Detailed information for compound 569716

Basic information

Technical information
  • TDR Targets ID: 569716
  • Name: S-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihyd roxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14, 15,16-decahydro-1H-cyclopenta[a]phenanthren-1 7-yl]-2-oxo-ethyl] 2,2-dimethylpropanethioate
  • MW: 462.642 | Formula: C26H38O5S
  • H donors: 2 H acceptors: 5 LogP: 3.57 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1CC[C@]2(C(=C1)CC[C@@H]1[C@@H]2[C@@H](O)C[C@]2([C@H]1CC[C@]2(O)C(=O)CSC(=O)C(C)(C)C)C)C
  • InChi: 1S/C26H38O5S/c1-23(2,3)22(30)32-14-20(29)26(31)11-9-18-17-7-6-15-12-16(27)8-10-24(15,4)21(17)19(28)13-25(18,26)5/h12,17-19,21,28,31H,6-11,13-14H2,1-5H3/t17-,18-,19-,21+,24-,25-,26-/m0/s1
  • InChiKey: BISFDZNIUZIKJD-XDANTLIUSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2,2-dimethylpropanethioic acid S-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] ester
  • 2,2-dimethylpropanethioic acid S-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-3-keto-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-keto-ethyl] ester
  • S-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanethioate
  • tixocortol pivalate
  • 55560-96-8
  • D06171
  • Tixocortol pivalate (USAN)

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Phosphoglycerate kinase 0.017 0.0261 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0207 0.0324 1
Schistosoma mansoni cpg binding protein 0.0159 0.0242 0.0854
Echinococcus multilocularis geminin 0.154 0.261 0.261
Echinococcus granulosus expressed protein 0.0034 0.0028 0.0029
Echinococcus multilocularis zinc finger protein 0.0059 0.007 0.007
Echinococcus granulosus histone lysine methyltransferase setb 0.019 0.0295 0.0312
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.0008 0.0168
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0039 0.0039
Schistosoma mansoni GTP-binding protein alpha subunit 0.0022 0.0006 0.0023
Echinococcus granulosus neuropeptide receptor 0.011 0.0157 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0064 0.0307
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0022 0.0006 0.0033
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0183 0.0283 0.1376
Schistosoma mansoni smad 0.0027 0.0015 0.0053
Echinococcus multilocularis peregrin 0.0072 0.0093 0.0093
Onchocerca volvulus 0.0034 0.0028 0.0128
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.0026 0.081
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0118
Trichomonas vaginalis glutathione reductase, putative 0.003 0.002 0.0092
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.1561 0.2645 1
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.006 0.006
Leishmania major pyruvate kinase 0.0032 0.0024 0.075
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0039 0.018
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0007 0.0007
Echinococcus multilocularis muscleblind protein 1 0.0145 0.0218 0.0218
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0028 0.0128
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0028 0.0722
Schistosoma mansoni tar DNA-binding protein 0.0266 0.0425 0.1498
Leishmania major cathepsin L-like protease 0.0034 0.0028 0.0854
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0062 0.0074 0.0385
Plasmodium vivax thioredoxin reductase, putative 0.0087 0.0118 0.3637
Schistosoma mansoni jumonji/arid domain-containing protein 0.0081 0.0107 0.0378
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.003 0.002 0.0629
Entamoeba histolytica phosphoglycerate kinase, putative 0.017 0.0261 0.7166
Echinococcus multilocularis pyruvate kinase 0.0032 0.0024 0.0024
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0034 0.0028 0.0143
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0194 0.597
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.0026 0.081
Echinococcus granulosus importin subunit beta 1 0.003 0.002 0.0021
Plasmodium falciparum histone acetyltransferase GCN5 0.012 0.0174 0.5365
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0028 0.0128
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0183 0.0283 0.8722
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0578 0.0959 0.1015
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0004 0.0013
Brugia malayi Thioredoxin reductase 0.0087 0.0118 0.0611
Echinococcus granulosus dnaJ subfamily B 0.1672 0.2837 0.3002
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0041 0.021
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0118
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0022 0.0006 0.0006
Trypanosoma cruzi cysteine peptidase, putative 0.0131 0.0194 0.597
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0024 0.075
Loa Loa (eye worm) hypothetical protein 0.0028 0.0017 0.0086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0028 0.0128
Loa Loa (eye worm) cysteine protease 0.0034 0.0028 0.0143
Echinococcus granulosus neuropeptide s receptor 0.0945 0.1589 0.1682
Schistosoma mansoni hypothetical protein 0.154 0.261 0.9201
Loa Loa (eye worm) hypothetical protein 0.0263 0.0419 0.2169
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0004 0.002
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0022 0.0006 0.0023
Brugia malayi CHD4 protein 0.0035 0.0029 0.0151
Loa Loa (eye worm) hypothetical protein 0.0094 0.0129 0.067
Echinococcus granulosus lysine specific demethylase 5A 0.0081 0.0107 0.0114
Schistosoma mansoni myst-related protein 0.0021 0.0005 0.0018
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.003 0.002 0.0072
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0042 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.0042 0.0041 0.0143
Trichomonas vaginalis Heterochromatin protein, putative 0.0023 0.0008 0.0032
Brugia malayi mbt repeat family protein 0.0047 0.0049 0.0252
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0512 0.0848 0.0897
Plasmodium falciparum glutathione reductase 0.0087 0.0118 0.3637
Entamoeba histolytica G protein alpha subunit, putative 0.0022 0.0006 0.0133
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0028 0.0128
Loa Loa (eye worm) MH1 domain-containing protein 0.0027 0.0015 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0028 0.0128
Onchocerca volvulus 0.0021 0.0005 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0028 0.0128
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.0026 0.0683
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0042
Schistosoma mansoni chromobox protein 0.0023 0.0008 0.0029
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0042
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0039 0.0039
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0004 0.0062
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.1561 0.2645 0.2798
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0023 0.0008 0.025
Schistosoma mansoni zinc finger protein 0.0031 0.0022 0.0078
Brugia malayi Phosphoglycerate kinase 0.017 0.0261 0.135
Entamoeba histolytica hypothetical protein 0.0023 0.0008 0.018
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.003 0.002 0.002
Leishmania major hypothetical protein, conserved 0.0207 0.0324 1
Leishmania major inositol polyphosphate 1-phosphatase, putative 0.0019 0.0002 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0039 0.018
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0004 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0026 0.0119
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.003 0.002 0.0422
Brugia malayi Pre-SET motif family protein 0.1065 0.1796 0.9292
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0062 0.0074 0.2014
Echinococcus granulosus cathepsin l1 0.0034 0.0028 0.0029
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0073 0.0094 0.01
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0004 0.0118
Echinococcus multilocularis dna polymerase eta 0.0021 0.0004 0.0004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.002 0.0629
Brugia malayi Cathepsin L-like cysteine proteinase 0.0023 0.0008 0.0042
