Detailed information for compound 899516

Basic information

Technical information
  • TDR Targets ID: 899516
  • Name: 2-methylpropyl 2-ethyl-5-(3-fluorophenyl)-7-m ethyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine -6-carboxylate
  • MW: 390.472 | Formula: C20H23FN2O3S
  • H donors: 0 H acceptors: 2 LogP: 4.33 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC1SC2=NC(=C(C(N2C1=O)c1cccc(c1)F)C(=O)OCC(C)C)C
  • InChi: 1S/C20H23FN2O3S/c1-5-15-18(24)23-17(13-7-6-8-14(21)9-13)16(12(4)22-20(23)27-15)19(25)26-10-11(2)3/h6-9,11,15,17H,5,10H2,1-4H3
  • InChiKey: YNSPCVUYPPGNMV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • isobutyl 2-ethyl-5-(3-fluorophenyl)-7-methyl-3-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate
  • 2-ethyl-5-(3-fluorophenyl)-7-methyl-3-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxylic acid isobutyl ester
  • 2-ethyl-5-(3-fluorophenyl)-3-keto-7-methyl-5H-thiazolo[3,2-a]pyrimidine-6-carboxylic acid isobutyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0044 0.0218 0.0245
Echinococcus multilocularis nuclear receptor nhr 48 0.0044 0.0218 0.0245
Brugia malayi Papain family cysteine protease containing protein 0.0141 0.0933 0.1049
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0073 0.0432 0.2584
Loa Loa (eye worm) hypothetical protein 0.0096 0.0602 0.0677
Entamoeba histolytica hypothetical protein 0.0077 0.0463 0.2303
Echinococcus granulosus cathepsin b 0.1214 0.8892 1
Leishmania major cysteine peptidase A (CPA) 0.024 0.1669 0.5475
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Brugia malayi ShTK domain containing protein 0.0104 0.0659 0.0741
Leishmania major hypothetical protein, conserved 0.0043 0.0207 0.068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.1669 0.3105
Loa Loa (eye worm) hypothetical protein 0.0286 0.2012 0.2263
Onchocerca volvulus 0.0057 0.0311 0.0546
Brugia malayi cathepsin Z-like cysteine proteinase 0.0073 0.0432 0.0485
Trypanosoma cruzi major cysteine proteinase, putative 0.0073 0.0432 0.0485
Brugia malayi Ets-domain containing protein 0.0052 0.0273 0.0307
Toxoplasma gondii FATC domain-containing protein 0.0017 0.0018 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0073 0.0432 0.0802
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0291 0.2045 0.23
Giardia lamblia Cathepsin L precursor 0.0073 0.0432 0.1415
Onchocerca volvulus 0.0104 0.0659 0.1195
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0011 0.0012
Onchocerca volvulus 0.0094 0.0587 0.106
Loa Loa (eye worm) hypothetical protein 0.0029 0.0102 0.0114
Schistosoma mansoni cathepsin s 0.0068 0.0392 0.044
Leishmania major cathepsin L-like protease 0.024 0.1669 0.5475
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0026 0.0081 0.0266
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0166 0.1118 0.1258
Schistosoma mansoni tar DNA-binding protein 0.0249 0.1737 0.1954
Plasmodium vivax serine-repeat antigen (SERA) 0.0073 0.0432 0.2584
Mycobacterium ulcerans esterase/lipase LipP 0.0057 0.0311 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.1669 0.3105
Mycobacterium tuberculosis Probable hydrolase 0.0057 0.0311 0.0289
Echinococcus multilocularis peregrin 0.0051 0.0265 0.0298
Trichomonas vaginalis glycogen phosphorylase, putative 0.0144 0.0956 0.1779
Giardia lamblia DINP protein human, muc B family 0.0028 0.0097 0.0317
Echinococcus multilocularis geminin 0.0758 0.5506 0.6192
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0044 0.0218 0.0373
Loa Loa (eye worm) hypothetical protein 0.0057 0.0311 0.035
Brugia malayi nuclear receptor NHR-88 0.0094 0.0587 0.0659
Mycobacterium leprae conserved hypothetical protein 0.0057 0.0311 0.4787
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0094 0.0588 0.0661
Brugia malayi Patched related family protein 10 0.0017 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0044 0.0218 0.0246
Schistosoma mansoni tar DNA-binding protein 0.0249 0.1737 0.1954
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Entamoeba histolytica glycogen phosphorylase, putative 0.0144 0.0956 0.4753
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0034 0.0063
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0365 0.041
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0268 0.0498
Echinococcus multilocularis cathepsin b 0.1214 0.8892 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.024 0.1669 0.5475
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0166 0.1118 0.1258
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0319 0.2254 0.2535
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0014
Schistosoma mansoni DNA polymerase eta 0.0047 0.0235 0.0264
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0094 0.0587 0.0659
Entamoeba histolytica cysteine protease, putative 0.0141 0.0933 0.4638
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Leishmania major cathepsin L-like protease 0.024 0.1669 0.5475
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0077 0.0463 0.0521
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.1669 0.3105
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0096 0.0602 0.056
Echinococcus granulosus peregrin 0.0051 0.0265 0.0298
Echinococcus granulosus geminin 0.0758 0.5506 0.6192
Brugia malayi Myosin head containing protein 0.0017 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0044 0.0218 0.0246
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.005 0.0258 0.029
Plasmodium falciparum serine repeat antigen 1 0.0073 0.0432 0.2584
Giardia lamblia Cathepsin L precursor 0.0073 0.0432 0.1415
Brugia malayi PHD-finger family protein 0.0019 0.0033 0.0037
Echinococcus granulosus insulin receptor 0.013 0.0855 0.0962
Loa Loa (eye worm) patched family protein 0.0017 0.0018 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.1669 0.3105
Schistosoma mansoni gabp alpha 0.0052 0.0273 0.0307
Echinococcus multilocularis cathepsin L cysteine protease 0.024 0.1669 0.1877
Brugia malayi hypothetical protein 0.005 0.0258 0.029
Brugia malayi jmjC domain containing protein 0.0016 0.0011 0.0012
Schistosoma mansoni jumonji domain containing protein 0.0132 0.0866 0.0974
Echinococcus granulosus dna polymerase eta 0.0047 0.0235 0.0264
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0102 0.0189
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0094 0.0587 0.066
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Brugia malayi tailless protein 0.0044 0.0218 0.0245
Brugia malayi jmjC domain containing protein 0.0016 0.0011 0.0012
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0073 0.0432 0.2584
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0005 0.0006
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0011 0.0012
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0073 0.0432 0.0485
Trypanosoma brucei polo-like protein kinase 0.007 0.0405 0.1328
Schistosoma mansoni myelin transcription factor 1 myt1 0.0091 0.0567 0.0638
Brugia malayi Patched family protein 0.0017 0.0018 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0097 0.0317
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0073 0.0432 0.2584
Toxoplasma gondii cathepsin CPC1 0.0073 0.0432 0.1415
Echinococcus granulosus histone lysine methyltransferase setb 0.0094 0.0588 0.0661
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0018 0.0033
Schistosoma mansoni hypothetical protein 0.0035 0.0151 0.017
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0094 0.0587 0.0659
Brugia malayi hypothetical protein 0.0173 0.1171 0.1317
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.024 0.1669 0.3105
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0091 0.0567 0.0638
Loa Loa (eye worm) cathepsin B 0.0426 0.3048 0.3428
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0073 0.0432 0.2584
Toxoplasma gondii isocitrate dehydrogenase 0.0023 0.0057 0.0187
Echinococcus granulosus cpg binding protein 0.0052 0.0274 0.0307
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0023 0.0057 0.0064
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0062 0.0351 0.0332
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0028 0.0097 0.0109
Schistosoma mansoni tar DNA-binding protein 0.0249 0.1737 0.1954
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0311 0.035
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0005 0.0006
Loa Loa (eye worm) TAR-binding protein 0.0249 0.1737 0.1954
Trypanosoma cruzi cysteine protease, putative 0.0141 0.0933 0.105
Toxoplasma gondii histone lysine methyltransferase SET1 0.0096 0.0603 0.1978
Schistosoma mansoni cathepsin F (C01 family) 0.024 0.1669 0.1877
Giardia lamblia Cysteine protease 0.0073 0.0432 0.1415
Echinococcus granulosus sterol regulatory element binding protein 0.0123 0.0801 0.09
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0094 0.0587 0.0659
Toxoplasma gondii PHD-finger domain-containing protein 0.0017 0.0012 0.004
Echinococcus granulosus Niemann Pick C1 protein 0.0409 0.2923 0.3287
Brugia malayi Cathepsin L-like precursor 0.024 0.1669 0.1877
Loa Loa (eye worm) hypothetical protein 0.0019 0.0033 0.0037
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Brugia malayi cathepsin L-like cysteine proteinase 0.0073 0.0432 0.0485
Loa Loa (eye worm) hypothetical protein 0.0074 0.0439 0.0493
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0182 0.0339
Brugia malayi ecdysone receptor 0.0044 0.0218 0.0245
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0039 0.0182 0.0205
Loa Loa (eye worm) hypothetical protein 0.0308 0.2171 0.2441
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.0344 0.0386
Giardia lamblia Cathepsin B precursor 0.0073 0.0432 0.1415
Echinococcus multilocularis L aminoadipate semialdehyde 0.0074 0.0439 0.0493
