Detailed information for compound 676661

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 350.242 | Formula: C17H17Cl2N3O
  • H donors: 0 H acceptors: 0 LogP: 4.31 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCn1c(=N)n(c2c1cccc2)CCOc1ccc(cc1Cl)Cl
  • InChi: 1S/C17H17Cl2N3O/c1-2-21-14-5-3-4-6-15(14)22(17(21)20)9-10-23-16-8-7-12(18)11-13(16)19/h3-8,11,20H,2,9-10H2,1H3
  • InChiKey: CTXUFJCEJBOONW-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica cysteine proteinase, putative 0.0085 0.0042 0.0436
Brugia malayi hypothetical protein 0.0024 0.0001 0.0012
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.012 0.0064 0.0676
Schistosoma mansoni alpha-glucosidase 0.0137 0.0075 0.0795
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0674 0.0427 0.0427
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0018 0.0136
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0002 0.0022
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0014 0.0106
Brugia malayi Carboxylesterase family protein 0.0069 0.0031 0.0322
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.012 0.0064 0.0064
Toxoplasma gondii cathepsin CPL 0.0085 0.0042 0.0436
Brugia malayi Cathepsin L-like precursor 0.0028 0.0004 0.0042
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0009 0.0091
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0085 0.0042 0.0436
Onchocerca volvulus DNA topoisomerase 2 homolog 0.1119 0.0718 1
Schistosoma mansoni gliotactin 0.0069 0.0031 0.0325
Brugia malayi Pre-SET motif family protein 0.0068 0.003 0.0315
Brugia malayi beta-lactamase family protein 0.0043 0.0014 0.0148
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.008 0.0038 0.0398
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0085 0.0042 0.0439
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0009 0.0091
Echinococcus multilocularis lamin dm0 0.0113 0.006 0.0627
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0042 0.0436
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.0029 0.0304
Echinococcus multilocularis cathepsin L 0.0044 0.0015 0.0151
Schistosoma mansoni hypothetical protein 0.0024 0.0001 0.0015
Leishmania major basic transcription factor 3a, putative 0.0037 0.001 0.0073
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.0021 0.0218
Entamoeba histolytica heat shock protein 90, putative 0.02 0.0116 0.1227
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0085 0.0042 0.0436
Echinococcus granulosus heat shock protein 90 0.02 0.0116 0.1227
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0009 0.0091
Echinococcus granulosus acetylcholinesterase 0.0407 0.0252 0.2657
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0014 0.0148
Leishmania major cathepsin L-like protease 0.0325 0.0198 0.1499
Echinococcus multilocularis microtubule associated protein 2 0.1404 0.0904 0.9546
Trypanosoma cruzi heat shock protein 85, putative 0.008 0.0038 0.0286
Loa Loa (eye worm) hypothetical protein 0.0024 0.0001 0.0015
Plasmodium vivax vivapain-1 0.0044 0.0015 0.0111
Schistosoma mansoni ap endonuclease 0.0022 0 0.0003
Loa Loa (eye worm) hypothetical protein 0.0111 0.0058 0.0615
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0009 0.0091
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0085 0.0042 0.0436
Mycobacterium ulcerans hypothetical protein 0.0043 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0028 0.0004 0.0045
Entamoeba histolytica cysteine protease, putative 0.0044 0.0015 0.0151
Onchocerca volvulus Cathepsin L homolog 0.0085 0.0042 0.0561
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.012 0.0064 0.0064
Mycobacterium tuberculosis Probable sensor protein KdpD 0.012 0.0064 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0325 0.0198 0.1499
Trichomonas vaginalis receptor histidine kinase, putative 0.012 0.0064 0.0676
Plasmodium vivax DNA gyrase subunit A, putative 0.0674 0.0427 0.3306
Trichomonas vaginalis endoplasmin, putative 0.0161 0.0091 0.096
Mycobacterium tuberculosis Two component sensor kinase MprB 0.012 0.0064 0.0064
Brugia malayi Carboxylesterase family protein 0.0069 0.0031 0.0322
Schistosoma mansoni cathepsin F (C01 family) 0.0057 0.0023 0.0244
Trypanosoma cruzi heat shock protein 90, putative 0.02 0.0116 0.088
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0031 0.0234
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.009 0.0945
Trypanosoma cruzi heat shock protein 90, putative 0.0159 0.009 0.0677
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.0069 0.0725
Loa Loa (eye worm) acetylcholinesterase 1 0.0407 0.0252 0.2659
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0042 0.0436
Trypanosoma brucei heat shock protein, putative 0.02 0.0116 0.088
Loa Loa (eye worm) hypothetical protein 0.0049 0.0018 0.0192
Leishmania major heat shock protein, putative 0.0041 0.0013 0.0094
Onchocerca volvulus 0.0043 0.0014 0.018
Entamoeba histolytica acyl-CoA synthetase, putative 0.007 0.0031 0.033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0325 0.0198 0.1499
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.012 0.0064 0.0064
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0009 0.0091
Trypanosoma brucei glucosidase, putative 0.0035 0.0009 0.0065
Brugia malayi Carboxylesterase family protein 0.0069 0.0031 0.0322
Trypanosoma brucei heat shock protein 90, putative 0.02 0.0116 0.088
Trypanosoma brucei heat shock protein 90, putative 0.02 0.0116 0.088
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0127 0.1337
Echinococcus granulosus chromobox protein 1 0.0073 0.0034 0.0353
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0014 0.0106
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0009 0.0065
Onchocerca volvulus 0.0032 0.0007 0.0077
Schistosoma mansoni chromobox protein 0.0073 0.0034 0.0356
Onchocerca volvulus 0.0069 0.0031 0.041
Echinococcus granulosus RUN 0.0024 0.0001 0.0012
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.012 0.0064 0.0485
Loa Loa (eye worm) beta-lactamase 0.0043 0.0014 0.015
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.008 0.0038 0.0024
Onchocerca volvulus 0.0085 0.0042 0.0561
Loa Loa (eye worm) hypothetical protein 0.0054 0.0021 0.0226
Schistosoma mansoni hypothetical protein 0.0696 0.0441 0.4656
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0085 0.0042 0.0439
Echinococcus granulosus cysteine protease 0.0044 0.0015 0.0151
Entamoeba histolytica cysteine proteinase, putative 0.0044 0.0015 0.0151
Echinococcus multilocularis heat shock protein 90 0.02 0.0116 0.1227
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0014 0.0148
Entamoeba histolytica cysteine protease, putative 0.0044 0.0015 0.0151
Mycobacterium ulcerans DNA gyrase subunit B 0.1994 0.129 0.129
Trichomonas vaginalis receptor histidine kinase, putative 0.012 0.0064 0.0676
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.021
Loa Loa (eye worm) hypothetical protein 0.0085 0.0042 0.0439
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.012 0.0064 0.0064
Brugia malayi CXXC zinc finger family protein 0.0059 0.0024 0.0252
Brugia malayi cathepsin L-like precursor 0.0057 0.0023 0.0241
