Detailed information for compound 290460

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 323.407 | Formula: C16H21NO4S
  • H donors: 1 H acceptors: 3 LogP: 1.69 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: SCC(C(=O)N1C[C@H](C[C@H]1C(=O)O)OCc1ccccc1)C
  • InChi: 1S/C16H21NO4S/c1-11(10-22)15(18)17-8-13(7-14(17)16(19)20)21-9-12-5-3-2-4-6-12/h2-6,11,13-14,22H,7-10H2,1H3,(H,19,20)/t11?,13-,14-/m0/s1
  • InChiKey: BFBWLUZWZHHCIC-VNXPTHQBSA-N  


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Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis PIKK family atypical protein kinase 0.0357 0.0596 0.3952
Echinococcus granulosus dna polymerase kappa 0.0019 0.0012 0.0012
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0013 0.0002 0.0011
Trypanosoma brucei Casein kinase II 0.0145 0.0231 0.1534
Echinococcus multilocularis histone deacetylase 6 0.0678 0.1152 0.1152
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0058 0.0287
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0013 0.0085
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1648 0.2831 0.2831
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0118 0.0184 0.0804
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0677 0.1151 0.5035
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0015 0.0688
Toxoplasma gondii hypothetical protein 0.0021 0.0015 0.0099
Plasmodium falciparum histone deacetylase 2 0.0678 0.1152 0.7665
Schistosoma mansoni hypothetical protein 0.0054 0.0073 0.0321
Trypanosoma brucei histone deacetylase 3 0.0678 0.1152 0.7665
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0179 0.0782
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0037 0.1654
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0309 0.0514 0.2245
Trichomonas vaginalis PIKK family atypical protein kinase 0.0537 0.0909 0.6027
Entamoeba histolytica serine/threonine protein kinase, putative 0.0203 0.0331 0.2194
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0212 0.0346 0.1001
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0037 0.0183
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0006 0.0037
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0118 0.0184 0.1218
Trichomonas vaginalis CMGC family protein kinase 0.0145 0.0231 0.1528
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0086 0.0374
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0019 0.0597
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.001
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0118 0.0184 0.0184
Echinococcus granulosus tar DNA binding protein 0.0126 0.0197 0.0197
Loa Loa (eye worm) hypothetical protein 0.036 0.0603 0.2969
Trichomonas vaginalis histone deacetylase, putative 0.0881 0.1503 0.9964
Entamoeba histolytica protein kinase domain containing protein 0.0054 0.0073 0.0482
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0019 0.0013 0.0085
Plasmodium vivax SET domain protein, putative 0.0061 0.0086 0.0568
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0141
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0045
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0542 0.0918 0.6106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0562 0.0952 0.6307
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0657 0.1116 0.7398
Plasmodium vivax unspecified product 0.0145 0.0231 0.1534
Loa Loa (eye worm) hypothetical protein 0.0326 0.0544 0.2679
Schistosoma mansoni tar DNA-binding protein 0.0126 0.0197 0.086
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0021 0.0015 0.042
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0085
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0212 0.0346 0.2294
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0033 0.0218
Echinococcus multilocularis 6 phosphofructokinase 0.0115 0.0179 0.0179
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.002 0.0097
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0013 0.0085
Loa Loa (eye worm) CHromoDomain protein family member 0.0012 0 0.000000000032549
Trichomonas vaginalis PIKK family atypical protein kinase 0.0498 0.0842 0.558
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0118 0.0184 0.0184
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0013 0.0002 0.001
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0012 0.0034
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0002 0.0006
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0033 0.022
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0037 0.0246
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0012 0.0078
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0002 0.0014
Giardia lamblia DINP protein human, muc B family 0.0019 0.0012 0.0064
Chlamydia trachomatis DNA ligase 0.0019 0.0013 0.2971
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0562 0.0952 0.6307
Plasmodium vivax histone deacetylase 1, putative 0.0881 0.1503 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0045
Schistosoma mansoni regulator of G protein signaling 0.002 0.0015 0.0064
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.045 0.0758 0.5022
Trichomonas vaginalis conserved hypothetical protein 0.0012 0 0.0000039333
Brugia malayi SH2 domain containing protein 0.036 0.0603 0.3997
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0033 0.022
Loa Loa (eye worm) hypothetical protein 0.0061 0.0086 0.0421
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0047 0.0299
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0118 0.0184 0.0531
Schistosoma mansoni hypothetical protein 0.0031 0.0033 0.0145
Loa Loa (eye worm) hypothetical protein 0.0293 0.0487 0.2396
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0091 0.0605
Plasmodium falciparum casein kinase 2, alpha subunit 0.0145 0.0231 0.1534
Schistosoma mansoni atypical protein kinase C 0.0013 0.0003 0.0011
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0118 0.0184 0.0804
Trichomonas vaginalis PIKK family atypical protein kinase 0.0118 0.0184 0.1218
Schistosoma mansoni pyruvate kinase 0.0033 0.0037 0.0163
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0142 0.0225 0.1106
Trypanosoma brucei histone deacetylase, putative 0.0678 0.1152 0.7665
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0033 0.022
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0012 0.0078
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0212 0.0346 0.2294
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0 0.0000039333
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0293 0.0487 0.1407
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0063
Plasmodium vivax hypothetical protein, conserved 0.0012 0 0.000000000043978
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0002 0.0014
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0118 0.0184 0.1218
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0039 0.0047 0.0314
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0562 0.0952 0.0952
Trichomonas vaginalis chromobox protein, putative 0.0012 0 0.0000039333
Trichomonas vaginalis PIKK family atypical protein kinase 0.0518 0.0876 0.5804
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0012 0.0078
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0884 0.1509 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0047 0.0313
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0033 0.022
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.0149 0.0988
Entamoeba histolytica hypothetical protein 0.0012 0 0.0000039333
Loa Loa (eye worm) RGS-3 protein 0.002 0.0015 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0518 0.0876 0.5804
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0019 0.0667
Schistosoma mansoni rac gtpase activating protein 0.0071 0.0103 0.0451
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0016
Brugia malayi Associated with TFs and helicases family protein 0.0012 0 0.00000000004382
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0095
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0012 0.0238
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.019 0.0307 0.1513
Mycobacterium ulcerans hypothetical protein 0.0023 0.0019 0.0597
Loa Loa (eye worm) phosphatidylinositol 3 0.1186 0.2031 1
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0118 0.0184 0.1223
Schistosoma mansoni tar DNA-binding protein 0.0126 0.0197 0.086
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0179 0.0517
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0028 0.0139
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0065 0.0091 0.0605
Loa Loa (eye worm) hypothetical protein 0.0031 0.0033 0.0162
Loa Loa (eye worm) hypothetical protein 0.0034 0.0038 0.0187
Brugia malayi PAS domain containing protein 0.0052 0.0069 0.0454
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0033 0.0033
Schistosoma mansoni topbp1 0.0019 0.0013 0.0056
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.0003 0.0011
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0047 0.0308
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0118 0.0184 0.0531
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0341 0.0569 0.28
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0047 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.0351 0.0588 0.2893
Brugia malayi Uncoordinated protein 44 0.0015 0.0006 0.0037
Trypanosoma brucei polo-like protein kinase 0.0203 0.0331 0.2202
Loa Loa (eye worm) hypothetical protein 0.0205 0.0335 0.1647
Schistosoma mansoni histone deacetylase 0.0881 0.1503 0.6573
Loa Loa (eye worm) phosphofructokinase 0.0115 0.0179 0.088
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0034 0.0038 0.0038
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0065 0.0091 0.0091
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0071
Echinococcus granulosus expressed conserved protein 0.0086 0.0129 0.0129
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.001
Echinococcus multilocularis pyruvate kinase 0.0026 0.0025 0.0025
Trichomonas vaginalis Heterochromatin protein, putative 0.0012 0 0.0000039333
Schistosoma mansoni hypothetical protein 0.0086 0.0129 0.0564
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0212 0.0346 0.2303
