Detailed information for compound 564590

Basic information

Technical information
  • TDR Targets ID: 564590
  • Name: ethyl-[4-(ethylamino)-6-(isopropylamino)-1,3, 5-triazin-2-yl]cyanamide
  • MW: 249.315 | Formula: C11H19N7
  • H donors: 2 H acceptors: 4 LogP: 2.65 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCNc1nc(NC(C)C)nc(n1)N(C#N)CC
  • InChi: 1S/C11H19N7/c1-5-13-9-15-10(14-8(3)4)17-11(16-9)18(6-2)7-12/h8H,5-6H2,1-4H3,(H2,13,14,15,16,17)
  • InChiKey: BMYVFEXJRSMHKX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • ethyl-[4-(ethylamino)-6-(propan-2-ylamino)-1,3,5-triazin-2-yl]cyanamide
  • ethyl-[4-(ethylamino)-6-(isopropylamino)-s-triazin-2-yl]cyanamide
  • ethyl-[4-ethylamino-6-(propan-2-ylamino)-1,3,5-triazin-2-yl]cyanamide
  • ethyl-[4-ethylamino-6-(isopropylamino)-1,3,5-triazin-2-yl]cyanamide
  • ethyl-[4-ethylamino-6-(isopropylamino)-s-triazin-2-yl]cyanamide
  • BAS 00334379
  • ZINC00346066
  • Ethyl-(4-ethylamino-6-isopropylamino-[1,3,5]triazin-2-yl)-cyanamide
  • MLS000026770
  • SMR000008631
  • STOCK1S-07952

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0022 0.0093
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0505 0.2306
Echinococcus granulosus neuropeptide s receptor 0.0479 0.2688 0.2686
Trichomonas vaginalis sucrase-isomaltase, putative 0.0074 0.0276 0.0561
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0201 0.1109
Trichomonas vaginalis glutaminase, putative 0.0854 0.4922 1
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0243 0.069
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0243 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0394 0.2186 0.2184
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0394 0.2186 0.2184
Loa Loa (eye worm) hypothetical protein 0.0121 0.0559 0.1133
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0175 0.0882 0.4033
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.031 0.1683 0.3418
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.031 0.1683 0.77
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0297 0.1606 0.4774
Loa Loa (eye worm) hypothetical protein 0.0153 0.0748 0.1517
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0062 0.021 0.0427
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0053 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0049 0.0099
Echinococcus granulosus geminin 0.0205 0.1057 0.1054
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0036 0.0053 0.0238
Trypanosoma cruzi DNA polymerase eta, putative 0.0061 0.0202 0.0918
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0078 0.0451
Brugia malayi Glycosyl hydrolases family 31 protein 0.0331 0.1811 0.3677
Brugia malayi jmjC domain containing protein 0.0263 0.1405 0.2852
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0081 0.0318 0.1448
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0041 0.008 0.016
Trypanosoma brucei DNA polymerase eta, putative 0.0061 0.0202 0.0918
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0635 0.3618 0.7349
Loa Loa (eye worm) hypothetical protein 0.0152 0.0746 0.1513
Schistosoma mansoni hypothetical protein 0.0035 0.0049 0.0046
Loa Loa (eye worm) hypothetical protein 0.0052 0.015 0.0301
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0105 0.0466 0.2129
Schistosoma mansoni bromodomain containing protein 0.014 0.0673 0.067
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0319 0.1735 0.3524
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0136 0.0273
Schistosoma mansoni CREB-binding protein 2 0.0131 0.0617 0.0615
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0505 0.1436
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0041 0.008 0.0463
Schistosoma mansoni jumonji domain containing protein 0.0036 0.0053 0.0051
Onchocerca volvulus Alhambra homolog 0.0062 0.0206 0.0496
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0095 0.0093
Loa Loa (eye worm) transcription factor SMAD2 0.0247 0.1307 0.2652
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0131 0.0128
Brugia malayi Glycosyl hydrolases family 31 protein 0.0074 0.0276 0.0558
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0229 0.0462
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0046 0.0112 0.011
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.0124
Echinococcus multilocularis sodium channel protein 0.0316 0.1717 0.1715
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0041 0.008 0.036
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0052 0.015 0.0147
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0394 0.2186 0.2184
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0041 0.008 0.036
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0201 0.0198
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.004 0.0075 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0052 0.015 0.0301
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.031 0.1683 0.4793
Mycobacterium ulcerans glutaminase 0.0854 0.4922 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0715 0.3268
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.031 0.1683 0.77
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0052 0.015 0.0147
Brugia malayi Pre-SET motif family protein 0.0093 0.0394 0.0798
Schistosoma mansoni hypothetical protein 0.0307 0.1665 0.1662
Echinococcus granulosus mixed lineage leukemia protein mll 0.0033 0.0035 0.0033
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0715 0.3268
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.0161 0.0324
Trypanosoma brucei unspecified product 0.0055 0.0168 0.0764
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0019 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.0394 0.2186 0.4441
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0053 0.0156 0.0153
Echinococcus granulosus metabotropic glutamate receptor 2 0.0104 0.0457 0.0455
Brugia malayi TAR-binding protein 0.0066 0.0229 0.0462
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0229 0.0226
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0001 0.0003
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0297 0.1606 0.4774
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0019 0.0038
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0049 0.0099
Loa Loa (eye worm) hypothetical protein 0.0064 0.0218 0.0441
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0049 0.0135
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0052 0.015 0.0147
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0505 0.1024
Schistosoma mansoni ets-related 0.0227 0.1187 0.1185
Schistosoma mansoni hypothetical protein 0.0042 0.0086 0.0083
Loa Loa (eye worm) hypothetical protein 0.0175 0.0882 0.1791
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.027 0.0267
Giardia lamblia NADH oxidase lateral transfer candidate 0.0041 0.008 0.0176
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0667 0.0664
Echinococcus granulosus metabotropic glutamate receptor 5 0.0153 0.0748 0.0745
Treponema pallidum fructose-bisphosphate aldolase 0.0617 0.3511 1
Echinococcus multilocularis Chromobox protein 3 0.0035 0.0049 0.0046
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0035 0.0046 0.0043
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0041 0.008 0.0016
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0316 0.1717 0.1715
Trypanosoma brucei ubiquitin-protein ligase, putative 0.031 0.1683 0.77
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.0171 0.0169
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0163 0.0332
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0052 0.015 0.0301
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0175 0.0882 0.256
Echinococcus granulosus importin subunit beta 1 0.003 0.0016 0.0013
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0042 0.0086 0.0124
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0301 0.1632 0.4012
Brugia malayi hypothetical protein 0.0245 0.1296 0.263
Echinococcus multilocularis 6 phosphofructokinase 0.0112 0.0505 0.0503
Echinococcus granulosus phd:f box containing protein 0.0036 0.0053 0.0051
Loa Loa (eye worm) hypothetical protein 0.0028 0.0003 0.0003
Plasmodium vivax thioredoxin reductase, putative 0.0117 0.0536 0.3173
Trichomonas vaginalis CAMK family protein kinase 0.0394 0.2186 0.4441
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0036 0.0053 0.0051
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0163 0.0332
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0036 0.0053 0.0224
Schistosoma mansoni cpg binding protein 0.0131 0.0615 0.0613
Loa Loa (eye worm) hypothetical protein 0.0057 0.018 0.0364
