Detailed information for compound 91619

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 296.327 | Formula: C15H16N6O
  • H donors: 1 H acceptors: 4 LogP: 1.88 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=CNc1cccc(c1)Cn1cnc2c1ncnc2N(C)C
  • InChi: 1S/C15H16N6O/c1-20(2)14-13-15(17-8-16-14)21(9-18-13)7-11-4-3-5-12(6-11)19-10-22/h3-6,8-10H,7H2,1-2H3,(H,19,22)
  • InChiKey: BDYDHEGERGDCLK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus GABA-A receptor; anion channel Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 447 aa 25.7 %
Brugia malayi Cation transporter family protein GABA-A receptor; anion channel   467 aa 453 aa 28.5 %
Onchocerca volvulus Eukaryotic initiation factor 4A-III homolog GABA-A receptor; anion channel   467 aa 453 aa 26.9 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 468 aa 28.6 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 446 aa 29.1 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 494 aa 25.5 %
Onchocerca volvulus Gamma-aminobutyric acid receptor subunit beta homolog GABA-A receptor; anion channel   467 aa 433 aa 34.6 %
Echinococcus multilocularis glycine receptor subunit beta GABA-A receptor; anion channel   467 aa 478 aa 28.7 %
Onchocerca volvulus Large subunit GTPase 1 homolog GABA-A receptor; anion channel   467 aa 496 aa 26.0 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 446 aa 28.0 %
Echinococcus multilocularis glycine receptor subunit alpha 1 GABA-A receptor; anion channel   467 aa 430 aa 32.3 %
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit GABA-A receptor; anion channel   467 aa 379 aa 19.3 %
Echinococcus granulosus glycine receptor subunit beta GABA-A receptor; anion channel   467 aa 439 aa 29.6 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 441 aa 33.8 %
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative GABA-A receptor; anion channel   467 aa 384 aa 19.5 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein GABA-A receptor; anion channel   467 aa 454 aa 29.5 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein GABA-A receptor; anion channel   467 aa 375 aa 21.9 %
Schistosoma mansoni Cys-loop ligand gated ion channel subunit GABA-A receptor; anion channel   467 aa 479 aa 29.2 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 454 aa 30.4 %
Echinococcus granulosus glycine receptor subunit alpha 1 GABA-A receptor; anion channel   467 aa 430 aa 32.3 %
Onchocerca volvulus Acetylcholine receptor subunit alpha-type homolog GABA-A receptor; anion channel   467 aa 418 aa 19.6 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 435 aa 29.7 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 461 aa 27.8 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 434 aa 26.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum replication factor C subunit 1, putative 0.0019 0.0016 0.0014
Schistosoma mansoni histone deacetylase hda2 0.0532 0.1826 0.1826
Leishmania major histone deacetylase, putative 0.0526 0.1804 0.1801
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0121 0.0451
Brugia malayi Bromodomain containing protein 0.0039 0.0087 0.0086
Onchocerca volvulus 0.0039 0.0088 0.0314
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0082 0.0081
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0016 0.0016
Toxoplasma gondii Erv1 / Alr family protein 0.0033 0.0066 0.0142
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0031 0.003
Brugia malayi Matrixin family protein 0.0091 0.0269 0.0268
Echinococcus multilocularis protein dispatched 1 0.0094 0.028 0.028
Schistosoma mansoni hypothetical protein 0.0868 0.3011 0.3011
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0016 0.0067
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0011 0.0043
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Brugia malayi beta-lactamase family protein 0.0071 0.0199 0.0198
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0114 0.0113
Toxoplasma gondii histone deacetylase HDAC5 0.0225 0.0743 0.159
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0088 0.0088
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0023 0.0031 0.0112
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.001 0.001
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0121 0.012
Mycobacterium leprae Probable lipase LipE 0.0071 0.0199 0.5662
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0016 0.0012
Leishmania major histone deacetylase, putative 0.0526 0.1804 0.1801
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.0463 0.0463
Mycobacterium tuberculosis Conserved protein 0.0024 0.0033 0.0169
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.0514 0.0513
Brugia malayi Muscleblind-like protein 0.0146 0.0465 0.0464
Brugia malayi Kringle domain containing protein 0.0033 0.0066 0.0065
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0042 0.0041
Brugia malayi Steroid receptor seven-up type 2 0.0018 0.0011 0.0011
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0038 0.0034
Schistosoma mansoni hypothetical protein 0.0021 0.0023 0.0023
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0018 0.0011 0.0011
Trichomonas vaginalis histone deacetylase, putative 0.0559 0.1924 0.7906
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0087
Echinococcus granulosus Niemann Pick C1 protein 0.0192 0.0626 0.0625
Loa Loa (eye worm) hypothetical protein 0.009 0.0266 0.0265
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0033 0.0066 0.0062
Loa Loa (eye worm) hypothetical protein 0.0071 0.0199 0.0198
Echinococcus granulosus lamin dm0 0.0026 0.0042 0.0041
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0016 0.0012
Echinococcus multilocularis histone deacetylase 6 0.0532 0.1826 0.1826
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0058 0.0152 0.0148
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0016 0.0012
Echinococcus multilocularis nuclear receptor co repressor related (ncor) 0.0277 0.0927 0.0927
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0033 0.0066 0.0294
Leishmania major T-complex protein 1, beta subunit, putative 0.0023 0.0031 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0018 0.0011 0.0011
Loa Loa (eye worm) histone deacetylase 7A 0.0526 0.1804 0.1804
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0011 0.0043
Onchocerca volvulus 0.0026 0.0042 0.0126
Plasmodium vivax histone deacetylase 1, putative 0.0559 0.1924 1
Echinococcus multilocularis musashi 0.0026 0.0042 0.0041
Echinococcus multilocularis lamin 0.0026 0.0042 0.0041
Echinococcus multilocularis nibrin 0.0019 0.0016 0.0016
Mycobacterium ulcerans epoxide hydrolase EphA 0.0327 0.1102 0.597
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0036 0.0035
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0144 0.0144
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0039 0.0088 0.0088
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0157 0.0802
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0023 0.0029 0.0029
Brugia malayi Pax transcription activation domain interacting protein 0.0019 0.0016 0.0016
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0016 0.0063
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0011
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.012 0.012
Schistosoma mansoni hypothetical protein 0.0047 0.0114 0.0114
Schistosoma mansoni chromosome transmission fidelity factor 0.0019 0.0016 0.0016
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0012 0.0012
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0023 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0087 0.0087
Schistosoma mansoni carbonic anhydrase-related 0.1338 0.467 0.467
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0144 0.0144
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.0514 0.0513
Leishmania major hypothetical protein, conserved 0.0033 0.0066 0.0062
Loa Loa (eye worm) hypothetical protein 0.0026 0.0042 0.0041
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.011 0.0338 0.2155
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0048 0.0048
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0018 0.0011 0.0011
Echinococcus multilocularis chromobox protein 1 0.0068 0.0189 0.0188
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0038 0.0034
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0048 0.0048
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0023 0.0031 0.0031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0018 0.0011 0.0011
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0058 0.0152 0.0148
Schistosoma mansoni hypothetical protein 0.1338 0.467 0.467
Schistosoma mansoni chromobox protein 0.0068 0.0189 0.0189
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0016 0.0016
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0074 0.0304
Echinococcus granulosus zinc finger protein 0.0022 0.0025 0.0024