Mycobacterium ulcerans carboxylesterase, LipT 0.0069 0.0031 0.0031
Mycobacterium tuberculosis Conserved protein 0.0043 0.0014 0.0014
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.0212
Loa Loa (eye worm) hypothetical protein 0.0069 0.0031 0.033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0002 0.0022
Trypanosoma brucei DNA topoisomerase III, putative 0.0157 0.0089 0.0668
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.021
Mycobacterium ulcerans DNA gyrase subunit A 0.0674 0.0427 0.0427
Treponema pallidum heat shock protein 90 0.008 0.0038 0.0292
Toxoplasma gondii heat shock protein HSP90 0.02 0.0116 0.1227
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.0021 0.0156
Plasmodium vivax multidomain scavenger receptor, putative 0.0024 0.0001 0.0009
Echinococcus multilocularis survival motor neuron protein 1 0.0479 0.0299 0.3158
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0044 0.0015 0.0153
Entamoeba histolytica cysteine proteinase, putative 0.0044 0.0015 0.0151
Loa Loa (eye worm) hypothetical protein 0.0043 0.0014 0.015
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.007 0.0031 0.0332
Brugia malayi kinase, mitochondrial precursor 0.012 0.0064 0.0676
Echinococcus multilocularis zinc finger protein 0.0024 0.0001 0.0013
Brugia malayi glutaminase DH11.1 0.032 0.0195 0.2056
Echinococcus granulosus heat shock protein 0.02 0.0116 0.1227
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0031 0.0234
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0157 0.0089 0.0668
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.012 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0069 0.0031 0.0325
Mycobacterium ulcerans two component regulator - sensor kinase 0.012 0.0064 0.0064
Trypanosoma cruzi cruzipain precursor, putative 0.0325 0.0198 0.1499
Mycobacterium ulcerans hypothetical protein 0.007 0.0031 0.0031
Onchocerca volvulus 0.0098 0.005 0.0675
Echinococcus multilocularis cysteine protease 0.0085 0.0042 0.0436
Leishmania major cathepsin L-like protease 0.0325 0.0198 0.1499
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0325 0.0198 0.1499
Onchocerca volvulus Cathepsin F homolog 0.0085 0.0042 0.0561
Trypanosoma cruzi Heat shock protein 83, putative 0.02 0.0116 0.088
Trypanosoma brucei heat shock protein 84, putative 0.0041 0.0013 0.0094
Loa Loa (eye worm) hypothetical protein 0.0028 0.0004 0.0045
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.0029 0.0304
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.0052 0.0549
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0009 0.0065
Trypanosoma cruzi DNA topoisomerase II, putative 0.1313 0.0844 0.6394
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0042 0.0436
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0041 0.0013 0.0131
Echinococcus granulosus carboxylesterase 5A 0.0407 0.0252 0.2657
Toxoplasma gondii heat shock protein 90, putative 0.02 0.0116 0.1227
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.012 0.0064 0.0485
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.007 0.0031 0.0031
Trichomonas vaginalis heat shock protein, putative 0.008 0.0038 0.0398
Echinococcus granulosus tumor protein p63 0.0408 0.0253 0.2666
Loa Loa (eye worm) hypothetical protein 0.0057 0.0023 0.0244
Onchocerca volvulus DNA topoisomerase 2 homolog 0.1119 0.0718 1
Schistosoma mansoni lamin 0.0113 0.006 0.0629
Onchocerca volvulus 0.0085 0.0042 0.0561
Schistosoma mansoni pyruvate dehydrogenase 0.012 0.0064 0.0679
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0007 0.0069
Brugia malayi Doublecortin family protein 0.0024 0.0001 0.0012
Brugia malayi MAP kinase sur-1 0.0054 0.0021 0.0218
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0001 0.0012
Plasmodium falciparum cysteine proteinase falcipain 1 0.0044 0.0015 0.0111
Schistosoma mansoni endoplasmin 0.02 0.0116 0.123
Echinococcus multilocularis neuropeptide s receptor 0.0489 0.0305 0.3223
Brugia malayi intermediate filament protein 0.0113 0.006 0.0627
Trichomonas vaginalis glutaminase, putative 0.032 0.0195 0.2056
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0297 0.018 0.136
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0014 0.0014
Trypanosoma cruzi DNA topoisomerase III, putative 0.0157 0.0089 0.0668
Loa Loa (eye worm) hypothetical protein 0.0069 0.0031 0.0325
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0325 0.0198 0.1499
Schistosoma mansoni hypothetical protein 0.0032 0.0007 0.0072
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0002 0.0022
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0014 0.015
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.012 0.0064 0.0496
Echinococcus multilocularis endoplasmin 0.008 0.0038 0.0398
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0014 0.0014
Brugia malayi heat shock protein 90 0.02 0.0116 0.1227
Onchocerca volvulus 0.007 0.0031 0.042
Loa Loa (eye worm) hypothetical protein 0.0684 0.0433 0.4573
Schistosoma mansoni DNA topoisomerase II 0.147 0.0947 1
Brugia malayi beta-NAC-like protein 0.0037 0.001 0.0101
Brugia malayi hypothetical protein 0.0032 0.0007 0.0068
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0003 0.0037
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0085 0.0042 0.0436
Loa Loa (eye worm) hypothetical protein 0.007 0.0031 0.0332
Entamoeba histolytica transcription factor BTF3, putative 0.0037 0.001 0.0101
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0021 0.0156
Schistosoma mansoni transcription factor btf3 0.0037 0.001 0.0104
Loa Loa (eye worm) hypothetical protein 0.004 0.0012 0.0129
Brugia malayi Intermediate filament tail domain containing protein 0.0113 0.006 0.0627
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0046 0.0488
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0085 0.0042 0.0436
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0007 0.0072
Giardia lamblia DNA topoisomerase III 0.0157 0.0089 0.1016
Plasmodium vivax ataxin-2 like protein, putative 0.0049 0.0018 0.0139
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0014 0.015
Toxoplasma gondii Hsp90 domain-containing protein 0.0041 0.0013 0.0131
Onchocerca volvulus 0.0069 0.0031 0.041
Echinococcus granulosus GPCR family 2 0.0032 0.0007 0.0069
Leishmania major DNA topoisomerase III, putative 0.0157 0.0089 0.0668
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0014 0.0148
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.012 0.0064 0.0349
Schistosoma mansoni bromodomain containing protein 0.007 0.0032 0.0333
Schistosoma mansoni cathepsin F (C01 family) 0.0085 0.0042 0.0439
Echinococcus granulosus neuroligin 0.0069 0.0031 0.0322
Mycobacterium ulcerans beta-lactamase 0.0043 0.0014 0.0014
Trichomonas vaginalis heat shock protein, putative 0.008 0.0038 0.0398
Brugia malayi hypothetical protein 0.0069 0.0031 0.0322
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0031 0.0236
Plasmodium falciparum LCCL domain-containing protein 0.0024 0.0001 0.0009
Entamoeba histolytica cysteine protease, putative 0.0044 0.0015 0.0151
Loa Loa (eye worm) fibroinase 0.0085 0.0042 0.0439