Loa Loa (eye worm) apoptosis regulator protein 0.0085 0.0346 0.0701
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.021 0.0427
Loa Loa (eye worm) glutaminase 2 0.0854 0.4922 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0171 0.0346
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0041 0.008 0.0463
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.0667 0.0664
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0617 0.3511 0.7132
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0201 0.0198
Trichomonas vaginalis chromobox protein, putative 0.013 0.0613 0.1246
Schistosoma mansoni steroid hormone receptor ad4bp 0.0052 0.015 0.0147
Trichomonas vaginalis chromobox protein, putative 0.0216 0.1123 0.2282
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0041 0.008 0.0077
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0034 0.0043 0.004
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0394 0.2186 0.4439
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0201 0.0265
Giardia lamblia DINP protein human, muc B family 0.0042 0.0086 0.0193
Brugia malayi Steroid receptor seven-up type 2 0.0052 0.015 0.0301
Trypanosoma cruzi ISWI complex protein 0.0031 0.0022 0.0094
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0175 0.0882 0.5197
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0201 0.0198
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0052 0.015 0.0147
Schistosoma mansoni hypothetical protein 0.0033 0.0033 0.003
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0072 0.0325
Schistosoma mansoni chromobox protein 0.0035 0.0049 0.0046
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0001 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0394 0.2186 0.4441
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0131 0.0128
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0148 0.067
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0209 0.0281
Brugia malayi PHD-finger family protein 0.0063 0.0213 0.0429
Schistosoma mansoni hypothetical protein 0.0319 0.1735 0.1733
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0049 0.0135
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0095 0.0191
Loa Loa (eye worm) hypothetical protein 0.0456 0.2556 0.5191
Mycobacterium tuberculosis Probable dehydrogenase 0.0267 0.1429 0.4231
Schistosoma mansoni transcription factor LCR-F1 0.0074 0.0281 0.0279
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0168 0.0836 0.0833
Leishmania major ATP-dependent phosphofructokinase 0.0112 0.0505 0.2306
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0201 0.0265
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0209 0.0281
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.0049 0.0196
Entamoeba histolytica phosphoglycerate kinase, putative 0.0175 0.0882 0.2511
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0052 0.015 0.0301
Loa Loa (eye worm) hypothetical protein 0.0028 0.0003 0.0003
Brugia malayi F/Y-rich N-terminus family protein 0.0064 0.0219 0.0443
Toxoplasma gondii exonuclease III APE 0.0039 0.0072 0.0338
Loa Loa (eye worm) hypothetical protein 0.0086 0.0348 0.0705
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0033 0.003
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0045 0.0109 0.0491
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0032 0.0028 0.0054
Leishmania major phosphoglycerate kinase C, glycosomal 0.0175 0.0882 0.4033
Echinococcus granulosus PHD finger protein rhinoceros 0.0062 0.0206 0.0204
Plasmodium vivax importin-beta 2, putative 0.003 0.0016 0.0083
Echinococcus multilocularis Niemann Pick C1 protein 0.0101 0.0437 0.0435
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0131 0.0128
Onchocerca volvulus 0.0035 0.0049 0.0114
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0019 0.0015
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0311 0.1691 0.7735
Leishmania major trypanothione reductase 0.0117 0.0536 0.2445
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0153 0.0748 0.0745
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0033 0.0035 0.0033
Echinococcus multilocularis protein patched 0.0043 0.0095 0.0093
Schistosoma mansoni blooms syndrome DNA helicase 0.0047 0.0118 0.0115
Schistosoma mansoni importin beta-1 0.003 0.0016 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0394 0.2186 0.4441
Brugia malayi Nuclear hormone receptor-like 1 0.0052 0.015 0.0301
Loa Loa (eye worm) hypothetical protein 0.0456 0.2556 0.5191
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0055 0.0163 0.0741
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0019 0.0097
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.031 0.1683 0.342
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0041 0.008 0.036
Mycobacterium tuberculosis Conserved hypothetical protein 0.0164 0.0814 0.2352
Trypanosoma cruzi ISWI complex protein 0.0031 0.0022 0.0094
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0505 0.1024
Treponema pallidum phosphoglycerate kinase 0.0175 0.0882 0.2474
Trichomonas vaginalis Sialidase-1 precursor, putative 0.0606 0.3448 0.7004
Echinococcus granulosus lysine specific demethylase 6a 0.0036 0.0053 0.0051
Loa Loa (eye worm) hypothetical protein 0.0033 0.0033 0.0063
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0064 0.0222 0.1008
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0019 0.0038
Onchocerca volvulus Heterochromatin protein 1 homolog 0.013 0.0613 0.148
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0052 0.015 0.0147
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0201 0.0198
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0019 0.0049
Brugia malayi hypothetical protein 0.0034 0.0038 0.0075
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.0667 0.0664
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0311 0.1691 0.7735
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0348 0.0708
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0301 0.1632 0.3216
Schistosoma mansoni cpg binding protein 0.0131 0.0615 0.0613
Onchocerca volvulus 0.0086 0.0348 0.0839
Toxoplasma gondii NADPH-glutathione reductase 0.0041 0.008 0.0383
Loa Loa (eye worm) jmjC domain-containing protein 0.0146 0.0708 0.1437
Loa Loa (eye worm) hypothetical protein 0.0032 0.0028 0.0054
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0054 0.016 0.0323
Brugia malayi 6-phosphofructokinase 0.0112 0.0505 0.1024
Brugia malayi polk-prov protein 0.0038 0.0066 0.0131
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0265 0.1417 0.288
Echinococcus granulosus peregrin 0.0072 0.0269 0.0267
Schistosoma mansoni metabotropic glutamate receptor 0.006 0.0198 0.0196
Loa Loa (eye worm) MBCTL1 0.0056 0.0171 0.0346
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0243 0.1108
Trichomonas vaginalis CAMK family protein kinase 0.0394 0.2186 0.4441
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.031 0.1683 0.77
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0035 0.0049 0.0046
Echinococcus multilocularis GA binding protein alpha chain 0.0075 0.0283 0.028
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0107 0.0476 0.0832
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0049 0.0099
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0156 0.0769 0.0766
Schistosoma mansoni chromobox protein 0.0035 0.0049 0.0046
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0209 0.0949
Echinococcus multilocularis neutral alpha glucosidase AB 0.0074 0.0276 0.0273
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0168 0.0836 0.0833
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0049 0.0099
Schistosoma mansoni chromobox protein 0.0216 0.1123 0.1121
Schistosoma mansoni nuclear hormone receptor 0.0052 0.015 0.0147
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0001 0.0003
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.004 0.0079 0.0076
Entamoeba histolytica hypothetical protein 0.0035 0.0049 0.0135
Loa Loa (eye worm) PHD-finger family protein 0.0062 0.0206 0.0417
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0229 0.0226
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0072 0.0202
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0276 0.0561
Loa Loa (eye worm) hypothetical protein 0.0054 0.0158 0.0319
Loa Loa (eye worm) glutathione reductase 0.0117 0.0536 0.1086
Loa Loa (eye worm) hypothetical protein 0.0028 0.0003 0.0003
Schistosoma mansoni chromobox protein 0.0216 0.1123 0.1121
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0041 0.008 0.036
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0263 0.1405 0.1402
Plasmodium falciparum phosphoglycerate kinase 0.0175 0.0882 0.5236