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0177 0.0573 0.0573
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0177 0.0573 0.0573
Echinococcus multilocularis muscleblind protein 1 0.0146 0.0465 0.0464
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0075 0.0309
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0082 0.0082
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0033 0.0066 0.0066
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0012
Schistosoma mansoni topbp1 0.0019 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0039 0.0087 0.0086
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0329 0.1111 0.111
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0065 0.0178 0.0177
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0514 0.0513
Toxoplasma gondii exonuclease III APE 0.0019 0.0016 0.0035
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0074 0.0304
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0146 0.0463 0.0462
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0048 0.02
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0031 0.0027
Plasmodium vivax histone deacetylase 2, putative 0.0526 0.1804 0.9378
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0088 0.0088
Schistosoma mansoni retinoic acid receptor RXR 0.0018 0.0011 0.0011
Echinococcus multilocularis nAChR subunit 0.0023 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0012
Onchocerca volvulus 0.0091 0.0269 0.1062
Echinococcus multilocularis cpg binding protein 0.0032 0.006 0.006
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0148 0.0471 0.0471
Loa Loa (eye worm) hypothetical protein 0.0071 0.0199 0.0198
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0018 0.0011 0.0011
Loa Loa (eye worm) inositol-1 0.0036 0.0075 0.0075
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0088 0.0088
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0016 0.0004
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0085 0.0251 0.025
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0004
Onchocerca volvulus 0.01 0.0303 0.1205
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0048 0.0103
Mycobacterium ulcerans hypothetical protein 0.0039 0.0088 0.0423
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0074 0.0159
Schistosoma mansoni inositol monophosphatase 0.0036 0.0075 0.0075
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0199 0.0199
Echinococcus multilocularis histone deacetylase 7 0.0526 0.1804 0.1804
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0157 0.0157
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.001 0.001
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0148 0.0471 0.0471
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0121 0.012
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0031 0.0445
Leishmania major hypothetical protein, conserved 0.0206 0.0677 0.0674
Trypanosoma cruzi hypothetical protein, conserved 0.0206 0.0677 0.0674
Brugia malayi excitatory GABA receptor EXP-1A 0.0023 0.0029 0.0028
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.1338 0.467 0.467
Echinococcus granulosus RUN 0.0019 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0009
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0114 0.0353 0.0352
Echinococcus granulosus replication factor c subunit 1 0.0019 0.0016 0.0016
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0016 0.0016
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0146 0.0463 0.0462
Brugia malayi SET domain containing protein 0.0015 0.0002 0.0001
Trypanosoma cruzi histone deacetylase, putative 0.0526 0.1804 0.1801
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0031 0.0156
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0016 0.0012
Echinococcus multilocularis chromobox protein 1 0.0068 0.0189 0.0188
Schistosoma mansoni bromodomain containing protein 0.0066 0.0182 0.0182
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0199 0.0198
Echinococcus granulosus potassium voltage gated channel subfamily KQT 0.0065 0.0178 0.0177
Onchocerca volvulus 0.0033 0.0066 0.0225
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0023 0.0029 0.0028
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0036 0.0036
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0017 0.0017
Brugia malayi Protein kinase domain containing protein 0.0033 0.0066 0.0065
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0049 0.0123 0.0119
Echinococcus granulosus histone deacetylase 8 0.0225 0.0743 0.0742
Loa Loa (eye worm) hypothetical protein 0.0427 0.1455 0.1455
Brugia malayi F/Y-rich N-terminus family protein 0.0023 0.003 0.0029
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0199 0.0199
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0016 0.0012
Onchocerca volvulus 0.0023 0.0029 0.0071
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0018 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0868 0.3011 0.3011
Onchocerca volvulus Phospholipase A2 homolog 0.0427 0.1455 0.5963
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0092 0.0274 0.0274
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.0054
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.017 0.017
Brugia malayi Histone deacetylase 1 0.0559 0.1924 0.1923
Schistosoma mansoni lamin 0.0026 0.0042 0.0042
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0038 0.0034
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0011 0.0043
Brugia malayi histone deacetylase 3 (HD3) 0.0559 0.1924 0.1923
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0038 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0011
Echinococcus granulosus sterol regulatory element binding protein 0.0082 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0048 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0125 0.0389 0.0388
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0089 0.0264 0.0264
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0023 0.0029 0.0028
Echinococcus multilocularis citrate lyase subunit beta protein 0.0024 0.0033 0.0032
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0157 0.0153
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0011 0.0043
Loa Loa (eye worm) hypothetical protein 0.0085 0.0251 0.025
Echinococcus multilocularis thyroid hormone receptor alpha 0.0018 0.0011 0.0011
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0075 0.0195
Brugia malayi Trypsin-like protease protein 5 0.0039 0.0088 0.0087
Schistosoma mansoni nAChR subunit 0.0023 0.0029 0.0029
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0123 0.0119
Mycobacterium ulcerans hydrolase 0.011 0.0338 0.1794
Loa Loa (eye worm) hypothetical protein 0.0071 0.0199 0.0198
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0157 0.0976
Trypanosoma brucei hypothetical protein, conserved 0.0206 0.0677 0.0674
Echinococcus granulosus mitogen activated protein kinase 0.0049 0.0123 0.0123
Schistosoma mansoni rab6-interacting 0.0019 0.0016 0.0016
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.0514 0.0513
Schistosoma mansoni autophagin-1 (C54 family) 0.0058 0.0152 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0016 0.0067
Schistosoma mansoni thyroid hormone receptor 0.0018 0.0011 0.0011
Plasmodium falciparum cysteine protease ATG4, putative 0.0022 0.0028 0.0039
Brugia malayi glutaminase DH11.1 0.0536 0.1839 0.1839
Brugia malayi Bromodomain containing protein 0.0031 0.0057 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0018 0.0011 0.0011
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0022 0.0028 0.006
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0016 0.0063
Schistosoma mansoni nAChR subunit 0.0023 0.0029 0.0029
Brugia malayi jmjC domain containing protein 0.0092 0.0274 0.0274
Entamoeba histolytica peptidase, C54 family 0.0022 0.0028 0.0066
Entamoeba histolytica hypothetical protein 0.0019 0.0016 0.0005
Plasmodium vivax histone deacetylase, putative 0.0225 0.0743 0.3829
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0016 0.0066
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0121 0.0121
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0618 0.2132 0.2131
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0075 0.0309
Loa Loa (eye worm) hypothetical protein 0.0023 0.0031 0.003
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0016 0.0016
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0102 0.031 0.0309
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0024 0.0033 0.0124
Schistosoma mansoni cpg binding protein 0.0028 0.0048 0.0048
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0146 0.0463 0.0462
Schistosoma mansoni polycystin 1-related 0.0096 0.0288 0.0288
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0144 0.0144
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0088 0.0088
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0031 0.008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0018 0.0011 0.0011
