Detailed information for compound 936443

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 362.55 | Formula: C17H20K2N2O2
  • H donors: 4 H acceptors: 2 LogP: 3.1 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-]c1ccccc1CNCCCNCc1ccccc1[O-].[K+].[K+]
  • InChi: 1S/C17H22N2O2.2K/c20-16-8-3-1-6-14(16)12-18-10-5-11-19-13-15-7-2-4-9-17(15)21;;/h1-4,6-9,18-21H,5,10-13H2;;/q;2*+1/p-2
  • InChiKey: OMSRUAYDLZYRTO-UHFFFAOYSA-L  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0786 0.0935 0.1563
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0205 0.0023 0.0023
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.1587 0.219 0.2799
Entamoeba histolytica PH domain containing protein kinase, putative 0.0594 0.0634 0.5486
Brugia malayi Immunoglobulin I-set domain containing protein 0.036 0.0267 0.0341
Loa Loa (eye worm) TK/FER protein kinase 0.0636 0.0699 0.0893
Schistosoma mansoni serine/threonine protein kinase 0.0289 0.0155 0.0396
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0786 0.0935 0.0935
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0334 0.0225 0.0288
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0532 0.0536 0.0974
Schistosoma mansoni tyrosine kinase 0.0322 0.0207 0.0528
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0497 0.0482 0.0616
Schistosoma mansoni serine/threonine protein kinase 0.0306 0.0182 0.0464
Brugia malayi protein unc-22 0.0297 0.0168 0.0215
Entamoeba histolytica protein kinase domain containing protein 0.0455 0.0416 0.3597
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.0108 0.0276
Giardia lamblia Kinase, STE STE20 0.0935 0.1169 1
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.0158 0.1355
Entamoeba histolytica cell division protein kinase 2, putative 0.0377 0.0293 0.2536
Entamoeba histolytica protein kinase, putative 0.0264 0.0116 0.1006
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.1417 0.1924 0.2459
Loa Loa (eye worm) AUR protein kinase 0.0455 0.0416 0.0531
Schistosoma mansoni protein kinase 0.1824 0.2563 0.6554
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.0158 0.1355
Trichomonas vaginalis STE family protein kinase 0.0285 0.0149 0.1274
Brugia malayi Protein kinase domain containing protein 0.0344 0.0241 0.0308
Schistosoma mansoni serine/threonine protein kinase 0.1292 0.1728 0.4419
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.3696 0.5499 0.7028
Brugia malayi Furin-like cysteine rich region family protein 0.0819 0.0986 0.126
Brugia malayi Hr1 repeat family protein 0.1319 0.1771 0.2263
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.2177 0.3116 0.3116
Echinococcus granulosus tyrosine protein kinase Blk 0.0661 0.0738 0.1234
Echinococcus multilocularis expressed conserved protein 0.0223 0.0052 0.0052
Trichomonas vaginalis AGC family protein kinase 0.0455 0.0416 0.3555
Brugia malayi casein kinase I 0.0497 0.0482 0.0616
Brugia malayi P38 map kinase family protein 2 0.3696 0.5499 0.7028
Onchocerca volvulus 0.0532 0.0536 0.0646
Schistosoma mansoni serine/threonine protein kinase 0.1319 0.1771 0.453
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1861 0.2621 0.2621
Brugia malayi casein kinase 1, delta 0.0497 0.0482 0.0616
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1268 0.1691 0.2161
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.1695 0.2361 0.3946
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0859 0.1049 0.134
Echinococcus granulosus rho-associated protein kinase 1 0.0695 0.0791 0.1323
Schistosoma mansoni serine/threonine protein kinase 0.0827 0.0998 0.2554
Leishmania major protein kinase, putative 0.0455 0.0416 0.0756
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1157 0.1516 0.1516
Brugia malayi Protein kinase domain containing protein 0.0252 0.0097 0.0123
Echinococcus granulosus roundabout 2 0.0238 0.0075 0.0126
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0286 0.0151 0.0385
Plasmodium falciparum serine/threonine protein kinase, putative 0.0455 0.0416 0.3597
Trichomonas vaginalis CAMK family protein kinase 0.0263 0.0114 0.0975
Trichomonas vaginalis CMGC family protein kinase 0.0927 0.1156 0.9885
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0455 0.0416 0.3597
Echinococcus multilocularis mitogen activated protein kinase 11 0.3696 0.5499 0.5499
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.0158 0.1355
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1695 0.2361 0.3017
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0935 0.1169 0.2126
Brugia malayi p70 ribosomal S6 kinase beta 0.0551 0.0566 0.0723
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0827 0.0998 0.0998
Echinococcus granulosus serine:threonine protein kinase 0.0243 0.0083 0.0139
Loa Loa (eye worm) hypothetical protein 0.0621 0.0675 0.0863
Loa Loa (eye worm) gastrulation defective protein 1 0.1166 0.153 0.1956
Trichomonas vaginalis STE family protein kinase 0.0935 0.1169 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0211 0.0032 0.0041
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0671 0.0754 0.0964
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0099 0.0254
Plasmodium falciparum calcium-dependent protein kinase 4 0.0407 0.034 0.294
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0263 0.0114 0.0146
Brugia malayi Serine/threonine-protein kinase Pim-3 0.1695 0.2361 0.3017
Onchocerca volvulus Serine\/threonine kinase homolog 0.0263 0.0114 0.0105
Brugia malayi serine/threonine kinase 12 0.0455 0.0416 0.0531
Schistosoma mansoni serine/threonine protein kinase 0.0432 0.0379 0.097
Echinococcus granulosus mitogen activated protein kinase 14 0.3696 0.5499 0.9193
Brugia malayi bone morphogenetic protein type 1 receptor 0.075 0.0878 0.1122
Loa Loa (eye worm) hypothetical protein 0.0442 0.0395 0.0505
Brugia malayi protein kinase C II. 0.0556 0.0574 0.0733
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0786 0.0935 0.0935
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.0158 0.0405
Onchocerca volvulus 0.0743 0.0868 0.1072
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0377 0.0293 0.049
Brugia malayi Protein kinase domain containing protein 0.2712 0.3957 0.5056
Trichomonas vaginalis AGC family protein kinase 0.0455 0.0416 0.3555
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0289 0.0155 0.0259
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0228 0.0059 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.1695 0.2361 0.6038
Echinococcus granulosus protein kinase shaggy 0.0927 0.1156 0.1932
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0859 0.1049 0.1049
Trichomonas vaginalis AGC family protein kinase 0.0455 0.0416 0.3555
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0371 0.0284 0.0475
Brugia malayi putative serine/threonine kinase SADA gamma 0.0291 0.0158 0.0202
Brugia malayi cyclin-dependent kinase 7 homolog 0.0453 0.0413 0.0528
Echinococcus granulosus cGMP dependent protein kinase 1 0.0223 0.0052 0.0087
Plasmodium vivax protein kinase Crk2 0.0377 0.0293 0.2536
Loa Loa (eye worm) TK/FER protein kinase 0.0344 0.0241 0.0308
Schistosoma mansoni tyrosine kinase 0.0819 0.0986 0.2521
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0407 0.034 0.294
Plasmodium falciparum calcium-dependent protein kinase 3 0.0407 0.034 0.294
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.056 0.058 0.1054
Giardia lamblia Kinase, NEK 0.0225 0.0054 0.0465
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1268 0.1691 0.2161
Loa Loa (eye worm) TK/ABL protein kinase 0.1779 0.2493 0.3186
Trypanosoma brucei rac serine-threonine kinase, putative 0.0585 0.062 0.1127
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0407 0.034 0.0568
Brugia malayi Peroxidasin 0.0213 0.0036 0.0046
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0491 0.0471 0.0471
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0238 0.0075 0.0075
Schistosoma mansoni cell adhesion molecule 0.0238 0.0075 0.0192
Echinococcus multilocularis tyrosine protein kinase otk 0.0211 0.0032 0.0032
Echinococcus granulosus casein kinase I delta 0.0497 0.0482 0.0805
Entamoeba histolytica casein kinase, putative 0.0497 0.0482 0.4169
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1157 0.1516 0.1516
Schistosoma mansoni roundabout 0.0211 0.0032 0.0083
Trypanosoma brucei protein kinase, putative 0.0927 0.1156 0.2101
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0291 0.0158 0.0288
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0626 0.0683 0.1142
Loa Loa (eye worm) TK/FER protein kinase 0.0344 0.0241 0.0308
Schistosoma mansoni serine/threonine protein kinase 0.0827 0.0998 0.2554
Echinococcus granulosus dual specificity 0.0228 0.0059 0.0098
Brugia malayi Protein kinase domain containing protein 0.3435 0.5091 0.6506
