Detailed information for compound 289345

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 287.13 | Formula: C10H7BrO3S
  • H donors: 0 H acceptors: 3 LogP: 2.09 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1C(=C(C)S(=O)(=O)c2c1cccc2)Br
  • InChi: 1S/C10H7BrO3S/c1-6-9(11)10(12)7-4-2-3-5-8(7)15(6,13)14/h2-5H,1H3
  • InChiKey: BTYUJLVBXZSAHY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0016 0.0019 0.005
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0111 0.061 0.0877
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0121 0.0671 0.2808
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0395 0.2376 0.8613
Trypanosoma cruzi PAB1-binding protein , putative 0.0099 0.0534 0.0713
Entamoeba histolytica cysteine protease, putative 0.0121 0.0671 0.2808
Onchocerca volvulus 0.0395 0.2376 1
Echinococcus multilocularis histone deacetylase 6 0.0074 0.0378 0.0373
Entamoeba histolytica cysteine proteinase, putative 0.0395 0.2376 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0037 0.0044
Toxoplasma gondii histone deacetylase HDAC4 0.0047 0.0208 0.0739
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0057 0.0188
Echinococcus granulosus histone deacetylase 8 0.0047 0.0208 0.0274
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0037 0.0138
Onchocerca volvulus 0.008 0.0418 0.1741
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0395 0.2376 0.8616
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0044 0.0193 0.0254
Echinococcus multilocularis histone deacetylase 3 0.0091 0.0482 0.0478
Echinococcus granulosus pyruvate kinase 0.0017 0.0022 0.0023
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0055 0.0258 0.107
Mycobacterium tuberculosis Conserved protein 0.0111 0.061 0.0877
Plasmodium falciparum pyruvate kinase 0.0033 0.0122 0.0492
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0165 0.0943 0.1266
Leishmania major DNA polymerase kappa, putative 0.0019 0.0037 0.0119
Loa Loa (eye worm) hypothetical protein 0.0047 0.0209 0.0275
Mycobacterium tuberculosis Conserved hypothetical protein 0.0084 0.0437 0.0622
Trypanosoma cruzi cysteine peptidase, putative 0.0395 0.2376 0.3198
Onchocerca volvulus 0.0061 0.0298 0.1235
Plasmodium vivax histone deacetylase, putative 0.0047 0.0208 0.0858
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0064 0.0217
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0135 0.013
Plasmodium vivax vivapain-2 0.0395 0.2376 1
Schistosoma mansoni voltage-gated potassium channel 0.009 0.0479 0.0639
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.001 0.002
Onchocerca volvulus 0.0395 0.2376 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0395 0.2376 0.8616
Echinococcus multilocularis smad 0.0017 0.002 0.0016
Echinococcus multilocularis protoporphyrinogen oxidase 0.0084 0.0437 0.0433
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0064 0.0217
Echinococcus granulosus Solute carrier organic anion transporter family 0.008 0.0418 0.0557
Plasmodium falciparum protoporphyrinogen oxidase 0.0084 0.0437 0.1823
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0056 0.0266 0.0352
Trichomonas vaginalis ap endonuclease, putative 0.0055 0.0258 0.0921
Schistosoma mansoni ap endonuclease 0.0055 0.0258 0.0342
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0135 0.0472
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.001 0.002
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0122 0.0424
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0482 0.1734
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0061 0.0076
Plasmodium vivax unspecified product 0.0044 0.0189 0.0778
Schistosoma mansoni cathepsin F (C01 family) 0.0351 0.2103 0.2831
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0014 0.0005 0.0018
Toxoplasma gondii preprocathepsin c precursor, putative 0.0121 0.0671 0.2419
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.002 0.0021
Echinococcus multilocularis histone deacetylase 6 0.0074 0.0378 0.0373
Schistosoma mansoni cathepsin B (C01 family) 0.0121 0.0671 0.0898
Schistosoma mansoni inositol monophosphatase 0.0036 0.0143 0.0186
Brugia malayi Papain family cysteine protease containing protein 0.0165 0.0943 0.1266
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0084 0.0437 0.1823
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0015 0.001 0.002
Schistosoma mansoni hypothetical protein 0.0295 0.1754 0.236
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0165 0.0943 0.3409
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0015 0.001 0.0008
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0015 0.001 0.0024
Onchocerca volvulus Matrilysin homolog 0.0096 0.0513 0.2141
Onchocerca volvulus Putative organic anion transporter 0.008 0.0418 0.1741
Loa Loa (eye worm) hypothetical protein 0.008 0.0418 0.0557
Loa Loa (eye worm) hypothetical protein 0.0111 0.061 0.0816
Chlamydia trachomatis hexose phosphate transporter 0.0024 0.0064 0.1149
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0061 0.0062
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0016 0.0019 0.0018
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0016 0.0019 0.0018
Leishmania major cathepsin L-like protease 0.0395 0.2376 0.8613
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0135 0.0472
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0395 0.2376 0.8613
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1186 0.7306 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0789 0.1058
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0027
Toxoplasma gondii prolyl endopeptidase 0.0135 0.0757 0.2732
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0038 0.0153 0.0199
Loa Loa (eye worm) hypothetical protein 0.0048 0.0218 0.0288
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0482 0.1734
Loa Loa (eye worm) histone deacetylase 11 0.0047 0.0208 0.0274
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0019 0.0018
Mycobacterium ulcerans lipase LipD 0.0111 0.061 0.0814
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0077 0.0098
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0209 0.0861
Entamoeba histolytica cysteine protease, putative 0.0395 0.2376 1
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0122 0.0145
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0016 0.0015
Brugia malayi hypothetical protein 0.008 0.0418 0.0557
Loa Loa (eye worm) inositol-1 0.0036 0.0143 0.0186
Brugia malayi Importin beta-1 subunit 0.0031 0.0107 0.0138
Schistosoma mansoni hypothetical protein 0.0684 0.4181 0.5634
Brugia malayi Metabotropic glutamate receptor precursor. 0.0042 0.0177 0.0232
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.061 0.2197
Brugia malayi Cathepsin L-like cysteine proteinase 0.0351 0.2103 0.2831
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0121 0.0671 0.2808
Leishmania major histone deacetylase, putative 0.0091 0.0482 0.1734
Loa Loa (eye worm) hypothetical protein 0.0084 0.0437 0.0583
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0395 0.2376 0.3198
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0015 0.001 0.0008
Brugia malayi cathepsin F-like cysteine proteinase 0.0044 0.0189 0.0249
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0055 0.0259 0.0923
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0016 0.0041
Brugia malayi Cathepsin L-like precursor 0.0395 0.2376 0.3198
Echinococcus granulosus integrin beta 2 0.0261 0.1544 0.2076
Brugia malayi prostaglandin transporter 0.008 0.0418 0.0557
Trypanosoma cruzi cysteine peptidase, putative 0.0044 0.0189 0.0249
Loa Loa (eye worm) hypothetical protein 0.008 0.0418 0.0557
Giardia lamblia Cathepsin L precursor 0.0121 0.0671 0.2419
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0395 0.2376 0.8613
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0015 0.001 0.0038
Loa Loa (eye worm) CYP4Cod1 0.0026 0.0077 0.0098
Loa Loa (eye worm) hypothetical protein 0.0031 0.0107 0.0138
Loa Loa (eye worm) hypothetical protein 0.0027 0.0086 0.011
Echinococcus multilocularis cathepsin b 0.1204 0.7418 0.7417
Mycobacterium ulcerans oxidoreductase 0.0084 0.0437 0.0578
Loa Loa (eye worm) hypothetical protein 0.008 0.0418 0.0557
Plasmodium vivax hypothetical protein, conserved 0.0111 0.061 0.2551
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0121 0.0669 0.0964
Schistosoma mansoni hypothetical protein 0.0326 0.1947 0.2619
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0204 0.0268
Schistosoma mansoni cpg binding protein 0.0022 0.0053 0.0065
Schistosoma mansoni hypothetical protein 0.0684 0.4181 0.5634
Loa Loa (eye worm) hypothetical protein 0.0135 0.0757 0.1014
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0143 0.0186
Entamoeba histolytica cysteine proteinase, putative 0.0395 0.2376 1
Brugia malayi glutathione reductase 0.0046 0.0204 0.0268
Onchocerca volvulus 0.008 0.0418 0.1741
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0054 0.0251 0.0347
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0789 0.1058
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0037 0.0136
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0395 0.2376 0.8613
Brugia malayi hypothetical protein 0.0064 0.0315 0.0418
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0121 0.0671 0.2419
Trypanosoma cruzi cruzipain precursor, putative 0.0395 0.2376 0.3198
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0015 0.001 0.0008