Schistosoma mansoni patched 1 0.0082 0.0239 0.0239
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0024 0.0033 0.0169
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0049 0.0123 0.0119
Loa Loa (eye worm) hypothetical protein 0.0307 0.1033 0.1032
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0199 0.0198
Schistosoma mansoni RAR-like nuclear receptor 0.0018 0.0011 0.0011
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0023 0.0031 0.0027
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0157 0.0157
Schistosoma mansoni DNA polymerase eta 0.0019 0.0016 0.0016
Brugia malayi Matrixin family protein 0.0091 0.0269 0.0268
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0023 0.0029 0.0028
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0049 0.0123 0.0264
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0016 0.0012
Echinococcus granulosus muscleblind protein 0.0146 0.0465 0.0464
Onchocerca volvulus 0.0023 0.0029 0.0071
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0075 0.0357
Onchocerca volvulus 0.0023 0.0029 0.0071
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0146 0.0463 0.0462
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0033 0.0066 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0016 0.0067
Echinococcus granulosus histone deacetylase 0.0526 0.1804 0.1804
Toxoplasma gondii hypothetical protein 0.1338 0.467 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0016
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0074 0.0304
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0016 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0107 0.0325 0.0325
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0018 0.0011 0.0011
Onchocerca volvulus 0.0039 0.0088 0.0314
Echinococcus multilocularis protein patched 0.0082 0.0239 0.0239
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0069 0.0068
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0024 0.0033 0.0134
Echinococcus multilocularis geminin 0.0868 0.3011 0.301
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Loa Loa (eye worm) ACC-1 protein 0.0023 0.0029 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0011 0.0011
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0079 0.0229 0.0229
Trichomonas vaginalis esterase, putative 0.0071 0.0199 0.0816
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.031 0.031
Echinococcus granulosus nibrin 0.0019 0.0016 0.0016
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0075 0.0075
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.0463 0.0463
Brugia malayi RNA binding protein 0.0125 0.0391 0.039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0088 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0044 0.0181
Onchocerca volvulus 0.0039 0.0088 0.0314
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0012
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0199 0.1031
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0199 0.0816
Loa Loa (eye worm) hypothetical protein 0.0091 0.0269 0.0268
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0031 0.0027
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0016 0.0012
Echinococcus granulosus p2X purinoceptor 4 0.0068 0.0188 0.0188
Leishmania major DNA polymerase kappa, putative 0.0019 0.0016 0.0012
Brugia malayi Inositol-1 0.0036 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0023 0.0031 0.003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0011 0.0043
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0114 0.0113
Schistosoma mansoni alpha-glucosidase 0.0138 0.0435 0.0435
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0114 0.0113
Echinococcus multilocularis carbonic anhydrase 0.1338 0.467 0.467
Brugia malayi Pre-SET motif family protein 0.0618 0.2132 0.2131
Brugia malayi beta-lactamase 0.0071 0.0199 0.0198
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0023 0.0029 0.0028
Echinococcus granulosus histone deacetylase 6 0.0526 0.1804 0.1804
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0452 0.1545 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0018 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0088 0.0088
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0016 0.0016
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0189 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0016 0.0067
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.019 0.019
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0038 0.006
Loa Loa (eye worm) histone deacetylase 3 0.0559 0.1924 0.1923
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0058 0.0152 0.0625
Brugia malayi Heterochromatin protein 1 0.0068 0.0189 0.0188
Trypanosoma cruzi histone deacetylase 1, putative 0.0559 0.1924 0.192
Brugia malayi Matrixin family protein 0.0091 0.0269 0.0268
Echinococcus granulosus cysteine protease atg4b 0.0058 0.0152 0.0151
Loa Loa (eye worm) hypothetical protein 0.0026 0.004 0.004
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0085 0.025 0.0249
Mycobacterium ulcerans lipase LipD 0.0071 0.0199 0.1031
Onchocerca volvulus 0.0128 0.0402 0.1613
Schistosoma mansoni transcription factor LCR-F1 0.0177 0.0573 0.0573
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0023 0.0029 0.0028
Onchocerca volvulus 0.0028 0.0048 0.0151
Loa Loa (eye worm) hypothetical protein 0.0028 0.0048 0.0048
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.1338 0.467 0.467
Brugia malayi T-complex protein 1, beta subunit 0.0023 0.0031 0.0031
Plasmodium falciparum histone deacetylase 1 0.0559 0.1924 0.4106
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1338 0.467 0.467
Echinococcus granulosus histone deacetylase 6 0.0526 0.1804 0.1804
Schistosoma mansoni hypothetical protein 0.0101 0.0306 0.0306
Plasmodium vivax SET domain protein, putative 0.0089 0.0264 0.1326
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0199 0.0816
Brugia malayi Melibiase family protein 0.0068 0.019 0.0189
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0082 0.0082
Toxoplasma gondii histone deacetylase HDAC1 0.0526 0.1804 0.3864
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0088 0.0088
Brugia malayi hypothetical protein 0.0177 0.0573 0.0573
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0123 0.0506
Loa Loa (eye worm) matrixin family protein 0.0201 0.0658 0.0657
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0019 0.0016 0.0035
Brugia malayi hypothetical protein 0.0025 0.0038 0.0037
Schistosoma mansoni histone deacetylase hda2 0.0225 0.0743 0.0743
Echinococcus multilocularis sterol regulatory element binding protein 0.0082 0.0239 0.0239
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0023 0.0029 0.0028
Entamoeba histolytica peptidase, C54 family 0.0022 0.0028 0.0066
Schistosoma mansoni alpha glucosidase 0.0036 0.0074 0.0074
Plasmodium falciparum histone deacetylase 2 0.0526 0.1804 0.385
Loa Loa (eye worm) hypothetical protein 0.0536 0.1842 0.1841
Loa Loa (eye worm) carbonic anhydrase 3 0.2848 1 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0022 0.0028 0.0024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0018 0.0011 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0123 0.0123
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0011 0.0043
Echinococcus granulosus geminin 0.0868 0.3011 0.301
Schistosoma mansoni histone deacetylase 4 5 0.0526 0.1804 0.1804
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0068 0.019 0.0779
Loa Loa (eye worm) hypothetical protein 0.0125 0.0389 0.0388
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0089 0.0264 0.0263
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.001 0.0022
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0023 0.0031 0.0128
Onchocerca volvulus Phospholipase A2 homolog 0.009 0.0266 0.1051
Echinococcus granulosus neuropeptide receptor A26 0.0456 0.156 0.1559
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0038 0.006
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0078 0.0078
Onchocerca volvulus 0.0039 0.0088 0.0314
Brugia malayi hypothetical protein 0.0019 0.0016 0.0016
Trypanosoma brucei histone deacetylase 1 0.0559 0.1924 0.192
Onchocerca volvulus 0.0023 0.0031 0.008
Echinococcus multilocularis histone deacetylase 1 0.0559 0.1924 0.1923
Entamoeba histolytica hypothetical protein 0.0177 0.0573 0.2923
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0016 0.0016
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0082 0.0081
Loa Loa (eye worm) ACC-1 protein 0.0023 0.0029 0.0028
Trypanosoma cruzi histone deacetylase, putative 0.0225 0.0743 0.0739
Onchocerca volvulus 0.0019 0.0016 0.002
Echinococcus granulosus chromobox protein 1 0.0068 0.0189 0.0188
Brugia malayi Cation transporter family protein 0.0023 0.0029 0.0028
Echinococcus granulosus p2X purinoceptor 4 0.0068 0.0188 0.0188
Schistosoma mansoni carbonic anhydrase 0.1338 0.467 0.467
