Detailed information for compound 927785

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 466.607 | Formula: C23H39NaO6S
  • H donors: 3 H acceptors: 5 LogP: 4.35 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCC[C@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2[C@@H](O)C[C@H]2[C@]1(C)CC[C@H](C2)OS(=O)(=O)[O-])C.[Na+]
  • InChi: 1S/C23H40O6S.Na/c1-14(8-11-24)17-4-5-18-21-19(7-10-23(17,18)3)22(2)9-6-16(29-30(26,27)28)12-15(22)13-20(21)25;/h14-21,24-25H,4-13H2,1-3H3,(H,26,27,28);/q;+1/p-1/t14-,15+,16-,17-,18+,19+,20+,21+,22+,23-;/m1./s1
  • InChiKey: ZCJMXSITOYNADP-RDYGPAGHSA-M  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0051 0.0015 0.0074
Loa Loa (eye worm) hypothetical protein 0.0051 0.0015 0.0074
Loa Loa (eye worm) hypothetical protein 0.0051 0.0015 0.0074
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0199 0.0107 0.7823
Echinococcus multilocularis neuropeptides capa receptor 0.0264 0.0147 0.0146
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0243 0.0134 0.2716
Entamoeba histolytica elongation factor-2 kinase, putative 0.0301 0.017 0.7345
Brugia malayi Smad1 0.022 0.012 0.0593
Brugia malayi Latrophilin receptor protein 2 0.0111 0.0052 0.0255
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0264 0.0147 0.073
Mycobacterium tuberculosis Probable oxidoreductase 0.0243 0.0134 0.2749
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0058 0.0019 0.0093
Plasmodium vivax ataxin-2 like protein, putative 0.0301 0.017 0.3641
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0264 0.0147 0.0779
Brugia malayi latrophilin 2 splice variant baaae 0.0239 0.0131 0.0651
Brugia malayi Serotonin receptor 0.0264 0.0147 0.0729
Brugia malayi Nuclear hormone receptor-like 1 0.0072 0.0028 0.0135
Schistosoma mansoni ap endonuclease 0.004 0.0008 0.0017
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4895 0.3006 0.3005
Echinococcus multilocularis neuropeptide s receptor 0.0264 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Brugia malayi von Willebrand factor type A domain containing protein 0.0301 0.017 0.0844
Giardia lamblia GTOR 0.0247 0.0136 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0028 0.0027
Brugia malayi jmjC domain containing protein 0.0097 0.0044 0.0213
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0031 0.0003 0.0002
Echinococcus multilocularis chromobox protein 1 0.0076 0.003 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0033 0.0345
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0225 0.0123 0.0609
Leishmania major DNA polymerase eta, putative 0.0105 0.0049 0.0487
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0009 0.0008
Trichomonas vaginalis bromodomain-containing protein, putative 0.009 0.0039 0.0208
Trichomonas vaginalis helicase, putative 0.0027 0 0.0000028905
Brugia malayi Carboxylesterase family protein 0.0051 0.0015 0.0072
Brugia malayi neuropeptide F receptor 0.0264 0.0147 0.0729
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0005 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0017 0.0091
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0054 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0301 0.017 0.0845
Leishmania major trypanothione reductase 0.0096 0.0043 0.0423
Loa Loa (eye worm) hypothetical protein 0.0051 0.0015 0.0074
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0339 0.0193 0.0962
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0134 0.0067 0.0151
Schistosoma mansoni opsin-like receptor 0.0264 0.0147 0.0335
Loa Loa (eye worm) hypothetical protein 0.0098 0.0044 0.0219
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0051 0.0015 0.0014
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0404 0.0233 0.0232
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0301 0.017 0.0905
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0058 0.0019 0.0102
Plasmodium falciparum ataxin-2 like protein, putative 0.0301 0.017 0.3625
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0264 0.0147 0.0335
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0134 0.0067 0.0066
Entamoeba histolytica hypothetical protein 0.0054 0.0017 0.0411
Trypanosoma brucei polo-like protein kinase 0.0099 0.0045 0.0476
Schistosoma mansoni smad 0.022 0.012 0.0273
Schistosoma mansoni hypothetical protein 0.1678 0.102 0.234
Trichomonas vaginalis DNA polymerase eta, putative 0.0079 0.0033 0.0173
Loa Loa (eye worm) nuclear hormone receptor 0.0034 0.0005 0.002
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0512 0.03 0.6358
Schistosoma mansoni steroid hormone receptor ad4bp 0.0072 0.0028 0.0062
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0512 0.03 0.6277
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0089 0.0039 0.0038
Echinococcus granulosus hypothetical protein 0.0264 0.0147 0.0146
Echinococcus granulosus somatostatin receptor 0.0264 0.0147 0.0146
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0264 0.0147 0.0335
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0264 0.0147 0.0146
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0111 0.0052 0.0051
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0264 0.0147 0.0335
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0072 0.0028 0.0137
Loa Loa (eye worm) hypothetical protein 0.0304 0.0171 0.0852
Brugia malayi hypothetical protein 0.0264 0.0147 0.0729
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0008 0.0041
Onchocerca volvulus 0.0301 0.017 0.0901
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Plasmodium vivax thioredoxin reductase, putative 0.0096 0.0043 0.092
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0048 0.0013 0.0133
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0007 0.0031
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0089 0.0039 0.0378
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0033 0.0004 0.0033
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0264 0.0147 0.0146
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0012 0.0058
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0045 0.01
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1511 0.0916 1
Brugia malayi Serotonin receptor 0.0264 0.0147 0.0729
Echinococcus multilocularis para nitrobenzyl esterase 0.0051 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Loa Loa (eye worm) thioredoxin reductase 0.0096 0.0043 0.0211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0089 0.0039 0.0206
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0038 0.0007 0.0014
Echinococcus multilocularis neuropeptide receptor 0.0264 0.0147 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0000028905
Echinococcus multilocularis nuclear receptor nhr 48 0.0034 0.0005 0.0004
Mycobacterium tuberculosis Probable aminotransferase 0.0296 0.0167 0.3453
Schistosoma mansoni hypothetical protein 0.0301 0.017 0.0388
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0139 0.0739
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0042 0.001 0.0118
Echinococcus granulosus rhodopsin orphan GPCR 0.0264 0.0147 0.0146
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0079 0.0033 0.0605
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0003 0.0005
Brugia malayi nuclear hormone receptor 0.0034 0.0005 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0076 0.0406
Brugia malayi ORL1-like opioid receptor 0.0264 0.0147 0.0729
Trypanosoma brucei unspecified product 0.0079 0.0033 0.0345
Schistosoma mansoni TGF-beta signal transducer Smad2 0.022 0.012 0.0273
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0247 0.0136 0.1465
Toxoplasma gondii hypothetical protein 0.0244 0.0134 0.2862
Loa Loa (eye worm) hypothetical protein 0.0105 0.0049 0.024
Brugia malayi nuclear receptor RXR 0.0038 0.0007 0.0031
Echinococcus multilocularis mothers against decapentaplegic 6 0.0098 0.0044 0.0043
Schistosoma mansoni ferritin light chain 0.0085 0.0036 0.0081
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0247 0.0136 0.0135
Echinococcus multilocularis sodium channel protein 0.0136 0.0068 0.0067
Toxoplasma gondii von Willebrand factor type A domain-containing protein 0.0301 0.017 0.3629
Brugia malayi RNA binding protein 0.0131 0.0064 0.0317
Brugia malayi MH2 domain containing protein 0.022 0.012 0.0593
Loa Loa (eye worm) hypothetical protein 0.0072 0.0028 0.0137
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.002
Schistosoma mansoni biogenic amine receptor 0.0264 0.0147 0.0335
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0134 0.0067 0.0066
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0264 0.0147 0.0335
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0315 0.0178 0.7719
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0264 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0301 0.017 0.0845
Echinococcus multilocularis dnaJ subfamily B 0.1678 0.102 0.1019
Echinococcus granulosus G protein coupled receptor 139 0.0264 0.0147 0.0146
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0247 0.0136 0.1444
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0014 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0264 0.0147 0.0335
Schistosoma mansoni amine GPCR 0.0264 0.0147 0.0335
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0048 0.0013 0.0124
Brugia malayi nuclear hormone receptor family member nhr-6 0.0034 0.0005 0.0018
Loa Loa (eye worm) hypothetical protein 0.0037 0.0007 0.003
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0085 0.0036 0.0681
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0072 0.0028 0.0135
Toxoplasma gondii target of rapamycin (TOR), putative 0.0186 0.0098 0.2094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0138 0.0069 0.0365
Onchocerca volvulus 0.0051 0.0015 0.0077
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0072 0.0028 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0000028905
Onchocerca volvulus Neuropeptide F receptor homolog 0.0264 0.0147 0.0779
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0018 0.0179
Trichomonas vaginalis chromobox protein, putative 0.0076 0.003 0.0161
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.001 0.0052
Brugia malayi G-protein coupled receptor 0.0264 0.0147 0.0729
Brugia malayi Carboxylesterase family protein 0.0051 0.0015 0.0072
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0054 0.0017 0.0177
Loa Loa (eye worm) hypothetical protein 0.0035 0.0005 0.0022
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0006 0.0005
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0038 0.0007 0.0006
Plasmodium falciparum circumsporozoite- and TRAP-related protein 0.0301 0.017 0.3629
Echinococcus granulosus tm gpcr rhodopsin 0.0264 0.0147 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0151 0.0077 0.041