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0094 0.0587 0.106
Echinococcus granulosus expressed conserved protein 0.0269 0.1883 0.2118
Brugia malayi nuclear receptor RXR 0.0044 0.0218 0.0245
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0096 0.0602 0.3605
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0057 0.0311 0.035
Onchocerca volvulus 0.024 0.1669 0.3081
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0081 0.0151
Plasmodium falciparum serine repeat antigen 8 0.0073 0.0432 0.2584
Echinococcus multilocularis importin subunit beta 1 0.002 0.004 0.0045
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0094 0.0588 0.0661
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0096 0.0602 0.0677
Brugia malayi PHD-finger family protein 0.0051 0.0265 0.0298
Brugia malayi cathepsin B-like cysteine proteinase 0.1214 0.8892 1
Echinococcus multilocularis jumonji domain containing protein 0.007 0.0412 0.0463
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0017 0.0013 0.0015
Brugia malayi serine/threonine-protein kinase plk-2 0.007 0.0405 0.0455
Schistosoma mansoni hypothetical protein 0.0051 0.0265 0.0298
Mycobacterium tuberculosis Conserved hypothetical protein 0.0096 0.0602 0.0603
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0044 0.0218 0.0245
Brugia malayi hypothetical protein 0.0017 0.0018 0.0021
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0005 0.0006
Loa Loa (eye worm) tyrosinase 1 0.0104 0.0659 0.0741
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0073 0.0432 0.0485
Echinococcus multilocularis cpg binding protein 0.0052 0.0274 0.0307
Trichomonas vaginalis CAMK family protein kinase 0.0035 0.0146 0.0272
Echinococcus multilocularis mitogen activated protein kinase 0.0039 0.0182 0.0205
Leishmania major T-complex protein 1, beta subunit, putative 0.0017 0.0013 0.0043
Onchocerca volvulus 0.0073 0.0432 0.0771
Schistosoma mansoni cathepsin C 0.0073 0.0432 0.0485
Brugia malayi Glycosyl hydrolases family 31 protein 0.0116 0.0753 0.0846
Loa Loa (eye worm) hypothetical protein 0.0044 0.0218 0.0246
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0091 0.0567 0.0638
Echinococcus multilocularis protein dispatched 1 0.014 0.0929 0.1045
Schistosoma mansoni cpg binding protein 0.0049 0.0253 0.0284
Trypanosoma brucei unspecified product 0.0019 0.0033 0.0106
Echinococcus granulosus lysosomal alpha glucosidase 0.0116 0.0753 0.0846
Onchocerca volvulus 0.0067 0.0389 0.0691
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0068 0.0392 0.044
Mycobacterium tuberculosis Possible oxidoreductase 0.0096 0.0602 0.0603
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0023 0.0057 0.0187
Mycobacterium ulcerans DNA polymerase IV 0.0028 0.0097 0.0053
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0012
Brugia malayi Bromodomain containing protein 0.0051 0.0265 0.0298
Brugia malayi Papain family cysteine protease containing protein 0.024 0.1669 0.1877
Brugia malayi hypothetical protein 0.0044 0.0218 0.0245
Plasmodium vivax unspecified product 0.0073 0.0432 0.2584
Echinococcus granulosus ecdysone induced protein 78C 0.0094 0.0587 0.0659
Onchocerca volvulus 0.008 0.0485 0.0871
Schistosoma mansoni coup transcription factor 0.0094 0.0587 0.0659
Echinococcus granulosus GA binding protein alpha chain 0.0052 0.0273 0.0307
Brugia malayi Heterochromatin protein 1 0.0051 0.0268 0.0301
Trypanosoma cruzi cruzipain precursor, putative 0.0068 0.0392 0.044
Brugia malayi latrophilin 2 splice variant baaae 0.021 0.1449 0.1629
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.008 0.0485 0.0545
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0021 0.0044 0.0264
Echinococcus granulosus insulin growth factor 1 receptor beta 0.013 0.0855 0.0962
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0016 0.0011 0.0021
Plasmodium falciparum lipid/sterol:H+ symporter 0.0017 0.0018 0.011
Plasmodium vivax patched family protein, putative 0.0017 0.0018 0.011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.1669 0.3105
Brugia malayi ImpB/MucB/SamB family protein 0.0028 0.0097 0.0109
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0096 0.0602 0.0677
Loa Loa (eye worm) hypothetical protein 0.0094 0.0587 0.066
Entamoeba histolytica cysteine protease, putative 0.0141 0.0933 0.4638
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0096 0.0602 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.1669 0.3105
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0698 0.5062 0.5693
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0011 0.0012
Toxoplasma gondii HEAT repeat-containing protein 0.002 0.004 0.013
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0308 0.2171 0.2441
Giardia lamblia Cathepsin L precursor 0.0073 0.0432 0.1415
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0033 0.0106
Plasmodium vivax importin-beta 2, putative 0.002 0.004 0.0237
Brugia malayi Cathepsin L-like precursor 0.024 0.1669 0.1877
Schistosoma mansoni tyrosine kinase 0.0216 0.1492 0.1678
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0141 0.0933 0.1736
Giardia lamblia Cathepsin B precursor 0.0426 0.3048 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.0392 0.044
Loa Loa (eye worm) hypothetical protein 0.0094 0.0587 0.066
Echinococcus granulosus neuropeptide s receptor 0.0722 0.5239 0.5892
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0094 0.0587 0.0659
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0073 0.0432 0.2584
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1214 0.8892 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0073 0.0432 0.1415
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Mycobacterium leprae Probable lipase LipE 0.0057 0.0311 0.4787
Mycobacterium tuberculosis Probable lipase LipE 0.0057 0.0311 0.0289
Loa Loa (eye worm) hypothetical protein 0.0044 0.0218 0.0246
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0011 0.0012
Schistosoma mansoni eyes absent homolog 0.0063 0.0356 0.0401
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0172 0.1167 0.2171
Loa Loa (eye worm) patched family protein 0.0017 0.0018 0.0021
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0039 0.0182 0.0597
Brugia malayi jmjC domain containing protein 0.0016 0.0011 0.0012
Onchocerca volvulus 0.024 0.1669 0.3081
Toxoplasma gondii t-complex protein beta subunit 0.0017 0.0013 0.0043
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0011 0.0012
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0094 0.0587 0.0659
Echinococcus granulosus chromobox protein 1 0.0051 0.0268 0.0301
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0104 0.0659 0.0741
Onchocerca volvulus Cathepsin L homolog 0.0073 0.0432 0.0771
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0097 0.0317
Loa Loa (eye worm) hypothetical protein 0.005 0.0258 0.029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.024 0.1669 0.5475
Trichomonas vaginalis CAMK family protein kinase 0.0035 0.0146 0.0272
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0365 0.041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.024 0.1669 0.5475
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0405 0.0753
Schistosoma mansoni tyrosinase precursor 0.0104 0.0659 0.0741
Loa Loa (eye worm) nuclear hormone receptor 0.0044 0.0218 0.0246
Loa Loa (eye worm) hypothetical protein 0.0104 0.0659 0.0741
Brugia malayi glutaminase DH11.1 0.0274 0.1924 0.2163
Echinococcus granulosus snurportin 1 0.0216 0.1491 0.1677
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0057 0.0311 0.035
Giardia lamblia Kinase, CMGC MAPK 0.0039 0.0182 0.0597
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0094 0.0587 0.0659
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.1669 0.3105
Toxoplasma gondii LsmAD domain-containing protein 0.0043 0.0207 0.068
Schistosoma mansoni cathepsin F (C01 family) 0.0172 0.1167 0.1313
Loa Loa (eye worm) patched family protein 0.0017 0.0018 0.0021
Loa Loa (eye worm) isocitrate dehydrogenase 0.0023 0.0057 0.0064
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0044 0.0218 0.0245
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0094 0.0587 0.0659
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0033 0.0106
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0426 0.3048 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0068 0.0392 0.044
Schistosoma mansoni survival motor neuron protein 0.0035 0.0151 0.017
Brugia malayi MAP kinase sur-1 0.0039 0.0182 0.0205
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0028 0.0097 0.0109
Echinococcus granulosus cathepsin l1 0.0172 0.1167 0.1313
Echinococcus granulosus cathepsin L cysteine proteinase 0.024 0.1669 0.1877
Brugia malayi chromobox protein homolog 3 0.0029 0.0102 0.0114
Echinococcus granulosus Niemann Pick C1 protein 0.0286 0.2012 0.2263
Trypanosoma cruzi PAB1-binding protein , putative 0.0043 0.0207 0.0233
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0029 0.0102 0.0155
Echinococcus multilocularis protein patched 0.0123 0.0801 0.09
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0011 0.0012
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0094 0.0587 0.0659
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0023 0.0057 0.0064
Loa Loa (eye worm) T-complex protein 1 0.0017 0.0013 0.0015
Mycobacterium tuberculosis Conserved protein 0.0057 0.0311 0.0289
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0034 0.0063
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0074 0.0439 0.0493
Plasmodium falciparum protoporphyrinogen oxidase 0.0096 0.0602 0.3605
Mycobacterium ulcerans monoamine oxidase 0.0096 0.0602 0.056