Loa Loa (eye worm) hypothetical protein 0.0107 0.0325 0.0325
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0091 0.0269 0.0269
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0012
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0016 0.0015
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0023 0.0029 0.0028
Schistosoma mansoni DNA ligase IV 0.0019 0.0016 0.0016
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0029 0.0028
Echinococcus granulosus ecdysone induced protein 78C 0.0018 0.0011 0.0011
Echinococcus granulosus dna polymerase kappa 0.0019 0.0016 0.0015
Loa Loa (eye worm) voltage-gated potassium channel 0.0142 0.0449 0.0449
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0016 0.0057
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0031 0.0113
Echinococcus granulosus peregrin 0.0031 0.0057 0.0056
Schistosoma mansoni jumonji domain containing protein 0.0073 0.0208 0.0208
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0023 0.0031 0.0027
Echinococcus granulosus carbonic anhydrase II 0.2848 1 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Brugia malayi Hemopexin family protein 0.0128 0.0402 0.0401
Brugia malayi Putative carbonic anhydrase 5 precursor 0.2848 1 1
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0016 0.0012
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0102 0.0308 0.0308
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0088 0.0088
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0121 0.012
Schistosoma mansoni P2X receptor subunit 0.0068 0.0188 0.0188
Trypanosoma brucei protein kinase, putative 0.0049 0.0123 0.0119
Brugia malayi hypothetical protein 0.0039 0.0088 0.0087
Brugia malayi hypothetical protein 0.024 0.0798 0.0797
Leishmania major hypothetical protein, conserved 0.0025 0.0038 0.0034
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0023 0.0031 0.0031
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0023 0.0031 0.003
Schistosoma mansoni zinc finger protein 0.0022 0.0025 0.0025
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0023 0.0029 0.0028
Brugia malayi Doublecortin family protein 0.0019 0.0016 0.0016
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0018 0.0011 0.0011
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0011 0.0011
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0018 0.0011 0.0011
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0122 0.0121
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0074 0.007
Onchocerca volvulus 0.0071 0.0199 0.0773
Schistosoma mansoni lamin 0.0026 0.0042 0.0042
Echinococcus granulosus transmembrane protease serine 3 0.0039 0.0088 0.0087
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0196 0.0639 0.0639
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0088 0.0088
Echinococcus multilocularis histone deacetylase 8 0.0225 0.0743 0.0742
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0016
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0088 0.0088
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0012
Loa Loa (eye worm) hypothetical protein 0.0559 0.1924 0.1923
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0023 0.0031 0.0031
Schistosoma mansoni carbonic anhydrase-related 0.1338 0.467 0.467
Onchocerca volvulus 0.0093 0.0276 0.1091
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0199 0.0816
Loa Loa (eye worm) hypothetical protein 0.0071 0.0199 0.0198
Echinococcus granulosus glycine receptor subunit alpha 1 0.0023 0.0029 0.0028
Loa Loa (eye worm) histone deacetylase 1 0.0559 0.1924 0.1923
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0107 0.0325 0.0325
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0019 0.0016 0.0035
Echinococcus multilocularis histone deacetylase 0.0526 0.1804 0.1804
Echinococcus granulosus Protein patched homolog 1 0.0082 0.0239 0.0239
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0042 0.0041
Loa Loa (eye worm) hypothetical protein 0.0055 0.0144 0.0144
Brugia malayi T-complex protein 1, beta subunit 0.0023 0.0031 0.0031
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0148 0.0471 0.0471
Onchocerca volvulus 0.0071 0.0199 0.0773
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0018 0.0011 0.0011
Loa Loa (eye worm) TAR-binding protein 0.0125 0.0391 0.039
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0011 0.0011
Entamoeba histolytica hypothetical protein 0.0177 0.0573 0.2923
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0023 0.0029 0.0028
Onchocerca volvulus 0.0019 0.0016 0.0021
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0195 0.0636 0.0636
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0536 0.1842 0.1842
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0018 0.0011 0.0011
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0029 0.0028
Toxoplasma gondii Erv1 / Alr family protein 0.0033 0.0066 0.0142
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.0306 0.0305
Plasmodium vivax histone deacetylase, putative 0.0526 0.1804 0.9378
Echinococcus granulosus FTZ F1 alpha 0.0018 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0087
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0036 0.0035
Brugia malayi ecdysteroid receptor 0.0018 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0079 0.0229 0.0229
Loa Loa (eye worm) hepatopoietin HPO2 0.0033 0.0066 0.0066
Echinococcus granulosus tumor protein p63 0.0331 0.1116 0.1115
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0016
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0038 0.0147
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0088 0.0088
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0094 0.0384
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0087
Trichomonas vaginalis chaperonin, putative 0.0023 0.0031 0.0128
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0029 0.0028
Echinococcus granulosus Mastin 0.0039 0.0088 0.0087
Brugia malayi Augmenter of liver regeneration 0.0033 0.0066 0.0066
Echinococcus multilocularis tissue type plasminogen activator 0.0033 0.0066 0.0065
Toxoplasma gondii histone deacetylase HDAC4 0.0225 0.0743 0.159
Brugia malayi Trypsin family protein 0.0039 0.0088 0.0087
Onchocerca volvulus Matrilysin homolog 0.0091 0.0269 0.1062
Echinococcus granulosus tissue type plasminogen activator 0.0033 0.0066 0.0065
Loa Loa (eye worm) matrix metalloproteinase 0.0091 0.0269 0.0268
Brugia malayi hypothetical protein 0.0019 0.0016 0.0016
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0033 0.0029
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0144 0.0144
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.001 0.001
Schistosoma mansoni nAChR subunit 0.0023 0.0029 0.0029
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0023 0.0029 0.0028
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0029 0.0028
Schistosoma mansoni P2X receptor subunit 0.0068 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0011
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.1338 0.467 0.467
Loa Loa (eye worm) matrixin family protein 0.0219 0.0722 0.0721
Schistosoma mansoni P2X receptor subunit 0.0068 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0146 0.0465 0.0464
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0121 0.012
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0023 0.0029 0.0028
Brugia malayi TAR-binding protein 0.0125 0.0391 0.039
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0199 0.5662
Schistosoma mansoni hypothetical protein 0.0047 0.0114 0.0114
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0011 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0022 0.0028 0.0024
Brugia malayi hypothetical protein 0.0125 0.0389 0.0388
Onchocerca volvulus 0.0048 0.012 0.0447
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0016 0.003
Echinococcus multilocularis tumor protein p63 0.0331 0.1116 0.1115
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0058 0.0152 0.0151
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0074 0.0074
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0023 0.0029 0.0029
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0199 0.0198
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0016 0.0012
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0144 0.0144
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0048 0.0047
Echinococcus granulosus carbonic anhydrase 0.1338 0.467 0.467
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0192 0.0626 0.3199
Brugia malayi mbt repeat family protein 0.0049 0.0121 0.012
Echinococcus granulosus histone deacetylase 7 0.0526 0.1804 0.1804
Schistosoma mansoni eyes absent homolog 0.0085 0.0251 0.0251
Echinococcus multilocularis ecdysone induced protein 78C 0.0018 0.0011 0.0011
Echinococcus granulosus chromobox protein 1 0.0068 0.0189 0.0188
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0094 0.0384