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0089 0.0039 0.0402
Echinococcus multilocularis somatostatin receptor 0.0264 0.0147 0.0146
Brugia malayi MH1 domain containing protein 0.0122 0.0059 0.0289
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0264 0.0147 0.0146
Schistosoma mansoni thyroid hormone receptor 0.0072 0.0028 0.0062
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0264 0.0147 0.0146
Schistosoma mansoni peptidase Clp (S14 family) 0.0781 0.0466 0.1068
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1511 0.0916 1
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0139 0.0739
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0269 0.015 0.3199
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0139 0.0739
Echinococcus multilocularis acetylcholinesterase 0.0304 0.0171 0.017
Mycobacterium ulcerans carboxylesterase, LipT 0.0051 0.0015 0.0237
Brugia malayi photoreceptor-specific nuclear receptor 0.0313 0.0177 0.088
Schistosoma mansoni ferritin 0.0085 0.0036 0.0081
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0033 0.0345
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0072 0.0028 0.0137
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0238 0.0131 0.0697
Echinococcus multilocularis ferritin 0.0085 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.002
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0099 0.0045 0.0444
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0035 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0264 0.0147 0.073
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0058 0.0019 0.0165
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0033 0.0345
Brugia malayi hypothetical protein 0.0264 0.0147 0.0729
Loa Loa (eye worm) acetyltransferase 0.03 0.0169 0.0841
Trichomonas vaginalis PIKK family atypical protein kinase 0.0186 0.0098 0.0525
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.0242
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0072 0.0028 0.0135
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0218 0.0119 0.2429
Brugia malayi CXXC zinc finger family protein 0.0118 0.0056 0.0277
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0243 0.0134 0.2749
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0008 0.0043
Brugia malayi MH2 domain containing protein 0.0098 0.0044 0.0217
Schistosoma mansoni neuropeptide F-like receptor 0.0264 0.0147 0.0335
Echinococcus granulosus allatostatin A receptor 0.0264 0.0147 0.0146
Echinococcus granulosus rhodopsin orphan GPCR 0.0264 0.0147 0.0146
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0013 0.0012
Trypanosoma cruzi DNA polymerase kappa, putative 0.0079 0.0033 0.0336
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0106 0.0565
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0072 0.0028 0.0062
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Schistosoma mansoni coup transcription factor 0.0072 0.0028 0.0062
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0781 0.0466 1
Echinococcus granulosus mothers against decapentaplegic 6 0.0098 0.0044 0.0043
Loa Loa (eye worm) hypothetical protein 0.3267 0.2 1
Schistosoma mansoni neuropeptide F-like receptor 0.0264 0.0147 0.0335
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0339 0.0193 0.1031
Loa Loa (eye worm) transcription factor SMAD2 0.323 0.1978 0.9888
Schistosoma mansoni ap endonuclease 0.004 0.0008 0.0017
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Echinococcus granulosus rhodopsin orphan GPCR 0.0264 0.0147 0.0146
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0043 0.0011 0.001
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0264 0.0147 0.0335
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0002 0.0011
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0339 0.0193 0.2093
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0042 0.001 0.0044
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0212 0.0115 0.1243
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0781 0.0466 0.9805
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0264 0.0147 0.0146
Echinococcus multilocularis peptidase Clp (S14 family) 0.0512 0.03 0.0299
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.002
Schistosoma mansoni neuropeptide f receptor 76f 0.0264 0.0147 0.0335
Echinococcus granulosus thyroid hormone receptor alpha 0.0034 0.0005 0.0004
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0269 0.015 0.3071
Echinococcus granulosus neuropeptide Y receptor 0.0264 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0301 0.017 0.0845
Schistosoma mansoni hypothetical protein 0.0264 0.0147 0.0335
Schistosoma mansoni hypothetical protein 0.0111 0.0052 0.0117
Echinococcus multilocularis allatostatin A receptor 0.0264 0.0147 0.0146
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0124 0.006 0.032
Loa Loa (eye worm) nuclear factor I 0.0122 0.0059 0.0291
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0033 0.0345
Trichomonas vaginalis PIKK family atypical protein kinase 0.0186 0.0098 0.0525
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0073 0.0029 0.0153
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0048 0.0013 0.0286
Echinococcus multilocularis sex peptide receptor 0.0264 0.0147 0.0146
Schistosoma mansoni hypothetical protein 0.3811 0.2337 0.5366
Loa Loa (eye worm) heterochromatin protein 1 0.0076 0.003 0.0148
Echinococcus granulosus mixed lineage leukemia protein mll 0.0043 0.0011 0.001
Onchocerca volvulus 0.0051 0.0015 0.0077
Schistosoma mansoni hypothetical protein 0.0396 0.0228 0.0522
Brugia malayi Pre-SET motif family protein 0.0388 0.0223 0.1111
Schistosoma mansoni nuclear receptor 0.0034 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0339 0.0193 0.1031
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0781 0.0466 1
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0199 0.0107 0.2293
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0108 0.005 0.0538
Loa Loa (eye worm) hypothetical protein 0.0304 0.0171 0.0852
Schistosoma mansoni biogenic amine receptor 0.0264 0.0147 0.0335
Brugia malayi isocitrate dehydrogenase 0.0048 0.0013 0.0062
Schistosoma mansoni apoferritin-2 0.0085 0.0036 0.0081
Brugia malayi follicle stimulating hormone receptor 0.0264 0.0147 0.0729
Schistosoma mansoni amine GPCR 0.0264 0.0147 0.0335
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0225 0.0123 0.0611
Loa Loa (eye worm) hypothetical protein 0.0301 0.017 0.0845
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0008 0.0178
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0033 0.0004 0.0066
Loa Loa (eye worm) hypothetical protein 0.0031 0.0003 0.0011
Entamoeba histolytica hypothetical protein, conserved 0.0301 0.017 0.7345
Onchocerca volvulus 0.0264 0.0147 0.0779
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0264 0.0147 0.0335
Plasmodium vivax hypothetical protein, conserved 0.0301 0.017 0.3645
Schistosoma mansoni DNA polymerase eta 0.0105 0.0049 0.0109
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0058 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0008 0.0041
Brugia malayi RNA, U transporter 1 0.008 0.0033 0.0161
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.0242
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0034 0.0005 0.0019
Echinococcus multilocularis mothers against decapentaplegic 2 0.0098 0.0044 0.0043
Loa Loa (eye worm) hypothetical protein 0.0051 0.0015 0.0072
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0072 0.0028 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0072 0.0028 0.0135
Brugia malayi ImpB/MucB/SamB family protein 0.0079 0.0033 0.0158
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0033 0.0004 0.0091
Entamoeba histolytica hypothetical protein 0.0273 0.0152 0.6558
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0264 0.0147 0.0146
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0131 0.0064 0.0318
Echinococcus multilocularis zinc finger protein 0.0033 0.0004 0.0003
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0269 0.015 0.3154
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0053 0.0017 0.0036
Loa Loa (eye worm) hypothetical protein 0.008 0.0033 0.0163
Schistosoma mansoni serine-rich repeat protein 0.3811 0.2337 0.5366
Schistosoma mansoni Smad4 0.0098 0.0044 0.01
Brugia malayi Heterochromatin protein 1 0.0076 0.003 0.0147
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0781 0.0466 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0028 0.0137
Mycobacterium tuberculosis Probable reductase 0.0218 0.0119 0.2429
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0033 0.0004 0.0016
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0199 0.0107 0.2273
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0054 0.0017 0.0082
Loa Loa (eye worm) hypothetical protein 0.0301 0.017 0.0845
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0512 0.03 0.6277
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0004 0.0025
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Plasmodium vivax importin-beta 2, putative 0.0028 0.0001 0.0025
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0096 0.0043 0.082
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Echinococcus granulosus serine protein kinase ATM 0.0054 0.0017 0.0016
Brugia malayi von Willebrand factor type A domain containing protein 0.0301 0.017 0.0844
Trichomonas vaginalis ferritin, putative 0.0085 0.0036 0.0193
Schistosoma mansoni biogenic amine receptor 0.0264 0.0147 0.0335
Echinococcus multilocularis expressed protein 0.0085 0.0036 0.0035
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0072 0.0028 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0008 0.0041
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0058 0.0019 0.0413
Onchocerca volvulus 0.0034 0.0005 0.0019
Brugia malayi G protein-coupled receptor 0.0264 0.0147 0.0729
Echinococcus granulosus dnaJ subfamily B 0.1678 0.102 0.1019
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0072 0.0028 0.0027
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0099 0.0045 0.022
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.035 0.02 0.0993
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.0011 0.0023
Brugia malayi TAR-binding protein 0.0131 0.0064 0.0317
Loa Loa (eye worm) neuropeptide F receptor 0.0264 0.0147 0.073
Echinococcus granulosus rhodopsin orphan GPCR 0.0264 0.0147 0.0146
Schistosoma mansoni hypothetical protein 0.0035 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0264 0.0147 0.0146
Plasmodium vivax dynein-related AAA-type ATPase, putative 0.0301 0.017 0.3645
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0038 0.0007 0.0006
Echinococcus granulosus sodium channel protein 0.0136 0.0068 0.0067
