Detailed information for compound 708625

Basic information

Technical information
  • TDR Targets ID: 708625
  • Name: N-ethyl-N-(2-methylphenyl)-4-(propanoylamino) benzamide
  • MW: 310.39 | Formula: C19H22N2O2
  • H donors: 1 H acceptors: 2 LogP: 3.32 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN(c1ccccc1C)C(=O)c1ccc(cc1)NC(=O)CC
  • InChi: 1S/C19H22N2O2/c1-4-18(22)20-16-12-10-15(11-13-16)19(23)21(5-2)17-9-7-6-8-14(17)3/h6-13H,4-5H2,1-3H3,(H,20,22)
  • InChiKey: TWKAGPOMEJGQSS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-ethyl-N-(2-methylphenyl)-4-(1-oxopropylamino)benzamide
  • N-ethyl-N-(2-methylphenyl)-4-propionamido-benzamide
  • ZINC04814392
  • STK218124

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0119 0.0712
Schistosoma mansoni smad 0.0026 0.0052 0.0107
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.032 0.1785
Schistosoma mansoni hypothetical protein 0.0018 0.0004 0.0008
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0288 0.1629 1
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0007 0.0018
Leishmania major DNA damage repair protein, putative 0.0019 0.0012 0.0046
Giardia lamblia Kinase, CMGC MAPK 0.0056 0.023 0.1395
Brugia malayi Cell death protein 3 precursor 0.0032 0.0088 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0059 0.0337
Brugia malayi hypothetical protein 0.017 0.0917 0.1105
Brugia malayi jmjC domain containing protein 0.0035 0.0104 0.0121
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.027 0.1504
Echinococcus granulosus tar DNA binding protein 0.0123 0.0635 0.0768
Loa Loa (eye worm) hypothetical protein 0.0035 0.0104 0.0121
Echinococcus multilocularis peptidase Clp (S14 family) 0.0056 0.023 0.023
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0084 0.0174
Brugia malayi jmjC domain containing protein 0.0035 0.0104 0.0121
Onchocerca volvulus 0.0018 0.0007 0.0028
Plasmodium vivax vivapain-2 0.0018 0.0007 0.0079
Entamoeba histolytica deoxycytidyl transferase, putative 0.0062 0.027 0.1638
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0148 0.0784 0.4411
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0059 0.0337
Loa Loa (eye worm) hypothetical protein 0.0097 0.0479 0.0575
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0059 0.0337
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0267 0.0553
Brugia malayi hypothetical protein 0.015 0.0798 0.096
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0104 0.0121
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.032 0.1785
Schistosoma mansoni cpg binding protein 0.0128 0.0667 0.1382
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0007 0.002
Brugia malayi steroid hormone receptor 0.0031 0.0084 0.0097
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0479 0.0479
Plasmodium vivax ataxin-2 like protein, putative 0.0075 0.0349 0.8572
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0025 0.0047 0.0242
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0059 0.0337
Loa Loa (eye worm) TAR-binding protein 0.0123 0.0635 0.0764
Echinococcus multilocularis phd:f box containing protein 0.0035 0.0104 0.0104
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0071 0.0324 0.0387
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0044 0.0158 0.0186
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.0479 0.0574
Loa Loa (eye worm) hypothetical protein 0.0138 0.0724 0.0871
Onchocerca volvulus 0.0032 0.0088 0.0749
Echinococcus granulosus cpg binding protein 0.0128 0.0667 0.0806
Schistosoma mansoni hypothetical protein 0.0284 0.1604 0.3323
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0118 0.0605 0.3401
Brugia malayi Probable ClpP-like protease 0.0085 0.0406 0.0487
Brugia malayi ecdysteroid receptor 0.0031 0.0084 0.0097
Loa Loa (eye worm) hypothetical protein 0.0085 0.0406 0.0487
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0084 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0084 0.0097
Trypanosoma cruzi DNA damage repair protein, putative 0.0019 0.0012 0.0046
Echinococcus multilocularis fetal alzheimer antigen, falz 0.003 0.0075 0.0075
Trypanosoma brucei unspecified product 0.0043 0.0154 0.0848
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0084 0.0097
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0059 0.0252 0.03
Schistosoma mansoni survival motor neuron protein 0.0106 0.0537 0.1112
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0505 0.3088
Brugia malayi CHE-14 protein 0.0042 0.0146 0.0172
Plasmodium falciparum JmjC domain-containing protein, putative 0.0035 0.0104 0.2493
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0588 0.3436 1
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0007 0.0014
Loa Loa (eye worm) hypothetical protein 0.0037 0.0119 0.014
Leishmania major hypothetical protein, conserved 0.0048 0.0184 0.102
Loa Loa (eye worm) hypothetical protein 0.005 0.0198 0.0234
Echinococcus granulosus zinc finger protein 0.0027 0.0056 0.0068
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0007 0.0028
Echinococcus granulosus zinc phosphodiesterase 0.0018 0.0004 0.0005
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0479 0.0479
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0037 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0035 0.0104 0.0121
Trypanosoma brucei DNA polymerase eta, putative 0.0116 0.0595 0.334
Entamoeba histolytica hypothetical protein 0.0155 0.0829 0.5077
Loa Loa (eye worm) hypothetical protein 0.0032 0.0088 0.0102
Schistosoma mansoni ran 0.0044 0.0158 0.0327
Trichomonas vaginalis helicase, putative 0.0027 0.0059 0.0337
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0044 0.0158 0.0158
Schistosoma mansoni ferritin 0.0026 0.0055 0.0114
Loa Loa (eye worm) hypothetical protein 0.0072 0.0328 0.0392
Loa Loa (eye worm) hypothetical protein 0.0037 0.0119 0.014
Echinococcus multilocularis kelch ECH associated protein 1 0.0204 0.1121 0.1121
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0123 0.0635 0.0764
Echinococcus granulosus survival motor neuron protein 1 0.0522 0.3039 0.3673
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0224 0.0465
Loa Loa (eye worm) ctsf protein 0.0018 0.0007 0.0004
Echinococcus granulosus dna polymerase eta 0.0116 0.0595 0.0719
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0119 0.0337
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0119 0.0337
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0505 0.3088
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0085 0.0406 0.3175
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0071 0.0324 0.0392
Brugia malayi Importin beta-1 subunit 0.0059 0.0252 0.03
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.0349 0.8572
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0084 0.0097
Schistosoma mansoni ferritin light chain 0.0026 0.0055 0.0114
Schistosoma mansoni transcription factor LCR-F1 0.0155 0.0829 0.1717