Mycobacterium ulcerans hypothetical protein 0.0071 0.0199 0.1031
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0075 0.0161
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0016 0.0014
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0023 0.0029 0.0028
Echinococcus multilocularis FTZ F1 alpha 0.0018 0.0011 0.0011
Schistosoma mansoni lipoxygenase 0.008 0.0231 0.0231
Toxoplasma gondii ATPase, AAA family protein 0.0019 0.0016 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0018 0.0011 0.0011
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0033 0.0066 0.0062
Schistosoma mansoni hypothetical protein 0.0128 0.0402 0.0402
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0199 0.1031
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0023 0.0029 0.0028
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0199 0.1248
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0033 0.0066 0.0121
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0157 0.0156
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0154 0.0153
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0016 0.0004
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0087
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0123 0.0506
Loa Loa (eye worm) T-complex protein 1 0.0023 0.0031 0.0031
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.2848 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.0463 0.0463
Echinococcus multilocularis carbonic anhydrase 0.1338 0.467 0.467
Echinococcus granulosus histone deacetylase 1 0.0559 0.1924 0.1923
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0018 0.0011 0.0011
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0023 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0091 0.0269 0.0268
Leishmania major histone deacetylase, putative 0.0559 0.1924 0.192
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0391 0.0391
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0082 0.0239 0.0239
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0018 0.0011 0.0011
Trichomonas vaginalis histone deacetylase, putative 0.0559 0.1924 0.7906
Echinococcus multilocularis carbonic anhydrase II 0.2848 1 1
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0058 0.0152 0.0625
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0031 0.003
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0075 0.0075
Brugia malayi steroid hormone receptor 0.0018 0.0011 0.0011
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.001 0.001
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0023 0.0031 0.0083
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0123 0.0506
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0123 0.0506
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0157 0.0802
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0049 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0068 0.019 0.0189
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0011 0.0043
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0016
Trichomonas vaginalis replication factor C large subunit, putative 0.0019 0.0016 0.0067
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Brugia malayi Trypsin family protein 0.0039 0.0088 0.0087
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0089 0.0264 0.0565
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0018 0.0011 0.0011
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0033 0.0066 0.0062
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0033 0.0029
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.2848 1 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0016
Echinococcus multilocularis enteropeptidase 0.0039 0.0088 0.0087
Leishmania major hypothetical protein, conserved 0.0071 0.0199 0.0195
Echinococcus multilocularis glycoprotein Antigen 5 0.0039 0.0088 0.0087
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0391 0.0391
Entamoeba histolytica peptidase, C54 family 0.0022 0.0028 0.0066
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0087
Echinococcus granulosus glycine receptor subunit alpha 1 0.0023 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Schistosoma mansoni hypothetical protein 0.0079 0.0229 0.0229
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0114 0.0113
Brugia malayi Histone deacetylase family protein 0.0526 0.1804 0.1804
Echinococcus granulosus citrate lyase subunit beta protein 0.0024 0.0033 0.0032
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0066 0.0062
Brugia malayi DKFZp564C0469 protein 0.0019 0.0016 0.0016
Schistosoma mansoni zinc finger protein 0.0016 0.0004 0.0004
Schistosoma mansoni P2X receptor subunit 0.0068 0.0188 0.0188
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0023 0.0029 0.0029
Brugia malayi histone deacetylase 1 (HD1) 0.0559 0.1924 0.1923
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0514 0.0513
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0033 0.0124
Trypanosoma cruzi hypothetical protein, conserved 0.0206 0.0677 0.0674
Echinococcus granulosus histone deacetylase 3 0.0559 0.1924 0.1923
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0031 0.0113
Loa Loa (eye worm) hypothetical protein 0.0047 0.0114 0.0113
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0074 0.007
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0016 0.0057
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0009
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0075 0.0309
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0023 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0049 0.0121 0.012
Leishmania major DNA polymerase eta, putative 0.0019 0.0016 0.0012
Loa Loa (eye worm) RNA binding protein 0.0125 0.0391 0.039
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0011
Echinococcus multilocularis Niemann Pick C1 protein 0.0192 0.0626 0.0625
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0012
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0088 0.0088
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0018 0.0011 0.0011
Echinococcus multilocularis mitogen activated protein kinase 0.0049 0.0123 0.0123
Onchocerca volvulus 0.0071 0.0199 0.0773
Brugia malayi Niemann-Pick C1 protein precursor 0.0192 0.0626 0.0625
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0031 0.0113
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0018 0.0011 0.0011
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0199 0.0985
Echinococcus multilocularis muscleblind protein 0.0146 0.0465 0.0464
Echinococcus multilocularis tar DNA binding protein 0.0125 0.0391 0.039
Mycobacterium leprae PROBABLE HYDROLASE 0.011 0.0338 1
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0031 0.003
Trypanosoma brucei histone deacetylase 4 0.0526 0.1804 0.1801
Echinococcus granulosus survival motor neuron protein 1 0.024 0.0798 0.0797
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0121 0.012
Trichomonas vaginalis histone deacetylase, putative 0.0559 0.1924 0.7906
Loa Loa (eye worm) hypothetical protein 0.0065 0.0178 0.0177
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0011 0.0011
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0016 0.0067
Giardia lamblia TCP-1 chaperonin subunit beta 0.0023 0.0031 0.0083
Trypanosoma cruzi histone deacetylase, putative 0.0526 0.1804 0.1801
Echinococcus granulosus expressed conserved protein 0.018 0.0585 0.0584
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0049 0.0123 0.0119
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0147 0.0469 0.0468
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0094 0.034
Echinococcus multilocularis transmembrane protease serine 3 0.0039 0.0088 0.0087
Schistosoma mansoni survival motor neuron protein 0.0049 0.0122 0.0122
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0031 0.0113
Brugia malayi Trypsin family protein 0.0039 0.0088 0.0087
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.019 0.019
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0016 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0044 0.0181
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0199 0.0195
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0029 0.0028
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0156 0.0335
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0016 0.0012
Echinococcus multilocularis neuropeptide s receptor 0.0456 0.156 0.1559
Leishmania major histone deacetylase, putative 0.0559 0.1924 0.192
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0074 0.0304
Schistosoma mansoni alpha-glucosidase 0.0138 0.0435 0.0435
Brugia malayi Matrixin family protein 0.0219 0.0722 0.0721
Onchocerca volvulus Huntingtin homolog 0.0125 0.0389 0.1557
Toxoplasma gondii melibiase subfamily protein 0.0102 0.031 0.0664
Echinococcus granulosus GPCR family 2 0.0047 0.0114 0.0113
Echinococcus granulosus nuclear receptor co repressor related ncor 0.0277 0.0927 0.0927