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0012 0.0078
Plasmodium falciparum replication factor C subunit 1, putative 0.0019 0.0013 0.0085
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0 0.0000039333
Loa Loa (eye worm) histone deacetylase 0.0678 0.1152 0.5673
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0019 0.0053
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0071
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0095
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0037 0.0454
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0106 0.0106
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0019 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0012 0 0.0000039333
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0013 0.0002 0.0011
Echinococcus granulosus protein kinase shaggy 0.0054 0.0073 0.0073
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0881 0.1503 0.9964
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0037 0.0247
Leishmania major phosphatidylinositol 3-kinase, putative 0.0212 0.0346 0.0945
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0013 0.0085
Trichomonas vaginalis CAMK family protein kinase 0.0203 0.0331 0.2194
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0179 0.0782
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0021 0.0091
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0034 0.0038 0.0038
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0002 0.0014
Entamoeba histolytica hypothetical protein 0.0019 0.0013 0.0085
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0 0.0000039333
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0034 0.0038 0.0038
Plasmodium falciparum histone deacetylase 1 0.0881 0.1503 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0091 0.0605
Plasmodium vivax replication factor C subunit 1, putative 0.0019 0.0013 0.0085
Echinococcus granulosus lamin dm0 0.0028 0.0028 0.0028
Brugia malayi acetyltransferase, GNAT family protein 0.0145 0.0231 0.1531
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0011 0.0031
Brugia malayi Casein kinase II, alpha chain 0.0145 0.0231 0.1528
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.5791 1 1
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0324 0.0539 0.3586
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0082 0.0082
Giardia lamblia Pyruvate kinase 0.0033 0.0037 0.0233
Schistosoma mansoni survival motor neuron protein 0.0102 0.0156 0.0681
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0205 0.0335 0.0335
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0002 0.0014
Echinococcus multilocularis protein kinase c iota type 0.0013 0.0003 0.0003
Brugia malayi hypothetical protein 0.002 0.0015 0.0096
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0145 0.0231 0.1534
Schistosoma mansoni axis inhibition protein axin 0.002 0.0015 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0156 0.1034
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0086 0.0568
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0058 0.0386
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0044 0.0056 0.0368
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0012 0 0.0001
Echinococcus granulosus nibrin 0.0019 0.0013 0.0013
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0552 0.0934 0.0934
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0003 0.0016
Brugia malayi hypothetical protein 0.002 0.0015 0.0096
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0002 0.0014
Trypanosoma cruzi histone deacetylase, putative 0.0351 0.0588 0.1698
Brugia malayi histone deacetylase 3 (HD3) 0.0881 0.1503 0.9964
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.019 0.0307 0.2036
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0012 0.0034
Trypanosoma cruzi histone deacetylase, putative 0.0678 0.1152 0.3331
Trichomonas vaginalis PIKK family atypical protein kinase 0.0523 0.0884 0.5861
Plasmodium falciparum GAF domain-related protein, putative 0.0021 0.0015 0.0099
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0012 0.0078
Echinococcus multilocularis protein kinase c epsilon type 0.0014 0.0004 0.0004
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0054 0.0073 0.0319
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1334 0.2287 1
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0013 0.0085
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0011 0.0072
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0063
Echinococcus granulosus 6 phosphofructokinase 0.0115 0.0179 0.0179
Brugia malayi Histone deacetylase 1 0.0881 0.1503 0.9964
Trichomonas vaginalis PIKK family atypical protein kinase 0.0542 0.0918 0.6083
Schistosoma mansoni hypothetical protein 0.0012 0 0.0001
Schistosoma mansoni hypothetical protein 0.0073 0.0106 0.0462
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0091 0.0605
Trypanosoma cruzi Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0013 0.0002 0.0006
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0015 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0012 0.0078
Echinococcus multilocularis Zinc finger, PHD finger 0.0212 0.0346 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0015 0.0096
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0065 0.0091 0.0399
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0003 0.0016
Trypanosoma brucei Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0013 0.0002 0.0014
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0212 0.0346 0.2303
Trichomonas vaginalis PIKK family atypical protein kinase 0.0498 0.0842 0.558
Schistosoma mansoni pyruvate kinase 0.0017 0.0009 0.004
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0341 0.0569 0.6918
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0003 0.0003
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0498 0.0842 0.5601
Loa Loa (eye worm) phosphatidylinositol kinase 0.0118 0.0184 0.0905
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0013 0.0002 0.0002
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0293 0.0487 0.0487
Brugia malayi hypoxia-induced factor 1 0.016 0.0256 0.1694
Trichomonas vaginalis CAMK family protein kinase 0.0203 0.0331 0.2194
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0039 0.0047 0.0308
Echinococcus granulosus nuclear factor of activated T cells 5 0.0078 0.0114 0.0114
Brugia malayi TAR-binding protein 0.0126 0.0197 0.1303
Brugia malayi BRCA1-associated protein 2 containing protein 0.0013 0.0002 0.0014
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.001 0.0044
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0212 0.0346 0.0346
Brugia malayi hypothetical protein 0.0019 0.0013 0.0085
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0033 0.0033
Trypanosoma brucei unspecified product 0.0013 0.0002 0.0011
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0033 0.022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0 0.0000039333
Loa Loa (eye worm) CYP4Cod1 0.0021 0.0015 0.0073
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0266 0.044 0.2915
Leishmania major DNA polymerase eta, putative 0.0019 0.0012 0.0032
Plasmodium vivax hypothetical protein 0.0118 0.0184 0.1223
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0179 0.1185
Echinococcus granulosus histone deacetylase 7 0.0678 0.1152 0.1152
Echinococcus granulosus histone deacetylase 8 0.0351 0.0588 0.0588
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0011 0.0072
Echinococcus multilocularis serine protein kinase ATM 0.0309 0.0514 0.0514
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0145 0.0231 0.1135
Leishmania major hypothetical protein, conserved 0.0013 0.0002 0.0006
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0 0.0000039333
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0028 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0012 0 0.0000039333
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0053 0.0354
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0006 0.0006
Schistosoma mansoni regulator of G protein signaling 0.002 0.0015 0.0064
Schistosoma mansoni chromobox protein 0.0012 0 0.0001
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0006 0.007
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0047 0.0308
Echinococcus granulosus axis inhibition protein axin 0.002 0.0015 0.0015
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0118 0.0184 0.0531
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0015 0.0015
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0073 0.0482
Entamoeba histolytica hypothetical protein 0.0118 0.0184 0.1218
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0014
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0065 0.0091 0.0605
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0118 0.0184 0.1218
Schistosoma mansoni aryl hydrocarbon receptor 0.0052 0.0069 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0078 0.0513
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0002 0.0014
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0118 0.0184 0.1223
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0078 0.0114 0.0114
Onchocerca volvulus Histone deacetylase 10 homolog 0.0351 0.0588 0.7147
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0037 0.0247
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.036 0.0602 0.3991
Schistosoma mansoni hypothetical protein 0.0031 0.0033 0.0145
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0014 0.0004 0.002
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0012 0.0032
Echinococcus multilocularis replication factor c subunit 1 0.0019 0.0013 0.0013
Entamoeba histolytica hypothetical protein 0.0012 0 0.0000039333
Brugia malayi PXA domain containing protein 0.0022 0.0017 0.0113
Schistosoma mansoni hypothetical protein 0.0031 0.0033 0.0145
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0015 0.0006 0.0006
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0065 0.0091 0.0605
Echinococcus multilocularis histone deacetylase 8 0.0351 0.0588 0.0588
Brugia malayi hypothetical protein 0.0151 0.0241 0.1598
