Detailed information for compound 705130

Basic information

Technical information
  • TDR Targets ID: 705130
  • Name: N'-(2-dimethylaminoethyl)-N-(2-thiophen-2-yl- 2-thiophen-2-ylsulfonylethyl)oxamide
  • MW: 415.551 | Formula: C16H21N3O4S3
  • H donors: 2 H acceptors: 4 LogP: 1.48 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(CCNC(=O)C(=O)NCC(S(=O)(=O)c1cccs1)c1cccs1)C
  • InChi: 1S/C16H21N3O4S3/c1-19(2)8-7-17-15(20)16(21)18-11-13(12-5-3-9-24-12)26(22,23)14-6-4-10-25-14/h3-6,9-10,13H,7-8,11H2,1-2H3,(H,17,20)(H,18,21)
  • InChiKey: PCIWWXYDFVOYHU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N'-(2-dimethylaminoethyl)-N-[2-(2-thienyl)-2-(2-thienylsulfonyl)ethyl]oxamide
  • N'-(2-dimethylaminoethyl)-N-(2-thiophen-2-yl-2-thiophen-2-ylsulfonyl-ethyl)ethanediamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0403 0.0403
Onchocerca volvulus 0.0012 0.0031 0.0033
Loa Loa (eye worm) dehydrogenase 0.0012 0.0031 0.0033
Trypanosoma cruzi endonuclease G, putative 0.0185 0.249 0.8324
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Echinococcus multilocularis ectonucleotide 0.026 0.355 0.355
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0157 0.0168
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.015 0.015
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0709 0.0709
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0157 0.0157
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0212 0.0227
Echinococcus multilocularis peregrin 0.003 0.0288 0.0288
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0212 0.0612
Echinococcus multilocularis muscleblind protein 0.0155 0.2055 0.2055
Trichomonas vaginalis set domain proteins, putative 0.0493 0.6855 1
Onchocerca volvulus 0.0012 0.0031 0.0033
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0031 0.0126
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.0487 0.0487
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0012 0.0031 0.0031
Echinococcus granulosus Niemann Pick C1 protein 0.0147 0.1947 0.1947
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0403 0.0433
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0157 0.0157
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1248 0.1788
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0029
Brugia malayi Valyl-tRNA synthetase 0.0012 0.0027 0.0029
Trypanosoma cruzi endonuclease G, putative 0.0185 0.249 0.8324
Brugia malayi SET domain containing protein 0.0014 0.006 0.0064
Onchocerca volvulus 0.0011 0.001 0.0011
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0098 0.1248 0.1248
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Echinococcus multilocularis Chromobox protein 3 0.0012 0.0027 0.0027
Onchocerca volvulus 0.0011 0.001 0.0011
Plasmodium vivax hypothetical protein, conserved 0.003 0.0288 0.3653
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0212 0.1228
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0403 0.0403
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0012 0.0031 0.0062
Echinococcus granulosus Chromobox protein 3 0.0012 0.0027 0.0027
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.1653 0.1653
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Brugia malayi CHE-14 protein 0.0044 0.0487 0.0523
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0884 0.1254
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Trypanosoma cruzi protein tyrosine phosphatase-like protein, putative 0.0022 0.0178 0.0499
Brugia malayi CHD4 protein 0.0012 0.0027 0.0029
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0012 0.0031 0.0031
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0012 0.0031 0.0033
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0378 0.0378
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.015 0.015
Schistosoma mansoni hypothetical protein 0.0043 0.0464 0.0464
Echinococcus granulosus Protein patched homolog 1 0.0044 0.0487 0.0487
Loa Loa (eye worm) hypothetical protein 0.0049 0.0549 0.0589
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0361 0.0387
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0378 0.0378
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0592 0.0636
Onchocerca volvulus Sepiapterin reductase homolog 0.0012 0.0031 0.0033
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0.0027 0.0029
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.1248 0.4119
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0157 0.0168
Brugia malayi Trypsin family protein 0.0101 0.1301 0.1397
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0028 0.0257 0.0257
Trypanosoma cruzi protein tyrosine phosphatase PRL 0.0022 0.0178 0.0499
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0157 0.0157
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0532 0.0532
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0157 0.0168
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0023 0.0189 0.0203
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0288 0.0288
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0884 0.1254
Schistosoma mansoni protein tyrosine phosphatase prl 0.0022 0.0178 0.0178
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0212 0.0612
Leishmania major DNA/RNA non-specific endonuclease-like protein 0.0185 0.249 0.8324
Toxoplasma gondii carbonyl reductase 1, putative 0.0012 0.0031 0.0013
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0012 0.0031 0.0031
Plasmodium vivax steroid dehydrogenase, putative 0.0012 0.0031 0.0045
Leishmania major tyrosine specific protein phosphatase, putative 0.0019 0.0132 0.0342
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0308 0.4239 0.4239
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0028 0.0257 0.0257
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Plasmodium falciparum protein tyrosine phosphatase 0.0022 0.0178 0.288
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0212 0.1424
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0031 0.0005
Echinococcus multilocularis transmembrane protease serine 3 0.0011 0.001 0.001
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1248 0.1788
