Detailed information for compound 586820

Basic information

Technical information
  • TDR Targets ID: 586820
  • Name: 3-[[2-[[6-amino-2-[[2-amino-3-(1H-imidazol-5- yl)propanoyl]amino]hexanoyl]amino]-3-hydroxy- butanoyl]amino]-4-[[2-[[1-benzyl-2-[[1-[[2-[[ 1-[(1-carbamoyl-3-methylsulfanyl-propyl)carba moyl]-3-methyl-butyl]amino]-2-oxo-ethyl]carba moyl]-2-methyl-propyl]amino]-2-oxo-ethyl]amin o]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-4-oxo -butanoic acid
  • MW: 1133.32 | Formula: C50H80N14O14S
  • H donors: 16 H acceptors: 15 LogP: -4.82 Rotable bonds: 46
    Rule of 5 violations (Lipinski): 4
  • SMILES: NCCCCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N)CCSC)CC(C)C)C(C)C)Cc1ccccc1)CO)CC(=O)O)C(O)C)NC(=O)C(Cc1[nH]cnc1)N
  • InChi: 1S/C50H80N14O14S/c1-26(2)18-34(45(73)58-32(42(53)70)15-17-79-6)57-38(67)23-55-49(77)40(27(3)4)63-47(75)35(19-29-12-8-7-9-13-29)60-48(76)37(24-65)62-46(74)36(21-39(68)69)61-50(78)41(28(5)66)64-44(72)33(14-10-11-16-51)59-43(71)31(52)20-30-22-54-25-56-30/h7-9,12-13,22,25-28,31-37,40-41,65-66H,10-11,14-21,23-24,51-52H2,1-6H3,(H2,53,70)(H,54,56)(H,55,77)(H,57,67)(H,58,73)(H,59,71)(H,60,76)(H,61,78)(H,62,74)(H,63,75)(H,64,72)(H,68,69)
  • InChiKey: HEAUFJZALFKPBA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[[2-[[6-amino-2-[[2-amino-3-(1H-imidazol-5-yl)-1-oxopropyl]amino]-1-oxohexyl]amino]-3-hydroxy-1-oxobutyl]amino]-4-[[2-[[1-benzyl-2-[[1-[[[2-[[1-[[[1-carbamoyl-3-(methylthio)propyl]amino]-oxomethyl]-3-methylbutyl]amino]-2-oxoethyl]amino]-oxomethyl]-2-methylpropyl]amino]-2-oxoethyl]amino]-1-(hydroxymethyl)-2-oxoethyl]amino]-4-oxobutanoic acid
  • 3-[[2-[[6-azanyl-2-[[2-azanyl-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]-3-hydroxy-butanoyl]amino]-4-[[1-[[1-[[1-[[2-[[1-[(1-azanyl-4-methylsulfanyl-1-oxo-butan-2-yl)amino]-4-methyl-1-oxo-pentan-2-yl]amino]-2-oxo-ethyl]amino]-3-methyl-1-oxo-butan-2-yl]amino]-1-oxo-3-phenyl-propan-2-yl]amino]-3-hydroxy-1-oxo-propan-2-yl]amino]-4-oxo-butanoic acid
  • 3-[[2-[[6-amino-2-[[2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]-3-hydroxy-butanoyl]amino]-4-[[2-[[1-benzyl-2-[[1-[[2-[[1-[[1-carbamoyl-3-(methylthio)propyl]carbamoyl]-3-methyl-butyl]amino]-2-keto-ethyl]carbamoyl]-2-methyl-propyl]amino]-2-keto-ethyl]amino]-2-keto-1-methylol-ethyl]amino]-4-keto-butyric acid
  • 3-[[2-[[6-amino-2-[[2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]-3-hydroxybutanoyl]amino]-4-[[1-[[1-[[1-[[2-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
  • Neurokinin A
  • 3-[[2-[[6-amino-2-[[2-amino-3-(3H-imidazol-4-yl)propanoyl]amino]hexanoyl]amino]-3-hydroxybutanoyl]amino]-4-[[1-[[1-[[1-[[2-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
  • 3-[[2-[[6-amino-2-[[2-amino-3-(3H-imidazol-4-yl)propanoyl]amino]hexanoyl]amino]-3-hydroxy-butanoyl]amino]-4-[[2-[[2-[[1-[[2-[[1-[(1-carbamoyl-3-methylsulfanyl-propyl)carbamoyl]-3-methyl-butyl]amino]-2-oxo-ethyl]carbamoyl]-2-methyl-propyl]amino]-2-oxo-1-(phenylmethyl)ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-4-oxo-butanoic acid
  • 3-[[2-[[6-amino-2-[[2-amino-3-(3H-imidazol-4-yl)-1-oxopropyl]amino]-1-oxohexyl]amino]-3-hydroxy-1-oxobutyl]amino]-4-[[2-[[2-[[1-[[[2-[[1-[[[1-carbamoyl-3-(methylthio)propyl]amino]-oxomethyl]-3-methylbutyl]amino]-2-oxoethyl]amino]-oxomethyl]-2-methylpropyl]amino]-2-oxo-1-(phenylmethyl)ethyl]amino]-1-(hydroxymethyl)-2-oxoethyl]amino]-4-oxobutanoic acid
  • 3-[[2-[[6-amino-2-[[2-amino-3-(3H-imidazol-4-yl)propanoyl]amino]hexanoyl]amino]-3-hydroxy-butanoyl]amino]-4-[[2-[[1-(benzyl)-2-[[1-[[2-[[1-[[1-carbamoyl-3-(methylthio)propyl]carbamoyl]-3-methyl-butyl]amino]-2-keto-ethyl]carbamoyl]-2-methyl-propyl]amino]-2-keto-ethyl]amino]-2-keto-1-methylol-ethyl]amino]-4-keto-butyric acid
  • 3-[[2-[[6-amino-2-[[2-amino-3-(3H-imidazol-4-yl)propanoyl]amino]hexanoyl]amino]-3-hydroxy-butanoyl]amino]-4-[[1-[[1-[[1-[[2-[[1-[(1-amino-4-methylsulfanyl-1-oxo-butan-2-yl)amino]-4-methyl-1-oxo-pentan-2-yl]amino]-2-oxo-ethyl]amino]-3-methyl-1-oxo-butan-2-yl]amino]-1-oxo-3-phenyl-propan-2-yl]amino]-3-hydroxy-1-oxo-propan-2-yl]amino]-4-oxo-butanoic acid
  • 144747-18-2
  • 86933-74-6
  • 88507-24-8
  • Neurokinin alpha (porcine)
  • Neuromedin L
  • Neuromedin L (pig spinal cord)
  • Porcine neurokinin A
  • Substance K
  • N4267_SIGMA
  • alpha-Neurokinin
  • Kassinin, 1-de-L-aspartic acid-2-de-L-valine-3-L-histidine-5-L-threonine-7-L-serine-
  • L-Methioninamide, L-histidyl-L-lysyl-L-threonyl-L-alpha-aspartyl-L-seryl-L-phenylalanyl-L-valylglycyl-L-leucyl-
  • Neurokinin A (Python molurus)
  • Neurokinin A (alligator)
  • Neurokinin A (pig spinal cord)
  • Neurokinin A (swine spinal cord)
  • Neurokinin alpha
  • Neurokinin alpha (pig spinal cord)

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0086 0.0131 0.0304
Onchocerca volvulus 0.0119 0.0193 0.0185
Onchocerca volvulus Neurogenic locus notch homolog 0.0326 0.0582 0.0574
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0022 0.001 0.0023
Echinococcus multilocularis transfer RNA-Phe 0.0021 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Toxoplasma gondii kringle domain-containing protein 0.0309 0.0549 0.1272
Loa Loa (eye worm) hypothetical protein 0.0216 0.0374 0.0588
Echinococcus granulosus neuropeptides capa receptor 0.0026 0.0018 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.001 0.0235
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0071 0.0102 0.0154
Echinococcus granulosus a disintegrin and metalloproteinase with 0.071 0.1302 0.1436
Entamoeba histolytica cysteine proteinase, putative 0.0022 0.001 0.1435
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0018 0.0054
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0144 0.0239 0.0733
Onchocerca volvulus 0.0026 0.0018 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0126
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0017 0.0039
Echinococcus multilocularis protein jagged 1 0.0326 0.0582 0.0642
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Schistosoma mansoni hypothetical protein 0.0026 0.0018 0.0054
Echinococcus granulosus Phosphotidylinositol phosphatase PTPRQ 0.0021 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0071 0.0102 0.0154
Loa Loa (eye worm) hypothetical protein 0.0211 0.0365 0.0573
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.029 0.0513 0.1573
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0026 0.0018 0.0054
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0018 0.0019
Schistosoma mansoni cercarial elastase (S01 family) 0.02 0.0345 0.1059
Schistosoma mansoni alpha-1 adrenergic receptor 0.0026 0.0018 0.0054
Mycobacterium leprae probable zinc metalloprotease 0.0285 0.0504 0.1118
Plasmodium vivax vivapain-2 0.0022 0.001 0.0023
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0021 0.0008 0.0013
Schistosoma mansoni hypothetical protein 0.0309 0.0549 0.1682
Echinococcus multilocularis usherin 0.0021 0.0008 0.0009
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0285 0.0504 0.1169
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0035 0.0035 0.0215
Onchocerca volvulus 0.0022 0.001 0.0002
Toxoplasma gondii peptidase family M13 protein 0.0285 0.0504 0.1169
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0826 0.1519 0.1675
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0026 0.0018 0.002
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.02 0.0345 0.1059
Brugia malayi Cadherin domain containing protein 0.0326 0.0582 0.0928
Echinococcus multilocularis neurogenic locus protein delta 0.0326 0.0582 0.0642
Echinococcus granulosus 7tm_1 domain containing protein 0.0026 0.0018 0.0019
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0021 0.0008 0.0004
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0005 0.0006
Entamoeba histolytica hypothetical protein 0.0036 0.0037 1
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0007 0.0015
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0005 0.0009
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0021 0.0008 0.0004
Echinococcus granulosus tm gpcr rhodopsin 0.0026 0.0018 0.0019
Echinococcus multilocularis tachykinin peptides receptor 99D 0.074 0.1358 0.1498
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0057 0.0075 0.0118
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.002 0.0032
Brugia malayi hypothetical protein 0.0026 0.0018 0.0028
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0026 0.0018 0.0019
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0173 0.0401
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Echinococcus granulosus glycoprotein Antigen 5 0.02 0.0345 0.0381
Plasmodium vivax vivapain-2 0.0022 0.001 0.0023
Onchocerca volvulus 0.0026 0.0018 0.0009
Onchocerca volvulus Matrilysin homolog 0.1275 0.2362 0.2356
Brugia malayi EGF-like domain containing protein 0.0326 0.0582 0.0928
Echinococcus granulosus sex peptide receptor 0.0026 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0338 0.0604 0.0956
Brugia malayi Dopamine receptor protein 1 0.0026 0.0018 0.0028
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0059 0.0359
Schistosoma mansoni hypothetical protein 0.0074 0.0109 0.0333
Echinococcus multilocularis neuropeptides capa receptor 0.0026 0.0018 0.0019
