084 0.008
Echinococcus granulosus FTZ F1 alpha 0.0039 0.0084 0.0083
Schistosoma mansoni nuclear receptor 0.0018 0.0029 0.0037
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0012 0.0011 0.0022
Schistosoma mansoni Dab2-interacting protein-like 0.0021 0.0036 0.0046
Brugia malayi 6-phosphofructokinase 0.0126 0.0317 0.0411
Schistosoma mansoni hypothetical protein 0.0051 0.0115 0.0154
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0981 0.2605 0.4275
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0071 0.0194
Entamoeba histolytica tyrosine kinase, putative 0.1301 0.3464 0.5686
Brugia malayi Glutathione S-transferase 4 0.002 0.0033 0.0038
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Entamoeba histolytica tyrosine kinase, putative 0.1301 0.3464 0.5686
Echinococcus granulosus neuropeptide s receptor 0.0454 0.1194 0.1193
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0012 0.0013 0.0026
Onchocerca volvulus 0.0031 0.0063 0.0097
Toxoplasma gondii aldose reductase, putative 0.0031 0.0063 0.017
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0041 0.0107
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.1301 0.3464 0.3462
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.1301 0.3464 0.5686
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0745 0.2141
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0039 0.0084 0.008
Loa Loa (eye worm) hypothetical protein 0.1301 0.3464 0.3462
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.1301 0.3464 0.3464
Echinococcus granulosus SHC transforming protein 3 0.0981 0.2605 0.2604
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1301 0.3464 0.5686
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0013 0.0026
Schistosoma mansoni hypothetical protein 0.0981 0.2605 0.3532
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0035 0.009
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0177 0.0226
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0022 0.0052
Brugia malayi hypothetical protein 0.1301 0.3464 0.4531
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Brugia malayi cytokine inducible SH2-containing protein 5 0.0981 0.2605 0.3407
Loa Loa (eye worm) hypothetical protein 0.1301 0.3464 0.3462
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0006 0.0005
Loa Loa (eye worm) serine/threonine protein kinase 0.1301 0.3464 0.3462
Loa Loa (eye worm) hypothetical protein 0.0039 0.0084 0.008
Trichomonas vaginalis CAMK family protein kinase 0.1301 0.3464 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0177 0.0173
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0022
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0032
Loa Loa (eye worm) sex muscle abnormal protein 5 0.1001 0.2661 0.2658
Echinococcus granulosus tyrosine protein kinase Fyn 0.2303 0.6146 0.6145
Echinococcus granulosus signal transduction protein lnk realted 0.0981 0.2605 0.2604
Brugia malayi SH2 domain containing protein 0.0981 0.2605 0.3407
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0022
Schistosoma mansoni protein kinase 0.1301 0.3464 0.4697
Echinococcus granulosus expressed conserved protein 0.0981 0.2605 0.2604
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0981 0.2605 0.2604
Brugia malayi hypothetical protein 0.0018 0.0029 0.0033
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0063 0.017
Toxoplasma gondii 6-phosphofructokinase 0.0034 0.0071 0.0194
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0018 0.0029 0.0037
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0177 0.0173
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.1301 0.3464 0.3462
Brugia malayi Variant SH3 domain containing protein 0.1001 0.2661 0.3479
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0013 0.0026
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.1301 0.3464 0.3464
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0745 0.2141
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0039 0.0084 0.008
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0039 0.0084 0.0112
Loa Loa (eye worm) hypothetical protein 0.0039 0.0084 0.008
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0018 0.0014
Brugia malayi glutathione reductase 0.0046 0.0104 0.0131
Schistosoma mansoni hypothetical protein 0.0559 0.1477 0.2001
Loa Loa (eye worm) TK/ACK protein kinase 0.1301 0.3464 0.3462
Loa Loa (eye worm) oxidoreductase 0.0031 0.0063 0.0059
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0981 0.2605 0.2603
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0009
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.1301 0.3464 1
Loa Loa (eye worm) hypothetical protein 0.003 0.006 0.0056
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Echinococcus granulosus retinal guanylyl cyclase 2 0.1301 0.3464 0.3464
Loa Loa (eye worm) hypothetical protein 0.0981 0.2605 0.2603
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.005 0.0061
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0022 0.0053
Brugia malayi Tyrosine-protein kinase abl-1 0.2861 0.7641 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0039 0.0084 0.0105
Brugia malayi ecdysteroid receptor 0.0039 0.0084 0.0105
Trichomonas vaginalis guanylate cyclase, putative 0.0012 0.0013 0.0026
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0177 0.0175
Plasmodium falciparum thioredoxin reductase 0.0046 0.0104 0.0288
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0039 0.0084 0.0105
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0126 0.0317 0.0314
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0035 0.0041
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Loa Loa (eye worm) oxidoreductase 0.0031 0.0063 0.0059
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.0029 0.0028
Echinococcus granulosus dna polymerase eta 0.0021 0.0035 0.0034
Schistosoma mansoni dynamin-associated protein 0.0021 0.0036 0.0046
Trichomonas vaginalis aldo/keto reductase, putative 0.0031 0.0063 0.017
Brugia malayi Thioredoxin reductase 0.0046 0.0104 0.0131
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.2282 0.609 0.6089
Onchocerca volvulus 0.1301 0.3464 0.5686
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.1301 0.3464 0.3464
Entamoeba histolytica tyrosine kinase, putative 0.1301 0.3464 0.5686
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.1301 0.3464 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0026 0.0065
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0139 0.3858
Loa Loa (eye worm) hypothetical protein 0.1301 0.3464 0.3462
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0142 0.0191
Schistosoma mansoni protein kinase 0.1301 0.3464 0.4697
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Echinococcus granulosus microtubule associated protein 2 0.0675 0.1786 0.1785
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.1301 0.3464 0.4531
Echinococcus multilocularis dnaJ subfamily B 0.04 0.105 0.1049
Echinococcus multilocularis tyrosine protein kinase csk 0.1301 0.3464 0.3464
Echinococcus multilocularis glutathione S transferase 0.002 0.0033 0.0031
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1301 0.3464 0.3464
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0981 0.2605 0.2604
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0981 0.2605 0.2604
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0126 0.0317 0.4081
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0063 0.0061
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0012 0.0013 0.0026
Entamoeba histolytica hypothetical protein 0.1301 0.3464 0.5686
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0042 0.1088
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0018 0.0029 0.0028
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0074 0.0073
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0012 0.0011 0.0022
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Loa Loa (eye worm) RGC/RGC protein kinase 0.1301 0.3464 0.3462
Onchocerca volvulus 0.0035 0.0074 0.0115
Echinococcus granulosus growth factor receptor bound protein 2 0.1001 0.2661 0.266