Loa Loa (eye worm) hypothetical protein 0.0021 0.0157 0.0168
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0212 0.0227
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0175 0.0175
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0157 0.0168
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Brugia malayi endonuclease G, mitochondrial precursor 0.0185 0.249 0.2674
Entamoeba histolytica hypothetical protein, conserved 0.0012 0.0031 0.0025
Brugia malayi jmjC domain containing protein 0.0037 0.0378 0.0406
Echinococcus multilocularis retinol dehydrogenase 13 0.0012 0.0031 0.0031
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0403 0.0403
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0403 0.2907
Onchocerca volvulus 0.0019 0.0134 0.0144
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0403 0.0403
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0098 0.1248 0.134
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0011
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0741 0.2899
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Brugia malayi Niemann-Pick C1 protein precursor 0.0103 0.132 0.1418
Loa Loa (eye worm) hypothetical protein 0.0101 0.1301 0.1397
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0049 0.055 0.5
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0031 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0157 0.0168
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.0031 0.0126
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0031 0.0031
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.0031 0.0031
Echinococcus multilocularis conserved hypothetical protein 0.0012 0.0031 0.0031
Onchocerca volvulus 0.0032 0.031 0.0333
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Plasmodium vivax SET domain protein, putative 0.0062 0.0741 1
Schistosoma mansoni hypothetical protein 0.0011 0.001 0.001
Echinococcus granulosus hypothetical protein 0.0012 0.0031 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0434 0.0595
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Onchocerca volvulus 0.0493 0.6855 0.7361
Onchocerca volvulus Alhambra homolog 0.003 0.0288 0.031
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0012 0.0031 0.0025
Onchocerca volvulus 0.0012 0.0031 0.0033
Loa Loa (eye worm) hypothetical protein 0.003 0.0288 0.031
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Onchocerca volvulus 0.0012 0.0031 0.0033
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0477 0.0513
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0013
Schistosoma mansoni hypothetical protein 0.0049 0.0549 0.0549
Schistosoma mansoni coup transcription factor 0.0021 0.0157 0.0157
Brugia malayi hypothetical protein 0.0049 0.0549 0.0589
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Leishmania major protein tyrosine phosphatase-like protein 0.0022 0.0178 0.0499
Onchocerca volvulus 0.002 0.015 0.0161
Echinococcus granulosus GPCR family 2 0.0016 0.0092 0.0092
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0456 0.0456
Trypanosoma cruzi protein tyrosine phosphatase, putative 0.0022 0.0178 0.0499
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0157 0.0168
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0031 0.0005
Schistosoma mansoni chromobox protein 0.0072 0.0884 0.0884
Loa Loa (eye worm) hypothetical protein 0.0049 0.0549 0.0589
Onchocerca volvulus 0.0011 0.001 0.0011
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0049 0.0549 0.0549
Brugia malayi chromobox protein homolog 3 0.004 0.0434 0.0466
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0157 0.0157
Brugia malayi hypothetical protein 0.0049 0.0549 0.0589
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0031 0.0126
Trypanosoma cruzi protein tyrosine phosphatase, putative 0.0022 0.0178 0.0499
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0175 0.0175
Echinococcus multilocularis oxidoreductase 0.0012 0.0031 0.0031
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.1653 0.1653
Toxoplasma gondii aldehyde dehydrogenase 0.0126 0.1653 0.66
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0012 0.0031 0.0013
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0012 0.0031 0.0013
Echinococcus multilocularis transferase 0.0049 0.0549 0.0549
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0012 0.0031 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0157 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0135 0.0158
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0157 0.0168
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Brugia malayi dehydrogenases, short chain protein 2 0.0012 0.0031 0.0033
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0049 0.055 0.2123
Onchocerca volvulus 0.0012 0.0031 0.0033
Loa Loa (eye worm) hypothetical protein 0.0155 0.2055 0.2207
Schistosoma mansoni jumonji domain containing protein 0.0079 0.0975 0.0975
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0025 0.0211 0.0211
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.022 0.1278
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0031 0.0126
Giardia lamblia Kinase, PLK 0.0098 0.1248 1
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0049 0.055 1
Loa Loa (eye worm) hypothetical protein 0.0308 0.4239 0.4552
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.0031 0.0031
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0157 0.0168
Echinococcus granulosus Endonuclease G 0.0185 0.249 0.249
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0019 0.0132 0.0132
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0157 0.0157
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0031 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0741 0.0741
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.022 0.1278
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0403 0.0403
Onchocerca volvulus Ectonucleotide pyrophosphatase\/phosphodiesterase family member 7 homolog 0.0049 0.0549 0.0589
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0049 0.0549 0.0589
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0018
