Detailed information for compound 331032

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 322.321 | Formula: C16H14N6O2
  • H donors: 1 H acceptors: 4 LogP: 1.71 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCn1c(nc2c1ccnc2Oc1ccccc1)c1nonc1N
  • InChi: 1S/C16H14N6O2/c1-2-22-11-8-9-18-16(23-10-6-4-3-5-7-10)12(11)19-15(22)13-14(17)21-24-20-13/h3-9H,2H2,1H3,(H2,17,21)
  • InChiKey: IDWNTTNNMPLDJW-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 5 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis serine/threonine-protein kinase, putative Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Babesia bovis cAMP-dependent protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Loa Loa (eye worm) AGC/RSK/MSK protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
Trichomonas vaginalis AGC family protein kinase Get druggable targets OG5_128437 All targets in OG5_128437
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis geminin 0.0169 0.0634 0.0736
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0115 0.0409
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.1157 1
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0066 0.0091
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0066 0.0091
Schistosoma mansoni DNA helicase recq1 0.0051 0.015 0.0174
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0018 0.0018 0.0094
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.021 0.0243
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0015 0.0151
Echinococcus multilocularis polycomb protein SCMH1 0.0099 0.0349 0.0405
Brugia malayi Bromodomain containing protein 0.0043 0.0116 0.016
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0018 0.0065
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0101 0.0117
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.001 0.0017
Trichomonas vaginalis DNA polymerase eta, putative 0.0126 0.0458 0.3904
Onchocerca volvulus Serine\/threonine kinase homolog 0.0102 0.0361 0.0361
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0002
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0066 0.0076
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.002 0.0049
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0022 0.006
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0101 1
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0079 0.1247
Echinococcus multilocularis protein kinase c epsilon type 0.0018 0.0018 0.002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0045 0.0299
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0458 0.1685
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0126 0.0458 0.3904
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0002
Schistosoma mansoni chromobox protein 0.0071 0.0232 0.0269
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0044 0.0124 0.0143
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0066 0.0076
Loa Loa (eye worm) BRM protein 0.0074 0.0246 0.1306
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0051 0.015 0.0207
Entamoeba histolytica hypothetical protein 0.0023 0.0037 0.0062
Schistosoma mansoni inositol monophosphatase 0.0037 0.0096 0.0111
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0113 0.0406 0.0471
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0104
Schistosoma mansoni Mername-AA248 (C02 family) 0.0019 0.0022 0.0025
Brugia malayi Disco-interacting protein 2 homolog 0.0038 0.0099 0.0137
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0022 0.006
Echinococcus granulosus Protein kinase C brain isozyme 0.0018 0.0018 0.002
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0047 0.0054
Brugia malayi serine/threonine-protein kinase plk-2 0.0102 0.0361 0.0498
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0022 0.006
Echinococcus granulosus protein kinase C gamma type 0.0018 0.0018 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0066 0.035
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0166 0.0621 0.0721
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0193 0.0733 0.0732
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0063 0.0336
Brugia malayi Protein kinase domain containing protein 0.0018 0.0018 0.0024
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.006 0.0202
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0066 0.0065
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0051 0.015 0.0174
Plasmodium vivax SET domain protein, putative 0.0033 0.0076 0.026
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0066 0.0076
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.1157 1
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0018 0.0065
Loa Loa (eye worm) DR-78 0.0014 0 0.0002
Echinococcus multilocularis DNA repair protein complementing XP G cells 0.0017 0.001 0.0011
Leishmania major kinesin, putative 0.0019 0.0022 0.006
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0018 0.0018 0.002
Onchocerca volvulus 0.0243 0.0937 0.0936
Loa Loa (eye worm) hypothetical protein 0.0039 0.0102 0.054
Echinococcus granulosus polycomb protein SCMH1 0.0099 0.0349 0.0405
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0051 0.015 0.0798
Echinococcus granulosus snurportin 1 0.0307 0.1199 0.1392
Schistosoma mansoni jun-related protein 0.0135 0.0494 0.0573
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0047 0.0249
Entamoeba histolytica protein kinase, putative 0.0018 0.0018 0.0017
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0076 0.026
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0102 0.0361 0.0419
Brugia malayi ecdysteroid receptor 0.003 0.0066 0.0091
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0232 0.1931
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0101 0.0793
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0002
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0063 0.0337
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0159 0.057
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0022 0.006
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0007 0.0007
Echinococcus multilocularis Protein lozenge 0.0059 0.0185 0.0215
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0096 0.0744
Brugia malayi nuclear receptor RXR 0.0016 0.0007 0.001
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0113 0.0406 0.0471
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0012 0.0013
Echinococcus granulosus cpg binding protein 0.0098 0.0344 0.0399
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0246 0.0895
Loa Loa (eye worm) hypothetical protein 0.0193 0.0733 0.3893
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0007 0.0008
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0012 0.0013
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0002
Brugia malayi PHD-finger family protein 0.0015 0.0003 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.0011 0.0013
Echinococcus multilocularis Smad4 0.0026 0.0047 0.0054
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.004
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0063 0.0087
Schistosoma mansoni hypothetical protein 0.0307 0.1199 0.1392
Loa Loa (eye worm) hypothetical protein 0.003 0.0066 0.035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.1157 1
Echinococcus granulosus SAM and MBT domain containing protein 0.0099 0.0349 0.0405
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0006
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0145 0.0536 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0045 0.0299
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0101 0.0206
Brugia malayi ecdysone receptor 0.0014 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.046 0.1827 0.9708
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0361 0.0419
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0007 0.0003
Brugia malayi Protein kinase domain containing protein 0.0018 0.0018 0.0024
Brugia malayi calpain family protein 1 0.0065 0.021 0.0289
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0066 0.0091
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0018
Echinococcus granulosus exonuclease 1 0.0017 0.001 0.0011
Schistosoma mansoni blooms syndrome DNA helicase 0.0026 0.0048 0.0055