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0054 0.0073 0.0073
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0011 0.0072
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0024 0.0021 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.0003 0.0011
Schistosoma mansoni netrin receptor unc5 0.0015 0.0006 0.0025
Schistosoma mansoni pyruvate kinase 0.0033 0.0037 0.0163
Loa Loa (eye worm) phosphatidylinositol 3 0.0118 0.0184 0.0905
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0562 0.0952 0.2751
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0015 0.0043
Schistosoma mansoni voltage-gated cation channel 0.0034 0.0038 0.0167
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0019 0.0128
Brugia malayi Variant SH3 domain containing protein 0.0015 0.0006 0.0036
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0212 0.0346 0.2303
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0019 0.0013 0.0569
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0065 0.0091 0.0607
Leishmania major pyruvate kinase 0.0033 0.0037 0.0102
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.0002 0.0011
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0013 0.0002 0.0014
Echinococcus granulosus pyruvate kinase 0.0017 0.0009 0.0009
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0003 0.0016
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0033 0.022
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0071
Echinococcus multilocularis histone deacetylase 7 0.0678 0.1152 0.1152
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0212 0.0346 0.2294
Brugia malayi RhoGAP domain containing protein 0.0015 0.0006 0.0037
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0019 0.0128
Brugia malayi serine/threonine-protein kinase plk-2 0.0203 0.0331 0.2194
Loa Loa (eye worm) phosphatidylinositol 3 0.0118 0.0184 0.0905
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0033 0.022
Trichomonas vaginalis chromobox protein, putative 0.0012 0 0.0000039333
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0015 0.0064
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0013 0.0002 0.0014
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0552 0.0934 0.6192
Loa Loa (eye worm) calcium channel 0.0034 0.0038 0.0187
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0012 0.0052
Onchocerca volvulus 0.0151 0.0241 0.2933
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0012 0.0034
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0 0.0000039333
Giardia lamblia GTOR 0.0562 0.0952 0.6324
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.0324 0.0539 0.2654
Loa Loa (eye worm) histone deacetylase 1 0.0881 0.1503 0.7401
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0085
Trichomonas vaginalis chromobox protein, putative 0.0012 0 0.0000039333
Schistosoma mansoni chromobox protein 0.0012 0 0.0001
Echinococcus multilocularis voltage dependent calcium channel 0.0034 0.0038 0.0038
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0003 0.0016
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0065 0.0091 0.0605
Loa Loa (eye worm) hypothetical protein 0.034 0.0567 0.2791
Trichomonas vaginalis PIKK family atypical protein kinase 0.0537 0.0909 0.6027
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0126 0.0197 0.0968
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0037 0.0454
Brugia malayi Pax transcription activation domain interacting protein 0.0019 0.0013 0.0085
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0013 0.0002 0.001
Brugia malayi phosphofructokinase 0.0115 0.0179 0.1184
Echinococcus granulosus casein kinase ii subunit beta 0.0039 0.0047 0.0047
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0029 0.0029 0.019
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0073 0.0482
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0012 0 0.0000039333
Leishmania major histone deacetylase, putative 0.0678 0.1152 0.3145
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0063
Brugia malayi 6-phosphofructokinase 0.0115 0.0179 0.1184
Loa Loa (eye worm) hypothetical protein 0.0039 0.0047 0.0233
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0039 0.0047 0.0047
Giardia lamblia Casein kinase II beta chain 0.0039 0.0047 0.0295
Onchocerca volvulus 0.0023 0.0019 0.0236
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0118 0.0184 0.1218
Echinococcus multilocularis 0.0118 0.0184 0.0184
Schistosoma mansoni regulator of G protein signaling 0.002 0.0015 0.0064
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0011 0.0191
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0065 0.0091 0.0605
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0092 0.0138 0.0138
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0562 0.0952 0.6307
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0017 0.0009 0.0025
Loa Loa (eye worm) hypothetical protein 0.0173 0.0279 0.1372
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0309 0.0514 0.1484
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0115 0.0179 1
Trichomonas vaginalis histone deacetylase, putative 0.0881 0.1503 0.9964
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0078 0.0513
Echinococcus granulosus axis inhibition protein axin 0.002 0.0015 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0138 0.0217 0.1441
Brugia malayi Protein kinase domain containing protein 0.0013 0.0003 0.0016
Giardia lamblia Replication factor C, subunit 1 0.0019 0.0013 0.0071
Entamoeba histolytica hypothetical protein 0.0073 0.0106 0.07
Brugia malayi Protein kinase c protein 2 0.0014 0.0004 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0225 0.0983
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.036 0.0602 0.3991
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0003 0.0003
Leishmania major phosphatidylinositol kinase related protein, putative 0.0134 0.0211 0.0575
Brugia malayi Cytochrome P450 family protein 0.0031 0.0034 0.0224
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0179 0.1185
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0 0.0000039333
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0013 0.0003 0.0012
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0118 0.0184 0.0184
Giardia lamblia Kinase, PLK 0.0203 0.0331 0.219
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0047 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0498 0.0842 0.558
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0191 0.0309 0.0893
Echinococcus multilocularis pyruvate kinase 0.0017 0.0009 0.0009
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.0002 0.0011
Brugia malayi Histone deacetylase family protein 0.0678 0.1152 0.7638
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0018 0.0018
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0 0.00000000004382
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0015 0.0096
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0013 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0071
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0203 0.0331 0.163
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0562 0.0952 0.6307
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0095 0.0143 0.0625
Plasmodium vivax histone deacetylase 2, putative 0.0678 0.1152 0.7665
Trichomonas vaginalis hypothetical protein 0.0012 0 0.0000039333
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0005 0.0035
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0013 0.0037
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0033 0.022
Echinococcus multilocularis histone deacetylase 0.0678 0.1152 0.1152
Onchocerca volvulus Serine\/threonine kinase homolog 0.0203 0.0331 0.4027
Schistosoma mansoni regulator of G protein signaling 0.002 0.0015 0.0064
Giardia lamblia Kinase, CMGC GSK 0.0054 0.0073 0.047
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0039 0.0047 0.0313
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0019 0.0597
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0009 0.0061
Loa Loa (eye worm) phosphatidylinositol 3 0.0118 0.0184 0.0905
Leishmania major cytochrome p450-like protein 0.0021 0.0015 0.004
Entamoeba histolytica hypothetical protein 0.0073 0.0106 0.07
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0309 0.0514 0.3416
Loa Loa (eye worm) phosphatidylinositol 3 0.0562 0.0952 0.4685
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0011 0.0054
Brugia malayi hypothetical protein 0.0107 0.0164 0.1086
Loa Loa (eye worm) Csnk2b protein 0.0039 0.0047 0.0229
Leishmania major histone deacetylase, putative 0.0881 0.1503 0.4103
Schistosoma mansoni kinase 0.0105 0.0161 0.0702
Mycobacterium ulcerans putative regulatory protein 0.0021 0.0015 0.034
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0058 0.0255
Onchocerca volvulus 0.0118 0.0184 0.2237
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0118 0.0184 0.0531
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0118 0.0184 0.1223
Trichomonas vaginalis PIKK family atypical protein kinase 0.0537 0.0909 0.6027
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0015 0.0096
Echinococcus granulosus tumor protein p63 0.0358 0.0599 0.0599
Trichomonas vaginalis conserved hypothetical protein 0.0175 0.0282 0.187
Loa Loa (eye worm) acetyltransferase 0.0145 0.0231 0.1137
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0884 0.1509 0.4361
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0013 0.0002 0.0014
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0015 0.0064
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0013 0.0002 0.0014
Brugia malayi topoisomerase 0.0019 0.0013 0.0085
Leishmania major phosphatidylinositol kinase, putative 0.0118 0.0184 0.0502
Trichomonas vaginalis BRCA1-associated protein, putative 0.0013 0.0002 0.0014
Brugia malayi RhoGAP domain containing protein 0.0071 0.0103 0.0682
Echinococcus multilocularis tumor protein p63 0.0358 0.0599 0.0599
Leishmania major protein kinase, putative 0.0017 0.0009 0.0024
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0037 0.0247
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0045
Onchocerca volvulus 0.0107 0.0164 0.1991