Loa Loa (eye worm) hypothetical protein 0.0021 0.0157 0.0168
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0173 0.2315 0.2486
Echinococcus multilocularis Endonuclease G 0.0185 0.249 0.249
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0031 0.0031
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0123 0.0567
Trypanosoma brucei GPI ethanolamine phosphate transferase 3, putative 0.0049 0.0549 0.1753
Echinococcus multilocularis L aminoadipate semialdehyde 0.0173 0.2315 0.2315
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.015 0.015
Echinococcus granulosus retinol dehydrogenase 11 0.0012 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0101 0.1301 0.1397
Echinococcus multilocularis muscleblind protein 1 0.0155 0.2055 0.2055
Echinococcus granulosus L aminoadipate semialdehyde 0.0173 0.2315 0.2315
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0403 0.0403
Schistosoma mansoni hypothetical protein 0.0012 0.0027 0.0027
Mycobacterium ulcerans short-chain dehydrogenase 0.0012 0.0031 0.0126
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0023 0.0189 0.0203
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0212 0.1228
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0157 0.0168
Toxoplasma gondii oxidoreductase, putative 0.0012 0.0031 0.0013
Schistosoma mansoni hypothetical protein 0.0011 0.001 0.001
Brugia malayi Pre-SET motif family protein 0.0062 0.0741 0.0796
Loa Loa (eye worm) hypothetical protein 0.002 0.015 0.0161
Loa Loa (eye worm) hypothetical protein 0.0308 0.4239 0.4552
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0011
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.1301 0.1301
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0011 0.001 0.001
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0067 0.0817 0.266
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0157 0.0157
Mycobacterium ulcerans oxidoreductase 0.0012 0.0031 0.0126
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Brugia malayi steroid hormone receptor 0.0021 0.0157 0.0168
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.0487 0.0487
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0029
Loa Loa (eye worm) CHromoDomain protein family member 0.0012 0.0027 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0157 0.0168
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Mycobacterium ulcerans short-chain type oxidoreductase 0.0012 0.0031 0.0126
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Loa Loa (eye worm) thrombospondin type 1 domain-containing protein 0.0666 0.9312 1
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Brugia malayi Thrombospondin type 1 domain containing protein 0.0666 0.9312 1
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0547 0.0761
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Echinococcus multilocularis chromobox protein 2 0.0012 0.0027 0.0027
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0067 0.0817 0.0817
Echinococcus granulosus chromobox protein 1 0.0072 0.0884 0.0884
Brugia malayi Trypsin family protein 0.0011 0.001 0.0011
Brugia malayi Trypsin-like protease protein 5 0.0011 0.001 0.0011
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0027 0.0027
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Brugia malayi hypothetical protein 0.0012 0.0031 0.0033
Loa Loa (eye worm) hypothetical protein 0.004 0.0434 0.0466
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0157 0.0157
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0744 0.0799
Echinococcus multilocularis glycoprotein Antigen 5 0.0011 0.001 0.001
Brugia malayi Heterochromatin protein 1 0.0072 0.0884 0.0949
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0031 0.0031
Echinococcus granulosus chromobox protein 1 0.0072 0.0884 0.0884
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0157 0.0157
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0212 0.1424
Schistosoma mansoni hypothetical protein 0.0043 0.0464 0.0464
Echinococcus multilocularis chromobox protein 1 0.0072 0.0884 0.0884
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Echinococcus multilocularis protein tyrosine phosphatase PRL 0.0022 0.0178 0.0178
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Brugia malayi Doublecortin family protein 0.002 0.015 0.0161
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0288 0.0288
Plasmodium falciparum LCCL domain-containing protein 0.002 0.015 0.2336
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Entamoeba histolytica hypothetical protein 0.0012 0.0031 0.0025
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0019 0.0132 0.0342
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1248 0.1788
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0103 0.132 1
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Schistosoma mansoni hypothetical protein 0.003 0.0288 0.0288
Schistosoma mansoni hypothetical protein 0.0043 0.0464 0.0464
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0012 0.0031 0.0031
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0532 0.0532
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0288 0.1059
Plasmodium falciparum GPI ethanolamine phosphate transferase 3, putative 0.0049 0.0549 0.9966
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0547 0.0761
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0308 0.4239 0.4239
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0126 0.1653 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0123 0.0132
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0012 0.0032 0.0032
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Loa Loa (eye worm) hypothetical protein 0.0021 0.0157 0.0168
Loa Loa (eye worm) hypothetical protein 0.0049 0.0549 0.0589
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.022 0.1278
Echinococcus multilocularis citrate lyase subunit beta protein 0.0025 0.022 0.022
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0157 0.0168
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0012 0.0031 0.0126
Leishmania major phosphopantetheinyl transferase-like protein 0.0049 0.055 0.1759
