Detailed information for compound 943723

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 553.731 | Formula: C29H51N3O7
  • H donors: 7 H acceptors: 6 LogP: 3.48 Rotable bonds: 18
    Rule of 5 violations (Lipinski): 3
  • SMILES: OC[C@H]1O[C@@H](NC(=O)CCCCCCCCCCCNC(=O)NC23CC4CC(C3)CC(C2)C4)[C@@H]([C@@H]([C@H]1O)O)O
  • InChi: 1S/C29H51N3O7/c33-18-22-24(35)25(36)26(37)27(39-22)31-23(34)10-8-6-4-2-1-3-5-7-9-11-30-28(38)32-29-15-19-12-20(16-29)14-21(13-19)17-29/h19-22,24-27,33,35-37H,1-18H2,(H,31,34)(H2,30,32,38)/t19?,20?,21?,22-,24+,25-,26-,27-,29?/m1/s1
  • InChiKey: RYLZLDBTJOJMIU-OGOWPJDRSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.008 0.0029 0.0031
Brugia malayi Protein kinase domain containing protein 0.0227 0.0167 0.0234
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.8071 0.7519 0.7519
Giardia lamblia Kinase, STE STE20 0.0114 0.0061 0.0139
Echinococcus multilocularis tyrosine protein kinase Abl 0.0057 0.0008 0.0008
Echinococcus granulosus dual specificity mitogen activated protein 0.0114 0.0061 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.1898 0.1734 0.2426
Giardia lamblia GTOR 0.1912 0.1747 0.3993
Loa Loa (eye worm) hypothetical protein 0.0075 0.0025 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0029 0.0041
Loa Loa (eye worm) hypothetical protein 0.008 0.0029 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.1898 0.1734 0.2426
Onchocerca volvulus Peroxidasin homolog 0.0075 0.0025 0.0251
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0579 0.0497 0.0497
Loa Loa (eye worm) hypothetical protein 0.0063 0.0014 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0748 0.0655 0.0654
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0186 0.0129 0.0143
Echinococcus granulosus cell adhesion molecule 0.008 0.0029 0.0029
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0579 0.0497 0.0701
Brugia malayi Cyclin, N-terminal domain containing protein 0.0604 0.052 0.0731
Trichomonas vaginalis cyclins, putative 0.0604 0.052 0.0714
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0034 0.0028
Loa Loa (eye worm) cyclin domain-containing protein 0.0131 0.0077 0.0085
Entamoeba histolytica hypothetical protein 0.0579 0.0497 0.0701
Schistosoma mansoni serine/threonine protein kinase 0.065 0.0564 0.0563
Brugia malayi Protein kinase domain containing protein 0.0063 0.0014 0.0017
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.1499 0.1359 0.7826
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.1062 0.095 0.0949
Loa Loa (eye worm) animal heme peroxidase 0.0075 0.0025 0.0027
Loa Loa (eye worm) hypothetical protein 0.0083 0.0032 0.0034
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0025 0.0034
Echinococcus multilocularis cyclin A3 4 0.0131 0.0077 0.0077
Echinococcus granulosus titin 0.0179 0.0122 0.0122
Echinococcus multilocularis cyclins 0.0543 0.0463 0.0463
Trichomonas vaginalis PIKK family atypical protein kinase 0.1901 0.1736 0.243
Trichomonas vaginalis AGC family protein kinase 0.0092 0.0041 0.0037
Brugia malayi Cyclin, N-terminal domain containing protein 0.0131 0.0077 0.0107
Trichomonas vaginalis cyclins, putative 0.0604 0.052 0.0714
Brugia malayi Immunoglobulin I-set domain containing protein 0.0162 0.0107 0.0149
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1912 0.1747 0.2459
Schistosoma mansoni protein tyrosine phosphatase 0.008 0.0029 0.0028
Echinococcus granulosus cyclin k 0.0131 0.0077 0.0077
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0025 0.0034
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.149 0.1351 0.1902
Echinococcus multilocularis anosmin 1 0.008 0.0029 0.0029
Echinococcus granulosus cyclin G2 0.0131 0.0077 0.0077
Echinococcus granulosus dual specificity testis-specific protein kinase 0.006 0.0011 0.0011
Echinococcus multilocularis cyclin y 0.0131 0.0077 0.0077
Schistosoma mansoni cyclin G 0.0131 0.0077 0.0076
Schistosoma mansoni serine/threonine protein kinase 0.065 0.0564 0.0563
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.1025 0.0915 0.1289
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.2647 0.2435 0.3428
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.1499 0.1359 0.1898