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0034 0.0063
Echinococcus granulosus lysine specific histone demethylase 1A 0.0096 0.0602 0.0677
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0021 0.0044 0.5
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0057 0.0311 0.0289
Loa Loa (eye worm) transcription factor SMAD2 0.0196 0.134 0.1506
Schistosoma mansoni glycogen phosphorylase 0.0144 0.0956 0.1075
Plasmodium vivax vivapain-2 0.024 0.1669 1
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0017 0.0012 0.004
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0073 0.0432 0.0485
Onchocerca volvulus Cathepsin L homolog 0.024 0.1669 0.3081
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0099 0.0624 0.2046
Schistosoma mansoni hypothetical protein 0.021 0.1449 0.1629
Trichomonas vaginalis esterase, putative 0.0057 0.0311 0.0578
Echinococcus granulosus epidermal growth factor receptor 0.0219 0.1512 0.17
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0073 0.0432 0.2584
Schistosoma mansoni chromobox protein 0.0051 0.0268 0.0301
Giardia lamblia Cysteine protease 0.0073 0.0432 0.1415
Mycobacterium tuberculosis Probable esterase LipL 0.0057 0.0311 0.0289
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0028 0.0097 0.0057
Echinococcus multilocularis lysosomal alpha glucosidase 0.0116 0.0753 0.0846
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0012
Schistosoma mansoni alpha-glucosidase 0.01 0.0632 0.0711
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0097 0.0317
Brugia malayi ImpB/MucB/SamB family protein 0.0047 0.0235 0.0264
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.1669 0.3105
Chlamydia trachomatis glycogen phosphorylase 0.0144 0.0956 1
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1214 0.8892 1
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0405 0.0753
Echinococcus multilocularis sterol regulatory element binding protein 0.0123 0.0801 0.09
Toxoplasma gondii cathepsin CPL 0.024 0.1669 0.5475
Echinococcus granulosus Nuclear hormone receptor HR96 0.0044 0.0218 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0073 0.0432 0.0802
Trichomonas vaginalis glutaminase, putative 0.0274 0.1924 0.3578
Echinococcus multilocularis 0.0096 0.0602 0.0677
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.024 0.1669 0.3105
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0405 0.0753
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0073 0.0432 0.0802
Loa Loa (eye worm) jmjC domain-containing protein 0.0104 0.0664 0.0747
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0094 0.0587 0.0659
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1214 0.8892 1
Schistosoma mansoni cpg binding protein 0.0052 0.0274 0.0307
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.024 0.1669 0.3105
Schistosoma mansoni alpha-glucosidase 0.01 0.0632 0.0711
Plasmodium vivax vivapain-1 0.0141 0.0933 0.5591
Trichomonas vaginalis D-aminoacylase, putative 0.0057 0.0311 0.0578
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0094 0.0587 0.0659
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0319 0.2254 0.2535
Mycobacterium ulcerans oxidoreductase 0.0096 0.0602 0.056
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0094 0.0587 0.0659
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0057 0.0311 0.0289
Trypanosoma cruzi DNA polymerase eta, putative 0.0027 0.0092 0.0104
Trypanosoma brucei protein kinase, putative 0.0039 0.0182 0.0597
Loa Loa (eye worm) hypothetical protein 0.0096 0.0602 0.0677
Plasmodium falciparum cysteine proteinase falcipain 1 0.0141 0.0933 0.5591
Entamoeba histolytica cysteine protease, putative 0.0141 0.0933 0.4638
Trichomonas vaginalis conserved hypothetical protein 0.002 0.004 0.0074
Loa Loa (eye worm) hypothetical protein 0.0073 0.0432 0.0485
Echinococcus multilocularis isocitrate dehydrogenase 0.0023 0.0057 0.0064
Brugia malayi nuclear hormone receptor family member odr-7 0.0044 0.0218 0.0245
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0026 0.0081 0.0151
Brugia malayi Protein kinase domain containing protein 0.013 0.0855 0.0962
Trypanosoma cruzi cysteine peptidase, putative 0.024 0.1669 0.1877
Brugia malayi jmjC domain containing protein 0.0166 0.1118 0.1258
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0094 0.0587 0.066
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Trypanosoma cruzi cysteine peptidase, putative 0.024 0.1669 0.1877
Trichomonas vaginalis DNA polymerase eta, putative 0.0028 0.0097 0.018
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0044 0.0218 0.0246
Loa Loa (eye worm) hypothetical protein 0.0044 0.0218 0.0246
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.013 0.0855 0.0962
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0097 0.0317
Echinococcus granulosus neuropeptide receptor A26 0.0722 0.5239 0.5892
Schistosoma mansoni tyrosine kinase 0.0219 0.1512 0.17
Entamoeba histolytica hypothetical protein 0.0016 0.0011 0.0056
Schistosoma mansoni chromobox protein 0.0051 0.0268 0.0301
Entamoeba histolytica cysteine protease, putative 0.0073 0.0432 0.2144
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0028 0.0097 0.018
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0097 0.0611 0.0687
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0268 0.0498
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0017 0.0013 0.0043
Brugia malayi Patched family protein 0.0017 0.0018 0.0021
Entamoeba histolytica cysteine proteinase, putative 0.0141 0.0933 0.4638
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0017 0.0013 0.0078
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0011 0.0012
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.008 0.0485 0.0871
Brugia malayi beta-lactamase family protein 0.0057 0.0311 0.035
Entamoeba histolytica glycogen phosphorylase, putative 0.0062 0.0351 0.1743
Echinococcus granulosus cathepsin L cysteine protease 0.0141 0.0933 0.1049
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0011 0.0012
Loa Loa (eye worm) mbt repeat family protein 0.008 0.0485 0.0545
Loa Loa (eye worm) hypothetical protein 0.0068 0.0392 0.044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.024 0.1669 0.3105
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0039 0.0182 0.0205
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Onchocerca volvulus 0.0044 0.0218 0.0373
Brugia malayi Patched related family protein 12 0.0017 0.0018 0.0021
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0097 0.0611 0.0687
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0028 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0432 0.0802
Echinococcus granulosus Protein patched homolog 1 0.0123 0.0801 0.09
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.1268 0.9288 1
Plasmodium falciparum serine repeat antigen 5 0.0073 0.0432 0.2584
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0073 0.0432 0.0485
Trypanosoma cruzi cysteine peptidase, putative 0.0141 0.0933 0.105
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0067 0.0388 0.0436
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0094 0.0587 0.0659
Onchocerca volvulus 0.024 0.1669 0.3081
Loa Loa (eye worm) hypothetical protein 0.0044 0.0218 0.0246
Schistosoma mansoni terminal deoxycytidyl transferase 0.0028 0.0097 0.0109
Echinococcus granulosus GPCR family 2 0.0097 0.0611 0.0687
Brugia malayi hypothetical protein 0.0017 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.008 0.0485 0.0545
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Schistosoma mansoni nuclear receptor 0.0044 0.0218 0.0245
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0073 0.0432 0.1415
Schistosoma mansoni glycogen phosphorylase 0.0062 0.0351 0.0394
Onchocerca volvulus 0.074 0.5375 1
Schistosoma mansoni nuclear receptor 0.0044 0.0218 0.0245
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0023 0.0057 0.0064
Entamoeba histolytica cysteine proteinase, putative 0.024 0.1669 0.8295
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0067 0.0388 0.0436
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0426 0.3048 0.567
Loa Loa (eye worm) hypothetical protein 0.021 0.1449 0.163
Echinococcus multilocularis dna polymerase eta 0.0047 0.0235 0.0264
Leishmania major cathepsin L-like protease 0.024 0.1669 0.5475
Echinococcus multilocularis cathepsin L 0.0073 0.0432 0.0485
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0057 0.0311 0.0268
Loa Loa (eye worm) hypothetical protein 0.0091 0.0567 0.0638
Echinococcus granulosus cathepsin l cysteine peptidase 0.024 0.1669 0.1877
Brugia malayi orphan nuclear receptor NR2E1 0.0044 0.0218 0.0245
Echinococcus multilocularis neutral alpha glucosidase AB 0.0026 0.0081 0.0091
Loa Loa (eye worm) fli-1 protein 0.0157 0.1054 0.1185
Schistosoma mansoni cathepsin B (C01 family) 0.0073 0.0432 0.0485
Plasmodium falciparum serine repeat antigen 6 0.0073 0.0432 0.2584
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0017 0.0018 0.002
Chlamydia trachomatis protoporphyrinogen oxidase 0.0096 0.0602 0.6112
Brugia malayi Patched family protein 0.0017 0.0018 0.0021
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0021 0.0044 0.0144
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0023 0.0057 0.0064
Brugia malayi jmjC domain containing protein 0.0064 0.0365 0.041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0432 0.0802
Trypanosoma brucei DNA polymerase IV, putative 0.0028 0.0097 0.0317
Plasmodium falciparum serine repeat antigen 3 0.0073 0.0432 0.2584
Loa Loa (eye worm) steroid hormone receptor 0.0094 0.0587 0.066
Brugia malayi protein C24B5.3 0.0017 0.0018 0.0021
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0118 0.0219