Echinococcus multilocularis anosmin 1 0.0021 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.001 0.0235
Echinococcus granulosus neuropeptide receptor A26 0.0026 0.0018 0.0019
Echinococcus granulosus neuropeptide receptor 0.0026 0.0018 0.0019
Schistosoma mansoni hypothetical protein 0.0326 0.0582 0.1784
Brugia malayi hypothetical protein 0.0026 0.0018 0.0028
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Brugia malayi Fibronectin type III domain containing protein 0.0021 0.0008 0.0013
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0144 0.0239 0.0733
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.001 0.0235
Echinococcus granulosus cpg binding protein 0.0035 0.0035 0.0039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.001 0.0235
Echinococcus multilocularis g protein coupled receptor 0.0026 0.0018 0.0019
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0016
Schistosoma mansoni hypothetical protein 0.0074 0.0109 0.0333
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0086 0.0131 0.0248
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.001 0.006
Brugia malayi intermediate filament protein 0.0027 0.002 0.0032
Brugia malayi Matrixin family protein 0.1275 0.2362 0.3768
Echinococcus multilocularis g protein coupled receptor 0.0026 0.0018 0.0019
Brugia malayi Reprolysin 0.0029 0.0023 0.0037
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0026 0.0018 0.0019
Echinococcus granulosus transmembrane protease serine 3 0.02 0.0345 0.0381
Brugia malayi Cathepsin L-like precursor 0.0022 0.001 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0027 0.0082
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.001 0.006
Loa Loa (eye worm) neuropeptide F receptor 0.0026 0.0018 0.002
Schistosoma mansoni hypothetical protein 0.0021 0.0008 0.0025
Schistosoma mansoni histamine h1 receptor 0.0026 0.0018 0.0054
Schistosoma mansoni biogenic amine receptor 0.0026 0.0018 0.0054
Echinococcus granulosus cathepsin L cysteine proteinase 0.0022 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Echinococcus granulosus delta-like protein 1 0.0326 0.0582 0.0642
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0026 0.0018 0.0054
Echinococcus multilocularis Netrin receptor DCC 0.0021 0.0008 0.0009
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.002 0.0024
Echinococcus granulosus tm gpcr rhodopsin 0.0026 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Brugia malayi Peptidase family M1 containing protein 0.0119 0.0193 0.0308
Echinococcus multilocularis neuroglian 0.0021 0.0008 0.0009
Echinococcus multilocularis Phosphotidylinositol phosphatase PTPRQ 0.0021 0.0008 0.0009
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0021 0.0008 0.0009
Brugia malayi myotactin form A 0.0021 0.0008 0.0013
Brugia malayi putative neuropeptide receptor 0.0026 0.0018 0.0028
Echinococcus multilocularis somatostatin receptor 0.0026 0.0018 0.0019
Brugia malayi AKH receptor 0.0026 0.0018 0.0028
Echinococcus multilocularis enteropeptidase 0.02 0.0345 0.0381
Trypanosoma cruzi cysteine peptidase, putative 0.0022 0.001 0.006
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0021 0.0008 0.0009
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0005 0.0006
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0059 0.0064
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0035 0.0035 0.0215
Onchocerca volvulus 0.02 0.0345 0.0337
Loa Loa (eye worm) hypothetical protein 0.005 0.0063 0.0093
Onchocerca volvulus 0.0026 0.0018 0.0009
Brugia malayi hypothetical protein 0.0026 0.0018 0.0028
Echinococcus multilocularis neurogenic locus notch protein 0.0326 0.0582 0.0642
Echinococcus granulosus leucine aminopeptidase protein 0.0106 0.0169 0.0186
Schistosoma mansoni DNA helicase recq1 0.002 0.0007 0.002
Loa Loa (eye worm) reprolysin 0.016 0.027 0.0422
Plasmodium falciparum M17 leucyl aminopeptidase 0.0106 0.0169 0.039
Loa Loa (eye worm) hypothetical protein 0.0071 0.0102 0.0154
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.02 0.0345 0.1059
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Echinococcus granulosus G1Y162 protein 0.0021 0.0008 0.0009
Brugia malayi Fibronectin type III domain containing protein 0.0021 0.0008 0.0013
Onchocerca volvulus 0.0033 0.0032 0.0024
Onchocerca volvulus 0.0239 0.0418 0.041
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.0018 0.0054
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.0173 0.0345
Echinococcus granulosus Fibronectin type III domain containing protein 0.0021 0.0008 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0005 0.0016
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0035 0.0035 0.0039
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.0622 0.1136 0.1812
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0731 0.1341 0.4112
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Mycobacterium tuberculosis Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) 0.2314 0.4311 1
Brugia malayi GCC2 and GCC3 family protein 0.0326 0.0582 0.0928
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0026 0.0018 0.0054
Loa Loa (eye worm) hypothetical protein 0.1275 0.2362 0.3762
Echinococcus granulosus muscleblind protein 0.0338 0.0604 0.0666
Echinococcus granulosus neuropeptide receptor 0.0026 0.0018 0.0019
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0026 0.0018 0.0019
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0018 0.0019
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0021 0.0008 0.0009
Brugia malayi putative neuropeptide receptor NPR1 0.0026 0.0018 0.0028
Echinococcus granulosus titin 0.0021 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0007 0.0015
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0035 0.0035 0.0039
Echinococcus granulosus notch 0.0326 0.0582 0.0642
Echinococcus granulosus roundabout 2 0.0021 0.0008 0.0009
Schistosoma mansoni hypothetical protein 0.0026 0.0018 0.0054
Echinococcus multilocularis aminopeptidase N 0.0119 0.0193 0.0213
Schistosoma mansoni neprilysin 0.0074 0.0109 0.0333
Plasmodium vivax glutathione reductase, putative 0.0048 0.0059 0.0135
Echinococcus multilocularis cell adhesion molecule 0.0021 0.0008 0.0009
Schistosoma mansoni opsin-like receptor 0.0026 0.0018 0.0054
Loa Loa (eye worm) UNCoordinated family member 0.0021 0.0008 0.0004
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0021 0.0009 0.0014
Schistosoma mansoni hypothetical protein 0.0074 0.0109 0.0333
Loa Loa (eye worm) hypothetical protein 0.0211 0.0365 0.0573
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0017 0.0039
Mycobacterium leprae PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) 0.2314 0.4311 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0018 0.0019
Brugia malayi PXA domain containing protein 0.0019 0.0005 0.0009
Echinococcus granulosus fibronectin type III domain-containing protein 0.0021 0.0008 0.0009
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0144 0.0239 0.0733
Loa Loa (eye worm) hypothetical protein 0.0216 0.0374 0.0588
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0005 0.0006
Toxoplasma gondii thioredoxin reductase 0.0048 0.0059 0.0135
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.001 0.0235
Loa Loa (eye worm) hypothetical protein 0.0216 0.0374 0.0588
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0026 0.0018 0.0019
Mycobacterium ulcerans peptide deformylase 0.2314 0.4311 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.001 0.006
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0035 0.0035 0.0837
Echinococcus multilocularis neuropeptide Y receptor 0.0026 0.0018 0.0019
Loa Loa (eye worm) angiogenesis inhibito 0.0033 0.0031 0.0041
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.1491 0.2766 0.4408
Loa Loa (eye worm) hypothetical protein 0.02 0.0345 0.0543
Onchocerca volvulus 0.0026 0.0018 0.0009
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.02 0.0345 0.1059
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0021 0.0008 0.0009
Echinococcus granulosus hypothetical protein 0.0026 0.0018 0.0019
Echinococcus granulosus expressed protein 0.0376 0.0674 0.0743
Brugia malayi CXXC zinc finger family protein 0.0033 0.0032 0.0051
Loa Loa (eye worm) hypothetical protein 0.0216 0.0374 0.0588
Echinococcus multilocularis sex peptide receptor 0.0026 0.0018 0.0019
Schistosoma mansoni biogenic amine (5HT) receptor 0.0026 0.0018 0.0054
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0064 0.007
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Plasmodium vivax peptide deformylase, putative 0.2314 0.4311 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0026 0.0018 0.0028
Echinococcus multilocularis allatostatin A receptor 0.0026 0.0018 0.0019
Onchocerca volvulus Cathepsin F homolog 0.0022 0.001 0.0002
Mycobacterium tuberculosis Probable reductase 0.0109 0.0173 0.0401
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.001 0.0235
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0035 0.0035 0.0039
Onchocerca volvulus Matrix metalloproteinase homolog 0.2766 0.5159 0.5155
Loa Loa (eye worm) hypothetical protein 0.02 0.0345 0.0543
Brugia malayi Papain family cysteine protease containing protein 0.0022 0.001 0.0016
Loa Loa (eye worm) neuropeptide F receptor 0.0026 0.0018 0.002