Schistosoma mansoni cyclin B 0.0604 0.052 0.0519
Echinococcus multilocularis Phosphotidylinositol phosphatase PTPRQ 0.008 0.0029 0.0029
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.2647 0.2435 0.3429
Schistosoma mansoni tyrosine kinase 0.0205 0.0147 0.0145
Echinococcus granulosus Netrin receptor DCC 0.008 0.0029 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.1876 0.1713 0.2397
Giardia lamblia Hypothetical protein 0.0543 0.0463 0.1059
Echinococcus multilocularis roundabout 2 0.0218 0.0159 0.0159
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0748 0.0655 0.6896
Echinococcus multilocularis down syndrome cell adhesion 0.0075 0.0025 0.0025
Brugia malayi Immunoglobulin I-set domain containing protein 0.0136 0.0082 0.0113
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0157 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0083 0.0032 0.0034
Trichomonas vaginalis cyclin B, putative 0.0604 0.052 0.0714
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0025 0.0034
Brugia malayi Immunoglobulin I-set domain containing protein 0.0083 0.0032 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.189 0.1726 0.2415
Onchocerca volvulus 0.0075 0.0025 0.0251
Entamoeba histolytica hypothetical protein 0.1604 0.1458 0.2053
Schistosoma mansoni tyrosine kinase 0.0057 0.0008 0.0006
Plasmodium falciparum cyclin 0.0543 0.0463 0.341
Brugia malayi Lethal protein 805 0.008 0.0029 0.0039
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.065 0.0564 0.0631
Trichomonas vaginalis cyclins, putative 0.0604 0.052 0.0714
Plasmodium vivax hypothetical protein 0.0579 0.0497 0.366
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.6477 0.6024 0.8485
Echinococcus granulosus titin 0.0075 0.0025 0.0025
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0085 0.0034 0.0048
Trypanosoma cruzi target of rapamycin kinase 3 0.1901 0.1736 0.2445
Echinococcus multilocularis peroxidasin 0.0083 0.0032 0.0032
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.2647 0.2435 0.2434
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.1604 0.1458 0.5969
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.3347 0.3091 0.4354
Brugia malayi Tyrosine-protein kinase abl-1 0.0057 0.0008 0.0009
Entamoeba histolytica protein kinase domain containing protein 0.006 0.0011 0.0016
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0056 0.0007 0.0006
Echinococcus granulosus Phosphotidylinositol phosphatase PTPRQ 0.008 0.0029 0.0029
Schistosoma mansoni nephrin related 0.0075 0.0025 0.0024
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0075 0.0025 0.0025
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0057 0.0008 0.0006
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.4407 0.4085 0.4085
Schistosoma mansoni nephrin 0.0211 0.0152 0.0151
Echinococcus granulosus serine:threonine protein kinase SMG1 0.1176 0.1057 0.1057
Plasmodium vivax protein kinase Crk2 0.065 0.0564 0.4151
Brugia malayi Cyclin, N-terminal domain containing protein 0.0131 0.0077 0.0107
Echinococcus granulosus contactin 0.0162 0.0107 0.0107
Trichomonas vaginalis PIKK family atypical protein kinase 0.1212 0.1091 0.1519
Echinococcus multilocularis cyclin k 0.0131 0.0077 0.0077
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.5865 0.5451 0.7672
Loa Loa (eye worm) cyclin domain-containing protein 0.0131 0.0077 0.0085
Onchocerca volvulus Tyrosine kinase homolog 0.028 0.0217 0.2279
Giardia lamblia Kinase, CMGC CDK 0.065 0.0564 0.1289
Schistosoma mansoni septate junction protein 0.0083 0.0032 0.0031
Schistosoma mansoni fkbp-rapamycin associated protein 0.1176 0.1057 0.1055
Brugia malayi SRC-1 0.0092 0.0041 0.0056
Trypanosoma cruzi Protein kinase B 0.0051 0.0002 0.0003
Echinococcus granulosus G1:S specific cyclin D1 0.0131 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0075 0.0025 0.0027
Onchocerca volvulus 0.008 0.0029 0.0295
Plasmodium vivax glycogen synthase kinase 3, putative 0.1062 0.095 0.6987
Plasmodium falciparum phosphatidylinositol 3-kinase 0.1499 0.1359 1
Echinococcus multilocularis hemicentin 1 0.0083 0.0032 0.0032
Echinococcus multilocularis tyrosine protein kinase Srms 0.0085 0.0035 0.0035