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0061 0.0238
Schistosoma mansoni voltage-gated potassium channel 0.009 0.0479 0.0639
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0157 0.0893 0.1199
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0061 0.0076
Loa Loa (eye worm) integrin beta-2 0.0357 0.2139 0.2879
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0395 0.2376 1
Echinococcus multilocularis Smad4 0.0017 0.002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0111 0.061 0.0816
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0057 0.0219
Echinococcus granulosus voltage gated potassium channel 0.0024 0.0066 0.0082
Loa Loa (eye worm) hypothetical protein 0.0024 0.0066 0.0082
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0054 0.0251 0.0322
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.09 0.0895
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0071 0.0089
Brugia malayi Cathepsin L-like precursor 0.0351 0.2103 0.2831
Echinococcus granulosus pyruvate kinase 0.0033 0.0122 0.0157
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0037 0.0136
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0015 0.001 0.002
Mycobacterium ulcerans beta-lactamase 0.0111 0.061 0.0814
Echinococcus granulosus GPCR family 2 0.0047 0.0209 0.0275
Trichomonas vaginalis transport proetin, putative 0.0024 0.0064 0.0217
Schistosoma mansoni histone deacetylase hda2 0.0047 0.0208 0.0274
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.0036
Schistosoma mansoni alpha-glucosidase 0.0136 0.0763 0.1023
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0015 0.001 0.0024
Onchocerca volvulus Cathepsin L homolog 0.0395 0.2376 1
Entamoeba histolytica cysteine proteinase, putative 0.0165 0.0943 0.3958
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.061 0.2197
Loa Loa (eye worm) hypothetical protein 0.0121 0.0671 0.0898
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0084 0.0437 0.0578
Giardia lamblia Pyruvate kinase 0.0017 0.0022 0.0062
Brugia malayi beta-lactamase family protein 0.0111 0.061 0.0816
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0025 0.0204
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0037 0.0119
Plasmodium falciparum histone deacetylase 1 0.0091 0.0482 0.2013
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0209 0.0275
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0015 0.001 0.002
Giardia lamblia Cysteine protease 0.0121 0.0671 0.2419
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.006 0.0231
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0026 0.0077 0.0084
Trypanosoma cruzi cysteine peptidase, putative 0.0395 0.2376 0.3198
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0071 0.024
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0015 0.001 0.0008
Brugia malayi Calcitonin receptor-like protein seb-1 0.0148 0.084 0.1127
Trypanosoma cruzi histone deacetylase, putative 0.0047 0.0208 0.0274
Leishmania major hypothetical protein, conserved 0.0099 0.0534 0.1921
Schistosoma mansoni hypothetical protein 0.0047 0.0209 0.0275
Loa Loa (eye worm) hypothetical protein 0.0047 0.0208 0.0274
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0122 0.0156
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0015 0.001 0.002
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1204 0.7418 1
Onchocerca volvulus Putative organic anion transporter 0.008 0.0418 0.1741
Loa Loa (eye worm) histone deacetylase 0.0074 0.0378 0.0503
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0053 0.0244 0.0322
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0395 0.2376 0.8616
Schistosoma mansoni cathepsin C 0.0121 0.0671 0.0898
Entamoeba histolytica cysteine protease, putative 0.0165 0.0943 0.3958
Onchocerca volvulus 0.0395 0.2376 1
Trypanosoma brucei cysteine peptidase C (CPC) 0.0456 0.2757 1
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0091 0.0482 0.1734
Entamoeba histolytica cysteine protease, putative 0.0165 0.0943 0.3958
Brugia malayi Cathepsin L-like precursor 0.0395 0.2376 0.3198
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0395 0.2376 0.8613
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0218 0.0288
Plasmodium falciparum serine repeat antigen 8 0.0121 0.0671 0.2808
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0119 0.0152
Trypanosoma brucei prolyl oligopeptidase, putative 0.0054 0.0251 0.0909
Giardia lamblia Cysteine protease 0.0121 0.0671 0.2419
Loa Loa (eye worm) hypothetical protein 0.0023 0.0061 0.0076
Trichomonas vaginalis ap endonuclease, putative 0.0055 0.0258 0.0921
Echinococcus multilocularis voltage gated potassium channel 0.0024 0.0066 0.0061
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0395 0.2376 0.8613
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0135 0.0472
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0016 0.0041
Leishmania major histone deacetylase, putative 0.0091 0.0482 0.1734
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0165 0.0943 0.1266
Giardia lamblia Cysteine protease 0.0121 0.0671 0.2419
Loa Loa (eye worm) glutamate receptor 0.0042 0.0177 0.0232
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0025 0.0013
Echinococcus granulosus cathepsin L 0.0121 0.0671 0.0898
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.001 0.002
Trypanosoma cruzi oligopeptidase b 0.0054 0.0251 0.0332
Brugia malayi Matrixin family protein 0.0043 0.0185 0.0244
Plasmodium vivax hypothetical protein, conserved 0.0084 0.0437 0.1823
Entamoeba histolytica cysteine protease, putative 0.0165 0.0943 0.3958
Plasmodium vivax ataxin-2 like protein, putative 0.0099 0.0534 0.223
Trypanosoma brucei histone deacetylase 1 0.0091 0.0482 0.1748
Plasmodium vivax hypothetical protein, conserved 0.0084 0.0437 0.1823
Brugia malayi Histone deacetylase family protein 0.0074 0.0378 0.0503
Loa Loa (eye worm) hypothetical protein 0.0044 0.0189 0.0249
Echinococcus multilocularis cathepsin L 0.0121 0.0671 0.0666
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0122 0.0157
Brugia malayi Matrixin family protein 0.0043 0.0185 0.0244
Onchocerca volvulus 0.0395 0.2376 1
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0037 0.0044
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0057 0.007
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0022 0.0072
Giardia lamblia Cathepsin B precursor 0.0456 0.2757 1
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0015 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0027
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0025 0.0084
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0291 0.1038
Leishmania major cathepsin L-like protease 0.0395 0.2376 0.8613
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.061 0.0816
Brugia malayi MH2 domain containing protein 0.0244 0.1438 0.1933
Mycobacterium tuberculosis Probable lipase LipE 0.0111 0.061 0.0877
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0121 0.0671 0.2808
Brugia malayi histone deacetylase 1 (HD1) 0.0091 0.0482 0.0644
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0016 0.0041
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.002 0.0016
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0057 0.007
Echinococcus multilocularis integrin beta 2 0.0261 0.1544 0.154
Echinococcus granulosus organic anion transporting polypeptide 30B 0.008 0.0418 0.0557
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0121 0.0671 0.2808
Loa Loa (eye worm) hypothetical protein 0.0044 0.0189 0.0249
Echinococcus granulosus hyperpolarization activated cyclic 0.0016 0.0019 0.0018
Trypanosoma brucei cytochrome P450, putative 0.0026 0.0077 0.0281
Loa Loa (eye worm) beta-lactamase 0.0111 0.061 0.0816
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0054 0.0251 0.0894
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1204 0.7418 1
Brugia malayi Matrixin family protein 0.0043 0.0185 0.0244
Mycobacterium tuberculosis Conserved protein 0.0111 0.061 0.0877
Loa Loa (eye worm) hypothetical protein 0.0043 0.0185 0.0244
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0016 0.0058
Loa Loa (eye worm) hypothetical protein 0.0055 0.0259 0.0343
Loa Loa (eye worm) hypothetical protein 0.0051 0.0237 0.0313
Giardia lamblia Cathepsin B precursor 0.0121 0.0671 0.2419
Schistosoma mansoni metabotropic glutamate receptor 0.0035 0.0135 0.0175
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.002 0.0021
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0054 0.0251 0.0332
Echinococcus multilocularis pyruvate kinase 0.0033 0.0122 0.0117
Giardia lamblia Cathepsin B precursor 0.0121 0.0671 0.2419
Trypanosoma brucei histone deacetylase 4 0.0074 0.0378 0.137
Schistosoma mansoni cathepsin S (C01 family) 0.0121 0.0671 0.0898
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0084 0.0437 0.1823
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0024 0.0066 0.0061
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0055 0.0258 0.0921
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0016 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0064 0.0217
Trypanosoma cruzi histone deacetylase, putative 0.0074 0.0378 0.0503
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0789 0.0785
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0037 0.0044
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0016 0.0058