Trichomonas vaginalis CMGC family protein kinase 0.0145 0.0231 0.1528
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0033 0.022
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0002 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0085
Trichomonas vaginalis CMGC family protein kinase 0.0145 0.0231 0.1528
Brugia malayi RhoGAP domain containing protein 0.0062 0.0086 0.057
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.036 0.0602 0.3991
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0884 0.1509 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0065 0.0091 0.0605
Echinococcus granulosus N chimaerin 0.0015 0.0006 0.0006
Echinococcus granulosus expressed protein 0.0396 0.0664 0.0664
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0013 0.0002 0.001
Schistosoma mansoni chromobox protein 0.0012 0 0.0001
Brugia malayi hypothetical protein 0.0499 0.0844 0.5592
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0011 0.0011
Echinococcus granulosus histone deacetylase 6 0.0691 0.1175 0.1175
Toxoplasma gondii histone deacetylase HDAC2 0.0881 0.1503 1
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0039 0.0047 0.0567
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0091 0.0605
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.0002 0.0014
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0053 0.0353
Trypanosoma brucei histone deacetylase 4 0.0678 0.1152 0.7665
Toxoplasma gondii FATC domain-containing protein 0.0309 0.0514 0.3416
Trichomonas vaginalis PIKK family atypical protein kinase 0.0537 0.0909 0.6027
Echinococcus multilocularis high voltage activated calcium channel beta 0.0092 0.0139 0.0139
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0047 0.0308
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0033 0.0218
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0033 0.0162
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0009 0.0061
Echinococcus granulosus survival motor neuron protein 1 0.0499 0.0844 0.0844
Trypanosoma cruzi histone deacetylase 1, putative 0.0881 0.1503 0.4345
Brugia malayi Protein kinase domain containing protein 0.0341 0.0569 0.3769
Loa Loa (eye worm) hypothetical protein 0.0052 0.007 0.0345
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0341 0.0569 0.0569
Echinococcus multilocularis protein kinase shaggy 0.0054 0.0073 0.0073
Toxoplasma gondii ATPase, AAA family protein 0.0019 0.0013 0.0085
Echinococcus multilocularis pyruvate kinase 0.0033 0.0037 0.0037
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0293 0.0487 0.0487
Brugia malayi protein kinase C3,putative 0.0013 0.0003 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.051 0.0862 0.5711
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0013 0.0002 0.0002
Echinococcus granulosus geminin 0.0677 0.1151 0.1151
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0341 0.0569 0.3769
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0021 0.0091
Schistosoma mansoni hypothetical protein 0.0677 0.1151 0.5035
Onchocerca volvulus 0.0054 0.0073 0.0887
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0015 0.0015
Brugia malayi Pre-SET motif family protein 0.0428 0.072 0.477
Echinococcus multilocularis beta adrenergic receptor kinase 0.0024 0.0021 0.0021
Leishmania major phosphatidylinositol 3-related kinase, putative 0.051 0.0862 0.2352
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0766 0.1304 0.8644
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0018 0.012
Schistosoma mansoni hypothetical protein 0.0015 0.0006 0.0025
Echinococcus multilocularis pyruvate kinase 0.0017 0.0009 0.0009
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0212 0.0346 0.0346
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0102 0.0156 0.1031
Plasmodium falciparum casein kinase II beta chain 0.0039 0.0047 0.0309
Leishmania major phosphatidylinositol 4-kinase, putative 0.0118 0.0184 0.0502
Trypanosoma cruzi hypothetical protein, conserved 0.2011 0.3459 1
Toxoplasma gondii hypothetical protein 0.0021 0.0015 0.0099
Entamoeba histolytica hypothetical protein 0.0118 0.0184 0.1218
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0012 0.0078
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0212 0.0346 0.1514
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0006 0.0006
Onchocerca volvulus Uncharacterized RING finger protein homolog 0.0013 0.0002 0.0028
Leishmania major histone deacetylase, putative 0.0678 0.1152 0.3145
Schistosoma mansoni topbp1 0.0019 0.0013 0.0056
Trichomonas vaginalis histone deacetylase, putative 0.0881 0.1503 0.9964
Echinococcus granulosus Rac GTPase activating protein 1 0.0071 0.0103 0.0103
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.0149 0.0988
Schistosoma mansoni single-minded 0.0052 0.0069 0.03
Brugia malayi intracellular kinase 0.0054 0.0073 0.0482
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0013 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0028
Echinococcus multilocularis BRCA1 associated protein 0.0013 0.0002 0.0002
Echinococcus granulosus Protein kinase C brain isozyme 0.0014 0.0004 0.0004
Plasmodium vivax glycogen synthase kinase 3, putative 0.0054 0.0073 0.0484
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0012 0.0078
Trypanosoma cruzi target of rapamycin kinase 3 0.0542 0.0918 0.2653
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0011 0.0072
Echinococcus granulosus protein kinase c epsilon type 0.0014 0.0004 0.0004
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0053 0.0354
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0134 0.0211 0.0609
Brugia malayi Csnk2b protein 0.0039 0.0047 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0015 0.0096
Mycobacterium ulcerans putative regulatory protein 0.0021 0.0015 0.034
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0029 0.0029 0.019
Schistosoma mansoni hypothetical protein 0.0102 0.0156 0.0681
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0004 0.0018
Brugia malayi histone deacetylase 1 (HD1) 0.0881 0.1503 0.9964
Echinococcus granulosus pyruvate kinase 0.0033 0.0037 0.0037
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0013 0.0002 0.0014
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0033 0.8832
Schistosoma mansoni tar DNA-binding protein 0.0126 0.0197 0.086
Echinococcus multilocularis histone deacetylase 6 0.0678 0.1152 0.1152
Trichomonas vaginalis brca1-associated protein, putative 0.0013 0.0002 0.0014
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0006 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0305 0.0506 0.3356
Entamoeba histolytica hypothetical protein 0.0309 0.0514 0.3403
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0045
Giardia lamblia Histone deacetylase 0.0881 0.1503 1
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0012 0 0.000000000043978
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0003 0.0003
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0015 0.0015
Leishmania major protein kinase, putative 0.0017 0.0009 0.0024
Schistosoma mansoni chromobox protein 0.0012 0 0.0001
Echinococcus multilocularis casein kinase ii subunit beta 0.0039 0.0047 0.0047
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0092 0.0138 0.0138
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0058 0.0058
Trypanosoma brucei unspecified product 0.0019 0.0012 0.0078
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0011 0.0058
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0011 0.0072
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0562 0.0952 0.633
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0078 0.0513
Entamoeba histolytica protein kinase, putative 0.0054 0.0073 0.0482
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0019 0.0128
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0203 0.0331 0.0331
Schistosoma mansoni protein kinase C mu 0.0013 0.0003 0.0011
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0033 0.022
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0251 0.0413 0.2033
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0179 0.1189
Brugia malayi Cytochrome P450 family protein 0.0021 0.0015 0.0098
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0118 0.0184 0.0184
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0013 0.0002 0.0006
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0033 0.022
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0212 0.0346 0.2294
Trichomonas vaginalis conserved hypothetical protein 0.0205 0.0335 0.2218
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0341 0.0569 0.28
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0014 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0324 0.0539 0.3573
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0006 0.0006
Trypanosoma brucei unspecified product 0.0013 0.0002 0.0011
Giardia lamblia Phosphatidylinositol 4-kinase 0.0118 0.0184 0.121
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0095 0.0632
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0509 0.086 0.5715
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0091 0.0605
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0411 0.069 0.3016
Entamoeba histolytica hypothetical protein 0.0073 0.0106 0.07
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0039 0.0047 0.0313
Trichomonas vaginalis PIKK family atypical protein kinase 0.0337 0.0563 0.3728
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0203 0.0331 0.0903
Entamoeba histolytica histone deacetylase, putative 0.0881 0.1503 0.9964
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0029 0.0029 0.019
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0054 0.0073 0.0484
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0012 0.0078
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0 0.0001
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0015 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0175 0.0282 0.187
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0019 0.0128
Giardia lamblia Hypothetical protein 0.0118 0.0184 0.121
Loa Loa (eye worm) PXA domain-containing protein 0.0022 0.0017 0.0084
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.0002 0.0011
