Detailed information for compound 705130

Basic information

Technical information
  • TDR Targets ID: 705130
  • Name: N'-(2-dimethylaminoethyl)-N-(2-thiophen-2-yl- 2-thiophen-2-ylsulfonylethyl)oxamide
  • MW: 415.551 | Formula: C16H21N3O4S3
  • H donors: 2 H acceptors: 4 LogP: 1.48 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(CCNC(=O)C(=O)NCC(S(=O)(=O)c1cccs1)c1cccs1)C
  • InChi: 1S/C16H21N3O4S3/c1-19(2)8-7-17-15(20)16(21)18-11-13(12-5-3-9-24-12)26(22,23)14-6-4-10-25-14/h3-6,9-10,13H,7-8,11H2,1-2H3,(H,17,20)(H,18,21)
  • InChiKey: PCIWWXYDFVOYHU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N'-(2-dimethylaminoethyl)-N-[2-(2-thienyl)-2-(2-thienylsulfonyl)ethyl]oxamide
  • N'-(2-dimethylaminoethyl)-N-(2-thiophen-2-yl-2-thiophen-2-ylsulfonyl-ethyl)ethanediamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0012 0.0031 0.0025
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0157 0.0157
Entamoeba histolytica short chain dehydrogenase family protein 0.0012 0.0031 0.0025
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0709 0.0709
Loa Loa (eye worm) hypothetical protein 0.0308 0.4239 0.4552
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0212 0.1228
Echinococcus multilocularis transient receptor potential cation channel 0.0012 0.0031 0.0031
Schistosoma mansoni rab6-interacting 0.002 0.015 0.015
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0031 0.0031
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0157 0.0168
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0126 0.1653 1
Echinococcus granulosus Chromo domain 0.0012 0.0027 0.0027
Brugia malayi Protein cec-1. 0.0012 0.0027 0.0029
Mycobacterium ulcerans hypothetical protein 0.0025 0.022 0.1278
Giardia lamblia PHD finger protein 15 0.003 0.0288 0.2116
Leishmania major protein tyrosine phosphatase-likie protein 0.0022 0.0178 0.0499
Loa Loa (eye worm) thrombospondin type 1 domain-containing protein 0.0666 0.9312 1
Loa Loa (eye worm) hypothetical protein 0.0155 0.2055 0.2207
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0157 0.0168
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0477 0.0659
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0403 0.2907
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0092 0.0098
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.0027 0.0029
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0011 0.001 0.0011
Brugia malayi chromobox protein homolog 3 0.004 0.0434 0.0466
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0032 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0157 0.0168
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0157 0.0157
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.015 0.015
Leishmania major endonuclease G, putative 0.0185 0.249 0.8324
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Trichomonas vaginalis set domain proteins, putative 0.0493 0.6855 1
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.0031 0.0126
Onchocerca volvulus 0.0021 0.0157 0.0168
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0012 0.0031 0.0025
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Schistosoma mansoni carbonyl reductase 0.0012 0.0031 0.0031
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0012 0.0027 0.0027
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0212 0.0612
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.022 0.064
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0031 0.0031
Schistosoma mansoni kinase 0.005 0.0565 0.0565
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0477 0.0513
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0022 0.0175 0.0175
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Echinococcus multilocularis gpi ethanolamine phosphate transferase 1 0.0049 0.0549 0.0549
Mycobacterium ulcerans hypothetical protein 0.0025 0.0212 0.1228
Onchocerca volvulus Ectonucleotide pyrophosphatase\/phosphodiesterase family member 6 homolog 0.0049 0.0549 0.0589
Echinococcus multilocularis transferase 0.0049 0.0549 0.0549
Echinococcus granulosus Protein patched homolog 1 0.0044 0.0487 0.0487
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0028 0.0257 0.0257
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0018
Onchocerca volvulus 0.0074 0.0909 0.0976
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0012 0.0031 0.0033
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0212 0.3481
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Schistosoma mansoni chromobox protein 0.0012 0.0027 0.0027
Brugia malayi Trypsin family protein 0.0011 0.001 0.0011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0741 0.0741
Loa Loa (eye worm) hypothetical protein 0.0155 0.2055 0.2207
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0157 0.0168
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0017 0.0017
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0067 0.0817 0.0877
Onchocerca volvulus 0.0493 0.6855 0.7361
Schistosoma mansoni patched 1 0.0044 0.0487 0.0487
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Loa Loa (eye worm) hypothetical protein 0.026 0.355 0.3812
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0361 0.0387
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Schistosoma mansoni hypothetical protein 0.0043 0.0464 0.0464
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0022 0.0175 0.0188
Mycobacterium ulcerans dehydrogenase/reductase 0.0012 0.0031 0.0126
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0011
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0019 0.0132 0.0142
Brugia malayi Trypsin family protein 0.0011 0.001 0.0011
Echinococcus granulosus expressed conserved protein 0.0097 0.1232 0.1232
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Toxoplasma gondii oxidoreductase, putative 0.0012 0.0031 0.0013
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0108 0.0479
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0403 0.0403
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0288 0.1059