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0083 0.0431 0.0575
Leishmania major UDP-galactopyranose mutase 0.0084 0.0437 0.1571
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0122 0.0157
Brugia malayi Integrin beta pat-3 precursor 0.0357 0.2139 0.2879
Loa Loa (eye worm) cysteine protease 0.0395 0.2376 0.3198
Toxoplasma gondii thioredoxin reductase 0.0046 0.0204 0.0722
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0055 0.0258 0.107
Entamoeba histolytica cysteine protease, putative 0.0165 0.0943 0.3958
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0395 0.2376 0.8616
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0135 0.0472
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0135 0.0757 0.2732
Mycobacterium ulcerans hydrolase 0.0053 0.0244 0.0312
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0121 0.0671 0.2808
Loa Loa (eye worm) hypothetical protein 0.0072 0.0363 0.0484
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0061 0.0205
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0015 0.001 0.0008
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0016 0.0048
Plasmodium vivax histone deacetylase 1, putative 0.0091 0.0482 0.2013
Brugia malayi sodium-independent organic anion transporter family protein 0.008 0.0418 0.0557
Loa Loa (eye worm) hypothetical protein 0.0023 0.006 0.0074
Brugia malayi SPARC precursor 0.0055 0.0259 0.0343
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0016 0.0019 0.0018
Brugia malayi beta-lactamase family protein 0.0111 0.061 0.0816
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0051 0.0237 0.0232
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0037 0.0136
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0025 0.0084
Plasmodium falciparum serine repeat antigen 9 0.0121 0.0671 0.2808
Trypanosoma brucei histone deacetylase 3 0.0074 0.0378 0.137
Echinococcus granulosus cathepsin L 0.0165 0.0943 0.1266
Plasmodium falciparum ataxin-2 like protein, putative 0.0099 0.0534 0.223
Echinococcus granulosus metabotropic glutamate receptor 5 0.0051 0.0237 0.0313
Echinococcus granulosus pyruvate kinase 0.0017 0.0022 0.0023
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0055 0.0259 0.0343
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0083 0.0431 0.0427
Brugia malayi cathepsin B-like cysteine proteinase 0.1204 0.7418 1
Entamoeba histolytica cysteine protease, putative 0.0121 0.0671 0.2808
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0121 0.0671 0.2419
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0019 0.0018
Brugia malayi Cytochrome P450 family protein 0.0026 0.0077 0.0098
Mycobacterium leprae PROBABLE HYDROLASE 0.0053 0.0244 0.3135
Toxoplasma gondii histone lysine-specific demethylase 0.0084 0.0437 0.1571
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.001 0.002
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0024 0.0066 0.0082
Echinococcus granulosus dnaJ subfamily B 0.0295 0.1754 0.236
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0037 0.0119
Echinococcus granulosus pyruvate kinase 0.0033 0.0122 0.0157
Loa Loa (eye worm) hypothetical protein 0.0053 0.0249 0.033
Brugia malayi cathepsin L-like precursor 0.0351 0.2103 0.2831
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0291 0.0405
Echinococcus multilocularis geminin 0.0684 0.4181 0.4179
Brugia malayi mbt repeat family protein 0.0047 0.0209 0.0275
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0122 0.0441
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0015 0.001 0.0006
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0057 0.007
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0119 0.0997
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0084 0.0437 0.0583
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0121 0.0671 0.0898
Entamoeba histolytica cysteine proteinase 2 0.0165 0.0943 0.3958
Onchocerca volvulus 0.0043 0.0185 0.0761
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0122 0.0492
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0456 0.2757 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0061 0.0062
Entamoeba histolytica cysteine protease, putative 0.0121 0.0671 0.2808
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0015 0.001 0.0008
Schistosoma mansoni ran 0.0022 0.0057 0.007
Echinococcus multilocularis cysteine protease 0.0395 0.2376 0.2372
Plasmodium falciparum importin beta, putative 0.0031 0.0107 0.043
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0395 0.2376 0.2372
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0121 0.0671 0.0898
Leishmania major DNA polymerase eta, putative 0.0019 0.0037 0.0119
Trypanosoma cruzi histone deacetylase 1, putative 0.0091 0.0482 0.0644
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0789 0.1058
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0209 0.0275
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0209 0.0275
Brugia malayi cathepsin L precursor 0.0121 0.0671 0.0898
Chlamydia trachomatis protoporphyrinogen oxidase 0.0084 0.0437 1
Loa Loa (eye worm) glutamate receptor 0.0016 0.0019 0.0019
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0121 0.0671 0.0898
Loa Loa (eye worm) hypothetical protein 0.0121 0.0671 0.0898
Schistosoma mansoni ran 0.0022 0.0057 0.007
Trypanosoma brucei histone deacetylase, putative 0.0074 0.0378 0.137
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0016 0.0015
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0016 0.0058
Toxoplasma gondii histone lysine methyltransferase SET1 0.0039 0.0161 0.0568
Toxoplasma gondii exonuclease III APE 0.0055 0.0258 0.0921
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0122 0.0441
Giardia lamblia Cathepsin L precursor 0.0121 0.0671 0.2419
Onchocerca volvulus Cathepsin L homolog 0.0395 0.2376 1
Echinococcus multilocularis expressed protein 0.0055 0.0259 0.0254
Echinococcus granulosus snurportin 1 0.0326 0.1947 0.2619
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.061 0.2197
Brugia malayi Papain family cysteine protease containing protein 0.0395 0.2376 0.3198
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.2103 0.7623
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0135 0.0472
Echinococcus multilocularis prolyl endopeptidase 0.0135 0.0757 0.0752
Echinococcus granulosus cathepsin b 0.1204 0.7418 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0061 0.0238
Trypanosoma cruzi cruzipain precursor, putative 0.0044 0.0189 0.0249
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0291 0.0286
Loa Loa (eye worm) matrix metalloproteinase 0.0043 0.0185 0.0244
Onchocerca volvulus 0.008 0.0418 0.1741
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.006 0.0074
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0121 0.0671 0.2419
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0121 0.0671 0.2419
Schistosoma mansoni agrin 0.0055 0.0259 0.0343
Entamoeba histolytica cysteine proteinase, putative 0.0165 0.0943 0.3958
Onchocerca volvulus Histone deacetylase 10 homolog 0.0047 0.0208 0.0858
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0165 0.0943 0.1266
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0121 0.0671 0.2419
Entamoeba histolytica cysteine proteinase 1, putative 0.0165 0.0943 0.3958
Toxoplasma gondii cathepsin CPC2 0.0121 0.0671 0.2419
Plasmodium falciparum serine repeat antigen 4 0.0121 0.0671 0.2808
Mycobacterium leprae conserved hypothetical protein 0.0111 0.061 0.941
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0135 0.0472
Loa Loa (eye worm) hypothetical protein 0.0019 0.0037 0.0044
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0055 0.0258 0.107
Schistosoma mansoni smad 0.0017 0.002 0.0021
Mycobacterium tuberculosis Probable lipase LipD 0.0111 0.061 0.0877
Echinococcus multilocularis histone deacetylase 8 0.0047 0.0208 0.0203
Trypanosoma cruzi major cysteine proteinase, putative 0.0121 0.0671 0.0898
Loa Loa (eye worm) CXXC zinc finger family protein 0.0021 0.0046 0.0055
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0024 0.0064 0.0071
Schistosoma mansoni hypothetical protein 0.0047 0.0209 0.0275
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0482 0.1734
Echinococcus granulosus beta LACTamase domain containing family member 0.0111 0.061 0.0816
Leishmania major cathepsin L-like protease 0.0395 0.2376 0.8613
Echinococcus multilocularis dnaJ subfamily B 0.0295 0.1754 0.175
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0044 0.019 0.025
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0121 0.0671 0.2419
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1204 0.7418 1
Loa Loa (eye worm) hypothetical protein 0.0111 0.061 0.0816
Onchocerca volvulus 0.0055 0.0259 0.1071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0121 0.0671 0.2419
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0055 0.0259 0.0923
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0291 0.0385
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.061 0.0816
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0055 0.0258 0.0921
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0143 0.0502
Trypanosoma cruzi major cysteine proteinase, putative 0.0121 0.0671 0.0898
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0015 0.001 0.0006
Onchocerca volvulus Cathepsin L homolog 0.0121 0.0671 0.2808
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0121 0.0671 0.2808