Schistosoma mansoni leucine aminopeptidase 0.0021 0.0009 0.0027
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0026 0.0018 0.0054
Brugia malayi EGF-like domain containing protein 0.0326 0.0582 0.0928
Echinococcus multilocularis musashi 0.0027 0.002 0.0022
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0026 0.0018 0.0054
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0086 0.0131 0.0304
Brugia malayi hypothetical protein 0.0019 0.0005 0.0009
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.0173 0.0401
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0035 0.0035 0.0039
Onchocerca volvulus Matrilysin homolog 0.3245 0.6058 0.6055
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0086 0.0131 0.0304
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0009 0.0014
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.016 0.027 0.0826
Schistosoma mansoni growth hormone secretagogue receptor 0.0026 0.0018 0.0054
Leishmania major cathepsin L-like protease 0.0022 0.001 0.006
Brugia malayi EGF-like domain containing protein 0.0326 0.0582 0.0928
Brugia malayi myotactin form B 0.0021 0.0008 0.0013
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0106 0.0169 0.1035
Loa Loa (eye worm) matrix metalloproteinase 0.1275 0.2362 0.3762
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0026 0.0018 0.0019
Loa Loa (eye worm) G-protein coupled receptor 0.0026 0.0018 0.002
Onchocerca volvulus 0.0022 0.001 0.0002
Echinococcus granulosus intermediate filament protein 0.0027 0.002 0.0022
Chlamydia trachomatis cytosol aminopeptidase 0.0106 0.0169 0.039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.001 0.006
Schistosoma mansoni neuropeptide f receptor 76f 0.0026 0.0018 0.0054
Brugia malayi G-protein coupled receptor 0.0026 0.0018 0.0028
Plasmodium falciparum peptide deformylase 0.2314 0.4311 1
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0021 0.0008 0.0025
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0032 0.0042
Brugia malayi Pre-SET motif family protein 0.0031 0.0027 0.0043
Schistosoma mansoni hypothetical protein 0.0326 0.0582 0.1784
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0005 0.0016
Brugia malayi Hemopexin family protein 0.1603 0.2977 0.4749
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0026 0.0018 0.0054
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0018 0.0054
Loa Loa (eye worm) myotactin form A 0.0021 0.0008 0.0004
Echinococcus granulosus somatostatin receptor 0.0026 0.0018 0.0019
Onchocerca volvulus Neuropeptide F receptor homolog 0.0026 0.0018 0.0009
Schistosoma mansoni peptidase Clp (S14 family) 0.0086 0.0131 0.0402
Schistosoma mansoni hypothetical protein 0.0475 0.0861 0.2639
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0816 0.15 0.1655
Echinococcus multilocularis microtubule associated protein 2 0.1563 0.2903 0.3202
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0023 0.0028
Echinococcus multilocularis serotonin receptor 0.0026 0.0018 0.0019
Onchocerca volvulus 0.02 0.0345 0.0337
Brugia malayi EGF-like domain containing protein 0.0326 0.0582 0.0928
Brugia malayi EGF-like domain containing protein 0.0326 0.0582 0.0928
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.003 0.0025 0.0058
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.0883 0.1626 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.001 0.0235
Brugia malayi Probable ClpP-like protease 0.0086 0.0131 0.0209
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0026 0.0018 0.0019
Schistosoma mansoni hypothetical protein 0.0034 0.0034 0.0102
Brugia malayi protein unc-22 0.0021 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0216 0.0374 0.0588
Echinococcus multilocularis endothelin converting enzyme 1 0.0285 0.0504 0.0556
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0005 0.0006
Schistosoma mansoni cell adhesion molecule 0.0021 0.0008 0.0025
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.02 0.0345 0.0381
Schistosoma mansoni titin 0.0021 0.0008 0.0025
Onchocerca volvulus 0.0242 0.0424 0.0416
Mycobacterium ulcerans zinc metalloprotease 0.0285 0.0504 0.1169
Schistosoma mansoni neuropeptide receptor 0.0026 0.0018 0.0054
Entamoeba histolytica hypothetical protein 0.0036 0.0037 1
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0005 0.0006
Onchocerca volvulus 0.0022 0.001 0.0002
Schistosoma mansoni neuropeptide receptor 0.0026 0.0018 0.0054
Loa Loa (eye worm) intermediate filament protein 0.0027 0.002 0.0024
Brugia malayi neuropeptide F receptor 0.0026 0.0018 0.0028
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0016
Toxoplasma gondii calcium binding egf domain-containing protein 0.0071 0.0102 0.0236
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0007 0.0015
Plasmodium falciparum thioredoxin reductase 0.0048 0.0059 0.0135
Brugia malayi Trypsin family protein 0.02 0.0345 0.0551
Echinococcus granulosus dnaJ subfamily B 0.0475 0.0861 0.0949
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0005 0.0016
Echinococcus granulosus g protein coupled receptor 0.0026 0.0018 0.0019
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0021 0.0008 0.0004
Echinococcus multilocularis Fibronectin, type III 0.0021 0.0008 0.0009
Echinococcus multilocularis fmrfamide receptor 0.0026 0.0018 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0018 0.0019
Onchocerca volvulus 0.0026 0.0018 0.0009
Schistosoma mansoni hypothetical protein 0.0171 0.0289 0.0886
Loa Loa (eye worm) hypothetical protein 0.02 0.0345 0.0543
Echinococcus granulosus peptide allatostatin:somatostatin 0.0026 0.0018 0.0019
Loa Loa (eye worm) notch protein 0.0326 0.0582 0.092
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Brugia malayi cytosol aminopeptidase 0.0021 0.0009 0.0014
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0021 0.0008 0.0025
Leishmania major cathepsin L-like protease 0.0022 0.001 0.006
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0005 0.0006
Schistosoma mansoni cpg binding protein 0.0035 0.0035 0.0108
Entamoeba histolytica cysteine proteinase, putative 0.0022 0.001 0.1435
Schistosoma mansoni factor for adipocyte differentiation 0.0021 0.0008 0.0025
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0008 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.001 0.0235
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.02 0.0345 0.0381
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0027 0.0062
Schistosoma mansoni hypothetical protein 0.0171 0.0289 0.0886
Echinococcus multilocularis fat cadherin tumor suppressor 0.0326 0.0582 0.0642
Schistosoma mansoni protein tyrosine phosphatase 0.0021 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0005 0.0009
Loa Loa (eye worm) TYRA-2 protein 0.0026 0.0018 0.002
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0106 0.0169 0.0335
Schistosoma mansoni opsin-like receptor 0.0026 0.0018 0.0054
Onchocerca volvulus 0.0026 0.0018 0.0009
Schistosoma mansoni cercarial elastase (S01 family) 0.02 0.0345 0.1059
Schistosoma mansoni hypothetical protein 0.0127 0.0207 0.0634
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.001 0.0235
Brugia malayi Disintegrin family protein 0.0131 0.0216 0.0344
Echinococcus multilocularis orexin receptor type 2 0.0026 0.0018 0.0019
Echinococcus multilocularis lamin dm0 0.0027 0.002 0.0022
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0008 0.0013
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0018 0.0019
Brugia malayi Kringle domain containing protein 0.0309 0.0549 0.0875
Brugia malayi EGF-like domain containing protein 0.0326 0.0582 0.0928
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.001 0.0235
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Echinococcus multilocularis g-protein coupled receptor 0.0026 0.0018 0.0019
Schistosoma mansoni neuropeptide receptor 0.0026 0.0018 0.0054
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0106 0.0169 0.1035
Schistosoma mansoni tripartite motif protein trim9 0.0021 0.0008 0.0025
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.016 0.027 0.0826
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0022 0.001 0.0011
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.02 0.0345 0.0551
Brugia malayi Cathepsin L-like precursor 0.0022 0.001 0.0016
Loa Loa (eye worm) projectin 0.0021 0.0008 0.0004
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0005 0.0126
Leishmania major cathepsin L-like protease 0.0022 0.001 0.006
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0021 0.0009 0.0054
Schistosoma mansoni hypothetical protein 0.0326 0.0582 0.1784
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Schistosoma mansoni cathepsin F (C01 family) 0.0022 0.001 0.003
Brugia malayi SPRY domain containing protein 0.0021 0.0008 0.0013
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0024 0.0026
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Trypanosoma brucei Peptide deformylase 2 0.0883 0.1626 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0018 0.0054
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0005 0.0006
Echinococcus multilocularis muscleblind protein 0.0338 0.0604 0.0666
Schistosoma mansoni amine GPCR 0.0026 0.0018 0.0054
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0071 0.0102 0.0154