Giardia lamblia Kinase, CMGC DYRK 0.0228 0.0059 0.0502
Plasmodium vivax serine/threonine kinase-1, putative 0.0838 0.1016 0.879
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0289 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0498 0.0482 0.0616
Echinococcus granulosus tyrosine protein kinase Fyn 0.0786 0.0935 0.1563
Echinococcus multilocularis activated cdc42 kinase 1 0.1332 0.1792 0.1792
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.1417 0.1924 0.2459
Schistosoma mansoni growth factor receptor-bound protein 0.0286 0.0151 0.0385
Loa Loa (eye worm) CAMK protein kinase 0.0297 0.0168 0.0215
Entamoeba histolytica protein kinase, putative 0.0408 0.0342 0.2957
Echinococcus granulosus NDR protein kinase 0.0432 0.0379 0.0634
Schistosoma mansoni serine/threonine kinase 0.0356 0.026 0.0665
Echinococcus multilocularis serine:threonine protein kinase N2 0.0887 0.1093 0.1093
Brugia malayi Immunoglobulin I-set domain containing protein 0.0211 0.0032 0.0041
Echinococcus multilocularis epidermal growth factor receptor 0.0685 0.0776 0.0776
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0827 0.0998 0.1669
Schistosoma mansoni vav2 0.0318 0.02 0.0512
Echinococcus granulosus peroxidasin 0.0213 0.0036 0.006
Trichomonas vaginalis CMGC family protein kinase 0.0228 0.0059 0.0502
Brugia malayi Protein kinase domain containing protein 0.1332 0.1792 0.229
Schistosoma mansoni protein kinase 0.0309 0.0186 0.0476
Plasmodium vivax protein kinase, putative 0.0198 0.0012 0.0102
Brugia malayi Immunoglobulin I-set domain containing protein 0.0211 0.0032 0.0041
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0297 0.0168 0.0215
Giardia lamblia Kinase, NEK 0.0225 0.0054 0.0465
Echinococcus multilocularis c Jun NH2 terminal kinase 0.2175 0.3113 0.3113
Entamoeba histolytica protein kinase, putative 0.0432 0.0379 0.3281
Brugia malayi EGF-like domain containing protein 0.0216 0.0041 0.0052
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.1824 0.2563 0.2563
Trypanosoma cruzi cdc2-related kinase 1 0.0377 0.0293 0.0533
Echinococcus granulosus cyclin dependent kinase 19 0.1292 0.1728 0.2888
Entamoeba histolytica serine/threonine protein kinase, putative 0.0291 0.0158 0.137
Schistosoma mansoni serine/threonine protein kinase 0.0223 0.0052 0.0133
Echinococcus granulosus dual specificity 0.0832 0.1007 0.1684
Echinococcus multilocularis casein kinase i 0.0497 0.0482 0.0482
Schistosoma mansoni titin 0.0211 0.0032 0.0083
Echinococcus multilocularis protein KINase family member (kin 25) 0.0626 0.0683 0.0683
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0838 0.1016 0.1847
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0259 0.0108 0.0138
Schistosoma mansoni hypothetical protein 0.0224 0.0053 0.0136
Brugia malayi hypothetical protein 0.2177 0.3116 0.3983
Loa Loa (eye worm) TK/FER protein kinase 0.0344 0.0241 0.0308
Loa Loa (eye worm) hypothetical protein 0.0453 0.0412 0.0526
Trichomonas vaginalis CMGC family protein kinase 0.0228 0.0059 0.0502
Brugia malayi Immunoglobulin I-set domain containing protein 0.0211 0.0032 0.0041
Echinococcus granulosus twitchin 0.074 0.0863 0.1443
Onchocerca volvulus 0.0778 0.0922 0.1142
Schistosoma mansoni tyrosine kinase 0.1157 0.1516 0.3878
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.056 0.058 0.5018
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0786 0.0935 0.0935
Loa Loa (eye worm) hypothetical protein 0.1332 0.1792 0.229
Schistosoma mansoni serine/threonine-protein kinase 0.0279 0.0139 0.0356
Schistosoma mansoni tyrosine kinase 0.1047 0.1344 0.3438
Echinococcus multilocularis tyrosine protein kinase Blk 0.0661 0.0738 0.0738
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0407 0.034 0.294
Brugia malayi Fibronectin type III domain containing protein 0.0498 0.0482 0.0616
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.056 0.058 0.0969
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0291 0.0158 0.0158
Giardia lamblia Kinase, AGC AKT 0.0789 0.0939 0.8031
Brugia malayi Egg laying defective protein 4 0.0223 0.0052 0.0067
Echinococcus granulosus tyrosine protein kinase ABL1 0.1779 0.2493 0.4167
Entamoeba histolytica protein kinase, putative 0.0407 0.034 0.294
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0315 0.0195 0.1688
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0455 0.0416 0.0695
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0225 0.0054 0.0471
Brugia malayi Variant SH3 domain containing protein 0.0196 0.001 0.0012
Brugia malayi Variant SH3 domain containing protein 0.0283 0.0146 0.0187
Echinococcus granulosus serine:threonine protein kinase 0.0243 0.0083 0.0139
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0211 0.0032 0.0032
Brugia malayi protein C17H12.11 0.0483 0.046 0.0588
Schistosoma mansoni tyrosine kinase 0.1619 0.2241 0.5731
Brugia malayi Immunoglobulin I-set domain containing protein 0.0238 0.0075 0.0096
Brugia malayi hypothetical protein 0.0532 0.0536 0.0685
Schistosoma mansoni serine/threonine protein kinase 0.0832 0.1007 0.2576
Schistosoma mansoni titin 0.0297 0.0168 0.043
Onchocerca volvulus 0.1911 0.27 0.3423
Echinococcus multilocularis 0.0191 0.0001 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.1095 0.1419 0.363
Echinococcus granulosus aurora kinase A 0.0455 0.0416 0.0695
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0838 0.1016 0.1847
Giardia lamblia Kinase, AGC PKA 0.0245 0.0085 0.073
Echinococcus granulosus tyrosine kinase 0.0661 0.0738 0.1234
Echinococcus multilocularis aurora kinase A 0.0455 0.0416 0.0416
Loa Loa (eye worm) hypothetical protein 0.0211 0.0032 0.0041
Onchocerca volvulus 0.0497 0.0482 0.0577
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0377 0.0293 0.0533
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0283 0.0146 0.0374
Schistosoma mansoni serine/threonine protein kinase 0.056 0.058 0.1483
Echinococcus multilocularis c src tyrosine kinase 0.047 0.0438 0.0438
Brugia malayi ephrin receptor 1 precursor 0.0212 0.0035 0.0044
Loa Loa (eye worm) AGC/AKT protein kinase 0.0585 0.062 0.0792
Schistosoma mansoni serine/threonine protein kinase 0.0299 0.0171 0.0437
Giardia lamblia Kinase, NEK 0.0225 0.0054 0.0465
Schistosoma mansoni protein kinase C mu 0.0869 0.1065 0.2724
Plasmodium falciparum cGMP-dependent protein kinase 0.0223 0.0052 0.045
Trichomonas vaginalis STE family protein kinase 0.0285 0.0149 0.1274
Trichomonas vaginalis CK1 family protein kinase 0.0497 0.0482 0.4121
Echinococcus multilocularis cyclin dependent kinase 9 0.0282 0.0145 0.0145
Brugia malayi Immunoglobulin I-set domain containing protein 0.0238 0.0075 0.0096
Schistosoma mansoni protein kinase 0.0455 0.0416 0.1063
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0927 0.1156 1
Echinococcus granulosus serine:threonine kinase SAD 1 0.0291 0.0158 0.0265
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0935 0.1169 0.2126
Echinococcus granulosus tyrosine protein kinase HCK 0.05 0.0486 0.0813
Plasmodium vivax calcium-dependent protein kinase, putative 0.0407 0.034 0.294
Loa Loa (eye worm) hypothetical protein 0.0211 0.0032 0.0041
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0671 0.0754 0.0964
Brugia malayi Protein kinase domain containing protein 0.0671 0.0754 0.0964
Echinococcus granulosus serine:threonine protein kinase N2 0.0887 0.1093 0.1828
Brugia malayi Variant SH3 domain containing protein 0.0286 0.0151 0.0193
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.047 0.0439 0.1124
Echinococcus granulosus tyrosine protein kinase shark 0.0549 0.0563 0.0942
Trichomonas vaginalis CAMK family protein kinase 0.0263 0.0114 0.0975
Loa Loa (eye worm) hypothetical protein 0.0251 0.0096 0.0122
Entamoeba histolytica PH domain containing protein kinase, putative 0.0279 0.0139 0.1206
Brugia malayi map kinase activated protein kinase protein 2 0.0473 0.0444 0.0567
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0283 0.0146 0.0374
Leishmania major protein kinase, putative 0.0838 0.1016 0.1847
Onchocerca volvulus 0.0344 0.0241 0.0268
Brugia malayi RhoGAP domain containing protein 0.0283 0.0146 0.0187
Onchocerca volvulus 0.0251 0.0096 0.0081
Echinococcus granulosus activated cdc42 kinase 1 0.1332 0.1792 0.2995
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0407 0.034 0.034
Trypanosoma brucei cdc2-related kinase 1 0.0377 0.0293 0.0533
Echinococcus granulosus serine:threonine protein kinase N2 0.1319 0.1771 0.2961
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.0284 0.0726
Schistosoma mansoni kinase 0.0259 0.0108 0.0276
Trichomonas vaginalis CMGC family protein kinase 0.0377 0.0293 0.2507
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0537 0.0544 0.0909
Schistosoma mansoni serine/threonine protein kinase 0.1329 0.1787 0.4569
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0432 0.0379 0.0634