Loa Loa (eye worm) patched family protein 0.0017 0.0018 0.0021
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0067 0.0388 0.0436
Echinococcus granulosus glycogen phosphorylase 0.0144 0.0956 0.1075
Giardia lamblia Cathepsin L precursor 0.0073 0.0432 0.1415
Entamoeba histolytica cysteine protease, putative 0.0141 0.0933 0.4638
Brugia malayi Latrophilin receptor protein 2 0.0097 0.0611 0.0687
Toxoplasma gondii patched family protein 0.0017 0.0018 0.006
Echinococcus granulosus serine:threonine protein kinase PLK1 0.007 0.0405 0.0455
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0017 0.0013 0.0015
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0094 0.0587 0.0659
Entamoeba histolytica cysteine protease, putative 0.0073 0.0432 0.2144
Loa Loa (eye worm) latrophilin receptor protein 2 0.0097 0.0611 0.0688
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0032 0.0128 0.0144
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0096 0.0602 0.3605
Schistosoma mansoni retinoic acid receptor RXR 0.0094 0.0587 0.0659
Brugia malayi Patched family protein 0.0017 0.0018 0.0021
Mycobacterium ulcerans hypothetical protein 0.0057 0.0311 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0432 0.0802
Loa Loa (eye worm) hypothetical protein 0.005 0.0258 0.029
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0016 0.0011 0.0021
Toxoplasma gondii cathepsin B 0.0426 0.3048 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0432 0.0485
Loa Loa (eye worm) hypothetical protein 0.0057 0.0311 0.035
Loa Loa (eye worm) hypothetical protein 0.005 0.0258 0.029
Brugia malayi Cathepsin L-like precursor 0.0172 0.1167 0.1313
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0588 0.0661
Echinococcus granulosus cysteine protease 0.0141 0.0933 0.1049
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0017 0.0012 0.004
Echinococcus multilocularis GA binding protein alpha chain 0.0052 0.0273 0.0307
Brugia malayi hypothetical protein 0.0063 0.0356 0.0401
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0801 0.1489
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0023 0.0057 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0094 0.0587 0.0659
Echinococcus multilocularis cathepsin L 0.0141 0.0933 0.1049
Echinococcus multilocularis epidermal growth factor receptor 0.0407 0.2906 0.3268
Onchocerca volvulus Alhambra homolog 0.0051 0.0265 0.046
Trichomonas vaginalis conserved hypothetical protein 0.002 0.004 0.0074
Entamoeba histolytica cysteine protease, putative 0.0141 0.0933 0.4638
Loa Loa (eye worm) MBCTL1 0.0091 0.0567 0.0638
Brugia malayi beta-lactamase family protein 0.0057 0.0311 0.035
Brugia malayi hypothetical protein 0.0043 0.0207 0.0233
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0405 0.0753
Echinococcus granulosus neutral alpha glucosidase AB 0.0026 0.0081 0.0091
Brugia malayi Cathepsin L-like precursor 0.024 0.1669 0.1877
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Onchocerca volvulus 0.0049 0.0253 0.0438
Brugia malayi Patched family protein 0.0017 0.0018 0.0021
Entamoeba histolytica cysteine protease, putative 0.0073 0.0432 0.2144
Echinococcus granulosus beta LACTamase domain containing family member 0.0057 0.0311 0.035
Giardia lamblia Glycogen phosphorylase 0.0144 0.0956 0.3137
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0094 0.0587 0.0659
Schistosoma mansoni tyrosinase precursor 0.0104 0.0659 0.0741
Schistosoma mansoni hypothetical protein 0.0216 0.1491 0.1677
Brugia malayi cathepsin Z-like cysteine proteinase 0.0073 0.0432 0.0485
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0039 0.0182 0.0597
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0052 0.0273 0.0307
Loa Loa (eye worm) ShTK domain-containing protein 0.0104 0.0659 0.0741
Onchocerca volvulus Cathepsin L homolog 0.024 0.1669 0.3081
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0017 0.0013 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0033 0.0106
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0073 0.0432 0.0485
Plasmodium vivax hypothetical protein, conserved 0.0096 0.0602 0.3605
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0073 0.0432 0.1415
Mycobacterium ulcerans glutaminase 0.0274 0.1924 0.1888
Giardia lamblia Cathepsin B precursor 0.0073 0.0432 0.1415
Entamoeba histolytica glycogen phosphorylase, putative 0.0062 0.0351 0.1743
Loa Loa (eye worm) hypothetical protein 0.0057 0.0311 0.035
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0094 0.0587 0.0659
Mycobacterium ulcerans dehydrogenase 0.0096 0.0602 0.056
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0073 0.0432 0.2584
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.1669 0.3105
Onchocerca volvulus 0.0104 0.0659 0.1195
Echinococcus multilocularis neuropeptide receptor A26 0.0722 0.5239 0.5892
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0028 0.0097 0.0109
Schistosoma mansoni ets-related 0.0157 0.1054 0.1185
Entamoeba histolytica cysteine protease, putative 0.0141 0.0933 0.4638
Echinococcus granulosus serine protein kinase ATM 0.0017 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.1214 0.8892 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0097 0.0317
Mycobacterium tuberculosis Conserved protein 0.0057 0.0311 0.0289
Loa Loa (eye worm) hypothetical protein 0.0073 0.0432 0.0485
Loa Loa (eye worm) hypothetical protein 0.0044 0.0218 0.0246
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Brugia malayi T-complex protein 1, beta subunit 0.0017 0.0013 0.0015
Giardia lamblia Hypothetical protein 0.0073 0.0432 0.1415
Onchocerca volvulus 0.0698 0.5062 0.9415
Echinococcus granulosus epidermal growth factor receptor 0.0407 0.2906 0.3268
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.024 0.1669 0.5475
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0011 0.0064
Plasmodium vivax unspecified product 0.0068 0.0392 0.2345
Brugia malayi Nuclear hormone receptor E75 0.0044 0.0218 0.0245
Toxoplasma gondii isocitrate dehydrogenase 0.0023 0.0057 0.0187
Brugia malayi Patched family protein 0.0017 0.0018 0.0021
Brugia malayi Patched family protein 0.0017 0.0018 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0094 0.0587 0.066
Schistosoma mansoni tyrosine kinase 0.013 0.0855 0.0962
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0073 0.0432 0.0485
Loa Loa (eye worm) hypothetical protein 0.0073 0.0432 0.0485
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Brugia malayi hypothetical protein 0.005 0.0258 0.029
Brugia malayi SWIRM domain containing protein 0.0096 0.0602 0.0677
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0051 0.0265 0.0298
Brugia malayi amine oxidase, flavin-containing family protein 0.0096 0.0602 0.0677
Brugia malayi Cathepsin L-like precursor 0.024 0.1669 0.1877
Brugia malayi beta-lactamase 0.0057 0.0311 0.035
Brugia malayi F/Y-rich N-terminus family protein 0.0035 0.0149 0.0167
Loa Loa (eye worm) hypothetical protein 0.0094 0.0588 0.0661
Loa Loa (eye worm) hypothetical protein 0.0123 0.0801 0.09
Echinococcus granulosus L aminoadipate semialdehyde 0.0074 0.0439 0.0493
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0141 0.0933 0.1736
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0107 0.0685 0.0771
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0017 0.0013 0.0015
Schistosoma mansoni hypothetical protein 0.0077 0.0463 0.0521
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0094 0.0587 0.0659
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0017 0.0013 0.0015
Brugia malayi Patched family protein 0.0017 0.0018 0.0021
Giardia lamblia Kinase, PLK 0.007 0.0405 0.1328
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0021 0.0044 0.5
Brugia malayi Papain family cysteine protease containing protein 0.0141 0.0933 0.1049
Brugia malayi nuclear receptor RXR 0.005 0.0258 0.029
Giardia lamblia Cysteine protease 0.0073 0.0432 0.1415
Brugia malayi Pre-SET motif family protein 0.0094 0.0588 0.0661
Leishmania major alpha glucosidase II subunit, putative 0.0026 0.0081 0.0266
Loa Loa (eye worm) TK/INSR protein kinase 0.013 0.0855 0.0962
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Trypanosoma cruzi UDP-galactopyranose mutase 0.0096 0.0602 0.0677
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0432 0.0802
Giardia lamblia Cathepsin B precursor 0.0073 0.0432 0.1415
Toxoplasma gondii histone lysine-specific demethylase 0.0096 0.0602 0.1974
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0011 0.0012
Leishmania major hypothetical protein, conserved 0.0057 0.0311 0.102
Schistosoma mansoni cpg binding protein 0.0052 0.0274 0.0307
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0019 0.0032 0.0036
Mycobacterium tuberculosis Conserved protein 0.0057 0.0311 0.0289
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0032 0.0035
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0057 0.0311 0.035
Trypanosoma cruzi importin beta-1 subunit, putative 0.0016 0.0011 0.0013
Schistosoma mansoni cathepsin S (C01 family) 0.0073 0.0432 0.0485
Brugia malayi AF-10 protein 0.0017 0.0012 0.0014
Giardia lamblia Cathepsin L precursor 0.0073 0.0432 0.1415
Entamoeba histolytica cysteine protease, putative 0.0141 0.0933 0.4638
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0103 0.065 0.0731
Echinococcus multilocularis cathepsin l cysteine peptidase 0.024 0.1669 0.1877
Leishmania major DNA polymerase eta, putative 0.0027 0.0092 0.0302
Trypanosoma cruzi DNA polymerase eta, putative 0.0047 0.0235 0.0264
Brugia malayi MH2 domain containing protein 0.0196 0.134 0.1506
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0073 0.0432 0.0802
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0011 0.0012