Trypanosoma brucei chrX additional, unordered contigs 0.0019 0.0012 0.0046
Echinococcus multilocularis caspase 2 0.0032 0.0088 0.0088
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0007 0.0004
Schistosoma mansoni DNA polymerase eta 0.0116 0.0595 0.1232
Leishmania major basic transcription factor 3a, putative 0.0034 0.0103 0.0561
Echinococcus granulosus hydroxyacylglutathione hydrolase 0.0018 0.0004 0.0005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0007 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0154 0.0848
Onchocerca volvulus 0.0031 0.0084 0.0716
Echinococcus granulosus JmjC domain containing protein 4 0.0035 0.0104 0.0126
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0119 0.0654
Loa Loa (eye worm) hypothetical protein 0.0075 0.0349 0.0417
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0119 0.0654
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0012 0.0046
Schistosoma mansoni tsg101-related 0.0125 0.0647 0.1341
Schistosoma mansoni Smad4 0.0026 0.0052 0.0107
Onchocerca volvulus 0.0037 0.0119 0.1032
Schistosoma mansoni transcription factor btf3 0.0034 0.0103 0.0213
Echinococcus granulosus ubiquitin specific protease 41 0.0118 0.0605 0.0732
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0025 0.0047 0.0242
Entamoeba histolytica serine/threonine protein kinase, putative 0.0204 0.1124 0.6898
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0007 0.0007
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0052 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0084 0.0097
Schistosoma mansoni jumonji domain containing protein 0.0035 0.0104 0.0216
Echinococcus multilocularis Smad4 0.0026 0.0052 0.0052
Schistosoma mansoni jumonji/arid domain-containing protein 0.0139 0.073 0.1513
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0025 0.0047 0.0242
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0084 0.0174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0007 0.002
Loa Loa (eye worm) hypothetical protein 0.0051 0.0203 0.024
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0479 0.0579
Brugia malayi MH2 domain containing protein 0.0026 0.0052 0.0058
Schistosoma mansoni ets-related 0.0247 0.1382 0.2864
Trypanosoma brucei beta lactamase 0.0209 0.1153 0.6496
Schistosoma mansoni protein phosphatase 2C 0.0035 0.0104 0.0216
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0007 0.0004
Brugia malayi ImpB/MucB/SamB family protein 0.0062 0.027 0.0322
Echinococcus granulosus mixed lineage leukemia protein mll 0.003 0.0074 0.009
Echinococcus multilocularis tar DNA binding protein 0.0123 0.0635 0.0635
Loa Loa (eye worm) hypothetical protein 0.015 0.0798 0.096
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0025 0.0047 0.0242
Trypanosoma brucei protein kinase, putative 0.0056 0.023 0.1281
Mycobacterium ulcerans bacterioferritin BfrA 0.0026 0.0055 0.015
Schistosoma mansoni hypothetical protein 0.0819 0.4826 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.027 0.1504
Echinococcus granulosus caspase 2 0.0032 0.0088 0.0106
Brugia malayi PHD-finger family protein 0.0032 0.0089 0.0103
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0084 0.0097
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.0349 0.1951
Mycobacterium tuberculosis Conserved hypothetical protein 0.0164 0.0884 0.2566
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0007 0.002
Echinococcus multilocularis protein patched 0.0042 0.0146 0.0146
Echinococcus multilocularis transcription factor btf3 0.0034 0.0103 0.0103
Trypanosoma cruzi DNA polymerase eta, putative 0.0116 0.0595 0.334
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.027 0.1504
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0047 0.0264
Schistosoma mansoni coup transcription factor 0.0031 0.0084 0.0174
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0084 0.0174
Echinococcus multilocularis zinc phosphodiesterase 0.0018 0.0004 0.0004
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0035 0.0104 0.0567
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.027 0.1504
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0204 0.1124 0.6335
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0479 0.0575
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0479 0.2927
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0084 0.0097
Echinococcus multilocularis expressed protein 0.0026 0.0055 0.0055
Echinococcus granulosus expressed protein 0.0026 0.0055 0.0067
Brugia malayi beta-lactamase 0.0037 0.0119 0.014
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.016 0.0881
Echinococcus granulosus expressed conserved protein 0.0091 0.0444 0.0537
Schistosoma mansoni hypothetical protein 0.0155 0.0829 0.1717
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0052 0.0058
Brugia malayi beta-lactamase family protein 0.0037 0.0119 0.014
Onchocerca volvulus 0.0018 0.0007 0.0028
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0252 0.1402
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0043 0.0157 0.0157
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0119 0.0119
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0119 0.0337
Loa Loa (eye worm) CXXC zinc finger family protein 0.0119 0.0615 0.0739
Loa Loa (eye worm) hypothetical protein 0.0035 0.0104 0.0121
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0012 0.0046
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0084 0.0084
Echinococcus multilocularis JmjC domain containing protein 4 0.0035 0.0104 0.0104
Plasmodium vivax DNA repair protein REV1, putative 0.0019 0.0012 0.02
Echinococcus multilocularis Kelch repeat type 1 0.0204 0.1125 0.1125
Toxoplasma gondii cathepsin CPL 0.0018 0.0007 0.0025
Echinococcus granulosus geminin 0.0697 0.4095 0.4949
Schistosoma mansoni hypothetical protein 0.004 0.0137 0.0284
Plasmodium falciparum importin beta, putative 0.0059 0.0252 0.616
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.032 0.1785
Echinococcus multilocularis X box binding protein 1 0.0284 0.1604 0.1604
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.027 0.1504
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1629 1
Echinococcus granulosus GA binding protein alpha chain 0.0081 0.0385 0.0466
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0267 0.0767
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0012 0.0046
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0064 0.0283 0.1577
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0084 0.0097
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0312 0.1773 1
Echinococcus multilocularis expressed conserved protein 0.0091 0.0444 0.0444
Echinococcus multilocularis muscleblind protein 1 0.1392 0.8275 0.8275
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0209 0.1153 0.3348
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0007 0.0018
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0155 0.0829 0.1001
Brugia malayi Bromodomain containing protein 0.0039 0.013 0.0153