Brugia malayi chromobox protein homolog 3 0.0041 0.0013 0.0131
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0031 0.0031
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.012 0.0064 0.0676
Echinococcus granulosus para nitrobenzyl esterase 0.0069 0.0031 0.0322
Mycobacterium tuberculosis Integral membrane indolylacetylinositol arabinosyltransferase EmbB (arabinosylindolylacetylinositol synthase) 1.531 1 1
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.012 0.0064 0.0064
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0069 0.0031 0.0325
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0085 0.0042 0.0436
Echinococcus granulosus microtubule associated protein 2 0.1404 0.0904 0.9546
Loa Loa (eye worm) hypothetical protein 0.0149 0.0083 0.0876
Loa Loa (eye worm) hypothetical protein 0.0069 0.0031 0.0325
Mycobacterium ulcerans integral membrane indolylacetylinositol arabinosyltransferase EmbB 1.531 1 1
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.012 0.1261
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0157 0.0089 0.0932
Loa Loa (eye worm) hypothetical protein 0.0407 0.0252 0.2659
Trypanosoma brucei PAB1-binding protein , putative 0.0049 0.0018 0.0136
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0948 0.0606 0.6398
Loa Loa (eye worm) hypothetical protein 0.0048 0.0017 0.0183
Schistosoma mansoni heat shock protein 0.0041 0.0013 0.0133
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0021 0.0156
Onchocerca volvulus 0.0057 0.0023 0.0303
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.012 0.0064 0.0064
Trypanosoma brucei transcription factor BTF3, putative 0.0037 0.001 0.0073
Loa Loa (eye worm) hypothetical protein 0.0043 0.0014 0.015
Leishmania major heat shock protein 83-1 0.02 0.0116 0.088
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0031 0.0234
Plasmodium vivax basic transcription factor 3b, putative 0.0037 0.001 0.0074
Loa Loa (eye worm) hypothetical protein 0.0069 0.0031 0.0325
Echinococcus multilocularis rho GTPase activating protein 20 0.0157 0.0089 0.0932
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.012 0.0064 0.0676
Schistosoma mansoni survival motor neuron protein 0.0098 0.005 0.0525
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.0001 0.0012
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.007 0.0031 0.0031
Entamoeba histolytica DNA topoisomerase II, putative 0.147 0.0947 1
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.0021 0.0156
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.001 0.0073
Loa Loa (eye worm) heat shock protein 75 0.0041 0.0013 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.001 0.0101
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0021 0.0218
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0069 0.0031 0.0325
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0001 0.0012
Brugia malayi Carboxylesterase family protein 0.0407 0.0252 0.2657
Trypanosoma cruzi DNA topoisomerase III, putative 0.0157 0.0089 0.0668
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.007 0.0031 0.0017
Loa Loa (eye worm) hypothetical protein 0.007 0.0031 0.0332
Schistosoma mansoni neuroligin 3 (S09 family) 0.0069 0.0031 0.0325
Echinococcus granulosus DNA topoisomerase 2 alpha 0.147 0.0947 1
Schistosoma mansoni lipoxygenase 0.01 0.0051 0.0538
Echinococcus multilocularis cpg binding protein 0.0064 0.0028 0.0289
Brugia malayi cytoplasmic intermediate filament protein 0.006 0.0025 0.0265
Trichomonas vaginalis heat shock protein, putative 0.02 0.0116 0.1227
Trypanosoma cruzi DNA topoisomerase II, putative 0.1313 0.0844 0.6394
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0014 0.0014
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.008 0.0038 0.0286
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0044 0.0015 0.0108
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.012 0.0064 0.0064
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.006 0.0025 0.0268
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0304 0.0184 0.1945
Echinococcus multilocularis cathepsin L cysteine protease 0.0085 0.0042 0.0436
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.019 0.2002
Toxoplasma gondii heat shock protein 75, putative 0.0041 0.0013 0.0131
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.001 0.0073
Leishmania major cathepsin L-like protease 0.0085 0.0042 0.0313
Brugia malayi DNA topoisomerase III beta-1 0.0157 0.0089 0.0932
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.012 0.0064 0.0676
Brugia malayi Bromodomain containing protein 0.004 0.0012 0.0126
Toxoplasma gondii ABC1 family protein 0.0043 0.0014 0.0148
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0046 0.0488
Entamoeba histolytica cysteine protease, putative 0.0044 0.0015 0.0151
Entamoeba histolytica hypothetical protein 0.0037 0.001 0.0101
Echinococcus granulosus transcription factor btf3 0.0037 0.001 0.0101
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.2041 0.1321 1
Echinococcus granulosus zinc finger protein 0.0024 0.0001 0.0013
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.147 0.0947 1
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0157 0.0089 0.0932
Onchocerca volvulus 0.0085 0.0042 0.0561
Echinococcus granulosus cathepsin L 0.0044 0.0015 0.0151
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.019 0.2002
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0069 0.0031 0.0322
Plasmodium vivax DNA topoisomerase II, putative 0.147 0.0947 0.7339
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.009 0.0945
Brugia malayi Bromodomain containing protein 0.0082 0.004 0.0415
Plasmodium vivax DNA gyrase subunit B, putative 0.1994 0.129 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0085 0.0042 0.0436
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.012 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.006 0.0025 0.0263
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0325 0.0198 0.1499
Mycobacterium tuberculosis Integral membrane indolylacetylinositol arabinosyltransferase EmbA (arabinosylindolylacetylinositol synthase) 1.531 1 1
Plasmodium vivax vivapain-3 0.0044 0.0015 0.0111
Trypanosoma brucei heat shock protein, putative 0.02 0.0116 0.088
Toxoplasma gondii DNA topoisomerase 2, putative 0.147 0.0947 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.021
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0142 0.0079 0.0831
Brugia malayi GRF zinc finger family protein 0.0157 0.0089 0.0932
Loa Loa (eye worm) hypothetical protein 0.0074 0.0034 0.0364
Trypanosoma cruzi heat shock protein 90, putative 0.008 0.0038 0.0286
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0007 0.0069
Leishmania major cathepsin L-like protease 0.0085 0.0042 0.0313
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0046 0.0488
Loa Loa (eye worm) hypothetical protein 0.0069 0.0031 0.0325
Echinococcus multilocularis neuroligin 0.0069 0.0031 0.0322
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0068 0.003 0.0315
Mycobacterium ulcerans heat shock protein 90 0.008 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0023 0.0241