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0102 0.031 0.0309
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0327 0.1102 0.7122
Schistosoma mansoni nAChR subunit 0.0023 0.0029 0.0029
Schistosoma mansoni histone deacetylase 4 5 0.0526 0.1804 0.1804
Loa Loa (eye worm) steroid hormone receptor 0.0018 0.0011 0.0011
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0199 0.1248
Echinococcus granulosus cpg binding protein 0.0032 0.006 0.006
Schistosoma mansoni hypothetical protein 0.0047 0.0114 0.0114
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0039 0.0088 0.0087
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0016 0.0015
Schistosoma mansoni hypothetical protein 0.03 0.1007 0.1007
Brugia malayi topoisomerase 0.0019 0.0016 0.0016
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0049 0.0123 0.0119
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0023 0.0029 0.0028
Brugia malayi intermediate filament protein 0.0026 0.0042 0.0041
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0029 0.0028
Brugia malayi follicle stimulating hormone receptor 0.0696 0.2405 0.2405
Loa Loa (eye worm) glutaminase 0.0536 0.1839 0.1839
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0199 0.0816
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0011 0.0011
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0083 0.0298
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0199 0.0816
Echinococcus multilocularis expressed conserved protein 0.018 0.0585 0.0584
Loa Loa (eye worm) hypothetical protein 0.0101 0.0305 0.0304
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0033 0.0029
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0058 0.0152 0.0625
Plasmodium falciparum phd finger protein, putative 0.0028 0.0048 0.0082
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0082 0.0239 0.0239
Brugia malayi beta-lactamase family protein 0.0071 0.0199 0.0198
Entamoeba histolytica peptidase, C54 family 0.0058 0.0152 0.0716
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0009
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0016 0.0012
Loa Loa (eye worm) TK/ROR protein kinase 0.0033 0.0066 0.0065
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0058 0.0152 0.0625
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0199 0.1248
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0023 0.0029 0.0028
Echinococcus granulosus lamin 0.0026 0.0042 0.0041
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0062 0.1418
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0031 0.008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.1338 0.467 0.467
Brugia malayi photoreceptor-specific nuclear receptor 0.0018 0.0011 0.0011
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0074 0.0304
Onchocerca volvulus Matrix metalloproteinase homolog 0.0201 0.0658 0.2669
Onchocerca volvulus 0.0039 0.0088 0.0314
Brugia malayi Pre-SET motif family protein 0.0089 0.0264 0.0263
Echinococcus multilocularis replication factor c subunit 1 0.0019 0.0016 0.0016
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0058 0.0152 0.0148
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0023 0.0029 0.0028
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0038 0.0082
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0048 0.0048
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0058 0.0152 0.0625
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0147 0.0469 0.0468
Trypanosoma cruzi histone deacetylase, putative 0.0526 0.1804 0.1801
Brugia malayi Histone deacetylase family protein 0.0526 0.1804 0.1804
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0075 0.0071
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0016 0.0015
Echinococcus multilocularis histone deacetylase 6 0.0526 0.1804 0.1804
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0391 0.0391
Loa Loa (eye worm) LGC-31 protein 0.0023 0.0029 0.0028
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0016 0.003
Onchocerca volvulus 0.0049 0.0122 0.0457
Schistosoma mansoni nAChR subunit 0.0023 0.0029 0.0029
Echinococcus multilocularis neuropeptide receptor A26 0.0456 0.156 0.1559
Wolbachia endosymbiont of Brugia malayi extracellular metallopeptidase 0.0874 0.3034 1
Echinococcus multilocularis histone deacetylase 3 0.0559 0.1924 0.1923
Mycobacterium tuberculosis Conserved protein 0.0071 0.0199 0.1248
Giardia lamblia Kinase, CMGC MAPK 0.0049 0.0123 0.0565
Loa Loa (eye worm) hypothetical protein 0.011 0.0338 0.0338
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0016 0.0066
Loa Loa (eye worm) glutaminase 2 0.0536 0.1839 0.1839
Brugia malayi hypothetical protein 0.0085 0.0251 0.025
Echinococcus multilocularis p2X purinoceptor 4 0.0068 0.0188 0.0188
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0016 0.0016
Schistosoma mansoni ap endonuclease 0.0019 0.0016 0.0016
Schistosoma mansoni chromobox protein 0.0068 0.0189 0.0189
Onchocerca volvulus 0.0026 0.0042 0.0126
Echinococcus multilocularis glycine receptor subunit beta 0.0023 0.0029 0.0028
Giardia lamblia Replication factor C, subunit 1 0.0019 0.0016 0.0005
Mycobacterium ulcerans hypothetical protein 0.0023 0.0031 0.0113
Onchocerca volvulus 0.0023 0.0029 0.0071
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0074 0.0304
Echinococcus multilocularis cysteine protease atg4b 0.0058 0.0152 0.0151
Onchocerca volvulus 0.0049 0.0121 0.0451
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0199 0.0195
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0147 0.0469 0.0468
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0023 0.0031 0.0031
Echinococcus multilocularis Peptidase C54 0.0058 0.0152 0.0151
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0114 0.0353 0.0352
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0102 0.031 0.0309
Loa Loa (eye worm) hypothetical protein 0.0225 0.0743 0.0742
Echinococcus granulosus glycine receptor subunit beta 0.0023 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0042 0.0096 0.0095
Echinococcus granulosus histone lysine methyltransferase setb 0.0107 0.0325 0.0325
Schistosoma mansoni thyroid hormone receptor 0.0018 0.0011 0.0011
Treponema pallidum DNA ligase (lig) 0.0019 0.0016 1
Mycobacterium ulcerans hypothetical protein 0.0024 0.0033 0.0124
Echinococcus granulosus Niemann Pick C1 protein 0.0274 0.0917 0.0916
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0011
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0075 0.0071
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0123 0.0119
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0559 0.1924 0.7906
Brugia malayi mbt repeat family protein 0.0049 0.0121 0.012
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0016 0.0012
Echinococcus granulosus carbonic anhydrase 0.1338 0.467 0.467
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0023 0.0031 0.0031
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0033 0.0124
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0023 0.0029 0.0028
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.011 0.0338 0.0338
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0121 0.0121
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0048 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0016 0.0067
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0169 0.0169
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0031 0.008
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.01 0.0303 0.0303
Toxoplasma gondii histone deacetylase HDAC2 0.0559 0.1924 0.4119
Brugia malayi Bromodomain containing protein 0.0078 0.0225 0.0224
Echinococcus granulosus enteropeptidase 0.0039 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.024 0.0798 0.0797
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0016 0.0016
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0031 0.0113
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0049 0.0123 0.0119
Trypanosoma cruzi histone deacetylase, putative 0.0225 0.0743 0.0739
Trypanosoma brucei unspecified product 0.0019 0.0016 0.0012
Trichomonas vaginalis histone deacetylase, putative 0.0559 0.1924 0.7906
Mycobacterium tuberculosis Conserved protein 0.0071 0.0199 0.1248
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0016 0.0015
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0019 0.0016 0.0016
Schistosoma mansoni cpg binding protein 0.0032 0.006 0.006
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0074 0.0074
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0016 0.0015
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0199 0.0198
Brugia malayi RNA recognition motif domain containing protein 0.0125 0.0391 0.039
Echinococcus granulosus p2X purinoceptor 4 0.0068 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0071 0.0199 0.0198
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0074 0.0304