Schistosoma mansoni hypothetical protein 0.0074 0.0109 0.0333
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0021 0.0009 0.0027
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0021 0.0008 0.0009
Echinococcus multilocularis protein jagged 1 0.0326 0.0582 0.0642
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0064 0.0196
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0007 0.0155
Leishmania major hypothetical protein, conserved 0.0309 0.0549 0.3373
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0007 0.0155
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0018 0.0019
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.0196 0.0398
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0005 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0018 0.0019
Plasmodium falciparum cysteine proteinase falcipain 3 0.0022 0.001 0.0023
Leishmania major hypothetical protein, conserved 0.0021 0.0008 0.0049
Trypanosoma brucei Aminopeptidase M1, putative 0.0035 0.0035 0.0215
Schistosoma mansoni amine GPCR 0.0026 0.0018 0.0054
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0027 0.003
Trypanosoma cruzi cruzipain precursor, putative 0.0022 0.001 0.006
Onchocerca volvulus 0.0326 0.0582 0.0574
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0021 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Mycobacterium ulcerans hypothetical protein 0.02 0.0345 0.0801
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0007 0.004
Loa Loa (eye worm) fibroinase 0.0022 0.001 0.0007
Trypanosoma brucei Polypeptide deformylase 1 0.0883 0.1626 1
Schistosoma mansoni slit 0.0326 0.0582 0.1784
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0021 0.0008 0.0009
Brugia malayi Thioredoxin reductase 0.0048 0.0059 0.0093
Wolbachia endosymbiont of Brugia malayi peptide deformylase 0.2314 0.4311 1
Echinococcus multilocularis geminin 0.0171 0.0289 0.0319
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0026 0.0018 0.0009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0018 0.0019
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0021 0.0008 0.0009
Brugia malayi Peptidase family M13 containing protein 0.0285 0.0504 0.0804
Echinococcus multilocularis fibronectin type III domain-containing protein 0.0021 0.0008 0.0009
Echinococcus granulosus Netrin receptor DCC 0.0021 0.0008 0.0009
Giardia lamblia High cysteine protein 0.0326 0.0582 1
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0021 0.0009 0.0054
Brugia malayi G protein-coupled receptor F59B2.13 0.0026 0.0018 0.0028
Brugia malayi Cadherin domain containing protein 0.0326 0.0582 0.0928
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Echinococcus multilocularis titin 0.0021 0.0008 0.0009
Brugia malayi hypothetical protein 0.0035 0.0035 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.001 0.0235
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.0007
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0127 0.0207 0.0228
Brugia malayi sulfakinin receptor protein 0.0026 0.0018 0.0028
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0018 0.0019
Brugia malayi Matrixin family protein 0.1275 0.2362 0.3768
Onchocerca volvulus 0.0141 0.0234 0.0226
Schistosoma mansoni cpg binding protein 0.0035 0.0035 0.0108
Echinococcus multilocularis muscleblind protein 1 0.0338 0.0604 0.0666
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0018 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0005 0.0016
Echinococcus multilocularis neuropeptides capa receptor 0.0026 0.0018 0.0019
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0026 0.0018 0.0028
Echinococcus multilocularis anosmin 1 0.0021 0.0008 0.0009
Onchocerca volvulus Putative cubilin 0.0326 0.0582 0.0574
Loa Loa (eye worm) hypothetical protein 0.0338 0.0604 0.0956
Schistosoma mansoni hypothetical protein 0.0074 0.0109 0.0333
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0022 0.001 0.0235
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0021 0.0008 0.0009
Echinococcus granulosus tissue type plasminogen activator 0.0309 0.0549 0.0605
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0086 0.0131 0.0145
Treponema pallidum polypeptide deformylase (def) 0.2314 0.4311 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0027 0.0082
Trypanosoma cruzi Fibronectin type III domain containing protein, putative 0.0021 0.0008 0.0049
Brugia malayi angiogenesis inhibito 0.0163 0.0275 0.0438
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0018 0.0054
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.02 0.0345 0.1059
Brugia malayi larval opioid receptor 0.0026 0.0018 0.0028
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0326 0.0582 0.0928
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.001 0.006
Echinococcus multilocularis peptidase Clp (S14 family) 0.0057 0.0075 0.0083
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0086 0.0131 0.0304
Schistosoma mansoni hypothetical protein 0.0021 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Echinococcus multilocularis neuropeptide Y receptor 0.0026 0.0018 0.0019
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0026 0.0018 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.001 0.0235
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Echinococcus multilocularis titin 0.0021 0.0008 0.0009
Echinococcus granulosus adam 0.029 0.0513 0.0566
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.001 0.0235
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0005 0.0006
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0008 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0309 0.0549 0.3373
Schistosoma mansoni cathepsin F (C01 family) 0.0022 0.001 0.003
Echinococcus granulosus lamin 0.0027 0.002 0.0022
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0026 0.0018 0.0019
Onchocerca volvulus Papilin homolog 0.0067 0.0095 0.0087
Echinococcus granulosus neural cadherin 0.0326 0.0582 0.0642
Echinococcus granulosus neurogenic locus notch protein 0.0326 0.0582 0.0642
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0126
Echinococcus granulosus protein jagged 2 0.0326 0.0582 0.0642
Brugia malayi Peptidase family M1 containing protein 0.0035 0.0035 0.0056
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0057 0.0075 0.0175
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0021 0.0008 0.0025
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0008 0.0013
Echinococcus granulosus disintegrin and metalloproteinase 0.0131 0.0216 0.0237
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.001 0.006
Loa Loa (eye worm) hypothetical protein 0.1754 0.3261 0.5198
Loa Loa (eye worm) RecQ helicase 0.002 0.0007 0.0002
Trypanosoma cruzi Fibronectin type III domain containing protein, putative 0.0021 0.0008 0.0049
Onchocerca volvulus 0.0022 0.001 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0018 0.0019
Loa Loa (eye worm) peptidase family M13 containing protein 0.0211 0.0365 0.0573
Schistosoma mansoni factor for adipocyte differentiation 0.0021 0.0008 0.0025
Schistosoma mansoni egf-like domain protein 0.0071 0.0102 0.0312
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0005 0.0009
Schistosoma mansoni hypothetical protein 0.0036 0.0037 0.0113
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0069 0.01 0.0305
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0017 0.0102
Echinococcus multilocularis leucyl aminopeptidase 0.0021 0.0009 0.001
Echinococcus granulosus serotonin receptor 0.0026 0.0018 0.0019
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0086 0.0131 0.0304
Brugia malayi Serotonin receptor 0.0026 0.0018 0.0028
Toxoplasma gondii EGF family domain-containing protein 0.0326 0.0582 0.1349
Loa Loa (eye worm) hypothetical protein 0.0107 0.017 0.0263
Brugia malayi Muscleblind-like protein 0.0338 0.0604 0.0964
Loa Loa (eye worm) glutathione reductase 0.0048 0.0059 0.0085
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.4848 0.9066 1
Schistosoma mansoni amine GPCR 0.0026 0.0018 0.0054
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0018
Echinococcus granulosus neuroglian 0.0021 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0216 0.0374 0.0588
Echinococcus granulosus enteropeptidase 0.02 0.0345 0.0381
Brugia malayi Pre-SET motif family protein 0.021 0.0364 0.058
Echinococcus granulosus anosmin 1 0.0021 0.0008 0.0009
Echinococcus granulosus adam 17 protease 0.1448 0.2685 0.2962
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.071 0.1302 0.3993
Schistosoma mansoni cercarial elastase (S01 family) 0.02 0.0345 0.1059
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0021 0.0008 0.0009
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0037 0.0041
Brugia malayi hypothetical protein 0.0026 0.0018 0.0028
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0086 0.0131 0.0304
Schistosoma mansoni cercarial elastase (S01 family) 0.02 0.0345 0.1059
Schistosoma mansoni nephrin 0.0021 0.0008 0.0025
Entamoeba histolytica hypothetical protein 0.0036 0.0037 1
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0005 0.0016
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0017 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0008 0.0025
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0035 0.0035 0.0107