Giardia lamblia Flap structure-specific endonuclease 0.0082 0.0278 0.0606
Onchocerca volvulus 0.0055 0.0169 0.0168
Echinococcus granulosus global transcription activator snf2l2 0.0141 0.052 0.0604
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0082 0.0278 0.1014
Schistosoma mansoni hypothetical protein 0.0169 0.0634 0.0736
Loa Loa (eye worm) BRM protein 0.0089 0.0305 0.162
Trichomonas vaginalis AGC family protein kinase 0.0043 0.0118 0.0942
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0486 0.0564
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0066 0.0076
Brugia malayi calpain 5 0.0019 0.0022 0.003
Echinococcus multilocularis chromobox protein 1 0.0071 0.0232 0.0269
Brugia malayi isocitrate dehydrogenase 0.0016 0.0007 0.0009
Loa Loa (eye worm) helicase DNA-binding protein 0.0024 0.004 0.0215
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0159 0.057
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0097 0.034 0.1808
Brugia malayi Smad1 0.0026 0.0047 0.0065
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0066 0.0076
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0066 0.0076
Schistosoma mansoni terminal deoxycytidyl transferase 0.0097 0.034 0.0395
Echinococcus multilocularis flap endonuclease GEN 1 0.0017 0.001 0.0011
Brugia malayi latrophilin 2 splice variant baaae 0.0141 0.0521 0.0718
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0169 0.0232
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0066 0.0076
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.006 0.0186 0.0672
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.1157 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0007 0.0007
Echinococcus multilocularis serine threonine protein kinase 0.0018 0.0018 0.002
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0101 0.0538
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.001 0.0017
Brugia malayi conserved hypotetical protein 0.0014 0 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0516 0.0599
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0101 0.0356
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0101 0.0356
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0 0.0002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0126 0.0458 0.1685
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0046 0.015
Brugia malayi calpain family protein 1 0.0065 0.021 0.0289
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.0048 0.0158
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family member 0.0017 0.001 0.0011
Giardia lamblia Telomerase catalytic subunit 0.0671 0.2689 0.6072
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family 0.0017 0.001 0.0011
Schistosoma mansoni cpg binding protein 0.0098 0.0344 0.0399
Loa Loa (eye worm) RecQ helicase 0.0093 0.0323 0.1716
Echinococcus multilocularis BRK domain containing protein 0.0024 0.004 0.0046
Trichomonas vaginalis AGC family protein kinase 0.0043 0.0118 0.0942
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0361 0.3059
Echinococcus granulosus geminin 0.0169 0.0634 0.0736
Loa Loa (eye worm) hypothetical protein 0.0207 0.0789 0.419
Plasmodium falciparum DEAD/DEAH box helicase, putative 0.0022 0.003 0.0089
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.005 0.0057
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0015 0.0003 0.0003
Echinococcus granulosus histone acetyltransferase MYST2 0.0113 0.0406 0.0471
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0066 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0066 0.0091
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0054 0.0175
Schistosoma mansoni hypothetical protein 0.0065 0.021 0.0243
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0458 0.1685
Schistosoma mansoni helicase 0.0141 0.052 0.0604
Schistosoma mansoni chromobox protein 0.0071 0.0232 0.0269
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0002
Toxoplasma gondii AGC kinase 0.0018 0.0018 0.0042
Schistosoma mansoni thyroid hormone receptor 0.003 0.0066 0.0076
Echinococcus multilocularis hypothetical protein 0.0019 0.0022 0.0025
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.1157 1
Echinococcus multilocularis calpain 7 (C02 family) 0.0019 0.0022 0.0025
Brugia malayi steroid hormone receptor 0.003 0.0066 0.0091
Plasmodium falciparum telomerase reverse transcriptase 0.0671 0.2689 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0091 0.0106
Brugia malayi nuclear receptor NHR-88 0.003 0.0066 0.0091
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0159 0.0336
Brugia malayi RNA, U transporter 1 0.0082 0.0277 0.0382
Echinococcus multilocularis bloom syndrome protein 0.0093 0.0323 0.0375
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0046 0.0081
Entamoeba histolytica Flap nuclease, putative 0.0082 0.0278 0.0606
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0066 0.0076
Leishmania major DNA polymerase kappa, putative 0.003 0.0066 0.0224
Echinococcus multilocularis neuropeptide receptor A26 0.0494 0.1967 0.2285
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.1157 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0012 0.0013
Echinococcus multilocularis chromodomain helicase DNA binding protein 7 0.0024 0.004 0.0046
Mycobacterium ulcerans DNA polymerase IV 0.0126 0.0458 0.4221
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0066 0.0224
Loa Loa (eye worm) hypothetical protein 0.0029 0.006 0.0317
Giardia lamblia DINP protein human, muc B family 0.0104 0.0369 0.0814
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0007 0.0008
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0063 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0066 0.0091
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0046 0.0063
Brugia malayi MH2 domain containing protein 0.0376 0.1481 0.2041
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0007 0.0008
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0232 0.1931
Echinococcus multilocularis dnaJ subfamily B 0.0845 0.3403 0.3954
Echinococcus granulosus lysine specific demethylase 5A 0.0041 0.0111 0.0128
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0066 0.0224
Loa Loa (eye worm) calpain family protein 1 0.0046 0.013 0.0692
Echinococcus granulosus jun protein 0.0166 0.0621 0.0721
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0077 0.0255 0.1357
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.0525 0.1937
Brugia malayi glutaminase DH11.1 0.0272 0.1058 0.1459
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0104 0.0369 0.6204
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0111 0.0128
Treponema pallidum fructose-bisphosphate aldolase 0.0297 0.1157 1
Schistosoma mansoni hypothetical protein 0.0036 0.0088 0.0101
Schistosoma mansoni cpg binding protein 0.0098 0.0344 0.0399
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.014 0.0516 0.0712
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0015 0.0151
Schistosoma mansoni atypical protein kinase C 0.0018 0.0018 0.002
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0066 0.0224
Plasmodium vivax DEAD/DEAH helicase, putative 0.0022 0.003 0.0089
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0104
Echinococcus granulosus dna polymerase eta 0.0125 0.0453 0.0526
Onchocerca volvulus 0.0031 0.0069 0.0069
Plasmodium vivax telomerase reverse transcriptase, putative 0.0671 0.2689 1
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0046 0.0253
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0159 0.0184
Onchocerca volvulus 0.013 0.0475 0.0475
Trichomonas vaginalis glutaminase, putative 0.0272 0.1058 0.9135
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0018 0.0065
Echinococcus multilocularis cpg binding protein 0.0098 0.0344 0.0399
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0002
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0214 0.0817 0.4343
Schistosoma mansoni cpg binding protein 0.0093 0.0322 0.0373
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0192 0.1022
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0054 0.0179
Echinococcus multilocularis BRK domain containing protein 0.0024 0.004 0.0046