Loa Loa (eye worm) hypothetical protein 0.0444 0.0398 0.0508
Echinococcus multilocularis tyrosine protein kinase ABL1 0.1779 0.2493 0.2493
Trypanosoma cruzi casein kinase, putative 0.0497 0.0482 0.0876
Loa Loa (eye worm) hypothetical protein 0.0544 0.0555 0.0709
Echinococcus multilocularis serine:threonine protein kinase 0.0243 0.0083 0.0083
Echinococcus granulosus neuroglian 0.0615 0.0666 0.1113
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0238 0.0075 0.0096
Entamoeba histolytica hypothetical protein 0.0832 0.1007 0.8716
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0243 0.0083 0.0106
Loa Loa (eye worm) TK protein kinase 0.0475 0.0447 0.0571
Loa Loa (eye worm) TK protein kinase 0.05 0.0486 0.0621
Echinococcus multilocularis roundabout 2 0.0238 0.0075 0.0075
Plasmodium vivax glycogen synthase kinase 3, putative 0.0927 0.1156 1
Echinococcus multilocularis dual specificity protein kinase clk2 0.0838 0.1016 0.1016
Echinococcus multilocularis lachesin 0.0211 0.0032 0.0032
Echinococcus granulosus cyclin dependent kinase 5 0.0377 0.0293 0.049
Trypanosoma cruzi casein kinase, putative 0.0497 0.0482 0.0876
Echinococcus multilocularis Immunoglobulin 0.047 0.0439 0.0439
Loa Loa (eye worm) AGC/PKG protein kinase 0.0223 0.0052 0.0067
Loa Loa (eye worm) hypothetical protein 0.0498 0.0482 0.0616
Echinococcus multilocularis tyrosine protein kinase shark 0.0549 0.0563 0.0563
Echinococcus multilocularis cyclin dependent kinase 7 0.043 0.0376 0.0376
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.0158 0.1355
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0838 0.1016 0.1847
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.056 0.058 0.1054
Echinococcus multilocularis mitogen activated protein kinase 14 0.3696 0.5499 0.5499
Echinococcus multilocularis transfer RNA-Thr 0.1332 0.1792 0.1792
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.0158 0.1355
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1095 0.1419 0.1814
Echinococcus granulosus cyclin dependent kinase 9 0.0282 0.0145 0.0242
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.0158 0.1355
Trichomonas vaginalis CMGC family protein kinase 0.0228 0.0059 0.0502
Echinococcus granulosus cGMP dependent protein kinase 0.0223 0.0052 0.0087
Schistosoma mansoni cell adhesion molecule 0.0211 0.0032 0.0083
Loa Loa (eye worm) hypothetical protein 0.0666 0.0747 0.0955
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.0158 0.1355
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1075 0.1387 0.1387
Loa Loa (eye worm) hypothetical protein 0.0286 0.0151 0.0193
Echinococcus multilocularis hemicentin 1 0.0211 0.0032 0.0032
Brugia malayi hypothetical protein 0.0224 0.0053 0.0068
Brugia malayi Protein kinase domain containing protein 0.0344 0.0241 0.0308
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.0158 0.1355
Loa Loa (eye worm) hypothetical protein 0.0224 0.0053 0.0068
Schistosoma mansoni serine/threonine protein kinase 0.0838 0.1016 0.2598
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.047 0.0438 0.1121
Schistosoma mansoni protein kinase 0.0285 0.0149 0.0381
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0238 0.0075 0.0075
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0228 0.0059 0.0107
Brugia malayi Immunoglobulin I-set domain containing protein 0.0297 0.0168 0.0215
Onchocerca volvulus 0.0344 0.0241 0.0268
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0551 0.0566 0.0723
Trypanosoma brucei cdc2-related kinase 3 0.0377 0.0293 0.0533
Entamoeba histolytica protein kinase domain containing protein 0.0927 0.1156 1
Loa Loa (eye worm) AGC/PKN protein kinase 0.1319 0.1771 0.2263
Trichomonas vaginalis CAMK family protein kinase 0.0263 0.0114 0.0975
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0432 0.0379 0.0379
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0291 0.0158 0.0288
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0832 0.1007 0.1287
Echinococcus granulosus contactin 0.0238 0.0075 0.0126
Brugia malayi Protein kinase domain containing protein 0.0525 0.0526 0.0672
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.056 0.058 0.058
Echinococcus granulosus Vam6:Vps39 protein 0.0532 0.0536 0.0895
Echinococcus granulosus tyrosine protein kinase otk 0.0211 0.0032 0.0054
Entamoeba histolytica protein kinase, putative 0.0299 0.017 0.1474
Echinococcus granulosus protein tyrosine kinase 0.2683 0.391 0.6536
Trichomonas vaginalis CAMK family protein kinase 0.0407 0.034 0.2907
Echinococcus granulosus lachesin 0.0211 0.0032 0.0054
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0196 0.0009 0.0011
Schistosoma mansoni protein kinase 0.1824 0.2563 0.6554
Giardia lamblia Kinase, AGC PKA 0.056 0.058 0.4961
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0636 0.0699 0.0699
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0532 0.0536 0.0974
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0532 0.0536 0.137
Loa Loa (eye worm) hypothetical protein 0.0707 0.081 0.1035
Toxoplasma gondii AGC kinase 0.056 0.058 0.5018
Entamoeba histolytica protein kinase domain containing protein 0.0927 0.1156 1
Brugia malayi Protein kinase domain containing protein 0.0333 0.0223 0.0285
Schistosoma mansoni protein kinase 0.0497 0.0482 0.1232
Trichomonas vaginalis CAMK family protein kinase 0.0263 0.0114 0.0975
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.4003 0.5982 1
Brugia malayi Protein kinase domain containing protein 0.0344 0.0241 0.0308
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.056 0.058 0.0969
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.0158 0.1355
Loa Loa (eye worm) AUR protein kinase 0.0455 0.0416 0.0531
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.0158 0.1355
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0371 0.0284 0.0284
Trichomonas vaginalis AGC family protein kinase 0.0585 0.062 0.5303
Plasmodium falciparum NIMA related kinase 1 0.0225 0.0054 0.0471
Schistosoma mansoni hypothetical protein 0.0532 0.0536 0.137
Echinococcus granulosus fibroblast growth factor receptor 4 0.1157 0.1516 0.2535
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0455 0.0416 0.0416
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0603 0.0647 0.0827
Schistosoma mansoni protein kinase 0.0716 0.0824 0.2109
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.0158 0.1355
Loa Loa (eye worm) AUR protein kinase 0.0455 0.0416 0.0531
Schistosoma mansoni tyrosine kinase 0.0549 0.0563 0.1441
Loa Loa (eye worm) TK/EPH protein kinase 0.0262 0.0112 0.0143
Loa Loa (eye worm) hypothetical protein 0.0224 0.0053 0.0068
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0196 0.001 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.024 0.0078 0.0199
Loa Loa (eye worm) hypothetical protein 0.0453 0.0412 0.0526
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0832 0.1007 0.1831
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0228 0.0059 0.0075
Onchocerca volvulus 0.0372 0.0285 0.0324
Trichomonas vaginalis CAMK family protein kinase 0.0243 0.0083 0.0712
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0125 0.032
Toxoplasma gondii aurora kinase 0.0455 0.0416 0.3597
Echinococcus granulosus hemicentin 1 0.0211 0.0032 0.0054
Brugia malayi Protein kinase domain containing protein 0.0832 0.1007 0.1287
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.1448 0.1973 0.3298
Brugia malayi STE20-like kinase MST 0.0341 0.0237 0.0302
Echinococcus multilocularis tyrosine protein kinase HCK 0.05 0.0486 0.0486
Schistosoma mansoni tyrosine kinase 0.0502 0.0489 0.125
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.1154 0.1512 0.1932
Trichomonas vaginalis AGC family protein kinase 0.0196 0.0009 0.0073
Schistosoma mansoni protein kinase 0.0285 0.0149 0.0381
Entamoeba histolytica protein kinase, putative 0.0551 0.0566 0.4897
Schistosoma mansoni tyrosine kinase 0.0626 0.0683 0.1747
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0594 0.0633 0.0633
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1896 0.2676 0.3419
Trichomonas vaginalis STE family protein kinase 0.0935 0.1169 1
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0344 0.0241 0.2087
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0432 0.0379 0.0379
Echinococcus multilocularis PAK box P21 Rho binding 0.0264 0.0116 0.0116
Echinococcus multilocularis protein kinase c iota type 0.0634 0.0697 0.0697
Schistosoma mansoni serine/threonine protein kinase 0.0473 0.0444 0.1135
Loa Loa (eye worm) hypothetical protein 0.0681 0.077 0.0984
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0832 0.1007 0.1831
Echinococcus multilocularis calcium activated potassium channel 0.0254 0.0099 0.0099
Entamoeba histolytica protein kinase domain containing protein 0.0832 0.1007 0.8716