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0069 0.0031 0.0031
Plasmodium falciparum DNA gyrase subunit B 0.1994 0.129 1
Schistosoma mansoni alpha-glucosidase 0.0137 0.0075 0.0795
Echinococcus granulosus heat shock protein 90 0.008 0.0038 0.0398
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.008 0.0038 0.0401
Echinococcus multilocularis chromobox protein 1 0.0073 0.0034 0.0353
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0085 0.0042 0.032
Leishmania major cysteine peptidase A (CPA) 0.0085 0.0042 0.0313
Schistosoma mansoni hypothetical protein 0.0834 0.0531 0.5608
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.0021 0.0218
Plasmodium falciparum acyl-CoA synthetase 0.0052 0.002 0.0153
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0031 0.0234
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0046 0.0488
Schistosoma mansoni alpha glucosidase 0.0035 0.0009 0.0094
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0009 0.0091
Treponema pallidum chemotaxis histidine kinase (cheA) 0.012 0.0064 0.0496
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0407 0.0252 0.2659
Schistosoma mansoni heat shock protein 0.02 0.0116 0.123
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0018 0.0136
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0069 0.0031 0.0322
Loa Loa (eye worm) glutaminase 2 0.032 0.0195 0.2058
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0005 0.0048
Trypanosoma brucei DNA topoisomerase ii 0.2041 0.1321 1
Loa Loa (eye worm) glutaminase 0.032 0.0195 0.2058
Giardia lamblia DNA topoisomerase III 0.0157 0.0089 0.1016
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0085 0.0042 0.0436
Schistosoma mansoni cpg binding protein 0.0064 0.0028 0.0291
Brugia malayi AMP-binding enzyme family protein 0.007 0.0031 0.033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.0015 0.0151
Entamoeba histolytica acyl-coA synthetase, putative 0.007 0.0031 0.033
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0157 0.0089 0.0932
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0015 0.0108
Giardia lamblia Grp94/Hsp90 0.008 0.0038 0.0434
Onchocerca volvulus 0.0085 0.0042 0.0561
Echinococcus granulosus acetylcholinesterase 0.0407 0.0252 0.2657
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.012 0.0064 0.005
Giardia lamblia Pms1-like protein 0.012 0.0064 0.0738
Entamoeba histolytica cysteine protease, putative 0.0044 0.0015 0.0151
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0041 0.0013 0.0131
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0304 0.0184 0.1945
Trypanosoma brucei DNA topoisomerase IA, putative 0.0157 0.0089 0.0668
Brugia malayi Pre-SET motif family protein 0.0465 0.029 0.3057
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0085 0.0042 0.0436
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.012 0.1261
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.012 0.0064 0.0676
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0009 0.0094
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.0021 0.0156
Schistosoma mansoni hypothetical protein 0.0032 0.0007 0.0072
Brugia malayi Papain family cysteine protease containing protein 0.0085 0.0042 0.0436
Loa Loa (eye worm) hypothetical protein 0.0407 0.0252 0.2659
Onchocerca volvulus 0.0069 0.0031 0.041
Plasmodium vivax unspecified product 0.0028 0.0004 0.0031
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0072
Leishmania major heat shock protein 83-1 0.02 0.0116 0.088
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0674 0.0427 0.4505
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0046 0.049
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0018 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0042 0.0436
Loa Loa (eye worm) MH2 domain-containing protein 0.0126 0.0068 0.0717
Plasmodium vivax unspecified product 0.0044 0.0015 0.0111
Loa Loa (eye worm) doublecortin family protein 0.0024 0.0001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0057 0.0023 0.0244
Loa Loa (eye worm) hypothetical protein 0.0069 0.0031 0.0325
Trypanosoma brucei protein kinase, putative 0.0054 0.0021 0.0156
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0042 0.0436
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.012 0.0064 0.0064
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0002 0.0022
Leishmania major cathepsin L-like protease 0.0085 0.0042 0.0313
Loa Loa (eye worm) hypothetical protein 0.0043 0.0014 0.015
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0014 0.0148
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0012 0.0125
Echinococcus granulosus lamin 0.0113 0.006 0.0627
Trypanosoma brucei DNA topoisomerase III, putative 0.0157 0.0089 0.0668
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0014 0.0108
Entamoeba histolytica cysteine proteinase, putative 0.0044 0.0015 0.0151
Trypanosoma cruzi cysteine protease, putative 0.0044 0.0015 0.0108
Plasmodium falciparum cysteine proteinase falcipain 3 0.0085 0.0042 0.032
Echinococcus multilocularis cathepsin L cysteine protease 0.0085 0.0042 0.0436
Trypanosoma brucei heat shock protein, putative 0.02 0.0116 0.088
Loa Loa (eye worm) endoplasmin 0.02 0.0116 0.123
Echinococcus multilocularis heat shock protein 90 0.008 0.0038 0.0398
Entamoeba histolytica cysteine proteinase, putative 0.0057 0.0023 0.0241
Loa Loa (eye worm) hypothetical protein 0.0149 0.0083 0.0876
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.009 0.0945
Schistosoma mansoni rab6-interacting 0.0024 0.0001 0.0015
Brugia malayi Carboxylesterase family protein 0.0407 0.0252 0.2657
Entamoeba histolytica DNA topoisomerase III, putative 0.0157 0.0089 0.0932
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.012 0.0064 0.0064
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.007 0.0031 0.0031
Brugia malayi beta-lactamase family protein 0.0043 0.0014 0.0148
Giardia lamblia Heat shock protein HSP 90-alpha 0.02 0.0116 0.1338
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.0021 0.0218
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0015 0.0108
Echinococcus granulosus cathepsin L cysteine protease 0.0044 0.0015 0.0151
Onchocerca volvulus 0.0043 0.0014 0.018
Entamoeba histolytica cysteine protease, putative 0.0044 0.0015 0.0151
Entamoeba histolytica cysteine protease, putative 0.0044 0.0015 0.0151
Trichomonas vaginalis set domain proteins, putative 0.0529 0.0332 0.3499
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0157 0.0089 0.0932
Echinococcus granulosus cathepsin l1 0.0085 0.0042 0.0436
Trypanosoma brucei developmentally regulated phosphoprotein 0.012 0.0064 0.0485
Trichomonas vaginalis heat shock protein, putative 0.0161 0.0091 0.096
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0031 0.0236
Leishmania major developmentally regulated phosphoprotein-like protein 0.012 0.0064 0.0485
Schistosoma mansoni endoplasmin 0.02 0.0116 0.123
Loa Loa (eye worm) hypothetical protein 0.0041 0.0013 0.0134
Echinococcus multilocularis RUN 0.0024 0.0001 0.0012
Echinococcus granulosus intermediate filament protein 0.0113 0.006 0.0627
Onchocerca volvulus 0.0113 0.006 0.0812