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0063 0.017
Schistosoma mansoni RAR-like nuclear receptor 0.0039 0.0084 0.0112
Echinococcus granulosus tyrosine kinase 0.1301 0.3464 0.3464
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0039 0.0084 0.0083
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.1301 0.3464 0.3464
Trichomonas vaginalis conserved hypothetical protein 0.1301 0.3464 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0032
Onchocerca volvulus 0.0031 0.0063 0.0097
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0018 0.0029 0.0041
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Schistosoma mansoni GST class-mu 0.0032 0.0064 0.0085
Echinococcus multilocularis protein tyrosine kinase 0.1301 0.3464 0.3464
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0035 0.009
Trypanosoma brucei unspecified product 0.0021 0.0035 0.009
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1301 0.3464 0.5686
Entamoeba histolytica protein kinase, putative 0.0021 0.0036 0.0052
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Schistosoma mansoni run and tbc1 domain containing 0.0021 0.0036 0.0046
Echinococcus multilocularis NCK adaptor protein 0.1001 0.2661 0.266
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0029
Onchocerca volvulus Huntingtin homolog 0.012 0.0301 0.0487
Brugia malayi protein-tyrosine kinase 0.2282 0.609 0.7969
Echinococcus multilocularis activin receptor type 0.1301 0.3464 0.3464
Onchocerca volvulus 0.0021 0.0036 0.0052
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.1301 0.3464 0.3464
Loa Loa (eye worm) TK/FER protein kinase 0.1301 0.3464 0.3462
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0084 0.0083
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0009
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0091 0.0253
Entamoeba histolytica hypothetical protein 0.0021 0.0036 0.0052
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0021 0.0036 0.0032
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.1301 0.3464 0.5686
Loa Loa (eye worm) hypothetical protein 0.0039 0.0084 0.008
Plasmodium vivax glutathione reductase, putative 0.0046 0.0104 0.0288
Onchocerca volvulus 0.0981 0.2605 0.4275
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Schistosoma mansoni tyrosine kinase 0.2303 0.6146 0.8333
Echinococcus multilocularis tensin 0.0981 0.2605 0.2604
Trypanosoma cruzi aldo/keto reductase, putative 0.0031 0.0063 0.017
Schistosoma mansoni serine/threonine protein kinase 0.1301 0.3464 0.4697
Entamoeba histolytica protein kinase, putative 0.0981 0.2605 0.4275
Echinococcus granulosus tyrosine protein kinase csk 0.1301 0.3464 0.3464
Giardia lamblia Kinase, NEK 0.1301 0.3464 1
Echinococcus granulosus integrin linked protein kinase 0.1301 0.3464 0.3464
Brugia malayi Spectrin alpha chain 0.0021 0.0036 0.0041
Echinococcus multilocularis tyrosine protein kinase Srms 0.2282 0.609 0.6089
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0035 0.009
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1301 0.3464 0.3464
Echinococcus multilocularis glutathione S transferase 0.0012 0.0011 0.001
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0011 0.001
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0021 0.005
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0042 0.1088
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0023 0.0029
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0035 0.009
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0126 0.0317 0.0906
Brugia malayi SH2 domain containing protein 0.0981 0.2605 0.3407
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2303 0.6146 0.6145
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0981 0.2605 0.2604
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0013 0.0026
Loa Loa (eye worm) TK/FER protein kinase 0.1301 0.3464 0.3462
Brugia malayi Variant SH3 domain containing protein 0.0981 0.2605 0.3407
Loa Loa (eye worm) hypothetical protein 0.0981 0.2605 0.2603
Echinococcus multilocularis voltage gated potassium channel subunit 0.0009 0.0004 0.0002
Entamoeba histolytica SH2 domain containing protein 0.0981 0.2605 0.4275
Loa Loa (eye worm) hypothetical protein 0.186 0.4959 0.4957
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.0029 0.0028
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0031 0.0063 0.017
Entamoeba histolytica tyrosine kinase, putative 0.1301 0.3464 0.5686
Entamoeba histolytica tyrosine kinase, putative 0.1301 0.3464 0.5686
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Loa Loa (eye worm) variant SH3 domain-containing protein 0.1001 0.2661 0.2658
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0177 0.0238
Echinococcus multilocularis tyrosine protein kinase Blk 0.2282 0.609 0.6089
Entamoeba histolytica serine/threonine kinase, putative 0.1301 0.3464 0.5686
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus multilocularis slit robo rho gtpase activating protein 1 0.0021 0.0036 0.0034
Echinococcus multilocularis abhydrolase domain containing protein 0.0037 0.0079 0.0078
Brugia malayi STAT protein, DNA binding domain containing protein 0.0981 0.2605 0.3407
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.1301 0.3464 1
Loa Loa (eye worm) UDP galactose 4'-epimerase 0.0051 0.0115 0.0111
Schistosoma mansoni cell polarity protein 0.0021 0.0036 0.0046
Loa Loa (eye worm) TK/FER protein kinase 0.2282 0.609 0.6089
Echinococcus multilocularis musashi 0.0026 0.005 0.0049
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0745 0.2141
Onchocerca volvulus 0.2282 0.609 1
Schistosoma mansoni tyrosine kinase 0.2282 0.609 0.8258
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0039 0.0084 0.0112
Echinococcus multilocularis aldo keto reductase 0.0031 0.0063 0.0061
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0035 0.009
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0142 0.0359 0.0358
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1301 0.3464 0.3464
Trypanosoma cruzi aldo-keto reductase 0.0031 0.0063 0.017
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0023 0.054
Schistosoma mansoni serine/threonine RGC 0.1301 0.3464 0.4697
Trypanosoma cruzi protein kinase, putative 0.1301 0.3464 1
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.2303 0.6146 0.6145
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.2303 0.6146 0.6145
Loa Loa (eye worm) TK protein kinase 0.1301 0.3464 0.3462
Brugia malayi nuclear hormone receptor 0.0039 0.0084 0.0105
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0063 0.0061
Brugia malayi Immunoglobulin I-set domain containing protein 0.1301 0.3464 0.4531
Brugia malayi hypothetical protein 0.0148 0.0375 0.0486
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0063 0.0061
Entamoeba histolytica serine/threonine kinase, putative 0.1301 0.3464 0.5686
Brugia malayi hypothetical protein 0.016 0.0407 0.0528
Brugia malayi Furin-like cysteine rich region family protein 0.1301 0.3464 0.4531
Brugia malayi integrin-linked kinase 0.1301 0.3464 0.4531
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.1301 0.3464 0.3464
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Loa Loa (eye worm) guanylate kinase 0.0021 0.0036 0.0032
Echinococcus multilocularis N chimaerin 0.0981 0.2605 0.2604
Loa Loa (eye worm) hypothetical protein 0.0039 0.0084 0.008
Onchocerca volvulus 0.0232 0.0601 0.0982
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0084 0.0083
Loa Loa (eye worm) TK/ABL protein kinase 0.3743 1 1
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0082 0.0221
Echinococcus granulosus raf serine:threonine protein kinase 0.1301 0.3464 0.3464
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0035 0.009
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0016 0.0024 0.0057
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0071 0.0194
Echinococcus granulosus SH2 domain containing protein 7 0.0981 0.2605 0.2604
Entamoeba histolytica tyrosine kinase, putative 0.1301 0.3464 0.5686
Echinococcus multilocularis transfer RNA-Ala 0.0021 0.0036 0.0034
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1301 0.3464 0.5686