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0085 0.0114 0.055
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0031 0.0021 0.0021
Brugia malayi MH2 domain containing protein 0.0397 0.065 0.3363
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0039 0.0041
Loa Loa (eye worm) thioredoxin reductase 0.0087 0.0118 0.0611
Brugia malayi hypothetical protein 0.0299 0.0482 0.2494
Echinococcus granulosus Smad4 0.0027 0.0015 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0028 0.0128
Trichomonas vaginalis bromodomain-containing protein, putative 0.0135 0.0201 0.0975
Echinococcus granulosus smad 0.0027 0.0015 0.0016
Echinococcus granulosus neuropeptide receptor A26 0.0945 0.1589 0.1682
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0263 0.0419 0.2169
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0178 0.0274 0.133
Loa Loa (eye worm) CXXC zinc finger family protein 0.0147 0.0221 0.1144
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0035 0.0029 0.0031
Brugia malayi Phosphoglycerate kinase 0.0063 0.0076 0.0393
Brugia malayi Latrophilin receptor protein 2 0.0263 0.0419 0.2169
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0062 0.0074 0.2295
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0449 0.0739 0.0739
Echinococcus granulosus microtubule associated protein 2 0.0669 0.1116 0.1181
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0024 0.0111
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0027 0.0015 0.0015
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0022 0.0006 0.0023
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0023 0.0008 0.0029
Brugia malayi glutathione reductase 0.0087 0.0118 0.0611
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0039 0.102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0028 0.0128
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0016 0.0486
Trypanosoma brucei ISWI complex protein 0.0031 0.0022 0.0679
Brugia malayi N-terminal motif family protein 0.0178 0.0274 0.1416
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0149 0.0224 0.0235
Plasmodium falciparum zinc finger protein, putative 0.0021 0.0005 0.0157
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0022 0.0006 0.0023
Brugia malayi Inositol monophosphatase family protein 0.0019 0.0002 0.0008
Schistosoma mansoni ran 0.0022 0.0007 0.0023
Echinococcus granulosus inositol monophosphatase 0.0019 0.0002 0.0002
Onchocerca volvulus 0.0023 0.0008 0.0032
Mycobacterium leprae conserved hypothetical protein 0.0149 0.0224 0.0841
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0034 0.0028 0.0143
Loa Loa (eye worm) mucolipin 1 0.02 0.0311 0.161
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0156 0.0235 0.0235
Leishmania major hypothetical protein, conserved 0.0149 0.0224 0.6902
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0008
Trichomonas vaginalis chromobox protein, putative 0.0141 0.021 0.1017
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.006 0.0211
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0042
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0028 0.0098
Trypanosoma cruzi ISWI complex protein 0.0031 0.0022 0.0679
Schistosoma mansoni hypothetical protein 0.1672 0.2837 1
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0024 0.0126
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0023 0.0008 0.0168
Brugia malayi beta-lactamase 0.0149 0.0224 0.1159
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0062 0.0074 0.2295
Loa Loa (eye worm) hypothetical protein 0.0106 0.0151 0.0779
Loa Loa (eye worm) CHromoDomain protein family member 0.0035 0.0029 0.0151
Mycobacterium tuberculosis Probable lipase LipD 0.0149 0.0224 0.0235
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0022 0.0006 0.0023
Plasmodium vivax importin-beta 2, putative 0.003 0.002 0.0622
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0118
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0194 0.597
Echinococcus granulosus GPCR family 2 0.0263 0.0419 0.0444
Loa Loa (eye worm) ion channel NompC 0.0026 0.0013 0.0066
Plasmodium falciparum thioredoxin reductase 0.003 0.002 0.0629
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.003 0.002 0.0629
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0004 0.0118
Mycobacterium ulcerans hypothetical protein 0.0149 0.0224 0.0235
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0039 0.0182
Echinococcus granulosus pyruvate kinase 0.0032 0.0024 0.0026
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0028 0.0099
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative 0.0019 0.0002 0.0049
Echinococcus multilocularis neuropeptide receptor 0.011 0.0157 0.0157
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.0007 0.0035
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0022 0.0006 0.0023
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0042 0.0041 0.0043
Trypanosoma cruzi hypothetical protein, conserved 0.0149 0.0224 0.6902
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0087 0.0118 0.0123
Loa Loa (eye worm) hypothetical protein 0.0299 0.0482 0.2494
Chlamydia trachomatis phosphoglycerate kinase 0.017 0.0261 1
Echinococcus multilocularis Chromo domain 0.0023 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0321 0.0519 0.1829
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0026 0.0119
Leishmania major acetoin dehydrogenase e3 component-like protein 0.003 0.002 0.0629
Brugia malayi Protein cec-1. 0.0023 0.0008 0.0042
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.002 0.0629
Echinococcus multilocularis tar DNA binding protein 0.0266 0.0425 0.0425
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.1561 0.2645 0.2798
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0022 0.0006 0.0024
Echinococcus granulosus pyruvate kinase 0.0032 0.0024 0.0026
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0062 0.0074 0.2295
Brugia malayi TAR-binding protein 0.0266 0.0425 0.22
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0512 0.0848 0.4386
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0026 0.0119
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0135 0.0201 0.4158
Loa Loa (eye worm) hypothetical protein 0.0031 0.0021 0.0111
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0951 0.16 0.1691
Plasmodium falciparum pyruvate kinase 0.0032 0.0024 0.075
Toxoplasma gondii phosphoglycerate kinase PGKII 0.017 0.0261 0.5396
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0028 0.0128
Brugia malayi Pyruvate kinase, muscle isozyme 0.0032 0.0024 0.0126
Schistosoma mansoni smad1 5 8 and 0.0027 0.0015 0.0053
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0199 0.0309 0.0326
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0028 0.0098
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0034 0.0028 0.0028
Entamoeba histolytica hypothetical protein 0.0023 0.0008 0.018
Toxoplasma gondii hypothetical protein 0.0019 0.0002 0.0033
Trypanosoma brucei PAB1-binding protein , putative 0.0207 0.0324 1
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0026 0.081
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0039 0.0041
Entamoeba histolytica hypothetical protein 0.023 0.0363 1
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0035 0.0028 0.0028
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0123 0.0179 0.0189
Echinococcus granulosus cathepsin l cysteine peptidase 0.0034 0.0028 0.0029
Trichomonas vaginalis helicase, putative 0.0033 0.0026 0.0119
Brugia malayi cathepsin L-like precursor 0.0023 0.0008 0.0042
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0031
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0093 0.0128 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0064 0.0307
Loa Loa (eye worm) hypothetical protein 0.0079 0.0104 0.0537
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.003 0.002 0.0629
Entamoeba histolytica hypothetical protein 0.0023 0.0008 0.018
Trypanosoma brucei hypothetical protein, conserved 0.0149 0.0224 0.6902