Schistosoma mansoni gabp alpha 0.0075 0.0283 0.028
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0041 0.008 0.0711
Toxoplasma gondii PHD-finger domain-containing protein 0.0062 0.0206 0.1142
Brugia malayi Thioredoxin reductase 0.0117 0.0536 0.1086
Brugia malayi jmjC domain containing protein 0.0036 0.0053 0.0106
Echinococcus granulosus phosphoglycerate kinase 1 0.0175 0.0882 0.088
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0051 0.0141 0.0749
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0035 0.0049 0.0277
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0209 0.0949
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0072 0.0144
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0038 0.0064 0.0127
Leishmania major mitochondrial DNA polymerase beta 0.0311 0.1691 0.7735
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0052 0.015 0.0301
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0052 0.015 0.0301
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.031 0.1683 0.3418
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0072 0.0325
Plasmodium falciparum heterochromatin protein 1 0.0035 0.0049 0.0277
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0052 0.015 0.0147
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0276 0.1257
Schistosoma mansoni phd/f-box containing protein 0.0036 0.0053 0.0051
Echinococcus granulosus fetal alzheimer antigen falz 0.0052 0.015 0.0147
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0078 0.0219
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0049 0.0099
Trichomonas vaginalis chromobox protein, putative 0.0216 0.1123 0.2282
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0052 0.015 0.0358
Loa Loa (eye worm) hypothetical protein 0.0035 0.0049 0.0096
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0095 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0052 0.015 0.0301
Brugia malayi Ets-domain containing protein 0.0075 0.0283 0.0572
Brugia malayi ubiquitin conjugating enzyme protein 13 0.031 0.1683 0.3418
Brugia malayi jmjC domain containing protein 0.0036 0.0053 0.0106
Trichomonas vaginalis hypothetical protein 0.0035 0.0049 0.0099
Loa Loa (eye worm) acetyltransferase 0.0156 0.0769 0.1559
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0276 0.0561
Brugia malayi MAP kinase sur-1 0.0055 0.0163 0.0329
Schistosoma mansoni hypothetical protein 0.0042 0.0086 0.0083
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0099 0.0446
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0617 0.3511 0.7132
Loa Loa (eye worm) hypothetical protein 0.0085 0.0346 0.0701
Brugia malayi hypothetical protein 0.0028 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0074 0.0281 0.0798
Giardia lamblia Kinase, PLK 0.0394 0.2186 0.6206
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0148 0.067
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0003 0.0003
Brugia malayi hypothetical protein 0.0074 0.0281 0.0569
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0505 0.1026
Entamoeba histolytica hypothetical protein 0.0074 0.0281 0.0798
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0085 0.0346 0.0701
Echinococcus granulosus bloom syndrome protein 0.0067 0.0238 0.0235
Brugia malayi jmjC domain containing protein 0.0036 0.0053 0.0106
Brugia malayi chromobox protein homolog 3 0.0121 0.0559 0.1133
Echinococcus granulosus L aminoadipate semialdehyde 0.0086 0.0348 0.0346
Loa Loa (eye worm) heterochromatin protein 1 0.0216 0.1123 0.228
Toxoplasma gondii hypothetical protein 0.005 0.0137 0.0727
Echinococcus granulosus GA binding protein alpha chain 0.0075 0.0283 0.028
Giardia lamblia Kinase, CMGC MAPK 0.0055 0.0163 0.0414
Giardia lamblia PHD finger protein 15 0.0062 0.0206 0.0538
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0243 0.0492
Schistosoma mansoni zinc finger protein 0.0031 0.0022 0.0019
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0258 0.0521
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0041 0.008 0.036
Schistosoma mansoni phosphoglycerate kinase 0.0175 0.0882 0.088
Echinococcus multilocularis CREB binding protein 0.0092 0.0388 0.0386
Trichomonas vaginalis set domain proteins, putative 0.0722 0.4138 0.8406
Schistosoma mansoni hypothetical protein 0.0031 0.0022 0.0019
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.0043 0.004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0041 0.008 0.036
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.031 0.1683 1
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0265 0.1417 0.4035
Trypanosoma cruzi trypanothione reductase, putative 0.0041 0.008 0.036
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0072 0.0154
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0041 0.008 0.036
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0019 0.0038
Loa Loa (eye worm) thioredoxin reductase 0.0117 0.0536 0.1086
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0001 0.0003
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0265 0.1417 0.288
Schistosoma mansoni DNA helicase recq5 0.004 0.0075 0.0072
Echinococcus multilocularis GPCR, family 2 0.0033 0.0033 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0052 0.015 0.0301
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0041 0.008 0.036
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0033 0.0063
Mycobacterium ulcerans phosphoglycerate kinase 0.0175 0.0882 0.167
Brugia malayi PHD-finger family protein 0.0062 0.0206 0.0417
Echinococcus granulosus alkaline phosphatase 0.0168 0.0836 0.0833
Echinococcus granulosus chromobox protein 2 0.0035 0.0049 0.0046
Echinococcus multilocularis dna polymerase eta 0.0061 0.0202 0.0199
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.0049 0.0046
Loa Loa (eye worm) hypothetical protein 0.0035 0.0049 0.0096
Echinococcus granulosus zinc finger protein 0.0052 0.0149 0.0146
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0066 0.0295
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.021 0.0427
Brugia malayi hypothetical protein 0.0028 0.0003 0.0003
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.004 0.0079 0.0076
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0267 0.1429 0.4231
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0505 0.1026
Loa Loa (eye worm) hypothetical protein 0.0077 0.0299 0.0604
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0168 0.0836 0.0833
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0316 0.1717 0.7855
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0276 0.0561
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0074 0.0281 0.0279
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0051 0.0141 0.0826
Loa Loa (eye worm) hypothetical protein 0.0052 0.015 0.0301
Trypanosoma brucei polo-like protein kinase 0.0394 0.2186 1
Loa Loa (eye worm) hypothetical protein 0.0245 0.1296 0.263
Schistosoma mansoni metabotropic glutamate receptor 0.0104 0.0457 0.0455
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0055 0.0163 0.0741
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0505 0.1026
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0131
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0168 0.0836 0.0833
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0209 0.0949
Brugia malayi glutathione reductase 0.0117 0.0536 0.1086
Echinococcus multilocularis jumonji domain containing protein 0.0086 0.0351 0.0348
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0041 0.008 0.036
Schistosoma mansoni microtubule-associated protein tau 0.1403 0.8192 0.8191
Loa Loa (eye worm) hypothetical protein 0.0052 0.015 0.0301
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0052 0.015 0.0147
Schistosoma mansoni hypothetical protein 0.0033 0.0033 0.003
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0101 0.0437 0.1242
Echinococcus granulosus dna polymerase eta 0.0061 0.0202 0.0199
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0041 0.008 0.0023
Entamoeba histolytica hypothetical protein 0.0074 0.0281 0.0798
Mycobacterium tuberculosis Probable oxidoreductase 0.0297 0.1606 0.4774
Trypanosoma brucei Enriched in surface-labeled proteome protein 12 0.0105 0.0466 0.2129
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0201 0.0265
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0041 0.008 0.036
Loa Loa (eye worm) hypothetical protein 0.0061 0.0202 0.0407
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0128 0.0598 0.0596
Schistosoma mansoni phosphatidylserine receptor 0.0036 0.0053 0.0051
Brugia malayi Ets-domain containing protein 0.0075 0.0283 0.0572
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0033 0.0035 0.0033