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.0317 0.0906
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Trichomonas vaginalis conserved hypothetical protein 0.1301 0.3464 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0024 0.0567
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0021 0.002
Loa Loa (eye worm) p53BP2 0.0021 0.0036 0.0032
Entamoeba histolytica tyrosine kinase, putative 0.1301 0.3464 0.5686
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0024 0.0567
Brugia malayi Pre-SET motif family protein 0.0204 0.0526 0.0684
Echinococcus granulosus tensin 0.0981 0.2605 0.2604
Echinococcus multilocularis kinase suppressor of Ras 1 0.1301 0.3464 0.3464
Brugia malayi nuclear receptor NHR-67 0.0018 0.0029 0.0033
Brugia malayi Cytochrome P450 family protein 0.0022 0.0039 0.0046
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.1301 0.3464 1
Echinococcus multilocularis 0.0981 0.2605 0.2604
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0035 0.009
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0071 0.0194
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0107 0.0143
Echinococcus granulosus epidermal growth factor receptor 0.1301 0.3464 0.3464
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0024 0.0567
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0071 0.0194
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0042 0.0062
Loa Loa (eye worm) DR-78 0.0018 0.0029 0.0025
Echinococcus granulosus src region 0.0021 0.0036 0.0034
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.2303 0.6146 0.6145
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0039 0.0035
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0023 0.0643
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0063 0.017
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0006 0.0002
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0262 0.7387
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0981 0.2605 0.2604
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Loa Loa (eye worm) protein kinase domain-containing protein 0.1301 0.3464 0.3462
Brugia malayi tRNA modification GTPase TrmE family protein 0.0981 0.2605 0.3407
Echinococcus multilocularis heat shock protein 70 0.1301 0.3464 0.3464
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0023 0.0055
Loa Loa (eye worm) hypothetical protein 0.1301 0.3464 0.3462
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0117 0.0294 0.8288
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus granulosus rho guanine nucleotide exchange factor 7 0.0021 0.0036 0.0034
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0036 0.0041
Schistosoma mansoni Glutathione S-transferase 28 kDa (GST 28) (GST class-mu) 0.0032 0.0064 0.0085
Echinococcus granulosus hypothetical protein 0.0031 0.0063 0.0061
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Mycobacterium tuberculosis Probable reductase 0.0105 0.0262 0.7387
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0104 0.0102
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0042 0.1185
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0036 0.0041
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2303 0.6146 0.6145
Brugia malayi Nuclear hormone receptor E75 0.0018 0.0029 0.0033
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0063 0.017
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0012 0.0013 0.0012
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0012 0.0013 0.0012
Echinococcus granulosus tyrosine protein kinase Fps85D 0.2282 0.609 0.6089
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0981 0.2605 0.3532
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0032
Mycobacterium tuberculosis Probable oxidoreductase 0.0031 0.0063 0.1684
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0031 0.0063 0.017
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Loa Loa (eye worm) hypothetical protein 0.1301 0.3464 0.3462
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0035 0.0031
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0042 0.011
Brugia malayi Pre-SET motif family protein 0.003 0.006 0.0073
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0012 0.0013 0.0026
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0034 0.0071 0.0669
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0035 0.0041
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.1301 0.3464 0.5686
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1301 0.3464 0.5686
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0262 0.7387
Echinococcus granulosus intersectin 2 0.0021 0.0036 0.0034
Mycobacterium leprae Possible regulatory protein 0.0012 0.0013 0.026
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0039 0.0084 0.0112
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus multilocularis endophilin A3 0.0021 0.0036 0.0034
Echinococcus multilocularis lamin 0.0026 0.005 0.0049
Brugia malayi SH3 domain containing protein 0.0021 0.0036 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.1301 0.3464 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0262 0.7387
Echinococcus multilocularis tyrosine protein kinase Abl 0.2861 0.7641 0.764
Echinococcus multilocularis tensin 0.0981 0.2605 0.2604
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0021 0.005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.006 0.0079
Echinococcus multilocularis SH2 motif 0.0981 0.2605 0.2604
Schistosoma mansoni sorting nexin 0.0021 0.0036 0.0046
Onchocerca volvulus 0.0081 0.0197 0.0318
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0026 0.2284
Echinococcus granulosus epidermal growth factor receptor kinase 0.0021 0.0036 0.0034
Schistosoma mansoni C-fyn 0.0021 0.0036 0.0046
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0063 0.0061
Entamoeba histolytica UDP-glucose 4-epimerase, putative 0.0051 0.0115 0.0183
Entamoeba histolytica tyrosine kinase, putative 0.1301 0.3464 0.5686
Echinococcus multilocularis neuropeptide receptor A26 0.0454 0.1194 0.1193
Onchocerca volvulus 0.0981 0.2605 0.4275
Loa Loa (eye worm) hypothetical protein 0.1001 0.2661 0.2658
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0039 0.0084 0.0105
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0021 0.005
Loa Loa (eye worm) TK/ROR protein kinase 0.1301 0.3464 0.3462
Entamoeba histolytica cysteine surface protein, putative 0.1301 0.3464 0.5686
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0082 0.0226
Onchocerca volvulus 0.0021 0.0036 0.0052
Echinococcus multilocularis FTZ F1 alpha 0.0039 0.0084 0.0083
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.006 0.0079
Loa Loa (eye worm) SH2 domain-containing protein 0.0981 0.2605 0.2603
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0018 0.0041
Toxoplasma gondii elongation factor 1-gamma, putative 0.0016 0.0024 0.0057
Echinococcus granulosus dna polymerase kappa 0.0021 0.0035 0.0034
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0012 0.0011 0.0022
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0026 0.0065
Echinococcus granulosus activin receptor type 0.1301 0.3464 0.3464
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Echinococcus granulosus abhydrolase domain containing protein 0.0037 0.0079 0.0078
Trichomonas vaginalis TK family protein kinase 0.1301 0.3464 1
Onchocerca volvulus 0.0031 0.0063 0.0097
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.2303 0.6146 0.6145
Onchocerca volvulus 0.0981 0.2605 0.4275
Onchocerca volvulus Bile acid receptor homolog 0.0039 0.0084 0.0132
Loa Loa (eye worm) hypothetical protein 0.0039 0.0084 0.008
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0034 0.0071 0.0194
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0021 0.0036 0.0034
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.1301 0.3464 0.4531
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0084 0.0083
Echinococcus granulosus dual specificity testis-specific protein kinase 0.1301 0.3464 0.3464
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0043 0.0112
Echinococcus granulosus aldo keto reductase 0.0031 0.0063 0.0061