Giardia lamblia Pyruvate kinase 0.0032 0.0024 0.0878
Loa Loa (eye worm) hypothetical protein 0.0078 0.0103 0.0531
Toxoplasma gondii hypothetical protein 0.0021 0.0004 0.0084
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0031
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0062 0.0074 0.281
Schistosoma mansoni hypothetical protein 0.154 0.261 0.9201
Mycobacterium leprae Probable lipase LipE 0.0149 0.0224 0.0841
Plasmodium vivax vivapain-2 0.0034 0.0028 0.0854
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0026 0.0119
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0042
Entamoeba histolytica hypothetical protein 0.023 0.0363 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0194 0.597
Loa Loa (eye worm) hypothetical protein 0.0047 0.0049 0.0252
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0019 0 0.0008
Entamoeba histolytica hypothetical protein 0.0024 0.001 0.0245
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0008 0.0032
Brugia malayi ion channel NompC 0.0026 0.0013 0.0066
Echinococcus granulosus beta LACTamase domain containing family member 0.0149 0.0224 0.0237
Loa Loa (eye worm) hypothetical protein 0.1145 0.1933 1
Loa Loa (eye worm) hypothetical protein 0.003 0.002 0.0104
Schistosoma mansoni ran 0.0022 0.0007 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0056 0.0065 0.0311
Echinococcus multilocularis expressed protein 0.0022 0.0006 0.0006
Mycobacterium ulcerans lipase LipD 0.0149 0.0224 0.0235
Echinococcus granulosus mixed lineage leukemia protein mll 0.0042 0.0041 0.0043
Leishmania major importin beta-1 subunit, putative 0.0024 0.001 0.0322
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0039 0.0039
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0035 0.0029 0.0029
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.003 0.002 0.0629
Schistosoma mansoni tar DNA-binding protein 0.0266 0.0425 0.1498
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.0008 0.0168
Echinococcus multilocularis neuropeptide s receptor 0.0945 0.1589 0.1589
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0141 0.021 0.021
Echinococcus multilocularis microtubule associated protein 2 0.0669 0.1116 0.1116
Brugia malayi Bromodomain containing protein 0.0089 0.0121 0.0626
Loa Loa (eye worm) hypothetical protein 0.0145 0.0218 0.1128
Echinococcus multilocularis importin subunit beta 1 0.003 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0019 0.0002 0.0006
Echinococcus granulosus thioredoxin glutathione reductase 0.0088 0.0119 0.0126
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0008 0.018
Loa Loa (eye worm) hypothetical protein 0.0149 0.0224 0.1159
Schistosoma mansoni inositol monophosphatase 0.0183 0.0283 0.0998
Schistosoma mansoni tar DNA-binding protein 0.0266 0.0425 0.1498
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.003 0.002 0.0726
Trichomonas vaginalis D-aminoacylase, putative 0.0149 0.0224 0.1087
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0039 0.1424
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0028 0.0722
Echinococcus multilocularis pyruvate kinase 0.0032 0.0024 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0028 0.0128
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0049 0.0051
Toxoplasma gondii PHD-finger domain-containing protein 0.0057 0.0066 0.1361
Loa Loa (eye worm) TAR-binding protein 0.0266 0.0425 0.22
Leishmania major cathepsin L-like protease 0.0034 0.0028 0.0854
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0063 0.0076 0.2339
Leishmania major pyruvate kinase 0.0032 0.0024 0.075
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0004 0.0002
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0079 0.0104 0.0499
Trichomonas vaginalis chromobox protein, putative 0.0141 0.021 0.1017
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0049 0.0049
Trichomonas vaginalis chromobox protein, putative 0.0085 0.0114 0.055
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0056 0.0065 0.0311
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0512 0.0848 0.0848
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0008 0.0032
Echinococcus multilocularis phosphoglycerate kinase 1 0.017 0.0261 0.0261
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0007 0.0039
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0007 0.0203
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0149 0.0224 0.0789
Brugia malayi Associated with TFs and helicases family protein 0.0023 0.0008 0.0042
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0221 0.0347 0.1308
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0042
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.002 0.0622
Trypanosoma brucei phosphoglycerate kinase 0.017 0.0261 0.8039
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0031 0.0021 0.0022
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0022 0.0006 0.0033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0035 0.0161
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0156 0.0235 0.487
Treponema pallidum phosphoglycerate kinase 0.017 0.0261 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0179 0.0188
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0004 0.0013
Loa Loa (eye worm) helicase 0.0023 0.0008 0.0042
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0022 0.0006 0.0033
Trichomonas vaginalis hypothetical protein 0.0023 0.0008 0.0032
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0004 0.0002
Onchocerca volvulus 0.0034 0.0028 0.0128
Onchocerca volvulus 0.0047 0.0049 0.023
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0022 0.0006 0.0024
Onchocerca volvulus 0.0022 0.0006 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0194 0.597
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0004 0.0004
Echinococcus granulosus jumonji domain containing protein 0.0079 0.0104 0.011
Trichomonas vaginalis importin beta-1, putative 0.0024 0.001 0.0043
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0007 0.0203
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0049 0.023
Schistosoma mansoni phosphoglycerate kinase 0.017 0.0261 0.0919
Onchocerca volvulus 0.0149 0.0224 0.1087
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0039 0.1187
Giardia lamblia NADH oxidase lateral transfer candidate 0.003 0.002 0.0726
Toxoplasma gondii thioredoxin reductase 0.0087 0.0118 0.2441
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.002 0.0629
Brugia malayi hypothetical protein 0.0023 0.0009 0.0045
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0008 0.025
Echinococcus multilocularis chromobox protein 2 0.0023 0.0008 0.0008
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0512 0.0848 0.4386
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0028 0.0128
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0008 0.018
Onchocerca volvulus 0.0022 0.0006 0.0022
Loa Loa (eye worm) Smad1 0.0027 0.0015 0.0078
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0028 0.0099
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0028 0.0128
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0039 0.0136
Schistosoma mansoni cpg binding protein 0.0147 0.0221 0.0779
Schistosoma mansoni GTP-binding protein alpha subunit 0.0022 0.0006 0.0023
Trypanosoma cruzi cysteine peptidase, putative 0.0131 0.0194 0.597
Loa Loa (eye worm) hypothetical protein 0.0023 0.0007 0.0039
Mycobacterium tuberculosis Probable hydrolase 0.0149 0.0224 0.0235
Brugia malayi SET domain containing protein 0.0032 0.0023 0.012
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.002
Plasmodium vivax pyruvate kinase, putative 0.0032 0.0024 0.075
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0004 0.0004
Brugia malayi MH1 domain containing protein 0.0027 0.0015 0.0078
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0022 0.0006 0.0007
Echinococcus multilocularis cysteine protease 0.0034 0.0028 0.0028
Schistosoma mansoni mucolipin 0.02 0.0311 0.1097
Brugia malayi Cathepsin L-like precursor 0.0034 0.0028 0.0143