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Loa Loa (eye worm) hypothetical protein 0.0054 0.0628 0.0674
Schistosoma mansoni hypothetical protein 0.0016 0.0092 0.0092
Entamoeba histolytica phosphatidylinositol-glycan biosynthesis class O protein, putative 0.0049 0.0549 0.403
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0098 0.1248 0.4119
Loa Loa (eye worm) hypothetical protein 0.0021 0.0157 0.0168
Schistosoma mansoni hypothetical protein 0.0043 0.0464 0.0464
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0288 0.0288
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0098 0.1248 0.134
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0157 0.0168
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0547 0.0761
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0266 0.035
Echinococcus multilocularis Chromo domain 0.0012 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0021 0.0157 0.0168
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0403 0.0403
Loa Loa (eye worm) hypothetical protein 0.0049 0.0549 0.0589
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0012 0.0031 0.0033
Entamoeba histolytica hypothetical protein 0.0049 0.055 0.4044
Loa Loa (eye worm) hypothetical protein 0.002 0.015 0.0161
Plasmodium vivax hypothetical protein, conserved 0.003 0.0288 0.3653
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0031 0.0126
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0011 0.001 0.001
Echinococcus granulosus enteropeptidase 0.0011 0.001 0.001
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.0487 0.0523
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0023 0.0189 0.0203
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0108 0.0479
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0012 0.0031 0.0013
Brugia malayi nuclear receptor RXR 0.0011 0.0017 0.0018
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.0884 0.0949
Echinococcus multilocularis chromobox protein 2 0.0012 0.0027 0.0027
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Onchocerca volvulus 0.0012 0.0031 0.0033
Brugia malayi Pre-SET motif family protein 0.0062 0.0741 0.0796
Plasmodium vivax steroid dehydrogenase, putative 0.0012 0.0031 0.0045
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0212 0.0612
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0403 0.0403
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0744 0.0799
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0029
Loa Loa (eye worm) hypothetical protein 0.0018 0.0122 0.0131
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0157 0.0157
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0027 0.0027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0741 0.0741
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0434 0.0595
Echinococcus granulosus Chromobox protein 3 0.0012 0.0027 0.0027
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0456 0.0456
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Onchocerca volvulus GPI ethanolamine phosphate transferase 2 homolog 0.0049 0.0549 0.0589
Schistosoma mansoni retinal dehydrogenase 0.0012 0.0031 0.0031
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0157 0.0168
Schistosoma mansoni microtubule-associated protein tau 0.0714 1 1
Echinococcus granulosus WW domain containing oxidoreductase 0.0012 0.0031 0.0031
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0532 0.0571
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0025 0.022 0.0282
Echinococcus multilocularis microtubule associated protein 2 0.0714 1 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0288 0.031
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0012 0.0031 0.0031
Echinococcus multilocularis oxidoreductase 0.0012 0.0031 0.0031
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0308 0.4239 0.4239
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.026 0.355 0.355
Leishmania major tyrosine specific protein phosphatase, putative 0.0019 0.0132 0.0342
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.015 0.015
Trypanosoma brucei polo-like protein kinase 0.0098 0.1248 0.4119
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.0031 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0157 0.0168
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0403 0.0403
Echinococcus multilocularis chromobox protein 1 0.0072 0.0884 0.0884
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0067 0.0817 0.4846
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0012 0.0031 0.0126
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0157 0.0157
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0532 0.0532
Schistosoma mansoni carbonyl reductase 0.0012 0.0031 0.0031
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0532 0.0571
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.0487 0.0487
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0378 0.0378
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0012 0.0031 0.0031
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0049 0.055 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0099 0.1263 0.1263
Entamoeba histolytica serine/threonine protein kinase, putative 0.0098 0.1248 0.9439
Echinococcus granulosus muscleblind protein 0.0155 0.2055 0.2055
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1248 0.1788
Echinococcus multilocularis Endonuclease G 0.0185 0.249 0.249
Brugia malayi hypothetical protein 0.0012 0.0031 0.0033
Brugia malayi Dehydrogenases, short chain protein 30 0.0012 0.0031 0.0033
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1653 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.022 0.2986 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0403 0.0403
Echinococcus multilocularis Alkaline phosphatase, core domain 0.0049 0.0549 0.0549
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0029
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0011 0.001 0.001
Onchocerca volvulus 0.0032 0.031 0.0333
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Trypanosoma cruzi protein tyrosine phosphatase, putative 0.0022 0.0178 0.0499