Schistosoma mansoni metabotropic glutamate receptor 0.002 0.0044 0.0052
Mycobacterium tuberculosis Conserved protein 0.0111 0.061 0.0877
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0291 0.1038
Echinococcus multilocularis agrin 0.0055 0.0259 0.0254
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0482 0.1734
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0016 0.0015
Brugia malayi Smad1 0.0017 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0084 0.0437 0.0583
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0018
Giardia lamblia Cysteine protease 0.0121 0.0671 0.2419
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0019 0.0004
Brugia malayi secreted modular calcium-binding protein 1 0.0055 0.0259 0.0343
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0249 0.033
Giardia lamblia Encystation-specific protease 0.0121 0.0671 0.2419
Schistosoma mansoni cpg binding protein 0.0021 0.0046 0.0055
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0165 0.0943 0.1266
Entamoeba histolytica cysteine protease, putative 0.0165 0.0943 0.3958
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0135 0.0472
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0121 0.0671 0.2419
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0291 0.0385
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0121 0.0671 0.2808
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0209 0.0275
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.002 0.0016
Schistosoma mansoni cathepsin s 0.0044 0.0189 0.0249
Schistosoma mansoni histone deacetylase 1 2 3 0.0047 0.0208 0.0274
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0016 0.0019 0.0018
Trypanosoma cruzi histone deacetylase, putative 0.0074 0.0378 0.0503
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0209 0.0275
Echinococcus multilocularis pyruvate kinase 0.0017 0.0022 0.0017
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0117 0.0644 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0143 0.0583
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0015 0.001 0.0008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0121 0.0671 0.0898
Echinococcus granulosus follistatin 0.0055 0.0259 0.0343
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0077 0.0397 0.1426
Brugia malayi Histone deacetylase 1 0.0091 0.0482 0.0644
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0019 0.0018
Leishmania major cathepsin L-like protease 0.0395 0.2376 0.8613
Giardia lamblia Cathepsin B precursor 0.0456 0.2757 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0395 0.2376 0.8613
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0016 0.0019 0.0018
Echinococcus multilocularis histone deacetylase 0.0074 0.0378 0.0373
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0015 0.001 0.0008
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0016 0.0041
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0037 0.0044
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0122 0.0157
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0053 0.0244 0.0336
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0121 0.0671 0.0898
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0084 0.0437 0.0433
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0209 0.0275
Echinococcus multilocularis cysteine protease 0.0395 0.2376 0.2372
Giardia lamblia Hypothetical protein 0.0121 0.0671 0.2419
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0091 0.0482 0.1734
Trichomonas vaginalis glucarate, hexuronate transporter, putative 0.0024 0.0064 0.0217
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0117 0.0644 0.0927
Loa Loa (eye worm) hypothetical protein 0.0043 0.0185 0.0244
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0019 0.0004
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0015 0.001 0.0008
Echinococcus granulosus cysteine protease 0.0165 0.0943 0.1266
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0121 0.0671 0.2419
Loa Loa (eye worm) hypothetical protein 0.0044 0.0189 0.0249
Giardia lamblia Sugar transport family protein 0.0024 0.0064 0.0217
Loa Loa (eye worm) hypothetical protein 0.008 0.0418 0.0557
Entamoeba histolytica cysteine protease, putative 0.0165 0.0943 0.3958
Loa Loa (eye worm) histone deacetylase 3 0.0091 0.0482 0.0644
Giardia lamblia Cathepsin L-like protease 0.0121 0.0671 0.2419
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0209 0.0204
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0135 0.0757 0.1014
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0061 0.0238
Echinococcus multilocularis cathepsin b 0.1204 0.7418 0.7417
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0016 0.0019 0.0014
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0121 0.0671 0.0898
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0204 0.0199
Echinococcus granulosus agrin 0.0055 0.0259 0.0343
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0107 0.0388
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0057 0.0052
Toxoplasma gondii cathepsin B 0.0456 0.2757 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0121 0.0671 0.2419
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.014 0.0789 0.1058
Loa Loa (eye worm) hypothetical protein 0.0111 0.061 0.0816
Plasmodium falciparum thioredoxin reductase 0.0046 0.0204 0.0838
Echinococcus multilocularis tumor protein p63 0.0331 0.1976 0.1972
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.061 0.2197
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.008 0.0418 0.0413
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0111 0.061 0.0877
Leishmania major histone deacetylase, putative 0.0074 0.0378 0.1355
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0291 0.0385
Loa Loa (eye worm) Smad1 0.0017 0.002 0.0021
Brugia malayi mbt repeat family protein 0.0047 0.0209 0.0275
Echinococcus multilocularis histone deacetylase 7 0.0074 0.0378 0.0373
Plasmodium vivax vivapain-2 0.0395 0.2376 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0055 0.0258 0.0937
Schistosoma mansoni follistatin 0.0055 0.0259 0.0343
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0395 0.2376 0.8616
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0135 0.0175
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0204 0.0838
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0016 0.0015
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0061 0.0067
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0121 0.0671 0.0898
Trypanosoma cruzi PAB1-binding protein , putative 0.0099 0.0534 0.0713
Loa Loa (eye worm) matrixin family protein 0.0096 0.0513 0.0685
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0016 0.0019 0.0018
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0016 0.0019 0.0014
Loa Loa (eye worm) hypothetical protein 0.0055 0.0259 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0121 0.0671 0.2419
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0121 0.0671 0.0898
Echinococcus granulosus histone deacetylase 6 0.0074 0.0378 0.0503
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0395 0.2376 0.2372
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0014 0.0005 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0037 0.0136
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0055 0.0258 0.0254
Leishmania major importin beta-1 subunit, putative 0.0025 0.0071 0.024
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0209 0.0275
Schistosoma mansoni histone deacetylase 4 5 0.0074 0.0378 0.0503
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0016 0.0015
Echinococcus granulosus metabotropic glutamate receptor 2 0.0035 0.0135 0.0175
Brugia malayi Papain family cysteine protease containing protein 0.0121 0.0671 0.0898
Schistosoma mansoni smad1 5 8 and 0.0017 0.002 0.0021
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0121 0.0671 0.0898
Leishmania major cysteine peptidase A (CPA) 0.0395 0.2376 0.8613
Schistosoma mansoni inositol monophosphatase 0.0036 0.0143 0.0186
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0037 0.0029
Entamoeba histolytica cysteine protease, putative 0.0121 0.0671 0.2808
Onchocerca volvulus 0.0111 0.061 0.2551
Trypanosoma cruzi UDP-galactopyranose mutase 0.0084 0.0437 0.0583
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0015 0.001 0.0024
Trypanosoma brucei histone deacetylase 2 0.0047 0.0208 0.0755
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0044 0.0189 0.0249
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0571 0.082
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0143 0.0138
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.09 0.0895
Leishmania major trypanothione reductase 0.0046 0.0204 0.0722
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0016 0.0019 0.0018
Brugia malayi cathepsin L-like cysteine proteinase 0.0121 0.0671 0.0898
Echinococcus multilocularis histone deacetylase 1 0.0091 0.0482 0.0478
Brugia malayi MH1 domain containing protein 0.0017 0.002 0.0021
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0016 0.0015
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0395 0.2376 1
Entamoeba histolytica cysteine proteinase, putative 0.0165 0.0943 0.3958
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0077 0.0098
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0037 0.0136
Giardia lamblia Cathepsin L precursor 0.0121 0.0671 0.2419