Schistosoma mansoni caspase-7 (C14 family) 0.0032 0.0088 0.0182
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0119 0.0248
Loa Loa (eye worm) hypothetical protein 0.0031 0.0084 0.0097
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0104 0.0121
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0000023027
Mycobacterium tuberculosis Conserved protein 0.0037 0.0119 0.0337
Loa Loa (eye worm) hypothetical protein 0.0031 0.0084 0.0097
Echinococcus granulosus mitogen activated protein kinase 3 0.0056 0.023 0.0279
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0085 0.0406 0.1173
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0007 0.0008
Schistosoma mansoni terminal deoxycytidyl transferase 0.0062 0.027 0.0559
Trypanosoma brucei unspecified product 0.0043 0.0154 0.0848
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0084 0.0097
Brugia malayi RNA, U transporter 1 0.0168 0.0908 0.1094
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0059 0.0337
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.027 0.1504
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.016 0.0881
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0118 0.0605 0.3401
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0019 0.0012 0.0064
Schistosoma mansoni hypothetical protein 0.0106 0.0537 0.1112
Trypanosoma cruzi cruzipain precursor, putative 0.007 0.032 0.1785
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.023 0.1281
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0084 0.0174
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0025 0.0047 0.0242
Echinococcus multilocularis dna polymerase kappa 0.0062 0.027 0.027
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0084 0.0097
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.023 0.1281
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1629 1
Brugia malayi Cathepsin L-like precursor 0.0018 0.0007 0.0004
Loa Loa (eye worm) metallo-beta-lactamase superfamily protein 0.0018 0.0004 0.0000023027
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0588 0.3436 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0084 0.0084
Schistosoma mansoni bromodomain containing protein 0.0071 0.0324 0.0671
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0052 0.0107
Mycobacterium leprae Probable lipase LipE 0.0037 0.0119 0.0337
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0085 0.0406 0.1173
Loa Loa (eye worm) hydroxyacylglutathione hydrolase cytoplasmic 0.0018 0.0004 0.0000023027
Schistosoma mansoni tar DNA-binding protein 0.0123 0.0635 0.1317
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0084 0.0084
Schistosoma mansoni hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) 0.0018 0.0004 0.0008
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0103 0.0782
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0007 0.002
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0084 0.0102
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0148 0.0784 0.4411
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0084 0.0084
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0085 0.0406 0.0406
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0084 0.0174
Echinococcus granulosus ETHE1 protein 0.0018 0.0004 0.0005
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0267 0.0553
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0118 0.0605 0.0727
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0059 0.0337
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.002 0.0016 0.0033
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0119 0.0337
Mycobacterium tuberculosis Conserved protein 0.0037 0.0119 0.0337
Brugia malayi Cathepsin L-like precursor 0.0018 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0031 0.0084 0.0097
Echinococcus multilocularis geminin 0.0697 0.4095 0.4095
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0025 0.0047 0.0242
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.023 0.1395
Schistosoma mansoni tsg101-related 0.0125 0.0647 0.1341
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.023 0.0478
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0154 0.0848
Echinococcus multilocularis apoptotic protease activating factor 1 0.0032 0.0088 0.0088
Brugia malayi jmjC domain containing protein 0.0035 0.0104 0.0121
Onchocerca volvulus 0.0037 0.0119 0.1032
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0007 0.0008
Brugia malayi nuclear hormone receptor 0.0031 0.0084 0.0097
Echinococcus multilocularis GA binding protein alpha chain 0.0081 0.0385 0.0385
Trichomonas vaginalis ferritin, putative 0.0026 0.0055 0.0317
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.027 0.1504
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0056 0.023 0.1281
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0048 0.0184 0.102
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.032 0.1785
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0025 0.0047 0.0242
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0085 0.0406 1
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0056 0.023 0.1281
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0059 0.0337
Echinococcus granulosus kelch ECH associated protein 1 like 0.0204 0.1121 0.1355
Toxoplasma gondii hypothetical protein 0.0029 0.0072 0.0535
Loa Loa (eye worm) hypothetical protein 0.007 0.0314 0.0375
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0000023027
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0119 0.0712
Loa Loa (eye worm) RNA binding protein 0.0123 0.0635 0.0764
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0084 0.0102
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0007 0.0007
Schistosoma mansoni cpg binding protein 0.0119 0.0615 0.1273
Echinococcus granulosus metallo beta lactamase domain containing protein 0.0018 0.0004 0.0005
Leishmania major cathepsin L-like protease 0.007 0.032 0.1785
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0237 0.1325 0.385
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.027 0.1504
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1629 1
Trichomonas vaginalis esterase, putative 0.0037 0.0119 0.0712
Schistosoma mansoni tar DNA-binding protein 0.0123 0.0635 0.1317
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0103 0.0611
Echinococcus granulosus ferritin 0.0026 0.0055 0.0067
Loa Loa (eye worm) beta-lactamase 0.0037 0.0119 0.014
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0044 0.0158 0.0948
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0435 0.2515 0.7316
Schistosoma mansoni zinc phosphodiesterase 0.0018 0.0004 0.0008
Echinococcus multilocularis ETHE1 protein 0.0018 0.0004 0.0004
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0025 0.0047 0.0242
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0071 0.0324 0.1972
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.032 0.1785