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.031 0.1683 0.1681
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0243 0.1108
Brugia malayi Importin beta-1 subunit 0.003 0.0016 0.003
Echinococcus multilocularis snurportin 1 0.0319 0.1735 0.1733
Leishmania major DNA polymerase kappa, putative 0.0042 0.0086 0.0388
Loa Loa (eye worm) hypothetical protein 0.0036 0.0053 0.0106
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0584 0.3315 1
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0078 0.0171
Echinococcus multilocularis protein dispatched 1 0.0049 0.0132 0.0129
Schistosoma mansoni DNA helicase recq1 0.004 0.0075 0.0072
Trichomonas vaginalis CAMK family protein kinase 0.0394 0.2186 0.4441
Loa Loa (eye worm) hypothetical protein 0.0036 0.0053 0.0106
Plasmodium vivax heterochromatin protein 1, putative 0.0035 0.0049 0.0277
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0505 0.1436
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0074 0.0276 0.0783
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0038 0.0062 0.0124
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0052 0.015 0.0147
Echinococcus granulosus tar DNA binding protein 0.0066 0.0229 0.0226
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0019 0.0038
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0086 0.0172
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0131 0.0128
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0052 0.015 0.0147
Trichomonas vaginalis CAMK family protein kinase 0.0394 0.2186 0.4441
Echinococcus granulosus intestinal type alkaline phosphatase 0.0168 0.0836 0.0833
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.0703 0.07
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.015 0.0147
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0265 0.1417 0.288
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0038 0.0064 0.0061
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0001 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0209 0.0949
Loa Loa (eye worm) CBP-B 0.0093 0.0395 0.0799
Brugia malayi Bromodomain containing protein 0.0083 0.0333 0.0673
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0129 0.0604 0.0601
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0001 0.0003
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0035 0.0049 0.0046
Brugia malayi Phosphoglycerate kinase 0.0064 0.0222 0.0448
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0209 0.0949
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0052 0.015 0.0147
Schistosoma mansoni apoptosis regulator bax 0.0085 0.0346 0.0344
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0263 0.1405 0.1402
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.004 0.0075 0.0432
Plasmodium falciparum JmjC domain-containing protein, putative 0.0036 0.0053 0.0305
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0053 0.0106
Mycobacterium ulcerans hypothetical protein 0.0164 0.0814 0.153
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0022 0.0093
Loa Loa (eye worm) hypothetical protein 0.0035 0.0049 0.0096
Brugia malayi hypothetical protein 0.0038 0.0062 0.0124
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.003 0.0016 0.0029
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0072 0.007
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0202 0.1039 0.1036
Brugia malayi CHD4 protein 0.0046 0.0112 0.0225
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0035 0.0049 0.0196
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0074 0.0276 0.1559
Brugia malayi acetyltransferase, GNAT family protein 0.0156 0.0769 0.1559
Plasmodium falciparum phd finger protein, putative 0.0062 0.0206 0.1215
Brugia malayi nuclear receptor RXR 0.0028 0.0003 0.0003
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0265 0.1417 0.2878
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0617 0.3511 0.7132
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.0109 0.0221
Entamoeba histolytica hypothetical protein 0.0035 0.0049 0.0135
Trypanosoma brucei glucosidase, putative 0.0074 0.0276 0.1257
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0584 0.3315 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0049 0.0135
Echinococcus multilocularis ecdysone induced protein 78C 0.0052 0.015 0.0147
Echinococcus granulosus Chromo domain 0.0035 0.0049 0.0046
Brugia malayi TAZ zinc finger family protein 0.0131 0.0617 0.1252
Brugia malayi ImpB/MucB/SamB family protein 0.0035 0.0046 0.009
Entamoeba histolytica hypothetical protein 0.0074 0.0281 0.0798
Loa Loa (eye worm) hypothetical protein 0.003 0.0016 0.003
Loa Loa (eye worm) hypothetical protein 0.0035 0.0049 0.0096
Echinococcus granulosus FTZ F1 alpha 0.0052 0.015 0.0147
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0049 0.0099
Loa Loa (eye worm) hypothetical protein 0.0128 0.0598 0.1213
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.004 0.0075 0.0352
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0035 0.0049 0.0046
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.031 0.1683 1
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0243 0.0241
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0041 0.008 0.0077
Trypanosoma brucei phosphoglycerate kinase 0.0175 0.0882 0.4033
Schistosoma mansoni lozenge 0.0057 0.0179 0.0176
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0243 0.0241
Echinococcus multilocularis geminin 0.0205 0.1057 0.1054
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.004 0.0075 0.0149
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0041 0.0084 0.0406
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0209 0.0949
Treponema pallidum licC protein (licC) 0.0107 0.0476 0.1309
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0163 0.0332
Echinococcus multilocularis neuropeptide s receptor 0.0479 0.2688 0.2686
Echinococcus granulosus thioredoxin glutathione reductase 0.0119 0.0545 0.0542
Trypanosoma brucei phosphoglycerate kinase 0.0064 0.0222 0.1008
Onchocerca volvulus Serine\/threonine kinase homolog 0.0394 0.2186 0.5281
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0175 0.0882 0.1793
Trichomonas vaginalis bromodomain-containing protein, putative 0.0051 0.0141 0.0286
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.031 0.1683 1
Trichomonas vaginalis DNA polymerase eta, putative 0.0062 0.0209 0.0424
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0052 0.015 0.0301
Mycobacterium ulcerans hypothetical protein 0.0107 0.0476 0.0832
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0105 0.0466 0.2129
Leishmania major DNA polymerase eta, putative 0.0037 0.0059 0.0264
Echinococcus granulosus survival motor neuron protein 1 0.0245 0.1296 0.1293
Loa Loa (eye worm) jmjC domain-containing protein 0.0128 0.0598 0.1213
Brugia malayi Bromodomain containing protein 0.0072 0.0269 0.0545
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0019 0.0038
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.0171 0.0169
Echinococcus granulosus microtubule associated protein 2 0.1403 0.8192 0.8191
Echinococcus granulosus aryl hydrocarbon receptor 0.0054 0.016 0.0157
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0037 0.0059 0.0257
Onchocerca volvulus Protein cycle homolog 0.0038 0.0064 0.0151
Loa Loa (eye worm) glutamate receptor 0.0049 0.0129 0.0259
Loa Loa (eye worm) CHromoDomain protein family member 0.0046 0.0112 0.0225
Trypanosoma brucei hypothetical protein, conserved 0.0105 0.0466 0.2129
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0265 0.1417 0.4035
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0175 0.0882 0.1793
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0117 0.0536 0.1499
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0052 0.015 0.0147
Echinococcus multilocularis neuropeptide receptor A26 0.0479 0.2688 0.2686
Trypanosoma brucei hypothetical protein, conserved 0.0105 0.0466 0.2129
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0229 0.0226
Giardia lamblia Fructose-bisphosphate aldolase 0.0617 0.3511 1
Brugia malayi Pre-SET motif family protein 0.0635 0.3618 0.7349
Loa Loa (eye worm) bromodomain containing protein 0.0041 0.0085 0.017
Echinococcus multilocularis lysine specific demethylase 6a 0.0036 0.0053 0.0051
Brugia malayi jmjC domain containing protein 0.0146 0.0708 0.1437
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0265 0.1417 0.288
Schistosoma mansoni hypothetical protein 0.0033 0.0033 0.003
Schistosoma mansoni survival motor neuron protein 0.005 0.0136 0.0133
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0229 0.0462