Plasmodium vivax DNA topoisomerase 3, putative 0.0157 0.0089 0.0684
Schistosoma mansoni intermediate filament proteins 0.0113 0.006 0.0629
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.0168 0.0167
Brugia malayi Cathepsin L-like cysteine proteinase 0.0057 0.0023 0.0241
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0042 0.0436
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.012 0.0064 0.0676
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0157 0.0089 0.0932
Chlamydia trachomatis DNA gyrase subunit A 0.0278 0.0168 0.1164
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0021 0.0218
Echinococcus granulosus neuropeptide s receptor 0.0489 0.0305 0.3223
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0015 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0013 0.0131
Chlamydia trachomatis DNA gyrase subunit A 0.0674 0.0427 0.3202
Onchocerca volvulus 0.0113 0.006 0.0812
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.012 0.0064 0.0676
Echinococcus granulosus histone lysine methyltransferase setb 0.0086 0.0042 0.0439
Mycobacterium tuberculosis Possible two component sensor kinase 0.012 0.0064 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0325 0.0198 0.1499
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0014 0.0014
Entamoeba histolytica cysteine protease, putative 0.0044 0.0015 0.0151
Entamoeba histolytica acyl-CoA synthetase, putative 0.007 0.0031 0.033
Leishmania major heat shock protein 83-1 0.02 0.0116 0.088
Chlamydia trachomatis DNA topoisomerase I 0.0157 0.0089 0.054
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.012 0.0064 0.0676
Schistosoma mansoni loxhd1 0.0024 0.0001 0.0015
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.0021 0.0156
Echinococcus granulosus cathepsin l cysteine peptidase 0.0085 0.0042 0.0436
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0009 0.0091
Leishmania major DNA topoisomerase ii 0.1313 0.0844 0.6394
Trypanosoma brucei heat shock protein, putative 0.02 0.0116 0.088
Entamoeba histolytica cysteine protease, putative 0.0044 0.0015 0.0151
Leishmania major 4-coumarate:coa ligase-like protein 0.007 0.0031 0.0236
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0086 0.0042 0.0442
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.1994 0.129 1
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.012 0.0064 0.0496
Trypanosoma brucei heat shock protein, putative 0.02 0.0116 0.088
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.0021 0.0218
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.0021 0.0156
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0157 0.0089 0.0934
Echinococcus granulosus survival motor neuron protein 1 0.0479 0.0299 0.3158
Trypanosoma cruzi cysteine peptidase, putative 0.0028 0.0004 0.003
Echinococcus granulosus lamin dm0 0.0113 0.006 0.0627
Echinococcus multilocularis neuropeptide receptor A26 0.0489 0.0305 0.3223
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0007 0.0069
Toxoplasma gondii NAC domain-containing protein 0.0037 0.001 0.0101
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0001 0.0012
Brugia malayi hypothetical protein 0.0479 0.0299 0.3158
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0021 0.022
Loa Loa (eye worm) hypothetical protein 0.0028 0.0004 0.0045
Leishmania major heat shock protein 83-1 0.02 0.0116 0.088
Plasmodium falciparum endoplasmin, putative 0.0161 0.0091 0.0704
Leishmania major hypothetical protein, conserved 0.0043 0.0014 0.0106
Trypanosoma cruzi cysteine peptidase, putative 0.0044 0.0015 0.0108
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.012 0.0064 0.0064
Mycobacterium tuberculosis Probable two component sensor kinase 0.012 0.0064 0.0064
Trichomonas vaginalis esterase, putative 0.0043 0.0014 0.0148
Schistosoma mansoni lipoxygenase 0.0142 0.0079 0.0834
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0157 0.0089 0.0934
Onchocerca volvulus 0.0092 0.0046 0.0622
Giardia lamblia DNA topoisomerase II 0.135 0.0869 1
Loa Loa (eye worm) hypothetical protein 0.0777 0.0494 0.5218
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0018 0.0018
Entamoeba histolytica cysteine protease, putative 0.0044 0.0015 0.0151
Mycobacterium ulcerans lipase LipD 0.0043 0.0014 0.0014
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0041 0.0013 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0085 0.0042 0.0436
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0064 0.0028 0.029
Leishmania major DNA topoisomerase III, putative 0.0157 0.0089 0.0668
Echinococcus granulosus transcription factor Dp 1 0.004 0.0012 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.0015 0.0151
Schistosoma mansoni rab6-interacting 0.0024 0.0001 0.0015
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0054 0.0021 0.0223
Entamoeba histolytica cysteine proteinase 1, putative 0.0044 0.0015 0.0151
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0312 0.019 0.2004
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0054 0.0021 0.0223
Loa Loa (eye worm) hypothetical protein 0.0684 0.0433 0.4573
Brugia malayi AMP-binding enzyme family protein 0.007 0.0031 0.033
Leishmania major DNA topoisomerase 1A 0.0157 0.0089 0.0668
Mycobacterium tuberculosis Carboxylesterase LipT 0.0069 0.0031 0.0031
Entamoeba histolytica cysteine proteinase, putative 0.0085 0.0042 0.0436
Loa Loa (eye worm) hypothetical protein 0.0057 0.0023 0.0244
Trichomonas vaginalis spcc417.12 protein, putative 0.0069 0.0031 0.0322
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0007 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.001 0.0101
Brugia malayi Papain family cysteine protease containing protein 0.0044 0.0015 0.0151
Onchocerca volvulus 0.008 0.0038 0.051
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0011 0.0108
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0069 0.0031 0.0322
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.0021 0.0218
Mycobacterium ulcerans DNA topoisomerase I 0.0157 0.0089 0.0088
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0325 0.0198 0.1499
Echinococcus multilocularis dnaJ subfamily B 0.0834 0.0531 0.5607
Loa Loa (eye worm) hypothetical protein 0.0032 0.0007 0.0073
Plasmodium falciparum heat shock protein 90, putative 0.0041 0.0013 0.0096
Leishmania major heat shock protein 83-1 0.02 0.0116 0.088
Plasmodium vivax heat shock protein 86, putative 0.02 0.0116 0.0901
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0046 0.0488
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0042 0.0436
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0013 0.0131
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.009 0.0948
Trypanosoma cruzi cysteine peptidase, putative 0.0325 0.0198 0.1499
Leishmania major heat shock protein 83-1 0.02 0.0116 0.088
Plasmodium vivax heat shock protein, putative 0.0041 0.0013 0.0096
Leishmania major heat shock protein 83-1 0.02 0.0116 0.088
Mycobacterium leprae Probable two component sensor kinase MprB 0.012 0.0064 0.005
Trypanosoma brucei heat shock protein, putative 0.02 0.0116 0.088
Loa Loa (eye worm) hypothetical protein 0.0149 0.0083 0.0876