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0007 0.002
Schistosoma mansoni tar DNA-binding protein 0.0123 0.0635 0.1317
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0119 0.0712
Loa Loa (eye worm) hypothetical protein 0.0031 0.0084 0.0097
Mycobacterium ulcerans beta-lactamase 0.0037 0.0119 0.0337
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0204 0.1124 0.1359
Trichomonas vaginalis CAMK family protein kinase 0.0204 0.1124 0.6898
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0059 0.0337
Entamoeba histolytica hypothetical protein 0.0025 0.0047 0.0264
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0007 0.002
Echinococcus multilocularis jumonji domain containing 1A 0.0035 0.0104 0.0104
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0118 0.0605 0.1254
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0324 0.1811
Leishmania major cathepsin L-like protease 0.007 0.032 0.1785
Schistosoma mansoni patched 1 0.0042 0.0146 0.0303
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0071 0.0324 0.0387
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0119 0.0712
Brugia malayi MAP kinase sur-1 0.0056 0.023 0.0274
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0084 0.0716
Brugia malayi F/Y-rich N-terminus family protein 0.0038 0.0127 0.0149
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0119 0.0654
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0158 0.0871
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0479 0.0992
Trichomonas vaginalis hypothetical protein 0.0073 0.0335 0.204
Echinococcus granulosus importin subunit beta 1 0.0059 0.0252 0.0304
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0118 0.0605 0.3703
Loa Loa (eye worm) hypothetical protein 0.0037 0.0119 0.014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0007 0.002
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0488 0.1012
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0119 0.014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0007 0.002
Echinococcus granulosus jumonji domain containing 1A 0.0035 0.0104 0.0126
Leishmania major cathepsin L-like protease 0.0018 0.0007 0.0018
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0267 0.2076
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0217 0.1207
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0084 0.0097
Echinococcus multilocularis metallo beta lactamase domain containing protein 0.0018 0.0004 0.0004
Loa Loa (eye worm) Smad1 0.0026 0.0052 0.0058
Mycobacterium tuberculosis Conserved protein 0.0037 0.0119 0.0337
Trichomonas vaginalis CAMK family protein kinase 0.0204 0.1124 0.6898
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.027 0.1504
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0062 0.027 0.0326
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0267 0.0767
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.0349 0.8572
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0007 0.002
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0025 0.0047 0.0242
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.016 0.0881
Echinococcus granulosus GTP binding nuclear protein Ran 0.0044 0.0158 0.0191
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0119 0.0144
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0267 0.0767
Brugia malayi Fli-1 protein 0.0247 0.1382 0.1667
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0071 0.0324 0.0672
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0084 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0007 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0059 0.0337
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.032 0.1785
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0037 0.0118 0.0143
Loa Loa (eye worm) fli-1 protein 0.0247 0.1382 0.1667
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0312 0.1773 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.013 0.0677 0.0677
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.016 0.0881
Trichomonas vaginalis CAMK family protein kinase 0.0204 0.1124 0.6898
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0026 0.0055 0.015
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0026 0.0055 0.015
Giardia lamblia Fructose-bisphosphate aldolase 0.0288 0.1629 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0084 0.0097
Entamoeba histolytica hypothetical protein 0.0155 0.0829 0.5077
Schistosoma mansoni gabp alpha 0.0081 0.0385 0.0798
Echinococcus granulosus Niemann Pick C1 protein 0.0139 0.073 0.0882
Onchocerca volvulus 0.0018 0.0007 0.0028
Brugia malayi jmjC domain containing protein 0.013 0.0677 0.0815
Schistosoma mansoni apoferritin-2 0.0026 0.0055 0.0114
Schistosoma mansoni jumonji domain containing protein 0.013 0.0677 0.1404
Loa Loa (eye worm) hydroxyacylglutathione hydrolase 0.0018 0.0004 0.0000023027
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0052 0.0062
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0146 0.0172
Trypanosoma cruzi DNA damage repair protein, putative 0.0019 0.0012 0.0046
Echinococcus multilocularis mitogen activated protein kinase 3 0.0056 0.023 0.023
Schistosoma mansoni hypothetical protein 0.004 0.0137 0.0284
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0479 0.0579
Entamoeba histolytica hypothetical protein 0.0155 0.0829 0.5077
Schistosoma mansoni hypothetical protein 0.0018 0.0004 0.0008
Onchocerca volvulus 0.0018 0.0007 0.0028
Brugia malayi Cathepsin L-like precursor 0.0018 0.0007 0.0004
Loa Loa (eye worm) MH2 domain-containing protein 0.038 0.2186 0.2638
Schistosoma mansoni smad1 5 8 and 0.0026 0.0052 0.0107
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0084 0.0097
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0118 0.0605 0.3401
Loa Loa (eye worm) hypothetical protein 0.0037 0.0119 0.014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0084 0.0097
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0267 0.0767
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0084 0.0102
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0118 0.0605 0.0605
Trypanosoma brucei DNA damage repair protein, putative 0.0019 0.0012 0.0046
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0267 0.0267
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0044 0.0158 0.3825
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0044 0.0158 0.1214
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0056 0.023 0.0661
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0059 0.0337
Brugia malayi MH1 domain containing protein 0.0026 0.0052 0.0058
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0044 0.0158 0.0186
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0007 0.0028
Brugia malayi Cathepsin L-like precursor 0.0018 0.0007 0.0004
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0072 0.1686
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0155 0.0829 0.0829