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0072 0.0028 0.0027
Echinococcus multilocularis dna polymerase eta 0.0105 0.0049 0.0048
Plasmodium falciparum histone acetyltransferase GCN5 0.008 0.0033 0.0691
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0013 0.01
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0078 0.0032 0.0656
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0072 0.0028 0.0062
Brugia malayi Thioredoxin reductase 0.0096 0.0043 0.0209
Echinococcus granulosus orexin receptor type 2 0.0264 0.0147 0.0146
Plasmodium falciparum von Willebrand factor A domain-related protein 0.0301 0.017 0.3629
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0007 0.0031
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0013 0.0262
Echinococcus multilocularis snurportin 1 0.0301 0.017 0.0169
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Echinococcus granulosus acetylcholinesterase 0.0304 0.0171 0.017
Echinococcus granulosus biogenic amine 5HT receptor 0.0264 0.0147 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0186 0.0098 0.0525
Brugia malayi hypothetical protein 0.0194 0.0104 0.0514
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0072 0.0028 0.0027
Leishmania major mitochondrial DNA polymerase beta 0.1511 0.0916 1
Treponema pallidum 76K protein 0.0301 0.017 0.3586
Echinococcus granulosus mothers against decapentaplegic 2 0.0098 0.0044 0.0043
Echinococcus granulosus collagen alpha 1VII chain 0.0301 0.017 0.0169
Schistosoma mansoni voltage-gated potassium channel 0.0094 0.0042 0.0094
Onchocerca volvulus 0.0264 0.0147 0.0779
Giardia lamblia NADH oxidase lateral transfer candidate 0.0033 0.0004 0.0166
Echinococcus multilocularis isocitrate dehydrogenase 0.0048 0.0013 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.0242
Mycobacterium ulcerans hypothetical protein 0.0296 0.0167 0.3453
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.0242
Loa Loa (eye worm) hypothetical protein 0.0068 0.0026 0.0126
Brugia malayi hypothetical protein 0.0264 0.0147 0.0729
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0106 0.0565
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0013 0.0133
Schistosoma mansoni neuropeptide receptor 0.0264 0.0147 0.0335
Plasmodium falciparum ornithine aminotransferase 0.0042 0.001 0.0185
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0247 0.0136 0.5808
Echinococcus granulosus histone acetyltransferase KAT2B 0.009 0.0039 0.0038
Echinococcus multilocularis ecdysone induced protein 78C 0.0072 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0301 0.017 0.0845
Plasmodium vivax hypothetical protein, conserved 0.003 0.0002 0.0043
Echinococcus multilocularis neuropeptide FF receptor 2 0.0264 0.0147 0.0146
Echinococcus granulosus snurportin 1 0.0301 0.017 0.0169
Loa Loa (eye worm) TYRA-2 protein 0.0264 0.0147 0.073
Echinococcus granulosus neuropeptides capa receptor 0.0264 0.0147 0.0146
Brugia malayi Tachykinin-like peptides receptor 99D 0.0264 0.0147 0.0729
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0264 0.0147 0.0146
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0023 0.0234
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0264 0.0147 0.0146
Plasmodium falciparum thrombospondin-related anonymous protein 0.0301 0.017 0.3629
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0781 0.0466 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0004 0.0018
Brugia malayi ImpB/MucB/SamB family protein 0.0105 0.0049 0.0238
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0008 0.0045
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0111 0.0052 0.0255
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0715 0.0425 0.4632
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Echinococcus multilocularis tar DNA binding protein 0.0131 0.0064 0.0063
Schistosoma mansoni amine GPCR 0.0264 0.0147 0.0335
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0199 0.0107 0.2273
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0051 0.0015 0.0014
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0034 0.0005 0.0019
Brugia malayi nuclear receptor NHR-88 0.0072 0.0028 0.0135
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0000028905
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.0032
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0781 0.0466 0.0465
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0048 0.0013 0.0028
Loa Loa (eye worm) hypothetical protein 0.0048 0.0014 0.0064
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0045 0.0238
Brugia malayi hypothetical protein 0.0264 0.0147 0.0729
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0264 0.0147 0.0335
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0079 0.0033 0.0173
Onchocerca volvulus 0.0264 0.0147 0.0779
Schistosoma mansoni amine GPCR 0.0264 0.0147 0.0335
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0003 0.0005
Brugia malayi ecdysteroid receptor 0.0072 0.0028 0.0135
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0031 0.0003 0.001
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0781 0.0466 0.0465
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0264 0.0147 0.0146
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0001 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0023 0.0234
Toxoplasma gondii microneme protein MIC2 0.0301 0.017 0.3629
Leishmania major cathepsin L-like protease 0.0064 0.0023 0.0209
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0033 0.0345
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0085 0.0455
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0264 0.0147 0.0335
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0273 0.0152 0.6558
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0124 0.006 0.0136
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0045 0.0238
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.0242
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0264 0.0147 0.0335
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0008 0.0088
Echinococcus granulosus BC026374 protein S09 family 0.0051 0.0015 0.0014
Loa Loa (eye worm) TAR-binding protein 0.0131 0.0064 0.0318
Echinococcus granulosus chromobox protein 1 0.0076 0.003 0.0029
Echinococcus granulosus histone lysine methyltransferase setb 0.0404 0.0233 0.0232
Echinococcus multilocularis chromobox protein 1 0.0076 0.003 0.0029
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0008 0.0087
Brugia malayi Carboxylesterase family protein 0.0051 0.0015 0.0072
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0264 0.0147 0.0335
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0089 0.0039 0.041
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0058 0.0019 0.0198
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0023 0.0234
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0339 0.0193 0.1031
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0296 0.0167 0.3443
Trichomonas vaginalis PIKK family atypical protein kinase 0.0137 0.0069 0.0365
Schistosoma mansoni chromobox protein 0.0076 0.003 0.0067
Brugia malayi PHD-finger family protein 0.0038 0.0007 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0151 0.0077 0.041
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0078 0.0032 0.2211
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0296 0.0167 0.0889
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0033 0.0004 0.0066
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.001 0.0047
Schistosoma mansoni neuroligin 3 (S09 family) 0.0051 0.0015 0.0033
Echinococcus granulosus FTZ F1 alpha 0.0072 0.0028 0.0027
Brugia malayi GnHR receptor homolog 0.0264 0.0147 0.0729
Echinococcus multilocularis ornithine aminotransferase 0.0042 0.001 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0085 0.0455
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0058 0.0019 0.0389
Trichomonas vaginalis set domain proteins, putative 0.306 0.1873 1
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.008 0.0033 0.1136
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0054 0.0017 0.0411
Brugia malayi Probable ClpP-like protease 0.0781 0.0466 0.2325
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.008 0.0033 0.1136
Trichomonas vaginalis PIKK family atypical protein kinase 0.015 0.0076 0.0406
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0045 0.0238
Schistosoma mansoni opsin-like receptor 0.0264 0.0147 0.0335
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0218 0.0119 0.2429
Brugia malayi putative neuropeptide receptor NPR1 0.0264 0.0147 0.0729
Echinococcus granulosus neuropeptide FF receptor 2 0.0264 0.0147 0.0146
Schistosoma mansoni hypothetical protein 0.0264 0.0147 0.0335
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0048 0.0013 0.0262
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.0045 0.0468
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0264 0.0147 0.0335
Trypanosoma cruzi DNA polymerase eta, putative 0.005 0.0015 0.0141
Schistosoma mansoni ferritin light chain 0.0085 0.0036 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0005 0.0026
Echinococcus multilocularis neuropeptides capa receptor 0.0264 0.0147 0.0146
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0247 0.0136 0.0135
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0051 0.0015 0.0014
Onchocerca volvulus Serine\/threonine kinase homolog 0.0099 0.0045 0.0234
Brugia malayi von Willebrand factor type A domain containing protein 0.0301 0.017 0.0844
Echinococcus granulosus dro:myosuppressin receptor 0.0264 0.0147 0.0146
Echinococcus multilocularis rhodopsin orphan GPCR 0.0264 0.0147 0.0146
Brugia malayi hypothetical protein 0.0034 0.0005 0.0018
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0072 0.0028 0.0135
Echinococcus multilocularis rhodopsin orphan GPCR 0.0264 0.0147 0.0146
Brugia malayi hypothetical protein 0.0034 0.0005 0.0018
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0098 0.0044 0.0232
Treponema pallidum bacterioferrin (TpF1) 0.0085 0.0036 0.0694
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0264 0.0147 0.0335
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0072 0.0028 0.0027
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0005 0.0004
Echinococcus granulosus serotonin receptor 0.0264 0.0147 0.0146
Giardia lamblia Histone acetyltransferase GCN5 0.008 0.0033 0.2334
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0008 0.0041
Brugia malayi Isocitrate dehydrogenase 0.0048 0.0013 0.0062
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.009 0.0039 0.0818
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0033 0.0004 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0247 0.0136 0.0725