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0035 0.0035 0.0215
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0026 0.0018 0.002
Echinococcus multilocularis neuropeptide FF receptor 2 0.0026 0.0018 0.0019
Schistosoma mansoni ephrin receptor 0.0021 0.0008 0.0025
Echinococcus granulosus Phosphotidylinositol phosphatase PTPRQ 0.0021 0.0008 0.0009
Echinococcus granulosus peptidase Clp S14 family 0.0057 0.0075 0.0083
Schistosoma mansoni hypothetical protein 0.0326 0.0582 0.1784
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0005 0.0016
Schistosoma mansoni hypothetical protein 0.02 0.0345 0.1059
Brugia malayi hypothetical protein 0.029 0.0513 0.0818
Loa Loa (eye worm) hypothetical protein 0.0159 0.0267 0.0417
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0026 0.0018 0.0028
Loa Loa (eye worm) hypothetical protein 0.0285 0.0504 0.0796
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0059 0.0135
Echinococcus multilocularis cpg binding protein 0.0035 0.0035 0.0039
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0005 0.0006
Echinococcus granulosus neurogenic locus notch protein 4 0.0326 0.0582 0.0642
Brugia malayi hypothetical protein 0.0025 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.1491 0.2766 0.4413
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0021 0.0008 0.0009
Echinococcus multilocularis dnaJ subfamily B 0.0475 0.0861 0.0949
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0008 0.0013
Leishmania major cathepsin L-like protease 0.0022 0.001 0.006
Echinococcus multilocularis leucine aminopeptidase protein 0.0106 0.0169 0.0186
Brugia malayi Muscle positioning protein 4 0.0326 0.0582 0.0928
Schistosoma mansoni cercarial elastase (S01 family) 0.02 0.0345 0.1059
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Echinococcus granulosus anosmin 1 0.0021 0.0008 0.0009
Echinococcus multilocularis anosmin 1 0.0021 0.0008 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0126
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0069 0.01 0.0305
Schistosoma mansoni intermediate filament proteins 0.0027 0.002 0.0061
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.0018 0.0054
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0021 0.0009 0.0054
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0016
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0071 0.0102 0.0163
Brugia malayi Serotonin receptor 0.0026 0.0018 0.0028
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0071 0.0102 0.0154
Echinococcus multilocularis fibropellin Ia 0.0326 0.0582 0.0642
Echinococcus granulosus Mastin 0.02 0.0345 0.0381
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0057 0.0075 0.0175
Echinococcus granulosus protein jagged 1 0.0326 0.0582 0.0642
Loa Loa (eye worm) hypothetical protein 0.0084 0.0127 0.0194
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0074 0.0109 0.0333
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Schistosoma mansoni neuropeptide F-like receptor 0.0026 0.0018 0.0054
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.1491 0.2766 0.6416
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.001 0.006
Echinococcus multilocularis roundabout 2 0.0021 0.0008 0.0009
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0005 0.0006
Leishmania major cathepsin L-like protease 0.0022 0.001 0.006
Schistosoma mansoni neuroglian 0.0021 0.0008 0.0025
Echinococcus multilocularis Tolloid protein 1 0.0071 0.0102 0.0112
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0173 0.0401
Onchocerca volvulus 0.0027 0.002 0.0012
Echinococcus multilocularis adam 0.029 0.0513 0.0566
Trypanosoma brucei aminopeptidase, putative 0.0021 0.0009 0.0054
Brugia malayi hypothetical protein 0.0021 0.0008 0.0013
Echinococcus multilocularis cathepsin L cysteine protease 0.0022 0.001 0.0011
Echinococcus granulosus cell adhesion molecule 0.0021 0.0008 0.0009
Brugia malayi Delta serrate ligand family protein 0.0326 0.0582 0.0928
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.001 0.0235
Onchocerca volvulus Cathepsin L homolog 0.0022 0.001 0.0002
Echinococcus multilocularis fmrfamide receptor 0.0026 0.0018 0.0019
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0064 0.0196
Echinococcus multilocularis G protein coupled receptor 139 0.0026 0.0018 0.0019
Schistosoma mansoni notch 0.0326 0.0582 0.1784
Echinococcus multilocularis neuropeptide receptor 0.0026 0.0018 0.0019
Brugia malayi Tachykinin-like peptides receptor 99D 0.0026 0.0018 0.0028
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.071 0.1302 0.1436
Echinococcus multilocularis adam 17 protease 0.1316 0.2439 0.269
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0022
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0008 0.0013
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0021 0.0009 0.001
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.02 0.0345 0.0381
Brugia malayi glutathione reductase 0.0048 0.0059 0.0093
Brugia malayi G protein-coupled receptor 0.0026 0.0018 0.0028
Loa Loa (eye worm) cysteine protease 0.0022 0.001 0.0007
Echinococcus granulosus tm gpcr rhodopsin 0.0026 0.0018 0.0019
Echinococcus granulosus neuropeptide s receptor 0.0026 0.0018 0.0019
Schistosoma mansoni dihydroceramide desaturase 0.0131 0.0216 0.066
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0106 0.0169 0.1035
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0059 0.0085
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0023 0.0012 0.0072
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0086 0.0131 0.0304
Echinococcus multilocularis disintegrin and metalloproteinase 0.0131 0.0216 0.0237
Trypanosoma cruzi Peptide deformylase 2, putative 0.0883 0.1626 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0021 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0026 0.0018 0.0019
Echinococcus multilocularis glycoprotein Antigen 5 0.02 0.0345 0.0381
Echinococcus multilocularis cysteine protease 0.0022 0.001 0.0011
Chlamydia trachomatis peptide deformylase 0.2314 0.4311 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0021 0.0008 0.0004
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0017 0.0039
Brugia malayi Matrixin family protein 0.1275 0.2362 0.3768
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0106 0.0169 0.1035
Schistosoma mansoni cercarial elastase (S01 family) 0.02 0.0345 0.1059
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0026 0.0018 0.0054
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0035 0.0035 0.0039
Echinococcus granulosus 7TM GPCR rhodopsin 0.0026 0.0018 0.0019
Echinococcus granulosus laminin 0.0071 0.0102 0.0112
Brugia malayi hypothetical protein 0.0026 0.0018 0.0028
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0086 0.0131 0.0145
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0035 0.0035 0.0837
Loa Loa (eye worm) hypothetical protein 0.02 0.0345 0.0543
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Onchocerca volvulus 0.0022 0.001 0.0002
Echinococcus multilocularis tissue type plasminogen activator 0.0309 0.0549 0.0605
Onchocerca volvulus 0.0026 0.0018 0.0009
Loa Loa (eye worm) hypothetical protein 0.1275 0.2362 0.3762
Brugia malayi hypothetical protein 0.0036 0.0037 0.0059
Brugia malayi Trypsin family protein 0.02 0.0345 0.0551
Loa Loa (eye worm) hypothetical protein 0.0031 0.0027 0.0034
Loa Loa (eye worm) TK/ROR protein kinase 0.0309 0.0549 0.0867
Echinococcus multilocularis roundabout 2 0.0021 0.0008 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.001 0.006
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0127 0.0207 0.0228
Brugia malayi ADAM-TS Spacer 1 family protein 0.031 0.0551 0.0879
Echinococcus granulosus roundabout 2 0.0021 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0285 0.0504 0.0796
Echinococcus granulosus Fibronectin type III 0.0021 0.0008 0.0009
Echinococcus multilocularis neuropeptide receptor 0.0026 0.0018 0.0019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.001 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.001 0.0235
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0008 0.0013
Schistosoma mansoni cell adhesion molecule 0.0021 0.0008 0.0025
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0021 0.0008 0.0004
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0021 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0211 0.0365 0.0573
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0309 0.0549 0.1272
Trypanosoma cruzi Aminopeptidase M1, putative 0.0035 0.0035 0.0215
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0045
Trypanosoma cruzi cysteine peptidase, putative 0.0022 0.001 0.006
Loa Loa (eye worm) melatonin receptor type 1A 0.0026 0.0018 0.002
Onchocerca volvulus 0.0026 0.0018 0.0009
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0023 0.0012 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0008 0.0049
Schistosoma mansoni thyroid hormone receptor 0.0137 0.0226 0.0693
Schistosoma mansoni lamin 0.0027 0.002 0.0061
Brugia malayi Trypsin family protein 0.02 0.0345 0.0551
Brugia malayi Lethal protein 805 0.0021 0.0008 0.0013
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0021 0.0009 0.0006
Echinococcus granulosus fmrfamide receptor 0.0026 0.0018 0.0019