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0004 0.0118
Schistosoma mansoni smad1 5 8 and 0.0027 0.0015 0.0053
Brugia malayi hypothetical protein 0.0134 0.0198 0.1026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0028 0.0128
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0007 0.0136
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0185 0.0287 0.0303
Toxoplasma gondii NADPH-glutathione reductase 0.003 0.002 0.0422
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0024 0.0111
Loa Loa (eye worm) ctsf protein 0.0034 0.0028 0.0143
Trichomonas vaginalis chromobox protein, putative 0.0085 0.0114 0.055
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0179 0.0188
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0049 0.0051
Plasmodium falciparum phd finger protein, putative 0.0057 0.0066 0.2027
Toxoplasma gondii cathepsin CPL 0.0034 0.0028 0.0574
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0004 0.0118
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative 0.0019 0.0002 0.0049
Leishmania major cathepsin L-like protease 0.0034 0.0028 0.0854
Plasmodium vivax SET domain containing protein 0.0025 0.0011 0.033
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0008 0.0032
Loa Loa (eye worm) G protein alpha subunit 3 0.0022 0.0006 0.0033
Brugia malayi Heterochromatin protein 1 0.0141 0.021 0.1085
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0056 0.0065 0.0311
Trypanosoma cruzi phosphoglycerate kinase, putative 0.017 0.0261 0.8039
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0049 0.0172
Echinococcus granulosus chromobox protein 2 0.0023 0.0008 0.0009
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0034 0.0028 0.0028
Echinococcus granulosus thymidine phosphorylase 0.5529 0.945 1
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0042 0.0041 0.0041
Schistosoma mansoni chromobox protein 0.0141 0.021 0.0739
Brugia malayi PHD-finger family protein 0.0057 0.0066 0.034
Echinococcus multilocularis thioredoxin glutathione reductase 0.0088 0.0119 0.0119
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0179 0.0275 0.0969
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0024 0.0111
Trichomonas vaginalis D-aminoacylase, putative 0.0149 0.0224 0.1087
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0028 0.0128
Onchocerca volvulus 0.0149 0.0224 0.1087
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0449 0.0739 0.2605
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0031
Schistosoma mansoni zinc finger protein 0.0059 0.007 0.0247
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0194 0.597
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0034 0.0028 0.0128
Schistosoma mansoni ap endonuclease 0.0062 0.0074 0.0262
Plasmodium vivax glutathione reductase, putative 0.0087 0.0118 0.3637
Echinococcus granulosus mothers against decapentaplegic 5 0.0027 0.0015 0.0016
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.017 0.0261 0.0274
Echinococcus granulosus expressed protein 0.0022 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.0045
Trichomonas vaginalis phosphoglycerate kinase, putative 0.017 0.0261 0.1267
Schistosoma mansoni pyruvate kinase 0.0032 0.0024 0.0086
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.019 0.0295 0.104
Giardia lamblia Histone acetyltransferase GCN5 0.012 0.0174 0.6654
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.003 0.002 0.002
Echinococcus granulosus peregrin 0.0072 0.0093 0.0098
Onchocerca volvulus 0.0034 0.0028 0.0128
Brugia malayi MH1 domain containing protein 0.0027 0.0015 0.0078
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0149 0.0224 0.1159
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0022 0.0006 0.0033
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0183 0.0283 0.8722
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0062 0.0074 0.0077
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0147 0.022 0.0233
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0063 0.0076 0.2339
Trypanosoma cruzi ISWI complex protein 0.0031 0.0022 0.0679
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0063 0.0076 0.2339
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0318 0.0514 0.1811
Echinococcus granulosus mucolipin 3 0.02 0.0311 0.0329
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.019 0.0295 0.104
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0199 0.0309 0.1164
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0073 0.0094 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0026 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0104 0.05
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0007 0.0203
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0008 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0008 0.0032
Schistosoma mansoni rotamase 0.0034 0.0028 0.0098
Brugia malayi Calcitonin receptor-like protein seb-1 0.083 0.1392 0.7205
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0194 0.597
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0022 0.0006 0.0006
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0183 0.0283 0.0298
Brugia malayi Cathepsin L-like precursor 0.0023 0.0008 0.0042
Schistosoma mansoni neuropeptide receptor 0.011 0.0157 0.0552
Onchocerca volvulus 0.0062 0.0075 0.0357
Schistosoma mansoni myo inositol monophosphatase 0.0019 0.0002 0.0006
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.003 0.002 0.002
Schistosoma mansoni myst-related protein 0.0021 0.0005 0.0018
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0164 0.025 0.094
Leishmania major myo-inositol-1 phosphatase, putative 0.0019 0.0002 0.0049
Brugia malayi Cathepsin L-like precursor 0.0034 0.0028 0.0143
Schistosoma mansoni pyruvate kinase 0.0032 0.0024 0.0086
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.017 0.0261 0.92
Loa Loa (eye worm) hypothetical protein 0.0032 0.0024 0.0126
Onchocerca volvulus 0.0149 0.0224 0.1087
Trichomonas vaginalis ran, putative 0.0022 0.0007 0.0024
Trypanosoma brucei phosphoglycerate kinase 0.0063 0.0076 0.2339
Schistosoma mansoni hypothetical protein 0.0263 0.0419 0.1477
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.0007 0.0035
Echinococcus granulosus cathepsin L cysteine proteinase 0.0034 0.0028 0.0029
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0022 0.0006 0.0007
Schistosoma mansoni cpg binding protein 0.0159 0.0242 0.0854
Echinococcus multilocularis Smad4 0.0027 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0149 0.0224 0.1159
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.002 0.0629
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0022 0.0006 0.0023
Leishmania major DNA polymerase eta, putative 0.0021 0.0004 0.0118
Trypanosoma cruzi phosphoglycerate kinase, putative 0.017 0.0261 0.8039
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0073 0.0256
Loa Loa (eye worm) MH2 domain-containing protein 0.0397 0.065 0.3363
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0027 0.0014 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0028 0.0128
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.001 0.0043
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0221 0.0347 0.0366
Echinococcus multilocularis cpg binding protein 0.0159 0.0242 0.0242
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0022 0.0006 0.0023
Brugia malayi beta-lactamase family protein 0.0149 0.0224 0.1159
Plasmodium falciparum heterochromatin protein 1 0.0023 0.0008 0.025
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0051 0.0056 0.0056
Toxoplasma gondii histone lysine methyltransferase SET1 0.03 0.0483 1
Trypanosoma cruzi hypothetical protein, conserved 0.0149 0.0224 0.6902
Loa Loa (eye worm) hypothetical protein 0.0178 0.0274 0.1416
Echinococcus multilocularis GPCR, family 2 0.0263 0.0419 0.0419
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0028 0.0128
Brugia malayi latrophilin 2 splice variant baaae 0.0567 0.0942 0.4874
Chlamydia trachomatis pyruvate kinase 0.0032 0.0024 0.0878