Toxoplasma gondii LsmAD domain-containing protein 0.0301 0.017 0.3625
Onchocerca volvulus 0.0249 0.0137 0.0729
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0005 0.0008
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0264 0.0147 0.0146
Echinococcus multilocularis rhodopsin orphan GPCR 0.0264 0.0147 0.0146
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0004 0.0025
Echinococcus multilocularis peregrin 0.0039 0.0008 0.0007
Brugia malayi serine/threonine-protein kinase plk-2 0.0099 0.0045 0.0219
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.03 0.0169 0.0168
Echinococcus granulosus peregrin 0.0039 0.0008 0.0007
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0388 0.0223 0.0511
Schistosoma mansoni RAR-like nuclear receptor 0.0072 0.0028 0.0062
Entamoeba histolytica hypothetical protein 0.0396 0.0228 1
Brugia malayi nuclear hormone receptor 0.0072 0.0028 0.0135
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0212 0.0115 0.1235
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0054 0.0017 0.0082
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0218 0.0119 0.2429
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0247 0.0136 0.031
Onchocerca volvulus 0.0264 0.0147 0.0779
Plasmodium vivax SET domain protein, putative 0.0388 0.0223 0.4792
Schistosoma mansoni myosin xvIII 0.0264 0.0147 0.0335
Echinococcus multilocularis thioredoxin glutathione reductase 0.0096 0.0043 0.0042
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0135 0.0067 0.0066
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0013 0.0012
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0034 0.0005 0.0004
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.0023 0.0234
Mycobacterium ulcerans hypothetical protein 0.0796 0.0475 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0264 0.0147 0.0335
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0004 0.0025
Schistosoma mansoni Smad4 0.0098 0.0044 0.01
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0051 0.0015 0.0033
Trichomonas vaginalis mercuric reductase, putative 0.0033 0.0004 0.0021
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0134 0.0067 0.0329
Brugia malayi von Willebrand factor type A domain containing protein 0.0301 0.017 0.0844
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0072 0.0028 0.0135
Echinococcus granulosus Nuclear hormone receptor HR96 0.0034 0.0005 0.0004
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0111 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0683 0.0406 0.2025
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0048 0.0013 0.0012
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0304 0.0171 0.0391
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0111 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0111 0.0052 0.0257
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0225 0.0123 0.0122
Echinococcus multilocularis g protein coupled receptor 0.0264 0.0147 0.0146
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0034 0.0005 0.0004
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0099 0.0045 0.0468
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0018 0.0179
Trypanosoma cruzi PAB1-binding protein , putative 0.0301 0.017 0.1833
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0072 0.0028 0.0135
Trypanosoma brucei DNA polymerase eta, putative 0.0105 0.0049 0.0519
Schistosoma mansoni gliotactin 0.0051 0.0015 0.0033
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0111 0.0052 0.0051
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0136 0.0068 0.0067
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0034 0.0005 0.0008
Brugia malayi acetyltransferase, GNAT family protein 0.03 0.0169 0.0839
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.002
Loa Loa (eye worm) CUTiclin family member 0.0301 0.017 0.0845
Loa Loa (eye worm) glutaminase 0.0544 0.0319 0.1594
Loa Loa (eye worm) carboxylesterase 0.0051 0.0015 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0137 0.0069 0.0365
Schistosoma mansoni neuropeptide receptor 0.0264 0.0147 0.0335
Loa Loa (eye worm) hypothetical protein 0.0301 0.017 0.0845
Schistosoma mansoni smad1 5 8 and 0.022 0.012 0.0273
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0396 0.0228 0.0227
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0058 0.0019 0.0189
Echinococcus granulosus g protein coupled receptor 0.0264 0.0147 0.0146
Schistosoma mansoni hypothetical protein 0.0111 0.0052 0.0117
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Trypanosoma cruzi DNA polymerase eta, putative 0.0105 0.0049 0.0511
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0013 0.0124
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0124 0.006 0.0296
Onchocerca volvulus 0.0051 0.0015 0.0077
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0124 0.006 0.2358
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0087 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Onchocerca volvulus 0.306 0.1873 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0264 0.0147 0.073
Loa Loa (eye worm) hypothetical protein 0.0301 0.017 0.0845
Onchocerca volvulus 0.0034 0.0005 0.0019
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0301 0.017 0.0845
Schistosoma mansoni bromodomain containing protein 0.0075 0.003 0.0067
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0058 0.0019 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0169 0.0088 0.0468
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.0044 0.0043
Onchocerca volvulus 0.0051 0.0015 0.0077
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0072 0.0028 0.0144
Onchocerca volvulus 0.0264 0.0147 0.0779
Leishmania major DNA polymerase eta, putative 0.005 0.0015 0.0117
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0139 0.0739
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0072 0.0028 0.0135
Loa Loa (eye worm) hypothetical protein 0.0072 0.0028 0.0137
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0089 0.0039 0.0402
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0264 0.0147 0.073
Loa Loa (eye worm) Smad1 0.022 0.012 0.0595
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0033 0.0345
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0042 0.001 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0138 0.0069 0.0365
Echinococcus granulosus GPCR family 2 0.0111 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0301 0.017 0.0845
Echinococcus multilocularis G protein coupled receptor 139 0.0264 0.0147 0.0146
Brugia malayi Pre-SET motif family protein 0.2689 0.1644 0.8217
Brugia malayi larval opioid receptor 0.0264 0.0147 0.0729
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0042 0.001 0.012
Onchocerca volvulus 0.0301 0.017 0.0901
Schistosoma mansoni tar DNA-binding protein 0.0131 0.0064 0.0145
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0264 0.0147 0.0335
Brugia malayi steroid hormone receptor 0.0072 0.0028 0.0135
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0072 0.0028 0.0135
Mycobacterium tuberculosis Conserved hypothetical protein 0.0079 0.0033 0.0605
Echinococcus granulosus expressed protein 0.0085 0.0036 0.0035
Schistosoma mansoni kinase 0.005 0.0015 0.0032
Loa Loa (eye worm) phosphatidylinositol 3 0.0247 0.0136 0.0676
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0008 0.0041
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0159 0.0082 0.335
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.0032
Loa Loa (eye worm) carboxylesterase 0.0051 0.0015 0.0074
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0264 0.0147 0.0146
Brugia malayi jmjC domain containing protein 0.0044 0.0011 0.0051
Schistosoma mansoni opsin-like receptor 0.0264 0.0147 0.0335
Schistosoma mansoni BC026374 protein (S09 family) 0.0051 0.0015 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.0242
Echinococcus granulosus smad 0.022 0.012 0.0119
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0124 0.006 0.0644
Trypanosoma cruzi DNA polymerase kappa, putative 0.0079 0.0033 0.0336
Schistosoma mansoni neuropeptide receptor 0.0264 0.0147 0.0335
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0072 0.0028 0.0135
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0134 0.0067 0.0151
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0085 0.0455
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0212 0.0115 0.1235
Echinococcus multilocularis nuclear receptor co repressor related (ncor) 0.0282 0.0158 0.0157
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0034 0.0005 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0072 0.0028 0.0137
Loa Loa (eye worm) hypothetical protein 0.0042 0.001 0.0046
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Echinococcus multilocularis collagen alpha 1(VII) chain 0.0301 0.017 0.0169
Echinococcus granulosus TGF beta signal transducer SmadC 0.022 0.012 0.0119
Leishmania major hypothetical protein, conserved 0.0301 0.017 0.1813
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0072 0.0028 0.0027
Schistosoma mansoni smad 0.0098 0.0044 0.01
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0124 0.006 0.0636
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.03 0.0169 0.0386
Trichomonas vaginalis PIKK family atypical protein kinase 0.0163 0.0085 0.0451
Echinococcus granulosus para nitrobenzyl esterase 0.0051 0.0015 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0247 0.0136 0.0725
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0339 0.0193 0.2093
Brugia malayi Zona pellucida-like domain containing protein 0.0301 0.017 0.0844
Schistosoma mansoni cellular tumor antigen P53 0.0683 0.0406 0.093
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0012 0.0062
Giardia lamblia Encystation-specific protease 0.0078 0.0032 0.2211
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0625 0.037 0.0847
Entamoeba histolytica hypothetical protein 0.0301 0.017 0.7345
Schistosoma mansoni Smad4 0.022 0.012 0.0273
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.002
Echinococcus multilocularis BC026374 protein (S09 family) 0.0051 0.0015 0.0014
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0072 0.0028 0.0062
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0072 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Schistosoma mansoni terminal deoxycytidyl transferase 0.0079 0.0033 0.0073
Brugia malayi Importin beta-1 subunit 0.0028 0.0001 0.0001
Echinococcus granulosus sex peptide receptor 0.0264 0.0147 0.0146
Mycobacterium ulcerans DNA polymerase IV 0.0079 0.0033 0.0605
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0058 0.0019 0.0018
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.0045 0.0468
Loa Loa (eye worm) hypothetical protein 0.0404 0.0233 0.1164