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0091 0.009
Loa Loa (eye worm) hypoxia-induced factor 1 0.0147 0.0374 0.037
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0039 0.0084 0.0083
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.1301 0.3464 1
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0031 0.0063 0.017
Brugia malayi glutathione transferase 0.0194 0.0498 0.0648
Schistosoma mansoni protein kinase 0.1301 0.3464 0.4697
Brugia malayi ecdysone receptor 0.0018 0.0029 0.0033
Echinococcus granulosus retinal guanylyl cyclase 2 0.1301 0.3464 0.3464
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0042 0.0062
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0012 0.0013 0.0026
Echinococcus multilocularis aldo keto reductase 0.0031 0.0063 0.0061
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1301 0.3464 0.3464
Trichomonas vaginalis protein tyrosine kinase, putative 0.1301 0.3464 1
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus multilocularis aldo keto reductase 0.0031 0.0063 0.0061
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus granulosus hematopoietic lineage cell specific protein 0.0021 0.0036 0.0034
Brugia malayi Guanylate kinase family protein 0.0021 0.0036 0.0041
Entamoeba histolytica hypothetical protein, conserved 0.0021 0.0036 0.0052
Loa Loa (eye worm) RGC/RGC protein kinase 0.1301 0.3464 0.3462
Echinococcus granulosus aldo keto reductase 0.0031 0.0063 0.0061
Echinococcus multilocularis expressed protein 0.0021 0.0036 0.0034
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0042 0.1185
Echinococcus multilocularis eukaryotic translation elongation factor 1 0.0016 0.0024 0.0022
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.0526 0.0523
Loa Loa (eye worm) TK/FER protein kinase 0.2282 0.609 0.6089
Echinococcus granulosus ecdysone induced protein 78C 0.0039 0.0084 0.0083
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0074 0.0092
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0021 0.0027
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0042 0.1185
Loa Loa (eye worm) hypothetical protein 0.0039 0.0084 0.008
Schistosoma mansoni DNA polymerase eta 0.0021 0.0035 0.0046
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0023 0.0055
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0036 0.0091
Echinococcus granulosus breast cancer anti estrogen resistance protein 0.0021 0.0036 0.0034
Giardia lamblia Fructose-bisphosphate aldolase 0.0286 0.0745 0.2137
Echinococcus granulosus protein tyrosine kinase 0.1301 0.3464 0.3464
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.0031
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0029 0.0038
Schistosoma mansoni growth factor receptor-bound protein 0.1001 0.2661 0.3607
Schistosoma mansoni tyrosine kinase 0.2762 0.7374 1
Schistosoma mansoni suppressor of cytokine signaling 0.0981 0.2605 0.3532
Loa Loa (eye worm) hypothetical protein 0.0023 0.0042 0.0038
Brugia malayi follicle stimulating hormone receptor 0.0229 0.0592 0.077
Loa Loa (eye worm) acetyltransferase 0.0142 0.0359 0.0355
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0035 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0039 0.0084 0.0105
Brugia malayi Receptor family ligand binding region containing protein 0.1301 0.3464 0.4531
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0013 0.0026
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.1301 0.3464 0.4697
Trypanosoma brucei unspecified product 0.0014 0.0018 0.0041
Entamoeba histolytica serine/threonine kinase, putative 0.1301 0.3464 0.5686
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0981 0.2605 0.4275
Brugia malayi Protein kinase domain containing protein 0.2282 0.609 0.7969
Loa Loa (eye worm) TK/Met protein kinase 0.1301 0.3464 0.3462
Echinococcus granulosus tyrosine protein kinase Lyn 0.2303 0.6146 0.6145
Loa Loa (eye worm) TK/FER protein kinase 0.2282 0.609 0.6089
Schistosoma mansoni src-type protein tyrosine kinase-related 0.1301 0.3464 0.4697
Echinococcus granulosus dnaJ subfamily B 0.04 0.105 0.1049
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.1301 0.3464 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0023 0.0055
Echinococcus multilocularis SH2 domain containing protein 7 0.0981 0.2605 0.2604
Entamoeba histolytica tyrosine kinase, putative 0.1301 0.3464 0.5686
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0018 0.0029 0.0028
Entamoeba histolytica hypothetical protein, conserved 0.1301 0.3464 0.5686
Brugia malayi steroid hormone receptor 0.0039 0.0084 0.0105
Loa Loa (eye worm) hypothetical protein 0.0981 0.2605 0.2603
Entamoeba histolytica hypothetical protein 0.0035 0.0074 0.0115
Trypanosoma cruzi UDP-galactose 4-epimerase 0.0051 0.0115 0.0322
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.1301 0.3464 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0082 0.0129
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.1301 0.3464 0.4697
Loa Loa (eye worm) TK/DDR protein kinase 0.1301 0.3464 0.3462
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0041 0.1063
Leishmania major DNA polymerase kappa, putative 0.0021 0.0035 0.009
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0035 0.009
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0177 0.0238
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Echinococcus granulosus glutathione S transferase 0.0012 0.0011 0.001
Echinococcus granulosus tyrosine protein kinase Blk 0.2282 0.609 0.6089
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0036 0.0091
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0041 1
Leishmania major udp-glc 4-epimerase, putative 0.0049 0.011 0.0308
Onchocerca volvulus Putative cortactin 0.0021 0.0036 0.0052
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0025
Echinococcus granulosus tyrosine protein kinase Fyn 0.2303 0.6146 0.6145
Leishmania major protein kinase, putative 0.1301 0.3464 1
Echinococcus granulosus tyrosine protein kinase HCK 0.1301 0.3464 0.3464
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0035 0.009
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.1301 0.3464 0.3464
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0063 0.0061
Echinococcus granulosus aryl hydrocarbon receptor 0.0012 0.0013 0.0012
Treponema pallidum fructose-bisphosphate aldolase 0.0286 0.0745 1
Trypanosoma brucei unspecified product 0.0014 0.0018 0.0041
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0177 0.0238
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0126 0.0317 0.8967
Schistosoma mansoni coup transcription factor 0.0039 0.0084 0.0112
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Loa Loa (eye worm) hypothetical protein 0.1301 0.3464 0.3462
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0142 0.0359 0.0485
Echinococcus granulosus lamin 0.0026 0.005 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0039 0.0084 0.0105
Echinococcus granulosus Spectrin alpha actinin 0.0021 0.0036 0.0034
Onchocerca volvulus 0.2282 0.609 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.006 0.0058
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0084 0.0112
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0139 0.3925
Echinococcus multilocularis epidermal growth factor receptor 0.1301 0.3464 0.3464
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.1301 0.3464 1
Brugia malayi TAR-binding protein 0.0073 0.0177 0.0226
Brugia malayi nuclear hormone receptor family member odr-7 0.0018 0.0029 0.0033
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.2303 0.6146 0.6145
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0035 0.009
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0023 0.0643
Loa Loa (eye worm) hypothetical protein 0.1301 0.3464 0.3462
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1301 0.3464 0.5686
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0043 0.0112
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.1301 0.3464 0.4531
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.1301 0.3464 0.3464
Onchocerca volvulus Huntingtin homolog 0.012 0.0301 0.0487