Echinococcus granulosus protein kinase shaggy 0.1062 0.095 0.095
Trichomonas vaginalis cyclin D, putative 0.0543 0.0463 0.0634
Echinococcus granulosus cyclins 0.0543 0.0463 0.0463
Echinococcus granulosus tyrosine protein kinase Blk 0.0085 0.0035 0.0035
Brugia malayi Immunoglobulin I-set domain containing protein 0.0179 0.0122 0.017
Loa Loa (eye worm) hypothetical protein 0.0061 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0579 0.0497 0.0556
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.1901 0.1736 0.5798
Schistosoma mansoni titin 0.0083 0.0032 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0579 0.0497 0.0682
Brugia malayi Immunoglobulin I-set domain containing protein 0.0232 0.0172 0.0241
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0579 0.0497 0.2824
Onchocerca volvulus 0.008 0.0029 0.0295
Echinococcus granulosus cyclin dependent kinase 5 0.065 0.0564 0.0564
Toxoplasma gondii cyclin dependent kinase binding protein 0.0131 0.0077 0.0385
Entamoeba histolytica hypothetical protein 0.0579 0.0497 0.0701
Trypanosoma cruzi cyclin 6, putative 0.0604 0.052 0.0733
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0077 0.0089
Echinococcus granulosus serine protein kinase ATM 0.1604 0.1458 0.1458
Trichomonas vaginalis PIKK family atypical protein kinase 0.1901 0.1736 0.243
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0041 0.004
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.1499 0.1359 0.1359
Onchocerca volvulus 0.0075 0.0025 0.0251
Loa Loa (eye worm) hypothetical protein 0.0075 0.0025 0.0027
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.1727 0.1573 0.3596
Brugia malayi Protein kinase domain containing protein 0.0092 0.0041 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.1912 0.1747 0.2445
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.7625 0.71 1
Echinococcus granulosus leucine rich repeat containing protein 4 0.0075 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.1279 0.1153 0.1291
Entamoeba histolytica cyclin family protein 0.0543 0.0463 0.0653
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0205 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0056 0.0007 0.0006
Onchocerca volvulus 0.0092 0.0041 0.0421
Brugia malayi Cyclin C 0.0131 0.0077 0.0107
Echinococcus multilocularis tyrosine protein kinase otk 0.0083 0.0032 0.0032
Echinococcus multilocularis neuroglian 0.0162 0.0107 0.0107
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.2067 0.1892 0.2665
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0051 0.0002 0.0003
Echinococcus multilocularis Netrin receptor DCC 0.008 0.0029 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.059 0.0508 0.0697
Trichomonas vaginalis PIKK family atypical protein kinase 0.149 0.1351 0.1886
Schistosoma mansoni hypothetical protein 0.0075 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0083 0.0032 0.0034
Loa Loa (eye worm) projectin 0.0155 0.01 0.011
Plasmodium vivax cyclin 4, putative 0.0131 0.0077 0.0569
Echinococcus multilocularis Fibronectin type III domain containing protein 0.008 0.0029 0.0029
Loa Loa (eye worm) TK protein kinase 0.0085 0.0035 0.0037
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0579 0.0497 0.0699
Onchocerca volvulus 0.008 0.0029 0.0295
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0085 0.0034 0.0048
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0082 0.0032 0.0034
Schistosoma mansoni neuroglian 0.0162 0.0107 0.0105
Trichomonas vaginalis cyclin B, putative 0.0131 0.0077 0.0089
Loa Loa (eye worm) hypothetical protein 0.0136 0.0082 0.009
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.7625 0.71 1
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.008 0.0029 0.0039
Giardia lamblia Phosphatidylinositol 4-kinase 0.0579 0.0497 0.1137
Trichomonas vaginalis CMGC family protein kinase 0.1062 0.095 0.132
Schistosoma mansoni cell adhesion molecule 0.0162 0.0107 0.0105
Schistosoma mansoni hypothetical protein 0.0131 0.0077 0.0076
Echinococcus granulosus cyclins 0.0543 0.0463 0.0463
Loa Loa (eye worm) TK/INSR protein kinase 0.0252 0.0191 0.0213
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0579 0.0497 0.2007
Echinococcus multilocularis tyrosine protein kinase HCK 0.0072 0.0022 0.0022