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0027 0.0027
Brugia malayi hypothetical protein 0.002 0.015 0.0161
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0031 0.0031
Echinococcus granulosus protein tyrosine phosphatase PRL 0.0022 0.0178 0.0178
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0288 0.0288
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0157 0.0157
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0108 0.0479
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0067 0.0817 0.0817
Onchocerca volvulus 0.0012 0.0031 0.0033
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0011 0.001 0.001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0532 0.0532
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0067 0.0817 0.4912
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0123 0.1821
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0012 0.0031 0.0013
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0157 0.0168
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0011 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0212 0.0227
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0403 0.1261
Schistosoma mansoni hypothetical protein 0.0049 0.0549 0.0549
Onchocerca volvulus 0.0074 0.0909 0.0976
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0157 0.0157
Entamoeba histolytica serine/threonine protein kinase, putative 0.0098 0.1248 0.9439
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0487 0.0673
Trypanosoma brucei phosphatase of regenerating liver-type phosphatase, putative 0.0022 0.0178 0.0499
Loa Loa (eye worm) hypothetical protein 0.0019 0.0123 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0266 0.035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0157 0.0168
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0477 0.0659
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0031 0.0031
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0049 0.055 1
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0308 0.4239 0.4552
Loa Loa (eye worm) hypothetical protein 0.0035 0.0361 0.0387
Plasmodium falciparum phd finger protein, putative 0.003 0.0288 0.4988
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0126 0.1653 0.1653
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Loa Loa (eye worm) hypothetical protein 0.0021 0.0157 0.0168
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0012 0.0031 0.0033
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0013
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0031 0.0031
Brugia malayi hypothetical protein 0.0012 0.0031 0.0033
Leishmania major protein tyrosine phosphatase-likie protein 0.0022 0.0178 0.0499
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0017 0.0018
Schistosoma mansoni hypothetical protein 0.0016 0.0092 0.0092
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.015 0.015
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0157 0.0157
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0074 0.0909 0.0909
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0031 0.0005
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0126 0.1653 0.5489
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0212 0.0612
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1248 0.1788
Echinococcus granulosus enteropeptidase 0.0011 0.001 0.001
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0012 0.0031 0.0031
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0403 0.1261
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0011 0.001 0.001
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0403 0.055
Echinococcus granulosus expressed conserved protein 0.0097 0.1232 0.1232
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0157 0.0157
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0126 0.1653 0.1653
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0012 0.0031 0.0005
Schistosoma mansoni hypothetical protein 0.0666 0.9312 0.9312
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0028 0.0257 0.0257
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Trypanosoma brucei endonuclease G, putative 0.0185 0.249 0.8324
Echinococcus multilocularis steroid dehydrogenase 0.0012 0.0031 0.0031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0157 0.0168
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0027 0.0027
Brugia malayi nuclear receptor NHR-88 0.0021 0.0157 0.0168
Echinococcus multilocularis RUN 0.002 0.015 0.015
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0012 0.0027 0.0027
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0157 0.0168
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0012 0.0031 0.0025
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0022 0.0175 0.0175
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.022 0.064
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.1248 0.1248
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0646 0.0694
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.0027 0.0029
Onchocerca volvulus 0.0308 0.4239 0.4552
Mycobacterium ulcerans dehydrogenase 0.0012 0.0031 0.0126
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0012 0.0031 0.0126
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0029
Toxoplasma gondii hypothetical protein 0.0019 0.0135 0.0438
Loa Loa (eye worm) doublecortin family protein 0.002 0.015 0.0161
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0012 0.0031 0.0005
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0013
Echinococcus granulosus transferase 0.0049 0.0549 0.0549
Schistosoma mansoni carbonyl reductase 0.0012 0.0031 0.0031
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Entamoeba histolytica short chain dehydrogenase family protein 0.0012 0.0031 0.0025
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0099 0.1263 0.1263
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0185 0.249 0.8324
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0012 0.0031 0.0031
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0031 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0018