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0156 0.0769 0.0766
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0617 0.3511 0.7132
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0041 0.008 0.0105
Echinococcus granulosus neuropeptide receptor A26 0.0479 0.2688 0.2686
Plasmodium falciparum glutathione reductase 0.0117 0.0536 0.3173
Schistosoma mansoni DNA polymerase eta 0.0061 0.0202 0.0199
Brugia malayi Cytochrome P450 family protein 0.0054 0.0161 0.0324
Echinococcus multilocularis Chromo domain 0.0035 0.0049 0.0046
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0093 0.0394 0.2266
Echinococcus multilocularis lysine specific demethylase 5A 0.0135 0.0645 0.0642
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0209 0.0949
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0049 0.0277
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0041 0.008 0.0463
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0072 0.0147
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0265 0.1417 0.2878
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0046 0.0112 0.011
Brugia malayi mbt repeat family protein 0.0049 0.0131 0.0263
Echinococcus granulosus methyl CpG binding domain protein 2 0.0034 0.0043 0.004
Toxoplasma gondii PHD-finger domain-containing protein 0.0062 0.0206 0.1142
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0128 0.0598 0.0596
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0112 0.0508 0.1029
Echinococcus multilocularis chromobox protein 1 0.0216 0.1123 0.1121
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0163 0.0741
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0062 0.021 0.0427
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0267 0.1429 0.4231
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0085 0.0346 0.0344
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0175 0.0882 0.5197
Echinococcus multilocularis chromobox protein 2 0.0035 0.0049 0.0046
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0016 0.0067
Brugia malayi jmjC domain containing protein 0.0036 0.0053 0.0106
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.0667 0.0664
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0036 0.0053 0.0238
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0032 0.0028 0.0054
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0049 0.0277
Toxoplasma gondii thioredoxin reductase 0.0117 0.0536 0.3116
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0267 0.1429 0.4231
Brugia malayi ImpB/MucB/SamB family protein 0.0061 0.0202 0.0407
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0505 0.0503
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0243 0.0492
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0147 0.0715 0.3268
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0085 0.0346 0.0344
Brugia malayi Metabotropic glutamate receptor precursor. 0.0124 0.0577 0.117
Plasmodium vivax phosphoglycerate kinase, putative 0.0175 0.0882 0.5236
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0041 0.008 0.0023
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.0059 0.0264
Trypanosoma brucei phosphoglycerate kinase 0.0175 0.0882 0.4033
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0049 0.0099
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0505 0.2306
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0049 0.0099
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0064 0.0222 0.1008
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0049 0.0099
Trypanosoma brucei protein kinase, putative 0.0055 0.0163 0.0741
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0617 0.3511 0.7132
Echinococcus granulosus mitogen activated protein kinase 3 0.0055 0.0163 0.016
Trichomonas vaginalis maltase-glucoamylase, putative 0.0074 0.0276 0.0561
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0041 0.008 0.036
Trichomonas vaginalis conserved hypothetical protein 0.0606 0.3448 0.7004
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0148 0.0866
Echinococcus granulosus chromobox protein 1 0.0216 0.1123 0.1121
Trichomonas vaginalis DNA helicase recq, putative 0.0067 0.0238 0.0484
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0055 0.0163 0.0329
Brugia malayi Calcitonin receptor-like protein seb-1 0.0103 0.0452 0.0916
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0052 0.015 0.0147
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0052 0.015 0.0147
Loa Loa (eye worm) steroid hormone receptor 0.0052 0.015 0.0301
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0105 0.0466 0.2129
Schistosoma mansoni RAR-like nuclear receptor 0.0052 0.015 0.0147
Leishmania major alpha glucosidase II subunit, putative 0.0074 0.0276 0.1257
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0311 0.1691 0.7735
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0348 0.0708
Echinococcus multilocularis microtubule associated protein 2 0.1403 0.8192 0.8191
Brugia malayi phosphofructokinase 0.0112 0.0505 0.1024
Echinococcus multilocularis lysosomal alpha glucosidase 0.0331 0.1811 0.1808
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.021 0.0427
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0085 0.0346 0.0344
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0128 0.0598 0.0596
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0133 0.063 0.0627
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0028 0.0003 0.0003
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0019 0.0015
Schistosoma mansoni thyroid hormone receptor 0.0052 0.015 0.0147
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0072 0.0325
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0099 0.0446
Echinococcus granulosus CREB binding protein 0.0131 0.0617 0.0615
Schistosoma mansoni hypothetical protein 0.0074 0.0281 0.0279
Entamoeba histolytica serine/threonine protein kinase, putative 0.0394 0.2186 0.6225
Echinococcus granulosus CREB binding protein 0.0084 0.0338 0.0335
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0229 0.0462
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0099 0.0446
Loa Loa (eye worm) hypothetical protein 0.0049 0.0131 0.0263
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0033 0.0063
Echinococcus multilocularis jumonji domain containing 1A 0.0036 0.0053 0.0051
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.0171 0.0169
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0276 0.0561
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0041 0.008 0.036
Schistosoma mansoni glutaminase 0.0854 0.4922 0.4921
Brugia malayi photoreceptor-specific nuclear receptor 0.0052 0.015 0.0301
Loa Loa (eye worm) hypothetical protein 0.0052 0.0148 0.0297
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0049 0.0099
Schistosoma mansoni hypothetical protein 0.0042 0.0086 0.0083
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0033 0.0035 0.0033
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0103 0.0452 0.0916
Loa Loa (eye worm) phosphofructokinase 0.0112 0.0505 0.1024
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0049 0.0099
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0202 0.1039 0.1036
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0148 0.0866
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0133 0.063 0.0627
Echinococcus multilocularis expressed conserved protein 0.0094 0.0401 0.0398
Schistosoma mansoni retinoic acid receptor RXR 0.0052 0.015 0.0147
Loa Loa (eye worm) hypothetical protein 0.0103 0.0452 0.0916
Echinococcus multilocularis phosphoglycerate kinase 1 0.0175 0.0882 0.088
Leishmania major phosphoglycerate kinase B, cytosolic 0.0175 0.0882 0.4033
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0139 0.0667 0.1353
Brugia malayi CHE-14 protein 0.0043 0.0095 0.0191
Schistosoma mansoni phosphoglycerate kinase 0.0175 0.0882 0.088
Loa Loa (eye worm) hypothetical protein 0.0052 0.015 0.0301
Brugia malayi Niemann-Pick C1 protein precursor 0.0101 0.0437 0.0886
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0038 0.0064 0.0127
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0112 0.0505 0.1394
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0265 0.1417 0.4006
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0052 0.015 0.0147
Brugia malayi Associated with TFs and helicases family protein 0.0035 0.0049 0.0096
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0072 0.007
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.015 0.0147
Echinococcus granulosus lysosomal alpha glucosidase 0.0331 0.1811 0.1808
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0081 0.0318 0.1448