Echinococcus granulosus NCK adaptor protein 0.0286 0.0151 0.0252
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0935 0.1169 0.2126
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0263 0.0114 0.019
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0279 0.014 0.0179
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0228 0.0059 0.0107
Onchocerca volvulus Slit protein homolog 0.0216 0.0041 0.0011
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0927 0.1156 0.1477
Schistosoma mansoni protein kinase 0.0279 0.014 0.0358
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0223 0.0052 0.0052
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0532 0.0536 0.0974
Entamoeba histolytica protein kinase 2, putative 0.0245 0.0085 0.0738
Entamoeba histolytica protein kinase domain containing protein 0.0309 0.0186 0.1612
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0211 0.0032 0.0041
Entamoeba histolytica protein kinase, putative 0.0832 0.1007 0.8716
Brugia malayi hypothetical protein 0.0483 0.046 0.0588
Brugia malayi Immunoglobulin I-set domain containing protein 0.0238 0.0075 0.0096
Echinococcus granulosus growth factor receptor bound protein 2 0.0299 0.0171 0.0286
Echinococcus multilocularis insulin receptor 0.1047 0.1344 0.1344
Brugia malayi Immunoglobulin I-set domain containing protein 0.2631 0.383 0.4894
Schistosoma mansoni serine/threonine protein kinase 0.2177 0.3116 0.797
Brugia malayi Doublecortin family protein 0.0239 0.0077 0.0098
Loa Loa (eye worm) hypothetical protein 0.0544 0.0555 0.0709
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0196 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0532 0.0536 0.0685
Schistosoma mansoni septate junction protein 0.0211 0.0032 0.0083
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0059 0.015
Schistosoma mansoni serine/threonine protein kinase 0.024 0.0078 0.0199
Loa Loa (eye worm) TK/FER protein kinase 0.0344 0.0241 0.0308
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0786 0.0935 0.0935
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0245 0.0085 0.0738
Echinococcus multilocularis slit 2 protein 0.0216 0.0041 0.0041
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0497 0.0482 0.0876
Brugia malayi Protein kinase domain containing protein 0.1292 0.1728 0.2208
Brugia malayi Serine/threonine-protein kinase SULU 0.2177 0.3116 0.3983
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0285 0.0149 0.0249
Trypanosoma brucei protein kinase, putative 0.0309 0.0186 0.0339
Schistosoma mansoni tyrosine kinase 0.1542 0.212 0.5422
Plasmodium falciparum serine/threonine protein kinase KIN 0.0291 0.0158 0.137
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0099 0.0254
Schistosoma mansoni cell adhesion molecule 0.0238 0.0075 0.0192
Brugia malayi SH2 domain containing protein 0.0636 0.0699 0.0893
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0286 0.0151 0.0193
Brugia malayi Protein kinase domain containing protein 0.1695 0.2361 0.3017
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0099 0.0254
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0371 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0532 0.0536 0.0685
Schistosoma mansoni serine/threonine-protein kinase 0.0279 0.0139 0.0356
Trichomonas vaginalis CK1 family protein kinase 0.0497 0.0482 0.4121
Toxoplasma gondii histone kinase SNF1, putative 0.0291 0.0158 0.137
Leishmania major protein kinase, putative 0.0309 0.0186 0.0339
Giardia lamblia Kinase, CMGC CDK 0.0377 0.0293 0.2507
Brugia malayi Prion-like- 0.0211 0.0032 0.0041
Brugia malayi Protein kinase domain containing protein 0.1047 0.1344 0.1718
Brugia malayi SRC-1 0.0786 0.0935 0.1195
Entamoeba histolytica hypothetical protein 0.0366 0.0275 0.2381
Echinococcus multilocularis rac serine:threonine kinase 0.0279 0.0139 0.0139
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.1824 0.2563 0.4284
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0838 0.1016 0.1298
Leishmania major protein kinase A catalytic subunit isoform 2 0.056 0.058 0.1054
Echinococcus multilocularis protein kinase c epsilon type 0.0556 0.0574 0.0574
Echinococcus granulosus tyrosine protein kinase Srms 0.0736 0.0857 0.1432
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0205 0.0023 0.0038
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0455 0.0416 0.3597
Loa Loa (eye worm) hypothetical protein 0.056 0.058 0.0741
Trichomonas vaginalis CAMK family protein kinase 0.0205 0.0023 0.0193
Echinococcus granulosus tyrosine protein kinase Src42A 0.0491 0.0471 0.0787
Entamoeba histolytica protein kinase, putative 0.0228 0.0059 0.0508
Echinococcus multilocularis cyclin dependent kinase 0.0377 0.0293 0.0293
Schistosoma mansoni tyrosine kinase 0.047 0.0438 0.1121
Brugia malayi Immunoglobulin I-set domain containing protein 0.0211 0.0032 0.0041
Echinococcus granulosus hypothetical protein 0.0712 0.0819 0.1368
Trichomonas vaginalis STE family protein kinase 0.0935 0.1169 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0498 0.0482 0.0616
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.0114 0.0291
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0609 0.0657 0.084
Trypanosoma cruzi polo-like protein kinase, putative 0.0263 0.0114 0.0207
Giardia lamblia Kinase, CAMK CAMKL 0.0315 0.0195 0.1668
Echinococcus granulosus raf serine:threonine protein kinase 0.0306 0.0182 0.0303
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0432 0.0379 0.0634
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.3696 0.5499 1
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0407 0.034 0.294
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0685 0.0776 0.1297
Echinococcus granulosus c-Jun N-terminal kinases 0.2175 0.3113 0.5204
Loa Loa (eye worm) hypothetical protein 0.0344 0.0241 0.0308
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0838 0.1016 0.1847
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1095 0.1419 0.1419
Echinococcus multilocularis activin receptor type 0.3204 0.4728 0.4728
Trichomonas vaginalis CK1 family protein kinase 0.0497 0.0482 0.4121
Brugia malayi Protein kinase domain containing protein 0.0608 0.0656 0.0838
Brugia malayi Variant SH3 domain containing protein 0.0286 0.0151 0.0193
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0252 0.0097 0.0123
Echinococcus multilocularis mitogen activated protein kinase 11 0.3696 0.5499 0.5499
Echinococcus granulosus epidermal growth factor receptor 0.0819 0.0986 0.1648
Echinococcus granulosus insulin receptor 0.1047 0.1344 0.2247
Echinococcus multilocularis dual specificity 0.0228 0.0059 0.0059
Schistosoma mansoni tyrosine kinase 0.2683 0.391 1
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0333 0.0223 0.0285
Echinococcus granulosus casein kinase I alpha 0.0497 0.0482 0.0805
Echinococcus multilocularis dual specificity 0.0832 0.1007 0.1007
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.0284 0.0726
Echinococcus granulosus neuroglian 0.0238 0.0075 0.0126
Schistosoma mansoni adapter molecule crk 0.0286 0.0151 0.0385
Plasmodium vivax casein kinase 1, putative 0.0497 0.0482 0.4169
Echinococcus multilocularis 0.0716 0.0824 0.0824
Trichomonas vaginalis CAMK family protein kinase 0.0286 0.0151 0.1289
Echinococcus granulosus beta-adrenergic receptor kinase 0.024 0.0078 0.013
Echinococcus multilocularis serine:threonine protein kinase N2 0.1319 0.1771 0.1771
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0927 0.1156 0.1477
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0286 0.0151 0.1305
Trypanosoma cruzi casein kinase, putative 0.0497 0.0482 0.0876
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0869 0.1065 0.1361
Loa Loa (eye worm) hypothetical protein 0.0442 0.0395 0.0505
Plasmodium falciparum calcium-dependent protein kinase 5 0.0407 0.034 0.294
Schistosoma mansoni serine/threonine protein kinase 0.2175 0.3113 0.7962
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0693 0.0788 0.0788
Loa Loa (eye worm) hypothetical protein 0.0291 0.0158 0.0202
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0473 0.0444 0.0742
Onchocerca volvulus 0.0621 0.0675 0.0825
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1695 0.2361 0.3017
Echinococcus multilocularis casein kinase I alpha 0.0497 0.0482 0.0482
Brugia malayi Protein kinase domain containing protein 0.0838 0.1016 0.1298
Brugia malayi Immunoglobulin I-set domain containing protein 0.1301 0.1743 0.2227
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0341 0.0237 0.0302
Trypanosoma cruzi polo-like protein kinase, putative 0.0263 0.0114 0.0207
Schistosoma mansoni serine/threonine protein kinase 0.0594 0.0633 0.162
Brugia malayi Protein kinase domain containing protein 0.0609 0.0657 0.084