Brugia malayi ADAMTS-like protease 0.0163 0.0275 0.0438
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0008 0.0013
Brugia malayi GnHR receptor homolog 0.0026 0.0018 0.0028
Echinococcus granulosus G protein coupled receptor 139 0.0026 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.001 0.0235
Echinococcus granulosus leucyl aminopeptidase 0.0021 0.0009 0.001
Echinococcus granulosus roundabout 2 0.0021 0.0008 0.0009
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0086 0.0131 0.0304
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0064 0.007
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0035 0.0035 0.0039
Leishmania major cathepsin L-like protease 0.0022 0.001 0.006
Schistosoma mansoni myosin-binding protein-related 0.0021 0.0008 0.0025
Echinococcus multilocularis leucyl aminopeptidase 0.0021 0.0009 0.001
Onchocerca volvulus 0.0309 0.0549 0.0541
Mycobacterium ulcerans aminopeptidase N PepN 0.0035 0.0035 0.0081
Schistosoma mansoni hypothetical protein 0.0026 0.0018 0.0054
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.4848 0.9066 1
Schistosoma mansoni hypothetical protein 0.02 0.0345 0.1059
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0018 0.0054
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0016
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0064 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.001 0.0235
Trypanosoma cruzi Peptide deformylase 2, putative 0.0883 0.1626 1
Loa Loa (eye worm) peptidase family M13 containing protein 0.0211 0.0365 0.0573
Toxoplasma gondii hypothetical protein 0.003 0.0025 0.0058
Onchocerca volvulus 0.0026 0.0018 0.0009
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0026 0.0018 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.001 0.0235
Brugia malayi hypothetical protein 0.02 0.0345 0.0551
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Brugia malayi EGF-like domain containing protein 0.0326 0.0582 0.0928
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0026 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.016 0.027 0.0422
Schistosoma mansoni titin 0.0021 0.0008 0.0025
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0021 0.0009 0.0054
Trypanosoma cruzi cysteine peptidase, putative 0.0022 0.001 0.006
Onchocerca volvulus 0.0031 0.0027 0.0019
Mycobacterium ulcerans leucyl aminopeptidase 0.0106 0.0169 0.039
Schistosoma mansoni cercarial elastase (S01 family) 0.02 0.0345 0.1059
Loa Loa (eye worm) hypothetical protein 0.0309 0.0549 0.0867
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0026 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Schistosoma mansoni hypothetical protein 0.0026 0.0018 0.0054
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0022 0.001 0.0023
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0069 0.01 0.0305
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0022 0.001 0.0007
Plasmodium falciparum cysteine repeat modular protein 1 0.0309 0.0549 0.1272
Echinococcus granulosus neuropeptide FF receptor 2 0.0026 0.0018 0.0019
Echinococcus granulosus geminin 0.0171 0.0289 0.0319
Schistosoma mansoni hypothetical protein 0.1603 0.2977 0.913
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0005 0.0006
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0026 0.0018 0.0054
Schistosoma mansoni biogenic amine receptor 0.0026 0.0018 0.0054
Onchocerca volvulus 0.0026 0.0018 0.0009
Echinococcus granulosus protein jagged 2 0.0326 0.0582 0.0642
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0007 0.0155
Brugia malayi hypothetical protein 0.0026 0.0018 0.0028
Brugia malayi metalloprotease 0.0029 0.0023 0.0037
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0326 0.0582 0.1784
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0106 0.0169 0.039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0022 0.001 0.0235
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Echinococcus multilocularis laminin 0.0071 0.0102 0.0112
Echinococcus granulosus cathepsin l cysteine peptidase 0.0022 0.001 0.0011
Echinococcus granulosus g protein coupled receptor 0.0026 0.0018 0.0019
Brugia malayi hypothetical protein 0.0026 0.0018 0.0028
Trichomonas vaginalis set domain proteins, putative 0.0239 0.0418 1
Schistosoma mansoni septate junction protein 0.0326 0.0582 0.1784
Schistosoma mansoni neuropeptide receptor 0.0026 0.0018 0.0054
Echinococcus multilocularis dro:myosuppressin receptor 0.0026 0.0018 0.0019
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0035 0.0035 0.0039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.001 0.0235
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.003 0.0025 0.0058
Schistosoma mansoni microtubule-associated protein tau 0.1563 0.2903 0.8902
Onchocerca volvulus 0.0026 0.0018 0.0009
Schistosoma mansoni hypothetical protein 0.0331 0.059 0.1808
Toxoplasma gondii leucyl aminopeptidase LAP 0.0106 0.0169 0.039
Onchocerca volvulus 0.02 0.0345 0.0337
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0005 0.0006
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0007 0.0111
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0106 0.0169 0.039
Echinococcus granulosus alpha 1A adrenergic receptor 0.0026 0.0018 0.0019
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0021 0.0008 0.0004
Loa Loa (eye worm) lethal protein 805 0.0021 0.0008 0.0004
Schistosoma mansoni hypothetical protein 0.0326 0.0582 0.1784
Onchocerca volvulus 0.0326 0.0582 0.0574
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0021 0.0008 0.0009
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0034 0.0054
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0021 0.0008 0.0004
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0021 0.0008 0.0004
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0285 0.0504 0.1546
Brugia malayi hypothetical protein 0.0026 0.0018 0.0028
Brugia malayi Fibulin-1 precursor 0.0071 0.0102 0.0163
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0059 0.0064
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0037 0.0041
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0026 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0086 0.0131 0.0304
Loa Loa (eye worm) zinc metallopeptidase 4 0.0069 0.01 0.015
Schistosoma mansoni biogenic amine receptor 0.0026 0.0018 0.0054
Schistosoma mansoni DNA helicase recq5 0.002 0.0007 0.002
Brugia malayi hypothetical protein 0.0026 0.0018 0.0028
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.016 0.027 0.0297
Loa Loa (eye worm) hypothetical protein 0.031 0.0551 0.0871
Echinococcus granulosus neuropeptides capa receptor 0.0026 0.0018 0.0019
Echinococcus granulosus lamin dm0 0.0027 0.002 0.0022
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.1316 0.2439 0.748
Echinococcus multilocularis notch 0.0326 0.0582 0.0642
Brugia malayi Melatonin receptor type 1A 0.0026 0.0018 0.0028
Echinococcus granulosus g protein coupled receptor 0.0026 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Trypanosoma cruzi cysteine peptidase, putative 0.0022 0.001 0.006
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0021 0.0009 0.0014
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0005 0.0006
Toxoplasma gondii hypothetical protein 0.2314 0.4311 1
Onchocerca volvulus 0.1603 0.2977 0.2971
Schistosoma mansoni cell adhesion molecule 0.0021 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0086 0.0131 0.0201
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0027 0.003
Loa Loa (eye worm) aminopeptidase N 0.0035 0.0035 0.0047
Entamoeba histolytica aminopeptidase, putative 0.0035 0.0035 0.9355
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0035 0.0035 0.0039
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0005 0.0006
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0007 0.0007
Brugia malayi G-protein coupled receptor 0.0026 0.0018 0.0028
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0021 0.0008 0.0013
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0026 0.0018 0.0019
Echinococcus granulosus biogenic amine 5HT receptor 0.0026 0.0018 0.0019
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0026 0.0018 0.0019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.001 0.006
Echinococcus granulosus usherin 0.0021 0.0008 0.0009
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0007 0.0007
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0017 0.0039
Brugia malayi Protein kinase domain containing protein 0.0309 0.0549 0.0875
Schistosoma mansoni endothelin-converting enzyme-related 0.0069 0.01 0.0305
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Brugia malayi Fibronectin type III domain containing protein 0.0021 0.0008 0.0013
Loa Loa (eye worm) G-protein coupled receptor 0.0026 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0008 0.0013
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0021 0.0008 0.0025
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0072 0.0104 0.0319
Loa Loa (eye worm) hypothetical protein 0.0092 0.0141 0.0216
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0027 0.003
Echinococcus multilocularis neurogenic locus notch protein 0.0326 0.0582 0.0642
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0071 0.0102 0.0154