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0016 0.0041
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0037 0.0032
Loa Loa (eye worm) sodium-independent organic anion transporter 0.008 0.0418 0.0557
Trichomonas vaginalis ran, putative 0.0022 0.0057 0.0188
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0249 0.033
Brugia malayi Papain family cysteine protease containing protein 0.0121 0.0671 0.0898
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0395 0.2376 0.8613
Plasmodium falciparum serine repeat antigen 7 0.0121 0.0671 0.2808
Giardia lamblia Pyruvate kinase 0.0033 0.0122 0.0424
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0037 0.0044
Trypanosoma brucei hypothetical protein, conserved 0.0111 0.061 0.2211
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0015 0.001 0.0024
Loa Loa (eye worm) POT family protein 0.004 0.0167 0.0218
Schistosoma mansoni alpha-glucosidase 0.0136 0.0763 0.1023
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.014 0.0789 0.1058
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0121 0.0671 0.0898
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0016 0.0041
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0019 0.0004
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0027
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0037 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0037 0.0136
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0204 0.0268
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0055 0.0258 0.0342
Trypanosoma cruzi cysteine peptidase, putative 0.0395 0.2376 0.3198
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.09 0.1207
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0037 0.0044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0016 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0395 0.2376 0.8613
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0037 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0121 0.0671 0.2419
Echinococcus granulosus lysine specific histone demethylase 1A 0.0084 0.0437 0.0583
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0037 0.0136
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0015 0.001 0.0008
Echinococcus granulosus Smad4 0.0017 0.002 0.0021
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0037 0.0032
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0027
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0061 0.0205
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.09 0.1207
Echinococcus multilocularis beta LACTamase domain containing family member 0.0111 0.061 0.0605
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0204 0.0277
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0015 0.001 0.0008
Entamoeba histolytica cysteine protease, putative 0.0165 0.0943 0.3958
Entamoeba histolytica cysteine protease, putative 0.0121 0.0671 0.2808
Plasmodium vivax importin-beta 2, putative 0.0031 0.0107 0.043
Chlamydia trachomatis pyruvate kinase 0.0033 0.0122 0.2505
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0035 0.0135 0.013
Brugia malayi hypothetical protein 0.0024 0.0064 0.008
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0249 0.0245
Entamoeba histolytica cysteine protease, putative 0.0165 0.0943 0.3958
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0016 0.0048
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0135 0.0175
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0024 0.0066 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0395 0.2376 0.8613
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0291 0.0376
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0395 0.2376 0.8613
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0077 0.0098
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0111 0.061 0.0816
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0016 0.0041
Echinococcus multilocularis 0.0084 0.0437 0.0433
Schistosoma mansoni hypothetical protein 0.0296 0.1763 0.2371
Schistosoma mansoni hypothetical protein 0.0101 0.0548 0.0733
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0016 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0111 0.061 0.0816
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0084 0.0437 0.0583
Plasmodium falciparum ataxin-2 like protein, putative 0.0099 0.0534 0.223
Trichomonas vaginalis glucose-6-phosphate translocase, putative 0.0024 0.0064 0.0217
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0061 0.0062
Echinococcus granulosus pyruvate kinase 0.0017 0.0022 0.0023
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0055 0.0259 0.0923
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0395 0.2376 0.8613
Trypanosoma cruzi cysteine peptidase, putative 0.0395 0.2376 0.3198
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0121 0.0671 0.2419
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0157 0.0893 0.0889
Schistosoma mansoni histone deacetylase hda2 0.008 0.0415 0.0553
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0019 0.0004
Brugia malayi Matrixin family protein 0.0043 0.0185 0.0244
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0054 0.0251 0.0909
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0016 0.0015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0395 0.2376 0.8613
Schistosoma mansoni cathepsin F (C01 family) 0.0395 0.2376 0.3198
Giardia lamblia Hypothetical protein 0.0015 0.001 0.002
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0055 0.0258 0.0332
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0121 0.0671 0.2419
Giardia lamblia Hypothetical protein 0.0121 0.0671 0.2419
Plasmodium falciparum serine repeat antigen 1 0.0121 0.0671 0.2808
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0209 0.0275
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.2103 0.7623
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0083 0.0431 0.0575
Toxoplasma gondii protease inhibitor PI2 0.0055 0.0259 0.0923
Loa Loa (eye worm) hypothetical protein 0.0043 0.0185 0.0244
Loa Loa (eye worm) hypothetical protein 0.0023 0.0061 0.0076
Entamoeba histolytica hypothetical protein 0.0025 0.0071 0.0279
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0196 0.1138 0.1133
Trypanosoma cruzi MFS transporter, putative 0.008 0.0418 0.0557
Brugia malayi Cathepsin L-like precursor 0.0395 0.2376 0.3198
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0064 0.0217
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0789 0.1058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0395 0.2376 0.8616
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0037 0.0044
Entamoeba histolytica hypothetical protein 0.0121 0.0671 0.2808
Loa Loa (eye worm) hypothetical protein 0.1204 0.7418 1
Trypanosoma cruzi histone deacetylase 1, putative 0.0091 0.0482 0.0644
Brugia malayi hypothetical protein 0.008 0.0418 0.0557
Mycobacterium tuberculosis Probable reductase 0.0105 0.0571 0.082
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0016 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0395 0.2376 0.8613
Brugia malayi Cathepsin L-like precursor 0.0395 0.2376 0.3198
Plasmodium vivax unspecified product 0.0165 0.0943 0.3958
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0395 0.2376 0.8613
Leishmania major cathepsin L-like protease 0.0395 0.2376 0.8613
Loa Loa (eye worm) hypothetical protein 0.0148 0.084 0.1127
Onchocerca volvulus Prolyl endopeptidase homolog 0.0135 0.0757 0.3171
Brugia malayi cathepsin F-like cysteine proteinase 0.0121 0.0671 0.0898
Toxoplasma gondii transporter, major facilitator family protein 0.008 0.0418 0.1502
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0456 0.2757 0.3713
Brugia malayi CXXC zinc finger family protein 0.0021 0.0046 0.0055
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0143 0.0519
Loa Loa (eye worm) hypothetical protein 0.0055 0.0259 0.0343
Entamoeba histolytica cysteine protease, putative 0.0165 0.0943 0.3958
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0037 0.0044
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0055 0.0259 0.0343
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0016 0.0019 0.005
Loa Loa (eye worm) hypothetical protein 0.0351 0.2103 0.2831
Plasmodium vivax unspecified product 0.0121 0.0671 0.2808
Schistosoma mansoni pyruvate kinase 0.0017 0.0022 0.0023
Brugia malayi Cyclic-nucleotide gated cation channel 0.0016 0.0019 0.0018
Plasmodium vivax histone deacetylase, putative 0.0074 0.0378 0.1573
Brugia malayi Cathepsin L-like precursor 0.0395 0.2376 0.3198
Onchocerca volvulus 0.008 0.0418 0.1741
Giardia lamblia Cathepsin B precursor 0.0121 0.0671 0.2419
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0054 0.0251 0.3253
Echinococcus granulosus cpg binding protein 0.0022 0.0053 0.0065
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0148 0.084 0.1127
Toxoplasma gondii LsmAD domain-containing protein 0.0099 0.0534 0.1921
Entamoeba histolytica cysteine proteinase, putative 0.0165 0.0943 0.3958
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0395 0.2376 0.8613
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0143 0.0502
Echinococcus multilocularis dna polymerase eta 0.0019 0.0037 0.0033
Plasmodium vivax vivapain-1 0.0165 0.0943 0.3958
Mycobacterium tuberculosis Probable peptidase 0.0054 0.0251 0.0347
Plasmodium vivax histone deacetylase 2, putative 0.0074 0.0378 0.1573