Brugia malayi serine/threonine protein kinase 6 0.0455 0.0416 0.0531
Brugia malayi Protein kinase domain containing protein 0.0344 0.0241 0.0308
Entamoeba histolytica protein kinase domain containing protein 0.0228 0.0059 0.0508
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0786 0.0935 0.0935
Trichomonas vaginalis CAMK family protein kinase 0.0263 0.0114 0.0975
Schistosoma mansoni septate junction protein 0.0211 0.0032 0.0083
Echinococcus granulosus protein kinase c epsilon type 0.0556 0.0574 0.0959
Echinococcus multilocularis G protein coupled receptor kinase 6 0.1154 0.1512 0.1512
Plasmodium falciparum protein serine/threonine kinase-1 0.0838 0.1016 0.879
Entamoeba histolytica serine/threonine protein kinase, putative 0.0263 0.0114 0.0986
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1154 0.1512 0.1932
Onchocerca volvulus 0.0224 0.0053 0.0027
Brugia malayi Protein kinase domain containing protein 0.0671 0.0754 0.0964
Echinococcus multilocularis ephrin type A receptor 4 A 0.0245 0.0086 0.0086
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.056 0.058 0.058
Trichomonas vaginalis AGC family protein kinase 0.0455 0.0416 0.3555
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0657 0.0733 0.0733
Toxoplasma gondii casein kinase I 0.0497 0.0482 0.4169
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0823 0.0993 0.1805
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0838 0.1016 0.1847
Echinococcus multilocularis 0.0712 0.0819 0.0819
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.0158 0.1355
Brugia malayi serine/threonine-protein kinase plk-2 0.0263 0.0114 0.0146
Brugia malayi C1-like domain containing protein 0.0869 0.1065 0.1361
Echinococcus multilocularis neuroglian 0.0238 0.0075 0.0075
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0238 0.0075 0.0075
Trichomonas vaginalis AGC family protein kinase 0.0432 0.0379 0.3244
Loa Loa (eye worm) hypothetical protein 0.3027 0.445 0.5687
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0661 0.0738 0.1234
Echinococcus multilocularis roundabout 2 0.0238 0.0075 0.0075
Echinococcus multilocularis casein kinase I alpha 0.0497 0.0482 0.0482
Brugia malayi Stress-activated protein kinase jnk-1 0.2175 0.3113 0.3979
Schistosoma mansoni ste20-related kinase 0.0291 0.0159 0.0405
Trichomonas vaginalis AGC family protein kinase 0.0455 0.0416 0.3557
Schistosoma mansoni tyrosine kinase 0.0685 0.0776 0.1985
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0407 0.034 0.294
Echinococcus granulosus dual specificity 0.0228 0.0059 0.0098
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.056 0.058 0.1054
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0786 0.0935 0.0935
Trypanosoma cruzi Protein kinase B 0.0279 0.0139 0.0253
Echinococcus multilocularis serine threonine protein kinase 0.0471 0.0441 0.0441
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0245 0.0085 0.0085
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0289 0.0155 0.0198
Echinococcus granulosus defective proboscis extension response 0.047 0.0439 0.0734
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0328 0.0216 0.0216
Trichomonas vaginalis CMGC family protein kinase 0.0228 0.0059 0.0502
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0309 0.0186 0.0186
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1095 0.1419 0.2373
Loa Loa (eye worm) TK protein kinase 0.0661 0.0738 0.0943
Echinococcus granulosus protein kinase 0.0716 0.0824 0.1378
Giardia lamblia Kinase, CMGC GSK 0.0927 0.1156 0.9885
Echinococcus multilocularis serine:threonine protein kinase N2 0.0432 0.0379 0.0379
Echinococcus multilocularis Immunoglobulin 0.047 0.0439 0.0439
Schistosoma mansoni tyrosine kinase 0.0394 0.032 0.0818
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0291 0.0158 0.0288
Schistosoma mansoni nephrin 0.0238 0.0075 0.0192
Brugia malayi SH2 domain containing protein 0.0344 0.0241 0.0308
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.0158 0.1355
Schistosoma mansoni serine/threonine protein kinase 0.0432 0.0379 0.097
Loa Loa (eye worm) hypothetical protein 0.0532 0.0536 0.0685
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.3696 0.5499 1
Echinococcus granulosus roundabout 2 0.0238 0.0075 0.0126
Echinococcus multilocularis protein kinase shaggy 0.0927 0.1156 0.1156
Schistosoma mansoni serine/threonine protein kinase 0.0377 0.0293 0.0749
Loa Loa (eye worm) hypothetical protein 0.0224 0.0053 0.0068
Loa Loa (eye worm) hypothetical protein 0.0626 0.0683 0.0873
Trichomonas vaginalis AGC family protein kinase 0.0585 0.062 0.5303
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0377 0.0293 0.0374
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.056 0.058 0.5018
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0786 0.0935 0.0935
Echinococcus multilocularis NCK adaptor protein 0.0299 0.0171 0.0171
Echinococcus granulosus tyrosine protein kinase Src64B 0.0786 0.0935 0.1563
Leishmania major protein kinase, putative 0.0838 0.1016 0.1847
Schistosoma mansoni serine/threonine protein kinase 0.0838 0.1016 0.2598
Trichomonas vaginalis AGC family protein kinase 0.0585 0.062 0.5303
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0869 0.1065 0.1361
Trichomonas vaginalis CMGC family protein kinase 0.0377 0.0293 0.2507
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0245 0.0085 0.0143
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0357 0.0261 0.0437
Trichomonas vaginalis AGC family protein kinase 0.0585 0.062 0.5303
Schistosoma mansoni atypical protein kinase C 0.064 0.0706 0.1806
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1075 0.1387 0.2319
Entamoeba histolytica PH domain containing protein kinase, putative 0.0279 0.0139 0.1206
Toxoplasma gondii AGC kinase 0.0551 0.0566 0.4897
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.1695 0.2361 0.2361
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0927 0.1156 0.2101
Loa Loa (eye worm) TK/FER protein kinase 0.0344 0.0241 0.0308
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0283 0.0146 0.0146
Echinococcus granulosus dual specificity mitogen activated protein 0.0935 0.1169 0.1954
Giardia lamblia Kinase, STE STE20 0.0285 0.0149 0.1274
Loa Loa (eye worm) SRC-1 0.0786 0.0935 0.1195
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.3696 0.5499 1
Onchocerca volvulus Tyrosine kinase homolog 0.2239 0.3214 0.4083
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0364 0.0272 0.0348
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0927 0.1156 0.1932
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.043 0.0376 0.0481
Schistosoma mansoni tyrosine kinase 0.0502 0.0489 0.125
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.0158 0.0405
Echinococcus multilocularis cyclin dependent kinase 1 0.0377 0.0293 0.0293
Plasmodium falciparum casein kinase 1 0.0497 0.0482 0.4169
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0407 0.034 0.0618
Entamoeba histolytica protein kinase, putative 0.0585 0.062 0.5365
Echinococcus granulosus cyclin dependent kinase 0.0377 0.0293 0.049
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.3696 0.5499 1
Schistosoma mansoni serine/threonine protein kinase 0.056 0.058 0.1483
Echinococcus multilocularis tyrosine protein kinase Srms 0.0661 0.0738 0.0738
Giardia lamblia Kinase, CMGC CDK 0.0377 0.0293 0.2507
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0357 0.0262 0.0262
Echinococcus granulosus Protein kinase C brain isozyme 0.0594 0.0633 0.1059
Onchocerca volvulus 0.0544 0.0555 0.067
Echinococcus granulosus activated cdc42 kinase 1 0.1332 0.1792 0.2995
Brugia malayi serine/threonine-protein kinase 6 0.0455 0.0416 0.0531
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.056 0.058 0.058
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0786 0.0935 0.0935
Loa Loa (eye worm) hypothetical protein 0.0712 0.0819 0.1046
Echinococcus granulosus tyrosine protein kinase Btk29A 0.1654 0.2297 0.3839
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0285 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0211 0.0032 0.0041
Trichomonas vaginalis CMGC family protein kinase 0.0377 0.0293 0.2507
Loa Loa (eye worm) hypothetical protein 0.0213 0.0036 0.0046
Schistosoma mansoni rap gtpase-activating protein 0.0532 0.0536 0.137
Echinococcus granulosus casein kinase I gamma 0.0299 0.0171 0.0285
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.075 0.0878 0.1122
Plasmodium falciparum protein kinase, putative 0.0309 0.0186 0.1612
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0252 0.0097 0.0097
Echinococcus multilocularis dual specificity 0.0228 0.0059 0.0059
Schistosoma mansoni protein kinase 0.1824 0.2563 0.6554
Entamoeba histolytica protein kinase, putative 0.0299 0.017 0.1474
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0497 0.0482 0.0616