Echinococcus multilocularis g protein coupled receptor 0.0264 0.0147 0.0146
Brugia malayi hypothetical protein 0.0038 0.0007 0.0031
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0091 0.0484
Toxoplasma gondii cathepsin CPC2 0.0078 0.0032 0.0656
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Brugia malayi hypothetical protein 0.0264 0.0147 0.0729
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0124 0.006 0.2358
Plasmodium vivax glutathione reductase, putative 0.0096 0.0043 0.092
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0002 0.0018
Echinococcus multilocularis microtubule associated protein 2 0.3389 0.2076 0.2075
Schistosoma mansoni thyroid hormone receptor 0.0072 0.0028 0.0062
Echinococcus granulosus lysine specific demethylase 5A 0.0044 0.0011 0.001
Echinococcus multilocularis cpg binding protein 0.0126 0.0062 0.0061
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0054 0.0017 0.0016
Plasmodium falciparum glutathione reductase 0.0033 0.0004 0.0066
Entamoeba histolytica acetyltransferase, GNAT family 0.008 0.0033 0.1135
Echinococcus granulosus voltage gated potassium channel 0.0031 0.0003 0.0002
Echinococcus multilocularis Smad4 0.022 0.012 0.0119
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.002
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0008 0.0007
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0054 0.0017 0.0038
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0034 0.0005 0.0008
Echinococcus multilocularis thyroid hormone receptor alpha 0.0072 0.0028 0.0027
Brugia malayi putative neuropeptide receptor 0.0264 0.0147 0.0729
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0014 0.0073
Schistosoma mansoni cpg binding protein 0.0126 0.0062 0.014
Toxoplasma gondii FATC domain-containing protein 0.0054 0.0017 0.0348
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0033 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0072 0.0028 0.0137
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0264 0.0147 0.0335
Loa Loa (eye worm) hypothetical protein 0.0051 0.0015 0.0074
Loa Loa (eye worm) von Willebrand factor type A domain-containing protein 0.0301 0.017 0.0845
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0218 0.0119 0.2386
Schistosoma mansoni hypothetical protein 0.0301 0.017 0.0388
Trichomonas vaginalis PIKK family atypical protein kinase 0.0186 0.0098 0.0525
Schistosoma mansoni voltage-gated potassium channel 0.0094 0.0042 0.0094
Mycobacterium ulcerans bacterioferritin BfrB 0.0085 0.0036 0.0681
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.009 0.0039 0.0208
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0045 0.0238
Brugia malayi Carboxylesterase family protein 0.0304 0.0171 0.0851
Echinococcus granulosus 7TM GPCR rhodopsin 0.0264 0.0147 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0002 0.0009
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0008 0.0087
Echinococcus multilocularis voltage gated potassium channel 0.0031 0.0003 0.0002
Brugia malayi Bromodomain containing protein 0.0039 0.0008 0.0035
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.04 0.0231 0.0528
Brugia malayi Nuclear hormone receptor E75 0.0034 0.0005 0.0018
Schistosoma mansoni biogenic amine (5HT) receptor 0.0264 0.0147 0.0335
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0078 0.0032 0.2211
Echinococcus granulosus microtubule associated protein 2 0.3389 0.2076 0.2075
Loa Loa (eye worm) CUTiclin-Like family member 0.0301 0.017 0.0845
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0301 0.017 0.0844
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0004 0.0025
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0005 0.0004
Schistosoma mansoni transcription factor LCR-F1 0.0396 0.0228 0.0522
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0038 0.0007 0.0032
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0087 0.0037 0.0036
Echinococcus granulosus neuropeptide receptor 0.0264 0.0147 0.0146
Loa Loa (eye worm) carboxylesterase 0.0304 0.0171 0.0852
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0043 0.0011 0.001
Toxoplasma gondii thioredoxin reductase 0.0096 0.0043 0.0897
Onchocerca volvulus 0.04 0.0231 0.1228
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0781 0.0466 1
Brugia malayi RNA recognition motif domain containing protein 0.0131 0.0064 0.0317
Toxoplasma gondii preprocathepsin c precursor, putative 0.0199 0.0107 0.2273
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0034 0.0005 0.0004
Onchocerca volvulus 0.0264 0.0147 0.0779
Brugia malayi hypothetical protein 0.0038 0.0007 0.0031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.0242
Trypanosoma cruzi target of rapamycin kinase 3 0.0198 0.0106 0.1139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0089 0.0039 0.0206
Onchocerca volvulus Alhambra homolog 0.003 0.0002 0.0005
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0781 0.0466 0.9805
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0028 0.0001 0.0002
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0043 0.0011 0.001
Entamoeba histolytica hypothetical protein 0.0396 0.0228 1
Echinococcus multilocularis fmrfamide receptor 0.0264 0.0147 0.0146
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0058 0.0019 0.0189
Schistosoma mansoni acetylcholinesterase 0.0051 0.0015 0.0033
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0008 0.0154
Onchocerca volvulus 0.0301 0.017 0.0901
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0033 0.0004 0.0003
Brugia malayi von Willebrand factor type A domain containing protein 0.0301 0.017 0.0844
Brugia malayi mothers against decapentaplegic homolog 3 0.0098 0.0044 0.0217
Echinococcus granulosus Nuclear hormone receptor HR96 0.0034 0.0005 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0072 0.0028 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0089 0.0039 0.0206
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0296 0.0167 0.3453
Brugia malayi MH2 domain containing protein 0.323 0.1978 0.9888
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0124 0.006 0.032
Loa Loa (eye worm) hypothetical protein 0.0076 0.0031 0.0151
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0004 0.0033
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0031 0.0069
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Schistosoma mansoni hypothetical protein 0.1556 0.0945 0.2168
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0004 0.0025
Trypanosoma brucei DNA polymerase IV, putative 0.0079 0.0033 0.0345
Mycobacterium ulcerans glutaminase 0.0544 0.0319 0.6695
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.001 0.0052
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0099 0.0045 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0000028905
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0042 0.001 0.012
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.2689 0.1644 0.8217
Schistosoma mansoni hypothetical protein 0.0264 0.0147 0.0335
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.0242
Schistosoma mansoni glutaminase 0.0544 0.0319 0.0732
Schistosoma mansoni hypothetical protein 0.0111 0.0052 0.0117
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0031 0.0003 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0186 0.0098 0.0525
Brugia malayi hypothetical protein 0.0633 0.0374 0.1867
Brugia malayi Calcitonin receptor-like protein seb-1 0.035 0.02 0.0993
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0225 0.0123 0.0122
Echinococcus multilocularis rhodopsin orphan GPCR 0.0264 0.0147 0.0146
Onchocerca volvulus 0.0072 0.0028 0.0144
Echinococcus granulosus alpha 1A adrenergic receptor 0.0264 0.0147 0.0146
Echinococcus granulosus neuropeptide receptor 0.0264 0.0147 0.0146
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0002 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0004 0.0025
Brugia malayi PHD-finger family protein 0.003 0.0002 0.0005
Echinococcus granulosus tumor protein p63 0.4669 0.2866 0.2866
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0198 0.0106 0.1147
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0009 0.0008
Echinococcus granulosus dna polymerase kappa 0.0079 0.0033 0.0032
Echinococcus multilocularis neuroligin 0.0051 0.0015 0.0014
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.7078 0.4353 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0264 0.0147 0.0146
Loa Loa (eye worm) phosphatidylinositol 3 0.0099 0.0045 0.022
Echinococcus granulosus acetylcholinesterase 0.0304 0.0171 0.017
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Onchocerca volvulus 0.0683 0.0406 0.2162
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0134 0.0067 0.0066
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0008 0.0038
Loa Loa (eye worm) MH1 domain-containing protein 0.0098 0.0044 0.0219
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0247 0.0136 0.1473
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1402 0.085 0.195
Onchocerca volvulus 0.0118 0.0056 0.0296
Echinococcus multilocularis rhodopsin orphan GPCR 0.0264 0.0147 0.0146
Echinococcus granulosus chromobox protein 1 0.0076 0.003 0.0029
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0212 0.0115 0.1235
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0072 0.0028 0.0027
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0264 0.0147 0.0146
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0134 0.0067 0.0151
Schistosoma mansoni retinoic acid receptor RXR 0.0072 0.0028 0.0062
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0008 0.0041
Entamoeba histolytica hypothetical protein 0.0396 0.0228 1
Entamoeba histolytica hypothetical protein 0.0396 0.0228 1
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Toxoplasma gondii exonuclease III APE 0.004 0.0008 0.0154
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0625 0.037 0.0369
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0085 0.0455
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0072 0.0028 0.0137
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0085 0.0455
Brugia malayi FAT domain containing protein 0.0035 0.0005 0.0021
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0134 0.0067 0.033
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0072 0.0028 0.0062
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0042 0.001 0.0118
Trichomonas vaginalis chromobox protein, putative 0.0076 0.003 0.0161
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0004 0.0025
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0054 0.0017 0.0168
Schistosoma mansoni neuropeptide receptor 0.0264 0.0147 0.0335
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0238 0.0131 0.0697
Brugia malayi MH2 domain containing protein 0.022 0.012 0.0593