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0015 0.0015
Onchocerca volvulus 0.0028 0.0028 0.0346
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0242 0.0398 0.1149
Schistosoma mansoni ap endonuclease 0.0018 0.0011 0.0048
Brugia malayi DKFZp564C0469 protein 0.0019 0.0013 0.0085
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0015 0.0015
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0015 0.0064
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0408 0.0686 0.4544
Echinococcus granulosus replication factor c subunit 1 0.0019 0.0013 0.0013
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0212 0.0346 0.2294
Loa Loa (eye worm) hypothetical protein 0.0067 0.0095 0.0469
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0091 0.0605
Echinococcus granulosus histone deacetylase 0.0678 0.1152 0.1152
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0034 0.0038 0.0167
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0562 0.0952 0.2751
Entamoeba histolytica hypothetical protein 0.0118 0.0184 0.1218
Trichomonas vaginalis histone deacetylase, putative 0.0881 0.1503 0.9964
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0019 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0293 0.0487 0.3225
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0054 0.0073 0.0358
Trichomonas vaginalis PIKK family atypical protein kinase 0.0523 0.0884 0.5861
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0003 0.0003
Brugia malayi follicle stimulating hormone receptor 0.0251 0.0413 0.2737
Trichomonas vaginalis conserved hypothetical protein 0.0012 0 0.0000039333
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0002 0.0011
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0015 0.0015
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0037 0.0183
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0012
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0015 0.0015
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0884 0.1509 1
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0212 0.0346 0.2294
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0073 0.0106 0.0465
Trypanosoma cruzi FHA domain containing protein, putative 0.0019 0.0013 0.0037
Trypanosoma cruzi histone deacetylase, putative 0.0351 0.0588 0.1698
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0012 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0029
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0332 0.0554 0.3672
Trypanosoma cruzi histone deacetylase 1, putative 0.0881 0.1503 0.4345
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0015 0.0015
Plasmodium falciparum histone deacetylase, putative 0.0678 0.1152 0.7665
Trichomonas vaginalis histone deacetylase, putative 0.0881 0.1503 0.9964
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0135
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0012 0.0012
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0065 0.0091 0.0605
Echinococcus multilocularis casein kinase ii subunit alpha 0.0145 0.0231 0.0231
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0034 0.0038 0.0038
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0552 0.0934 0.0934
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0002 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0518 0.0876 0.5803
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0115 0.0179 0.972
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0065 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0499 0.0844 0.4153
Trypanosoma brucei histone deacetylase 1 0.0881 0.1503 1
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0 0.0001
Brugia malayi hypothetical protein 0.0173 0.0279 0.1847
Loa Loa (eye worm) hypothetical protein 0.0191 0.0309 0.1521
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0039 0.0047 0.0134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0562 0.0952 0.6307
Echinococcus granulosus histone deacetylase 6 0.0678 0.1152 0.1152
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0091 0.0605
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0542 0.0918 0.2505
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0019 0.0597
Trichomonas vaginalis CAMK family protein kinase 0.0203 0.0331 0.2194
Onchocerca volvulus 0.0073 0.0106 0.1293
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0002 0.0014
Brugia malayi RNA binding protein 0.0126 0.0197 0.1303
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0179 0.1185
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0037 0.1916
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0091 0.0605
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0071
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0012 0.0078
Brugia malayi Histone deacetylase family protein 0.0678 0.1152 0.7638
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0037 0.0108
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0736 0.1253 0.8303
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0205 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0045
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.036 0.0602 0.4006
Brugia malayi CHD4 protein 0.0012 0 0.00000000004382
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0106 0.0462
Schistosoma mansoni brca1-associated protein (brap2) 0.0013 0.0002 0.001
Entamoeba histolytica protein kinase domain containing protein 0.0054 0.0073 0.0482
Echinococcus granulosus casein kinase ii subunit alpha 0.0145 0.0231 0.0231
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0115 0.0179 0.9712
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0047 0.0308
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0091 0.0605
Trichomonas vaginalis PIKK family atypical protein kinase 0.0309 0.0514 0.3403
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0145 0.0231 0.0231
Toxoplasma gondii Zn-finger in ubiquitin-hydrolases domain-containing protein 0.0013 0.0002 0.0014
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.0149 0.0734
Schistosoma mansoni DNA polymerase eta 0.0019 0.0012 0.0052
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0024 0.0021 0.0137
Mycobacterium leprae conserved hypothetical protein 0.0118 0.0184 1
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0157 0.0251 0.1671
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0016
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0015 0.0006 0.0025
Loa Loa (eye worm) hypothetical protein 0.0297 0.0493 0.2428
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0019 0.0667
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0037 0.0183
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0046 0.0059 0.0393
Treponema pallidum DNA ligase (lig) 0.0019 0.0013 0.0112
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0012 0.0078
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0047 0.0308
Brugia malayi hypothetical protein 0.0073 0.0106 0.07
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0004 0.0018
Brugia malayi FAT domain containing protein 0.0205 0.0335 0.2218
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0884 0.1509 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0091 0.0605
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0015 0.0064
Loa Loa (eye worm) hypothetical protein 0.0023 0.002 0.0097
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0033 0.1326
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0016
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0118 0.0184 0.1223
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0305 0.0506 0.3356
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0118 0.0184 0.1223
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0118 0.0184 0.1218
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0065 0.0091 0.0605
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0012 0.0034
Trichomonas vaginalis CMGC family protein kinase 0.0145 0.0231 0.1528
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0019 0.0013 0.0085
Trichomonas vaginalis CMGC family protein kinase 0.0145 0.0231 0.1528
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0012 0.0012
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0091 0.0605
Leishmania major ATP-dependent phosphofructokinase 0.0115 0.0179 0.0488
Loa Loa (eye worm) hypothetical protein 0.0071 0.0103 0.0507
Echinococcus granulosus pyruvate kinase 0.0017 0.0009 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0086 0.0374
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0047 0.0308
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0562 0.0952 0.4161
Loa Loa (eye worm) RNA binding protein 0.0126 0.0197 0.0968
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0009 0.006
Echinococcus multilocularis pyruvate kinase 0.0017 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0085
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0013 0.0002 0.0006
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.0033 0.0037 0.0183
Entamoeba histolytica hypothetical protein 0.0736 0.1253 0.8303
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0019 0.0013 0.0214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0518 0.0876 0.5803
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0013 0.0085
Echinococcus multilocularis histone deacetylase 3 0.0881 0.1503 0.1503
Onchocerca volvulus 0.0052 0.007 0.0853
Echinococcus multilocularis cyclin dependent kinase 19 0.0142 0.0225 0.0225
Loa Loa (eye worm) RecQ helicase 0.0022 0.0018 0.0089
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0015 0.0096
Schistosoma mansoni hypothetical protein 0.0205 0.0335 0.1463
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0009 0.1929
Plasmodium falciparum casein kinase II beta chain 0.0039 0.0047 0.0309
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0054 0.0073 0.0199
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0015 0.0071
Schistosoma mansoni DNA ligase IV 0.0019 0.0013 0.0056
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0439 0.0739 0.4896
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0024 0.0021 0.0102
Echinococcus granulosus pyruvate kinase 0.0033 0.0037 0.0037