Echinococcus multilocularis fibrillin 1 0.0071 0.0102 0.0112
Echinococcus granulosus leucyl aminopeptidase 0.0021 0.0009 0.001
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.02 0.0345 0.0381
Schistosoma mansoni biogenic amine (5HT) receptor 0.0026 0.0018 0.0054
Mycobacterium ulcerans hydrolase 0.1491 0.2766 0.6416
Leishmania major hypothetical protein, conserved 0.0025 0.0017 0.0102
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Echinococcus granulosus neuropeptide Y receptor 0.0026 0.0018 0.0019
Onchocerca volvulus 0.0027 0.002 0.0012
Onchocerca volvulus 0.0022 0.001 0.0002
Echinococcus multilocularis neurogenic locus notch protein 4 0.0326 0.0582 0.0642
Brugia malayi neuropeptide F receptor 0.0026 0.0018 0.0028
Echinococcus granulosus fibropellin Ia 0.0326 0.0582 0.0642
Echinococcus multilocularis neuropeptide s receptor 0.0026 0.0018 0.0019
Schistosoma mansoni cell adhesion molecule 0.0021 0.0008 0.0025
Leishmania major cathepsin L-like protease 0.0022 0.001 0.006
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0005 0.0009
Schistosoma mansoni adenoreceptor 0.0026 0.0018 0.0054
Loa Loa (eye worm) hypothetical protein 0.2766 0.5159 0.8229
Echinococcus granulosus biogenic amine 5HT receptor 0.0026 0.0018 0.0019
Echinococcus multilocularis G-protein coupled receptor, putative 0.0026 0.0018 0.0019
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0007 0.004
Trypanosoma brucei Fibronectin type III domain containing protein, putative 0.0021 0.0008 0.0049
Schistosoma mansoni neprilysin-2 (M13 family) 0.0144 0.0239 0.0733
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0018 0.0054
Loa Loa (eye worm) Notch2 0.0326 0.0582 0.092
Leishmania major polypeptide deformylase-like protein, putative 0.0883 0.1626 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0063 0.0093
Schistosoma mansoni neuropeptide F-like receptor 0.0026 0.0018 0.0054
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0021 0.0008 0.0025
Leishmania major trypanothione reductase 0.0048 0.0059 0.0359
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.0024
Schistosoma mansoni lamin 0.0027 0.002 0.0061
Loa Loa (eye worm) hypothetical protein 0.0285 0.0504 0.0796
Plasmodium falciparum glutathione reductase 0.0048 0.0059 0.0135
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.1754 0.3261 1
Echinococcus multilocularis expressed protein 0.0376 0.0674 0.0743
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Loa Loa (eye worm) ctsf protein 0.0022 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Onchocerca volvulus 0.0026 0.0018 0.0009
Schistosoma mansoni notch 0.0326 0.0582 0.1784
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0008 0.0013
Trypanosoma cruzi aminopeptidase, putative 0.0035 0.0035 0.0215
Onchocerca volvulus 0.1275 0.2362 0.2356
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0026 0.0018 0.0028
Toxoplasma gondii cathepsin CPL 0.0022 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0063 0.0101
Schistosoma mansoni thyroid hormone receptor 0.0137 0.0226 0.0693
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Loa Loa (eye worm) hypothetical protein 0.0067 0.0095 0.0143
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0035 0.0035 0.0039
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Entamoeba histolytica hypothetical protein 0.0036 0.0037 1
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0007 0.0002
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.02 0.0345 0.1059
Schistosoma mansoni notch 0.0326 0.0582 0.1784
Echinococcus granulosus cathepsin l1 0.0022 0.001 0.0011
Echinococcus granulosus allatostatin A receptor 0.0026 0.0018 0.0019
Onchocerca volvulus 0.02 0.0345 0.0337
Echinococcus granulosus g-protein coupled receptor 0.0026 0.0018 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0018 0.0019
Echinococcus granulosus titin 0.0021 0.0008 0.0009
Entamoeba histolytica recQ family helicase, putative 0.002 0.0007 0.0387
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Loa Loa (eye worm) pax transcription factor protein 2 0.0242 0.0424 0.0668
Schistosoma mansoni myosin xvIII 0.0026 0.0018 0.0054
Echinococcus multilocularis Netrin receptor DCC 0.0021 0.0008 0.0009
Echinococcus multilocularis roundabout 2 0.0021 0.0008 0.0009
Echinococcus multilocularis cathepsin L cysteine protease 0.0022 0.001 0.0011
Schistosoma mansoni notch 0.0326 0.0582 0.1784
Schistosoma mansoni cell polarity protein 0.0326 0.0582 0.1784
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.0064 0.0102
Schistosoma mansoni hypothetical protein 0.0326 0.0582 0.1784
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.001 0.0235
Leishmania major cathepsin L-like protease 0.0022 0.001 0.006
Echinococcus multilocularis g protein coupled receptor 0.0026 0.0018 0.0019
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0027 0.0082
Loa Loa (eye worm) metalloprotease 0.0029 0.0023 0.0028
Echinococcus multilocularis Mastin 0.02 0.0345 0.0381
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0026 0.0018 0.0028
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0059 0.0135
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Brugia malayi Trypsin-like protease protein 5 0.02 0.0345 0.0551
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0035 0.0035 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0126
Echinococcus multilocularis protein jagged 2 0.0326 0.0582 0.0642
Brugia malayi Matrixin family protein 0.3357 0.6269 1
Onchocerca volvulus Slit protein homolog 0.0326 0.0582 0.0574
Schistosoma mansoni cercarial elastase (S01 family) 0.02 0.0345 0.1059
Echinococcus granulosus tachykinin peptides receptor 99D 0.074 0.1358 0.1498
Echinococcus granulosus Tolloid protein 1 0.0071 0.0102 0.0112
Loa Loa (eye worm) matrixin family protein 0.3357 0.6269 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0026 0.0018 0.0054
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0069 0.01 0.0305
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0026 0.0018 0.0019
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0026 0.0018 0.0019
Onchocerca volvulus 0.0026 0.0018 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0018 0.0054
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Onchocerca volvulus 0.0026 0.0018 0.0009
Brugia malayi Fibronectin type III domain containing protein 0.0021 0.0008 0.0013
Schistosoma mansoni amine GPCR 0.0026 0.0018 0.0054
Brugia malayi Pax transcription factor protein 2 0.0242 0.0424 0.0676
Echinococcus granulosus bloom syndrome protein 0.002 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Echinococcus granulosus orexin receptor type 2 0.0026 0.0018 0.0019
Echinococcus multilocularis serotonin receptor 0.0026 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0126
Echinococcus multilocularis transmembrane protease serine 3 0.02 0.0345 0.0381
Onchocerca volvulus 0.0035 0.0035 0.0027
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0026 0.0018 0.0019
Loa Loa (eye worm) trypsin family protein 0.02 0.0345 0.0543
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0021 0.0009 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.001 0.0235
Leishmania major cysteine peptidase A (CPA) 0.0022 0.001 0.006
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0005 0.0009
Onchocerca volvulus 0.0326 0.0582 0.0574
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0021 0.0008 0.0013
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.009 0.0208
Echinococcus granulosus contactin 0.0021 0.0008 0.0009
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.0196 0.0453
Schistosoma mansoni cercarial elastase (S01 family) 0.02 0.0345 0.1059
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0007 0.0015
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0007 0.0007
Brugia malayi ORL1-like opioid receptor 0.0026 0.0018 0.0028
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Echinococcus multilocularis neural cadherin 0.0326 0.0582 0.0642
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0017 0.0102
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0326 0.0582 0.0574
Echinococcus multilocularis cysteine protease 0.0022 0.001 0.0011
Brugia malayi peptidase family M13 containing protein 0.0069 0.01 0.0159
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0035 0.0035 0.0215
Onchocerca volvulus Arrow homolog 0.0071 0.0102 0.0094
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0026 0.0018 0.002
Brugia malayi Cathepsin L-like precursor 0.0022 0.001 0.0016
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0005 0.0016
Brugia malayi Protein-tyrosine phosphatase 0.0021 0.0008 0.0013
Schistosoma mansoni hypothetical protein 0.0021 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.02 0.0345 0.0543
Brugia malayi Calcium binding EGF domain containing protein 0.0326 0.0582 0.0928
Onchocerca volvulus 0.0026 0.0018 0.0009
Echinococcus granulosus aminopeptidase N 0.0119 0.0193 0.0213
Schistosoma mansoni hemicentin 0.0021 0.0008 0.0025
Schistosoma mansoni laminin gamma-3 chain 0.0326 0.0582 0.1784
Loa Loa (eye worm) CAMK protein kinase 0.0021 0.0008 0.0004
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0064 0.007
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0086 0.0131 0.0304