Brugia malayi jmjC domain containing protein 0.0037 0.0378 0.0406
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0532 0.0532
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0028 0.0257 0.0257
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Echinococcus multilocularis Niemann Pick C1 protein 0.0147 0.1947 0.1947
Schistosoma mansoni protein tyrosine phosphatase prl 0.0022 0.0178 0.0178
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0123 0.0567
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Schistosoma mansoni chromobox protein 0.0072 0.0884 0.0884
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0157 0.0168
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0017 0.0018
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0403 0.1261
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0031 0.0005
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0013
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0212 0.1424
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0378 0.0406
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0011 0.001 0.001
Brugia malayi hypothetical protein 0.0049 0.0549 0.0589
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0157 0.0157
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0157 0.0168
Loa Loa (eye worm) doublecortin family protein 0.002 0.015 0.0161
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0403 0.055
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0012 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0029
Onchocerca volvulus Serine\/threonine kinase homolog 0.0098 0.1248 0.134
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0031 0.0031
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0011 0.001 0.001
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0012 0.0031 0.0013
Brugia malayi endonuclease G, mitochondrial precursor 0.0185 0.249 0.2674
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0288 0.0288
Onchocerca volvulus 0.0011 0.001 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0266 0.035
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0157 0.0157
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0403 0.0403
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0019 0.0132 0.0132
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Trypanosoma cruzi protein tyrosine phosphatase PRL 0.0022 0.0178 0.0499
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0157 0.0157
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0212 0.1228
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0157 0.0168
Brugia malayi CHD4 protein 0.0012 0.0027 0.0029
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0592 0.0636
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0011
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0031 0.0031
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0023 0.0189 0.0203
Onchocerca volvulus 0.0012 0.0027 0.0029
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0012 0.0031 0.0031
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0012 0.0031 0.0126
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.015 0.015
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.026 0.355 0.355
Brugia malayi Trypsin-like protease protein 5 0.0011 0.001 0.0011
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Loa Loa (eye worm) CHromoDomain protein family member 0.0012 0.0027 0.0029
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0157 0.0168
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0157 0.0168
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0741 0.0741
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0022 0.0175 0.0175
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0212 0.1228
Schistosoma mansoni coup transcription factor 0.0021 0.0157 0.0157
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0175 0.0175
Onchocerca volvulus 0.0012 0.0031 0.0033
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Brugia malayi Muscleblind-like protein 0.0155 0.2055 0.2207
Schistosoma mansoni carbonyl reductase 0.0012 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0011
Echinococcus multilocularis Chromobox protein 3 0.0012 0.0027 0.0027
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0403 0.1261
Echinococcus multilocularis chromobox protein 1 0.0072 0.0884 0.0884
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0378 0.0378
Echinococcus multilocularis RUN 0.002 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0101 0.1301 0.1397
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.1248 0.1248
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Trypanosoma cruzi endonuclease G, putative 0.0185 0.249 0.8324
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0018
Trypanosoma cruzi protein tyrosine phosphatase, putative 0.0022 0.0178 0.0499
Loa Loa (eye worm) hypothetical protein 0.0025 0.0212 0.0227
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0532 0.0532
Onchocerca volvulus 0.002 0.015 0.0161
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0029
Onchocerca volvulus 0.0019 0.0134 0.0144
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.022 0.1278
Brugia malayi hypothetical protein 0.0012 0.0027 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Plasmodium vivax SET domain protein, putative 0.0062 0.0741 1
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0067 0.0817 0.0817
Loa Loa (eye worm) hypothetical protein 0.0044 0.0487 0.0523
Brugia malayi hypothetical protein 0.002 0.015 0.0161
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.022 0.1278
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0646 0.0694
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0049 0.0549 0.0589
Onchocerca volvulus 0.0012 0.0031 0.0033
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0049 0.055 0.5
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Mycobacterium ulcerans hypothetical protein 0.0049 0.0549 0.3279