Trichomonas vaginalis histone deacetylase, putative 0.0881 0.1503 0.9964
Echinococcus multilocularis nibrin 0.0019 0.0013 0.0013
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0054 0.0073 0.021
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0118 0.0184 0.1218
Brugia malayi M-phase phosphoprotein, mpp8 0.0107 0.0164 0.1084
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0021 0.0015 0.034
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0039 0.0047 0.0309
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0118 0.0184 0.0804
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0034 0.0038 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0542 0.0918 0.6083
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0039 0.0047 0.0567
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0212 0.0346 0.1001
Trichomonas vaginalis chromobox protein, putative 0.0012 0 0.0000039333
Brugia malayi RNA recognition motif domain containing protein 0.0126 0.0197 0.1303
Echinococcus granulosus serine protein kinase ATM 0.0309 0.0514 0.0514
Echinococcus multilocularis dna polymerase eta 0.0019 0.0012 0.0012
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0015 0.0096
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0054 0.0073 0.0358
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0017 0.0009 0.0025
Trypanosoma brucei histone deacetylase 2 0.0351 0.0588 0.3908
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0004 0.0018
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0009 0.006
Echinococcus granulosus death domain containing protein 0.0015 0.0006 0.0006
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0003 0.0003
Plasmodium falciparum glycogen synthase kinase 3 0.0054 0.0073 0.0484
Trichomonas vaginalis chromobox protein, putative 0.0012 0 0.0000039333
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0011 0.0072
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0011 0.0031
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.036 0.0602 0.3991
Onchocerca volvulus 0.0107 0.0164 0.1991
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0091 0.0605
Loa Loa (eye worm) phosphatidylinositol 3 0.051 0.0862 0.4242
Echinococcus granulosus bloom syndrome protein 0.0022 0.0018 0.0018
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0212 0.0346 0.0346
Plasmodium vivax hypothetical protein, conserved 0.0118 0.0184 0.1223
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0012 0.0078
Echinococcus granulosus beta-adrenergic receptor kinase 0.0024 0.0021 0.0021
Leishmania major hypothetical protein, conserved 0.0013 0.0002 0.0006
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0045 0.0045
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0021 0.0015 0.042
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0037 0.0108
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0019 0.0013 0.0085
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0039 0.0047 0.0308
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0012 0.0012
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0179 0.1185
Toxoplasma gondii ck2 beta subunit 0.0039 0.0047 0.0309
Brugia malayi 6-phosphofructokinase 0.0115 0.0179 0.1184
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0095 0.0143 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0537 0.0909 0.6027
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0012 0.0238
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0037 0.1684
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0003 0.0007
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1334 0.2287 0.2287
Schistosoma mansoni hypothetical protein 0.0039 0.0047 0.0207
Echinococcus granulosus high voltage activated calcium channel beta 0.0092 0.0139 0.0139
Trypanosoma cruzi casein kinase II, putative 0.0145 0.0231 0.0666
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0039 0.0047 0.0309
Giardia lamblia Kinase, CMGC GSK 0.0054 0.0073 0.047
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0309 0.0514 0.3403
Loa Loa (eye worm) gastrulation defective protein 1 0.0138 0.0219 0.1076
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0065 0.0091 0.0264
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0029 0.0029 0.0029
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0045 0.03
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0019 0.0013 1
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0003 0.0003
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0017 0.0009 0.0025
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0039 0.0047 0.0134
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0065 0.0091 0.0607
Brugia malayi Protein kinase domain containing protein 0.0019 0.0012 0.0078
Entamoeba histolytica hypothetical protein 0.002 0.0015 0.0096
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0039 0.0047 0.0127
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0065 0.0091 0.0264
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0019 0.0597
Plasmodium vivax casein kinase II beta chain, putative 0.0039 0.0047 0.0309
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0428 0.072 0.3543
Toxoplasma gondii TIM10 family protein, putative 0.0046 0.0059 0.0395
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0019 0.0053
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0015 0.0006 0.0027
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0012 0.0078
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0015 0.0096
Brugia malayi C1-like domain containing protein 0.0013 0.0003 0.0016
Echinococcus granulosus single minded 2 0.0038 0.0045 0.0045
Entamoeba histolytica hypothetical protein 0.0012 0 0.0000039333
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0047 0.0308
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0015 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0012 0 0.0000039333
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0019 0.0928
Echinococcus multilocularis histone deacetylase 1 0.0881 0.1503 0.1503
Loa Loa (eye worm) histone deacetylase 3 0.0881 0.1503 0.7401
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0145 0.0231 0.1011
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0033 0.0033
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0058 0.0058
Toxoplasma gondii exonuclease III APE 0.0018 0.0011 0.0072
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0015 0.0006 0.0006
Trypanosoma cruzi histone deacetylase, putative 0.0678 0.1152 0.3331
Echinococcus multilocularis geminin 0.0677 0.1151 0.1151
Echinococcus granulosus histone deacetylase 1 0.0881 0.1503 0.1503
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0028 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0012 0 0.0000039333
Trichomonas vaginalis PIKK family atypical protein kinase 0.0562 0.0952 0.6307
Loa Loa (eye worm) hypothetical protein 0.0107 0.0164 0.0807
Trichomonas vaginalis PIKK family atypical protein kinase 0.0118 0.0184 0.1218
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.0092 0.0139 0.0606
Loa Loa (eye worm) hypothetical protein 0.0118 0.0184 0.0905
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0562 0.0952 0.633
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0012 0 0.000000000043978
Trypanosoma brucei cytochrome P450, putative 0.0021 0.0015 0.0099
Plasmodium falciparum pyruvate kinase 0.0033 0.0037 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0091 0.0605
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0015 0.0015
Echinococcus multilocularis expressed conserved protein 0.0086 0.0129 0.0129
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0341 0.0569 0.0569
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0012 0.0034
Entamoeba histolytica protein kinase rad3, putative 0.0293 0.0487 0.3225
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0029 0.0029 0.0126
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0006 0.0026
Loa Loa (eye worm) TAR-binding protein 0.0126 0.0197 0.0968
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0012 0.0078
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0015 0.0096
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0034 0.0038 0.0167
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.0002 0.0014
Schistosoma mansoni lamin 0.0028 0.0028 0.0124
Schistosoma mansoni hypothetical protein 0.0118 0.0184 0.0804
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0037 0.0246
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0884 0.1509 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0 0.0000039333
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0095 0.0143 0.0625
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0562 0.0952 0.0952
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0212 0.0346 0.0945
Trichomonas vaginalis chromobox protein, putative 0.0012 0 0.0000039333
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0552 0.0934 0.4085
Brugia malayi hypothetical protein 0.0035 0.0041 0.0269
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0086 0.0086
Schistosoma mansoni tar DNA-binding protein 0.0126 0.0197 0.086
Echinococcus granulosus histone deacetylase 3 0.0881 0.1503 0.1503
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0013 0.0003 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0086 0.0374
Entamoeba histolytica hypothetical protein 0.002 0.0015 0.0096
Toxoplasma gondii hypothetical protein 0.0057 0.0078 0.0515
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0003 0.0012
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0047 0.0308
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0047 0.0308
Brugia malayi Death domain containing protein 0.0015 0.0006 0.0037
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0009 0.006
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0033 0.022
Echinococcus multilocularis expressed protein 0.0046 0.0059 0.0059
Brugia malayi Protein kinase domain containing protein 0.0142 0.0225 0.149
Schistosoma mansoni histone deacetylase hda2 0.0351 0.0588 0.2569
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0091 0.0605
Echinococcus granulosus intermediate filament protein 0.0028 0.0028 0.0028