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0029 0.0153
Brugia malayi nuclear hormone receptor family member odr-7 0.0034 0.0005 0.0018
Echinococcus multilocularis mothers against decapentaplegic 5 0.022 0.012 0.0119
Brugia malayi MH1 domain containing protein 0.022 0.012 0.0593
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0004 0.0025
Loa Loa (eye worm) hypothetical protein 0.0072 0.0028 0.0137
Mycobacterium tuberculosis Probable dehydrogenase 0.0218 0.0119 0.2429
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0051 0.0015 0.0033
Plasmodium falciparum glutathione reductase 0.0096 0.0043 0.0897
Plasmodium falciparum thioredoxin reductase 0.0096 0.0043 0.0897
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Loa Loa (eye worm) isocitrate dehydrogenase 0.0048 0.0013 0.0063
Schistosoma mansoni alpha-1 adrenergic receptor 0.0264 0.0147 0.0335
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0089 0.0039 0.0189
Loa Loa (eye worm) hypothetical protein 0.0122 0.0059 0.0291
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0000028905
Brugia malayi hypothetical protein 0.0264 0.0147 0.0729
Echinococcus multilocularis rhodopsin orphan GPCR 0.0264 0.0147 0.0146
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0243 0.0134 0.2749
Plasmodium vivax histone acetyltransferase GCN5, putative 0.009 0.0039 0.0841
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0259 0.0144 0.1548
Echinococcus multilocularis FTZ F1 alpha 0.0072 0.0028 0.0027
Trypanosoma brucei DNA polymerase IV, putative 0.0079 0.0033 0.0345
Loa Loa (eye worm) MH2 domain-containing protein 0.0098 0.0044 0.0219
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0264 0.0147 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0138 0.0069 0.0365
Plasmodium falciparum phd finger protein, putative 0.003 0.0002 0.0018
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0008 0.0036
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0079 0.0033 0.0032
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0021 0.0104
Brugia malayi Bromodomain containing protein 0.0044 0.0011 0.0051
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0072 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.006 0.002 0.0099
Loa Loa (eye worm) acetylcholinesterase 1 0.0304 0.0171 0.0852
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0058 0.0019 0.0498
Echinococcus granulosus voltage dependent calcium channel subunit 0.7379 0.4539 0.4539
Echinococcus granulosus cpg binding protein 0.0126 0.0062 0.0061
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.002
Loa Loa (eye worm) hypothetical protein 0.003 0.0002 0.0007
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0255 0.0141 0.0322
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0135 0.0067 0.0066
Loa Loa (eye worm) hypothetical protein 0.0072 0.0028 0.0137
Plasmodium vivax ornithine aminotransferase, putative 0.0042 0.001 0.021
Brugia malayi Melatonin receptor type 1A 0.0264 0.0147 0.0729
Brugia malayi Cache domain containing protein 0.3267 0.2 1
Brugia malayi hypothetical protein 0.0264 0.0147 0.0729
Brugia malayi MH1 domain containing protein 0.022 0.012 0.0593
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0031 0.0003 0.0002
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0058 0.0019 0.0102
Loa Loa (eye worm) neuropeptide F receptor 0.0264 0.0147 0.073
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0058 0.0019 0.0498
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0051 0.0015 0.0237
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0087 0.0037 0.0183
Onchocerca volvulus 0.0051 0.0015 0.0077
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0404 0.0233 0.0534
Plasmodium falciparum ataxin-2 like protein, putative 0.0301 0.017 0.3625
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0002 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0072 0.0028 0.0135
Loa Loa (eye worm) MH2 domain-containing protein 0.323 0.1978 0.9888
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0058 0.0019 0.0389
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0125 0.0061 0.0324
Brugia malayi Immunoglobulin I-set domain containing protein 0.0301 0.017 0.0844
Echinococcus granulosus peptide allatostatin:somatostatin 0.0264 0.0147 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0017 0.0091
Loa Loa (eye worm) hypothetical protein 0.0054 0.0017 0.0083
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.002
Loa Loa (eye worm) hypothetical protein 0.0301 0.017 0.0845
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0247 0.0136 0.1473
Echinococcus granulosus nuclear receptor co repressor related ncor 0.0282 0.0158 0.0157
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0781 0.0466 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0028 0.0137
Brugia malayi Carboxylesterase family protein 0.0304 0.0171 0.0851
Schistosoma mansoni hypothetical protein 0.003 0.0002 0.0002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0072 0.0028 0.0135
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0264 0.0147 0.0729
Echinococcus granulosus ecdysone induced protein 78C 0.0072 0.0028 0.0027
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0264 0.0147 0.073
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0085 0.0036 0.0581
Brugia malayi Dopamine receptor 0.0264 0.0147 0.0729
Echinococcus granulosus histone acetyltransferase KAT2B 0.0289 0.0162 0.0161
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0625 0.037 0.0369
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0087 0.0037 0.0181
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0781 0.0466 1
Echinococcus granulosus peptidase Clp S14 family 0.0512 0.03 0.0299
Echinococcus multilocularis Aminotransferase class III 0.0042 0.001 0.0009
Brugia malayi sulfakinin receptor protein 0.0264 0.0147 0.0729
Schistosoma mansoni hypothetical protein 0.0264 0.0147 0.0335
Onchocerca volvulus 0.0301 0.017 0.0901
Echinococcus multilocularis ornithine aminotransferase 0.0042 0.001 0.0009
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0008 0.0471
Loa Loa (eye worm) pax transcription factor protein 2 0.0249 0.0137 0.0684
Loa Loa (eye worm) latrophilin receptor protein 2 0.0111 0.0052 0.0257
Trypanosoma brucei PAB1-binding protein , putative 0.0301 0.017 0.184
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0264 0.0147 0.0146
Echinococcus multilocularis serine protein kinase ATM 0.0054 0.0017 0.0016
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0042 0.001 0.0118
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0199 0.0107 0.2293
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0034 0.0005 0.0004
Mycobacterium ulcerans bacterioferritin BfrA 0.0085 0.0036 0.0681
Echinococcus granulosus geminin 0.1556 0.0945 0.0944
Schistosoma mansoni tar DNA-binding protein 0.0131 0.0064 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0247 0.0136 0.0725
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0048 0.0013 0.0193
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0008 0.0069
Brugia malayi Bromodomain containing protein 0.0087 0.0037 0.0181
Echinococcus multilocularis Zinc finger, PHD finger 0.0058 0.0019 0.0018
Brugia malayi orphan nuclear receptor NR2E1 0.0034 0.0005 0.0018
Loa Loa (eye worm) MH2 domain-containing protein 0.022 0.012 0.0595
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0264 0.0147 0.0335
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Schistosoma mansoni hypothetical protein 0.0135 0.0067 0.0152
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0051 0.0015 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0000028905
Echinococcus multilocularis voltage dependent calcium channel subunit 1.6224 1 1
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0091 0.004 0.2836
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0004 0.0033
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0122 0.0059 0.063
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0085 0.0036 0.0694
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0008 0.0088
Onchocerca volvulus 0.0264 0.0147 0.0779
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0054 0.0017 0.0168
Loa Loa (eye worm) hypothetical protein 0.0051 0.0015 0.0074
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0008 0.0041
Brugia malayi hypothetical protein 0.0264 0.0147 0.0729
Echinococcus granulosus neuropeptides capa receptor 0.0264 0.0147 0.0146
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0072 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0313 0.0177 0.0882
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0139 0.0739
Loa Loa (eye worm) hypothetical protein 0.0051 0.0015 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0186 0.0098 0.0525
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0264 0.0147 0.0146
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0134 0.0067 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0072 0.0028 0.0135
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.0032
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0012 0.0062
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0042 0.001 0.002
Schistosoma mansoni ferritin 0.0085 0.0036 0.0081
Leishmania major DNA polymerase kappa, putative 0.0079 0.0033 0.0312
Schistosoma mansoni hypothetical protein 0.0111 0.0052 0.0117
Schistosoma mansoni tar DNA-binding protein 0.0131 0.0064 0.0145
Trypanosoma brucei trypanothione reductase 0.0096 0.0043 0.0456
Echinococcus granulosus 7tm_1 domain containing protein 0.0264 0.0147 0.0146
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0264 0.0147 0.0335
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0218 0.0119 0.2429
Entamoeba histolytica hypothetical protein, conserved 0.0301 0.017 0.7345
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0085 0.0455
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0017 0.0091
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.002
Echinococcus multilocularis geminin 0.1556 0.0945 0.0944
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0008 0.0041
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0008 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0033 0.0345
Onchocerca volvulus 0.0301 0.017 0.0901
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0388 0.0223 0.0222
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0264 0.0147 0.0146
Brugia malayi MH1 domain containing protein 0.0122 0.0059 0.0289
Echinococcus granulosus dna polymerase eta 0.0105 0.0049 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0033 0.0345
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0018 0.0179
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0002 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0002 0.0009