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0108 0.0479
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0012 0.0031 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0157 0.0168
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0157 0.0157
Mycobacterium leprae conserved hypothetical protein 0.0049 0.055 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0378 0.0378
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0157 0.0157
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0098 0.1248 0.1248
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0018 0.0114 0.0122
Brugia malayi Valyl-tRNA synthetase 0.0012 0.0027 0.0029
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0092 0.0092
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.015 0.015
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0028 0.0257 0.0257
Onchocerca volvulus 0.0012 0.0031 0.0033
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.0031 0.0031
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0049 0.0549 0.0549
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0012 0.0031 0.0005
Trypanosoma cruzi protein tyrosine phosphatase-like protein, putative 0.0022 0.0178 0.0499
Loa Loa (eye worm) hypothetical protein 0.0016 0.0092 0.0098
Mycobacterium ulcerans carveol-like dehydrogenase 0.0012 0.0031 0.0126
Trypanosoma cruzi endonuclease G, putative 0.0185 0.249 0.8324
Echinococcus multilocularis sortilin receptor 0.0015 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0035 0.0361 0.0387
Brugia malayi jmjC domain containing protein 0.0099 0.1263 0.1356
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0212 0.1228
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0019 0.0132 0.0132
Onchocerca volvulus 0.0011 0.001 0.0011
Echinococcus multilocularis gpi ethanolamine phosphate transferase 3 0.0049 0.0549 0.0549
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0052 0.0592 0.0636
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Brugia malayi Heterochromatin protein 1 0.0072 0.0884 0.0949
Onchocerca volvulus 0.0666 0.9312 1
Schistosoma mansoni hypothetical protein 0.002 0.015 0.015
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0011
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0011 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0157 0.0157
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0025 0.0211 0.0211
Onchocerca volvulus 0.0012 0.0031 0.0033
Echinococcus granulosus Endonuclease G 0.0185 0.249 0.249
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0308 0.4239 0.4552
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1248 0.1788
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.1248 0.4119
Brugia malayi ecdysteroid receptor 0.0021 0.0157 0.0168
Schistosoma mansoni hypothetical protein 0.0011 0.001 0.001
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Trypanosoma brucei phosphatase of regenerating liver-type phosphatase, putative 0.0022 0.0178 0.0499
Schistosoma mansoni lipoxygenase 0.002 0.015 0.015
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.0031 0.0031
Echinococcus multilocularis glycoprotein Antigen 5 0.0011 0.001 0.001
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0741 0.0741
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0288 0.1059
Giardia lamblia Phosphatidylinositol-glycan biosynthesis, class O protein 0.0049 0.0549 0.4255
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.0487 0.0487
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0031 0.0031
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0403 0.0433
Onchocerca volvulus 0.0012 0.0031 0.0033
Echinococcus multilocularis transmembrane protease serine 3 0.0011 0.001 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0212 0.1228
Loa Loa (eye worm) hypothetical protein 0.0019 0.0123 0.0132
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0031 0.0005
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Entamoeba histolytica phosphatidylinositol-glycan biosynthesis class O protein, putative 0.0049 0.0549 0.403
Entamoeba histolytica hypothetical protein, conserved 0.0012 0.0031 0.0025
Schistosoma mansoni hypothetical protein 0.0043 0.0464 0.0464
Plasmodium falciparum protein tyrosine phosphatase 0.0022 0.0178 0.288
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0012 0.0031 0.0031
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0031 0.0031
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0031 0.0031
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0308 0.4239 0.4239
Onchocerca volvulus 0.0012 0.0031 0.0033
Mycobacterium tuberculosis Conserved protein 0.0025 0.022 0.1166
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Echinococcus multilocularis protein dispatched 1 0.005 0.0575 0.0575
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0031 0.0126
Schistosoma mansoni hypothetical protein 0.0049 0.0549 0.0549
Echinococcus granulosus oxidoreductase 0.0012 0.0031 0.0031
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0049 0.0549 0.0549
Echinococcus multilocularis enteropeptidase 0.0011 0.001 0.001
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0012 0.0031 0.0033
Brugia malayi Doublecortin family protein 0.002 0.015 0.0161
Echinococcus granulosus hypothetical protein 0.0012 0.0031 0.0031
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0012 0.0031 0.0025
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1248 0.1788
Brugia malayi nuclear receptor NHR-88 0.0021 0.0157 0.0168
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0012 0.0031 0.0126
Plasmodium falciparum LCCL domain-containing protein 0.002 0.015 0.2336
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0212 0.1424
Onchocerca volvulus 0.0011 0.001 0.0011
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0092 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0135 0.0158
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0157 0.0157
Trypanosoma cruzi protein tyrosine phosphatase, putative 0.0022 0.0178 0.0499
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0012 0.0031 0.0033