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0046 0.0059 0.0395
Schistosoma mansoni histone deacetylase hda2 0.0691 0.1175 0.5139
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0003 0.0007
Echinococcus granulosus Ankyrin 0.0015 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0085
Trichomonas vaginalis chromobox protein, putative 0.0012 0 0.0000039333
Echinococcus granulosus expressed protein 0.0046 0.0059 0.0059
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0019 0.0928
Leishmania major DNA polymerase kappa, putative 0.0019 0.0012 0.0032
Schistosoma mansoni casein kinase II beta subunit 0.0039 0.0047 0.0204
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0118 0.0184 0.1223
Trichomonas vaginalis set domain proteins, putative 0.0487 0.0822 0.5448
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0562 0.0952 0.2597
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0006 0.0037
Echinococcus multilocularis lamin 0.0028 0.0028 0.0028
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0062 0.0086 0.0423
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0063
Schistosoma mansoni hypothetical protein 0.0031 0.0033 0.0145
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0881 0.1503 0.9964
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0019 0.0597
Schistosoma mansoni histone deacetylase 0.0881 0.1503 0.6573
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0063
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0012 0.0058
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0212 0.0346 0.2303
Trichomonas vaginalis conserved hypothetical protein 0.0012 0 0.0000039333
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0156 0.1034
Trypanosoma cruzi polo-like protein kinase, putative 0.0203 0.0331 0.0957
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0552 0.0934 0.27
Trypanosoma brucei protein kinase, putative 0.0054 0.0073 0.0484
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0034 0.0038 0.0252
Trypanosoma brucei Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0013 0.0002 0.0014
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0635 0.1078 0.1078
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0011 0.0102
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0118 0.0184 0.1223
Entamoeba histolytica casein kinase, putative 0.0145 0.0231 0.1528
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0071
Loa Loa (eye worm) hypothetical protein 0.0012 0 0.000000000032549
Toxoplasma gondii GAF domain-containing protein 0.0021 0.0015 0.0099
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0034 0.0038 0.0038
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0017 0.0009 0.0025
Onchocerca volvulus 0.0102 0.0156 0.1893
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0015 0.0015
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0013 0.0002 0.0002
Plasmodium vivax casein kinase II beta chain, putative 0.0039 0.0047 0.0309
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0033 0.022
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0179 0.1185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0518 0.0876 0.5803
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1334 0.2287 0.2287
Echinococcus granulosus voltage dependent calcium channel 0.0034 0.0038 0.0038
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0006 0.0027
Brugia malayi Serotonin receptor 0.0495 0.0835 0.5535
Echinococcus granulosus pyruvate kinase 0.0017 0.0009 0.0009
Loa Loa (eye worm) histone deacetylase 11 0.0351 0.0588 0.2893
Echinococcus multilocularis GPCR, family 2 0.0031 0.0033 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0518 0.0876 0.5804
Mycobacterium ulcerans 6-phosphofructokinase 0.0115 0.0179 1
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0029 0.0029 0.0029
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0179 0.088
Brugia malayi hypothetical protein 0.0035 0.0041 0.0269
Schistosoma mansoni vav2 0.0015 0.0006 0.0024
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0021 0.0015 0.0334
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0047 0.0308
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0037 0.0247
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0046 0.0059 0.0292
Plasmodium vivax histone deacetylase, putative 0.0678 0.1152 0.7665
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0118 0.0184 0.0184
Loa Loa (eye worm) hypoxia-induced factor 1 0.016 0.0256 0.1258
Brugia malayi PXA domain containing protein 0.0022 0.0017 0.0113
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0015 0.0073
Leishmania major casein kinase II, putative 0.0145 0.0231 0.0629
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0019 0.0597
Toxoplasma gondii CMGC kinase, CK2 family 0.0145 0.0231 0.1534
Loa Loa (eye worm) hypothetical protein 0.0107 0.0164 0.0805
Loa Loa (eye worm) phosphatidylinositol 3 0.0242 0.0398 0.1958
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0012 0.0151
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0063
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0013 0.0002 0.0002
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0151 0.0241 0.1187
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0212 0.0346 0.2303
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0058 0.0255
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0 0.0000039333
Leishmania major hypothetical protein, conserved 0.2129 0.3664 1
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0013 0.0002 0.0002
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.036 0.0602 0.3991
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0039 0.0047 0.0308
Echinococcus multilocularis survival motor neuron protein 1 0.0499 0.0844 0.0844
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0065 0.0091 0.0605
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0058 0.0255
Brugia malayi intermediate filament protein 0.0028 0.0028 0.0188
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0009 0.0093
Echinococcus multilocularis Ankyrin 0.0015 0.0006 0.0006
Plasmodium vivax histone deacetylase, putative 0.0351 0.0588 0.3908
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0053 0.0354
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0343 0.0573 0.3811
Schistosoma mansoni serine/threonine protein kinase 0.0341 0.0569 0.2487
Entamoeba histolytica hypothetical protein 0.0073 0.0106 0.07
Schistosoma mansoni regulator of G protein signaling 0.002 0.0015 0.0064
Onchocerca volvulus 0.0038 0.0045 0.0553
Leishmania major phosphatidylinositol 3-kinase, putative 0.0498 0.0842 0.2298
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0224 0.0224
Echinococcus granulosus lamin 0.0028 0.0028 0.0028
Entamoeba histolytica hypothetical protein 0.002 0.0015 0.0096
Echinococcus multilocularis pyruvate kinase 0.0033 0.0037 0.0037
Schistosoma mansoni fkbp-rapamycin associated protein 0.0293 0.0487 0.2128
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.0002 0.0014
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0657 0.1116 0.7398
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0179 0.088
Schistosoma mansoni tar DNA-binding protein 0.0126 0.0197 0.086
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0011 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0012 0.0078
Echinococcus multilocularis musashi 0.0028 0.0028 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0012 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0332 0.0554 0.3672
Trichomonas vaginalis PIKK family atypical protein kinase 0.0542 0.0918 0.6083
Onchocerca volvulus 0.0487 0.0822 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0033 0.0033
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0015 0.0015
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0046 0.0059 0.0395
Onchocerca volvulus 0.0019 0.0013 0.0157
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0047 0.0312
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0015 0.0099
Onchocerca volvulus 0.0013 0.0003 0.0031
Echinococcus granulosus GPCR family 2 0.0031 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0002 0.0011
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0091 0.0605
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0293 0.0487 0.3225
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0039 0.0047 0.0314
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.007 0.0307
Leishmania major histone deacetylase, putative 0.0881 0.1503 0.4103
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0013 0.0037
Echinococcus granulosus BRCA1 associated protein 0.0013 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0012 0 0.0000039333
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0051 0.0067 0.0329
Loa Loa (eye worm) hypothetical protein 0.0635 0.1078 0.5308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0518 0.0876 0.5804
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0118 0.0184 0.1223
Schistosoma mansoni lamin 0.0028 0.0028 0.0124
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0003 0.0007
Echinococcus multilocularis histone deacetylase 6 0.0691 0.1175 0.1175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0542 0.0918 0.6083
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0086 0.0086
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0039 0.0047 0.0314
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0046 0.0059 0.026
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0091 0.0605
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0058 0.0058
Toxoplasma gondii histone deacetylase HDAC1 0.0678 0.1152 0.7665
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0029 0.0029 0.019
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0118 0.0184 0.1223
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0 0.0001
Echinococcus multilocularis N chimaerin 0.0015 0.0006 0.0006
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0086 0.0086
Mycobacterium tuberculosis Conserved hypothetical protein 0.0118 0.0184 1
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0037 0.0247