Onchocerca volvulus 0.0168 0.0112 0.1171
Echinococcus granulosus usherin 0.008 0.0029 0.0029
Echinococcus granulosus cyclin dependent kinase 1 0.065 0.0564 0.0564
Loa Loa (eye worm) AUR protein kinase 0.0092 0.0041 0.0044
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.065 0.0564 0.1859
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0092 0.0041 0.0057
Schistosoma mansoni tyrosine kinase 0.0289 0.0225 0.0224
Trichomonas vaginalis CMGC family protein kinase 0.065 0.0564 0.0776
Giardia lamblia Cyclin A 0.0543 0.0463 0.1059
Brugia malayi cyclin fold protein 1 variant b 0.0131 0.0077 0.0107
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0092 0.0041 0.0041
Echinococcus granulosus G1Y162 protein 0.008 0.0029 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0032 0.0025
Entamoeba histolytica protein kinase, putative 0.0064 0.0014 0.002
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0155 0.01 0.01
Plasmodium vivax hypothetical protein, conserved 0.0131 0.0077 0.0569
Echinococcus granulosus cyclin y 0.0131 0.0077 0.0077
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.3347 0.3091 0.4353
Echinococcus granulosus fibroblast growth factor receptor 4 0.0157 0.0102 0.0102
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0061 0.0012 0.0012
Brugia malayi Immunoglobulin I-set domain containing protein 0.0087 0.0036 0.0049
Echinococcus granulosus down syndrome cell adhesion 0.0075 0.0025 0.0025
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0092 0.0041 0.0057
Onchocerca volvulus Netrin receptor homolog 0.0075 0.0025 0.0251
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0083 0.0032 0.0034
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.07 0.0611 0.0611
Onchocerca volvulus 0.0075 0.0025 0.0251
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.0131 0.0077 0.0569
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0579 0.0497 0.2824
Mycobacterium tuberculosis Conserved hypothetical protein 0.0579 0.0497 0.5
Schistosoma mansoni tyrosine kinase 0.0252 0.0191 0.019
Brugia malayi cell division control protein 2 homolog 0.065 0.0564 0.0793
Schistosoma mansoni serine/threonine protein kinase 0.03 0.0236 0.0234
Schistosoma mansoni hypothetical protein 0.008 0.0029 0.0028
Schistosoma mansoni roundabout 0.0083 0.0032 0.0031
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0579 0.0497 0.366
Leishmania major mitotic cyclin, putative 0.0131 0.0077 0.0223
Loa Loa (eye worm) hypothetical protein 0.0139 0.0084 0.0093
Echinococcus multilocularis titin 0.0075 0.0025 0.0025
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0185 0.0128 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0597 0.0514 0.0705
Loa Loa (eye worm) hypothetical protein 0.0139 0.0084 0.0093
Loa Loa (eye worm) hypothetical protein 0.0136 0.0082 0.009
Entamoeba histolytica cyclin, domain containing protein 0.0131 0.0077 0.0109
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.008 0.0029 0.0029
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0075 0.0025 0.0025
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.7045 0.6557 0.9235
Trichomonas vaginalis cyclins, putative 0.0131 0.0077 0.0089
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0332 0.0266 0.0266
Trichomonas vaginalis PIKK family atypical protein kinase 0.1876 0.1713 0.2397
Toxoplasma gondii aurora kinase 0.0092 0.0041 0.0171
Trypanosoma brucei target of rapamycin kinase 3, putative 0.1901 0.1736 0.7118
Echinococcus multilocularis cyclin y 0.0131 0.0077 0.0077
Giardia lamblia Hypothetical protein 0.0131 0.0077 0.0177
Schistosoma mansoni tyrosine kinase 0.0057 0.0008 0.0006
Echinococcus granulosus Fibronectin type III 0.008 0.0029 0.0029
Echinococcus multilocularis titin 0.0075 0.0025 0.0025
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.008 0.0029 0.0029
Onchocerca volvulus 0.0075 0.0025 0.0251
Echinococcus multilocularis cyclins 0.0543 0.0463 0.0463
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0057 0.0008 0.0008
Giardia lamblia G2/mitotic-specific cyclin B 0.0604 0.052 0.1189
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0075 0.0025 0.0027