Loa Loa (eye worm) hypothetical protein 0.0021 0.0157 0.0168
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.0031 0.0126
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0212 0.0612
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0092 0.0092
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0019 0.0132 0.0342
Loa Loa (eye worm) hypothetical protein 0.004 0.0434 0.0466
Mycobacterium ulcerans hypothetical protein 0.0025 0.022 0.1278
Loa Loa (eye worm) trypsin family protein 0.0011 0.001 0.0011
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0157 0.0157
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Onchocerca volvulus 0.0012 0.0031 0.0033
Echinococcus multilocularis protein tyrosine phosphatase PRL 0.0022 0.0178 0.0178
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0288 0.0288
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1248 0.1788
Trypanosoma cruzi protein tyrosine phosphatase-like protein, putative 0.0022 0.0178 0.0499
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0012 0.0031 0.0031
Echinococcus multilocularis retinol dehydrogenase 13 0.0012 0.0031 0.0031
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0532 0.0532
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Loa Loa (eye worm) hypothetical protein 0.0025 0.0212 0.0227
Echinococcus granulosus L aminoadipate semialdehyde 0.0173 0.2315 0.2315
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.1248 0.4119
Schistosoma mansoni rab6-interacting 0.002 0.015 0.015
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.015 0.015
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0123 0.0687
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.022 0.064
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0062 0.0741 0.0796
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Brugia malayi CHE-14 protein 0.0044 0.0487 0.0523
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0049 0.0549 0.0589
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0018
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0308 0.4239 0.4239
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0049 0.055 0.2123
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1653 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Echinococcus granulosus Niemann Pick C1 protein 0.0103 0.132 0.132
Schistosoma mansoni hypothetical protein 0.0049 0.0549 0.0549
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0012 0.0031 0.0033
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0012 0.0031 0.0031
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0067 0.0817 0.4912
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1248 0.1788
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0212 0.1424
Brugia malayi PHD-finger family protein 0.003 0.0288 0.031
Echinococcus multilocularis L aminoadipate semialdehyde 0.0173 0.2315 0.2315
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.0031 0.0126
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0157 0.0157
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0434 0.0595
Brugia malayi Pre-SET motif family protein 0.0433 0.6006 0.6449
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Echinococcus granulosus GPCR family 2 0.0016 0.0092 0.0092
Brugia malayi hypothetical protein 0.0012 0.0031 0.0033
Echinococcus multilocularis protein patched 0.0044 0.0487 0.0487
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Loa Loa (eye worm) hypothetical protein 0.0038 0.0403 0.0433
Echinococcus granulosus steroid dehydrogenase 0.0012 0.0031 0.0031
Schistosoma mansoni lipoxygenase 0.0057 0.0671 0.0671
Onchocerca volvulus 0.0173 0.2315 0.2486
Onchocerca volvulus 0.0011 0.001 0.0011
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.0031 0.0031
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0012 0.0031 0.0033
Onchocerca volvulus 0.0012 0.0031 0.0033
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Onchocerca volvulus Ectonucleotide pyrophosphatase\/phosphodiesterase family member 7 homolog 0.0049 0.0549 0.0589
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0288 0.031
Echinococcus granulosus ectonucleotide 0.026 0.355 0.355
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0157 0.0168
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0433 0.6006 0.6449
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0157 0.0157
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0403 0.0403
Onchocerca volvulus GPI ethanolamine phosphate transferase 3 homolog 0.0049 0.0549 0.0589
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0173 0.2315 0.2315
Giardia lamblia Kinase, PLK 0.0098 0.1248 1
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0157 0.0168
Toxoplasma gondii DNA/RNA non-specific endonuclease 0.0185 0.249 1
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0103 0.132 1
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0098 0.1248 0.1248
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0049 0.0549 0.0589
Schistosoma mansoni hypothetical protein 0.0016 0.0092 0.0092
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0592 0.0636
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0017 0.0017
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0012 0.0031 0.0062
Loa Loa (eye worm) hypothetical protein 0.0021 0.0157 0.0168
Echinococcus multilocularis muscleblind protein 0.0155 0.2055 0.2055
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0884 0.1254
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0308 0.4239 0.4239
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Entamoeba histolytica hypothetical protein 0.0012 0.0031 0.0025
Trypanosoma brucei GPI ethanolamine phosphate transferase 3, putative 0.0049 0.0549 0.1753
Onchocerca volvulus 0.0025 0.0212 0.0227
Echinococcus granulosus hypothetical protein 0.0012 0.0031 0.0031
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.1653 0.1653
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0487 0.0673
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0027 0.0027