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0068 0.0219 0.0254
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0082 0.0278 0.1014
Entamoeba histolytica recQ family DNA helicase 0.0026 0.0048 0.0086
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0101 0.0353
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0152 0.1238
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0458 0.1685
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0047 0.0249
Brugia malayi hypothetical protein 0.0018 0.0014 0.0019
Brugia malayi PHD-finger family protein 0.0032 0.0074 0.0103
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0066 0.0076
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0046 0.0253
Brugia malayi N-terminal motif family protein 0.0193 0.0733 0.101
Echinococcus granulosus calpain A 0.0019 0.0022 0.0025
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0066 0.0224
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0297 0.1157 0.2599
Loa Loa (eye worm) hypothetical protein 0.0025 0.0046 0.0244
Echinococcus multilocularis DNA methyltransferase 2, putative 0.002 0.0023 0.0026
Schistosoma mansoni zinc finger protein 0.0027 0.0052 0.006
Leishmania major telomerase reverse transcriptase, putative 0.0671 0.2689 1
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0145 0.0536 0.9045
Brugia malayi ImpB/MucB/SamB family protein 0.0097 0.034 0.0469
Brugia malayi bZIP transcription factor family protein 0.0166 0.0621 0.0856
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0015 0.0151
Echinococcus granulosus importin subunit beta 1 0.0029 0.006 0.0069
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0022 0.003 0.0089
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0111 0.0587
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0018 0.0018 0.0094
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0166 0.0621 0.0721
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0077 0.0255 0.0931
Entamoeba histolytica protein kinase, putative 0.0021 0.0028 0.0041
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0027 0.003
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0111 0.0128
Loa Loa (eye worm) hypothetical protein 0.0125 0.0453 0.2407
Brugia malayi nuclear hormone receptor 0.003 0.0066 0.0091
Loa Loa (eye worm) MBCTL1 0.0113 0.0406 0.2155
Entamoeba histolytica hypothetical protein 0.0075 0.0248 0.0539
Loa Loa (eye worm) transcription factor SMAD2 0.0376 0.1481 0.7867
Schistosoma mansoni hypothetical protein 0.003 0.0063 0.0073
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0065 0.021 0.0243
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0038 0.0097 0.0112
Onchocerca volvulus 0.0025 0.0046 0.0045
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0361 0.3059
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0101 0.0117
Schistosoma mansoni glutaminase 0.0272 0.1058 0.1229
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0047 0.0054
Loa Loa (eye worm) hypothetical protein 0.0161 0.0602 0.32
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0019 0.0076
Loa Loa (eye worm) hypothetical protein 0.0065 0.021 0.1115
Echinococcus granulosus GPCR family 2 0.0065 0.021 0.0243
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0027 0.0051 0.0059
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0091 0.0106
Brugia malayi Nuclear hormone receptor E75 0.0014 0 0.0001
Trichomonas vaginalis AGC family protein kinase 0.0043 0.0118 0.0942
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0077 0.0255 0.0352
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0458 0.1685
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0019 0.0076
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.021 0.1115
Trypanosoma brucei antigen, putative 0.0019 0.0022 0.006
Trypanosoma brucei chrX additional, unordered contigs 0.003 0.0066 0.0224
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.1094 0.4422 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0066 0.0091
Entamoeba histolytica hypothetical protein 0.0311 0.1217 0.2735
Brugia malayi MH2 domain containing protein 0.0026 0.0047 0.0065
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0075 0.0248 0.0288
Giardia lamblia Kinase, PLK 0.0102 0.0361 0.0795
Brugia malayi TAR-binding protein 0.0133 0.0486 0.067
Echinococcus granulosus neuropeptide receptor A26 0.0494 0.1967 0.2285
Loa Loa (eye worm) hypothetical protein 0.0065 0.021 0.1115
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0101 0.0139
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0018 0.002
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0037 0.0237
Toxoplasma gondii RNA-directed DNA polymerase 0.0671 0.2689 1
Echinococcus granulosus tar DNA binding protein 0.0133 0.0486 0.0564
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0097 0.034 0.0395
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0054
Loa Loa (eye worm) hypothetical protein 0.0474 0.1882 1
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0099 0.0349 0.0349
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0101 0.1618
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0007 0.0035
Brugia malayi jmjC domain containing protein 0.0041 0.0111 0.0152
Mycobacterium ulcerans hypothetical protein 0.0159 0.0591 0.5507
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Echinococcus multilocularis muscleblind protein 0.046 0.1827 0.2122
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.002 0.0023 0.006
Schistosoma mansoni serine/threonine kinase 0.0018 0.0018 0.002
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0207 0.0789 0.1087
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0047 0.0054
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0069 0.0224 0.0259
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0018 0.0018 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0018 0.002
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0028 0.0148
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.1157 1
Toxoplasma gondii exonuclease III APE 0.0039 0.0101 0.0353
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.005 0.0147 0.017
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0028 0.0055 0.0182
Brugia malayi calpain 7 0.0019 0.0022 0.003
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0066 0.0076
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0046 0.0063
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0015 0.0003 0.0003
Schistosoma mansoni calpain (C02 family) 0.0019 0.0022 0.0025
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0486 0.0564
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0097 0.034 0.0395
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0057 0.0408
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0102 0.0361 0.0419
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.1157 1
Trichomonas vaginalis flap endonuclease-1, putative 0.0082 0.0278 0.2332
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0159 0.1294
Echinococcus granulosus lamin 0.0055 0.0169 0.0195
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0079 0.0687
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0002
Brugia malayi MAP kinase sur-1 0.0053 0.0159 0.0219
Brugia malayi Importin beta-1 subunit 0.0029 0.006 0.0082
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0096 0.0332
Schistosoma mansoni exonuclease 0.0017 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0002
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0101 0.0793
Loa Loa (eye worm) mbt repeat family protein 0.0099 0.0349 0.1856
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0018 0.002
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.002 0.5
Loa Loa (eye worm) bromodomain containing protein 0.0022 0.003 0.0162
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0128 0.0467 0.0542
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.004
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0019 0.0022 0.006
Echinococcus multilocularis dna polymerase eta 0.0125 0.0453 0.0526
Schistosoma mansoni calpain-7 (C02 family) 0.0019 0.0022 0.0025
Brugia malayi XPG I-region family protein 0.0017 0.001 0.0014