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0025 0.0047 0.0242
Schistosoma mansoni hypothetical protein 0.004 0.0137 0.0284
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0074 0.0154
Leishmania major DNA polymerase eta, putative 0.0073 0.0337 0.1881
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0252 0.1402
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0085 0.0406 1
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0144 0.0144
Echinococcus multilocularis zinc finger protein 0.0027 0.0056 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.027 0.1504
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0084 0.0084
Entamoeba histolytica hypothetical protein 0.0025 0.0047 0.0264
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0119 0.0248
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0605 0.3703
Entamoeba histolytica hypothetical protein 0.0025 0.0047 0.0264
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0019 0.0012 0.0064
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0118 0.0605 0.3401
Echinococcus multilocularis tumor protein p63 0.0373 0.2141 0.2141
Schistosoma mansoni hypothetical protein 0.004 0.0137 0.0284
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.023 0.1395
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0084 0.0102
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0084 0.0102
Echinococcus multilocularis Niemann Pick C1 protein 0.0139 0.073 0.073
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0043 0.0157 0.019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.032 0.1785
Loa Loa (eye worm) hypothetical protein 0.0116 0.0595 0.0714
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0084 0.0084
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.023 0.1395
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0479 0.0992
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.032 0.1785
Brugia malayi hypothetical protein 0.0032 0.0088 0.0102
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0025 0.0047 0.0242
Echinococcus multilocularis dnaJ subfamily B 0.0819 0.4826 0.4826
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0085 0.0406 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0007 0.002
Echinococcus granulosus lysine specific demethylase 6a 0.0035 0.0104 0.0126
Brugia malayi MH2 domain containing protein 0.038 0.2186 0.2638
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0059 0.0337
Schistosoma mansoni zinc finger protein 0.0027 0.0056 0.0117
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0062 0.027 0.0775
Echinococcus granulosus metallo beta lactamase domain containing protein 0.0018 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0031 0.0084 0.0097
Schistosoma mansoni peptidase Clp (S14 family) 0.0085 0.0406 0.0842
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0119 0.014
Loa Loa (eye worm) fibroinase 0.0018 0.0007 0.0004
Mycobacterium ulcerans bacterioferritin BfrB 0.0026 0.0055 0.015
Echinococcus multilocularis cpg binding protein 0.0128 0.0667 0.0667
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0035 0.0104 0.0792
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.0479 0.0574
Leishmania major cathepsin L-like protease 0.007 0.032 0.1785
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.002 0.0016 0.0016
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0073 0.0337 0.2624
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0084 0.0716
Schistosoma mansoni phosphatidylserine receptor 0.0035 0.0104 0.0216
Echinococcus multilocularis survival motor neuron protein 1 0.0522 0.3039 0.3039
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0062 0.027 0.0559
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0007 0.002
Schistosoma mansoni jumonji/arid domain-containing protein 0.0139 0.073 0.1513
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0071 0.0324 0.1811
Echinococcus granulosus cathepsin l1 0.0018 0.0007 0.0008
Mycobacterium tuberculosis Conserved hypothetical protein 0.0062 0.027 0.0775
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.0184 0.1021
Brugia malayi RNA binding protein 0.0123 0.0635 0.0764
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0184 0.1112
Trypanosoma brucei DNA damage repair protein, putative 0.0019 0.0012 0.0046
Brugia malayi Ets-domain containing protein 0.0081 0.0385 0.0461
Echinococcus multilocularis hydroxyacylglutathione hydrolase 0.0018 0.0004 0.0004
Echinococcus multilocularis kelch ECH associated protein 1 0.0204 0.1121 0.1121
Toxoplasma gondii ABC1 family protein 0.0037 0.0119 0.0912
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0102 0.051 0.3113
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0026 0.0055 0.1277
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0172
Giardia lamblia DNA damage repair protein 0.0019 0.0012 0.005
Schistosoma mansoni ran 0.0044 0.0158 0.0327
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0084 0.0174
Echinococcus granulosus muscleblind protein 0.1392 0.8275 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0084 0.0097
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0084 0.0174
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1629 1
Onchocerca volvulus 0.0055 0.0224 0.1968
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0007 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.027 0.1504
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0085 0.0406 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1629 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.0349 0.1951
Schistosoma mansoni kinase 0.0104 0.0522 0.1081
Echinococcus granulosus dna polymerase kappa 0.0062 0.027 0.0326
Echinococcus granulosus phd:f box containing protein 0.0035 0.0104 0.0126
Onchocerca volvulus 0.0018 0.0007 0.0028
Onchocerca volvulus Huntingtin homolog 0.0138 0.0724 0.6427
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0084 0.0097
Schistosoma mansoni ferritin 0.0026 0.0055 0.0114
Echinococcus multilocularis importin subunit beta 1 0.0059 0.0252 0.0252
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0148 0.0784 0.4411
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1629 1
Schistosoma mansoni tar DNA-binding protein 0.0123 0.0635 0.1317
Leishmania major importin beta-1 subunit, putative 0.0048 0.0184 0.1021
Brugia malayi hypothetical protein 0.0155 0.0829 0.0997
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0059 0.0337
Echinococcus granulosus dnaJ subfamily B 0.0819 0.4826 0.5833
Echinococcus granulosus snurportin 1 0.0631 0.3698 0.4469
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.1124 0.233
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0119 0.0337
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0118 0.0605 0.1254
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0204 0.1124 0.1124
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0084 0.0097
Onchocerca volvulus 0.0018 0.0007 0.0028