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0456 0.0456
Brugia malayi hypothetical protein 0.0011 0.0017 0.0018
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0028 0.0257 0.0257
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0067 0.0817 0.266
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Brugia malayi oxidoreductase 0.0012 0.0031 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Onchocerca volvulus 0.002 0.015 0.0161
Toxoplasma gondii oxidoreductase, putative 0.0012 0.0031 0.0013
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0157 0.0168
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1653 1
Echinococcus granulosus chromobox protein 2 0.0012 0.0027 0.0027
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0012 0.0031 0.0025
Schistosoma mansoni endonuclease related 0.0185 0.249 0.249
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0012 0.0031 0.0062
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0011 0.001 0.001
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0308 0.4239 0.4552
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.1301 0.1301
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0547 0.0761
Echinococcus multilocularis Niemann Pick C1 protein 0.0103 0.132 0.132
Loa Loa (eye worm) hypothetical protein 0.0173 0.2315 0.2486
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0157 0.0157
Echinococcus multilocularis conserved hypothetical protein 0.0012 0.0031 0.0031
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0012 0.0031 0.0126
Loa Loa (eye worm) hypothetical protein 0.0103 0.132 0.1418
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0157 0.0168
Loa Loa (eye worm) hypothetical protein 0.0025 0.0212 0.0227
Leishmania major ethanolamine phosphotransferase, putative 0.0049 0.0549 0.1753
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0019 0.0123 0.0132
Loa Loa (eye worm) hypothetical protein 0.0049 0.0549 0.0589
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0741 0.2899
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0012 0.0031 0.0031
Echinococcus granulosus Mastin 0.0011 0.001 0.001
Echinococcus multilocularis GPCR, family 2 0.0016 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0018
Schistosoma mansoni loxhd1 0.002 0.015 0.015
Onchocerca volvulus Alhambra homolog 0.003 0.0288 0.031
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0.0027 0.0029
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0157 0.0157
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0013
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0067 0.0817 0.4912
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0741 0.0741
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0157 0.0168
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0017 0.0017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0108 0.0479
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0049 0.0549 0.0549
Plasmodium falciparum phd finger protein, putative 0.003 0.0288 0.4988
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0012 0.0032 0.0032
Loa Loa (eye worm) type I phosphodiesterase/nucleotide pyrophosphatase 0.0049 0.0549 0.0589
Onchocerca volvulus 0.0019 0.0132 0.0142
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0011 0.001 0.001
Echinococcus multilocularis Mastin 0.0011 0.001 0.001
Brugia malayi Niemann-Pick C1 protein precursor 0.0103 0.132 0.1418
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.0031 0.0031
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.0031 0.0031
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0126 0.1653 0.1653
Echinococcus granulosus transmembrane protease serine 3 0.0011 0.001 0.001
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0157 0.0168
Brugia malayi dehydrogenases, short chain protein 9 0.0012 0.0031 0.0033
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0011 0.001 0.001
Plasmodium falciparum steroid dehydrogenase, putative 0.0012 0.0031 0.0062
Onchocerca volvulus 0.0012 0.0027 0.0029
Trypanosoma brucei endonuclease G, putative 0.0185 0.249 0.8324
Toxoplasma gondii carbonyl reductase 1, putative 0.0012 0.0031 0.0013
Echinococcus granulosus Niemann Pick C1 protein 0.0147 0.1947 0.1947
Loa Loa (eye worm) hypothetical protein 0.0019 0.0123 0.0132
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0185 0.249 0.8324
Echinococcus multilocularis expressed conserved protein 0.0097 0.1232 0.1232
Loa Loa (eye worm) dehydrogenase 0.0012 0.0031 0.0033
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0049 0.055 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0157 0.0168
Onchocerca volvulus 0.0012 0.0031 0.0033
Echinococcus multilocularis peregrin 0.003 0.0288 0.0288
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0049 0.055 0.329
Brugia malayi SET domain containing protein 0.0014 0.006 0.0064
Mycobacterium ulcerans oxidoreductase 0.0012 0.0031 0.0126
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0123 0.1334
Trypanosoma cruzi protein tyrosine phosphatase-like protein, putative 0.0022 0.0178 0.0499
Brugia malayi hypothetical protein 0.0011 0.0017 0.0018
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0049 0.055 0.7325
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0212 0.0227
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0092 0.0098
Toxoplasma gondii aldehyde dehydrogenase 0.0126 0.1653 0.66
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0012 0.0031 0.0013
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0049 0.055 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.031 0.0333
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Mycobacterium ulcerans short-chain type oxidoreductase 0.0012 0.0031 0.0126
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0185 0.249 0.8324
Leishmania major hypothetical protein, conserved 0.022 0.2986 1
Mycobacterium ulcerans dehydrogenase 0.0012 0.0031 0.0126
Plasmodium falciparum GPI ethanolamine phosphate transferase 3, putative 0.0049 0.0549 0.9966