Entamoeba histolytica hypothetical protein 0.0021 0.0005 0.0097
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0056 0.0065 0.0311
Onchocerca volvulus 0.0147 0.0221 0.1073
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0022 0.0006 0.0033
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.006 0.006
Loa Loa (eye worm) fibroinase 0.0034 0.0028 0.0143
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0032 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0124 0.0181 0.0939
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0024 0.0111
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0056 0.0065 0.0311
Loa Loa (eye worm) hypothetical protein 0.0097 0.0135 0.0699
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.003 0.002 0.0629
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0007 0.0163
Loa Loa (eye worm) MH2 domain-containing protein 0.0027 0.0015 0.0078
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0183 0.0283 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0062 0.0074 0.2295
Echinococcus granulosus histone acetyltransferase KAT2B 0.0432 0.0709 0.0751
Onchocerca volvulus Huntingtin homolog 0.0124 0.0181 0.0879
Echinococcus multilocularis snurportin 1 0.0321 0.0519 0.0519
Brugia malayi jmjC domain containing protein 0.0081 0.0107 0.0555
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0028 0.0128
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0022 0.0006 0.0024
Loa Loa (eye worm) heterochromatin protein 1 0.0141 0.021 0.1085
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0028 0.0128
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.019 0.0295 0.0295
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.001 0.0043
Schistosoma mansoni cathepsin F (C01 family) 0.0023 0.0008 0.0029
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0093 0.0128 0.0136
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0031
Brugia malayi CXXC zinc finger family protein 0.0147 0.0221 0.1144
Brugia malayi M-phase phosphoprotein, mpp8 0.0023 0.0008 0.0042
Loa Loa (eye worm) hypothetical protein 0.0567 0.0942 0.4874
Schistosoma mansoni Smad4 0.0027 0.0015 0.0053
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.012 0.0174 0.5369
Trichomonas vaginalis set domain proteins, putative 0.1212 0.2047 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0263 0.0419 0.0419
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0512 0.0848 0.2988
Trichomonas vaginalis penicillin-binding protein, putative 0.0149 0.0224 0.1087
Echinococcus granulosus muscleblind protein 0.0145 0.0218 0.0231
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0034 0.0028 0.0854
Echinococcus multilocularis pyruvate kinase 0.0026 0.0013 0.0013
Echinococcus multilocularis G protein coupled receptor 139 0.011 0.0157 0.0157
Toxoplasma gondii LsmAD domain-containing protein 0.0207 0.0324 0.6712
Brugia malayi follicle stimulating hormone receptor 0.0243 0.0386 0.1996
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0033
Plasmodium vivax vivapain-2 0.0034 0.0028 0.0854
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.002 0.0629
Schistosoma mansoni hypothetical protein 0.0057 0.0066 0.0232
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0266 0.0425 0.22
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0042
Schistosoma mansoni tar DNA-binding protein 0.0266 0.0425 0.1498
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0008 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0118
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.023 0.0363 0.0363
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0026 0.0119
Schistosoma mansoni hypothetical protein 0.0263 0.0419 0.1477
Schistosoma mansoni hypothetical protein 0.0019 0 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0056 0.0065 0.0311
Echinococcus multilocularis thymidine phosphorylase 0.5529 0.945 0.945
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0183 0.0283 0.8722
Brugia malayi hypothetical protein 0.0207 0.0324 0.1679
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0027 0.0016 0.0486
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0141 0.021 0.0222
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0063 0.0076 0.2339
Mycobacterium ulcerans esterase/lipase LipP 0.0149 0.0224 0.0235
Onchocerca volvulus 0.0034 0.0028 0.0128
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0118
Brugia malayi PHD-finger family protein 0.007 0.0089 0.0459
Toxoplasma gondii ABC1 family protein 0.0149 0.0224 0.4633
Schistosoma mansoni jumonji domain containing protein 0.0147 0.0221 0.078
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0039 0.0182
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0 0.0008
Brugia malayi beta-lactamase family protein 0.0149 0.0224 0.1159
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0004 0.0118
Trypanosoma brucei inositol polyphosphate 1-phosphatase, putative 0.0019 0.0002 0.0049
Loa Loa (eye worm) jmjC domain-containing protein 0.0117 0.0169 0.0876
Echinococcus granulosus snurportin 1 0.0321 0.0519 0.0549
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0578 0.0959 0.0959
Loa Loa (eye worm) latrophilin receptor protein 2 0.0263 0.0419 0.2169
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0054 0.0062 0.0062
Mycobacterium ulcerans phosphoglycerate kinase 0.017 0.0261 0.0274
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0 0.0012
Loa Loa (eye worm) hypothetical protein 0.0149 0.0224 0.1159
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0039 0.1187
Echinococcus granulosus PHD finger protein rhinoceros 0.0057 0.0066 0.007
Brugia malayi RNA, U transporter 1 0.0085 0.0115 0.0596
Onchocerca volvulus 0.0034 0.0028 0.0128
Toxoplasma gondii aldehyde dehydrogenase 0.0123 0.0179 0.3699
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0194 0.597
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.006 0.0063
Leishmania major trypanothione reductase 0.0087 0.0118 0.3637
Echinococcus multilocularis cathepsin L cysteine protease 0.0034 0.0028 0.0028
Leishmania major hypothetical protein, conserved 0.0031 0.0022 0.0679
Echinococcus granulosus Chromo domain 0.0023 0.0008 0.0009
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.003 0.002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0033
Onchocerca volvulus 0.0022 0.0006 0.0023
Schistosoma mansoni microtubule-associated protein tau 0.0669 0.1116 0.3933
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0049 0.0252
Trichomonas vaginalis D-aminoacylase, putative 0.0149 0.0224 0.1087
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0123 0.0179 0.5511
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0022 0.0006 0.0033
Brugia malayi SET domain containing protein 0.0021 0.0005 0.0025
Loa Loa (eye worm) histone methyltransferase 0.0051 0.0056 0.0292
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0022 0.0006 0.0033
Mycobacterium ulcerans beta-lactamase 0.0149 0.0224 0.0235
Brugia malayi Cathepsin L-like precursor 0.0023 0.0008 0.0042
Echinococcus multilocularis mothers against decapentaplegic 5 0.0027 0.0015 0.0015
Brugia malayi exodeoxyribonuclease III family protein 0.0062 0.0074 0.0385
Echinococcus granulosus 3'2'5' bisphosphate nucleotidase 1 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0008
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.0026 0.0544
Leishmania major cathepsin L-like protease 0.0034 0.0028 0.0854
Echinococcus multilocularis expressed protein 0.0034 0.0028 0.0028
Brugia malayi Importin beta-1 subunit 0.003 0.002 0.0104
Entamoeba histolytica hypothetical protein 0.023 0.0363 1
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.002 0.0629
Trypanosoma cruzi cysteine peptidase, putative 0.0034 0.0028 0.0854
Trypanosoma cruzi cysteine peptidase, putative 0.0131 0.0194 0.597
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0118
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0149 0.0224 0.0235
Toxoplasma gondii phosphoglycerate kinase PGKI 0.017 0.0261 0.5396