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0042 0.011
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0981 0.2605 0.2603
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0016 0.0024 0.0057
Onchocerca volvulus 0.0012 0.0013 0.0015
Schistosoma mansoni tyrosine-protein kinase fps85d 0.1301 0.3464 0.4697
Schistosoma mansoni nuclear receptor 0.0018 0.0029 0.0037
Loa Loa (eye worm) TK/FER protein kinase 0.2282 0.609 0.6089
Onchocerca volvulus 0.1301 0.3464 0.5686
Brugia malayi hypothetical protein 0.012 0.0301 0.0388
Echinococcus multilocularis tyrosine kinase 0.1301 0.3464 0.3464
Entamoeba histolytica hypothetical protein 0.0023 0.0041 0.0061
Onchocerca volvulus 0.0021 0.0036 0.0052
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0025
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0039 0.0084 0.0083
Schistosoma mansoni retinoic acid receptor RXR 0.0039 0.0084 0.0112
Schistosoma mansoni thyroid hormone receptor 0.0039 0.0084 0.0112
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Onchocerca volvulus 0.1301 0.3464 0.5686
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus multilocularis activated cdc42 kinase 1 0.1301 0.3464 0.3464
Schistosoma mansoni tyrosine kinase 0.2303 0.6146 0.8333
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0025
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0023 0.0049
Loa Loa (eye worm) 6-phosphofructokinase 0.0126 0.0317 0.0314
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.1301 0.3464 1
Loa Loa (eye worm) RNA binding protein 0.0073 0.0177 0.0173
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0012 0.0011 0.0022
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0032
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1301 0.3464 0.3464
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0071 0.0194
Echinococcus granulosus tyrosine protein kinase Btk29A 0.2303 0.6146 0.6145
Onchocerca volvulus 0.2282 0.609 1
Schistosoma mansoni adapter molecule crk 0.1001 0.2661 0.3607
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.0317 0.0515
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.0031
Onchocerca volvulus 0.0981 0.2605 0.4275
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0024 0.0567
Echinococcus multilocularis glutathione S transferase 0.0032 0.0064 0.0063
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Echinococcus granulosus retinal guanylyl cyclase 2 0.1301 0.3464 0.3464
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0035 0.009
Loa Loa (eye worm) TK/FER protein kinase 0.2282 0.609 0.6089
Schistosoma mansoni suppressor of cytokine signaling 0.0981 0.2605 0.3532
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0036 0.0041
Loa Loa (eye worm) TK protein kinase 0.1301 0.3464 0.3462
Brugia malayi hypothetical protein 0.0035 0.0074 0.0092
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0016 0.0024 0.0057
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0041 0.0107
Schistosoma mansoni serine/threonine protein kinase 0.1322 0.352 0.4772
Onchocerca volvulus 0.002 0.0033 0.0048
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Entamoeba histolytica tyrosine kinase, putative 0.1301 0.3464 0.5686
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0023 0.0055
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0006 0.0002
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0981 0.2605 0.3532
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Plasmodium falciparum glutathione S-transferase 0.0032 0.0064 0.0175
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0745 0.2141
Entamoeba histolytica aldose reductase, putative 0.0031 0.0063 0.0097
Brugia malayi nuclear hormone receptor family member nhr-6 0.0018 0.0029 0.0033
Onchocerca volvulus 0.2282 0.609 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0035 0.0034
Leishmania major protein kinase, putative 0.0012 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0148 0.0375 0.0372
Schistosoma mansoni apoptosis stimulating of P53 0.0021 0.0036 0.0046
Entamoeba histolytica hypothetical protein 0.0021 0.0036 0.0052
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.1001 0.2661 0.3607
Brugia malayi SH2 domain containing protein 0.2282 0.609 0.7969
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0063 0.0061
Leishmania major protein kinase, putative 0.0012 0.0013 0.0026
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0006 0.0004
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0117 0.0294 0.8288
Schistosoma mansoni slit-robo rho gtpase activating protein 0.0021 0.0036 0.0046
Plasmodium vivax elongation factor 1-gamma, putative 0.0016 0.0024 0.0057
Entamoeba histolytica hypothetical protein 0.0021 0.0036 0.0052
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0981 0.2605 0.2604
Mycobacterium ulcerans oxidoreductase 0.0031 0.0063 0.1775
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.1301 0.3464 0.3462
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0104 0.0288
Schistosoma mansoni nuclear receptor nhr-48 0.0018 0.0029 0.0037
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.0354 1
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.0063 0.0077
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0032
Trypanosoma brucei trypanothione reductase 0.0046 0.0104 0.0288
Echinococcus multilocularis thyroid hormone receptor alpha 0.0039 0.0084 0.0083
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0006 0.0004
Loa Loa (eye worm) TK/FER protein kinase 0.2282 0.609 0.6089
Trichomonas vaginalis set domain proteins, putative 0.0232 0.0601 0.1727
Schistosoma mansoni vav2 0.0981 0.2605 0.3532
Echinococcus multilocularis epidermal growth factor receptor 0.1301 0.3464 0.3464
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.2282 0.609 0.6089
Loa Loa (eye worm) hypothetical protein 0.1301 0.3464 0.3462
Onchocerca volvulus 0.0031 0.0063 0.0097
Brugia malayi Protein kinase domain containing protein 0.2282 0.609 0.7969
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.1301 0.3464 0.4531
Echinococcus multilocularis aldehyde reductase 0.0022 0.0039 0.0037
Onchocerca volvulus 0.1301 0.3464 0.5686
Echinococcus multilocularis ecdysone induced protein 78C 0.0039 0.0084 0.0083
Echinococcus multilocularis tyrosine protein kinase pr2 0.1301 0.3464 0.3464
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0013 0.0028
Plasmodium falciparum thioredoxin reductase 0.0016 0.0023 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0036 0.0091
Loa Loa (eye worm) TK protein kinase 0.1301 0.3464 0.3462
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0035 0.009
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0013 0.0028
Echinococcus granulosus N chimaerin 0.0981 0.2605 0.2604
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0036 0.0041
Brugia malayi Peripheral plasma membrane protein CASK 0.0021 0.0036 0.0041
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0981 0.2605 0.2603
Loa Loa (eye worm) SH2 domain-containing protein 0.0981 0.2605 0.2603
Giardia lamblia UDP-glucose 4-epimerase 0.0049 0.011 0.0302
Echinococcus multilocularis nuclear receptor nhr 48 0.0018 0.0029 0.0028
Loa Loa (eye worm) hydrolase 0.0037 0.0079 0.0075
Loa Loa (eye worm) TK/FER protein kinase 0.1301 0.3464 0.3462
Onchocerca volvulus 0.0023 0.0042 0.0062
Loa Loa (eye worm) glutathione reductase 0.0046 0.0104 0.01
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0981 0.2605 0.3532
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Echinococcus multilocularis aldo keto reductase 0.0031 0.0063 0.0061
Brugia malayi bone morphogenetic protein type 1 receptor 0.1301 0.3464 0.4531
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0035 0.009
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0117 0.0294 0.8288
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0139 0.039
Schistosoma mansoni DNA helicase recq1 0.001 0.0006 0.0006
Entamoeba histolytica tyrosin kinase, putative 0.1301 0.3464 0.5686
Trypanosoma cruzi paraflagellar rod protein 5, putative 0.0021 0.0036 0.0091
Echinococcus multilocularis dna polymerase eta 0.0021 0.0035 0.0034