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0556 0.0574 0.0733
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.1695 0.2361 0.2988
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1157 0.1516 0.2535
Onchocerca volvulus 0.0297 0.0168 0.0174
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0328 0.0216 0.036
Schistosoma mansoni protein kinase 0.1248 0.1659 0.4242
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0372 0.0285 0.0518
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.1448 0.1973 0.1973
Brugia malayi Protein kinase domain containing protein 0.1861 0.2621 0.3349
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0263 0.0114 0.0114
Echinococcus granulosus dual specificity protein kinase clk2 0.0838 0.1016 0.1698
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.2175 0.3113 0.3979
Loa Loa (eye worm) hypothetical protein 0.0707 0.081 0.1035
Trichomonas vaginalis STE family protein kinase 0.0285 0.0149 0.1274
Trichomonas vaginalis CAMK family protein kinase 0.0205 0.0023 0.0193
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0306 0.0182 0.1557
Toxoplasma gondii AGC kinase 0.056 0.058 0.5018
Loa Loa (eye worm) AGC/NDR protein kinase 0.0432 0.0379 0.0485
Echinococcus multilocularis epidermal growth factor receptor 0.0819 0.0986 0.0986
Echinococcus granulosus TGF beta receptor type 1 0.0693 0.0788 0.1317
Schistosoma mansoni serine/threonine protein kinase 0.043 0.0376 0.0962
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0291 0.0158 0.0202
Echinococcus granulosus epidermal growth factor receptor 0.0685 0.0776 0.1297
Schistosoma mansoni hypothetical protein 0.0224 0.0053 0.0136
Schistosoma mansoni serine/threonine protein kinase 0.0223 0.0052 0.0133
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.056 0.058 0.1054
Entamoeba histolytica protein kinase, putative 0.0455 0.0416 0.3597
Brugia malayi serine/threonine-protein kinase PAK 7 0.1587 0.219 0.2799
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0636 0.0699 0.1169
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0238 0.0075 0.0192
Loa Loa (eye worm) hypothetical protein 0.0473 0.0443 0.0566
Loa Loa (eye worm) TK/INSR protein kinase 0.1047 0.1344 0.1718
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0285 0.0149 0.0249
Echinococcus multilocularis N chimaerin 0.0283 0.0146 0.0146
Brugia malayi Temporarily assigned gene name protein 59 0.0532 0.0536 0.0685
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0407 0.034 0.0434
Schistosoma mansoni tyrosine kinase 0.047 0.0438 0.1121
Echinococcus granulosus serine:threonine protein kinase TAO1 0.2177 0.3116 0.5209
Echinococcus multilocularis mitogen activated protein kinase 14 0.3696 0.5499 0.5499
Entamoeba histolytica protein kinase, putative 0.0455 0.0416 0.3597
Echinococcus granulosus casein kinase I alpha 0.0497 0.0482 0.0805
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.1154 0.1512 0.2527
Brugia malayi Protein kinase domain containing protein 0.0377 0.0293 0.0374
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0238 0.0075 0.0126
Echinococcus granulosus slit 2 protein 0.0216 0.0041 0.0068
Echinococcus multilocularis twitchin 0.027 0.0125 0.0125
Echinococcus multilocularis rho associated protein kinase 0.0695 0.0791 0.0791
Echinococcus granulosus cGMP dependent protein kinase 1 0.0223 0.0052 0.0087
Schistosoma mansoni protein kinase 0.0309 0.0186 0.0476
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.056 0.058 0.058
Entamoeba histolytica protein kinase, putative 0.05 0.0486 0.4207
Echinococcus granulosus serine:threonine protein kinase 3 0.0341 0.0237 0.0395
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0789 0.0939 0.12
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0309 0.0186 0.0339
Schistosoma mansoni protein kinase 0.0935 0.1169 0.299
Brugia malayi Tyrosine-protein kinase abl-1 0.1018 0.1299 0.166
Brugia malayi Immunoglobulin I-set domain containing protein 0.0211 0.0032 0.0041
Onchocerca volvulus 0.0214 0.0037 0.0006
Echinococcus granulosus MAM 0.0224 0.0053 0.0089
Echinococcus granulosus tyrosine protein kinase Src42A 0.0786 0.0935 0.1563
Schistosoma mansoni tyrosine kinase 0.0786 0.0935 0.2392
Onchocerca volvulus 0.0344 0.0241 0.0268
Schistosoma mansoni serine/threonine protein kinase 0.0407 0.034 0.0869
Echinococcus granulosus TGF-beta receptor type-1 0.0693 0.0788 0.1317
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0239 0.0077 0.0098
Echinococcus multilocularis cyclin dependent kinase 19 0.1292 0.1728 0.1728
Onchocerca volvulus 0.0927 0.1156 0.1441
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.057 0.0595 0.0595
Entamoeba histolytica protein kinase domain containing protein 0.0259 0.0108 0.0934
Echinococcus multilocularis dual specificity mitogen activated protein 0.0935 0.1169 0.1169
Echinococcus multilocularis titin 0.0297 0.0168 0.0168
Echinococcus granulosus roundabout 2 0.0709 0.0813 0.1359
Loa Loa (eye worm) TK/FER protein kinase 0.0344 0.0241 0.0308
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0532 0.0536 0.137
Loa Loa (eye worm) hypothetical protein 0.047 0.0439 0.0561
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0245 0.0085 0.0155
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0746 0.0873 0.1115
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0927 0.1156 0.2955
Echinococcus granulosus cyclin dependent kinase 7 0.043 0.0376 0.0629
Loa Loa (eye worm) hypothetical protein 0.0778 0.0922 0.1178
Brugia malayi hypothetical protein 0.0344 0.0241 0.0308
Onchocerca volvulus 0.0344 0.0241 0.0268
Trypanosoma brucei casein kinase I, isoform 2 0.0497 0.0482 0.0876
Brugia malayi Protein kinase domain containing protein 0.0243 0.0083 0.0106
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0859 0.1049 0.1753
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0097 0.0247
Giardia lamblia Kinase, CAMK CAMKL 0.0315 0.0195 0.1668
Schistosoma mansoni tyrosine kinase 0.0786 0.0935 0.2392
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.024 0.0078 0.01
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0377 0.0293 0.2536
Echinococcus multilocularis hemicentin 1 0.0211 0.0032 0.0032
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0238 0.0075 0.0075
Brugia malayi Protein kinase domain containing protein 0.5178 0.7825 1
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0455 0.0416 0.3597
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0661 0.0738 0.0738
Plasmodium falciparum protein kinase 5 0.0377 0.0293 0.2536
Trichomonas vaginalis AGC family protein kinase 0.0585 0.062 0.5303
Loa Loa (eye worm) IKK protein kinase 0.5178 0.7825 1
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0279 0.0139 0.0253
Echinococcus granulosus dual specificity 0.0228 0.0059 0.0098
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0285 0.0149 0.0149
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0228 0.0059 0.0508
Echinococcus granulosus tyrosine protein kinase Fyn 0.0786 0.0935 0.1563
Loa Loa (eye worm) TK/KIN16 protein kinase 0.2631 0.383 0.4894
Trypanosoma brucei polo-like protein kinase 0.0263 0.0114 0.0207
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0228 0.0059 0.0107
Echinococcus granulosus c src tyrosine kinase 0.047 0.0438 0.0733
Onchocerca volvulus 0.0569 0.0594 0.0721
Brugia malayi cell division control protein 2 homolog 0.0377 0.0293 0.0374
Loa Loa (eye worm) hypothetical protein 0.0216 0.0041 0.0052
Brugia malayi Protein kinase domain containing protein 0.0279 0.014 0.0179
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0309 0.0186 0.0339
Onchocerca volvulus 0.0344 0.0241 0.0268
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0455 0.0416 0.3597
Loa Loa (eye worm) hypothetical protein 0.0976 0.1232 0.1575
Brugia malayi intracellular kinase 0.0927 0.1156 0.1477
Plasmodium falciparum calcium-dependent protein kinase 2 0.0407 0.034 0.294
Echinococcus granulosus activin receptor type 0.3204 0.4728 0.7903
Loa Loa (eye worm) TK/ROR protein kinase 0.0328 0.0216 0.0275
Brugia malayi Protein kinase domain containing protein 0.0344 0.0241 0.0308
Loa Loa (eye worm) protein kinase domain-containing protein 0.0299 0.0171 0.0218
Echinococcus multilocularis casein kinase I delta 0.0497 0.0482 0.0482
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0609 0.0657 0.084
Loa Loa (eye worm) hypothetical protein 0.0483 0.046 0.0588
Schistosoma mansoni protein kinase 0.0264 0.0116 0.0297
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0935 0.1169 0.1494
Schistosoma mansoni growth factor receptor-bound protein 0.0299 0.0171 0.0437
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.0158 0.0405
Echinococcus multilocularis casein kinase I delta 0.0497 0.0482 0.0482