Brugia malayi Cathepsin L-like precursor 0.0085 0.0042 0.0436
Echinococcus granulosus BC026374 protein S09 family 0.0069 0.0031 0.0322
Brugia malayi Probable DNA topoisomerase II 0.147 0.0947 1
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0312 0.019 0.2002
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0009 0.0065
Brugia malayi hypothetical protein 0.0049 0.0018 0.0189
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0325 0.0198 0.1499
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.019 0.2002
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0009 0.0091
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0325 0.0198 0.1499
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0085 0.0042 0.0436
Loa Loa (eye worm) hypothetical protein 0.0777 0.0494 0.5218
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0098 0.005 0.0523
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.012 0.1261
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0086 0.0042 0.0442
Plasmodium vivax heat shock protein 90, putative 0.0041 0.0013 0.0096
Loa Loa (eye worm) TOPoisomerase family member 0.147 0.0947 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0014 0.015
Giardia lamblia Heat shock protein HSP 90-alpha 0.008 0.0038 0.0434
Mycobacterium leprae Probable integral membrane indolylacetylinositol arabinosyltransferase EmbB (arabinosylindolylacetylinositol synthase) 1.531 1 1
Onchocerca volvulus 0.0085 0.0042 0.0561
Echinococcus multilocularis GPCR, family 2 0.0032 0.0007 0.0069
Entamoeba histolytica heat shock protein 90, putative 0.02 0.0116 0.1227
Echinococcus multilocularis lamin 0.0113 0.006 0.0627
Echinococcus granulosus geminin 0.0696 0.0441 0.4655
Leishmania major heat shock protein 83-1 0.02 0.0116 0.088
Echinococcus multilocularis BC026374 protein (S09 family) 0.0069 0.0031 0.0322
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0001 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.012 0.1261
Schistosoma mansoni ap endonuclease 0.0022 0 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.019 0.2002
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0007 0.0069
Echinococcus multilocularis geminin 0.0696 0.0441 0.4655
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.0001 0.0012
Schistosoma mansoni polycystin 1-related 0.0024 0.0001 0.0015
Onchocerca volvulus 0.0059 0.0024 0.0317
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0086 0.0042 0.0439
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0031 0.0327
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0325 0.0198 0.1499
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0009 0.0091
Onchocerca volvulus 0.0529 0.0332 0.4608
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0325 0.0198 0.1499
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0465 0.029 0.3059
Brugia malayi Cathepsin L-like precursor 0.0085 0.0042 0.0436
Trypanosoma cruzi heat shock protein 85, putative 0.02 0.0116 0.088
Echinococcus multilocularis carboxylesterase 5A 0.0407 0.0252 0.2657
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.0052 0.0549
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0157 0.0089 0.0684
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0009 0.0091
Schistosoma mansoni hypothetical protein 0.0098 0.005 0.0525
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0031 0.0327
Onchocerca volvulus 0.006 0.0025 0.0328
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.008 0.0038 0.0038
Schistosoma mansoni hypothetical protein 0.0069 0.0031 0.033
Schistosoma mansoni hypothetical protein 0.0022 0 0.0003
Leishmania major heat shock protein 83-1 0.02 0.0116 0.088
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0085 0.0042 0.0436
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.1994 0.129 0.129
Mycobacterium ulcerans integral membrane indolylacetylinositol arabinosyltransferase EmbC 1.531 1 1
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0127 0.1337
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0042 0.0436
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.012 0.1261
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0046 0.049
Trichomonas vaginalis sensor histidine kinase, putative 0.012 0.0064 0.0676
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0042 0.0436
Trypanosoma cruzi heat shock protein, putative 0.0041 0.0013 0.0094
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0157 0.0089 0.0932
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.147 0.0947 1
Leishmania major heat shock protein 83-1 0.02 0.0116 0.088
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0009 0.0091
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0014 0.0148
Schistosoma mansoni acetylcholinesterase 0.0069 0.0031 0.0325
Loa Loa (eye worm) carboxylesterase 0.0069 0.0031 0.0325
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0157 0.0089 0.0074
Mycobacterium ulcerans putative regultory protein 0.012 0.0064 0.0064
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0018 0.0139
Brugia malayi Hsp90 protein 0.0041 0.0013 0.0131
Echinococcus granulosus cathepsin l1 0.0057 0.0023 0.0241
Entamoeba histolytica cysteine protease, putative 0.0085 0.0042 0.0436
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0014 0.0106
Brugia malayi DNA topoisomerase III 0.0157 0.0089 0.0932
Brugia malayi Carboxylesterase family protein 0.0069 0.0031 0.0322
Brugia malayi Cathepsin L-like precursor 0.0057 0.0023 0.0241
Mycobacterium leprae Probable two-component sensor kinase 0.012 0.0064 0.005
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0479 0.0299 0.316
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0009 0.0091
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.072 0.0456 0.0443
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0002 0.0022
Brugia malayi Papain family cysteine protease containing protein 0.0044 0.0015 0.0151
Loa Loa (eye worm) DNA topoisomerase III 0.0157 0.0089 0.0934
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0044 0.0015 0.0153
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0042 0.0436
Loa Loa (eye worm) ctsf protein 0.0085 0.0042 0.0439
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0046 0.049
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.012 0.0064 0.0064
Mycobacterium ulcerans glutaminase 0.032 0.0195 0.0195
Leishmania major hypothetical protein, conserved 0.0049 0.0018 0.0136
Loa Loa (eye worm) hypothetical protein 0.0086 0.0042 0.0442
Onchocerca volvulus Glucosylceramidase homolog 0.0205 0.012 0.1651
Onchocerca volvulus 0.0069 0.0031 0.041
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0002 0.0022
Loa Loa (eye worm) hypothetical protein 0.012 0.0064 0.0679
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.001 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0005 0.0048
Brugia malayi MH2 domain containing protein 0.0126 0.0068 0.0715
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0674 0.0427 0.3306
Toxoplasma gondii LsmAD domain-containing protein 0.0049 0.0018 0.0189
Plasmodium falciparum DNA gyrase subunit A 0.0674 0.0427 0.3306