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0051 0.015 0.0798
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Entamoeba histolytica protein kinase, putative 0.0018 0.0018 0.0017
Brugia malayi hypothetical protein 0.0014 0 0.0001
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0101 0.0785
Echinococcus multilocularis SAM and MBT domain containing protein 0.0099 0.0349 0.0405
Echinococcus multilocularis serine:threonine protein kinase N2 0.0018 0.0018 0.002
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Brugia malayi Muscleblind-like protein 0.046 0.1827 0.2519
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0133 0.0486 0.2581
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0018 0.0018 0.0094
Echinococcus multilocularis muscleblind protein 1 0.046 0.1827 0.2122
Schistosoma mansoni DNA helicase recq5 0.0051 0.015 0.0174
Plasmodium vivax DNA repair protein RAD2, putative 0.0017 0.001 0.0014
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0 0.0001
Toxoplasma gondii hypothetical protein 0.0049 0.0141 0.0501
Echinococcus granulosus protein kinase c iota type 0.0018 0.0018 0.002
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.0048 0.0158
Loa Loa (eye worm) AGC/NDR protein kinase 0.0018 0.0018 0.0094
Plasmodium falciparum flap endonuclease 1 0.0082 0.0278 0.1011
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0066 0.0091
Loa Loa (eye worm) AGC/AKT protein kinase 0.0018 0.0018 0.0094
Brugia malayi mbt repeat family protein 0.0099 0.0349 0.0482
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0062 0.0071
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0017 0.001 0.0014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0015 0.0041
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0089 0.0103
Schistosoma mansoni calpain-7 (C02 family) 0.0019 0.0022 0.0025
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0 0.0001
Brugia malayi Calcitonin receptor-like protein seb-1 0.0207 0.0789 0.1087
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0047 0.0054
Loa Loa (eye worm) hypothetical protein 0.0045 0.0126 0.0672
Brugia malayi Protein kinase domain containing protein 0.0043 0.0118 0.0163
Schistosoma mansoni sex comb on midleg homolog 0.0099 0.0349 0.0405
Brugia malayi Latrophilin receptor protein 2 0.0065 0.021 0.0289
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0153 0.055
Leishmania major modification methylase-like protein 0.002 0.0023 0.0063
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0516 0.0599
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.006 0.0186 0.0672
Echinococcus multilocularis zinc finger protein 0.0027 0.0052 0.006
Echinococcus multilocularis snurportin 1 0.0307 0.1199 0.1392
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0458 0.1685
Trypanosoma brucei unspecified product 0.0067 0.0217 0.0786
Echinococcus granulosus calpain 7 C02 family 0.0019 0.0022 0.0025
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0063 0.0211
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0246 0.0895
Schistosoma mansoni SET domain protein 0.0038 0.0097 0.0112
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0099 0.0349 0.0405
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0051 0.0059
Brugia malayi Telomerase reverse transcriptase 0.1785 0.7253 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0046 0.0244
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0159 0.057
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0046 0.0253
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0066 0.0224
Loa Loa (eye worm) hypothetical protein 0.0059 0.0183 0.0974
Loa Loa (eye worm) XPG I-region family protein 0.0017 0.001 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0057 0.0408
Echinococcus granulosus histone lysine methyltransferase setb 0.005 0.0147 0.017
Loa Loa (eye worm) hypothetical protein 0.0141 0.0521 0.2767
Loa Loa (eye worm) hypothetical protein 0.0065 0.021 0.1115
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0066 0.0224
Echinococcus multilocularis flap endonuclease 1 0.0082 0.0278 0.0322
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0066 0.0224
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0045 0.0299
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0051 0.015 0.0207
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0022 0.006
Brugia malayi hypothetical protein 0.0016 0.0007 0.001
Leishmania major hypothetical protein, conserved 0.0017 0.001 0.0017
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.002 0.0023 0.006
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0336
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0051 0.015 0.0536
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0017 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0026 0.0048 0.0256
Schistosoma mansoni smad1 5 8 and 0.0026 0.0047 0.0054
Echinococcus multilocularis dna polymerase kappa 0.0126 0.0458 0.0532
Echinococcus multilocularis jun protein 0.0166 0.0621 0.0721
Echinococcus multilocularis calpain 5 0.0019 0.0022 0.0025
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0046 0.015
Plasmodium vivax hypothetical protein, conserved 0.003 0.0063 0.0211
Loa Loa (eye worm) hypothetical protein 0.0046 0.013 0.0692
Echinococcus multilocularis serine:threonine protein kinase N2 0.0018 0.0018 0.002
Onchocerca volvulus 0.0099 0.0349 0.0349
Brugia malayi Nuclear hormone receptor E75 0.0014 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.005 0.0147 0.0782
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0159 0.0184
Loa Loa (eye worm) hypothetical protein 0.0474 0.1882 1
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0 0.0001
Giardia lamblia PHD finger protein 15 0.003 0.0063 0.012
Giardia lamblia Fructose-bisphosphate aldolase 0.0297 0.1157 0.2599
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0159 0.057
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.0147 0.017
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0152 0.1238
Schistosoma mansoni blooms syndrome DNA helicase 0.0067 0.0217 0.0251
Trypanosoma brucei DNA polymerase eta, putative 0.0125 0.0453 0.1667
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Trichomonas vaginalis STE family protein kinase 0.0077 0.0255 0.2138
Onchocerca volvulus 0.0055 0.0169 0.0168
Loa Loa (eye worm) calpain 5 0.0019 0.0022 0.0115
Brugia malayi chromobox protein homolog 3 0.004 0.0104 0.0144
Schistosoma mansoni zinc finger protein 0.0016 0.0006 0.0006
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0043 0.0118 0.0628
Loa Loa (eye worm) inositol-1 0.0037 0.0096 0.0508
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0111 0.0128
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0051 0.015 0.0536
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0066 0.0076
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0045 0.0299
Trypanosoma cruzi polo-like protein kinase, putative 0.0102 0.0361 0.1325
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0671 0.2689 1
Echinococcus granulosus intermediate filament protein 0.0055 0.0169 0.0195
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0046 0.0253
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0022 0.006
Brugia malayi RNA recognition motif domain containing protein 0.0133 0.0486 0.067
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0045 0.0299
Schistosoma mansoni hypothetical protein 0.0169 0.0634 0.0736
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0013 0.0014
Schistosoma mansoni phd finger protein 0.0016 0.0009 0.001
Schistosoma mansoni bromodomain containing protein 0.0071 0.0234 0.0271
Brugia malayi nuclear receptor NHR-88 0.0014 0 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0045 0.0299
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0027 0.003
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0486 0.0564
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0054 0.0285
Loa Loa (eye worm) hypothetical protein 0.0025 0.0046 0.0244
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0012 0.0013
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0007 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0361 0.3059