Schistosoma mansoni hypothetical protein 0.0016 0.0092 0.0092
Schistosoma mansoni carbonyl reductase 0.0012 0.0031 0.0031
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0012 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0043 0.0464 0.0464
Echinococcus granulosus glycoprotein Antigen 5 0.0011 0.001 0.001
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0049 0.055 0.329
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.026 0.355 0.355
Schistosoma mansoni microtubule-associated protein tau 0.0714 1 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0092 0.0098
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0018
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0025 0.022 0.0282
Loa Loa (eye worm) hypothetical protein 0.0021 0.0157 0.0168
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0022 0.0175 0.0188
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0108 0.0479
Loa Loa (eye worm) dehydrogenase 0.0012 0.0031 0.0033
Onchocerca volvulus 0.0012 0.0031 0.0033
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0092 0.0092
Schistosoma mansoni hypothetical protein 0.002 0.015 0.015
Onchocerca volvulus 0.0012 0.0031 0.0033
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0108 0.0479
Onchocerca volvulus 0.0091 0.1151 0.1236
Echinococcus multilocularis chromobox protein 1 0.0072 0.0884 0.0884
Leishmania major hypothetical protein, conserved 0.022 0.2986 1
Plasmodium vivax protein tyrosine phosphatase, putative 0.0022 0.0178 0.211
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0029
Echinococcus multilocularis transient receptor potential cation channel 0.0012 0.0031 0.0031
Onchocerca volvulus 0.002 0.015 0.0161
Entamoeba histolytica hypothetical protein 0.0049 0.055 0.4044
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0434 0.0595
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Echinococcus granulosus citrate lyase subunit beta protein 0.0025 0.022 0.022
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0027 0.0027
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0185 0.249 0.8324
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Onchocerca volvulus 0.0025 0.0212 0.0227
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0049 0.055 0.7325
Mycobacterium leprae hypothetical protein 0.0049 0.0549 0.9965
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0057 0.0671 0.0671
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0212 0.1228
Loa Loa (eye worm) hypothetical protein 0.0021 0.0157 0.0168
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.1248 0.4119
Brugia malayi hypothetical protein 0.002 0.015 0.0161
Leishmania major endonuclease G, putative 0.0185 0.249 0.8324
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0266 0.035
Brugia malayi oxidoreductase 0.0012 0.0031 0.0033
Schistosoma mansoni polycystin 1-related 0.002 0.015 0.015
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0032 0.0035
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0157 0.0157
Loa Loa (eye worm) type I phosphodiesterase/nucleotide pyrophosphatase 0.0049 0.0549 0.0589
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0017 0.0017
Trypanosoma brucei endonuclease G, putative 0.0185 0.249 0.8324
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Echinococcus multilocularis carbonyl reductase 1 0.0012 0.0031 0.0031
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0012 0.0031 0.0033
Schistosoma mansoni chromobox protein 0.0012 0.0027 0.0027
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0049 0.0549 0.0549
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0029
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Echinococcus granulosus RUN 0.002 0.015 0.015
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0028 0.0257 0.0257
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0532 0.0532
Brugia malayi jmjC domain containing protein 0.0099 0.1263 0.1356
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0403 0.0403
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0212 0.1228
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0212 0.0227
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0212 0.1115
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.015 0.015
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1248 0.1788
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0049 0.055 1
Schistosoma mansoni hypothetical protein 0.0016 0.0092 0.0092
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0434 0.0466
Loa Loa (eye worm) hypothetical protein 0.002 0.015 0.0161
Brugia malayi dehydrogenases, short chain protein 9 0.0012 0.0031 0.0033
Trypanosoma cruzi protein tyrosine phosphatase-like protein, putative 0.0022 0.0178 0.0499
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0378 0.0378
Loa Loa (eye worm) hypothetical protein 0.0038 0.0403 0.0433
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0029
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Loa Loa (eye worm) hypothetical protein 0.0019 0.0123 0.0132
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0012 0.0031 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0157 0.0168
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0592 0.0636
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0012 0.0031 0.0126
Schistosoma mansoni hypothetical protein 0.0049 0.0549 0.0549
Loa Loa (eye worm) hypothetical protein 0.0016 0.0092 0.0098
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0018
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0288 0.1059
Echinococcus multilocularis GPCR, family 2 0.0016 0.0092 0.0092
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0104 0.1343 0.1343
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0012 0.0031 0.0033
Schistosoma mansoni chromobox protein 0.0012 0.0027 0.0027
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0157 0.0157
Onchocerca volvulus GPI ethanolamine phosphate transferase 2 homolog 0.0049 0.0549 0.0589
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0019 0.0132 0.0142
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0103 0.132 0.1418