Loa Loa (eye worm) fli-1 protein 0.0227 0.1187 0.241
Loa Loa (eye worm) ATP-dependent DNA helicase 0.004 0.0075 0.0149
Loa Loa (eye worm) MH2 domain-containing protein 0.0247 0.1307 0.2652
Brugia malayi glutaminase DH11.1 0.0854 0.4922 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.0667 0.0664
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0584 0.3315 1
Onchocerca volvulus 0.0722 0.4138 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0209 0.0949
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0052 0.015 0.0301
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0019 0.0097
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0049 0.0099
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0066 0.0295
Leishmania major DNA polymerase eta, putative 0.0061 0.0202 0.0918
Schistosoma mansoni alpha-glucosidase 0.0285 0.1536 0.1534
Loa Loa (eye worm) RecQ helicase 0.0067 0.0238 0.0481
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0048 0.0124 0.0251
Schistosoma mansoni hypothetical protein 0.0085 0.0346 0.0344
Brugia malayi PHD-finger family protein 0.0031 0.0022 0.0043
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0121 0.0559 0.1347
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0019 0.0038
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.003 0.0016 0.0029
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0265 0.1417 0.2773
Onchocerca volvulus 0.0049 0.0131 0.0313
Brugia malayi MH2 domain containing protein 0.0247 0.1307 0.2652
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0074 0.0276 0.0558
Echinococcus granulosus histone acetyltransferase KAT2B 0.0051 0.0141 0.0138
Echinococcus granulosus lysine specific demethylase 5A 0.0146 0.0708 0.0706
Echinococcus multilocularis Niemann Pick C1 protein 0.0144 0.0694 0.0692
Onchocerca volvulus Protein ultraspiracle homolog 0.0052 0.015 0.0358
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0141 0.0678 0.0676
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0033 0.003
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0156 0.0707
Onchocerca volvulus 0.012 0.0552 0.1331
Entamoeba histolytica deoxycytidyl transferase, putative 0.0035 0.0046 0.0126
Trichomonas vaginalis CAMK family protein kinase 0.0195 0.1002 0.2035
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.031 0.1683 0.3418
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0297 0.1606 0.3919
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0331 0.1811 0.3677
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.015 0.0147
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0394 0.2186 1
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0135 0.0275
Echinococcus granulosus sodium channel protein 0.0316 0.1717 0.1715
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0301 0.1632 0.4854
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0042 0.0086 0.0388
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0175 0.0882 0.1343
Brugia malayi hypothetical protein 0.0456 0.2556 0.5191
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0559 0.1135
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0036 0.0053 0.0224
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0001 0.0003
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0046 0.0112 0.011
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0072 0.0418
Trypanosoma brucei trypanothione reductase 0.0117 0.0536 0.2445
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0033 0.003
Leishmania major hypothetical protein, conserved 0.0031 0.0022 0.0094
Schistosoma mansoni jumonji/arid domain-containing protein 0.0146 0.0708 0.0706
Loa Loa (eye worm) CXXC zinc finger family protein 0.012 0.0552 0.1119
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0163 0.0741
Echinococcus granulosus jumonji domain containing protein 0.0086 0.0351 0.0348
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0163 0.016
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0041 0.008 0.0383
Echinococcus granulosus snurportin 1 0.0319 0.1735 0.1733
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0061 0.0204 0.1203
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0505 0.1436
Loa Loa (eye worm) hypothetical protein 0.0088 0.0362 0.0732
Entamoeba histolytica hypothetical protein 0.0035 0.0049 0.0135
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0209 0.0949
Brugia malayi hypothetical protein 0.0054 0.0158 0.0319
Schistosoma mansoni alpha glucosidase 0.0074 0.0276 0.0273
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0073 0.007
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0265 0.1417 0.288
Loa Loa (eye worm) histone methyltransferase 0.004 0.0079 0.0158
Loa Loa (eye worm) hypothetical protein 0.0035 0.0049 0.0096
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0072 0.0144
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0072 0.0082
Loa Loa (eye worm) hypothetical protein 0.0143 0.0687 0.1393
Loa Loa (eye worm) hypothetical protein 0.0035 0.0049 0.0096
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.0124
Loa Loa (eye worm) hypothetical protein 0.0035 0.0049 0.0096
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0617 0.3511 0.7132
Onchocerca volvulus 0.0095 0.0403 0.0971
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0062 0.0206 0.0204
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0073 0.007
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0131 0.0263
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0052 0.015 0.0301
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0016 0.0067
Echinococcus multilocularis PHD finger protein rhinoceros 0.0062 0.0206 0.0204
Onchocerca volvulus 0.0265 0.1417 0.3423
Onchocerca volvulus 0.0052 0.015 0.0358
Leishmania major hypothetical protein, conserved 0.0052 0.0148 0.067
Brugia malayi Heterochromatin protein 1 0.0216 0.1123 0.228
Onchocerca volvulus 0.005 0.0136 0.0325
Loa Loa (eye worm) hypothetical protein 0.0052 0.015 0.0301
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0617 0.3511 1
Echinococcus granulosus JmjC domain containing protein 4 0.0036 0.0053 0.0051
Loa Loa (eye worm) hypothetical protein 0.0095 0.0403 0.0816
Loa Loa (eye worm) glutamate receptor 0.0124 0.0577 0.117
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0086 0.0388
Toxoplasma gondii histone lysine methyltransferase SET1 0.0241 0.1273 0.7538
Schistosoma mansoni hypothetical protein 0.0062 0.0206 0.0204
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0074 0.0281 0.0279
Echinococcus multilocularis thyroid hormone receptor alpha 0.0052 0.015 0.0147
Echinococcus granulosus chromobox protein 1 0.0216 0.1123 0.1121
Brugia malayi hypothetical protein 0.0035 0.0049 0.0096
Echinococcus multilocularis cpg binding protein 0.0131 0.0615 0.0613
Echinococcus granulosus mitogen activated protein kinase 0.0055 0.0163 0.016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0052 0.015 0.0301
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0131 0.0617 0.0615
Echinococcus multilocularis JmjC domain containing protein 4 0.0036 0.0053 0.0051
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0131 0.0128
Schistosoma mansoni hypothetical protein 0.007 0.0258 0.0255
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0051 0.0141 0.0749
Schistosoma mansoni terminal deoxycytidyl transferase 0.0035 0.0046 0.0043
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0175 0.0882 0.2499
Schistosoma mansoni hypothetical protein 0.1707 1 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0035 0.0046 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0052 0.015 0.0301
Echinococcus granulosus Niemann Pick C1 protein 0.0144 0.0694 0.0692
Trichomonas vaginalis maltase-glucoamylase, putative 0.0027 0.0001 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0049 0.0099
Brugia malayi nuclear receptor NHR-88 0.0052 0.015 0.0301
Brugia malayi 6-phosphofructokinase 0.0112 0.0505 0.1024
Loa Loa (eye worm) hypothetical protein 0.0101 0.0437 0.0886
Echinococcus multilocularis dnaJ subfamily B 0.1707 1 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0201 0.0475
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0095 0.0194
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0075 0.0283 0.0572
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0081 0.0318 0.1448
Echinococcus multilocularis Protein lozenge 0.0057 0.0179 0.0176
Brugia malayi Fli-1 protein 0.0227 0.1187 0.241
Schistosoma mansoni protein phosphatase 2C 0.0036 0.0053 0.0051
Brugia malayi RNA, U transporter 1 0.0085 0.0344 0.0696
Loa Loa (eye worm) hypothetical protein 0.0099 0.0425 0.0862