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0935 0.1169 0.1494
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0786 0.0935 0.1563
Entamoeba histolytica protein kinase, putative 0.0927 0.1156 1
Schistosoma mansoni serine/threonine protein kinase 0.0859 0.1049 0.2683
Schistosoma mansoni serine/threonine protein kinase 0.0594 0.0633 0.162
Echinococcus granulosus tyrosine protein kinase Lyn 0.0912 0.1132 0.1893
Entamoeba histolytica tyrosin kinase, putative 0.0219 0.0045 0.0393
Schistosoma mansoni serine/threonine kinase 0.0432 0.0379 0.097
Echinococcus granulosus cyclin dependent kinase 9 0.0259 0.0108 0.018
Schistosoma mansoni serine/threonine protein kinase 0.0556 0.0574 0.1467
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0532 0.0536 0.0536
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.0158 0.1355
Loa Loa (eye worm) hypothetical protein 0.047 0.0439 0.0561
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0838 0.1016 0.1847
Schistosoma mansoni ephrin receptor 0.0245 0.0086 0.0219
Schistosoma mansoni serine/threonine protein kinase 0.0448 0.0404 0.1032
Trypanosoma cruzi casein kinase, putative 0.0497 0.0482 0.0876
Trichomonas vaginalis AGC family protein kinase 0.0225 0.0054 0.0465
Onchocerca volvulus 0.0695 0.0791 0.0974
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0832 0.1007 0.1831
Schistosoma mansoni serine/threonine protein kinase 0.0297 0.0168 0.043
Loa Loa (eye worm) hypothetical protein 0.0544 0.0555 0.0709
Plasmodium falciparum glycogen synthase kinase 3 0.0927 0.1156 1
Schistosoma mansoni serine/threonine protein kinase 0.0553 0.0569 0.1455
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0434 0.0383 0.0383
Echinococcus multilocularis serine:threonine protein kinase 38 0.0432 0.0379 0.0379
Schistosoma mansoni serine/threonine protein kinase 0.056 0.058 0.1483
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0407 0.034 0.0434
Trichomonas vaginalis CMGC family protein kinase 0.0228 0.0059 0.0502
Schistosoma mansoni tyrosine kinase 0.0502 0.0489 0.125
Brugia malayi cyclin-dependent kinase 9 0.0259 0.0108 0.0138
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0196 0.0009 0.0016
Echinococcus granulosus STE20 serine:threonine protein kinase 0.057 0.0595 0.0995
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.056 0.058 0.0969
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0407 0.034 0.294
Schistosoma mansoni kinase 0.0326 0.0212 0.0543
Echinococcus granulosus calcium dependent protein kinase 0.0281 0.0143 0.0238
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.1654 0.2297 0.2297
Loa Loa (eye worm) TK protein kinase 0.1301 0.1743 0.2227
Echinococcus granulosus mitogen activated protein kinase 11 0.3696 0.5499 0.9193
Echinococcus granulosus casein kinase i 0.0497 0.0482 0.0805
Schistosoma mansoni neuroglian 0.0238 0.0075 0.0192
Echinococcus multilocularis tyrosine protein kinase Abl 0.1018 0.1299 0.1299
Echinococcus multilocularis TGF beta receptor type 1 0.0693 0.0788 0.0788
Loa Loa (eye worm) hypothetical protein 0.0743 0.0868 0.1109
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0407 0.034 0.0568
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0291 0.0158 0.0288
Giardia lamblia Kinase, PLK 0.0263 0.0114 0.0975
Brugia malayi Protein kinase domain containing protein 0.1896 0.2676 0.3419
Echinococcus multilocularis cyclin dependent kinase 1 0.0377 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.1122 0.1461 0.1868
Entamoeba histolytica PH domain containing protein kinase, putative 0.0594 0.0634 0.5486
Loa Loa (eye worm) TK/FAK protein kinase 0.2712 0.3957 0.5056
Echinococcus multilocularis calcium dependent protein kinase 0.0281 0.0143 0.0143
Brugia malayi Protein kinase domain 0.0285 0.0149 0.019
Trichomonas vaginalis CMGC family protein kinase 0.0228 0.0059 0.0502
Leishmania major protein kinase A catalytic subunit isoform 1 0.056 0.058 0.1054
Loa Loa (eye worm) TK/EGFR protein kinase 0.0819 0.0986 0.126
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0434 0.0383 0.064
Echinococcus multilocularis beta adrenergic receptor kinase 0.024 0.0078 0.0078
Brugia malayi hypothetical protein 0.0498 0.0482 0.0616
Leishmania major protein kinase A catalytic subunit 0.056 0.058 0.1054
Echinococcus granulosus cyclin dependent kinase 1 0.0377 0.0293 0.049
Trichomonas vaginalis CMGC family protein kinase 0.0927 0.1156 0.9885
Trichomonas vaginalis STE family protein kinase 0.0285 0.0149 0.1274
Brugia malayi Protein kinase domain containing protein 0.0363 0.0271 0.0346
Trypanosoma cruzi casein kinase, putative 0.0497 0.0482 0.0876
Loa Loa (eye worm) hypothetical protein 0.0243 0.0083 0.0106
Trichomonas vaginalis AGC family protein kinase 0.0585 0.062 0.5303
Onchocerca volvulus 0.0251 0.0096 0.0082
Schistosoma mansoni cell adhesion molecule 0.0564 0.0587 0.15
Brugia malayi Cam kinase protein 1 0.0407 0.034 0.0434
Trypanosoma cruzi cdc2-related kinase 1 0.0377 0.0293 0.0533
Entamoeba histolytica protein kinase , putative 0.0455 0.0416 0.3597
Giardia lamblia Aurora kinase 0.0455 0.0416 0.3555
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0377 0.0293 0.0374
Trypanosoma brucei protein kinase, putative 0.0198 0.0012 0.0022
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0286 0.0151 0.0193
Echinococcus granulosus casein kinase I alpha 0.0497 0.0482 0.0805
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.2177 0.3116 0.3983
Echinococcus multilocularis raf serine:threonine protein kinase 0.0306 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0238 0.0075 0.0096
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0291 0.0158 0.0288
Trichomonas vaginalis CAMK family protein kinase 0.0333 0.0223 0.1909
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.0158 0.1355
Echinococcus multilocularis roundabout 2 0.0709 0.0813 0.0813
Schistosoma mansoni protein kinase 0.0693 0.0788 0.2015
Loa Loa (eye worm) hypothetical protein 0.0621 0.0675 0.0863
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0525 0.0526 0.0672
Onchocerca volvulus 0.0344 0.0241 0.0268
Echinococcus granulosus titin 0.0297 0.0168 0.0281
Entamoeba histolytica protein kinase, putative 0.0832 0.1007 0.8716
Entamoeba histolytica protein kinase, putative 0.0286 0.0151 0.1305
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0497 0.0482 0.0616
Loa Loa (eye worm) hypothetical protein 0.0732 0.085 0.1086
Loa Loa (eye worm) AGC/PKA protein kinase 0.056 0.058 0.0741
Loa Loa (eye worm) hypothetical protein 0.0195 0.0008 0.001
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0223 0.0052 0.045
Trichomonas vaginalis STE family protein kinase 0.0225 0.0054 0.0465
Echinococcus multilocularis cyclin dependent kinase 9 0.0259 0.0108 0.0108
Echinococcus granulosus serine:threonine protein kinase mig 15 0.1122 0.1461 0.2443
Echinococcus granulosus ephrin type A receptor 4 A 0.0245 0.0086 0.0143
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0309 0.0186 0.0311
Echinococcus multilocularis MAM 0.0224 0.0053 0.0053
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0357 0.0262 0.0335
Echinococcus granulosus calcium activated potassium channel 0.0254 0.0099 0.0166
Echinococcus multilocularis casein kinase I gamma 0.0299 0.0171 0.0171
Echinococcus multilocularis growth factor receptor bound protein 2 0.0286 0.0151 0.0151
Plasmodium falciparum calcium-dependent protein kinase 1 0.0407 0.034 0.294
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0285 0.0149 0.0249
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0233 0.0067 0.0067
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0716 0.0824 0.1054
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0657 0.0733 0.1225
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0532 0.0536 0.0895
Echinococcus multilocularis peroxidasin 0.0213 0.0036 0.0036
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.1861 0.2621 0.3349
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0287 0.0152 0.0194
Echinococcus granulosus tyrosine kinase 0.0344 0.0241 0.0403
Loa Loa (eye worm) hypothetical protein 0.0211 0.0032 0.0041
Loa Loa (eye worm) hypothetical protein 0.0681 0.077 0.0984
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0473 0.0444 0.0567
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.0158 0.1355
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.036 0.0267 0.0341
Echinococcus multilocularis casein kinase I alpha 0.0497 0.0482 0.0482
Leishmania major protein kinase, putative 0.0407 0.034 0.0618
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0211 0.0032 0.0083
Loa Loa (eye worm) AGC/PKA protein kinase 0.056 0.058 0.0741
Brugia malayi probable protein kinase 0.1248 0.1659 0.212
Leishmania major casein kinase, putative 0.0497 0.0482 0.0876
Onchocerca volvulus Serine\/threonine kinase homolog 0.0252 0.0097 0.0082