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0037 0.0095 0.0329
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0019 0.0022 0.006
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.0011 0.0013
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0022 0.006
Plasmodium vivax exonuclease I, putative 0.0017 0.001 0.0014
Brugia malayi CXXC zinc finger family protein 0.0093 0.0322 0.0444
Echinococcus granulosus muscleblind protein 0.046 0.1827 0.2122
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0017 0.001 0.0014
Echinococcus granulosus calpain 5 0.0019 0.0022 0.0025
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0096 0.0193
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0058 0.0181 0.0651
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.004
Loa Loa (eye worm) hypothetical protein 0.003 0.0066 0.035
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0026 0.0049 0.0341
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0022 0.006
Schistosoma mansoni smad1 5 8 and 0.0026 0.0047 0.0054
Brugia malayi hypothetical protein 0.013 0.0475 0.0655
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0076 0.0088
Echinococcus granulosus dna polymerase kappa 0.0126 0.0458 0.0532
Giardia lamblia DNA damage repair protein 0.003 0.0066 0.0126
Echinococcus granulosus neuropeptide s receptor 0.0494 0.1967 0.2285
Loa Loa (eye worm) hypothetical protein 0.0027 0.0051 0.0273
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Trypanosoma cruzi DNA polymerase eta, putative 0.0058 0.0178 0.0644
Brugia malayi p70 ribosomal S6 kinase beta 0.0018 0.0018 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0458 0.1685
Echinococcus multilocularis smad 0.0026 0.0047 0.0054
Echinococcus granulosus dual specificity mitogen activated protein 0.0077 0.0255 0.0296
Brugia malayi MH2 domain containing protein 0.0026 0.0047 0.0065
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0096 0.0744
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0051 0.015 0.0174
Plasmodium vivax flap endonuclease 1, putative 0.0082 0.0278 0.1011
Echinococcus granulosus serine:threonine protein kinase N2 0.0018 0.0018 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0458 0.1685
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0082 0.0278 0.1014
Echinococcus granulosus zinc finger protein 0.0027 0.0052 0.006
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0066 0.0076
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0104 0.0369 0.1356
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0018 0.0065
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0117 0.0116
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.005 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0018 0.002
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0017 0.001 0.0017
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0066 0.0076
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0002
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.0339 0.0393
Loa Loa (eye worm) AGC/PKN protein kinase 0.0018 0.0018 0.0094
Schistosoma mansoni microtubule-associated protein tau 0.2115 0.8607 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0069 0.0368
Echinococcus granulosus microtubule associated protein 2 0.2115 0.8607 1
Loa Loa (eye worm) runx1 0.0059 0.0185 0.0985
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0069 0.0224 0.0259
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0066 0.035
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0096 0.0335
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0671 0.2689 1
Echinococcus granulosus endonuclease exonuclease phosphatase 0.04 0.1579 0.1834
Loa Loa (eye worm) hypothetical protein 0.004 0.0104 0.0555
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0516 0.0599
Plasmodium falciparum phd finger protein, putative 0.003 0.0063 0.0211
Echinococcus multilocularis protein kinase c iota type 0.0018 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.004
Schistosoma mansoni calpain C (C02 family) 0.0019 0.0022 0.0025
Mycobacterium ulcerans hypothetical protein 0.003 0.0066 0.0443
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0007 0.0008
Echinococcus multilocularis dual specificity mitogen activated protein 0.0077 0.0255 0.0296
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0159 0.0184
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Entamoeba histolytica deoxycytidyl transferase, putative 0.0097 0.034 0.0748
Echinococcus granulosus Smad4 0.0026 0.0047 0.0054
Onchocerca volvulus 0.0044 0.0124 0.0123
Loa Loa (eye worm) RNA binding protein 0.0133 0.0486 0.2581
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0 0.0001
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0007 0.0007
Trypanosoma brucei DNA polymerase IV, putative 0.0126 0.0458 0.1685
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0007 0.0003
Schistosoma mansoni smad1 5 8 and 0.0026 0.0047 0.0054
Mycobacterium tuberculosis Conserved hypothetical protein 0.0097 0.034 0.5705
Brugia malayi Bloom's syndrome protein homolog 0.0093 0.0323 0.0445
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0075 0.0248 0.0288
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0066 0.0076
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0094
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0142 0.0525 0.1937
Trypanosoma brucei unspecified product 0.0119 0.0429 0.1576
Loa Loa (eye worm) glutaminase 0.0272 0.1058 0.5621
Echinococcus multilocularis global transcription activator snf2l2 0.0141 0.052 0.0604
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0047 0.0054
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0301 0.1175 0.4357
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Schistosoma mansoni hypothetical protein 0.0141 0.0521 0.0605
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0207 0.0789 0.419
Schistosoma mansoni hypothetical protein 0.0029 0.0062 0.0072
Echinococcus multilocularis calpain 0.0019 0.0022 0.0025
Trichomonas vaginalis STE family protein kinase 0.0077 0.0255 0.2138
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0361 0.3059
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0311 0.1217 0.2735
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0022 0.006
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0002
Echinococcus granulosus BRK domain containing protein 0.0024 0.004 0.0046
Schistosoma mansoni nuclear hormone receptor 0.003 0.0066 0.0076
Echinococcus multilocularis musashi 0.0055 0.0169 0.0195
Schistosoma mansoni hypothetical protein 0.0075 0.0248 0.0288
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.0339 0.0393
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0063 0.0211
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0007 0.0009
Schistosoma mansoni flap endonuclease-1 0.0074 0.0245 0.0285
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0007 0.0003
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0169 0.0895
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0068 0.0219 0.0254
Brugia malayi Pre-SET motif family protein 0.0214 0.0817 0.1127
Brugia malayi F/Y-rich N-terminus family protein 0.0032 0.0073 0.0101
Loa Loa (eye worm) hypothetical protein 0.0038 0.0099 0.0527
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0018 0.0018 0.002
Loa Loa (eye worm) TAR-binding protein 0.0133 0.0486 0.2581
Loa Loa (eye worm) hypothetical protein 0.0051 0.015 0.0796
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0022 0.006
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.002 0.0023 0.0026
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0066 0.0076
Trichomonas vaginalis lymphoid specific helicase, putative 0.0028 0.0055 0.0393
Mycobacterium ulcerans DNA polymerase IV 0.0126 0.0458 0.4221
Loa Loa (eye worm) hypothetical protein 0.046 0.1827 0.9708
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0046 0.0081
Echinococcus multilocularis calpain family protein 1, d 0.0046 0.013 0.0151
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0066 0.0076
Schistosoma mansoni importin beta-1 0.0029 0.006 0.0069
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0066 0.0076