Loa Loa (eye worm) histone deacetylase 7A 0.0074 0.0378 0.0503
Echinococcus granulosus histone deacetylase 0.0074 0.0378 0.0503
Loa Loa (eye worm) hypothetical protein 0.0121 0.0671 0.0898
Trypanosoma brucei unspecified product 0.0019 0.0037 0.0136
Onchocerca volvulus 0.0023 0.0061 0.0238
Loa Loa (eye worm) hypothetical protein 0.0395 0.2376 0.3198
Brugia malayi MH2 domain containing protein 0.0017 0.002 0.0021
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.002 0.0021
Echinococcus granulosus histone deacetylase 3 0.0091 0.0482 0.0644
Giardia lamblia Histone deacetylase 0.0091 0.0482 0.1734
Schistosoma mansoni smad1 5 8 and 0.0017 0.002 0.0021
Brugia malayi RNA, U transporter 1 0.0087 0.0457 0.0611
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0209 0.0204
Giardia lamblia Cathepsin B precursor 0.0456 0.2757 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0061 0.0205
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0571 0.082
Brugia malayi MH2 domain containing protein 0.0017 0.002 0.0021
Plasmodium falciparum serine repeat antigen 2 0.0121 0.0671 0.2808
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0122 0.0492
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0143 0.0174
Trypanosoma cruzi cysteine proteinase, putative 0.0165 0.0943 0.1266
Leishmania major GTP-binding protein, putative 0.0022 0.0057 0.0188
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0122 0.0157
Schistosoma mansoni DNA polymerase eta 0.0019 0.0037 0.0044
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0055 0.0259 0.0923
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0044 0.0189 0.0249
Loa Loa (eye worm) hypothetical protein 0.0033 0.0122 0.0157
Loa Loa (eye worm) hypothetical protein 0.0055 0.0259 0.0343
Leishmania major cathepsin L-like protease 0.0395 0.2376 0.8613
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0121 0.0671 0.0898
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0055 0.0258 0.0342
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0084 0.0437 0.1823
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0057 0.007
Onchocerca volvulus 0.0091 0.0485 0.2027
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0016 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0395 0.2376 0.8613
Plasmodium falciparum cysteine proteinase falcipain 3 0.0395 0.2376 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0135 0.0549
Echinococcus multilocularis pyruvate kinase 0.0026 0.0078 0.0074
Plasmodium vivax glutathione reductase, putative 0.0046 0.0204 0.0838
Echinococcus granulosus cathepsin l1 0.0395 0.2376 0.3198
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0135 0.0175
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0482 0.1734
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0122 0.0424
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0571 0.082
Loa Loa (eye worm) agrin synaptic family protein 0.0055 0.0259 0.0343
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0143 0.0186
Mycobacterium tuberculosis Possible penicillin-binding protein 0.071 0.4343 0.6392
Onchocerca volvulus 0.0395 0.2376 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0789 0.1058
Onchocerca volvulus 0.0021 0.0046 0.0173
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0456 0.2757 0.3713
Echinococcus granulosus histone deacetylase 1 0.0091 0.0482 0.0644
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0022 0.0072
Toxoplasma gondii cathepsin CPC1 0.0121 0.0671 0.2419
Loa Loa (eye worm) hypothetical protein 0.0351 0.2103 0.2831
Giardia lamblia Cathepsin L precursor 0.0121 0.0671 0.2419
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0122 0.0492
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0015 0.001 0.0024
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0015 0.001 0.0024
Giardia lamblia Cathepsin L-like protease 0.0121 0.0671 0.2419
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0091 0.0482 0.1734
Loa Loa (eye worm) hypothetical protein 0.0084 0.0437 0.0583
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0143 0.0502
Brugia malayi histone deacetylase 3 (HD3) 0.0091 0.0482 0.0644
Brugia malayi cathepsin Z-like cysteine proteinase 0.0121 0.0671 0.0898
Plasmodium falciparum cysteine proteinase falcipain 1 0.0165 0.0943 0.3958
Trypanosoma brucei glucosidase, putative 0.0035 0.0135 0.0489
Loa Loa (eye worm) hypothetical protein 0.008 0.0418 0.0557
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0121 0.0671 0.0898
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0395 0.2376 0.8616
Schistosoma mansoni histone deacetylase 4 5 0.0074 0.0378 0.0503
Mycobacterium tuberculosis Possible oxidoreductase 0.0084 0.0437 0.0622
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0044 0.0193 0.0189
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0135 0.0175
Onchocerca volvulus 0.0395 0.2376 1
Echinococcus granulosus smad 0.0017 0.002 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0037 0.0136
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0016 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0037 0.0136
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0037 0.0044
Loa Loa (eye worm) hypothetical protein 0.0111 0.061 0.0816
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0016 0.0015
Entamoeba histolytica cysteine protease, putative 0.0165 0.0943 0.3958
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0016 0.0048
Echinococcus multilocularis hyperpolarization activated cyclic 0.0016 0.0019 0.0014
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1186 0.7306 1
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0043 0.0185 0.0244
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0395 0.2376 0.8613
Onchocerca volvulus 0.0111 0.061 0.2551
Toxoplasma gondii ABC1 family protein 0.0111 0.061 0.2197
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0209 0.0204
Mycobacterium tuberculosis Probable esterase LipL 0.0111 0.061 0.0877
Giardia lamblia Cathepsin L precursor 0.0121 0.0671 0.2419
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0111 0.061 0.0814
Onchocerca volvulus 0.0048 0.0218 0.09
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0016 0.0015
Schistosoma mansoni importin beta-1 0.0031 0.0107 0.0138
Mycobacterium ulcerans hypothetical protein 0.0023 0.0061 0.0062
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0135 0.0175
Trichomonas vaginalis esterase, putative 0.0111 0.061 0.2197
Loa Loa (eye worm) hypothetical protein 0.0056 0.0266 0.0352
Plasmodium falciparum glutathione reductase 0.0046 0.0204 0.0838
Loa Loa (eye worm) MBCTL1 0.0053 0.0249 0.033
Echinococcus multilocularis hyperpolarization activated cyclic 0.0016 0.0019 0.0014
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0107 0.0388
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0395 0.2376 0.8613
Loa Loa (eye worm) glutathione reductase 0.0046 0.0204 0.0268
Trypanosoma cruzi histone deacetylase, putative 0.0074 0.0378 0.0503
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0571 0.8747
Loa Loa (eye worm) hypothetical protein 0.0023 0.0061 0.0076
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0148 0.084 0.1127
Brugia malayi cathepsin Z-like cysteine proteinase 0.0121 0.0671 0.0898
Echinococcus granulosus histone deacetylase 6 0.008 0.0415 0.0553
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0037 0.0136
Schistosoma mansoni organic anion transporter 0.008 0.0418 0.0557
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0121 0.0671 0.2419
Brugia malayi metabotropic glutamate receptor type 2 0.002 0.0044 0.0052
Onchocerca volvulus 0.0111 0.061 0.2551
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0395 0.2376 0.3198
Echinococcus granulosus cathepsin l cysteine peptidase 0.0395 0.2376 0.3198
Trypanosoma brucei PAB1-binding protein , putative 0.0099 0.0534 0.1935
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.0548 0.0733
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.09 0.1207
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.061 0.2197
Echinococcus multilocularis cathepsin L cysteine protease 0.0395 0.2376 0.2372
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0671 0.2419
Loa Loa (eye worm) hypothetical protein 0.0351 0.2103 0.2831
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0395 0.2376 0.8616
Echinococcus multilocularis cathepsin L 0.0165 0.0943 0.0939
Loa Loa (eye worm) hypothetical protein 0.008 0.0418 0.0557
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0025 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0165 0.0943 0.342
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0057 0.007
Mycobacterium ulcerans dehydrogenase 0.0084 0.0437 0.0578
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0122 0.0157
Schistosoma mansoni Smad4 0.0017 0.002 0.0021
Brugia malayi POT family protein 0.004 0.0167 0.0218
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0117 0.0644 0.0927
Plasmodium vivax serine-repeat antigen (SERA) 0.0121 0.0671 0.2808
Plasmodium falciparum histone deacetylase 2 0.0074 0.0378 0.1573
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0121 0.0671 0.0898
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0037 0.0136
Onchocerca volvulus 0.0121 0.0671 0.2808
Giardia lamblia Cathepsin B precursor 0.0121 0.0671 0.2419
Schistosoma mansoni cathepsin F (C01 family) 0.0395 0.2376 0.3198