Schistosoma mansoni growth hormone secretagogue receptor 0.0264 0.0147 0.0335
Toxoplasma gondii cathepsin CPC1 0.0199 0.0107 0.2273
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0301 0.017 0.0845
Echinococcus granulosus biogenic amine 5HT receptor 0.0264 0.0147 0.0146
Brugia malayi hypothetical protein 0.0051 0.0015 0.0072
Echinococcus multilocularis fmrfamide receptor 0.0264 0.0147 0.0146
Entamoeba histolytica serine/threonine protein kinase, putative 0.0099 0.0045 0.1658
Onchocerca volvulus 0.0033 0.0004 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0186 0.0098 0.0525
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0264 0.0147 0.0335
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0011 0.0052
Schistosoma mansoni cpg binding protein 0.0126 0.0062 0.014
Echinococcus multilocularis serotonin receptor 0.0264 0.0147 0.0146
Echinococcus granulosus tachykinin peptides receptor 99D 0.0264 0.0147 0.0146
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0078 0.0032 0.0679
Leishmania major cathepsin L-like protease 0.0064 0.0023 0.0209
Echinococcus multilocularis GPCR, family 2 0.0111 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Onchocerca volvulus Protein ultraspiracle homolog 0.0072 0.0028 0.0144
Onchocerca volvulus Bile acid receptor homolog 0.0072 0.0028 0.0144
Brugia malayi SET domain containing protein 0.0029 0.0002 0.0004
Toxoplasma gondii NADPH-glutathione reductase 0.0033 0.0004 0.0066
Schistosoma mansoni chromobox protein 0.0076 0.003 0.0067
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0079 0.0033 0.0032
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0 0.0000000000075505
Echinococcus multilocularis neuropeptide receptor 0.0264 0.0147 0.0146
Echinococcus granulosus fmrfamide receptor 0.0264 0.0147 0.0146
Brugia malayi hypothetical protein 0.0264 0.0147 0.0729
Leishmania major phosphatidylinositol 3-kinase, putative 0.0089 0.0039 0.0378
Onchocerca volvulus 0.0301 0.017 0.0901
Onchocerca volvulus 0.0264 0.0147 0.0779
Echinococcus multilocularis dro:myosuppressin receptor 0.0264 0.0147 0.0146
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0172 0.009 0.6553
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0008 0.0069
Loa Loa (eye worm) nuclear receptor NHR-67 0.0034 0.0005 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0264 0.0147 0.0335
Schistosoma mansoni zinc finger protein 0.0034 0.0005 0.0008
Echinococcus granulosus ferritin 0.0085 0.0036 0.0035
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0042 0.001 0.0185
Echinococcus granulosus carboxylesterase 5A 0.0304 0.0171 0.017
Brugia malayi G-protein coupled receptor 0.0264 0.0147 0.0729
Trypanosoma brucei unspecified product 0.0055 0.0018 0.0179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0106 0.0565
Loa Loa (eye worm) pigment dispersing factor receptor c 0.035 0.02 0.0994
Brugia malayi tailless protein 0.0034 0.0005 0.0018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0404 0.0233 0.0534
Mycobacterium tuberculosis Conserved hypothetical protein 0.0796 0.0475 1
Echinococcus multilocularis carboxylesterase 5A 0.0304 0.0171 0.017
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0042 0.001 0.0118
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0089 0.0039 0.0087
Trypanosoma brucei unspecified product 0.0055 0.0018 0.0179
Onchocerca volvulus 0.0264 0.0147 0.0779
Brugia malayi nuclear receptor NHR-67 0.0034 0.0005 0.0018
Brugia malayi hypothetical protein 0.0264 0.0147 0.0729
Onchocerca volvulus 0.0264 0.0147 0.0779
Echinococcus granulosus rhodopsin orphan GPCR 0.0264 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0264 0.0147 0.0335
Brugia malayi hypothetical protein 0.0396 0.0228 0.1136
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0058 0.0019 0.0389
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Toxoplasma gondii non-specific serine/threonine protein kinase 0.006 0.002 0.0416
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0004 0.0025
Echinococcus multilocularis orexin receptor type 2 0.0264 0.0147 0.0146
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0124 0.006 0.032
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0028 0.0027
Brugia malayi hypothetical protein 0.0301 0.017 0.0844
Schistosoma mansoni smad1 5 8 and 0.022 0.012 0.0273
Echinococcus granulosus g-protein coupled receptor 0.0264 0.0147 0.0146
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0715 0.0425 0.4628
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0264 0.0147 0.0335
Schistosoma mansoni ferritin 0.0085 0.0036 0.0081
Brugia malayi conserved hypotetical protein 0.0034 0.0005 0.0018
Brugia malayi von Willebrand factor type A domain containing protein 0.0301 0.017 0.0844
Echinococcus multilocularis G-protein coupled receptor, putative 0.0264 0.0147 0.0146
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0079 0.0033 0.0073
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.0001 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0131 0.0064 0.0145
Loa Loa (eye worm) steroid hormone receptor 0.0072 0.0028 0.0137
Trichomonas vaginalis glutathione reductase, putative 0.0033 0.0004 0.0021
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0072 0.0028 0.0137
Trichomonas vaginalis glutaminase, putative 0.0544 0.0319 0.1704
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0058 0.0019 0.0091
Brugia malayi Dopamine receptor protein 1 0.0264 0.0147 0.0729
Trichomonas vaginalis PIKK family atypical protein kinase 0.0089 0.0039 0.0206
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0247 0.0136 0.1444
Plasmodium vivax von Willebrand factor A domain-related protein, putative 0.0301 0.017 0.3645
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.0242
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0045 0.0238
Trichomonas vaginalis spcc417.12 protein, putative 0.0051 0.0015 0.0081
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0072 0.0028 0.0027
Echinococcus multilocularis g-protein coupled receptor 0.0264 0.0147 0.0146
Brugia malayi glutaminase DH11.1 0.0544 0.0319 0.1592
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0264 0.0147 0.0146
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0199 0.0107 0.0243
Brugia malayi von Willebrand factor type A domain containing protein 0.0301 0.017 0.0844
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0015 0.0141
Brugia malayi neuropeptide F receptor 0.0264 0.0147 0.0729
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0079 0.0033 0.016
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0045 0.0238
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0042 0.001 0.0118
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0089 0.0039 0.0038
Schistosoma mansoni hypothetical protein 0.1556 0.0945 0.2168
Schistosoma mansoni hypothetical protein 0.0239 0.0131 0.0299
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0198 0.0106 0.1117
Echinococcus multilocularis dna polymerase kappa 0.0079 0.0033 0.0032
Brugia malayi von Willebrand Factor 0.0301 0.017 0.0844
Echinococcus multilocularis neuropeptide receptor A26 0.0264 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.003 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0114 0.0054 0.0268
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.0032
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0034 0.0005 0.0018
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0058 0.0019 0.0042
Brugia malayi nuclear receptor NHR-88 0.0034 0.0005 0.0018
Loa Loa (eye worm) hypothetical protein 0.0028 0.0001 0.0002
Echinococcus granulosus tm gpcr rhodopsin 0.0264 0.0147 0.0146
Loa Loa (eye worm) glutathione reductase 0.0096 0.0043 0.0211
Plasmodium vivax circumsporozoite- and TRAP-related protein, putative 0.0301 0.017 0.3645
Loa Loa (eye worm) hypothetical protein 0.0301 0.017 0.0845
Echinococcus granulosus nuclear receptor nhr 48 0.0034 0.0005 0.0004
Loa Loa (eye worm) G-protein coupled receptor 0.0264 0.0147 0.073
Loa Loa (eye worm) RNA binding protein 0.0131 0.0064 0.0318
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0264 0.0147 0.0729
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0264 0.0147 0.0146
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0034 0.0005 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0106 0.0565
Schistosoma mansoni zinc finger protein 0.0033 0.0004 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0000028905
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0072 0.0028 0.0135
Echinococcus granulosus Smad4 0.022 0.012 0.0119
Echinococcus granulosus zinc finger protein 0.0033 0.0004 0.0003
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.3568 0.2186 0.5021
Onchocerca volvulus Glucosylceramidase homolog 0.0165 0.0085 0.0451
Echinococcus granulosus rhodopsin orphan GPCR 0.0264 0.0147 0.0146
Trypanosoma cruzi DNA polymerase kappa, putative 0.0079 0.0033 0.0336
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0048 0.0013 0.0012
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0008 0.0043
Echinococcus granulosus tar DNA binding protein 0.0131 0.0064 0.0063
Plasmodium vivax thrombospondin-related anonymous protein 0.0301 0.017 0.3645
Brugia malayi F/Y-rich N-terminus family protein 0.0062 0.0022 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0212 0.0115 0.0611
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0008 0.0078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0023 0.0242
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0264 0.0147 0.0146
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0005 0.0008
Schistosoma mansoni microtubule-associated protein tau 0.3389 0.2076 0.4767
Schistosoma mansoni nuclear receptor 0.0034 0.0005 0.0008
Loa Loa (eye worm) phosphatidylinositol 3 0.0559 0.0329 0.1641
Trichomonas vaginalis PIKK family atypical protein kinase 0.0151 0.0077 0.041
Brugia malayi glutathione reductase 0.0096 0.0043 0.0209
Onchocerca volvulus 0.0264 0.0147 0.0779
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Schistosoma mansoni apoferritin-2 0.0085 0.0036 0.0081
Onchocerca volvulus 0.0264 0.0147 0.0779
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0013 0.0262
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0000028905
Mycobacterium ulcerans acetylornithine aminotransferase 0.0042 0.001 0.0118
Brugia malayi Carboxylesterase family protein 0.0051 0.0015 0.0072
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Onchocerca volvulus 0.0264 0.0147 0.0779
Loa Loa (eye worm) G-protein coupled receptor 0.0264 0.0147 0.073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0138 0.0069 0.0365
Echinococcus granulosus neuropeptide s receptor 0.0264 0.0147 0.0146