Trypanosoma cruzi polo-like protein kinase, putative 0.0204 0.1124 0.6335
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1629 1
Schistosoma mansoni hypothetical protein 0.0204 0.1125 0.233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0007 0.002
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0071 0.0324 0.0324
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0007 0.0079
Schistosoma mansoni smad1 5 8 and 0.0026 0.0052 0.0107
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0085 0.0406 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0062 0.027 0.1504
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0118 0.0605 0.3703
Echinococcus multilocularis mitogen activated protein kinase 0.0056 0.023 0.023
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0119 0.0337
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0118 0.0605 0.3703
Trypanosoma cruzi DNA polymerase eta, putative 0.0073 0.0337 0.1881
Loa Loa (eye worm) jmjC domain-containing protein 0.0139 0.073 0.0878
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0103 0.0611
Echinococcus multilocularis dna polymerase eta 0.0116 0.0595 0.0595
Onchocerca volvulus Huntingtin homolog 0.0138 0.0724 0.6427
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0084 0.0174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0007 0.002
Echinococcus granulosus tumor susceptibility gene 101 protein 0.015 0.0798 0.0964
Leishmania major DNA polymerase kappa, putative 0.0062 0.027 0.1504
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0267 0.1489
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0084 0.0084
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.002 0.0016 0.0033
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0056 0.023 0.1281
Brugia malayi Cytochrome P450 family protein 0.0053 0.0212 0.0252
Loa Loa (eye worm) cysteine protease 0.0018 0.0007 0.0004
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0141 0.0742 0.2151
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.0588 0.3436 1
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.032 0.1785
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0119 0.0337
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0103 0.0561
Mycobacterium ulcerans lipase LipD 0.0037 0.0119 0.0337
Schistosoma mansoni hypothetical protein 0.0631 0.3698 0.7662
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0007 0.002
Schistosoma mansoni hypothetical protein 0.0021 0.0022 0.0045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.032 0.1785
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0288 0.1629 1
Echinococcus multilocularis cysteine protease 0.0018 0.0007 0.0007
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0007 0.0079
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0146 0.0177
Brugia malayi MH2 domain containing protein 0.0026 0.0052 0.0058
Echinococcus granulosus smad 0.0026 0.0052 0.0062
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0146 0.0146
Schistosoma mansoni hypothetical protein 0.0034 0.0099 0.0205
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.027 0.1504
Brugia malayi Smad1 0.0026 0.0052 0.0058
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0106 0.0537 0.0644
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0056 0.023 0.1787
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0085 0.0406 0.1173
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0631 0.3698 0.4466
Trypanosoma brucei PAB1-binding protein , putative 0.0075 0.0349 0.1951
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0324 0.1811
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0067 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0031 0.0084 0.0097
Trichomonas vaginalis CAMK family protein kinase 0.0204 0.1124 0.6898
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0119 0.0337
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0144 0.0174
Echinococcus granulosus X box binding protein 1 0.0284 0.1604 0.1938
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0212 0.0252
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0059 0.0337
Brugia malayi Muscleblind-like protein 0.1392 0.8275 1
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0044 0.0158 0.0871
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0074 0.0074
Schistosoma mansoni apoferritin-2 0.0026 0.0055 0.0114
Brugia malayi hypothetical protein 0.0049 0.0188 0.0223
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0084 0.0097
Entamoeba histolytica cysteine protease, putative 0.0018 0.0007 0.002
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0084 0.0097
Brugia malayi beta-NAC-like protein 0.0034 0.0103 0.012
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0007 0.0004
Echinococcus granulosus kelch ECH associated protein 1 like 0.0204 0.1121 0.1355
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0044 0.0158 0.3825
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0007 0.0079
Onchocerca volvulus 0.017 0.0917 0.8152
Mycobacterium ulcerans hypothetical protein 0.0164 0.0884 0.2566
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0141 0.0742 0.2151
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.013 0.0677 0.0819
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0074 0.009
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0085 0.0406 0.2479
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0035 0.0104 0.0567
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0104 0.0121
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0312 0.1773 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0145 0.0171
Schistosoma mansoni importin beta-1 0.0059 0.0252 0.0522
Treponema pallidum fructose-bisphosphate aldolase 0.0288 0.1629 1
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0084 0.0174
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0048 0.0184 0.102
Brugia malayi nuclear receptor NHR-88 0.0031 0.0084 0.0097
Entamoeba histolytica Ran family GTPase 0.0044 0.0158 0.0948
Brugia malayi Cathepsin L-like precursor 0.0018 0.0007 0.0004
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0056 0.023 0.0274
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0007 0.0014
Echinococcus granulosus Smad4 0.0026 0.0052 0.0062
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.023 0.1395
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0067 0.0302 0.0365
Giardia lamblia DINP protein human, muc B family 0.0062 0.027 0.1638
Echinococcus multilocularis protein dispatched 1 0.0047 0.0182 0.0182
Entamoeba histolytica hypothetical protein 0.0025 0.0047 0.0264
Plasmodium falciparum DNA repair protein REV1, putative 0.0019 0.0012 0.02
Leishmania major DNA polymerase kappa, putative 0.0019 0.0012 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0103 0.0611
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0084 0.0174
Echinococcus granulosus transcription factor btf3 0.0034 0.0103 0.0124