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0061 0.0076
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0135 0.0549
Mycobacterium ulcerans hypothetical protein 0.0111 0.061 0.0814
Plasmodium falciparum histone deacetylase, putative 0.0074 0.0378 0.1573
Brugia malayi Cathepsin L-like precursor 0.0395 0.2376 0.3198
Echinococcus granulosus hyperpolarization activated cyclic 0.0016 0.0019 0.0018
Echinococcus granulosus cathepsin L cysteine proteinase 0.0395 0.2376 0.3198
Leishmania major cathepsin L-like protease 0.0395 0.2376 0.8613
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0395 0.2376 0.8613
Brugia malayi histone deacetylase 11 0.0047 0.0208 0.0274
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0107 0.0102
Plasmodium vivax serine-repeat antigen (SERA) 0.0121 0.0671 0.2808
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0209 0.0275
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.002 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0037 0.0136
Brugia malayi prolyl oligopeptidase family protein 0.0135 0.0757 0.1014
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0395 0.2376 0.8613
Trypanosoma cruzi cysteine peptidase, putative 0.0165 0.0943 0.1266
Brugia malayi hypothetical protein 0.0084 0.0437 0.0583
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.1102 0.6786 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0395 0.2376 0.8616
Loa Loa (eye worm) ctsf protein 0.0395 0.2376 0.3198
Giardia lamblia DINP protein human, muc B family 0.0019 0.0037 0.0119
Loa Loa (eye worm) hypothetical protein 0.0033 0.0123 0.016
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0037 0.0044
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0121 0.0671 0.2808
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0209 0.0275
Loa Loa (eye worm) hypothetical protein 0.0101 0.0548 0.0733
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0789 0.0785
Entamoeba histolytica cysteine proteinase, putative 0.0351 0.2103 0.8851
Schistosoma mansoni hypothetical protein 0.0047 0.0209 0.0275
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0351 0.2103 0.2831
Trypanosoma brucei oligopeptidase b 0.0054 0.0251 0.0909
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0064 0.0217
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0209 0.0275
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0071 0.024
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0061 0.0062
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0061 0.0067
Trypanosoma brucei prolyl endopeptidase 0.0135 0.0757 0.2744
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1204 0.7418 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0121 0.0671 0.2419
Brugia malayi Kelch motif family protein 0.0056 0.0266 0.0352
Brugia malayi Thioredoxin reductase 0.0046 0.0204 0.0268
Echinococcus granulosus tumor protein p63 0.0331 0.1976 0.2659
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0121 0.0671 0.2808
Mycobacterium tuberculosis Probable hydrolase 0.0111 0.061 0.0877
Brugia malayi Papain family cysteine protease containing protein 0.0121 0.0671 0.0898
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0055 0.0258 1
Schistosoma mansoni hypothetical protein 0.0047 0.0209 0.0275
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0083 0.0431 0.0575
Echinococcus multilocularis snurportin 1 0.0326 0.1947 0.1943
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0015 0.001 0.002
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0054 0.0251 0.0332
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0135 0.0472
Schistosoma mansoni cpg binding protein 0.0022 0.0053 0.0065
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0057 0.0188
Trypanosoma cruzi prolyl endopeptidase 0.0135 0.0757 0.1014
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0456 0.2757 1
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0015 0.001 0.0038
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0121 0.0671 0.2808
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0061 0.0062
Plasmodium vivax vivapain-3 0.0165 0.0943 0.3958
Plasmodium falciparum thioredoxin reductase 0.0016 0.0016 0.0048
Onchocerca volvulus 0.008 0.0418 0.1741
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0061 0.0062
Loa Loa (eye worm) hypothetical protein 0.0091 0.0482 0.0644
Plasmodium falciparum serine repeat antigen 6 0.0121 0.0671 0.2808
Brugia malayi MH1 domain containing protein 0.0017 0.002 0.0021
Echinococcus granulosus importin subunit beta 1 0.0031 0.0107 0.0138
Entamoeba histolytica cysteine protease, putative 0.0165 0.0943 0.3958
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.061 0.0816
Trichomonas vaginalis Regulatory protein uhpC, putative 0.0024 0.0064 0.0217
Echinococcus multilocularis pyruvate kinase 0.0017 0.0022 0.0017
Mycobacterium leprae Probable lipase LipE 0.0111 0.061 0.941
Brugia malayi sodium-independent organic anion transporter family protein 0.008 0.0418 0.0557
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0121 0.0671 0.2419
Schistosoma mansoni amine oxidase 0.0084 0.0437 0.0583
Echinococcus multilocularis cpg binding protein 0.0022 0.0053 0.0048
Onchocerca volvulus 0.0395 0.2376 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0121 0.0671 0.2808
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0015 0.001 0.0008
Leishmania major histone deacetylase, putative 0.0074 0.0378 0.1355
Loa Loa (eye worm) transcription factor SMAD2 0.0244 0.1438 0.1933
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0395 0.2376 0.8616
Schistosoma mansoni hypothetical protein 0.0044 0.0193 0.0254
Schistosoma mansoni organic anion transporter 0.008 0.0418 0.0557
Plasmodium falciparum serine repeat antigen 5 0.0121 0.0671 0.2808
Schistosoma mansoni pyruvate kinase 0.0033 0.0122 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0064 0.0217
Brugia malayi amine oxidase, flavin-containing family protein 0.0084 0.0437 0.0583
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0064 0.0217
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0121 0.0671 0.2419
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0122 0.0157
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0249 0.033
Leishmania major oligopeptidase b 0.0054 0.0251 0.0894
Echinococcus granulosus cathepsin b 0.1204 0.7418 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0571 0.082
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0055 0.0259 0.0343
Trypanosoma cruzi cysteine proteinase, putative 0.0165 0.0943 0.1266
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0037 0.0136
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0121 0.0671 0.0898
Plasmodium falciparum serine repeat antigen 3 0.0121 0.0671 0.2808
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0135 0.0757 0.1014
Mycobacterium ulcerans monoamine oxidase 0.0084 0.0437 0.0578
Toxoplasma gondii cathepsin CPL 0.0395 0.2376 0.8613
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0015 0.001 0.0006
Plasmodium falciparum glutathione reductase 0.0016 0.0016 0.0048
Echinococcus multilocularis GPCR, family 2 0.0047 0.0209 0.0204
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0055 0.0259 0.0343
Loa Loa (eye worm) cathepsin B 0.0456 0.2757 0.3713
Brugia malayi Histone deacetylase family protein 0.0074 0.0378 0.0503
Brugia malayi Matrixin family protein 0.0104 0.0566 0.0757
Treponema pallidum exodeoxyribonuclease (exoA) 0.0055 0.0258 1
Echinococcus granulosus histone deacetylase 6 0.0074 0.0378 0.0503
Toxoplasma gondii histone deacetylase HDAC2 0.0091 0.0482 0.1734
Brugia malayi exodeoxyribonuclease III family protein 0.0055 0.0258 0.0342
Entamoeba histolytica cysteine protease, putative 0.0121 0.0671 0.2808
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0111 0.061 0.0877
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0395 0.2376 0.8613
Giardia lamblia Cathepsin B precursor 0.0121 0.0671 0.2419
Loa Loa (eye worm) hypothetical protein 0.0084 0.0437 0.0583
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0084 0.0437 0.6451
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0071 0.024
Toxoplasma gondii histone deacetylase HDAC5 0.0047 0.0208 0.0739
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0671 0.2419
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0291 0.0376
Schistosoma mansoni hypothetical protein 0.0061 0.0298 0.0395
Onchocerca volvulus Matrilysin homolog 0.0043 0.0185 0.0761
Echinococcus granulosus histone deacetylase 7 0.0074 0.0378 0.0503
Brugia malayi beta-lactamase 0.0111 0.061 0.0816
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0395 0.2376 0.8613
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0143 0.0186
Loa Loa (eye worm) hypothetical protein 0.0099 0.0534 0.0713
Brugia malayi SWIRM domain containing protein 0.0084 0.0437 0.0583
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0024 0.0064 0.1997
Schistosoma mansoni histone deacetylase 0.0091 0.0482 0.0644
Loa Loa (eye worm) hypothetical protein 0.0121 0.0671 0.0898
Echinococcus granulosus geminin 0.0684 0.4181 0.5634
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0077 0.0397 0.1426
Toxoplasma gondii histone deacetylase HDAC1 0.0074 0.0378 0.1355
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0055 0.0258 0.0342
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0037 0.0033