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0162 0.0107 0.0105
Trichomonas vaginalis cyclin A, putative 0.0131 0.0077 0.0089
Brugia malayi p70 ribosomal S6 kinase beta 0.0061 0.0012 0.0015
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0034 0.0028
Echinococcus granulosus cyclins 0.0131 0.0077 0.0077
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.2647 0.2435 1
Leishmania major phosphatidylinositol 3-related kinase, putative 0.219 0.2007 0.6707
Plasmodium falciparum protein kinase, putative 0.006 0.0011 0.0081
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.008 0.0029 0.0039
Trichomonas vaginalis cyclin D, putative 0.0543 0.0463 0.0634
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0131 0.0077 0.0569
Loa Loa (eye worm) hypothetical protein 0.0083 0.0032 0.0034
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0075 0.0025 0.0025
Leishmania major hypothetical protein, conserved 0.008 0.0029 0.0061
Plasmodium vivax cyclin homologue, putative 0.0131 0.0077 0.0569
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.1291 0.1164 0.4757
Loa Loa (eye worm) phosphatidylinositol 3 0.2067 0.1892 0.2119
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0085 0.0034 0.0135
Echinococcus granulosus Immunoglobulin 0.0056 0.0007 0.0007
Onchocerca volvulus 0.1062 0.095 1
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.008 0.0029 0.0028
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0087 0.0036 0.0036
Onchocerca volvulus 0.008 0.0029 0.0295
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0041 0.0039
Echinococcus multilocularis dual specificity testis specific protein kinase 0.006 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0597 0.0514 0.0705
Loa Loa (eye worm) hypothetical protein 0.0075 0.0025 0.0027
Trypanosoma cruzi CYC2-like cyclin, putative 0.0604 0.052 0.0733
Echinococcus granulosus roundabout 2 0.0162 0.0107 0.0107
Brugia malayi Protein kinase domain containing protein 0.0064 0.0014 0.0018
Schistosoma mansoni titin 0.0075 0.0025 0.0024
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0579 0.0497 0.0701
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0131 0.0077 0.0077
Echinococcus granulosus tyrosine protein kinase shark 0.005 0.0001 0.0001
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0092 0.0041 0.0041
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1499 0.1359 0.1358
Onchocerca volvulus 0.008 0.0029 0.0295
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0085 0.0034 0.0048
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0227 0.0167 0.0186
Plasmodium vivax hypothetical protein, conserved 0.0579 0.0497 0.366
Entamoeba histolytica protein kinase, putative 0.0072 0.0022 0.0032
Loa Loa (eye worm) hypothetical protein 0.0155 0.01 0.011
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0034 0.0028
Brugia malayi Cyclin, N-terminal domain containing protein 0.0604 0.052 0.0731
Loa Loa (eye worm) cyclin domain-containing protein 0.0131 0.0077 0.0085
Leishmania major hypothetical protein, unknown function 0.0579 0.0497 0.1635
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 1.0719 1 1
Trypanosoma cruzi cdc2-related kinase 3 0.065 0.0564 0.0795
Echinococcus multilocularis mitogen activated protein kinase 3 0.0085 0.0034 0.0034
Schistosoma mansoni serine/threonine-protein kinase 0.0051 0.0002 0.0001
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.2647 0.2435 0.3416
Schistosoma mansoni protein kinase 0.006 0.0011 0.001
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0085 0.0035 0.0035
Brugia malayi Fibronectin type III domain containing protein 0.008 0.0029 0.0039
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0092 0.0041 0.0041
Trichomonas vaginalis cyclins, putative 0.0131 0.0077 0.0089
Loa Loa (eye worm) raf kinase 0.0263 0.0201 0.0224
Schistosoma mansoni hemicentin 0.0155 0.01 0.0099
Echinococcus granulosus Cyclin L1 0.0131 0.0077 0.0077
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.5865 0.5451 0.7672
Schistosoma mansoni titin 0.0075 0.0025 0.0024
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0075 0.0025 0.0025
Echinococcus granulosus serine/threonine protein kinase 0.0051 0.0002 0.0002