Treponema pallidum bacterioferrin (TpF1) 0.0026 0.0055 0.0317
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0084 0.0097
Schistosoma mansoni hypothetical protein 0.0032 0.0088 0.0182
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0479 0.0992
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0084 0.0097
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0099 0.012
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0099 0.0099
Brugia malayi Bromodomain containing protein 0.0083 0.0395 0.0474
Brugia malayi Cathepsin L-like precursor 0.0018 0.0007 0.0004
Trichomonas vaginalis DNA polymerase eta, putative 0.0062 0.027 0.1638
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0056 0.023 0.1281
Echinococcus granulosus peptidase Clp S14 family 0.0056 0.023 0.0279
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0084 0.0097
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0084 0.0102
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0007 0.0028
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0103 0.0561
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0119 0.0337
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.027 0.1504
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.027 0.1504
Entamoeba histolytica hypothetical protein 0.0155 0.0829 0.5077
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0184 0.1112
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0209 0.1153 0.3348
Leishmania major hypothetical protein, conserved 0.0035 0.0104 0.0567
Echinococcus granulosus mitogen activated protein kinase 0.0056 0.023 0.0279
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0026 0.0055 0.015
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0084 0.0102
Leishmania major DNA polymerase eta, putative 0.0116 0.0595 0.334
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0435 0.2515 0.7316
Mycobacterium ulcerans hypothetical protein 0.0037 0.0119 0.0337
Onchocerca volvulus Serine\/threonine kinase homolog 0.0204 0.1124 1
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0141 0.0742 0.2151
Loa Loa (eye worm) hypothetical protein 0.0522 0.3039 0.367
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0062 0.027 0.1638
Echinococcus multilocularis ferritin 0.0026 0.0055 0.0055
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0146 0.0177
Brugia malayi MH1 domain containing protein 0.0026 0.0052 0.0058
Leishmania major mitochondrial DNA polymerase beta 0.0312 0.1773 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0119 0.014
Echinococcus granulosus histone lysine methyltransferase setb 0.002 0.0016 0.0019
Echinococcus multilocularis lysine specific demethylase 6a 0.0035 0.0104 0.0104
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0084 0.0174
Leishmania major cathepsin L-like protease 0.0018 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0039 0.013 0.0153
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.003 0.0075 0.0155
Mycobacterium ulcerans lipoprotein LpqF 0.0209 0.1153 0.3348
Toxoplasma gondii HEAT repeat-containing protein 0.0059 0.0252 0.1956
Echinococcus granulosus lysine specific demethylase 5A 0.0139 0.073 0.0882
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0056 0.023 0.0661
Schistosoma mansoni cpg binding protein 0.0128 0.0667 0.1382
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0047 0.0264
Brugia malayi Ets-domain containing protein 0.0081 0.0385 0.0461
Loa Loa (eye worm) hypothetical protein 0.1392 0.8275 1
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0119 0.0712
Brugia malayi beta-lactamase family protein 0.0037 0.0119 0.014
Loa Loa (eye worm) hypothetical protein 0.0031 0.0084 0.0097
Loa Loa (eye worm) hypothetical protein 0.1392 0.8275 1
Leishmania major cathepsin L-like protease 0.0018 0.0007 0.0018
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0084 0.0097
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0025 0.0047 0.0242
Brugia malayi RNA recognition motif domain containing protein 0.0123 0.0635 0.0764
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0081 0.0385 0.0461
Leishmania major cathepsin L-like protease 0.0018 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0000023027
Plasmodium vivax JmjC domain containing protein 0.0035 0.0104 0.2493
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0479 0.0479
Plasmodium vivax importin-beta 2, putative 0.0059 0.0252 0.616
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0085 0.0406 0.3175
Echinococcus multilocularis ubiquitin specific protease 41 0.0118 0.0605 0.0605
Entamoeba histolytica hypothetical protein 0.0048 0.0184 0.1112
Leishmania major hypothetical protein, conserved 0.0037 0.0119 0.0654
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0146 0.0876
Loa Loa (eye worm) hypothetical protein 0.017 0.0917 0.1105
Mycobacterium ulcerans hypothetical protein 0.0019 0.0012 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0007 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0007 0.002
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0253 0.1421 0.2943
Toxoplasma gondii hypothetical protein 0.005 0.0198 0.1535
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.032 0.1785
Echinococcus granulosus tumor protein p63 0.0373 0.2141 0.2587
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0084 0.0102
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0119 0.2873
Schistosoma mansoni ferritin 0.0026 0.0055 0.0114
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0084 0.0084
Onchocerca volvulus 0.0037 0.0119 0.1032
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0029 0.0072 0.1686
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0007 0.002
Echinococcus multilocularis mixed lineage leukemia protein mll 0.003 0.0074 0.0074
Trypanosoma brucei unspecified product 0.0062 0.027 0.1504
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0267 0.0323
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0007 0.002
Echinococcus granulosus kelch ECH associated protein 1 0.0204 0.1121 0.1355
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0047 0.0242
Loa Loa (eye worm) transcription factor SMAD2 0.038 0.2186 0.2638
Brugia malayi CXXC zinc finger family protein 0.0119 0.0615 0.0738
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0084 0.0097
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0029 0.0072 0.0198
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0103 0.2463
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0007 0.0007
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0035 0.0104 0.0216
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0158 0.0871
Loa Loa (eye worm) hypothetical protein 0.002 0.0016 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0007 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0059 0.0337
Echinococcus multilocularis smad 0.0026 0.0052 0.0052
Echinococcus multilocularis snurportin 1 0.0631 0.3698 0.3698