Echinococcus multilocularis microtubule associated protein 2 0.0714 1 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0157 0.0168
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0433 0.6006 0.6449
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0099 0.1263 0.1263
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Onchocerca volvulus Ectonucleotide pyrophosphatase\/phosphodiesterase family member 6 homolog 0.0049 0.0549 0.0589
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0018
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0067 0.0817 0.0817
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0011 0.001 0.0011
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0157 0.0168
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0067 0.0817 0.0877
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0741 0.0741
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1248 0.1788
Loa Loa (eye worm) hypothetical protein 0.0018 0.0114 0.0122
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0049 0.0549 0.0549
Echinococcus multilocularis Alkaline phosphatase, core domain 0.0049 0.0549 0.0549
Schistosoma mansoni rab6-interacting 0.002 0.015 0.015
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0012 0.0031 0.0025
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.1248 0.1788
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0592 0.0636
Loa Loa (eye worm) hypothetical protein 0.0062 0.0741 0.0796
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0098 0.1248 0.1248
Schistosoma mansoni hypothetical protein 0.0035 0.0361 0.0361
Onchocerca volvulus 0.0012 0.0031 0.0033
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Echinococcus multilocularis protein dispatched 1 0.005 0.0575 0.0575
Onchocerca volvulus 0.0173 0.2315 0.2486
Loa Loa (eye worm) hypothetical protein 0.0044 0.0487 0.0523
Plasmodium falciparum steroid dehydrogenase, putative 0.0012 0.0031 0.0062
Loa Loa (eye worm) hypothetical protein 0.0021 0.0157 0.0168
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0532 0.0571
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Mycobacterium tuberculosis Conserved protein 0.0025 0.022 0.1166
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0067 0.0817 0.4912
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0212 0.1424
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.0031 0.0031
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0157 0.0157
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0012 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0011
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0017 0.0017
Echinococcus granulosus gpi ethanolamine phosphate transferase 3 0.0049 0.0549 0.0549
Onchocerca volvulus 0.0666 0.9312 1
Echinococcus multilocularis Chromo domain 0.0012 0.0027 0.0027
Loa Loa (eye worm) helicase 0.0012 0.0027 0.0029
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0157 0.0157
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0123 0.1334
Schistosoma mansoni chromobox protein 0.0072 0.0884 0.0884
Loa Loa (eye worm) hypothetical protein 0.0049 0.0549 0.0589
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0212 0.3481
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0288 0.031
Echinococcus granulosus carbonyl reductase 1 0.0012 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0403 0.055
Trypanosoma brucei polo-like protein kinase 0.0098 0.1248 0.4119
Loa Loa (eye worm) hypothetical protein 0.0173 0.2315 0.2486
Giardia lamblia PHD finger protein 15 0.003 0.0288 0.2116
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0212 0.3481
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Schistosoma mansoni kinase 0.005 0.0565 0.0565
Brugia malayi AEL166Cp 0.0049 0.0549 0.0589
Brugia malayi Pre-SET motif family protein 0.0433 0.6006 0.6449
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0157 0.0168
Brugia malayi serine/threonine-protein kinase plk-2 0.0098 0.1248 0.134
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0157 0.0157
Schistosoma mansoni lipoxygenase 0.002 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0025 0.0212 0.0227
Loa Loa (eye worm) hypothetical protein 0.0025 0.0212 0.0227
Mycobacterium ulcerans dehydrogenase/reductase 0.0012 0.0031 0.0126
Loa Loa (eye worm) hypothetical protein 0.0052 0.0594 0.0638
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0308 0.4239 0.4239
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Mycobacterium ulcerans hypothetical protein 0.0025 0.022 0.1278
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0049 0.0549 0.0549
Trypanosoma cruzi hypothetical protein, conserved 0.022 0.2986 1
Echinococcus granulosus oxidoreductase 0.0012 0.0031 0.0031
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1653 1
Entamoeba histolytica phosphatidylinositol-glycan biosynthesis class O protein, putative 0.0049 0.0549 0.403
Onchocerca volvulus GPI ethanolamine phosphate transferase 3 homolog 0.0049 0.0549 0.0589
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0017 0.0018
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0157 0.0168
Loa Loa (eye worm) hypothetical protein 0.0308 0.4239 0.4552
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0477 0.0659
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0012 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0123 0.0687
Schistosoma mansoni lipoxygenase 0.0057 0.0671 0.0671
Loa Loa (eye worm) hypothetical protein 0.0019 0.0123 0.0132
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0031 0.0005
Loa Loa (eye worm) hypothetical protein 0.0052 0.0592 0.0636
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0012 0.0031 0.0033
Echinococcus granulosus hypothetical protein 0.0012 0.0031 0.0031
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0012 0.0031 0.0062
Echinococcus granulosus chromobox protein 2 0.0012 0.0027 0.0027
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0157 0.0157
Schistosoma mansoni rab6-interacting 0.002 0.015 0.015
Brugia malayi hypothetical protein 0.0011 0.0017 0.0018
Onchocerca volvulus 0.0012 0.0027 0.0029