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0068 0.0392 0.044
Trichomonas vaginalis chaperonin, putative 0.0017 0.0013 0.0024
Brugia malayi Common central domain of tyrosinase family protein 0.0104 0.0659 0.0741
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0286 0.2012 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0073 0.0432 0.2144
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0073 0.0432 0.2584
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.1669 0.3105
Brugia malayi Patched family protein 0.0017 0.0018 0.0021
Trypanosoma brucei importin beta-1 subunit, putative 0.002 0.004 0.013
Schistosoma mansoni tyrosine kinase 0.013 0.0855 0.0962
Loa Loa (eye worm) PHD-finger family protein 0.0051 0.0265 0.0298
Mycobacterium tuberculosis Conserved hypothetical protein 0.0028 0.0097 0.0057
Toxoplasma gondii patched family protein 0.0017 0.0018 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0073 0.0432 0.0802
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0023 0.0057 0.0014
Onchocerca volvulus 0.024 0.1669 0.3081
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.007 0.0405 0.1328
Loa Loa (eye worm) glycogen phosphorylase 0.0144 0.0956 0.1076
Trypanosoma cruzi major cysteine proteinase, putative 0.0073 0.0432 0.0485
Echinococcus multilocularis neuropeptide s receptor 0.0722 0.5239 0.5892
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0141 0.0933 0.1049
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0023 0.0057 0.0064
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0019 0.0032 0.0036
Loa Loa (eye worm) hypothetical protein 0.0094 0.0587 0.066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0094 0.0587 0.066
Plasmodium falciparum importin beta, putative 0.002 0.004 0.0237
Leishmania major cathepsin L-like protease 0.024 0.1669 0.5475
Trypanosoma cruzi DNA polymerase kappa, putative 0.0028 0.0097 0.0109
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0097 0.0611 0.0687
Entamoeba histolytica hypothetical protein 0.0073 0.0432 0.2144
Giardia lamblia Hypothetical protein 0.0073 0.0432 0.1415
Brugia malayi Nuclear hormone receptor-like 1 0.005 0.0258 0.029
Loa Loa (eye worm) RNA binding protein 0.0249 0.1737 0.1954
Echinococcus granulosus cathepsin L 0.0073 0.0432 0.0485
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0405 0.0753
Onchocerca volvulus 0.024 0.1669 0.3081
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0044 0.0144
Brugia malayi Cathepsin L-like precursor 0.0068 0.0392 0.044
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0116 0.0753 0.0846
Echinococcus multilocularis snurportin 1 0.0216 0.1491 0.1677
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0094 0.0587 0.0659
Loa Loa (eye worm) hypothetical protein 0.0172 0.1167 0.1313
Trypanosoma brucei DNA polymerase IV, putative 0.0028 0.0097 0.0317
Plasmodium falciparum serine repeat antigen 7 0.0073 0.0432 0.2584
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.024 0.1669 0.3105
Entamoeba histolytica glycogenphosphorylase, putative 0.0062 0.0351 0.1743
Echinococcus granulosus phd:f box containing protein 0.0016 0.0011 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0051 0.0265 0.1586
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0432 0.0802
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0011 0.0012
Onchocerca volvulus 0.0104 0.0659 0.1195
Entamoeba histolytica serine/threonine protein kinase, putative 0.007 0.0405 0.2013
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Brugia malayi RNA binding protein 0.0249 0.1737 0.1954
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0141 0.0933 0.105
Schistosoma mansoni hypothetical protein 0.0118 0.0768 0.0863
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0405 0.0753
Brugia malayi Patched family protein 0.0017 0.0018 0.0021
Plasmodium falciparum cysteine proteinase falcipain 2b 0.024 0.1669 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0051 0.0265 0.0869
Giardia lamblia TCP-1 chaperonin subunit beta 0.0017 0.0013 0.0043
Brugia malayi cathepsin F-like cysteine proteinase 0.0073 0.0432 0.0485
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0005 0.0006
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0363 0.2581 0.2745
Onchocerca volvulus 0.024 0.1669 0.3081
Echinococcus multilocularis Niemann Pick C1 protein 0.0286 0.2012 0.2263
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.024 0.1669 0.5475
Plasmodium falciparum cysteine proteinase falcipain 3 0.024 0.1669 1
Brugia malayi Patched related family protein 4 0.0017 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0172 0.1167 0.1313
Echinococcus multilocularis 0.0126 0.0823 0.0925
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0023 0.0057 0.0064
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0426 0.3048 0.3428
Schistosoma mansoni nuclear hormone receptor 0.0094 0.0587 0.0659
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0073 0.0432 0.2584
Echinococcus granulosus cathepsin b 0.1214 0.8892 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0094 0.0587 0.0659
Schistosoma mansoni glutaminase 0.0274 0.1924 0.2163
Plasmodium falciparum serine repeat antigen 4 0.0073 0.0432 0.2584
Onchocerca volvulus 0.0172 0.1167 0.2145
Echinococcus multilocularis mitogen activated protein kinase 3 0.0039 0.0182 0.0205
Plasmodium vivax ataxin-2 like protein, putative 0.0043 0.0207 0.1241
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0097 0.0317
Loa Loa (eye worm) hypothetical protein 0.024 0.1669 0.1877
Schistosoma mansoni RAR-like nuclear receptor 0.0094 0.0587 0.0659
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.024 0.1669 0.3105
Schistosoma mansoni sex comb on midleg homolog 0.008 0.0485 0.0545
Onchocerca volvulus 0.0096 0.0602 0.1089
Brugia malayi hypothetical protein 0.0017 0.0018 0.0021
Brugia malayi T-complex protein 1, beta subunit 0.0017 0.0013 0.0015
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0074 0.0439 0.0493
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0073 0.0432 0.1415
Schistosoma mansoni tar DNA-binding protein 0.0249 0.1737 0.1954
Plasmodium falciparum cysteine proteinase falcipain 2a 0.024 0.1669 1
Brugia malayi jmjC domain containing protein 0.0016 0.0011 0.0012
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0039 0.0182 0.0205
Brugia malayi nuclear receptor NHR-67 0.0044 0.0218 0.0245
Brugia malayi photoreceptor-specific nuclear receptor 0.0094 0.0587 0.0659
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0044 0.0218 0.0373
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0044 0.0218 0.0246
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0017 0.0012 0.004
Echinococcus multilocularis epidermal growth factor receptor 0.0219 0.1512 0.17
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0067 0.0388 0.0436
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0039 0.0182 0.0597
Brugia malayi conserved hypotetical protein 0.0044 0.0218 0.0245
Echinococcus granulosus nuclear receptor nhr 48 0.0044 0.0218 0.0245
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0104 0.0659 0.0741
Leishmania major hypothetical protein, conserved 0.0016 0.0011 0.0035
Entamoeba histolytica cysteine proteinase, putative 0.0172 0.1167 0.5801
Brugia malayi Niemann-Pick C1 protein precursor 0.0286 0.2012 0.2263
Echinococcus multilocularis tar DNA binding protein 0.0249 0.1737 0.1954
Trypanosoma cruzi DNA polymerase kappa, putative 0.0028 0.0097 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0432 0.0802
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0032 0.0035
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0035 0.0151 0.017
Schistosoma mansoni thyroid hormone receptor 0.0094 0.0587 0.0659
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0308 0.2171 0.2441
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0432 0.0802
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.024 0.1669 0.5475
Brugia malayi hypothetical protein 0.0017 0.0018 0.0021
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0023 0.0057 0.0341
Brugia malayi Cathepsin L-like cysteine proteinase 0.0172 0.1167 0.1313
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0017 0.0013 0.0065
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0017 0.0018 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0141 0.0933 0.3061
Loa Loa (eye worm) hypothetical protein 0.0172 0.1167 0.1313
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0081 0.0091
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0057 0.0311 0.035
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0034 0.0063
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0021 0.0044 0.0264
Echinococcus multilocularis Glycosyl transferase, family 35 0.0144 0.0956 0.1075
Leishmania major cathepsin L-like protease 0.024 0.1669 0.5475
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Brugia malayi carbohydrate phosphorylase 0.0144 0.0956 0.1075
Schistosoma mansoni amine oxidase 0.0096 0.0602 0.0677
Giardia lamblia PHD finger protein 15 0.0051 0.0265 0.0869
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0081 0.0151
Schistosoma mansoni nuclear hormone receptor 0.0044 0.0218 0.0245
Echinococcus multilocularis lysosomal alpha glucosidase 0.0116 0.0753 0.0846
Plasmodium falciparum ataxin-2 like protein, putative 0.0043 0.0207 0.1241
Schistosoma mansoni tyrosine kinase 0.0216 0.1492 0.1678
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0026 0.0081 0.0403
Schistosoma mansoni hypothetical protein 0.0491 0.3527 0.3966
Brugia malayi Patched family protein 0.0017 0.0018 0.0021
Echinococcus multilocularis FTZ F1 alpha 0.0094 0.0587 0.0659
Entamoeba histolytica hypothetical protein 0.0021 0.0044 0.0219