Brugia malayi Protein kinase domain containing protein 0.065 0.0564 0.0793
Trypanosoma brucei cyclin 3 0.0131 0.0077 0.0273
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0155 0.01 0.011
Brugia malayi Animal haem peroxidase family protein 0.0075 0.0025 0.0034
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0579 0.0497 0.0701
Onchocerca volvulus 0.0075 0.0025 0.0251
Mycobacterium leprae conserved hypothetical protein 0.0579 0.0497 0.5
Echinococcus multilocularis cyclins 0.0543 0.0463 0.0463
Loa Loa (eye worm) hypothetical protein 0.0075 0.0025 0.0027
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0748 0.0655 0.0733
Loa Loa (eye worm) hypothetical protein 0.4407 0.4085 0.4576
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0748 0.0655 0.0655
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0131 0.0077 0.0077
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0114 0.0061 0.0206
Echinococcus multilocularis Zinc finger, PHD finger 0.1499 0.1359 0.1359
Onchocerca volvulus Protein CNPPD1 homolog 0.0131 0.0077 0.0802
Toxoplasma gondii AGC kinase 0.0061 0.0012 0.0005
Echinococcus granulosus cyclin y 0.0131 0.0077 0.0077
Echinococcus granulosus tyrosine protein kinase ABL1 0.005 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.1025 0.0915 0.1024
Echinococcus granulosus tyrosine kinase 0.005 0.0001 0.0001
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0056 0.0007 0.0006
Echinococcus granulosus nephrin 0.0155 0.01 0.01
Brugia malayi Disorganized muscle protein 1 0.0075 0.0025 0.0034
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.8071 0.7519 0.7519
Echinococcus granulosus cyclin A3 4 0.0131 0.0077 0.0077
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.1912 0.1747 0.1746
Schistosoma mansoni slit 0.0075 0.0025 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0579 0.0497 0.0682
Echinococcus multilocularis c src tyrosine kinase 0.0057 0.0008 0.0008
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.008 0.0029 0.0031
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.1499 0.1359 0.1914
Echinococcus granulosus tyrosine protein kinase Fyn 0.0092 0.0041 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0077 0.0089
Echinococcus granulosus Phosphotidylinositol phosphatase PTPRQ 0.008 0.0029 0.0029
Brugia malayi hypothetical protein 0.0136 0.0082 0.0113
Echinococcus multilocularis insulin receptor 0.0252 0.0191 0.0191
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0025 0.0034
Echinococcus granulosus tyrosine protein kinase HCK 0.0072 0.0022 0.0022
Onchocerca volvulus 0.0075 0.0025 0.0251
Brugia malayi serine/threonine-protein kinase 6 0.0092 0.0041 0.0055
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0075 0.0025 0.0025
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0085 0.0034 0.0037
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.008 0.0029 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.1198 0.1078 0.15
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.3347 0.3091 0.3091
Echinococcus multilocularis roundabout 2 0.0162 0.0107 0.0107
Brugia malayi Cyclin, N-terminal domain containing protein 0.0131 0.0077 0.0107
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0602 0.0518 0.2093
Loa Loa (eye worm) lethal protein 805 0.008 0.0029 0.0031
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.1499 0.1359 0.5561
Leishmania major phosphatidylinositol 3-kinase, putative 0.1499 0.1359 0.453
Brugia malayi Immunoglobulin I-set domain containing protein 0.0155 0.01 0.0139
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.7625 0.71 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0083 0.0032 0.0043
Brugia malayi Prion-like- 0.0075 0.0025 0.0034
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0162 0.0107 0.0107
Onchocerca volvulus 0.0092 0.0041 0.0421
Echinococcus granulosus neuroglian 0.0162 0.0107 0.0107
Entamoeba histolytica PH domain containing protein kinase, putative 0.0051 0.0002 0.0003
Trypanosoma cruzi cyclin, putative 0.0604 0.052 0.0733
Trichomonas vaginalis cyclin B3, putative 0.0131 0.0077 0.0089
Schistosoma mansoni titin 0.0075 0.0025 0.0024
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0025 0.0034