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0022 0.0178 0.1165
Echinococcus granulosus WW domain containing oxidoreductase 0.0012 0.0031 0.0031
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Echinococcus multilocularis retinol dehydrogenase 11 0.0012 0.0031 0.0031
Brugia malayi Trypsin family protein 0.0011 0.001 0.0011
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0092 0.0098
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0049 0.0549 0.0549
Onchocerca volvulus 0.0011 0.001 0.0011
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0403 0.1261
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0092 0.0092
Echinococcus multilocularis Niemann Pick C1 protein 0.0147 0.1947 0.1947
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0157 0.0168
Loa Loa (eye worm) hypothetical protein 0.0021 0.0157 0.0168
Brugia malayi hypothetical protein 0.0011 0.0017 0.0018
Onchocerca volvulus 0.0012 0.0031 0.0033
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0157 0.0157
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0173 0.2315 0.2315
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.0031 0.0126
Schistosoma mansoni patched 1 0.0044 0.0487 0.0487
Echinococcus granulosus muscleblind protein 0.0155 0.2055 0.2055
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1653 1
Brugia malayi Protein cec-1. 0.0012 0.0027 0.0029
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0017 0.0017
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0031 0.0005
Echinococcus multilocularis protein patched 0.0044 0.0487 0.0487
Trypanosoma cruzi protein tyrosine phosphatase-like protein, putative 0.0022 0.0178 0.0499
Brugia malayi nuclear hormone receptor 0.0021 0.0157 0.0168
Entamoeba histolytica short chain dehydrogenase family protein 0.0012 0.0031 0.0025
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0212 0.1228
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0157 0.0157
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0019 0.0132 0.0132
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0741 0.0741
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.015 0.1711
Brugia malayi hypothetical protein 0.0012 0.0027 0.0029
Trypanosoma cruzi protein tyrosine phosphatase-like protein, putative 0.0022 0.0178 0.0499
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0212 0.1228
Onchocerca volvulus Serine\/threonine kinase homolog 0.0098 0.1248 0.134
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0012 0.0031 0.0005
Brugia malayi M-phase phosphoprotein, mpp8 0.0012 0.0027 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.022 0.2986 1
Schistosoma mansoni endonuclease related 0.0185 0.249 0.249
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0011
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0028 0.0257 0.0257
Loa Loa (eye worm) hypothetical protein 0.0155 0.2055 0.2207
Brugia malayi PHD-finger family protein 0.003 0.0288 0.031
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0067 0.0817 0.4846
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Loa Loa (eye worm) oxidoreductase 0.0012 0.0031 0.0033
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0212 0.1115
Echinococcus multilocularis Niemann Pick C1 protein 0.0103 0.132 0.132
Onchocerca volvulus 0.0308 0.4239 0.4552
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0157 0.0157
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0157 0.0168
Brugia malayi Trypsin family protein 0.0011 0.001 0.0011
Schistosoma mansoni protein tyrosine phosphatase prl 0.0022 0.0178 0.0178
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.0487 0.0523
Schistosoma mansoni loxhd1 0.002 0.015 0.015
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0378 0.0406
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0033
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0017 0.0018
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0011
Brugia malayi Muscleblind-like protein 0.0155 0.2055 0.2207
Giardia lamblia Phosphatidylinositol-glycan biosynthesis, class O protein 0.0049 0.0549 0.4255
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0012 0.0031 0.0126
Toxoplasma gondii oxidoreductase, putative 0.0012 0.0031 0.0013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0157 0.0157
Mycobacterium ulcerans oxidoreductase 0.0012 0.0031 0.0126
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0378 0.0378
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0012 0.0031 0.0033
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0308 0.4239 0.4239
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0098 0.1248 0.4119
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0157 0.0157
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.015 0.015
Trypanosoma brucei hypothetical protein, conserved 0.022 0.2986 1
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0012 0.0031 0.0005
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0022 0.0175 0.0175
Echinococcus multilocularis Mastin 0.0011 0.001 0.001
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0403 0.3061
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0092 0.0092
Schistosoma mansoni retinal dehydrogenase 0.0012 0.0031 0.0031
Loa Loa (eye worm) trypsin family protein 0.0011 0.001 0.0011
Trypanosoma cruzi protein tyrosine phosphatase, putative 0.0022 0.0178 0.0499
Echinococcus multilocularis enteropeptidase 0.0011 0.001 0.001
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0403 0.1261
Brugia malayi hypothetical protein 0.0011 0.001 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0403 0.055
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0741 0.0741
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0212 0.1228
Brugia malayi Dehydrogenases, short chain protein 2 0.0012 0.0031 0.0033
Entamoeba histolytica hypothetical protein, conserved 0.0012 0.0031 0.0025
Schistosoma mansoni hypothetical protein 0.0016 0.0092 0.0092
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0029
Loa Loa (eye worm) hypothetical protein 0.0032 0.031 0.0333
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0157 0.0157