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0291 0.0376
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0165 0.0943 0.3409
Echinococcus multilocularis follistatin 0.0055 0.0259 0.0254
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0143 0.0502
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0057 0.0219
Echinococcus multilocularis Solute carrier organic anion transporter family 0.008 0.0418 0.0413
Trypanosoma cruzi UDP-galactopyranose mutase 0.0084 0.0437 0.0583
Echinococcus granulosus cathepsin L cysteine protease 0.0165 0.0943 0.1266
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0121 0.0671 0.2808
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0107 0.0371
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0066 0.0082
Trypanosoma cruzi histone deacetylase, putative 0.0047 0.0208 0.0274
Mycobacterium tuberculosis Probable oxidoreductase 0.0117 0.0644 0.0927
Leishmania major pyruvate kinase 0.0033 0.0122 0.0424
Trichomonas vaginalis Hexuronate transporter, putative 0.0024 0.0064 0.0217
Entamoeba histolytica histone deacetylase, putative 0.0091 0.0482 0.2013
Schistosoma mansoni smad1 5 8 and 0.0017 0.002 0.0021
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0055 0.0258 0.0342
Loa Loa (eye worm) hypothetical protein 0.0053 0.0244 0.0322
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0016 0.0041
Echinococcus granulosus prolyl endopeptidase 0.0135 0.0757 0.1014
Schistosoma mansoni ap endonuclease 0.0055 0.0258 0.0342
Entamoeba histolytica cysteine protease, putative 0.0165 0.0943 0.3958
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0326 0.1947 0.2619
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0016 0.0015
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0122 0.0424
Echinococcus multilocularis pyruvate kinase 0.0033 0.0122 0.0117
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1204 0.7418 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0204 0.0268
Brugia malayi hypothetical protein 0.0099 0.0534 0.0713
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0122 0.1035
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0135 0.0472
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0143 0.5239
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.002 0.0021
Giardia lamblia Cathepsin L precursor 0.0121 0.0671 0.2419
Mycobacterium ulcerans esterase/lipase LipP 0.0111 0.061 0.0814
Loa Loa (eye worm) fibroinase 0.0395 0.2376 0.3198
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0022 0.0062
Leishmania major pyruvate kinase 0.0033 0.0122 0.0424
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0395 0.2376 0.8613
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0121 0.0671 0.2419
Loa Loa (eye worm) hypothetical protein 0.0084 0.0437 0.0583
Echinococcus multilocularis histone deacetylase 6 0.008 0.0415 0.041
Leishmania major cathepsin L-like protease 0.0395 0.2376 0.8613
Brugia malayi Inositol-1 0.0036 0.0143 0.0186
Entamoeba histolytica cysteine protease, putative 0.0165 0.0943 0.3958
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0084 0.0437 0.1823
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0143 0.0502
Schistosoma mansoni integrin beta subunit 0.0205 0.1195 0.1605
Onchocerca volvulus Cathepsin F homolog 0.0395 0.2376 1
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0249 0.033
Schistosoma mansoni amine oxidase 0.0084 0.0437 0.0583
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0048 0.0213 0.028
Loa Loa (eye worm) hypothetical protein 0.0084 0.0437 0.0583
Trypanosoma brucei trypanothione reductase 0.0046 0.0204 0.0738
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0055 0.0258 0.0358
Brugia malayi hypothetical protein 0.0056 0.0266 0.0352
Echinococcus granulosus dna polymerase kappa 0.0019 0.0037 0.0044
Brugia malayi Papain family cysteine protease containing protein 0.0165 0.0943 0.1266
Loa Loa (eye worm) MH2 domain-containing protein 0.0244 0.1438 0.1933
Trypanosoma cruzi cysteine protease, putative 0.0165 0.0943 0.1266
Brugia malayi Cytochrome P450 family protein 0.0026 0.0077 0.0098
Echinococcus granulosus dna polymerase eta 0.0019 0.0037 0.0044
Onchocerca volvulus Putative organic anion transporter 0.008 0.0418 0.1741
Echinococcus granulosus lysine specific histone demethylase 1A 0.0084 0.0437 0.0583
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.061 0.0816
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0571 0.082
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0037 0.0136
Onchocerca volvulus Matrix metalloproteinase homolog 0.0096 0.0513 0.2141
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0165 0.0943 0.342
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0121 0.0671 0.2808
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0209 0.0204
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0085 0.0445 0.1599
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0122 0.0157
Brugia malayi Cathepsin L-like precursor 0.0044 0.0189 0.0249
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0016 0.0048
Onchocerca volvulus 0.0351 0.2103 0.8851
Echinococcus granulosus cathepsin l1 0.0351 0.2103 0.2831
Loa Loa (eye worm) histone deacetylase 1 0.0091 0.0482 0.0644
Schistosoma mansoni histone deacetylase 0.0091 0.0482 0.0644
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0395 0.2376 0.8613
Brugia malayi fibroinase precursor 0.0121 0.0671 0.0898
Brugia malayi Cathepsin L-like precursor 0.0351 0.2103 0.2831
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0395 0.2376 0.8616
Brugia malayi Hemopexin family protein 0.0061 0.0298 0.0395
Echinococcus multilocularis cathepsin L cysteine protease 0.0395 0.2376 0.2372
Schistosoma mansoni pyruvate kinase 0.0033 0.0122 0.0157
Loa Loa (eye worm) hypothetical protein 0.0121 0.0671 0.0898
Schistosoma mansoni alpha glucosidase 0.0035 0.0135 0.0175
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0014 0.0005 0.0018
Entamoeba histolytica Ran family GTPase 0.0022 0.0057 0.0219
Loa Loa (eye worm) matrixin family protein 0.0104 0.0566 0.0757
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0121 0.0671 0.2419
Leishmania major hypothetical protein, conserved 0.0111 0.061 0.2197
Leishmania major cytochrome p450-like protein 0.0026 0.0077 0.0264
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0122 0.0492
Onchocerca volvulus 0.0084 0.0437 0.1823
Brugia malayi sodium-independent organic anion transporter family protein 0.008 0.0418 0.0557
Toxoplasma gondii histone deacetylase HDAC3 0.0091 0.0482 0.1734
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0027
Loa Loa (eye worm) hypothetical protein 0.0047 0.0209 0.0275
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0061 0.0062
Loa Loa (eye worm) hypothetical protein 0.008 0.0418 0.0557
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0055 0.0259 0.0343
Trichomonas vaginalis glucarate, hexuronate transporter, putative 0.0024 0.0064 0.0217
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0196 0.1138 0.1528
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0135 0.0472
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0066 0.0082
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0077 0.0098
Trichomonas vaginalis Regulatory protein uhpC, putative 0.0024 0.0064 0.0217
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0037 0.0119
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0135 0.0472
Onchocerca volvulus 0.0047 0.0209 0.0861
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0057 0.0206
Trypanosoma cruzi oligopeptidase b 0.0054 0.0251 0.0332
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0121 0.0671 0.2808
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0121 0.0671 0.2808
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0121 0.0671 0.2419
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0249 0.0245
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0111 0.061 0.0816
Trichomonas vaginalis histone deacetylase, putative 0.0091 0.0482 0.1734
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0016 0.0019 0.0014
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0037 0.0044
Echinococcus multilocularis pyruvate kinase 0.0017 0.0022 0.0017

Activities

Activity type Activity value Assay description Source Reference
% (functional) = 34.3 Percent packed cell volume at 10 mg/kg per day ChEMBL. 7277393
Days (functional) = 10.2 Effect of compound on P-388 lymphocytic leukemia growth at a given dose 15 mg/kg per day ip expressed as average survival days of treated mice ChEMBL. 7277393
Inhibition (functional) = 22.8 % Percent inhibition of ehrlich ascites carcinoma growth at 10 mg/kg per day ChEMBL. 7277393
Inhibition (functional) = 22.8 % Percent inhibition of ehrlich ascites carcinoma growth at 10 mg/kg per day ChEMBL. 7277393
Survivors at day 9 (functional) = 8 Effect on ehrlich ascites carcinoma growth in CF1 mice at 10 mg/kg per day ip survival at day 9; 8/8 ChEMBL. 7277393
T/C (functional) = 107 Effect of compound on P-388 lymphocytic leukemia growth at a given dose 15 mg/kg per day ip expressed as ratio of treated / control (T/C>125 is required for significant activity) ChEMBL. 7277393
Volume (functional) = 2.82 Percent packed cell volume at 10 mg/kg per day per mouse ChEMBL. 7277393

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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