Onchocerca volvulus 0.0018 0.0029 0.0041
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1301 0.3464 0.3462
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.0031
Schistosoma mansoni hypothetical protein 0.1301 0.3464 0.4697
Loa Loa (eye worm) hypothetical protein 0.0023 0.0042 0.0038
Plasmodium vivax tyrosine kinase-like protein, putative 0.1301 0.3464 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0042 0.0038
Onchocerca volvulus 0.1301 0.3464 0.5686
Schistosoma mansoni nck2/grb4 0.1001 0.2661 0.3607
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0042 0.0062
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0009
Onchocerca volvulus Protein ultraspiracle homolog 0.0039 0.0084 0.0132
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0021 0.002
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Onchocerca volvulus 0.0026 0.005 0.0077
Brugia malayi conserved hypotetical protein 0.0018 0.0029 0.0033
Entamoeba histolytica hypothetical protein 0.0035 0.0074 0.0115
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0021 0.005
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0023 0.0055
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0021 0.005
Schistosoma mansoni serine/threonine protein kinase 0.1301 0.3464 0.4697
Echinococcus granulosus bloom syndrome protein 0.0023 0.0043 0.0041
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0042 0.1185
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Onchocerca volvulus Tyrosine kinase homolog 0.1301 0.3464 0.5686
Loa Loa (eye worm) hypothetical protein 0.0039 0.0084 0.008
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0002
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0262 0.7387
Schistosoma mansoni signal transducing adapter molecule (stam) 0.0021 0.0036 0.0046
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0016 0.0024 0.0057
Loa Loa (eye worm) RGC/RGC protein kinase 0.1301 0.3464 0.3462
Entamoeba histolytica tyrosin kinase, putative 0.1301 0.3464 0.5686
Echinococcus granulosus histone acetyltransferase KAT2B 0.0138 0.0349 0.0347
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0023 0.0055
Echinococcus granulosus receptor type guanylyl cyclase 0.1301 0.3464 0.3464
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0016 0.0024 0.0057
Entamoeba histolytica tyrosin kinase, putative 0.1301 0.3464 0.5686
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0042 0.1088
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.2303 0.6146 0.8333
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0012 0.0011 0.0022
Schistosoma mansoni hypothetical protein 0.0035 0.0074 0.0098
Mycobacterium ulcerans 6-phosphofructokinase 0.0126 0.0317 0.8979
Loa Loa (eye worm) hypothetical protein 0.0981 0.2605 0.2603
Brugia malayi Steroid receptor seven-up type 2 0.0039 0.0084 0.0105
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0023 0.0055
Echinococcus granulosus nostrin 0.0021 0.0036 0.0034
Echinococcus multilocularis tyrosine protein kinase Src42A 0.2303 0.6146 0.6145
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Schistosoma mansoni glutathione-S-transferase 0.0032 0.0064 0.0085
Echinococcus granulosus tyrosine protein kinase csk 0.1301 0.3464 0.3464
Schistosoma mansoni 6-phosphofructokinase 0.0126 0.0317 0.0429
Trichomonas vaginalis conserved hypothetical protein 0.1301 0.3464 1
Onchocerca volvulus 0.1301 0.3464 0.5686
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0006 0.0003
Onchocerca volvulus 0.0018 0.0029 0.0041
Toxoplasma gondii STE kinase 0.1301 0.3464 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0063 0.0061
Echinococcus multilocularis growth factor receptor bound protein 2 0.1001 0.2661 0.266
Schistosoma mansoni GTPase activating protein 0.0981 0.2605 0.3532
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0006 0.0004
Echinococcus granulosus glutathione S transferase 0.0012 0.0011 0.001
Echinococcus multilocularis tyrosine kinase 0.2282 0.609 0.6089
Schistosoma mansoni tensin 0.0981 0.2605 0.3532
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0021 0.0036 0.0034
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0745 0.2141
Echinococcus granulosus SH2 domain containing adapter protein F 0.0981 0.2605 0.2604
Brugia malayi UDP galactose 4'-epimerase 0.0051 0.0115 0.0146
Brugia malayi Protein kinase domain containing protein 0.2282 0.609 0.7969
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0036 0.0041
Loa Loa (eye worm) hypothetical protein 0.0981 0.2605 0.2603
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.0031
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.006 0.0058
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.0317 0.0906
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0023 0.0055
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0018 0.0029 0.0028
Plasmodium falciparum epoxide hydrolase 1 0.0037 0.0079 0.0217
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Trichomonas vaginalis conserved hypothetical protein 0.1301 0.3464 1
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0981 0.2605 0.2604
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0042 0.1088
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0042 0.005
Brugia malayi Variant SH3 domain containing protein 0.0981 0.2605 0.3407
Giardia lamblia Kinase, NEK 0.1301 0.3464 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0018 0.0041
Brugia malayi hypoxia-induced factor 1 0.0147 0.0374 0.0485
Echinococcus multilocularis signal transduction protein lnk realted 0.0981 0.2605 0.2604
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0039 0.0084 0.0083
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0031 0.0063 0.017
Brugia malayi C-terminal src kinase protein 1 0.1301 0.3464 0.4531
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0035 0.009
Trichomonas vaginalis UDP-glucose 4-epimerase, putative 0.0051 0.0115 0.0322
Schistosoma mansoni cpg binding protein 0.0028 0.0055 0.0073
Brugia malayi hypothetical protein 0.0981 0.2605 0.3407
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Giardia lamblia Aldose reductase 0.0031 0.0063 0.0165
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1301 0.3464 0.5686
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0139 0.039
Echinococcus granulosus tyrosine protein kinase shark 0.2282 0.609 0.6089
Loa Loa (eye worm) oxidoreductase 0.0031 0.0063 0.0059
Entamoeba histolytica ankyrin repeat protein 0.1301 0.3464 0.5686
Loa Loa (eye worm) TK/FER protein kinase 0.1301 0.3464 0.3462
Echinococcus multilocularis intersectin 2 0.0021 0.0036 0.0034
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0262 0.7387
Mycobacterium ulcerans hypothetical protein 0.0023 0.0042 0.1185
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0286 0.0745 0.1217
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.0317 0.0515
Echinococcus granulosus ephrin type A receptor 4 A 0.1301 0.3464 0.3464
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0134 0.0377
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Onchocerca volvulus 0.0026 0.005 0.0077
Echinococcus granulosus tyrosine protein kinase Src42A 0.0981 0.2605 0.2604
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0029 0.0028
Schistosoma mansoni shc transforming protein 0.0981 0.2605 0.3532
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Brugia malayi protein-tyrosine kinase 0.0021 0.0036 0.0041
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Trichomonas vaginalis glutaminyl-tRNA synthetase, putative 0.002 0.0033 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0036 0.0091
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0139 0.0137
Schistosoma mansoni signal transduction protein lnk-related 0.0981 0.2605 0.3532
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus multilocularis prostaglandin H2 D isomerase 0.0032 0.0064 0.0063
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Trypanosoma brucei conserved protein 0.0021 0.0036 0.0091
Loa Loa (eye worm) TK protein kinase 0.1301 0.3464 0.3462
Brugia malayi CXXC zinc finger family protein 0.0028 0.0055 0.0067