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0015 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0537 0.0909 0.6027
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0011 0.0072
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0179 0.1185
Schistosoma mansoni serine/threonine protein kinase 0.0203 0.0331 0.1448
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0013 0.0002 0.0014
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0003 0.0016
Brugia malayi Pre-SET motif family protein 0.0061 0.0086 0.0566
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0045 0.2133
Leishmania major hypothetical protein, unknown function 0.0118 0.0184 0.0502
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0015 0.0096
Brugia malayi protein kinase C II. 0.0014 0.0004 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.0203 0.0331 0.2194
Chlamydia trachomatis pyruvate kinase 0.0033 0.0037 1
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0013 0.0037
Trypanosoma cruzi polo-like protein kinase, putative 0.0203 0.0331 0.0957
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0013 0.0089
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0637 0.1082 0.7174
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0012 0.0052
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0203 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0881 0.1503 0.7401
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.005
Loa Loa (eye worm) histone deacetylase 7A 0.0678 0.1152 0.5673
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0537 0.0909 0.6027
Echinococcus multilocularis expressed protein 0.0396 0.0664 0.0664
Echinococcus multilocularis tar DNA binding protein 0.0126 0.0197 0.0197
Schistosoma mansoni chromosome transmission fidelity factor 0.0019 0.0013 0.0056
Leishmania major pyruvate kinase 0.0033 0.0037 0.0102
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0 0.0000039333
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0012 0.0078
Giardia lamblia Pyruvate kinase 0.0017 0.0009 0.0045
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0039 0.0047 0.0313
Schistosoma mansoni ap endonuclease 0.0018 0.0011 0.0048
Trichomonas vaginalis CAMK family protein kinase 0.0203 0.0331 0.2194
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0006 0.0028
Schistosoma mansoni intermediate filament proteins 0.0028 0.0028 0.0124
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0029 0.0029 0.019
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0018 0.012
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0015 0.0006 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0179 0.1185
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0034 0.0038 0.0038
Echinococcus multilocularis Rac GTPase activating protein 1 0.0071 0.0103 0.0103
Onchocerca volvulus 0.0028 0.0028 0.0346
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0013 0.0002 0.0006
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0015 0.0099
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0044 0.0056 0.0161
Trichomonas vaginalis CAMK family protein kinase 0.0203 0.0331 0.2194
Schistosoma mansoni axis inhibition protein axin 0.002 0.0015 0.0064
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.036 0.0602 0.1741
Trichomonas vaginalis CAMK family protein kinase 0.0203 0.0331 0.2194
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0013 0.0003 0.0016
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0091 0.0605
Trypanosoma cruzi histone deacetylase, putative 0.0678 0.1152 0.3331
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0006 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0012 0 0.0000039333
Brugia malayi Cytochrome P450 family protein 0.0021 0.0015 0.0098
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0021 0.0091
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0 0.0000039333
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0003 0.0016
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0091 0.0605
Echinococcus multilocularis voltage dependent calcium channel 0.0034 0.0038 0.0038
Schistosoma mansoni hypothetical protein 0.0067 0.0095 0.0417
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0054 0.0073 0.0073
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0 0.0000039333
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0033 0.0206
Trichomonas vaginalis PIKK family atypical protein kinase 0.0367 0.0615 0.4076
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0033 0.8832
Schistosoma mansoni protein kinase 0.0145 0.0231 0.1008
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0047 0.0308
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0046 0.0059 0.0395
Echinococcus granulosus protein kinase c iota type 0.0013 0.0003 0.0003
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0047 0.0308
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0212 0.0346 0.1704
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0095 0.0143 0.0143
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0012 0.0078
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0033 0.022
Loa Loa (eye worm) phosphatidylinositol 3 0.0118 0.0184 0.0905
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0562 0.0952 0.2597
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0118 0.0184 0.1223
Onchocerca volvulus 0.0118 0.0184 0.2237
Echinococcus granulosus dna polymerase eta 0.0019 0.0012 0.0012
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0091 0.0605
Toxoplasma gondii histone deacetylase HDAC5 0.0352 0.0588 0.391
Entamoeba histolytica protein kinase domain containing protein 0.0145 0.0231 0.1528
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0018 0.012
Schistosoma mansoni histone deacetylase 1 2 3 0.0351 0.0588 0.2569
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0053 0.0353
Brugia malayi hypothetical protein 0.0019 0.0013 0.0085
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.002 0.013
Trichomonas vaginalis CMGC family protein kinase 0.0145 0.0231 0.1528
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0635 0.1078 0.1078
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0 0.0000039333
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0 0.0000039333
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.051 0.0862 0.5731
Echinococcus granulosus cyclin dependent kinase 19 0.0142 0.0225 0.0225
Trichomonas vaginalis casein kinase II beta chain, putative 0.0039 0.0047 0.0308
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0 0.0000039333
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0212 0.0346 0.1514
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0044 0.0056 0.0368
Toxoplasma gondii target of rapamycin (TOR), putative 0.0537 0.0909 0.6049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0542 0.0918 0.6083
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0 0.0000039333
Schistosoma mansoni brca1-associated protein (brap2) 0.0013 0.0002 0.001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0332 0.0554 0.3672
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0881 0.1503 0.9964
Loa Loa (eye worm) hypothetical protein 0.0019 0.0013 0.0063
Loa Loa (eye worm) hypothetical protein 0.0098 0.0149 0.0734
Trichomonas vaginalis replication factor C large subunit, putative 0.0019 0.0013 0.0085
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0013 0.0003 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0012 0 0.0000039333
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0003 0.0016
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0034 0.0166
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0884 0.1509 0.4361
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0019 0.0597
Schistosoma mansoni histone deacetylase 4 5 0.0678 0.1152 0.5039
Giardia lamblia Kinase, CMGC CK2 0.0145 0.0231 0.1521
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0012 0.0151
Echinococcus granulosus histone deacetylase 6 0.0678 0.1152 0.1152
Toxoplasma gondii histone deacetylase HDAC4 0.0351 0.0588 0.3908
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0013 0.0003 0.0003
Giardia lamblia Rho GAP, putative 0.0062 0.0086 0.0558
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0552 0.0934 0.27
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0037 0.0454
Brugia malayi SET domain containing protein 0.0014 0.0004 0.0026
Echinococcus multilocularis lamin dm0 0.0028 0.0028 0.0028
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0037 0.0247
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0019 0.0128
Schistosoma mansoni histone deacetylase 4 5 0.0678 0.1152 0.5039
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0091 0.0605
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0053 0.0053
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0065 0.0091 0.0264
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0015 0.0015
Trichomonas vaginalis CMGC family protein kinase 0.0145 0.0231 0.1528
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0012 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0498 0.0842 0.558
Toxoplasma gondii histone deacetylase HDAC3 0.0881 0.1503 1
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0033 0.022
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0003 0.0016
Brugia malayi histone deacetylase 11 0.0351 0.0588 0.3894

Activities

Activity type Activity value Assay description Source Reference
Delta blood pressure (functional) = 40 mM Compound was tested for bradykinin potentiation at 0.1 ug/kg dose ChEMBL. 2832605
Delta blood pressure (functional) = 40 mM Compound was tested for bradykinin potentiation at 0.1 ug/kg dose ChEMBL. 2832605
ID50 (binding) z 0 ug kg-1 In vivo inhibition of Angiotensin I converting enzyme at 1000microg/Kg in anaestatized rats.;z denotes 'Inactive' ChEMBL. 2832605
ID50 (binding) = 0.56 ug kg-1 In vitro inhibition of Angiotensin I converting enzyme relative to captopril(=1) ChEMBL. 2832605
ID50 (binding) = 0.56 ug kg-1 In vitro inhibition of Angiotensin I converting enzyme relative to captopril(=1) ChEMBL. 2832605

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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