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0052 0.015 0.0301
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0055 0.0163 0.0741
Echinococcus multilocularis L aminoadipate semialdehyde 0.0086 0.0348 0.0346
Onchocerca volvulus 0.0035 0.0049 0.0114
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0074 0.0276 0.0561
Echinococcus multilocularis lysosomal alpha glucosidase 0.0331 0.1811 0.1808
Echinococcus multilocularis aryl hydrocarbon receptor 0.0054 0.016 0.0157
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0072 0.0154
Brugia malayi mbt repeat family protein 0.0049 0.0131 0.0263
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0265 0.1417 0.4197
Echinococcus multilocularis thioredoxin glutathione reductase 0.0119 0.0545 0.0542
Trichomonas vaginalis chromobox protein, putative 0.013 0.0613 0.1246
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.031 0.1683 0.1681
Loa Loa (eye worm) glutaminase 0.0854 0.4922 1
Echinococcus multilocularis bloom syndrome protein 0.0067 0.0238 0.0235
Trichomonas vaginalis Heterochromatin protein, putative 0.0035 0.0049 0.0099
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0267 0.1429 0.3287
Leishmania major hypothetical protein, conserved 0.0036 0.0053 0.0238
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0052 0.015 0.0147
Loa Loa (eye worm) hypothetical protein 0.0053 0.0153 0.0309
Schistosoma mansoni hypothetical protein 0.0042 0.0086 0.0083
Onchocerca volvulus 0.0456 0.2556 0.6175
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0105 0.0466 0.2129
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0617 0.3511 0.7132
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.0043 0.004
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0072 0.0147
Echinococcus granulosus ATP dependent DNA helicase Q5 0.004 0.0075 0.0072
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0394 0.0391
Schistosoma mansoni jumonji/arid domain-containing protein 0.0146 0.0708 0.0706
Trypanosoma brucei phosphoglycerate kinase, putative 0.0064 0.0222 0.1008
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0099 0.0446
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.0124
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0209 0.0949
Mycobacterium tuberculosis Conserved hypothetical protein 0.0107 0.0476 0.1316
Entamoeba histolytica recQ family helicase, putative 0.0045 0.0109 0.0305
Echinococcus multilocularis survival motor neuron protein 1 0.0245 0.1296 0.1293
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0041 0.008 0.0463
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0064 0.0222 0.1008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0667 0.0664
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0258 0.1372 0.1369
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0105 0.0466 0.2129
Echinococcus multilocularis chromobox protein 1 0.0216 0.1123 0.1121
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0175 0.0882 0.4033
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0043
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.0171 0.0169
Plasmodium vivax JmjC domain containing protein 0.0036 0.0053 0.0305
Trichomonas vaginalis CAMK family protein kinase 0.0195 0.1002 0.2035
Giardia lamblia Phosphoglycerate kinase 0.0175 0.0882 0.2474
Brugia malayi metabotropic glutamate receptor type 2 0.006 0.0198 0.0401
Brugia malayi M-phase phosphoprotein, mpp8 0.0035 0.0049 0.0096
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0085 0.0346 0.0344
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0074 0.0276 0.0561
Echinococcus granulosus dna polymerase kappa 0.0062 0.0209 0.0206
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0041 0.008 0.036
Brugia malayi CXXC zinc finger family protein 0.012 0.0552 0.1119
Echinococcus multilocularis alkaline phosphatase 0.0168 0.0836 0.0833
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0243 0.1108
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0033 0.003
Loa Loa (eye worm) hypothetical protein 0.0122 0.0566 0.1147
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0041 0.008 0.036
Schistosoma mansoni hypothetical protein 0.005 0.0136 0.0133
Mycobacterium tuberculosis Conserved hypothetical protein 0.0107 0.0476 0.1316
Schistosoma mansoni cpg binding protein 0.012 0.0552 0.0549
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0095 0.0093
Onchocerca volvulus Bile acid receptor homolog 0.0052 0.015 0.0358
Brugia malayi Bromodomain containing protein 0.0164 0.0814 0.1651
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.004 0.0075 0.0149
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0276 0.0561
Trypanosoma brucei ISWI complex protein 0.0031 0.0022 0.0094
Onchocerca volvulus 0.0129 0.0604 0.1457
Loa Loa (eye worm) RNA binding protein 0.0066 0.0229 0.0462
Schistosoma mansoni hypothetical protein 0.0085 0.0346 0.0344
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0047 0.0117 0.0114
Brugia malayi Protein cec-1. 0.0035 0.0049 0.0096
Brugia malayi Receptor family ligand binding region containing protein 0.0032 0.0028 0.0054
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0053 0.0106
Loa Loa (eye worm) hypothetical protein 0.0052 0.015 0.0301
Echinococcus granulosus GPCR family 2 0.0033 0.0033 0.003
Echinococcus granulosus jumonji domain containing 1A 0.0036 0.0053 0.0051
Mycobacterium tuberculosis Probable reductase 0.0267 0.1429 0.4231
Giardia lamblia Sgs1 DNA helicase, putative 0.004 0.0075 0.0161
Schistosoma mansoni patched 1 0.0043 0.0095 0.0093
Echinococcus granulosus ATP dependent DNA helicase Q1 0.004 0.0075 0.0072
Trypanosoma brucei DNA polymerase IV, putative 0.0055 0.0168 0.0764
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0074 0.0276 0.0783
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0505 0.0503
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0019 0.0097
Trichomonas vaginalis mercuric reductase, putative 0.0041 0.008 0.0162
Trypanosoma cruzi trypanothione reductase, putative 0.0117 0.0536 0.2445
Loa Loa (eye worm) hypothetical protein 0.0052 0.015 0.0301
Brugia malayi serine/threonine-protein kinase plk-2 0.0394 0.2186 0.4439
Loa Loa (eye worm) hypothetical protein 0.0028 0.0003 0.0003
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0035 0.0046 0.009
Echinococcus granulosus histone lysine methyltransferase setb 0.0128 0.0598 0.0596
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0209 0.0949
Loa Loa (eye worm) runx1 0.0057 0.0179 0.0361
Echinococcus granulosus Chromobox protein 3 0.0035 0.0049 0.0046
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0093 0.0394 0.0391
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.027 0.0267
Schistosoma mansoni zinc finger protein 0.0052 0.0149 0.0146
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.0447 0.0444
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0052 0.015 0.0301
Schistosoma mansoni hypothetical protein 0.0205 0.1057 0.1054
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.004 0.0075 0.0072
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.0049 0.0046
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0243 0.1108
Echinococcus multilocularis mitogen activated protein kinase 0.0055 0.0163 0.016
Echinococcus granulosus expressed conserved protein 0.0094 0.0401 0.0398
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0035 0.0049 0.0096
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0052 0.015 0.0301
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0201 0.0913
Echinococcus multilocularis dna polymerase kappa 0.0062 0.0209 0.0206
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.004 0.0075 0.0352
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.0584 0.3315 0.6685
Trichomonas vaginalis DNA helicase recq1, putative 0.0067 0.0238 0.0484
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0052 0.015 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0049 0.0099
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0042 0.0088 0.0513
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0045 0.0109 0.0491
Loa Loa (eye worm) helicase 0.0035 0.0049 0.0096
Brugia malayi ecdysteroid receptor 0.0052 0.015 0.0301
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0559 0.1135
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0104 0.0457 0.0455
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0041 0.008 0.0077
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.0171 0.0169
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0209 0.0949
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0131 0.0313
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0041 0.008 0.036