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0031 0.0005
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0099 0.1263 0.1263
Loa Loa (eye worm) hypothetical protein 0.0308 0.4239 0.4552
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0049 0.055 0.329
Echinococcus granulosus citrate lyase subunit beta protein 0.0025 0.022 0.022
Brugia malayi hypothetical protein 0.002 0.015 0.0161
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0403 0.3061
Onchocerca volvulus 0.0012 0.0031 0.0033
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0031 0.0045
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0126 0.1653 0.5489
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0477 0.0659
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0434 0.0466
Trypanosoma cruzi protein tyrosine phosphatase-like protein, putative 0.0022 0.0178 0.0499
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1248 0.1788
Brugia malayi Retinol dehydrogenase 12 0.0012 0.0031 0.0033
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0532 0.0532
Schistosoma mansoni protein tyrosine phosphatase prl 0.0022 0.0178 0.0178
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0157 0.0157
Echinococcus granulosus chromobox protein 1 0.0072 0.0884 0.0884
Onchocerca volvulus Sepiapterin reductase homolog 0.0012 0.0031 0.0033
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Schistosoma mansoni hypothetical protein 0.003 0.0288 0.0288
Schistosoma mansoni hypothetical protein 0.0049 0.0549 0.0549
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0012 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0016 0.0092 0.0092
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0157 0.0168
Echinococcus multilocularis citrate lyase subunit beta protein 0.0025 0.022 0.022
Echinococcus granulosus glycoprotein Antigen 5 0.0011 0.001 0.001
Brugia malayi serine/threonine-protein kinase plk-2 0.0098 0.1248 0.134
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.1653 0.1653
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0157 0.0168
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0013
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0157 0.0157
Brugia malayi hypothetical protein 0.0049 0.0549 0.0589
Trypanosoma brucei endonuclease G, putative 0.0185 0.249 0.8324
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0741 0.0741
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0212 0.1228
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0212 0.0227
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Leishmania major phosphopantetheinyl transferase-like protein 0.0049 0.055 0.1759
Brugia malayi Bromodomain containing protein 0.003 0.0288 0.031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0123 0.0132
Trichomonas vaginalis steroid dehydrogenase, putative 0.0012 0.0031 0.0005
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0022 0.0178 0.1165
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0012 0.0031 0.0025
Schistosoma mansoni hypothetical protein 0.0666 0.9312 0.9312
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0212 0.3481
Entamoeba histolytica short chain dehydrogenase family protein 0.0012 0.0031 0.0025
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0031 0.0126
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0157 0.0157
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1248 0.1788
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0212 0.1115
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0031 0.0005
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0403 0.1261
Loa Loa (eye worm) hypothetical protein 0.0021 0.0157 0.0168
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0011 0.001 0.001
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0057 0.0671 0.0671
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0157 0.0157
Mycobacterium ulcerans oxidoreductase 0.0012 0.0031 0.0126
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0101 0.1301 0.1397
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0157 0.0168
Trypanosoma brucei hypothetical protein, conserved 0.0049 0.055 0.1759
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0012 0.0027 0.0027
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0029
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0157 0.0157
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0157 0.0168
Trypanosoma brucei endonuclease G, putative 0.0185 0.249 0.8324
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0021 0.0157 0.0168
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0212 0.0227
Echinococcus granulosus protein tyrosine phosphatase PRL 0.0022 0.0178 0.0178
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.015 0.1711
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0057 0.0671 0.0671
Schistosoma mansoni chromobox protein 0.0012 0.0027 0.0027
Plasmodium vivax protein tyrosine phosphatase, putative 0.0022 0.0178 0.211
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0403 0.0403
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0157 0.0168
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0031 0.0126
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0157 0.0168
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0092 0.0092
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0157 0.0157
Echinococcus granulosus transferase 0.0049 0.0549 0.0549
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0031 0.0005
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Leishmania major protein tyrosine phosphatase-like protein 0.0022 0.0178 0.0499
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0031 0.0005
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0017 0.0017
Onchocerca volvulus 0.0091 0.1151 0.1236
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0031 0.0005
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0104 0.1343 0.1343
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0031 0.0005
Echinococcus granulosus peregrin 0.003 0.0288 0.0288
Brugia malayi Trypsin family protein 0.0011 0.001 0.0011