Trichomonas vaginalis DNA helicase recq, putative 0.006 0.0186 0.1532
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0104 0.0821
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0066 0.0076
Giardia lamblia DNA repair protein RAD52 0.1094 0.4422 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0164 0.0873
Echinococcus multilocularis chromobox protein 1 0.0071 0.0232 0.0269
Loa Loa (eye worm) hypothetical protein 0.0178 0.0671 0.3565
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0051 0.015 0.0174
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0054 0.0175
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.021 0.0243
Onchocerca volvulus 0.003 0.0066 0.0065
Toxoplasma gondii hypothetical protein 0.0084 0.0287 0.1047
Schistosoma mansoni protein kinase 0.0077 0.0255 0.0296
Schistosoma mansoni kinase 0.0053 0.0158 0.0183
Echinococcus multilocularis Chromo domain 0.0036 0.0088 0.0101
Mycobacterium ulcerans glutaminase 0.0272 0.1058 1
Trypanosoma brucei kinesin, putative 0.0019 0.0022 0.006
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0007 0.0007
Onchocerca volvulus Alhambra homolog 0.003 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0002
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0051 0.015 0.0174
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0082 0.0278 0.1011
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0026 0.0049 0.0341
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0018 0.002
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.0011 0.006
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0159 0.1294
Schistosoma mansoni ap endonuclease 0.0039 0.0101 0.0117
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0026 0.0049 0.0341
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0297 0.1157 0.2599
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0054 0.0175
Echinococcus multilocularis serine:threonine protein kinase 38 0.0018 0.0018 0.002
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0046 0.0063
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0066 0.035
Echinococcus granulosus dnaJ subfamily B 0.0845 0.3403 0.3954
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0046 0.0253
Echinococcus granulosus peregrin 0.0046 0.013 0.0151
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0066 0.0091
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0066 0.0076
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0015 0.0151
Toxoplasma gondii histone lysine methyltransferase SET1 0.0121 0.0437 0.1604
Brugia malayi polk-prov protein 0.0059 0.0183 0.0253
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.021 0.0289
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0007 0.0003
Brugia malayi intermediate filament protein 0.0055 0.0169 0.0232
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0066 0.0065
Brugia malayi Bromodomain containing protein 0.0083 0.0283 0.039
Trypanosoma cruzi polo-like protein kinase, putative 0.0102 0.0361 0.1325
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Echinococcus granulosus bloom syndrome protein 0.0093 0.0323 0.0375
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0059 0.0185 0.0666
Echinococcus multilocularis histone acetyltransferase MYST2 0.0113 0.0406 0.0471
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0361 0.3059
Entamoeba histolytica protein kinase, putative 0.0018 0.0018 0.0017
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0066 0.0065
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0486 0.0564
Echinococcus multilocularis calpain A 0.0069 0.0224 0.0259
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.002 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0183 0.0662
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0054 0.0179
Trypanosoma cruzi DNA polymerase kappa, putative 0.0126 0.0458 0.1685
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0159 0.0184
Loa Loa (eye worm) glutaminase 2 0.0272 0.1058 0.5621
Trypanosoma cruzi kinesin, putative 0.0019 0.0022 0.006
Brugia malayi MH1 domain containing protein 0.0026 0.0047 0.0065
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0458 0.1685
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.002 0.0023 0.0028
Schistosoma mansoni hypothetical protein 0.0845 0.3403 0.3954
Loa Loa (eye worm) CXXC zinc finger family protein 0.0093 0.0322 0.171
Entamoeba histolytica recQ family helicase, putative 0.0025 0.0044 0.0077
Loa Loa (eye worm) MH2 domain-containing protein 0.0376 0.1481 0.7867
Leishmania major DNA damage repair protein, putative 0.003 0.0066 0.0224
Entamoeba histolytica hypothetical protein 0.0075 0.0248 0.0539
Schistosoma mansoni intermediate filament proteins 0.0055 0.0169 0.0195
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0013 0.0014
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0084 0.0287 0.1047
Schistosoma mansoni coup transcription factor 0.003 0.0066 0.0076
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0022 0.006
Echinococcus multilocularis BRK domain containing protein 0.0024 0.004 0.0046
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0096 0.0335
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0018 0.0065
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Echinococcus granulosus flap endonuclease GEN 1 0.0017 0.001 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Schistosoma mansoni inositol monophosphatase 0.0037 0.0096 0.0111
Brugia malayi RNA binding protein 0.0133 0.0486 0.067
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0232 0.1231
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0077 0.0255 0.0931
Toxoplasma gondii ImpB/MucB/SamB family protein 0.003 0.0066 0.022
Trypanosoma cruzi DNA polymerase eta, putative 0.0125 0.0453 0.1667
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0096 0.0732
Brugia malayi nuclear receptor RXR 0.0014 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0104
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0084 0.0287 0.1046
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0013 0.0014
Trypanosoma brucei polo-like protein kinase 0.0102 0.0361 0.1325
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.014 0.0516 0.2744
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0159 0.1294
Loa Loa (eye worm) calpain 0.0019 0.0022 0.0115
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0516 0.0599
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0018 0.0065
Loa Loa (eye worm) hypothetical protein 0.0072 0.0236 0.1254
Brugia malayi hypothetical protein 0.0016 0.0007 0.001
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0159 0.0184
Brugia malayi jmjC domain containing protein 0.0097 0.0339 0.0467
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0041 0.0112 0.0884
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0066 0.0224
Echinococcus granulosus calpain A 0.0069 0.0224 0.0259
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0102 0.0361 0.1325
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0257 0.0299
Mycobacterium ulcerans hypothetical protein 0.0025 0.0046 0.0253
Loa Loa (eye worm) hypothetical protein 0.0113 0.0406 0.2155
Trypanosoma brucei DNA repair protein RAD2, putative 0.0017 0.001 0.0017
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0022 0.006
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0066 0.0091
Echinococcus multilocularis neuropeptide s receptor 0.0494 0.1967 0.2285
Trypanosoma brucei exonuclease, putative 0.0017 0.001 0.0017
Plasmodium falciparum DNA repair protein RAD2, putative 0.0017 0.001 0.0014
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0101 0.0478
Echinococcus granulosus chromobox protein 1 0.0071 0.0232 0.0269
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0096 0.0111
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0516 0.0599
Echinococcus granulosus smad 0.0026 0.0047 0.0054
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0069 0.0224 0.0259
Echinococcus granulosus Chromo domain 0.0036 0.0088 0.0101
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0101 0.0356
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0018 0.0065
Loa Loa (eye worm) hypothetical protein 0.0026 0.0047 0.0251