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0007 0.0192
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.002 0.0629
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0039 0.1187
Trypanosoma cruzi cruzipain precursor, putative 0.0131 0.0194 0.597
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0028 0.0128
Plasmodium vivax SET domain protein, putative 0.0156 0.0235 0.7256
Brugia malayi Valyl-tRNA synthetase 0.0023 0.0008 0.0042
Brugia malayi Coelomocyte uptake defective protein 5 0.02 0.0311 0.161
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0039 0.0199
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0056 0.0065 0.0311
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0022 0.0006 0.0023
Loa Loa (eye worm) pigment dispersing factor receptor c 0.083 0.1392 0.7205
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.006 0.0063
Echinococcus multilocularis muscleblind protein 0.0145 0.0218 0.0218
Echinococcus granulosus chromobox protein 1 0.0141 0.021 0.0222
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.002 0.052
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.002 0.0629
Trypanosoma brucei trypanothione reductase 0.0087 0.0118 0.3637
Loa Loa (eye worm) acetyltransferase 0.0449 0.0739 0.3824
Trypanosoma cruzi trypanothione reductase, putative 0.0087 0.0118 0.3637
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0008 0.0032
Schistosoma mansoni hypothetical protein 0.0296 0.0476 0.1679
Leishmania major DNA polymerase kappa, putative 0.0021 0.0004 0.0118
Schistosoma mansoni tar DNA-binding protein 0.0266 0.0425 0.1498
Brugia malayi F/Y-rich N-terminus family protein 0.0073 0.0094 0.0485
Loa Loa (eye worm) transcription factor SMAD2 0.0397 0.065 0.3363
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0183 0.0283 0.7778
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0034 0.0028 0.0128
Trichomonas vaginalis penicillin-binding protein, putative 0.0149 0.0224 0.1087
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0008 0.0032
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0057 0.0066 0.0232
Trichomonas vaginalis esterase, putative 0.0149 0.0224 0.1087
Schistosoma mansoni jumonji/arid domain-containing protein 0.0081 0.0107 0.0378
Brugia malayi MH2 domain containing protein 0.0027 0.0015 0.0078
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0022 0.0006 0.0033
Echinococcus multilocularis neuropeptide receptor A26 0.0945 0.1589 0.1589
Onchocerca volvulus Cathepsin F homolog 0.0034 0.0028 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0104 0.05
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.002 0.0629
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.001 0.0322
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0004 0.0002
Leishmania major phosphoglycerate kinase C, glycosomal 0.017 0.0261 0.8039
Schistosoma mansoni bromodomain containing protein 0.0028 0.0017 0.0059
Plasmodium falciparum phosphoglycerate kinase 0.017 0.0261 0.8039
Loa Loa (eye worm) jmjC domain-containing protein 0.0081 0.0107 0.0555
Onchocerca volvulus 0.0022 0.0006 0.0023
Mycobacterium tuberculosis Conserved protein 0.0149 0.0224 0.0235
Brugia malayi chromobox protein homolog 3 0.0079 0.0104 0.0537
Loa Loa (eye worm) hypothetical protein 0.0149 0.0224 0.1159
Brugia malayi RNA recognition motif domain containing protein 0.0266 0.0425 0.22
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0024 0.075
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0512 0.0848 0.0848
Brugia malayi Pre-SET motif family protein 0.0156 0.0235 0.1218
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0026 0.0119
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.017 0.0261 0.0981
Echinococcus granulosus methyl CpG binding domain protein 2 0.0035 0.0028 0.003
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0022 0.0006 0.0033
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0039 0.0041
Onchocerca volvulus 0.1212 0.2048 1
Leishmania major cathepsin L-like protease 0.0131 0.0194 0.597
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0063 0.0076 0.2339
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0022 0.0006 0.0024
Onchocerca volvulus 0.0022 0.0006 0.0022
Mycobacterium tuberculosis Probable esterase LipL 0.0149 0.0224 0.0235
Echinococcus multilocularis dnaJ subfamily B 0.1672 0.2837 0.2837
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.0028 0.0143
Loa Loa (eye worm) beta-lactamase 0.0149 0.0224 0.1159
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0243 0.0386 0.1996
Leishmania major cathepsin L-like protease 0.0131 0.0194 0.597
Schistosoma mansoni inositol monophosphatase 0.0183 0.0283 0.0998
Loa Loa (eye worm) hypothetical protein 0.0034 0.0028 0.0143
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.002 0.0622
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0062 0.0074 0.2471
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0008 0.025
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0196 0.0305 0.0305
Plasmodium falciparum thioredoxin reductase 0.0087 0.0118 0.3637
Plasmodium vivax heterochromatin protein 1, putative 0.0023 0.0008 0.025
Mycobacterium tuberculosis Probable dehydrogenase 0.0199 0.0309 0.0326
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0 0.0012
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0023 0.0008 0.0008
Brugia malayi AF-10 protein 0.0019 0 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0026 0.0119
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0149 0.0224 0.0235
Plasmodium falciparum glutathione reductase 0.003 0.002 0.0629
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0022 0.0006 0.0033
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.0008 0.0029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0194 0.597
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0004 0.0118
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0031
Trichomonas vaginalis phosphoglycerate kinase, putative 0.017 0.0261 0.1267
Plasmodium vivax hypothetical protein, conserved 0.0149 0.0224 0.6902
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0007 0.0203
Treponema pallidum exodeoxyribonuclease (exoA) 0.0062 0.0074 0.2248
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0007 0.0034
Schistosoma mansoni smad1 5 8 and 0.0027 0.0015 0.0053
Leishmania major phosphoglycerate kinase B, cytosolic 0.017 0.0261 0.8039
Trypanosoma brucei pyruvate kinase 1 0.0032 0.0024 0.075
Echinococcus granulosus cpg binding protein 0.0159 0.0242 0.0256
Giardia lamblia DINP protein human, muc B family 0.0021 0.0004 0.0086
Trypanosoma brucei pyruvate kinase 1, putative 0.0032 0.0024 0.075
Schistosoma mansoni ap endonuclease 0.0062 0.0074 0.0262
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0004 0.0011
Echinococcus multilocularis mucolipin 3 0.02 0.0311 0.0311
Brugia malayi G-protein alpha subunit 0.0022 0.0006 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0028 0.0128
Mycobacterium tuberculosis Probable reductase 0.0199 0.0309 0.0326
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0008 0.018
Loa Loa (eye worm) bromodomain containing protein 0.0047 0.0049 0.0253
Plasmodium falciparum ataxin-2 like protein, putative 0.0207 0.0324 1
Onchocerca volvulus Alhambra homolog 0.0057 0.0066 0.0314
Loa Loa (eye worm) inositol-1 0.0183 0.0283 0.1464
Plasmodium vivax ataxin-2 like protein, putative 0.0207 0.0324 1
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.002 0.0418
Echinococcus granulosus cathepsin l1 0.0023 0.0008 0.0009
Brugia malayi hypothetical protein 0.0124 0.0181 0.0939
Plasmodium falciparum ataxin-2 like protein, putative 0.0207 0.0324 1
Echinococcus granulosus zinc finger protein 0.0059 0.007 0.0074
Brugia malayi Inositol monophosphatase family protein 0.0019 0.0002 0.0008
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0062 0.0074 0.2295
Schistosoma mansoni hypothetical protein 0.023 0.0363 0.1281
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0008 0.0032
Trypanosoma brucei unspecified product 0.0021 0.0004 0.0118