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0007 0.002
Schistosoma mansoni phd/f-box containing protein 0.0035 0.0104 0.0216
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0035 0.0104 0.0792
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0085 0.0406 0.0491
Echinococcus granulosus apoptotic protease activating factor 1 0.0032 0.0088 0.0106
Loa Loa (eye worm) hypothetical protein 0.0032 0.0088 0.0102
Brugia malayi jmjC domain containing protein 0.0139 0.073 0.0878
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.027 0.1504
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0052 0.0052
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0007 0.002
Echinococcus multilocularis lysine specific demethylase 5A 0.013 0.0677 0.0677
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0007 0.002
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0062 0.027 0.0322
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0047 0.0242
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0072 0.0418
Trypanosoma cruzi polo-like protein kinase, putative 0.0204 0.1124 0.6335
Loa Loa (eye worm) hypothetical protein 0.0118 0.0605 0.0727
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0012 0.0046
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0022 0.0022
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0084 0.0716
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.015 0.0798 0.0798
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.032 0.1785
Echinococcus granulosus fetal alzheimer antigen falz 0.003 0.0075 0.009
Schistosoma mansoni tsg101-related 0.0102 0.051 0.1056
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0012 0.0046
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0084 0.0174
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0118 0.0605 0.0732
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.027 0.1504
Onchocerca volvulus 0.0106 0.0537 0.4757
Leishmania major hypothetical protein, conserved 0.0075 0.0349 0.1951
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0059 0.0337
Brugia malayi hypothetical protein 0.0075 0.0349 0.0417
Brugia malayi polk-prov protein 0.0019 0.0012 0.001
Trypanosoma brucei polo-like protein kinase 0.0204 0.1124 0.6335
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.1629 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0138 0.0724 0.0871
Loa Loa (eye worm) hypothetical protein 0.0055 0.0224 0.0267
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0479 0.0579
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0062 0.027 0.027
Brugia malayi hypothetical protein 0.0138 0.0724 0.0871
Onchocerca volvulus 0.0018 0.0007 0.0028
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0324 0.1811
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.027 0.0775
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0052 0.0058
Onchocerca volvulus 0.0119 0.0615 0.545
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0204 0.1124 0.1355
Brugia malayi ImpB/MucB/SamB family protein 0.0116 0.0595 0.0714
Loa Loa (eye worm) hypothetical protein 0.0037 0.0119 0.014
Schistosoma mansoni hypothetical protein 0.0697 0.4095 0.8485
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0056 0.023 0.1281
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.032 0.1785
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0000023027
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0056 0.023 0.0661
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0007 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0204 0.1124 0.6898
Giardia lamblia Kinase, PLK 0.0204 0.1124 0.6898
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.027 0.0775
Schistosoma mansoni zinc phosphodiesterase 0.0018 0.0004 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0204 0.1124 0.6898
Brugia malayi hypothetical protein 0.0522 0.3039 0.367
Leishmania major cathepsin L-like protease 0.0018 0.0007 0.0018
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0118 0.0605 0.0605
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.027 0.1504
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0035 0.0104 0.0567
Trypanosoma cruzi major cysteine proteinase, putative 0.0055 0.0229 0.1272
Echinococcus multilocularis metallo beta lactamase domain containing protein 0.0018 0.0004 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0154 0.0848
Schistosoma mansoni ferritin 0.0026 0.0055 0.0114
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0103 0.0561
Leishmania major GTP-binding protein, putative 0.0044 0.0158 0.0871
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0103 0.0611
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0118 0.0605 0.3703
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0115 0.0115
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0118 0.0605 0.0732
Entamoeba histolytica hypothetical protein 0.0034 0.0103 0.0611
Loa Loa (eye worm) hypothetical protein 0.0031 0.0084 0.0097
Trichomonas vaginalis CAMK family protein kinase 0.0204 0.1124 0.6898
Schistosoma mansoni hypothetical protein 0.0018 0.0004 0.0008
Schistosoma mansoni tar DNA-binding protein 0.0123 0.0635 0.1317
Toxoplasma gondii histone lysine methyltransferase SET1 0.0229 0.1272 1
Schistosoma mansoni ferritin light chain 0.0026 0.0055 0.0114
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0007 0.002
Plasmodium vivax vivapain-2 0.0018 0.0007 0.0079
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0103 0.2463
Onchocerca volvulus Cell death protein 3 homolog 0.0032 0.0088 0.0749
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0012 0.0046
Brugia malayi jmjC domain containing protein 0.0035 0.0104 0.0121
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0059 0.0337
Brugia malayi TAR-binding protein 0.0123 0.0635 0.0764
Schistosoma mansoni hypothetical protein 0.0697 0.4095 0.8485
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0059 0.0337
Toxoplasma gondii LsmAD domain-containing protein 0.0075 0.0349 0.2722
Schistosoma mansoni DNA polymerase IV / kappa 0.0019 0.0012 0.0025
Trichomonas vaginalis ran, putative 0.0044 0.0158 0.0948
Echinococcus multilocularis cysteine protease 0.0018 0.0007 0.0007
Trichomonas vaginalis importin beta-1, putative 0.0048 0.0184 0.1112
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0084 0.0102
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0119 0.0337
Brugia malayi serine/threonine-protein kinase plk-2 0.0204 0.1124 0.1355
Loa Loa (eye worm) histone methyltransferase 0.0037 0.0118 0.0138
Echinococcus multilocularis muscleblind protein 0.1392 0.8275 0.8275
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.032 0.1785
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0115 0.014
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0103 0.012
Schistosoma mansoni smad1 5 8 and 0.0026 0.0052 0.0107

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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