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0141 0.0933 0.1049
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0067 0.0388 0.0436
Brugia malayi Papain family cysteine protease containing protein 0.0073 0.0432 0.0485
Leishmania major phosphopantetheinyl transferase-like protein 0.0021 0.0044 0.0144
Mycobacterium ulcerans DNA polymerase IV 0.0028 0.0097 0.0053
Brugia malayi Patched family protein 0.0017 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0057 0.0311 0.035
Loa Loa (eye worm) patched family protein 0.0017 0.0018 0.0021
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0011 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0094 0.0587 0.0659
Brugia malayi cathepsin L-like precursor 0.0172 0.1167 0.1313
Echinococcus multilocularis insulin receptor 0.013 0.0855 0.0962
Schistosoma mansoni tyrosine kinase 0.0216 0.1492 0.1678
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0081 0.0091
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0034 0.0063
Schistosoma mansoni hypothetical protein 0.0019 0.0032 0.0036
Plasmodium vivax JmjC domain containing protein 0.0016 0.0011 0.0064
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0031 0.0118 0.0185
Brugia malayi Glycosyl hydrolases family 31 protein 0.0026 0.0081 0.0091
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Echinococcus multilocularis polycomb protein SCMH1 0.008 0.0485 0.0545
Schistosoma mansoni hypothetical protein 0.0097 0.0611 0.0687
Loa Loa (eye worm) hypothetical protein 0.0022 0.0056 0.0063
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0011 0.0035
Brugia malayi Nuclear hormone receptor-like 1 0.0094 0.0587 0.0659
Leishmania major cathepsin L-like protease 0.024 0.1669 0.5475
Schistosoma mansoni hypothetical protein 0.0097 0.0611 0.0687
Trypanosoma brucei glucosidase, putative 0.0026 0.0081 0.0266
Brugia malayi fibroinase precursor 0.0073 0.0432 0.0485
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0081 0.0151
Brugia malayi Papain family cysteine protease containing protein 0.0073 0.0432 0.0485
Echinococcus granulosus cathepsin L 0.0141 0.0933 0.1049
Echinococcus granulosus thyroid hormone receptor alpha 0.0044 0.0218 0.0245
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0077 0.0463 0.0521
Plasmodium vivax hypothetical protein, conserved 0.002 0.0035 0.0206
Loa Loa (eye worm) hypothetical protein 0.0173 0.1171 0.1317
Trypanosoma brucei unspecified product 0.0019 0.0033 0.0106
Brugia malayi cathepsin L precursor 0.0073 0.0432 0.0485
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0028 0.0097 0.0109
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0172 0.1167 0.1313
Trypanosoma cruzi cruzipain precursor, putative 0.024 0.1669 0.1877
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0096 0.0602 0.0677
Brugia malayi Cathepsin L-like precursor 0.0172 0.1167 0.1313
Brugia malayi TAR-binding protein 0.0249 0.1737 0.1954
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0588 0.0661
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0588 0.0661
Brugia malayi Furin-like cysteine rich region family protein 0.0407 0.2906 0.3268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.1669 0.3105
Onchocerca volvulus 0.0104 0.0659 0.1195
Echinococcus multilocularis cathepsin b 0.1214 0.8892 1
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0017 0.0013 0.0015
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0249 0.1737 0.1954
Toxoplasma gondii PHD-finger domain-containing protein 0.0051 0.0265 0.0869
Brugia malayi ecdysteroid receptor 0.0094 0.0587 0.0659
Brugia malayi protein C24B5.3 0.0017 0.0018 0.0021
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0023 0.0057 0.0187
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0219 0.1512 0.17
Plasmodium falciparum T-complex protein 1 subunit beta 0.0017 0.0013 0.0078
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0081 0.0151
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0017 0.0013 0.0015
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0026 0.0081 0.0403
Plasmodium falciparum phd finger protein, putative 0.0051 0.0265 0.1586
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0034 0.0063
Loa Loa (eye worm) hypothetical protein 0.005 0.0258 0.029
Plasmodium vivax vivapain-2 0.024 0.1669 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0044 0.0218 0.0245
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.024 0.1669 0.5475
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0172 0.1167 0.2171
Trypanosoma brucei DNA polymerase IV, putative 0.0028 0.0097 0.0317
Schistosoma mansoni steroid hormone receptor ad4bp 0.0094 0.0587 0.0659
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0073 0.0432 0.0485
Mycobacterium tuberculosis Probable lipase LipD 0.0057 0.0311 0.0289
Loa Loa (eye worm) CXXC zinc finger family protein 0.0049 0.0253 0.0284
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0028 0.0097 0.0317
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0011 0.0012
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0017 0.0018 0.002
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0067 0.0388 0.0436
Loa Loa (eye worm) hypothetical protein 0.0057 0.0311 0.035
Echinococcus multilocularis protoporphyrinogen oxidase 0.0096 0.0602 0.0677
Giardia lamblia Cathepsin L-like protease 0.0073 0.0432 0.1415
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0094 0.0587 0.0659
Schistosoma mansoni hypothetical protein 0.0118 0.0768 0.0863
Brugia malayi steroid hormone receptor 0.0094 0.0587 0.0659
Loa Loa (eye worm) hypothetical protein 0.0044 0.0218 0.0246
Toxoplasma gondii patched family protein 0.0017 0.0018 0.006
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0365 0.041
Trichomonas vaginalis D-aminoacylase, putative 0.0057 0.0311 0.0578
Loa Loa (eye worm) hypothetical protein 0.0096 0.0602 0.0677
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0094 0.0587 0.0659
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0104 0.0659 0.0741
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.1669 0.3105
Entamoeba histolytica cysteine proteinase 2 0.0141 0.0933 0.4638
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0021 0.0044 0.0144
Loa Loa (eye worm) hypothetical protein 0.0044 0.0218 0.0246
Loa Loa (eye worm) ShTK domain-containing protein 0.0104 0.0659 0.0741
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0027 0.0092 0.0302
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0094 0.0587 0.066
Brugia malayi hypothetical protein 0.0698 0.5062 0.5693
Schistosoma mansoni hypothetical protein 0.0758 0.5506 0.6192
Brugia malayi Nuclear hormone receptor-like 1 0.005 0.0258 0.029
Brugia malayi Fli-1 protein 0.0157 0.1054 0.1185
Echinococcus granulosus cathepsin l1 0.024 0.1669 0.1877
Toxoplasma gondii cathepsin CPC2 0.0073 0.0432 0.1415
Loa Loa (eye worm) fibroinase 0.024 0.1669 0.1877
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.005 0.0258 0.029
Echinococcus granulosus histone acetyltransferase MYST2 0.0091 0.0567 0.0638
Giardia lamblia Cathepsin B precursor 0.0426 0.3048 1
Entamoeba histolytica cysteine protease, putative 0.0073 0.0432 0.2144
Entamoeba histolytica cysteine protease, putative 0.0141 0.0933 0.4638
Entamoeba histolytica cysteine protease, putative 0.0141 0.0933 0.4638
Schistosoma mansoni retinoid-x-receptor (RXR) 0.005 0.0258 0.029
Loa Loa (eye worm) hypothetical protein 0.0094 0.0587 0.066
Entamoeba histolytica hypothetical protein 0.0077 0.0463 0.2303
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0094 0.0587 0.0659
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.005 0.0258 0.029
Loa Loa (eye worm) hypothetical protein 0.0044 0.0218 0.0245
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0011 0.0012
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0023 0.0057 0.0064
Brugia malayi hypothetical protein 0.0028 0.0095 0.0106
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0044 0.0218 0.0245
Loa Loa (eye worm) ctsf protein 0.024 0.1669 0.1877
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0118 0.0219
Trypanosoma cruzi cysteine proteinase, putative 0.0141 0.0933 0.105
Trypanosoma brucei importin beta-1 subunit, putative 0.002 0.004 0.013
Brugia malayi Steroid receptor seven-up type 2 0.0094 0.0587 0.0659
Onchocerca volvulus Protein ultraspiracle homolog 0.0094 0.0587 0.106
Schistosoma mansoni importin beta-1 0.002 0.004 0.0045
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0661 0.4787 0.5384
Trichomonas vaginalis penicillin-binding protein, putative 0.0057 0.0311 0.0578
Loa Loa (eye worm) hypothetical protein 0.005 0.0258 0.029
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0044 0.0218 0.0245
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0094 0.0587 0.0659
Trypanosoma cruzi polo-like protein kinase, putative 0.007 0.0405 0.0456
Loa Loa (eye worm) hypothetical protein 0.0094 0.0587 0.066
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.024 0.1669 0.5475
Brugia malayi Patched family protein 0.0017 0.0018 0.0021
Mycobacterium ulcerans beta-lactamase 0.0057 0.0311 0.0268
Brugia malayi RNA recognition motif domain containing protein 0.0249 0.1737 0.1954
Trypanosoma cruzi PAB1-binding protein , putative 0.0043 0.0207 0.0233
Trypanosoma brucei cysteine peptidase C (CPC) 0.0426 0.3048 1
Trypanosoma brucei DNA polymerase eta, putative 0.0047 0.0235 0.077
Plasmodium vivax unspecified product 0.0141 0.0933 0.5591
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0011 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0097 0.0317
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0094 0.0587 0.0659
Loa Loa (eye worm) hypothetical protein 0.0073 0.0432 0.0485