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.2848 1 1
Echinococcus multilocularis zinc finger protein 0.0022 0.0025 0.0024
Loa Loa (eye worm) trypsin family protein 0.0039 0.0088 0.0087
Schistosoma mansoni histone deacetylase 1 2 3 0.0225 0.0743 0.0743
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0062 0.036
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0009
Echinococcus granulosus dna polymerase eta 0.0019 0.0016 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0083 0.0342
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0016 0.0067
Echinococcus granulosus mitogen activated protein kinase 3 0.0049 0.0123 0.0123
Echinococcus multilocularis Niemann Pick C1 protein 0.0274 0.0917 0.0916
Echinococcus multilocularis glycine receptor subunit beta 0.0023 0.0029 0.0028
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0075 0.0071
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0088 0.0088
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0016 0.0016
Schistosoma mansoni intermediate filament proteins 0.0026 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0071 0.0199 0.0198
Echinococcus multilocularis peregrin 0.0031 0.0057 0.0056
Echinococcus multilocularis p2X purinoceptor 4 0.0068 0.0188 0.0188
Schistosoma mansoni hypothetical protein 0.0177 0.0573 0.0573
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.0029 0.0028
Loa Loa (eye worm) histone deacetylase 11 0.0225 0.0743 0.0742
Entamoeba histolytica peptidase, C54 family 0.0022 0.0028 0.0066
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0039 0.0088 0.0087
Schistosoma mansoni cercarial elastase (S01 family) 0.0039 0.0088 0.0088
Brugia malayi Phospholipase A2 family protein 0.009 0.0266 0.0265
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0022 0.0028 0.0024
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0016 0.0016
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0023 0.0029 0.0028
Brugia malayi Cation transporter family protein 0.0023 0.0029 0.0028
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0011 0.0011
Brugia malayi jmjC domain containing protein 0.0038 0.0082 0.0081
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0016 0.0033
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0087 0.0087
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0088 0.0087
Brugia malayi PHD-finger family protein 0.0027 0.0044 0.0044
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0023 0.0029 0.0029
Brugia malayi Matrixin family protein 0.0091 0.0269 0.0268
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0011 0.0043
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0189 0.0776
Echinococcus multilocularis p2X purinoceptor 4 0.0068 0.0188 0.0188
Schistosoma mansoni hypothetical protein 0.0033 0.0066 0.0066
Echinococcus granulosus Peptidase C54 0.0058 0.0152 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0083 0.0342
Brugia malayi hypothetical protein 0.0019 0.0016 0.0016
Onchocerca volvulus 0.0536 0.1842 0.7558
Echinococcus granulosus histone deacetylase 6 0.0532 0.1826 0.1826
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0016 0.0012
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0074 0.0304
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0016 0.0033
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0074 0.0304
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0559 0.1924 0.7906
Loa Loa (eye worm) hypothetical protein 0.0065 0.0178 0.0177
Loa Loa (eye worm) hypothetical protein 0.0033 0.0066 0.0065
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0012
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0033 0.0066 0.0291
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0114 0.0113
Brugia malayi CXXC zinc finger family protein 0.0028 0.0048 0.0047
Leishmania major carbonic anhydrase-like protein 0.2848 1 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.031 0.031
Brugia malayi hypothetical protein 0.0019 0.0016 0.0016
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0039 0.0088 0.0087
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0391 0.0391
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.1338 0.467 0.467
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0018 0.0011 0.0011
Echinococcus granulosus nAChR subunit 0.0023 0.0029 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0016
Brugia malayi Peptidase family C54 containing protein 0.0058 0.0152 0.0151
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0015
Schistosoma mansoni nAChR subunit 0.0023 0.0029 0.0029
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0121 0.0121
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0039 0.0088 0.0088
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Schistosoma mansoni loxhd1 0.0019 0.0016 0.0016
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0114 0.0113
Leishmania major hypothetical protein, conserved 0.0033 0.0066 0.0062
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0199 0.0195
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0016
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0016 0.0067
Echinococcus granulosus neuropeptide s receptor 0.0456 0.156 0.1559
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0016 0.0012
Brugia malayi hypothetical protein 0.0016 0.0006 0.0006
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0016 0.0063
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0023 0.0029 0.0028
Trypanosoma brucei histone deacetylase, putative 0.0526 0.1804 0.1801
Plasmodium vivax replication factor C subunit 1, putative 0.0019 0.0016 0.0033
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0199 0.1248
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0016 0.0012
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0023 0.0022
Schistosoma mansoni lipoxygenase 0.0114 0.0353 0.0353
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0023 0.0029 0.0028
Giardia lamblia Histone deacetylase 0.0559 0.1924 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0146 0.0463 0.0462
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0107 0.0325 0.0325
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0023 0.0029 0.0028
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0559 0.1924 0.7906
Onchocerca volvulus 0.0704 0.2433 1
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0196 0.0639 0.0639
Brugia malayi Trypsin family protein 0.0536 0.1842 0.1841
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0048 0.0103
Chlamydia trachomatis DNA ligase 0.0019 0.0016 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1338 0.467 0.467
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0012
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0011 0.0011
Toxoplasma gondii ABC1 family protein 0.0071 0.0199 0.0425
Loa Loa (eye worm) hypothetical protein 0.0301 0.1011 0.101
Trichomonas vaginalis set domain proteins, putative 0.0704 0.2433 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0146 0.0463 0.0462
Entamoeba histolytica hypothetical protein 0.0177 0.0573 0.2923
Echinococcus multilocularis GPCR, family 2 0.0047 0.0114 0.0113
Brugia malayi nuclear hormone receptor 0.0018 0.0011 0.0011
Toxoplasma gondii kringle domain-containing protein 0.0033 0.0066 0.0141
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0199 0.1248
Loa Loa (eye worm) hypothetical protein 0.0048 0.012 0.0119
Echinococcus granulosus glycine receptor subunit beta 0.0023 0.0029 0.0028
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0157 0.0156
Onchocerca volvulus Alhambra homolog 0.0028 0.0048 0.0152
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0065 0.0178 0.0177
Toxoplasma gondii t-complex protein beta subunit 0.0023 0.0031 0.0067
Trypanosoma brucei carbonic anhydrase-like protein 0.2848 1 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0018 0.0011 0.0011
Schistosoma mansoni rab6-interacting 0.0019 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0079 0.0229 0.0229
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0391 0.0391
Echinococcus multilocularis dna polymerase eta 0.0019 0.0016 0.0015
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0018 0.0011 0.0011
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0074 0.0308
Schistosoma mansoni coup transcription factor 0.0018 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0047 0.0114 0.0114
Plasmodium falciparum histone deacetylase, putative 0.0526 0.1804 0.385
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0114 0.0113
Brugia malayi Calcitonin receptor-like protein seb-1 0.0148 0.0471 0.0471
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0092 0.0274 0.0274
Onchocerca volvulus Huntingtin homolog 0.0125 0.0389 0.1557
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0078 0.0078
Brugia malayi nuclear receptor NHR-88 0.0018 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0049 0.0122 0.0122