Echinococcus granulosus protein kinase C gamma type 0.0471 0.0441 0.0737
Trypanosoma brucei aurora B kinase 0.0455 0.0416 0.0756
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0289 0.0155 0.0198
Brugia malayi Fes/CIP4 homology domain containing protein 0.0621 0.0675 0.0863
Echinococcus granulosus casein kinase I delta 0.0497 0.0482 0.0805
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.056 0.058 0.1054
Loa Loa (eye worm) thyroid receptor interactor 0.0621 0.0675 0.0863
Trypanosoma cruzi cdc2-related kinase 3 0.0377 0.0293 0.0533
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0407 0.034 0.034
Trichomonas vaginalis AGC family protein kinase 0.056 0.058 0.4961
Schistosoma mansoni Neurotrimin precursor (hNT) 0.047 0.0439 0.1124
Trichomonas vaginalis AGC family protein kinase 0.0466 0.0433 0.3706
Entamoeba histolytica p21-activated kinase 0.032 0.0203 0.1757
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0252 0.0097 0.0161
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0407 0.034 0.034
Trichomonas vaginalis AGC family protein kinase 0.0585 0.062 0.5303
Schistosoma mansoni nck2/grb4 0.0286 0.0151 0.0385
Schistosoma mansoni protein kinase 0.075 0.0878 0.2246
Brugia malayi protein-tyrosine kinase 0.0661 0.0738 0.0943
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.056 0.058 0.1054
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0407 0.034 0.0568
Loa Loa (eye worm) hypothetical protein 0.0407 0.034 0.0434
Schistosoma mansoni vam6/vps39 related 0.0532 0.0536 0.137
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0225 0.0054 0.0471
Brugia malayi Protein kinase domain containing protein 0.0585 0.062 0.0792
Entamoeba histolytica protein kinase domain containing protein 0.0289 0.0155 0.1339
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0233 0.0067 0.0113
Schistosoma mansoni serine/threonine protein kinase 0.0695 0.0791 0.2024
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0407 0.034 0.0434
Brugia malayi Protein kinase domain containing protein 0.0432 0.0379 0.0485
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0473 0.0444 0.0444
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0786 0.0935 0.0935
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0859 0.1049 0.134
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0309 0.0186 0.0339
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0309 0.0186 0.1612
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.0158 0.0405
Schistosoma mansoni serine/threonine protein kinase 0.043 0.0376 0.0962
Trichomonas vaginalis CAMK family protein kinase 0.0263 0.0114 0.0975
Brugia malayi Protein kinase domain containing protein 0.0299 0.0171 0.0218
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0245 0.0085 0.0738
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.056 0.058 0.1054
Brugia malayi protein kinase C3,putative 0.0328 0.0216 0.0276
Loa Loa (eye worm) TK/FER protein kinase 0.0344 0.0241 0.0308
Schistosoma mansoni serine/threonine protein kinase 0.0377 0.0293 0.0749
Echinococcus multilocularis neuroglian 0.0615 0.0666 0.0666
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0432 0.0379 0.0485
Loa Loa (eye worm) TK/ALK protein kinase 0.3434 0.5089 0.6504
Loa Loa (eye worm) hypothetical protein 0.0425 0.0368 0.047
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0927 0.1156 0.1156
Trypanosoma cruzi cdc2-related kinase 3 0.0377 0.0293 0.0533
Echinococcus multilocularis dual specificity 0.0228 0.0059 0.0059
Brugia malayi Immunoglobulin I-set domain containing protein 0.0211 0.0032 0.0041
Entamoeba histolytica cell division protein kinase 2, putative 0.04 0.033 0.2853
Entamoeba histolytica protein kinase, putative 0.0285 0.0149 0.1289
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0832 0.1007 0.1831
Brugia malayi Protein kinase domain containing protein 0.0357 0.0262 0.0335
Giardia lamblia Kinase, CMGC CLK 0.0838 0.1016 0.8689
Echinococcus granulosus serine/threonine protein kinase 0.0279 0.0139 0.0233
Schistosoma mansoni serine/threonine protein kinase 0.0497 0.0482 0.1232
Onchocerca volvulus 0.5178 0.7825 1
Trichomonas vaginalis STE family protein kinase 0.0264 0.0116 0.0994
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0263 0.0114 0.0207
Loa Loa (eye worm) hypothetical protein 0.0498 0.0482 0.0616
Trypanosoma brucei SNF1-related protein kinases, putative 0.0291 0.0158 0.0288
Brugia malayi Protein kinase c protein 2 0.0288 0.0153 0.0195
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0285 0.0149 0.0149
Schistosoma mansoni protein kinase 0.1861 0.2621 0.6703
Schistosoma mansoni serine/threonine protein kinase 0.1268 0.1691 0.4325
Loa Loa (eye worm) hypothetical protein 0.0211 0.0032 0.0041
Echinococcus multilocularis protein tyrosine kinase 0.2683 0.391 0.391
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0407 0.034 0.294
Echinococcus granulosus protein kinase c iota type 0.0634 0.0697 0.1165
Loa Loa (eye worm) hypothetical protein 0.0537 0.0544 0.0695
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1154 0.1512 0.1932
Loa Loa (eye worm) TK/FER protein kinase 0.0344 0.0241 0.0308
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0283 0.0146 0.0244
Schistosoma mansoni ephrin receptor 0.0211 0.0032 0.0082
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0283 0.0146 0.0187
Entamoeba histolytica protein kinase domain containing protein 0.0219 0.0045 0.0393
Echinococcus granulosus N chimaerin 0.0283 0.0146 0.0244
Echinococcus granulosus serine threonine protein kinase nrc 0.0245 0.0085 0.0143
Brugia malayi Sex muscle abnormal protein 5 0.0286 0.0151 0.0193
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0371 0.0284 0.0475
Entamoeba histolytica casein kinase 1, putative 0.0497 0.0482 0.4169
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.056 0.058 0.0741
Loa Loa (eye worm) hypothetical protein 0.0211 0.0032 0.0041
Echinococcus multilocularis tyrosine kinase 0.0344 0.0241 0.0241
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0377 0.0293 0.0374
Echinococcus granulosus tyrosine protein kinase Fyn 0.0786 0.0935 0.1563
Loa Loa (eye worm) hypothetical protein 0.0671 0.0754 0.0964
Trichomonas vaginalis CMGC family protein kinase 0.0838 0.1016 0.8689
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0927 0.1156 0.2101
Trichomonas vaginalis AGC family protein kinase 0.0432 0.0379 0.3244
Echinococcus multilocularis cyclin dependent kinase 5 0.0377 0.0293 0.0293
Schistosoma mansoni protein kinase 0.0309 0.0186 0.0476
Echinococcus granulosus Immunoglobulin 0.047 0.0439 0.0734
Echinococcus multilocularis serine:threonine protein kinase 3 0.0341 0.0237 0.0237
Loa Loa (eye worm) hypothetical protein 0.1149 0.1504 0.1922
Schistosoma mansoni nephrin 0.0642 0.0709 0.1813
Giardia lamblia Kinase, CK1 Casein kinase 0.0497 0.0482 0.4121
Trypanosoma cruzi aurora B kinase, putative 0.0455 0.0416 0.0756
Echinococcus multilocularis serine:threonine protein kinase 0.0243 0.0083 0.0083
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0377 0.0293 0.0533
Echinococcus granulosus titin 0.0297 0.0168 0.0281
Schistosoma mansoni tyrosine kinase 0.0389 0.0311 0.0796
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0223 0.0052 0.0052
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.0158 0.1355
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.056 0.058 0.5018
Brugia malayi Tyrosine-protein kinase abl-1 0.0887 0.1092 0.1396
Entamoeba histolytica protein kinase, putative 0.0585 0.062 0.5365
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1292 0.1728 0.2208
Schistosoma mansoni tyrosine kinase 0.0685 0.0776 0.1985
Schistosoma mansoni serine/threonine protein kinase 0.0455 0.0416 0.1063
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.1861 0.2621 0.4381
Echinococcus multilocularis basement membrane specific heparan sulfate 0.047 0.0439 0.0439
Brugia malayi Protein kinase domain containing protein 0.0432 0.0379 0.0485
Brugia malayi Protein kinase domain containing protein 0.0287 0.0152 0.0194
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0838 0.1016 0.879
Schistosoma mansoni serine/threonine protein kinase 0.0287 0.0152 0.0389
Schistosoma mansoni vesicular amine transporter 0.047 0.0439 0.1124
Giardia lamblia Kinase, CMGC GSK 0.0927 0.1156 0.9885
Schistosoma mansoni tyrosine kinase 0.1047 0.1344 0.3438
Loa Loa (eye worm) TK/FER protein kinase 0.0344 0.0241 0.0308

Activities

Activity type Activity value Assay description Source Reference
IZ (functional) = 10.3 mm Antimicrobial activity against Escherichia coli ATCC 25922 after 18 hrs by agar well diffusion assay ChEMBL. 25305333

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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