Schistosoma mansoni sex comb on midleg homolog 0.008 0.0485 0.0545
Onchocerca volvulus 0.0057 0.0311 0.0546
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0073 0.0432 0.0802
Brugia malayi Calcitonin receptor-like protein seb-1 0.0308 0.2171 0.2441
Schistosoma mansoni serine/threonine protein kinase 0.007 0.0405 0.0455
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0044 0.0218 0.0245
Trypanosoma cruzi cysteine proteinase, putative 0.0141 0.0933 0.105
Loa Loa (eye worm) hypothetical protein 0.0097 0.0611 0.0688
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0011 0.0012
Entamoeba histolytica glycogen phosphorylase, putative 0.0144 0.0956 0.4753
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0094 0.0588 0.1929
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1214 0.8892 1
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.007 0.0405 0.0455
Trichomonas vaginalis sucrase-isomaltase, putative 0.0026 0.0081 0.0151
Echinococcus multilocularis cathepsin L cysteine protease 0.024 0.1669 0.1877
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0432 0.0802
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0097 0.0611 0.0687
Echinococcus granulosus mitogen activated protein kinase 0.0039 0.0182 0.0205
Loa Loa (eye worm) hypothetical protein 0.0068 0.0392 0.044
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0044 0.0218 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0073 0.0432 0.0802
Echinococcus granulosus tar DNA binding protein 0.0249 0.1737 0.1954
Schistosoma mansoni patched 1 0.0123 0.0801 0.09
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0096 0.0602 0.3605
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0094 0.0587 0.0659
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0073 0.0432 0.0485
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.065 0.471 0.5297
Echinococcus granulosus jumonji domain containing protein 0.007 0.0412 0.0463
Loa Loa (eye worm) hypothetical protein 0.0094 0.0587 0.066
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0073 0.0432 0.2144
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0073 0.0432 0.0485
Toxoplasma gondii hypothetical protein 0.0017 0.0018 0.006
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Trichomonas vaginalis penicillin-binding protein, putative 0.0057 0.0311 0.0578
Loa Loa (eye worm) glutaminase 0.0274 0.1924 0.2163
Leishmania major importin beta-1 subunit, putative 0.0016 0.0011 0.0037
Entamoeba histolytica hypothetical protein 0.0077 0.0463 0.2303
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0182 0.0339
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0123 0.0801 0.09
Plasmodium falciparum serine repeat antigen 9 0.0073 0.0432 0.2584
Loa Loa (eye worm) hypothetical protein 0.0096 0.0602 0.0677
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0028 0.0031
Loa Loa (eye worm) hypothetical protein 0.0096 0.0602 0.0677
Schistosoma mansoni tyrosine kinase 0.0219 0.1512 0.17
Loa Loa (eye worm) DR-78 0.0044 0.0218 0.0246
Echinococcus multilocularis glycogen phosphorylase 0.0144 0.0956 0.1075
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.002 0.0035 0.0206
Toxoplasma gondii patched family protein 0.0017 0.0018 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0097 0.0317
Onchocerca volvulus 0.024 0.1669 0.3081
Echinococcus multilocularis thyroid hormone receptor alpha 0.0094 0.0587 0.0659
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0097 0.0317
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0073 0.0432 0.0485
Entamoeba histolytica cysteine proteinase, putative 0.0141 0.0933 0.4638
Onchocerca volvulus Glycogen phosphorylase homolog 0.0144 0.0956 0.1751
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0182 0.0339
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0555 0.0624
Schistosoma mansoni nuclear receptor nhr-48 0.0044 0.0218 0.0245
Giardia lamblia Cathepsin B precursor 0.0426 0.3048 1
Brugia malayi Ets-domain containing protein 0.0052 0.0273 0.0307
Brugia malayi Papain family cysteine protease containing protein 0.0073 0.0432 0.0485
Loa Loa (eye worm) papain family cysteine protease containing protein 0.024 0.1669 0.1877
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0073 0.0432 0.0485
Brugia malayi Cathepsin L-like precursor 0.024 0.1669 0.1877
Echinococcus multilocularis dna polymerase kappa 0.0028 0.0097 0.0109
Echinococcus granulosus polycomb protein SCMH1 0.008 0.0485 0.0545
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Brugia malayi CHE-14 protein 0.0123 0.0801 0.09
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0094 0.0587 0.0659
Plasmodium vivax vivapain-3 0.0141 0.0933 0.5591
Entamoeba histolytica cysteine protease, putative 0.0141 0.0933 0.4638
Mycobacterium ulcerans lipase LipD 0.0057 0.0311 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.024 0.1669 0.3105
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.1364 1 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Onchocerca volvulus 0.0035 0.0151 0.0248
Schistosoma mansoni glycogen phosphorylase 0.0144 0.0956 0.1075
Leishmania major DNA polymerase kappa, putative 0.0028 0.0097 0.0317
Giardia lamblia Cathepsin L precursor 0.0073 0.0432 0.1415
Schistosoma mansoni hypothetical protein 0.0097 0.0611 0.0687
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.007 0.0405 0.0456
Plasmodium falciparum ataxin-2 like protein, putative 0.0043 0.0207 0.1241
Brugia malayi RNA, U transporter 1 0.0058 0.0316 0.0356
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0182 0.0339
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Brugia malayi Pre-SET motif family protein 0.065 0.471 0.5297
Entamoeba histolytica deoxycytidyl transferase, putative 0.0028 0.0097 0.048
Brugia malayi Nuclear hormone receptor E75 0.0044 0.0218 0.0245
Echinococcus granulosus glycogen phosphorylase 0.0144 0.0956 0.1075
Echinococcus granulosus dna polymerase kappa 0.0028 0.0097 0.0109
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.024 0.1669 0.3105
Onchocerca volvulus Serine\/threonine kinase homolog 0.007 0.0405 0.0722
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0011 0.0035
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0057 0.0311 0.0289
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0432 0.0802
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0073 0.0432 0.2584
Entamoeba histolytica cysteine protease, putative 0.0141 0.0933 0.4638
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0044 0.0218 0.0245
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0034 0.0063
Toxoplasma gondii ABC1 family protein 0.0057 0.0311 0.102
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0018 0.002
Loa Loa (eye worm) glutaminase 2 0.0274 0.1924 0.2163
Schistosoma mansoni tyrosine kinase 0.0407 0.2906 0.3268
Loa Loa (eye worm) hypothetical protein 0.0063 0.0356 0.0401
Leishmania major cathepsin L-like protease 0.024 0.1669 0.5475
Schistosoma mansoni tar DNA-binding protein 0.0249 0.1737 0.1954
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0102 0.0189
Entamoeba histolytica cysteine protease, putative 0.0073 0.0432 0.2144
Leishmania major DNA polymerase eta, putative 0.0047 0.0235 0.077
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0094 0.0587 0.0659
Trichomonas vaginalis alpha-glucosidase, putative 0.0026 0.0081 0.0151
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0141 0.0933 0.3061
Brugia malayi hypothetical protein 0.0096 0.0602 0.0677
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0073 0.0432 0.0485
Entamoeba histolytica cysteine proteinase 1, putative 0.0141 0.0933 0.4638
Echinococcus granulosus PHD finger protein rhinoceros 0.0051 0.0265 0.0298
Echinococcus multilocularis expressed conserved protein 0.0269 0.1883 0.2118
Schistosoma mansoni hypothetical protein 0.0118 0.0768 0.0863
Leishmania major UDP-galactopyranose mutase 0.0096 0.0602 0.1974
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0311 0.035
Entamoeba histolytica cysteine protease, putative 0.0141 0.0933 0.4638
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0023 0.0057 0.0187
Entamoeba histolytica cysteine proteinase, putative 0.024 0.1669 0.8295
Trypanosoma brucei hypothetical protein, conserved 0.0057 0.0311 0.102
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.024 0.1669 0.3105
Loa Loa (eye worm) hypothetical protein 0.0151 0.1005 0.1131
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0094 0.0587 0.0659
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0426 0.3048 0.3428
Schistosoma mansoni hypothetical protein 0.0758 0.5506 0.6192
Loa Loa (eye worm) hypothetical protein 0.0087 0.0533 0.0599
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0023 0.0057 0.0341
Echinococcus granulosus Nuclear hormone receptor HR96 0.0044 0.0218 0.0245
Trypanosoma cruzi cysteine peptidase, putative 0.024 0.1669 0.1877
Echinococcus multilocularis cysteine protease 0.024 0.1669 0.1877
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.024 0.1669 0.5475
Echinococcus granulosus Glycosyl transferase family 35 0.0144 0.0956 0.1075
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0026 0.0081 0.0151
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0011 0.0035
Loa Loa (eye worm) hypothetical protein 0.0047 0.0235 0.0264
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.024 0.1669 0.1877
Schistosoma mansoni kinase 0.0036 0.0153 0.0172
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0039 0.0182 0.0205
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0073 0.0432 0.2584
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0432 0.0802
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0097 0.0317