Echinococcus multilocularis lamin dm0 0.0026 0.0042 0.0041
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0329 0.1111 0.111
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0018 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0039 0.0088 0.0088
Schistosoma mansoni cpg binding protein 0.0032 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.1338 0.467 0.467
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0101 0.0306 0.0305
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0039 0.0088 0.0087
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0023 0.0029 0.0028
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0016 0.0035
Schistosoma mansoni glutaminase 0.0536 0.1839 0.1839
Loa Loa (eye worm) MBCTL1 0.0055 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0025 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0016
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0023 0.0029 0.0028
Echinococcus granulosus tar DNA binding protein 0.0125 0.0391 0.039
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0169 0.0169
Schistosoma mansoni hypothetical protein 0.0028 0.0048 0.0048
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0023 0.0029 0.0028
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0075 0.0313
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0018 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0028
Brugia malayi PHD-finger family protein 0.0028 0.0048 0.0048
Trypanosoma cruzi FHA domain containing protein, putative 0.0019 0.0016 0.0012
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0001 0.0001
Plasmodium falciparum carbonic anhydrase 0.1338 0.467 1
Onchocerca volvulus 0.0019 0.0016 0.002
Echinococcus multilocularis Mastin 0.0039 0.0088 0.0087
Entamoeba histolytica histone deacetylase, putative 0.0559 0.1924 1
Onchocerca volvulus Putative nachr subunit 0.0023 0.0029 0.0071
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0009
Echinococcus multilocularis survival motor neuron protein 1 0.024 0.0798 0.0797
Toxoplasma gondii histone deacetylase HDAC3 0.0559 0.1924 0.4119
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0016 0.0012
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0011
Onchocerca volvulus Matrilysin homolog 0.0201 0.0658 0.2669
Echinococcus granulosus glycoprotein Antigen 5 0.0039 0.0088 0.0087
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0031 0.0113
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0157 0.0802
Schistosoma mansoni ap endonuclease 0.0019 0.0016 0.0016
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0189 0.0776
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0023 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0072 0.0204 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0239 0.0983
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0536 0.1842 0.1842
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2399 0.8415 0.8415
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0023 0.0029 0.0028
Echinococcus granulosus glycine receptor subunit alpha 1 0.0023 0.0029 0.0028
Brugia malayi histone deacetylase 11 0.0225 0.0743 0.0742
Loa Loa (eye worm) hypothetical protein 0.0536 0.1842 0.1841
Loa Loa (eye worm) hypothetical protein 0.0192 0.0626 0.0625
Trichomonas vaginalis glutaminase, putative 0.0536 0.1839 0.7559
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0696 0.2405 0.2405
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.0029 0.0028
Onchocerca volvulus 0.0497 0.1703 0.6986
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0199 0.1248
Echinococcus multilocularis RUN 0.0019 0.0016 0.0016
Onchocerca volvulus 0.003 0.0054 0.0178
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0125 0.0391 0.039
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0018 0.0011 0.0011
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0016 0.0016
Onchocerca volvulus Histone deacetylase 10 homolog 0.0225 0.0743 0.302
Brugia malayi chromobox protein homolog 3 0.0038 0.0083 0.0083
Entamoeba histolytica hypothetical protein 0.0177 0.0573 0.2923
Brugia malayi CHE-14 protein 0.0082 0.0239 0.0239
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0018 0.0011 0.0011
Schistosoma mansoni topbp1 0.0019 0.0016 0.0016
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0031 0.0445
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0074 0.0308
Mycobacterium tuberculosis Conserved protein 0.0071 0.0199 0.1248
Loa Loa (eye worm) histone deacetylase 0.0526 0.1804 0.1804
Mycobacterium ulcerans hypothetical protein 0.0024 0.0033 0.0124
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0023 0.0029 0.0029
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0023 0.0029 0.0028
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1338 0.467 0.467
Loa Loa (eye worm) hypothetical protein 0.0146 0.0465 0.0464
Schistosoma mansoni nAChR subunit 0.0023 0.0029 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0016 0.0012
Giardia lamblia PHD finger protein 15 0.0028 0.0048 0.0172
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0157 0.0336
Onchocerca volvulus 0.0023 0.0029 0.0071
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0022 0.0028 0.0024
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0031 0.0156
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0023 0.0029 0.0028
Trichomonas vaginalis histone deacetylase, putative 0.0559 0.1924 0.7906
Echinococcus granulosus carbonic anhydrase 0.1338 0.467 0.467
Echinococcus multilocularis mitogen activated protein kinase 3 0.0049 0.0123 0.0123
Trypanosoma brucei glucosidase, putative 0.0036 0.0074 0.007
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0033 0.0066 0.0066
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0023 0.0029 0.0028
Trypanosoma cruzi histone deacetylase 1, putative 0.0559 0.1924 0.192
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0074 0.007
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0016 0.0016
Schistosoma mansoni steroid hormone receptor ad4bp 0.0018 0.0011 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0012
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0058 0.0152 0.0152
Mycobacterium ulcerans glutaminase 0.0536 0.1839 1
Trypanosoma brucei histone deacetylase 2 0.0225 0.0743 0.0739
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0031 0.0027
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0147 0.0469 0.0469
Brugia malayi MAP kinase sur-1 0.0049 0.0123 0.0123
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.2848 1 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0031 0.0113
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.2848 1 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0075 0.0071
Plasmodium falciparum T-complex protein 1 subunit beta 0.0023 0.0031 0.0046
Plasmodium falciparum cysteine repeat modular protein 1 0.0033 0.0066 0.012
Schistosoma mansoni histone deacetylase 0.0559 0.1924 0.1924
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0199 0.1248
Echinococcus multilocularis histone deacetylase 6 0.0526 0.1804 0.1804
Onchocerca volvulus 0.0023 0.0029 0.0071
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0058 0.0152 0.0152
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0042 0.0041
Echinococcus multilocularis carbonic anhydrase 0.1338 0.467 0.467
Loa Loa (eye worm) hypothetical protein 0.0045 0.0108 0.0107
Brugia malayi Cation transporter family protein 0.0023 0.0029 0.0028
Schistosoma mansoni inositol monophosphatase 0.0036 0.0075 0.0075
Echinococcus granulosus intermediate filament protein 0.0026 0.0042 0.0041
Trichomonas vaginalis histone deacetylase, putative 0.0559 0.1924 0.7906
Loa Loa (eye worm) hypothetical protein 0.0091 0.0269 0.0268
Schistosoma mansoni carbonic anhydrase-related 0.1338 0.467 0.467
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0019 0.0016 0.0005
Trypanosoma brucei histone deacetylase 3 0.0526 0.1804 0.1801
Schistosoma mansoni histone deacetylase 0.0559 0.1924 0.1924
Schistosoma mansoni hypothetical protein 0.0019 0.0016 0.0016
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0144 0.0144
Schistosoma mansoni hypothetical protein 0.0039 0.0088 0.0088
Loa Loa (eye worm) beta-lactamase 0.0071 0.0199 0.0198
Mycobacterium ulcerans beta-lactamase 0.0071 0.0199 0.1031

Activities

Activity type Activity value Assay description Source Reference
Change (functional) = -2 % Percent change in Geller-Seifter conflict schedule was determined in Long-Evans rats after (po)administration of gavage of 25 mg/kg ChEMBL. 1967311
IC50 (binding) = 0.034 uM Inhibition of specific binding of 1.5 nM [3H]-diazepam to rat brain benzodiazepine receptors ChEMBL. 1967311
IC50 (binding) = 0.034 uM Inhibition of specific binding of 1.5 nM [3H]-diazepam to rat brain benzodiazepine receptors ChEMBL. 1967311

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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