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.021
Schistosoma mansoni cpg binding protein 0.0059 0.0024 0.0254
Plasmodium vivax SET domain protein, putative 0.0068 0.003 0.0231
Brugia malayi cathepsin F-like cysteine proteinase 0.0028 0.0004 0.0042
Brugia malayi Cathepsin L-like precursor 0.0085 0.0042 0.0436
Entamoeba histolytica cysteine protease, putative 0.0044 0.0015 0.0151
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.019 0.2002
Plasmodium vivax vivapain-2 0.0085 0.0042 0.032
Trypanosoma brucei Heat shock protein 83, putative 0.02 0.0116 0.088
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0052 0.002 0.002
Trypanosoma brucei heat shock protein, putative 0.02 0.0116 0.088
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0018 0.0018
Toxoplasma gondii histone lysine methyltransferase SET1 0.0116 0.0062 0.0648
Toxoplasma gondii DNA topoisomerase family protein 0.0157 0.0089 0.0932
Schistosoma mansoni cpg binding protein 0.0064 0.0028 0.0291
Loa Loa (eye worm) hypothetical protein 0.0102 0.0052 0.0552
Chlamydia trachomatis DNA gyrase subunit B 0.1994 0.129 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.0021 0.022
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.012 0.0064 0.005
Echinococcus multilocularis musashi 0.0113 0.006 0.0627
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0028 0.0004 0.0045
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0009 0.0091
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0003 0.0034
Schistosoma mansoni cathepsin F (C01 family) 0.0085 0.0042 0.0439
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0002 0.0022
Entamoeba histolytica DNA topoisomerase III, putative 0.0157 0.0089 0.0932
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0034 0.0353
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.1119 0.0718 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0014 0.015
Leishmania major heat shock protein 83-1 0.02 0.0116 0.088
Loa Loa (eye worm) hypothetical protein 0.0043 0.0014 0.015
Echinococcus granulosus dnaJ subfamily B 0.0834 0.0531 0.5607
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.012 0.0064 0.0485
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0028 0.0004 0.0042
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0014 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0021 0.0218
Mycobacterium tuberculosis Integral membrane indolylacetylinositol arabinosyltransferase EmbC (arabinosylindolylacetylinositol synthase) 1.531 1 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0014 0.015
Echinococcus granulosus lysosomal alpha glucosidase 0.0159 0.009 0.0945
Mycobacterium leprae Probable DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0211 0.0124 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0042 0.0436
Schistosoma mansoni lamin 0.0113 0.006 0.0629
Brugia malayi Cathepsin L-like precursor 0.0085 0.0042 0.0436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0023 0.0241
Brugia malayi PHD-finger family protein 0.003 0.0005 0.0051
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0046 0.049
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0002 0.0022
Loa Loa (eye worm) hypothetical protein 0.0069 0.0031 0.0325
Schistosoma mansoni microtubule-associated protein tau 0.1404 0.0904 0.9546
Schistosoma mansoni zinc finger protein 0.0024 0.0001 0.0015
Trypanosoma cruzi major cysteine proteinase, putative 0.0255 0.0153 0.1155
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.1313 0.0844 0.6394
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0031 0.0031
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0041 0.0013 0.0157
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.0021 0.0237
Trypanosoma brucei DNA topoisomerase II beta, putative 0.1313 0.0844 0.6394
Loa Loa (eye worm) cysteine protease 0.0085 0.0042 0.0439
Plasmodium falciparum heat shock protein 90, putative 0.0041 0.0013 0.0096
Trypanosoma cruzi cruzipain precursor, putative 0.0028 0.0004 0.003
Leishmania major heat shock protein 83-1 0.02 0.0116 0.088
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.012 0.0064 0.0064
Echinococcus multilocularis heat shock protein 0.02 0.0116 0.1227
Leishmania major cathepsin L-like protease 0.0085 0.0042 0.0313
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0674 0.0427 0.3306
Onchocerca volvulus 0.0085 0.0042 0.0561
Brugia malayi Cathepsin L-like precursor 0.0057 0.0023 0.0241
Leishmania major heat shock protein 83-1 0.02 0.0116 0.088
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.021
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.012 0.0064 0.0496
Trichomonas vaginalis heat shock protein, putative 0.008 0.0038 0.0398
Echinococcus multilocularis chromobox protein 1 0.0073 0.0034 0.0353
Plasmodium vivax endoplasmin, putative 0.02 0.0116 0.0901
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0014 0.0014
Schistosoma mansoni BC026374 protein (S09 family) 0.0069 0.0031 0.0325
Loa Loa (eye worm) hypothetical protein 0.0113 0.006 0.0629
Trypanosoma cruzi DNA topoisomerase III, putative 0.0157 0.0089 0.0668
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.2041 0.1321 1
Schistosoma mansoni hypothetical protein 0.0032 0.0007 0.0072
Leishmania major heat shock protein 83-1 0.02 0.0116 0.088
Loa Loa (eye worm) heat shock protein 90 0.02 0.0116 0.123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0042 0.0436
Trypanosoma cruzi cysteine peptidase, putative 0.0325 0.0198 0.1499
Plasmodium falciparum basic transcription factor 3b, putative 0.0037 0.001 0.0074
Plasmodium vivax acyl-CoA synthetase, putative 0.0052 0.002 0.0153
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0142 0.0079 0.0831
Leishmania major hypothetical protein, conserved 0.012 0.0064 0.0485
Schistosoma mansoni chromobox protein 0.0073 0.0034 0.0356
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.019 0.2002
Loa Loa (eye worm) transcription factor SMAD2 0.0126 0.0068 0.0717
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0069 0.0031 0.0325
Brugia malayi AMP-binding enzyme family protein 0.007 0.0031 0.033
Trichomonas vaginalis DNA topoisomerase II, putative 0.147 0.0947 1
Trichomonas vaginalis heat shock protein, putative 0.0041 0.0013 0.0131
Trypanosoma cruzi cysteine peptidase, putative 0.0085 0.0042 0.0313
Brugia malayi DNA topoisomerase II, alpha isozyme 0.147 0.0947 1
Onchocerca volvulus 0.0043 0.0014 0.018
Leishmania major heat shock protein 83-1 0.02 0.0116 0.088
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0085 0.0042 0.0436
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0015 0.0186
Brugia malayi Heterochromatin protein 1 0.0073 0.0034 0.0353
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.012 0.1261
Echinococcus granulosus cathepsin L cysteine proteinase 0.0085 0.0042 0.0436
Plasmodium falciparum heat shock protein 90 0.02 0.0116 0.0901
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0009 0.0091
Mycobacterium ulcerans two component sensor kinase MprB 0.012 0.0064 0.0064
Echinococcus multilocularis cysteine protease 0.0085 0.0042 0.0436