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0085 0.0036 0.0681
Echinococcus granulosus neuropeptide receptor A26 0.0264 0.0147 0.0146
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0269 0.015 0.3217
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0038 0.0007 0.0014
Onchocerca volvulus 0.0264 0.0147 0.0779
Trypanosoma brucei DNA polymerase IV, putative 0.0079 0.0033 0.0345
Loa Loa (eye worm) DR-78 0.0034 0.0005 0.002
Schistosoma mansoni smad1 5 8 and 0.022 0.012 0.0273
Leishmania major cathepsin L-like protease 0.0064 0.0023 0.0209
Echinococcus multilocularis neuropeptide Y receptor 0.0264 0.0147 0.0146
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0033 0.0345
Entamoeba histolytica protein kinase rad3, putative 0.0054 0.0017 0.0411
Loa Loa (eye worm) hypothetical protein 0.0633 0.0374 0.1868
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1511 0.0916 1
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0296 0.0167 0.3453
Echinococcus multilocularis voltage dependent calcium channel subunit 0.7379 0.4539 0.4539
Schistosoma mansoni adenoreceptor 0.0264 0.0147 0.0335
Echinococcus granulosus neuroligin 0.0051 0.0015 0.0014
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0042 0.001 0.0118
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0264 0.0147 0.0729
Loa Loa (eye worm) hypothetical protein 0.0781 0.0466 0.2326
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0264 0.0147 0.0335
Loa Loa (eye worm) hypothetical protein 0.035 0.02 0.0994
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0251 0.0139 0.069
Schistosoma mansoni histamine h1 receptor 0.0264 0.0147 0.0335
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0033 0.0345
Loa Loa (eye worm) hypothetical protein 0.0301 0.017 0.0845
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0715 0.0425 0.4614
Loa Loa (eye worm) melatonin receptor type 1A 0.0264 0.0147 0.073
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.0011 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0089 0.0039 0.0206
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0072 0.0028 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0137 0.0069 0.0365
Giardia lamblia Kinase, PLK 0.0099 0.0045 0.3191
Schistosoma mansoni fkbp-rapamycin associated protein 0.0054 0.0017 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0198 0.0106 0.0565
Brugia malayi Pax transcription factor protein 2 0.0249 0.0137 0.0682
Giardia lamblia DINP protein human, muc B family 0.0079 0.0033 0.2292
Onchocerca volvulus 0.0633 0.0374 0.1994
Treponema pallidum hypothetical protein 0.0301 0.017 0.3586
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0045 0.0238
Loa Loa (eye worm) hypothetical protein 0.0047 0.0013 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.006 0.002 0.0108
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0058 0.0019 0.0018
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0247 0.0136 0.0675
Schistosoma mansoni biogenic amine (5HT) receptor 0.0264 0.0147 0.0335
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0035 0.0005 0.0004
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0079 0.0033 0.0312
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0033 0.0004 0.0033
Brugia malayi chromobox protein homolog 3 0.0042 0.001 0.0044
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0099 0.0045 0.0044
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0136 0.0068 0.0699
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0051 0.0015 0.0237
Loa Loa (eye worm) phosphatidylinositol 3 0.0089 0.0039 0.019
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0073 0.0029 0.0153
Echinococcus granulosus mothers against decapentaplegic 5 0.022 0.012 0.0119
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0264 0.0147 0.0729
Echinococcus multilocularis TGF beta signal transducer SmadC 0.022 0.012 0.0119
Echinococcus granulosus rhodopsin orphan GPCR 0.0264 0.0147 0.0146
Echinococcus multilocularis smad 0.022 0.012 0.0119
Schistosoma mansoni nuclear receptor nhr-48 0.0034 0.0005 0.0008
Echinococcus multilocularis tumor protein p63 0.4669 0.2866 0.2866
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0058 0.0019 0.0102
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0059 0.002 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0027 0 0.0000028905
Loa Loa (eye worm) histone methyltransferase 0.0051 0.0015 0.0072
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0033 0.0004 0.0003
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0042 0.001 0.0118
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Loa Loa (eye worm) MH1 domain-containing protein 0.022 0.012 0.0595
Onchocerca volvulus 0.0301 0.017 0.0901
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0247 0.0136 0.1465
Echinococcus multilocularis g protein coupled receptor 0.0264 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0301 0.017 0.0845
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0371 0.0213 0.0212
Schistosoma mansoni ferritin 0.0085 0.0036 0.0081
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0247 0.0136 0.5808
Echinococcus multilocularis neuropeptide Y receptor 0.0264 0.0147 0.0146
Entamoeba histolytica deoxycytidyl transferase, putative 0.0079 0.0033 0.111
Echinococcus granulosus g protein coupled receptor 0.0264 0.0147 0.0146
Schistosoma mansoni cpg binding protein 0.0118 0.0056 0.0127
Brugia malayi ecdysone receptor 0.0034 0.0005 0.0018
Leishmania major phosphatidylinositol 3-kinase, putative 0.0058 0.0019 0.0165
Toxoplasma gondii ImpB/MucB/SamB family protein 0.005 0.0015 0.0295
Brugia malayi RE15519p 0.0264 0.0147 0.0729
Echinococcus granulosus Aminotransferase class III 0.0042 0.001 0.0009
Onchocerca volvulus 0.0264 0.0147 0.0779
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0072 0.0028 0.0062
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.009 0.0039 0.0818
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0085 0.0455
Loa Loa (eye worm) hypothetical protein 0.0239 0.0131 0.0653
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0002 0.0002
Schistosoma mansoni nuclear hormone receptor 0.0072 0.0028 0.0062
Loa Loa (eye worm) von Willebrand factor domain-containing protein 0.0301 0.017 0.0845
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0388 0.0223 0.4779
Echinococcus granulosus thioredoxin glutathione reductase 0.0096 0.0043 0.0042
Brugia malayi G protein-coupled receptor F59B2.13 0.0264 0.0147 0.0729
Brugia malayi Dopamine receptor protein 2 0.0264 0.0147 0.0729
Echinococcus granulosus tm gpcr rhodopsin 0.0264 0.0147 0.0146
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0286 0.016 0.0795
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0033 0.0004 0.0066
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0051 0.0015 0.0033
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0051 0.0015 0.0014
Onchocerca volvulus 0.0264 0.0147 0.0779
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Loa Loa (eye worm) hypothetical protein 0.0301 0.017 0.0845
Trypanosoma cruzi DNA polymerase kappa, putative 0.0079 0.0033 0.0336
Onchocerca volvulus 0.0264 0.0147 0.0779
Brugia malayi Zona pellucida-like domain containing protein 0.0301 0.017 0.0844
Loa Loa (eye worm) glutaminase 2 0.0544 0.0319 0.1594
Schistosoma mansoni tar DNA-binding protein 0.0131 0.0064 0.0145
Echinococcus granulosus g protein coupled receptor 0.0264 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0038 0.0007 0.0032
Mycobacterium tuberculosis Carboxylesterase LipT 0.0051 0.0015 0.0237
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0339 0.0193 0.8418
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0251 0.0139 0.0688
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0072 0.0028 0.0027
Brugia malayi hypothetical protein 0.0301 0.017 0.0843
Loa Loa (eye worm) hypothetical protein 0.0055 0.0018 0.0086
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.002
Toxoplasma gondii histone lysine methyltransferase SET1 0.0247 0.0136 0.2906
Echinococcus granulosus neuropeptide Y receptor 0.0264 0.0147 0.0146
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0001 0.0002
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0396 0.0228 0.0227
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0781 0.0466 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.0044 0.0043
Loa Loa (eye worm) CXXC zinc finger family protein 0.0118 0.0056 0.0279
Echinococcus granulosus ornithine aminotransferase 0.0042 0.001 0.0009
Mycobacterium ulcerans DNA polymerase IV 0.0079 0.0033 0.0605
Echinococcus multilocularis serotonin receptor 0.0264 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.073
Mycobacterium ulcerans L-lysine aminotransferase 0.0042 0.001 0.0118
Trypanosoma cruzi trypanothione reductase, putative 0.0096 0.0043 0.0447
Brugia malayi Nuclear hormone receptor E75 0.0034 0.0005 0.0018
Schistosoma mansoni hypothetical protein 0.0301 0.017 0.0388
Toxoplasma gondii hypothetical protein 0.0269 0.015 0.3199
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0091 0.0484
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0781 0.0466 1
Brugia malayi nuclear receptor RXR 0.0034 0.0005 0.0018
Echinococcus multilocularis acetylcholinesterase 0.0304 0.0171 0.017
Brugia malayi Steroid receptor seven-up type 2 0.0072 0.0028 0.0135
Plasmodium falciparum thioredoxin reductase 0.0033 0.0004 0.0066
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0139 0.0739
Brugia malayi von Willebrand factor type A domain containing protein 0.0301 0.017 0.0844
Brugia malayi AKH receptor 0.0264 0.0147 0.0729
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0264 0.0147 0.0729
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0089 0.0039 0.041
Trypanosoma cruzi PAB1-binding protein , putative 0.0301 0.017 0.1833
Schistosoma mansoni amine GPCR 0.0264 0.0147 0.0335

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) Agonist activity at human GPBAR1 expressed in HEK293T cells assessed as stimulation of cAMP response element-mediated receptor transactivation at 10 uM by luciferase reporter gene assay ChEMBL. 25162837
Activity (binding) Agonist activity at FXR (unknown origin) expressed in human HepG2 cells assessed as stimulation of FXR response element IR1-mediated receptor transactivation at 10 uM by luciferase reporter gene assay ChEMBL. 25162837
Inhibition (binding) Antagonist activity against FXR (unknown origin) expressed in human HepG2 cells assessed as inhibition of CDCA-induced stimulation of FXR response element IR1-mediated receptor transactivation at 50 uM by luciferase reporter gene assay ChEMBL. 25162837

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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