Plasmodium vivax hypothetical protein, conserved 0.0057 0.0311 0.1863
Onchocerca volvulus 0.0074 0.0439 0.0785
Plasmodium falciparum serine repeat antigen 2 0.0073 0.0432 0.2584
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0034 0.0063
Loa Loa (eye worm) hypothetical protein 0.0094 0.0587 0.066
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0067 0.0388 0.0436
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0028 0.0031
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0026 0.0081 0.0091
Entamoeba histolytica hypothetical protein 0.0017 0.0018 0.0088
Plasmodium vivax hypothetical protein, conserved 0.0096 0.0602 0.3605
Echinococcus multilocularis ecdysone induced protein 78C 0.0094 0.0587 0.0659
Entamoeba histolytica cysteine proteinase, putative 0.0141 0.0933 0.4638
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0104 0.0659 0.0741
Entamoeba histolytica cysteine protease, putative 0.0141 0.0933 0.4638
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0392 0.044
Trypanosoma cruzi DNA polymerase kappa, putative 0.0028 0.0097 0.0109
Trichomonas vaginalis maltase-glucoamylase, putative 0.0026 0.0081 0.0151
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0182 0.0205
Trypanosoma brucei PAB1-binding protein , putative 0.0043 0.0207 0.068
Loa Loa (eye worm) beta-lactamase 0.0057 0.0311 0.035
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.005 0.0258 0.029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.024 0.1669 0.3105
Onchocerca volvulus 0.0057 0.0311 0.0546
Brugia malayi Patched family protein 0.0017 0.0018 0.0021
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0094 0.0587 0.0659
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.024 0.1669 0.3105
Trichomonas vaginalis D-aminoacylase, putative 0.0057 0.0311 0.0578
Onchocerca volvulus Bile acid receptor homolog 0.0094 0.0587 0.106
Loa Loa (eye worm) hypothetical protein 0.0044 0.0218 0.0246
Plasmodium vivax SET domain protein, putative 0.0094 0.0588 0.3522
Loa Loa (eye worm) hypothetical protein 0.0096 0.0602 0.0677
Echinococcus multilocularis SAM and MBT domain containing protein 0.008 0.0485 0.0545
Entamoeba histolytica cysteine proteinase, putative 0.0141 0.0933 0.4638
Echinococcus multilocularis survival motor neuron protein 1 0.0173 0.1171 0.1317
Echinococcus granulosus FTZ F1 alpha 0.0094 0.0587 0.0659
Schistosoma mansoni alpha glucosidase 0.0026 0.0081 0.0091
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.1669 0.3105
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0073 0.0432 0.2584
Brugia malayi Isocitrate dehydrogenase 0.0023 0.0057 0.0064
Onchocerca volvulus 0.0044 0.0218 0.0373
Echinococcus multilocularis cysteine protease 0.024 0.1669 0.1877
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0044 0.0218 0.0245
Schistosoma mansoni amine oxidase 0.0096 0.0602 0.0677
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0097 0.0611 0.0687
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0094 0.0587 0.0659
Trypanosoma brucei unspecified product 0.0028 0.0097 0.0317
Brugia malayi hypothetical protein 0.0044 0.0218 0.0245
Brugia malayi CXXC zinc finger family protein 0.0049 0.0253 0.0284
Schistosoma mansoni nuclear hormone receptor 0.0044 0.0218 0.0245
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0096 0.0602 0.3605
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0021
Entamoeba histolytica cysteine protease, putative 0.024 0.1669 0.8295
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0141 0.0933 0.1049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.024 0.1669 0.5475
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0094 0.0587 0.066
Brugia malayi Cathepsin L-like precursor 0.024 0.1669 0.1877
Giardia lamblia Cathepsin B precursor 0.0073 0.0432 0.1415
Echinococcus multilocularis Niemann Pick C1 protein 0.0409 0.2923 0.3287
Trichomonas vaginalis importin beta-1, putative 0.0016 0.0011 0.0021
Schistosoma mansoni hypothetical protein 0.0118 0.0768 0.0863
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0045
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0011 0.0012
Brugia malayi Importin beta-1 subunit 0.002 0.004 0.0045
Brugia malayi nuclear hormone receptor 0.0044 0.0218 0.0245
Brugia malayi nuclear hormone receptor 0.0094 0.0587 0.0659
Trypanosoma cruzi cysteine peptidase, putative 0.024 0.1669 0.1877
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1214 0.8892 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0044 0.0218 0.0246
Schistosoma mansoni zinc finger protein 0.0044 0.0218 0.0245
Echinococcus multilocularis PHD finger protein rhinoceros 0.0051 0.0265 0.0298
Brugia malayi nuclear receptor NHR-88 0.0044 0.0218 0.0245
Loa Loa (eye worm) hypothetical protein 0.0044 0.0218 0.0246
Echinococcus multilocularis beta LACTamase domain containing family member 0.0057 0.0311 0.035
Schistosoma mansoni thyroid hormone receptor 0.0094 0.0587 0.0659
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.1669 0.3105
Loa Loa (eye worm) MH2 domain-containing protein 0.0196 0.134 0.1506
Brugia malayi Patched family protein 0.0017 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0073 0.0432 0.0485
Trichomonas vaginalis glycogen phosphorylase, putative 0.0144 0.0956 0.1779
Brugia malayi Patched protein homolog 1 0.0017 0.0018 0.0021
Echinococcus granulosus mitogen activated protein kinase 3 0.0039 0.0182 0.0205
Brugia malayi nuclear hormone receptor family member nhr-6 0.0044 0.0218 0.0245
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0067 0.0388 0.0436
Loa Loa (eye worm) hypothetical protein 0.0094 0.0587 0.066
Echinococcus granulosus importin subunit beta 1 0.002 0.004 0.0045
Trypanosoma cruzi polo-like protein kinase, putative 0.007 0.0405 0.0456
Giardia lamblia Cathepsin L-like protease 0.0073 0.0432 0.1415
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0073 0.0432 0.0802
Loa Loa (eye worm) hypothetical protein 0.0057 0.0311 0.035
Echinococcus multilocularis cathepsin l cysteine peptidase 0.024 0.1669 0.1877
Brugia malayi isocitrate dehydrogenase 0.0023 0.0057 0.0064
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0365 0.041
Echinococcus granulosus SAM and MBT domain containing protein 0.008 0.0485 0.0545
Entamoeba histolytica hypothetical protein 0.0077 0.0463 0.2303
Loa Loa (eye worm) cysteine protease 0.024 0.1669 0.1877
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0067 0.0388 0.0436
Schistosoma mansoni cathepsin F (C01 family) 0.024 0.1669 0.1877
Loa Loa (eye worm) TK/EGFR protein kinase 0.0407 0.2906 0.3268
Brugia malayi hypothetical protein 0.0077 0.0463 0.0521
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0073 0.0432 0.2584
Onchocerca volvulus 0.0103 0.065 0.1179
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.024 0.1669 0.5475
Echinococcus multilocularis chromobox protein 1 0.0051 0.0268 0.0301
Brugia malayi mbt repeat family protein 0.008 0.0485 0.0545
Echinococcus multilocularis chromobox protein 1 0.0051 0.0268 0.0301
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0216 0.1491 0.1677
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0094 0.0587 0.066
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0094 0.0587 0.0659
Echinococcus multilocularis histone acetyltransferase MYST2 0.0091 0.0567 0.0638
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0039 0.0182 0.0597
Loa Loa (eye worm) heterochromatin protein 1 0.0051 0.0268 0.0301
Echinococcus multilocularis GPCR, family 2 0.0097 0.0611 0.0687
Echinococcus multilocularis serine protein kinase ATM 0.0017 0.0018 0.002
Echinococcus granulosus chromobox protein 1 0.0051 0.0268 0.0301
Echinococcus granulosus lysine specific histone demethylase 1A 0.0096 0.0602 0.0677
Leishmania major cathepsin L-like protease 0.024 0.1669 0.5475
Entamoeba histolytica cysteine protease, putative 0.0073 0.0432 0.2144
Giardia lamblia Cysteine protease 0.0073 0.0432 0.1415
Schistosoma mansoni hypothetical protein 0.0097 0.0611 0.0687
Giardia lamblia Cathepsin B precursor 0.0073 0.0432 0.1415
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0104 0.0659 0.0741
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0062 0.0351 0.0308
Loa Loa (eye worm) hypothetical protein 0.0043 0.0207 0.0233
Brugia malayi mbt repeat family protein 0.008 0.0485 0.0545
Schistosoma mansoni transcription factor LCR-F1 0.0077 0.0463 0.0521
Echinococcus multilocularis glycogen phosphorylase 0.0144 0.0956 0.1075
Onchocerca volvulus Cathepsin F homolog 0.024 0.1669 0.3081
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0039 0.0182 0.0205
Trypanosoma cruzi UDP-galactopyranose mutase 0.0096 0.0602 0.0677
Loa Loa (eye worm) hypothetical protein 0.0063 0.0356 0.0401
Loa Loa (eye worm) hypothetical protein 0.0044 0.0218 0.0246
Trypanosoma cruzi DNA polymerase kappa, putative 0.0028 0.0097 0.0109
Loa Loa (eye worm) hypothetical protein 0.0051 0.0265 0.0298
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0091 0.0567 0.0638
Plasmodium vivax serine-repeat antigen (SERA) 0.0073 0.0432 0.2584
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0432 0.0802
Toxoplasma gondii preprocathepsin c precursor, putative 0.0073 0.0432 0.1415
Echinococcus granulosus survival motor neuron protein 1 0.0173 0.1171 0.1317
Giardia lamblia Encystation-specific protease 0.0073 0.0432 0.1415
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0405 0.0753
Onchocerca volvulus 0.0022 0.0056 0.007
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0073 0.0432 0.0485
Trichomonas vaginalis set domain proteins, putative 0.074 0.5375 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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