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0532 0.0571
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.022 0.064
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0157 0.0168
Brugia malayi nuclear receptor RXR 0.0011 0.0017 0.0018
Onchocerca volvulus 0.0019 0.0132 0.0142
Echinococcus granulosus transmembrane protease serine 3 0.0011 0.001 0.001
Mycobacterium ulcerans hypothetical protein 0.0025 0.0212 0.1228
Entamoeba histolytica phosphatidylinositol-glycan biosynthesis class O protein, putative 0.0049 0.0549 0.403
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0033
Schistosoma mansoni carbonyl reductase 0.0012 0.0031 0.0031
Brugia malayi ecdysteroid receptor 0.0021 0.0157 0.0168
Echinococcus granulosus Niemann Pick C1 protein 0.0103 0.132 0.132
Loa Loa (eye worm) hypothetical protein 0.0019 0.0123 0.0132
Onchocerca volvulus 0.0012 0.0031 0.0033
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0403 0.0403
Echinococcus granulosus ectonucleotide 0.026 0.355 0.355
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0157 0.0157
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0157 0.0168
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1653 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0157 0.0168
Mycobacterium leprae conserved hypothetical protein 0.0049 0.055 1
Mycobacterium ulcerans carveol-like dehydrogenase 0.0012 0.0031 0.0126
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0012 0.0027 0.0027
Schistosoma mansoni short chain dehydrogenase 0.0012 0.0031 0.0031
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0049 0.0549 0.0589
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0157 0.0157
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0049 0.055 0.329
Brugia malayi Dehydrogenases, short chain protein 30 0.0012 0.0031 0.0033
Loa Loa (eye worm) hypothetical protein 0.0018 0.0122 0.0131
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0012 0.0027 0.0027
Echinococcus multilocularis gpi ethanolamine phosphate transferase 1 0.0049 0.0549 0.0549
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0308 0.4239 0.4239
Echinococcus granulosus steroid dehydrogenase 0.0012 0.0031 0.0031
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0532 0.0532
Loa Loa (eye worm) hypothetical protein 0.0054 0.0628 0.0674
Onchocerca volvulus 0.0012 0.0031 0.0033
Echinococcus granulosus peregrin 0.003 0.0288 0.0288
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0049 0.055 0.3204
Leishmania major ethanolamine phosphotransferase, putative 0.0049 0.0549 0.1753
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0012 0.0031 0.0025
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0011 0.001 0.001
Brugia malayi Bromodomain containing protein 0.003 0.0288 0.031
Echinococcus multilocularis expressed conserved protein 0.0097 0.1232 0.1232
Onchocerca volvulus 0.0101 0.1301 0.1397
Brugia malayi Retinol dehydrogenase 12 0.0012 0.0031 0.0033
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0057 0.0671 0.0671
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.022 0.064
Mycobacterium ulcerans ketoacyl reductase 0.0012 0.0031 0.0126
Onchocerca volvulus 0.0021 0.0157 0.0168
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.0884 0.0949
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0011 0.001 0.001
Trypanosoma brucei hypothetical protein, conserved 0.0049 0.055 0.1759
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0157 0.0157
Trypanosoma brucei endonuclease G, putative 0.0185 0.249 0.8324
Schistosoma mansoni cercarial elastase (S01 family) 0.0011 0.001 0.001
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.1301 0.1301
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.022 0.1166
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0012 0.0031 0.0013
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0011 0.001 0.001
Trichomonas vaginalis steroid dehydrogenase, putative 0.0012 0.0031 0.0005
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0011 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.026 0.355 0.3812
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0456 0.0456
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0019 0.0132 0.0132
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0092 0.0098
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0532 0.0532
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0108 0.0479
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0019 0.0132 0.0342
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.026 0.355 0.355
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0012 0.0027 0.0027
Mycobacterium ulcerans hypothetical protein 0.0025 0.022 0.1278
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0741 0.0741
Mycobacterium ulcerans hypothetical protein 0.0049 0.0549 0.3279
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Schistosoma mansoni steroid dehydrogenase 0.0012 0.0031 0.0031
Toxoplasma gondii DNA/RNA non-specific endonuclease 0.0185 0.249 1
Onchocerca volvulus 0.0011 0.001 0.0011
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0049 0.055 0.2123
Echinococcus multilocularis gpi ethanolamine phosphate transferase 3 0.0049 0.0549 0.0549
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0741 0.0741
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0157 0.0168
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0157 0.0157
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0011 0.001 0.001
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0157 0.0157
Echinococcus granulosus Chromo domain 0.0012 0.0027 0.0027
Mycobacterium ulcerans short chain dehydrogenase 0.0012 0.0031 0.0126
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0012 0.0031 0.0126
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0011 0.001 0.001
Echinococcus granulosus Mastin 0.0011 0.001 0.001
Echinococcus multilocularis sortilin receptor 0.0015 0.0078 0.0078
Onchocerca volvulus 0.0012 0.0027 0.0029

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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