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0074 0.0909 0.0909
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0013
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0012 0.0031 0.0005
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0019 0.0132 0.0132
Echinococcus granulosus gpi ethanolamine phosphate transferase 3 0.0049 0.0549 0.0549
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Brugia malayi Trypsin family protein 0.0101 0.1301 0.1397
Onchocerca volvulus 0.0011 0.001 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0403 0.055
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0157 0.0157
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Mycobacterium leprae hypothetical protein 0.0049 0.0549 0.9965
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0018
Loa Loa (eye worm) hypothetical protein 0.0052 0.0594 0.0638
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.022 0.064
Brugia malayi dehydrogenases, short chain protein 2 0.0012 0.0031 0.0033
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0123 0.1821
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0378 0.0378
Trypanosoma cruzi hypothetical protein, conserved 0.022 0.2986 1
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0049 0.0549 0.0549
Echinococcus multilocularis muscleblind protein 1 0.0155 0.2055 0.2055
Echinococcus granulosus RUN 0.002 0.015 0.015
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0013
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.1301 0.1301
Brugia malayi M-phase phosphoprotein, mpp8 0.0012 0.0027 0.0029
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.022 0.1278
Schistosoma mansoni hypothetical protein 0.0016 0.0092 0.0092
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.022 0.1166
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0157 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0403 0.055
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0067 0.0817 0.0817
Onchocerca volvulus 0.0012 0.0031 0.0033
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Brugia malayi Thrombospondin type 1 domain containing protein 0.0666 0.9312 1
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Schistosoma mansoni hypothetical protein 0.0012 0.0027 0.0027
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0212 0.1115
Loa Loa (eye worm) hypothetical protein 0.0049 0.0549 0.0589
Schistosoma mansoni jumonji domain containing protein 0.0079 0.0975 0.0975
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0012 0.0031 0.0031
Trypanosoma brucei hypothetical protein, conserved 0.022 0.2986 1
Schistosoma mansoni hypothetical protein 0.0035 0.0361 0.0361
Loa Loa (eye worm) hypothetical protein 0.002 0.015 0.0161
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0212 0.1228
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Schistosoma mansoni hypothetical protein 0.0011 0.001 0.001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0532 0.0532
Schistosoma mansoni chromobox protein 0.0072 0.0884 0.0884
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0049 0.055 0.2123
Schistosoma mansoni polycystin 1-related 0.002 0.015 0.015
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0012 0.0031 0.0031
Onchocerca volvulus 0.0308 0.4239 0.4552
Onchocerca volvulus 0.0101 0.1301 0.1397
Brugia malayi steroid hormone receptor 0.0021 0.0157 0.0168
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0126 0.1653 0.1653
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0027 0.0027
Onchocerca volvulus 0.0308 0.4239 0.4552
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0017 0.0018
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0173 0.2315 0.2486
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0028 0.0257 0.0257
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.015 0.015
Brugia malayi Dehydrogenases, short chain protein 2 0.0012 0.0031 0.0033
Brugia malayi hypothetical protein 0.0011 0.001 0.0011
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0157 0.0157
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0012 0.0031 0.0031
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0027 0.0027
Loa Loa (eye worm) dehydrogenase 0.0012 0.0031 0.0033
Schistosoma mansoni hypothetical protein 0.0049 0.0549 0.0549
Leishmania major DNA/RNA non-specific endonuclease-like protein 0.0185 0.249 0.8324
Echinococcus granulosus chromobox protein 1 0.0072 0.0884 0.0884
Entamoeba histolytica hypothetical protein, conserved 0.0012 0.0031 0.0025
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0532 0.0532
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0092 0.0092
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0403 0.1261
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0175 0.0175
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0157 0.0168
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0019 0.0132 0.0342
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Toxoplasma gondii hypothetical protein 0.0019 0.0135 0.0438
Brugia malayi nuclear hormone receptor 0.0021 0.0157 0.0168
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0067 0.0817 0.0817
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0049 0.055 0.3204
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0592 0.0636
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0011 0.001 0.001
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0017 0.0018
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0157 0.0168
Loa Loa (eye worm) hypothetical protein 0.0019 0.0123 0.0132
Brugia malayi AEL166Cp 0.0049 0.0549 0.0589
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0884 0.1254
Loa Loa (eye worm) helicase 0.0012 0.0027 0.0029
Loa Loa (eye worm) hypothetical protein 0.0021 0.0157 0.0168
Echinococcus multilocularis ectonucleotide 0.026 0.355 0.355
Schistosoma mansoni hypothetical protein 0.0043 0.0464 0.0464
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0157 0.0157

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.