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0066 0.035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0066 0.035
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0007 0.0007
Echinococcus multilocularis lamin 0.0055 0.0169 0.0195
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0046 0.0253
Schistosoma mansoni myelin transcription factor 1 myt1 0.0113 0.0406 0.0471
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0145 0.0536 0.4969
Entamoeba histolytica hypothetical protein 0.0075 0.0248 0.0539
Entamoeba histolytica recQ family helicase, putative 0.006 0.0186 0.0398
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0066 0.0091
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0096 0.0111
Brugia malayi Pre-SET motif family protein 0.0033 0.0076 0.0105
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0301 0.1175 0.4357
Echinococcus multilocularis BRK domain containing protein 0.0024 0.004 0.0046
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0361 0.3059
Brugia malayi Inositol-1 0.0037 0.0096 0.0132
Leishmania major importin beta-1 subunit, putative 0.0023 0.0037 0.0119
Brugia malayi ImpB/MucB/SamB family protein 0.0125 0.0453 0.0625
Schistosoma mansoni tar DNA-binding protein 0.0133 0.0486 0.0564
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.005 0.0057
Plasmodium vivax calpain, putative 0.0019 0.0022 0.0057
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0111 0.0128
Echinococcus granulosus calpain 0.0019 0.0022 0.0025
Echinococcus multilocularis microtubule associated protein 2 0.2115 0.8607 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0046 0.0673
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0117 0.0928
Entamoeba histolytica calpain large subunit domain III containing protein 0.0019 0.0022 0.0026
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0022 0.006
Echinococcus multilocularis BRK domain containing protein 0.0024 0.004 0.0046
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.0525 0.1937
Onchocerca volvulus 0.0474 0.1882 0.1882
Leishmania major mitochondrial DNA polymerase beta 0.0301 0.1175 0.4357
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0 0.0002
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0066 0.0076
Trypanosoma brucei unspecified product 0.0067 0.0217 0.0786
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0516 0.0599
Giardia lamblia Sgs1 DNA helicase, putative 0.0051 0.015 0.0317
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0007 0.004
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0022 0.006
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0022 0.006
Brugia malayi nuclear hormone receptor 0.0014 0 0.0001
Brugia malayi MH1 domain containing protein 0.0026 0.0047 0.0065
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0022 0.006
Entamoeba histolytica protein kinase, putative 0.0018 0.0018 0.0017
Brugia malayi tailless protein 0.0014 0 0.0001
Echinococcus multilocularis lamin dm0 0.0055 0.0169 0.0195
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0101 0.0356
Echinococcus multilocularis importin subunit beta 1 0.0029 0.006 0.0069
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0037 0.0237
Schistosoma mansoni Smad4 0.0026 0.0047 0.0054
Trichomonas vaginalis DNA helicase recq1, putative 0.0093 0.0323 0.2727
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.006 0.0202
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0102 0.0361 0.1919
Trypanosoma cruzi DNA polymerase kappa, putative 0.0126 0.0458 0.1685
Brugia malayi Heterochromatin protein 1 0.0071 0.0232 0.0319
Brugia malayi PHD-finger family protein 0.003 0.0063 0.0087
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.006 0.0198
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.006 0.0186 0.0672
Echinococcus multilocularis BRK domain containing protein 0.0024 0.004 0.0046
Loa Loa (eye worm) hypothetical protein 0.003 0.0066 0.035
Trichomonas vaginalis STE family protein kinase 0.0077 0.0255 0.2138
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0017 0.001 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0066 0.0091
Onchocerca volvulus 0.0038 0.0099 0.0099
Leishmania major DNA polymerase kappa, putative 0.0104 0.0369 0.1356
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Onchocerca volvulus 0.0093 0.0322 0.0321
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0046 0.0081
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0063 0.0073
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0104
Loa Loa (eye worm) hypothetical protein 0.0055 0.0169 0.0895
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0018 0.0018 0.002
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0026 0.0049 0.0341
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0048 0.0155
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0066 0.0076
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.021 0.0243
Schistosoma mansoni hypothetical protein 0.0612 0.245 0.2846
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0066 0.0091
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0066 0.0076
Trypanosoma brucei DNA polymerase IV, putative 0.0119 0.0429 0.1576
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.0011 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0066 0.035
Brugia malayi SET domain containing protein 0.0015 0.0004 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0361 0.3059
Brugia malayi mbt repeat family protein 0.0099 0.0349 0.0482
Echinococcus granulosus DNA methyltransferase 2, putative 0.002 0.0023 0.0026
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0054 0.0179
Loa Loa (eye worm) hypothetical protein 0.003 0.0066 0.035
Leishmania major hypothetical protein, conserved 0.0027 0.0054 0.0179
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0046 0.0253
Schistosoma mansoni ap endonuclease 0.0039 0.0101 0.0117
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0066 0.0076
Brugia malayi BRM protein 0.0141 0.052 0.0717
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0159 0.057
Brugia malayi nuclear receptor NHR-67 0.0014 0 0.0001
Echinococcus multilocularis BRK domain 0.0024 0.004 0.0046
Brugia malayi Associated with TFs and helicases family protein 0.0036 0.0088 0.0121
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0096 0.0335
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0115 0.0409
Echinococcus granulosus protein kinase c epsilon type 0.0018 0.0018 0.002
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0101 0.0353
Schistosoma mansoni hypothetical protein 0.0065 0.021 0.0243
Schistosoma mansoni lamin 0.0055 0.0169 0.0195
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0159 0.057
Loa Loa (eye worm) hypothetical protein 0.003 0.0066 0.035
Loa Loa (eye worm) hypothetical protein 0.003 0.0066 0.035
Schistosoma mansoni hypothetical protein 0.0065 0.021 0.0243
Brugia malayi Bromodomain containing protein 0.0036 0.0088 0.0121
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0096 0.0335
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0018 0.002
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0037 0.0237
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0183 0.0662
Loa Loa (eye worm) hypothetical protein 0.003 0.0066 0.035
Brugia malayi Flap endonuclease-1 0.0082 0.0278 0.0383
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0169 0.0895
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0063 0.0073
Echinococcus granulosus chromobox protein 1 0.0071 0.0232 0.0269
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0054
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0066 0.035
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.0147 0.017
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Giardia lamblia Kinase, STE STE20 0.0077 0.0255 0.0556
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0045 0.0299
Schistosoma mansoni transcription factor LCR-F1 0.0075 0.0248 0.0288
Schistosoma mansoni hypothetical protein 0.0065 0.021 0.0243
Echinococcus multilocularis peregrin 0.0046 0.013 0.0151
Loa Loa (eye worm) hypothetical protein 0.0099 0.0349 0.1856