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0139 0.0667 0.1353
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0131 0.0128
Brugia malayi Phosphoglycerate kinase 0.0175 0.0882 0.1791
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0045 0.0109 0.0491
Brugia malayi Valyl-tRNA synthetase 0.0035 0.0049 0.0096
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.005 0.0135 0.0275
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0087 0.0358 0.0356
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0055 0.0163 0.0883
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0036 0.0053 0.0238
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0148 0.079
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0052 0.015 0.0147
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0055 0.0163 0.0741
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0617 0.3511 1
Mycobacterium ulcerans hypothetical protein 0.0107 0.0476 0.0832
Schistosoma mansoni kinase 0.0201 0.1033 0.103
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0033 0.0063
Brugia malayi steroid hormone receptor 0.0052 0.015 0.0301
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0163 0.0332
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0052 0.015 0.0301
Loa Loa (eye worm) hypothetical protein 0.0052 0.015 0.0301
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0168 0.0836 0.0833
Loa Loa (eye worm) hypothetical protein 0.004 0.0075 0.0149
Schistosoma mansoni alkaline phosphatase 0.0168 0.0836 0.0833
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0019 0.0097
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0229 0.0226
Brugia malayi SET domain containing protein 0.0041 0.0084 0.0168
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0052 0.015 0.0301
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0019 0.0038
Schistosoma mansoni hypothetical protein 0.0085 0.0346 0.0344
Mycobacterium tuberculosis Probable enoyl-CoA hydratase EchA14 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) 0.0301 0.1628 0.4841
Echinococcus multilocularis mitogen activated protein kinase 3 0.0055 0.0163 0.016
Mycobacterium ulcerans 6-phosphofructokinase 0.0112 0.0505 0.0892
Brugia malayi RNA binding protein 0.0066 0.0229 0.0462
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0209 0.0949
Loa Loa (eye worm) hypothetical protein 0.007 0.0258 0.0521
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0035 0.0049 0.0277
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0062 0.0209 0.0424
Treponema pallidum NADH oxidase 0.0041 0.008 0.0176
Plasmodium vivax SET domain protein, putative 0.0093 0.0394 0.233
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0052 0.015 0.0301
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0107 0.0476 0.2757
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0085 0.0346 0.0344
Brugia malayi hypothetical protein 0.0052 0.0148 0.0297
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0131 0.0128
Echinococcus multilocularis phd:f box containing protein 0.0036 0.0053 0.0051
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0209 0.0949
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.021 0.0427
Echinococcus granulosus cpg binding protein 0.0131 0.0615 0.0613
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0052 0.015 0.0301
Echinococcus granulosus Niemann Pick C1 protein 0.0101 0.0437 0.0435
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0041 0.008 0.0016
Echinococcus granulosus neutral alpha glucosidase AB 0.0074 0.0276 0.0273
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0148 0.067
Schistosoma mansoni hypothetical protein 0.0033 0.0033 0.003
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0112 0.0505 0.1406
Schistosoma mansoni hypothetical protein 0.0087 0.0357 0.0354
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0148 0.0866
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0051 0.0141 0.0286
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0267 0.1429 0.4231
Plasmodium vivax hypothetical protein, conserved 0.0062 0.0206 0.1215
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0047 0.0117 0.0114
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0229 0.0226
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0035 0.0046 0.0043
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.021 0.0427
Echinococcus granulosus 6 phosphofructokinase 0.0112 0.0505 0.0503
Brugia malayi nuclear hormone receptor 0.0052 0.015 0.0301
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0052 0.015 0.0301
Loa Loa (eye worm) hypothetical protein 0.0043 0.0095 0.0191
Onchocerca volvulus 0.0192 0.0979 0.2364
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0022 0.0093
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0086 0.0348 0.0346
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0041 0.008 0.036
Trypanosoma cruzi polo-like protein kinase, putative 0.0394 0.2186 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.0206 0.0417
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.0171 0.0346
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0062 0.021 0.0427
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0103 0.0452 0.0916
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.031 0.1683 0.342
Plasmodium falciparum thioredoxin reductase 0.0117 0.0536 0.3173
Trichomonas vaginalis glutathione reductase, putative 0.0041 0.008 0.0162
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0209 0.0949
Chlamydia trachomatis phosphoglycerate kinase 0.0175 0.0882 1
Plasmodium falciparum thioredoxin reductase 0.0041 0.008 0.0463
Schistosoma mansoni hypothetical protein 0.0205 0.1057 0.1054
Echinococcus multilocularis FTZ F1 alpha 0.0052 0.015 0.0147
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0265 0.1417 0.288
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1676 0.982 0.982
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0038 0.0064 0.0127
Brugia malayi Bloom's syndrome protein homolog 0.0067 0.0238 0.0481
Brugia malayi hypothetical protein 0.0038 0.0064 0.0127
Plasmodium falciparum glutathione reductase 0.0041 0.008 0.0463
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0072 0.0325
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.0124
Echinococcus multilocularis peregrin 0.0072 0.0269 0.0267
Schistosoma mansoni hypothetical protein 0.0042 0.0086 0.0083
Onchocerca volvulus 0.0054 0.0158 0.038
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0505 0.1026
Trypanosoma cruzi polo-like protein kinase, putative 0.0394 0.2186 1
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.031 0.1683 0.1681
Loa Loa (eye worm) hypothetical protein 0.0028 0.0003 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0617 0.3511 0.7132
Echinococcus multilocularis importin subunit beta 1 0.003 0.0016 0.0013
Schistosoma mansoni ap endonuclease 0.0039 0.0072 0.007
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.015 0.0147
Schistosoma mansoni ap endonuclease 0.0039 0.0072 0.007
Plasmodium falciparum importin beta, putative 0.003 0.0016 0.0083
Schistosoma mansoni alpha-glucosidase 0.0285 0.1536 0.1534
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0276 0.1257
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.0049 0.0196
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0072 0.0418
Echinococcus multilocularis zinc finger protein 0.0052 0.0149 0.0146
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0041 0.008 0.0016
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0229 0.0226
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0086 0.0348 0.0705
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0003 0.0003
Echinococcus granulosus ecdysone induced protein 78C 0.0052 0.015 0.0147
Schistosoma mansoni jumonji domain containing protein 0.0221 0.1157 0.1155
Schistosoma mansoni alkaline phosphatase 0.0168 0.0836 0.0833
Plasmodium vivax glutathione reductase, putative 0.0117 0.0536 0.3173
Schistosoma mansoni thyroid hormone receptor 0.0052 0.015 0.0147
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0667 0.0664
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0055 0.0163 0.0741
Schistosoma mansoni coup transcription factor 0.0052 0.015 0.0147

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) > 260 uM PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493224] ChEMBL. No reference
Potency (functional) 0.3548 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.8184 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 112.2018 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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