Entamoeba histolytica cysteine proteinase 2 0.0044 0.0015 0.0151
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0157 0.0089 0.0668
Onchocerca volvulus Cathepsin L homolog 0.0085 0.0042 0.0561
Trypanosoma cruzi cysteine proteinase, putative 0.0044 0.0015 0.0108
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0052 0.002 0.002
Echinococcus multilocularis para nitrobenzyl esterase 0.0069 0.0031 0.0322
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0157 0.0089 0.0934
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.0034 0.0356
Leishmania major cathepsin L-like protease 0.0085 0.0042 0.0313
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0014 0.0148
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0042 0.0436
Mycobacterium ulcerans integral membrane indolylacetylinositol arabinosyltransferase EmbA 1.531 1 1
Trypanosoma cruzi cysteine proteinase, putative 0.0044 0.0015 0.0108
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.003 0.0318
Mycobacterium ulcerans acyl-CoA synthetase 0.007 0.0031 0.0031
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0 0.0001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0007 0.0069
Plasmodium vivax hypothetical protein, conserved 0.012 0.0064 0.0496
Onchocerca volvulus 0.0069 0.0031 0.041
Echinococcus granulosus cpg binding protein 0.0064 0.0028 0.0289
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0014 0.0148
Loa Loa (eye worm) hypothetical protein 0.0052 0.002 0.0212
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0003 0.0034
Onchocerca volvulus 0.0157 0.0089 0.1216
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0014 0.0148
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0031 0.033
Brugia malayi Cathepsin L-like precursor 0.0085 0.0042 0.0436
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.012 0.1261
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.012 0.0064 0.0676
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0014 0.0014
Plasmodium vivax vivapain-2 0.0085 0.0042 0.032
Leishmania major heat shock protein 83-1 0.02 0.0116 0.088
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0031 0.0327
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0011 0.0108
Schistosoma mansoni cathepsin s 0.0028 0.0004 0.0045
Echinococcus multilocularis acetylcholinesterase 0.0407 0.0252 0.2657
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0 0.0001
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0018 0.0139
Mycobacterium ulcerans fatty-acid-CoA ligase 0.007 0.0031 0.0031
Brugia malayi hypothetical protein 0.0024 0.0001 0.0012
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.012 0.0064 0.0064
Loa Loa (eye worm) carboxylesterase 0.0407 0.0252 0.2659
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0031 0.0327
Schistosoma mansoni glutaminase 0.032 0.0195 0.2058
Loa Loa (eye worm) carboxylesterase 0.0069 0.0031 0.0325
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0113 0.006 0.0629
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0024 0.0254
Onchocerca volvulus 0.0085 0.0042 0.0561
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0015 0.0153
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0069 0.0031 0.0031
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0034 0.0353
Entamoeba histolytica cysteine protease, putative 0.0044 0.0015 0.0151
Trypanosoma cruzi cysteine peptidase, putative 0.0325 0.0198 0.1499
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0031 0.033
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0018 0.0018
Leishmania major heat shock protein 83-1 0.02 0.0116 0.088
Plasmodium falciparum DNA topoisomerase 2 0.147 0.0947 0.7339
Brugia malayi beta-lactamase 0.0043 0.0014 0.0148
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.1994 0.129 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.0052 0.0552
Entamoeba histolytica cysteine proteinase, putative 0.0044 0.0015 0.0151
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0021 0.0218
Loa Loa (eye worm) ICD-1 protein 0.0037 0.001 0.0104
Schistosoma mansoni heat shock protein 0.02 0.0116 0.123
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0014 0.0014
Leishmania major mitochondrial DNA topoisomerase II 0.2041 0.1321 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0 0.0003
Echinococcus granulosus endoplasmin 0.008 0.0038 0.0398
Plasmodium falciparum DNA topoisomerase 3, putative 0.0157 0.0089 0.0684
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0013 0.0158
Mycobacterium tuberculosis Conserved protein 0.012 0.0064 0.0064
Mycobacterium leprae Probable integral membrane indolylacetylinositol arabinosyltransferase EmbC (arabinosylindolylacetylinositol synthase) 1.531 1 1
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.012 0.0064 0.0676
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0009 0.0091
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0085 0.0042 0.0436
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.007 0.0031 0.0031
Trypanosoma cruzi heat shock protein 85, putative 0.02 0.0116 0.088
Chlamydia trachomatis DNA gyrase subunit B 0.1423 0.0917 0.706
Mycobacterium tuberculosis Conserved protein 0.0043 0.0014 0.0014
Echinococcus granulosus chromobox protein 1 0.0073 0.0034 0.0353
Schistosoma mansoni hypothetical protein 0.0032 0.0007 0.0072
Loa Loa (eye worm) intermediate filament protein 0.0113 0.006 0.0629
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0031 0.0327
Schistosoma mansoni cellular tumor antigen P53 0.006 0.0025 0.0263
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.1412 0.0909 0.9601
Echinococcus multilocularis acetylcholinesterase 0.0407 0.0252 0.2657
Trypanosoma cruzi heat shock protein 85, putative 0.02 0.0116 0.088
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0068 0.003 0.0315
Echinococcus multilocularis transcription factor btf3 0.0037 0.001 0.0101
Echinococcus multilocularis tumor protein p63 0.0408 0.0253 0.2666
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.012 0.0064 0.0064
Treponema pallidum DNA topoisomerase I (topA) 0.0157 0.0089 0.0684
Mycobacterium tuberculosis Conserved protein 0.0043 0.0014 0.0014
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0085 0.0042 0.032
Echinococcus granulosus neuropeptide receptor A26 0.0489 0.0305 0.3223
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.008 0.0038 0.0292
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0044 0.0015 0.0153
Entamoeba histolytica cysteine protease, putative 0.0044 0.0015 0.0151
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.007 0.0031 0.0017
Loa Loa (eye worm) hypothetical protein 0.0024 0.0001 0.0015
Leishmania major cathepsin L-like protease 0.0325 0.0198 0.1499
Schistosoma mansoni hypothetical protein 0.0696 0.0441 0.4656
Brugia malayi Cathepsin L-like precursor 0.0085 0.0042 0.0436
Loa Loa (eye worm) hypothetical protein 0.0043 0.0014 0.0146
Brugia malayi Endoplasmin precursor 0.02 0.0116 0.1227
Trypanosoma brucei heat shock protein, putative 0.02 0.0116 0.088

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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