Loa Loa (eye worm) hypothetical protein 0.0124 0.0181 0.0939
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0004 0.0004
Plasmodium falciparum cysteine proteinase falcipain 3 0.0034 0.0028 0.0854
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0031
Brugia malayi jmjC domain containing protein 0.0185 0.0287 0.1484
Entamoeba histolytica acetyltransferase, GNAT family 0.012 0.0174 0.4768
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1065 0.1796 0.9292
Echinococcus multilocularis beta LACTamase domain containing family member 0.0149 0.0224 0.0224
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0022 0.0006 0.0023
Mycobacterium leprae Probable pyruvate kinase PykA 0.0032 0.0024 0.0086
Leishmania major cathepsin L-like protease 0.0034 0.0028 0.0854
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0007 0.0034
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0054 0.0062 0.0218
Echinococcus granulosus fetal alzheimer antigen falz 0.0054 0.0062 0.0065
Echinococcus multilocularis lysine specific demethylase 5A 0.0069 0.0086 0.0086
Echinococcus granulosus dna polymerase eta 0.0021 0.0004 0.0004
Loa Loa (eye worm) glutathione reductase 0.0087 0.0118 0.0611
Brugia malayi Pyruvate kinase, M2 isozyme 0.0032 0.0024 0.0126
Echinococcus granulosus Chromobox protein 3 0.0023 0.0008 0.0009
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0062 0.0074 0.2295
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0149 0.0224 0.0235
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0049 0.0172
Onchocerca volvulus 0.0022 0.0006 0.0022
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.002 0.052
Brugia malayi Inositol-1 0.0183 0.0283 0.1464
Loa Loa (eye worm) hypothetical protein 0.0207 0.0324 0.1679
Mycobacterium tuberculosis Conserved protein 0.0149 0.0224 0.0235
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0321 0.0519 0.2685
Entamoeba histolytica Ran family GTPase 0.0022 0.0007 0.0138
Plasmodium vivax phosphoglycerate kinase, putative 0.017 0.0261 0.8039
Brugia malayi ion channel NompC 0.0022 0.0007 0.0034
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.5529 0.945 1
Mycobacterium ulcerans thymidine phosphorylase 0.5529 0.945 1
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0022 0.0006 0.0033
Brugia malayi MH2 domain containing protein 0.0027 0.0015 0.0078
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0063 0.0076 0.2339
Trichomonas vaginalis mercuric reductase, putative 0.003 0.002 0.0092
Onchocerca volvulus Cathepsin L homolog 0.0034 0.0028 0.0128
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0512 0.0848 0.0897
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0183 0.0283 0.1376
Brugia malayi Cathepsin L-like precursor 0.0034 0.0028 0.0143
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0118
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.003 0.002 0.002
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0023 0.0008 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0026 0.0119
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0024 0.0126
Loa Loa (eye worm) RNA binding protein 0.0266 0.0425 0.22
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0062 0.0074 0.0074
Onchocerca volvulus 0.0034 0.0028 0.0128
Echinococcus multilocularis 3'(2'),5' bisphosphate nucleotidase 1 0.0019 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0019 0.0002 0.0006
Echinococcus multilocularis jumonji domain containing protein 0.0079 0.0104 0.0104
Trypanosoma brucei phosphoglycerate kinase, putative 0.0063 0.0076 0.2339
Echinococcus multilocularis cysteine protease 0.0034 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0062 0.0075 0.0386
Echinococcus granulosus inositol monophosphatase 1 0.0183 0.0283 0.0299
Schistosoma mansoni chromobox protein 0.0023 0.0008 0.0029
Trypanosoma brucei phosphoglycerate kinase 0.017 0.0261 0.8039
Echinococcus multilocularis inositol monophosphatase 1 0.0183 0.0283 0.0283
Schistosoma mansoni hypothetical protein 0.0023 0.0008 0.0029
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0123 0.0179 0.0179
Brugia malayi Cathepsin L-like precursor 0.0034 0.0028 0.0143
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0004 0.0118
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0149 0.0224 0.1159
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0024 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0008 0.0032
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0008 0.0032
Onchocerca volvulus 0.0023 0.0008 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0028 0.0128
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0022 0.0006 0.0033
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.006 0.0309
Echinococcus granulosus phosphoglycerate kinase 1 0.017 0.0261 0.0276
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0022 0.0006 0.0023
Schistosoma mansoni importin beta-1 0.003 0.002 0.0071
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0035 0.0029 0.0103
Echinococcus multilocularis chromobox protein 1 0.0141 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0041 0.0039 0.0199
Schistosoma mansoni chromobox protein 0.0141 0.021 0.0739
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0221 0.0347 0.0366
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0512 0.0848 0.2988
Loa Loa (eye worm) hypothetical protein 0.0144 0.0215 0.1115
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0022 0.0006 0.0024
Onchocerca volvulus 0.0023 0.0008 0.0032
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0031
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0007 0.0203
Loa Loa (eye worm) hypothetical protein 0.017 0.0261 0.135
Trichomonas vaginalis ap endonuclease, putative 0.0062 0.0074 0.0356
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0004 0.0118
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0056 0.0065 0.0311
Loa Loa (eye worm) hypothetical protein 0.0149 0.0224 0.1159
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0123 0.0179 0.0188
Echinococcus granulosus histone acetyltransferase KAT2B 0.0135 0.0201 0.0213
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0008 0.0032
Echinococcus granulosus geminin 0.154 0.261 0.2762
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0164 0.025 0.0263
Trichomonas vaginalis rotamase, putative 0.0034 0.0028 0.0128
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0023 0.0008 0.0042
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0183 0.0283 0.5854
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.0008 0.0029
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0199 0.0309 0.0326
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0199 0.0309 0.0326
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0033
Brugia malayi Bromodomain containing protein 0.0172 0.0263 0.1363
Echinococcus multilocularis inositol monophosphatase 0.0019 0.0002 0.0002
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0062 0.0074 0.0077
Schistosoma mansoni hypothetical protein 0.0263 0.0419 0.1477
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0026 0.081
Loa Loa (eye worm) MBCTL1 0.0053 0.006 0.0309
Giardia lamblia Protein 21.1 0.0022 0.0006 0.017
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.002 0.0629
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0022 0.0006 0.0023
Toxoplasma gondii exonuclease III APE 0.0062 0.0074 0.154
Onchocerca volvulus 0.0034 0.0028 0.0128
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0179 0.0188
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0022 0.0006 0.0024
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0022 0.0006 0.0024
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0049 0.0049
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0004 0.002
Brugia malayi mbt repeat family protein 0.0047 0.0049 0.0252
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0194 0.597
Schistosoma mansoni hypothetical protein 0.0567 0.0942 0.332
Schistosoma mansoni hypothetical protein 0.0031 0.0022 0.0078