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0035 0.009
Echinococcus multilocularis SH2 motif 0.0981 0.2605 0.2604
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0023 0.0021
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0063 0.017
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0025
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0021 0.005
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0023 0.0055
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0042 0.005
Echinococcus multilocularis transfer RNA-Thr 0.1301 0.3464 0.3464
Entamoeba histolytica hypothetical protein 0.0021 0.0036 0.0052
Echinococcus multilocularis SH2 motif 0.0981 0.2605 0.2604
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0035 0.0041
Schistosoma mansoni microtubule-associated protein tau 0.0675 0.1786 0.242
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0041 0.0254
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Echinococcus granulosus prostaglandin H2 D isomerase 0.0032 0.0064 0.0063
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0023 0.0055
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Leishmania major hypothetical protein, conserved 0.0012 0.0011 0.0022
Entamoeba histolytica BAR/SH3 domain containing protein 0.0021 0.0036 0.0052
Echinococcus multilocularis UDP glucose 4 epimerase 0.0051 0.0115 0.0114
Schistosoma mansoni tyrosine protein kinase 0.1301 0.3464 0.4697
Schistosoma mansoni hypothetical protein 0.0021 0.0036 0.0046
Trichomonas vaginalis p67phox protein, putative 0.0021 0.0036 0.0091
Schistosoma mansoni tensin-related 0.0981 0.2605 0.3532
Entamoeba histolytica ankyrin repeat protein 0.1301 0.3464 0.5686
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0012 0.0013 0.0026
Echinococcus granulosus glutathione S transferase 0.002 0.0033 0.0031
Mycobacterium tuberculosis Probable oxidoreductase 0.0117 0.0294 0.8288
Loa Loa (eye worm) hypothetical protein 0.016 0.0407 0.0403
Onchocerca volvulus 0.0031 0.0063 0.0097
Loa Loa (eye worm) hypothetical protein 0.0194 0.0498 0.0495
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.0354 1
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.003 0.0061 0.0166
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0029 0.0028
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0035 0.009
Brugia malayi Tensin 0.0981 0.2605 0.3407
Schistosoma mansoni lamin 0.0026 0.005 0.0067
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0035 0.0894
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0139 0.0186
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0018 0.0029 0.0037
Entamoeba histolytica hypothetical protein 0.1301 0.3464 0.5686
Brugia malayi isocitrate dehydrogenase 0.0015 0.0021 0.0023
Echinococcus granulosus thyroid hormone receptor alpha 0.0018 0.0029 0.0028
Echinococcus granulosus NCK adaptor protein 0.1001 0.2661 0.266
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0023 0.0055
Loa Loa (eye worm) hypothetical protein 0.0981 0.2605 0.2603
Loa Loa (eye worm) intermediate filament protein 0.0026 0.005 0.0047
Loa Loa (eye worm) TK/EGFR protein kinase 0.1301 0.3464 0.3462
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0041 0.4838
Echinococcus multilocularis lamin dm0 0.0026 0.005 0.0049
Schistosoma mansoni tensin 0.0981 0.2605 0.3532
Echinococcus granulosus tyrosine protein kinase Srms 0.2282 0.609 0.6089
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.1301 0.3464 1
Echinococcus multilocularis tyrosine protein kinase Fgr 0.2303 0.6146 0.6145
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.0029 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0035 0.009
Trypanosoma cruzi elongation factor 1-gamma (EF-1-gamma), putative 0.0012 0.0011 0.0022
Onchocerca volvulus 0.0981 0.2605 0.4275
Mycobacterium ulcerans hypothetical protein 0.0009 0.0004 0.0109
Toxoplasma gondii thioredoxin reductase 0.0046 0.0104 0.0288
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0031 0.0063 0.0061
Echinococcus granulosus cpg binding protein 0.003 0.0059 0.0058
Echinococcus multilocularis ephrin type A receptor 4 A 0.1301 0.3464 0.3464
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0025
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0032
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0014 0.0013
Entamoeba histolytica hypothetical protein 0.0021 0.0036 0.0052
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0035 0.0993
Brugia malayi Immunoglobulin I-set domain containing protein 0.1301 0.3464 0.4531
Onchocerca volvulus 0.0148 0.0375 0.061
Loa Loa (eye worm) hypothetical protein 0.1301 0.3464 0.3462
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0039 0.0084 0.0132
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0197 0.0194
Schistosoma mansoni protein kinase 0.1301 0.3464 0.4697
Brugia malayi nuclear receptor RXR 0.0021 0.0035 0.0041
Brugia malayi RNA binding protein 0.0073 0.0177 0.0226
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0084 0.0105
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1301 0.3464 0.5686
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0074 0.0073
Echinococcus multilocularis aryl hydrocarbon receptor 0.0012 0.0013 0.0012
Echinococcus granulosus tyrosine protein kinase Fyn 0.2303 0.6146 0.6145
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0071 0.0194
Loa Loa (eye worm) RecQ helicase 0.0023 0.0043 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0039 0.0084 0.0105
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0031 0.0063 0.0077
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1301 0.3464 0.5686
Brugia malayi Raf kinase 0.1301 0.3464 0.4531
Echinococcus granulosus epidermal growth factor receptor 0.1301 0.3464 0.3464
Loa Loa (eye worm) TK protein kinase 0.1301 0.3464 0.3462
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0035 0.009
Brugia malayi acetyltransferase, GNAT family protein 0.0142 0.0359 0.0465
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0023 0.0055
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0745 0.2141
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.0021 0.0496
Entamoeba histolytica hypothetical protein 0.1301 0.3464 0.5686
Brugia malayi Fes/CIP4 homology domain containing protein 0.0021 0.0036 0.0041
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0006 0.0003
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0036 0.0041
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0012 0.0013 0.0026
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.1301 0.3464 0.3464
Entamoeba histolytica hypothetical protein 0.1301 0.3464 0.5686
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0042 0.011
Schistosoma mansoni SH2A 0.0981 0.2605 0.3532
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0071 0.0194
Giardia lamblia Kinase 0.1301 0.3464 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0011 0.001
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0177 0.0238
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.006 0.0079
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.005 0.0047
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0981 0.2605 0.2604
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0039 0.0084 0.0105
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Brugia malayi Tyrosine-protein kinase PR2 0.1301 0.3464 0.4531
Loa Loa (eye worm) hypothetical protein 0.0981 0.2605 0.2603
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0035 0.0051
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0035 0.0046
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Loa Loa (eye worm) TK/FER protein kinase 0.2282 0.609 0.6089
Toxoplasma gondii protein kinase 0.1301 0.3464 1
Trypanosoma brucei UDP-galactose 4-epimerase 0.0049 0.011 0.0308
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Schistosoma mansoni tyrosine kinase 0.2303 0.6146 0.8333
Echinococcus granulosus activated cdc42 kinase 1 0.1301 0.3464 0.3464
Brugia malayi Variant SH3 domain containing protein 0.1001 0.2661 0.3479
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0197 0.0196