Schistosoma mansoni hypothetical protein 0.0021 0.0028 0.0032
Loa Loa (eye worm) hypothetical protein 0.0026 0.0047 0.0251
Schistosoma mansoni smad 0.0026 0.0047 0.0054
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0039 0.0104 0.012
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0159 0.0567
Loa Loa (eye worm) flap endonuclease-1 0.0082 0.0278 0.1475
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0007 0.001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0516 0.0599
Brugia malayi protein kinase C II. 0.0018 0.0018 0.0024
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0013 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0018 0.002
Brugia malayi hypothetical protein 0.0027 0.0054 0.0074
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0007 0.001
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Echinococcus granulosus NDR protein kinase 0.0018 0.0018 0.002
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.002 0.0023 0.006
Schistosoma mansoni DNA polymerase IV / kappa 0.003 0.0066 0.0076
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Toxoplasma gondii DNA methyltransferase 2, putative 0.002 0.0023 0.006
Brugia malayi CHD4 protein 0.0017 0.0011 0.0016
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0077 0.0255 0.0931
Brugia malayi hypothetical protein 0.0014 0 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0246 0.0895
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0037 0.0119
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0051 0.0059
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0301 0.1175 0.4357
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.005 0.0148 0.0787
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0069 0.0224 0.0259
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0038 0.0097 0.0112
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0066 0.0091
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0018 0.0018 0.0094
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0066 0.0076
Echinococcus granulosus lamin dm0 0.0055 0.0169 0.0195
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0117 0.0928
Trichomonas vaginalis AGC family protein kinase 0.0018 0.0018 0.0065
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0115 0.0409
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.002 0.0224
Schistosoma mansoni DNA polymerase eta 0.0125 0.0453 0.0526
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0054 0.0175
Schistosoma mansoni lozenge 0.0059 0.0185 0.0215
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0018 0.0018 0.002
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0058 0.0178 0.0641
Schistosoma mansoni thyroid hormone receptor 0.003 0.0066 0.0076
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0076 0.0088
Plasmodium falciparum DNA repair protein REV1, putative 0.003 0.0066 0.022
Loa Loa (eye worm) hypothetical protein 0.003 0.0066 0.035
Plasmodium falciparum importin beta, putative 0.0029 0.006 0.0198
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0104 0.0821
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.04 0.1579 0.1834
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0 0.0002
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0027 0.0142
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0046 0.0673
Plasmodium falciparum exonuclease I, putative 0.0017 0.001 0.0014
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0051 0.015 0.0536
Loa Loa (eye worm) Smad1 0.0026 0.0047 0.0249
Trypanosoma cruzi DNA polymerase kappa, putative 0.0126 0.0458 0.1685
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0066 0.0091
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0159 0.0843
Onchocerca volvulus 0.0046 0.013 0.013
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0017 0.001 0.0014
Plasmodium vivax DNA repair protein REV1, putative 0.003 0.0066 0.022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0066 0.035
Trypanosoma brucei protein kinase, putative 0.0053 0.0159 0.057
Leishmania major DNA polymerase eta, putative 0.0058 0.0178 0.0644
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0159 0.057
Trypanosoma brucei rac serine-threonine kinase, putative 0.0018 0.0018 0.0045
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0026 0.0049 0.0341
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0022 0.006
Echinococcus granulosus FTZ F1 alpha 0.003 0.0066 0.0076
Trichomonas vaginalis set domain proteins, putative 0.0243 0.0937 0.8081
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0104 0.0104
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0018 0.0018 0.002
Mycobacterium tuberculosis Conserved hypothetical protein 0.0159 0.0591 1
Trypanosoma brucei telomerase reverse transcriptase 0.0671 0.2689 1
Echinococcus granulosus flap endonuclease 1 0.0082 0.0278 0.0322
Entamoeba histolytica hypothetical protein 0.0075 0.0248 0.0539
Echinococcus multilocularis tar DNA binding protein 0.0133 0.0486 0.0564
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0307 0.1199 0.6369
Plasmodium vivax importin-beta 2, putative 0.0029 0.006 0.0198
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0046 0.015
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0066 0.0076
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0104
Schistosoma mansoni hypothetical protein 0.0135 0.0494 0.0573
Schistosoma mansoni lamin 0.0055 0.0169 0.0195
Trypanosoma cruzi kinesin, putative 0.0019 0.0022 0.006
Echinococcus granulosus DNA repair protein complementing XP G cells 0.0017 0.001 0.0011
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.002 0.0023 0.0063
Brugia malayi hypothetical protein 0.0474 0.1882 0.2595
Echinococcus multilocularis GPCR, family 2 0.0065 0.021 0.0243
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0097 0.034 0.0395
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Echinococcus granulosus disco interacting protein 2 0.0039 0.0104 0.012
Loa Loa (eye worm) calpain family protein 1 0.0065 0.021 0.1115
Echinococcus multilocularis disco interacting protein 2 0.0039 0.0104 0.012
Schistosoma mansoni SET domain protein 0.0019 0.0021 0.0023
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0025 0.0044 0.014
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0049 0.0341
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0458 0.1685
Trichomonas vaginalis DNA helicase recq, putative 0.0093 0.0323 0.2727
Trypanosoma brucei DNA polymerase IV, putative 0.0126 0.0458 0.1685
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0101 0.0206
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0369 0.1356
Leishmania major DNA polymerase eta, putative 0.0125 0.0453 0.1667
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.021 0.0243
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0113 0.0406 0.0559
Brugia malayi Hr1 repeat family protein 0.0018 0.0018 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0066 0.0091
Loa Loa (eye worm) hypothetical protein 0.0016 0.0007 0.004
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0045 0.0299
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0096 0.0744
Loa Loa (eye worm) hypothetical protein 0.0046 0.013 0.0692
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0159 0.1294
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0066 0.0091
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0018 0.0018 0.002
Entamoeba histolytica serine/threonine protein kinase, putative 0.0102 0.0361 0.0795
Echinococcus multilocularis exonuclease 1 0.0017 0.001 0.0011
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0115 0.0409
Schistosoma mansoni sex comb on midleg homolog 0.0099 0.0349 0.0405
Brugia malayi hypothetical protein 0.0075 0.0248 0.0342

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 10000 nM Inhibitory concentration against MSK-1 ChEMBL. 15955699
IC50 (binding) = 10000 nM Inhibitory concentration against MSK-1 ChEMBL. 15955699
Inhibition (binding) = 1 Ratio of RSK-1 IC50 to MSK-1 IC50 ChEMBL. 15955699
Ratio (binding) = 1 Ratio of GSK-3 IC50 to MSK-1 IC50 ChEMBL. 15955699

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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