Echinococcus granulosus Netrin receptor DCC 0.0021 0.0008 0.0009
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.02 0.0345 0.1059
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0005 0.0016
Echinococcus granulosus microtubule associated protein 2 0.1563 0.2903 0.3202
Onchocerca volvulus 0.0022 0.001 0.0002
Brugia malayi Lethal protein 805 0.0021 0.0008 0.0013
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0026 0.0018 0.002
Schistosoma mansoni hypothetical protein 0.0074 0.0109 0.0333
Echinococcus multilocularis leucyl aminopeptidase 0.0021 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Schistosoma mansoni cercarial elastase (S01 family) 0.02 0.0345 0.1059
Schistosoma mansoni cercarial elastase (S01 family) 0.02 0.0345 0.1059
Echinococcus granulosus nephrin 0.0021 0.0008 0.0009
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0021 0.0008 0.0009
Brugia malayi Matrixin family protein 0.1275 0.2362 0.3768
Schistosoma mansoni amine GPCR 0.0026 0.0018 0.0054
Onchocerca volvulus 0.0326 0.0582 0.0574
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0018 0.0054
Echinococcus granulosus endothelin converting enzyme 1 0.0285 0.0504 0.0556
Brugia malayi Cathepsin L-like precursor 0.0022 0.001 0.0016
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.003 0.0025 0.0058
Loa Loa (eye worm) matrixin family protein 0.2766 0.5159 0.8228
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.0364 0.0572
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.001 0.0235
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0021 0.0008 0.0004
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0071 0.0102 0.0154
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0018 0.0019
Echinococcus granulosus subfamily M12B unassigned peptidase 0.016 0.027 0.0297
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Echinococcus multilocularis bloom syndrome protein 0.002 0.0007 0.0007
Brugia malayi Trypsin family protein 0.02 0.0345 0.0551
Echinococcus multilocularis rhodopsin orphan GPCR 0.0026 0.0018 0.0019
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0021 0.0008 0.0009
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0069 0.01 0.0305
Loa Loa (eye worm) hypothetical protein 0.0211 0.0365 0.0573
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0021 0.0009 0.0054
Brugia malayi Cathepsin L-like precursor 0.0022 0.001 0.0016
Brugia malayi Fibronectin type III domain containing protein 0.0021 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0141 0.0234 0.0365
Echinococcus multilocularis neuropeptide receptor A26 0.0026 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0285 0.0504 0.0804
Echinococcus granulosus rhodopsin orphan GPCR 0.0026 0.0018 0.0019
Echinococcus granulosus neurogenic locus protein delta 0.0326 0.0582 0.0642
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0008 0.0013
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0023 0.0012 0.0036
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Echinococcus multilocularis slit 2 protein 0.0326 0.0582 0.0642
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.0064 0.0094
Onchocerca volvulus 0.0026 0.0018 0.0009
Loa Loa (eye worm) hypothetical protein 0.013 0.0213 0.0331
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Echinococcus granulosus slit 2 protein 0.0326 0.0582 0.0642
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0005 0.0006
Schistosoma mansoni notch 0.0326 0.0582 0.1784
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0064 0.0196
Brugia malayi Fibronectin type III domain containing protein 0.0021 0.0008 0.0013
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.0173 0.0401
Loa Loa (eye worm) hypothetical protein 0.0326 0.0582 0.092
Schistosoma mansoni opsin-like receptor 0.0026 0.0018 0.0054
Brugia malayi hypothetical protein 0.0026 0.0018 0.0028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0022 0.001 0.0235
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0037 0.0113
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0021 0.0008 0.0009
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0005 0.0016
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0026 0.0018 0.0019
Loa Loa (eye worm) hypothetical protein 0.02 0.0345 0.0543
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0022 0.001 0.0011
Echinococcus granulosus neurogenic locus notch protein 0.0326 0.0582 0.0642
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Brugia malayi Dopamine receptor protein 2 0.0026 0.0018 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.001 0.006
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0007 0.004
Trypanosoma brucei trypanothione reductase 0.0048 0.0059 0.0359
Brugia malayi Calcium binding EGF domain containing protein 0.0326 0.0582 0.0928
Echinococcus granulosus EG95 0.0021 0.0008 0.0009
Schistosoma mansoni cell adhesion molecule 0.0021 0.0008 0.0025
Brugia malayi Calcium binding EGF domain containing protein 0.0326 0.0582 0.0928
Schistosoma mansoni notch 0.0326 0.0582 0.1784
Schistosoma mansoni nephrin 0.0021 0.0008 0.0025
Echinococcus granulosus protein jagged 1 0.0326 0.0582 0.0642
Echinococcus multilocularis neurogenic locus protein delta 0.0326 0.0582 0.0642
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0071 0.0102 0.0312
Onchocerca volvulus 0.02 0.0345 0.0337
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0026 0.0018 0.0019
Schistosoma mansoni factor for adipocyte differentiation 0.0021 0.0008 0.0025
Brugia malayi follicle stimulating hormone receptor 0.0026 0.0018 0.0028
Toxoplasma gondii calcium binding egf domain-containing protein 0.0071 0.0102 0.0236
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0173 0.0401
Brugia malayi notch-like transmembrane receptor 0.0326 0.0582 0.0928
Brugia malayi hypothetical protein 0.0021 0.0008 0.0013
Schistosoma mansoni cpg binding protein 0.0033 0.0032 0.0097
Onchocerca volvulus 0.0326 0.0582 0.0574
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0063 0.0101
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0027 0.0082
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.0196 0.0453
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0026 0.0018 0.0054
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0106 0.0169 0.039
Echinococcus multilocularis thyroid hormone receptor alpha 0.0137 0.0226 0.0249
Echinococcus granulosus dro:myosuppressin receptor 0.0026 0.0018 0.0019
Onchocerca volvulus Cathepsin L homolog 0.0022 0.001 0.0002
Entamoeba histolytica cysteine protease, putative 0.0022 0.001 0.1435
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.0196 0.0453
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.02 0.0345 0.1059
Mycobacterium leprae PROBABLE HYDROLASE 0.1491 0.2766 0.6396
Brugia malayi Cathepsin L-like precursor 0.0022 0.001 0.0016
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0021 0.0009 0.0054
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0236 0.0411 0.1261
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0005 0.0126
Brugia malayi hypothetical protein 0.0019 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0007 0.0002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0026 0.0018 0.0054
Brugia malayi Dopamine receptor 0.0026 0.0018 0.0028
Echinococcus multilocularis lamin 0.0027 0.002 0.0022
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0007 0.0007
Brugia malayi PXA domain containing protein 0.0019 0.0005 0.0009
Brugia malayi RE15519p 0.0026 0.0018 0.0028
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Echinococcus granulosus neuropeptide Y receptor 0.0026 0.0018 0.0019
Echinococcus granulosus anosmin 1 0.0021 0.0008 0.0009
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0021 0.0009 0.0054
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0005 0.0009
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0005 0.0006
Schistosoma mansoni titin 0.0021 0.0008 0.0025
Plasmodium vivax SET domain protein, putative 0.0031 0.0027 0.0062
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0026 0.0018 0.0019
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0005 0.0006
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0144 0.0239 0.0733
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0022 0.001 0.0007
Loa Loa (eye worm) peptidase family M1 containing protein 0.0097 0.015 0.0231
Loa Loa (eye worm) hypothetical protein 0.02 0.0345 0.0543
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.002
Onchocerca volvulus 0.02 0.0345 0.0337
Trypanosoma brucei Aminopeptidase M1, putative 0.0035 0.0035 0.0215
Loa Loa (eye worm) hypothetical protein 0.0021 0.0008 0.0004
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.0883 0.1626 1
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0007 0.0011
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0826 0.1519 0.1675
Brugia malayi Calcium binding EGF domain containing protein 0.0071 0.0102 0.0163
Schistosoma mansoni ADAMTS14 peptidase (M12 family) 0.0029 0.0023 0.0071
Echinococcus multilocularis Fibronectin type III domain containing protein 0.0021 0.0008 0.0009
Onchocerca volvulus 0.0026 0.0018 0.0009

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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