Echinococcus granulosus suppressor of cytokine signaling 7 0.0981 0.2605 0.2604
Echinococcus multilocularis 6 phosphofructokinase 0.0126 0.0317 0.0316
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0074 0.0098
Entamoeba histolytica tyrosin kinase, putative 0.1301 0.3464 0.5686
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0021 0.002
Brugia malayi Myosin tail family protein 0.0021 0.0036 0.0041
Entamoeba histolytica hypothetical protein 0.0035 0.0074 0.0115
Schistosoma mansoni sorbin 0.0021 0.0036 0.0046
Loa Loa (eye worm) hypothetical protein 0.0981 0.2605 0.2603
Schistosoma mansoni protein kinase 0.1301 0.3464 0.4697
Schistosoma mansoni protein kinase 0.1301 0.3464 0.4697
Entamoeba histolytica serine/threonine kinase, putative 0.1301 0.3464 0.5686
Brugia malayi 6-phosphofructokinase 0.0126 0.0317 0.0411
Schistosoma mansoni serine/threonine protein kinase 0.1301 0.3464 0.4697
Entamoeba histolytica tyrosine kinase, putative 0.1301 0.3464 0.5686
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.1301 0.3464 0.3464
Loa Loa (eye worm) hypothetical protein 0.0031 0.0063 0.0059
Giardia lamblia Aldose reductase 0.0031 0.0063 0.0165
Loa Loa (eye worm) hypothetical protein 0.0981 0.2605 0.2603
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0023 0.0055
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0021 0.0017
Plasmodium falciparum glutathione reductase 0.0046 0.0104 0.0288
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0126 0.0317 0.0906
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Echinococcus granulosus tyrosine kinase 0.2282 0.609 0.6089
Loa Loa (eye worm) TK/RYK protein kinase 0.1301 0.3464 0.3462
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0006 0.0006
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0229 0.0592 0.0589
Loa Loa (eye worm) hypothetical protein 0.0039 0.0084 0.008
Echinococcus granulosus glutathione S transferase 0.0032 0.0064 0.0063
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0021 0.0036 0.0046
Onchocerca volvulus 0.0021 0.0036 0.0052
Loa Loa (eye worm) hypothetical protein 0.0118 0.0296 0.0292
Plasmodium vivax tyrosine kinase-like protein, putative 0.1301 0.3464 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1301 0.3464 0.5686
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0981 0.2605 0.2604
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Loa Loa (eye worm) STAT protein 0.0981 0.2605 0.2603
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Brugia malayi SRC-1 0.2303 0.6146 0.8042
Schistosoma mansoni aldo-keto reductase 0.0031 0.0063 0.0083
Echinococcus granulosus tyrosine protein kinase pr2 0.1301 0.3464 0.3464
Brugia malayi RhoGAP domain containing protein 0.0981 0.2605 0.3407
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1301 0.3464 0.3464
Entamoeba histolytica hypothetical protein 0.0021 0.0036 0.0052
Schistosoma mansoni elongation factor 1-gamma 0.0016 0.0024 0.003
Schistosoma mansoni cpg binding protein 0.003 0.0059 0.0079
Loa Loa (eye worm) TK protein kinase 0.1301 0.3464 0.3462
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0104 0.0288
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Brugia malayi Protein kinase domain containing protein 0.1301 0.3464 0.4531
Loa Loa (eye worm) hypothetical protein 0.0981 0.2605 0.2603
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.0317 0.0906
Echinococcus granulosus nuclear receptor nhr 48 0.0018 0.0029 0.0028
Brugia malayi SH2 domain containing protein 0.2282 0.609 0.7969
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Schistosoma mansoni single-minded 0.0048 0.0107 0.0143
Echinococcus multilocularis geminin 0.0559 0.1477 0.1476
Echinococcus granulosus tyrosine protein kinase 0.1301 0.3464 0.3464
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0032
Schistosoma mansoni hypothetical protein 0.0981 0.2605 0.3532
Entamoeba histolytica protein kinase, putative 0.1301 0.3464 0.5686
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0035 0.009
Brugia malayi Nuclear hormone receptor E75 0.0018 0.0029 0.0033
Plasmodium falciparum elongation factor 1-gamma, putative 0.0016 0.0024 0.0057
Brugia malayi hydrolase, alpha/beta fold family protein 0.0037 0.0079 0.0098
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.0031
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0042 0.1185
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0981 0.2605 0.2604
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0074 0.0073
Echinococcus multilocularis retinal guanylyl cyclase 2 0.1301 0.3464 0.3464
Schistosoma mansoni intermediate filament proteins 0.0026 0.005 0.0067
Loa Loa (eye worm) TK/CSK protein kinase 0.1301 0.3464 0.3462
Trichomonas vaginalis TKL family protein kinase 0.1301 0.3464 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0049 0.0045
Entamoeba histolytica aldose reductase, putative 0.0031 0.0063 0.0097
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0063 0.017
Schistosoma mansoni hypothetical protein 0.04 0.105 0.1423
Brugia malayi SH2 domain containing protein 0.0981 0.2605 0.3407
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.1301 0.3464 0.5686
Entamoeba histolytica hypothetical protein 0.0021 0.0036 0.0052
Echinococcus multilocularis neuropeptide s receptor 0.0454 0.1194 0.1193
Trichomonas vaginalis conserved hypothetical protein 0.1301 0.3464 1
Schistosoma mansoni tyrosine kinase 0.1301 0.3464 0.4697
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0981 0.2605 0.2604
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0031 0.0063 0.0061
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Echinococcus multilocularis tyrosine protein kinase ABL1 0.3743 1 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.1301 0.3464 0.3464
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0039 0.0084 0.0083
Echinococcus granulosus intermediate filament protein 0.0026 0.005 0.0049
Entamoeba histolytica hypothetical protein 0.1301 0.3464 0.5686
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0022
Schistosoma mansoni potassium channel beta 0.0009 0.0004 0.0003
Echinococcus multilocularis natriuretic peptide receptor 1 0.1301 0.3464 0.3464
Brugia malayi Tyrosine-protein kinase abl-1 0.0902 0.2395 0.3131
Plasmodium vivax protein kinase, putative 0.1301 0.3464 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0039 0.0084 0.008
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.001 0.0006 0.0006
Echinococcus granulosus aldehyde reductase 0.0022 0.0039 0.0037
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0091 0.0253
Echinococcus granulosus aldo keto reductase 0.0031 0.0063 0.0061
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0021 0.002
Brugia malayi Guanylyl cyclase protein 23 0.1301 0.3464 0.4531
Schistosoma mansoni hypothetical protein 0.0559 0.1477 0.2001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0023 0.0055
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0981 0.2605 0.3532
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0286 0.0745 0.2141
Echinococcus granulosus c src tyrosine kinase 0.2303 0.6146 0.6145
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0035 0.009
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0091 0.0253
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0039 0.0084 0.0105
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0034 0.0071 0.011
Entamoeba histolytica protein kinase domain containing protein 0.1301 0.3464 0.5686
Trypanosoma brucei elongation factor 1 gamma, putative 0.0016 0.0024 0.0057
Echinococcus granulosus lamin dm0 0.0026 0.005 0.0049
Echinococcus multilocularis protein kinase 0.1301 0.3464 0.3464

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 3.42 nM In vitro antimalarial activity against HB3 chloroquine sensitive strain of Plasmodium falciparum (HB3 strain) ChEMBL. 11141088
IC50 (functional) = 4.62 nM In vitro antimalarial activity against K1 chloroquine resistant strain of Plasmodium falciparum (K1 strain) ChEMBL. 11141088

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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