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.002 0.0629
Schistosoma mansoni pap-inositol-14-phosphatase 0.0019 0.0002 0.0006
Brugia malayi Muscleblind-like protein 0.0145 0.0218 0.1128
Echinococcus granulosus tar DNA binding protein 0.0266 0.0425 0.045
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0179 0.063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0008 0.0032
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0263 0.0419 0.0444
Mycobacterium tuberculosis Probable oxidoreductase 0.0221 0.0347 0.0366
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0118
Echinococcus multilocularis smad 0.0027 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.019 0.0295 0.1526
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0028 0.0128
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0194 0.597
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0033
Echinococcus multilocularis PHD finger protein rhinoceros 0.0057 0.0066 0.0066
Brugia malayi acetyltransferase, GNAT family protein 0.0449 0.0739 0.3824
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0004 0.002
Brugia malayi Cathepsin L-like precursor 0.0034 0.0028 0.0143
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0034 0.0028 0.0854
Echinococcus multilocularis cathepsin L cysteine protease 0.0034 0.0028 0.0028
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.0028 0.0143
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0028 0.0128
Brugia malayi Bromodomain containing protein 0.0072 0.0093 0.048
Toxoplasma gondii PHD-finger domain-containing protein 0.0057 0.0066 0.1361
Mycobacterium tuberculosis Conserved protein 0.0149 0.0224 0.0235
Onchocerca volvulus 0.0299 0.0482 0.2348
Giardia lamblia PHD finger protein 15 0.0057 0.0066 0.2476
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.002 0.0629
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0028 0.0128
Brugia malayi RNA binding protein 0.0266 0.0425 0.22
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1145 0.1933 1
Brugia malayi Smad1 0.0027 0.0015 0.0078
Loa Loa (eye worm) PHD-finger family protein 0.0057 0.0066 0.034
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0156 0.0235 0.083
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0042
Leishmania major GTP-binding protein, putative 0.0022 0.0007 0.0203
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.003 0.002 0.0629
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0008 0.0032
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0185 0.0287 0.0287
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.003 0.002 0.0629
Mycobacterium ulcerans pyruvate kinase 0.0032 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0145 0.0218 0.1128
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0135 0.0201 0.6195
Echinococcus granulosus dna polymerase kappa 0.0021 0.0004 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0008 0.0032
Trypanosoma cruzi PAB1-binding protein , putative 0.0207 0.0324 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.002 0.0629
Mycobacterium ulcerans flavoprotein disulfide reductase 0.003 0.002 0.002
Schistosoma mansoni SET domain protein 0.0021 0.0005 0.0017
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0049 0.0172
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0022 0.0006 0.0006
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0022 0.0006 0.0007
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0051 0.0056 0.006
Echinococcus granulosus chromobox protein 1 0.0141 0.021 0.0222
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0022 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0004 0.0118
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0512 0.0848 0.2988
Schistosoma mansoni DNA polymerase eta 0.0021 0.0004 0.0013
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0135 0.0201 0.0975
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0039 0.1187
Onchocerca volvulus Cathepsin L homolog 0.0034 0.0028 0.0128
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0022 0.0006 0.0007
Onchocerca volvulus 0.0179 0.0275 0.1336
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0057 0.0066 0.034
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0199 0.0309 0.0326
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0183 0.0283 0.8722
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0027 0.0015 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.0194 0.597
Toxoplasma gondii pyruvate kinase PyK1 0.0032 0.0024 0.0504
Schistosoma mansoni hypothetical protein 0.0093 0.0128 0.0452
Loa Loa (eye worm) hypothetical protein 0.0053 0.006 0.0309
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0039 0.018
Trichomonas vaginalis inositol monophosphatase, putative 0.0183 0.0283 0.1376
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0042
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0062 0.0074 0.0079
Schistosoma mansoni mucolipin 0.0183 0.0282 0.0996
Brugia malayi PHD-finger family protein 0.0031 0.0021 0.0111
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0007 0.0007
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0022 0.0006 0.0006
Brugia malayi hypothetical protein 0.023 0.0363 0.188
Loa Loa (eye worm) hypothetical protein 0.0149 0.0224 0.1159
Schistosoma mansoni bromodomain containing protein 0.0148 0.0223 0.0784
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0179 0.063
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0008 0.0032
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0135 0.0201 0.4158
Onchocerca volvulus Huntingtin homolog 0.0124 0.0181 0.0879
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0024 0.0111
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.003 0.002 0.0106
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0004 0.0118
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0023 0.0008 0.025
Trypanosoma cruzi myo-inositol-1 phosphatase, putative 0.0019 0.0002 0.0049
Brugia malayi Cathepsin L-like precursor 0.0034 0.0028 0.0143
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0149 0.0224 0.0789
Echinococcus granulosus TGF beta signal transducer SmadC 0.0027 0.0015 0.0016
Schistosoma mansoni phosphoglycerate kinase 0.017 0.0261 0.0919
Schistosoma mansoni hypothetical protein 0.0263 0.0419 0.1477
Entamoeba histolytica cysteine protease, putative 0.0034 0.0028 0.0722
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0022 0.0006 0.0024
Schistosoma mansoni transcription factor LCR-F1 0.023 0.0363 0.1281
Brugia malayi hypothetical protein 0.0022 0.0006 0.0033
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0022 0.0006 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0008 0.0032
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0196 0.0305 0.0323
Trichomonas vaginalis ap endonuclease, putative 0.0062 0.0074 0.0356
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.023 0.0363 0.0385
Entamoeba histolytica hypothetical protein 0.023 0.0363 1
Echinococcus multilocularis Chromobox protein 3 0.0023 0.0008 0.0008
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0022 0.0006 0.0007
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0028 0.0143
Trypanosoma cruzi major cysteine proteinase, putative 0.0103 0.0146 0.4486
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0039 0.0136
Trichomonas vaginalis rotamase, putative 0.0034 0.0026 0.0121
Leishmania major cathepsin L-like protease 0.0131 0.0194 0.597
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0004 0.0118
Echinococcus multilocularis chromobox protein 1 0.0141 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0031
Plasmodium falciparum importin beta, putative 0.003 0.002 0.0622
Plasmodium vivax hypothetical protein, conserved 0.0057 0.0066 0.2027
Leishmania major cysteine peptidase A (CPA) 0.0034 0.0028 0.0854
Mycobacterium tuberculosis Probable lipase LipE 0.0149 0.0224 0.0235

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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