Brugia malayi protein unc-22 0.0179 0.0122 0.017
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.1176 0.1057 0.1488
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0092 0.0041 0.0041
Echinococcus multilocularis cyclin dependent kinase 1 0.065 0.0564 0.0564
Loa Loa (eye worm) hypothetical protein 0.0604 0.052 0.0582
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1062 0.095 0.1063
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.065 0.0564 0.0564
Trichomonas vaginalis cyclin D, putative 0.0131 0.0077 0.0089
Schistosoma mansoni tyrosine kinase 0.0092 0.0041 0.004
Leishmania major phosphatidylinositol 4-kinase, putative 0.0579 0.0497 0.1635
Echinococcus granulosus twitchin 0.0155 0.0099 0.0099
Entamoeba histolytica protein kinase domain containing protein 0.0092 0.0041 0.0057
Echinococcus granulosus anosmin 1 0.008 0.0029 0.0029
Trichomonas vaginalis cyclin B3, putative 0.0131 0.0077 0.0089
Echinococcus multilocularis cyclins 0.0543 0.0463 0.0463
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0041 0.0038
Trichomonas vaginalis cyclins, putative 0.0604 0.052 0.0714
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0077 0.0089
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0579 0.0497 0.366
Brugia malayi serine/threonine protein kinase 6 0.0092 0.0041 0.0055
Loa Loa (eye worm) hypothetical protein 0.0627 0.0542 0.0606
Leishmania major phosphatidylinositol kinase, putative 0.0579 0.0497 0.1635
Echinococcus multilocularis cyclin b3 0.0543 0.0463 0.0463
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.0136 0.0082 0.009
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0092 0.0041 0.0041
Schistosoma mansoni cell adhesion molecule 0.0075 0.0025 0.0024
Brugia malayi Protein kinase domain containing protein 0.0252 0.0191 0.0267
Echinococcus granulosus titin 0.0075 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0075 0.0025 0.0027
Onchocerca volvulus 0.0604 0.052 0.5472
Loa Loa (eye worm) hypothetical protein 0.008 0.0029 0.0031
Brugia malayi Leucine Rich Repeat family protein 0.0075 0.0025 0.0034
Trypanosoma cruzi Fibronectin type III domain containing protein, putative 0.008 0.0029 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.1901 0.1736 0.243
Entamoeba histolytica protein kinase , putative 0.0092 0.0041 0.0057
Echinococcus multilocularis roundabout 2 0.0162 0.0107 0.0107
Echinococcus granulosus aurora kinase A 0.0092 0.0041 0.0041
Brugia malayi Protein kinase domain containing protein 0.0082 0.0032 0.0043
Giardia lamblia Kinase, CMGC GSK 0.1062 0.095 0.2171
Echinococcus granulosus insulin growth factor binding 0.0075 0.0025 0.0025
Echinococcus multilocularis cell adhesion molecule 0.008 0.0029 0.0029
Schistosoma mansoni protein kinase 0.0092 0.0041 0.0039
Brugia malayi Cyclin, N-terminal domain containing protein 0.0131 0.0077 0.0107
Echinococcus multilocularis anosmin 1 0.008 0.0029 0.0029
Brugia malayi Protein kinase domain containing protein 0.0124 0.0071 0.0098
Brugia malayi Immunoglobulin I-set domain containing protein 0.0083 0.0032 0.0043
Trichomonas vaginalis STE family protein kinase 0.0114 0.0061 0.0066
Trichomonas vaginalis cyclins, putative 0.0543 0.0463 0.0634
Trichomonas vaginalis PIKK family atypical protein kinase 0.189 0.1726 0.2415
Echinococcus granulosus tyrosine protein kinase Fps85D 0.005 0.0001 0.0001
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.1912 0.1747 0.7161
Loa Loa (eye worm) phosphatidylinositol 3 0.219 0.2007 0.2248
Onchocerca volvulus 0.008 0.0029 0.0295
Trypanosoma brucei cdc2-related kinase 3 0.065 0.0564 0.2282
Echinococcus multilocularis hemicentin 1 0.0083 0.0032 0.0032
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.2647 0.2435 0.3429
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0579 0.0497 0.366
Echinococcus multilocularis tyrosine protein kinase shark 0.005 0.0001 0.0001
Brugia malayi FAT domain containing protein 0.07 0.0611 0.0858
Brugia malayi Immunoglobulin I-set domain containing protein 0.0155 0.01 0.0139
Loa Loa (eye worm) disorganized muscle protein 1 0.0075 0.0025 0.0027
Schistosoma mansoni hypothetical protein 0.0155 0.01 0.0099
Loa Loa (eye worm) CAMK protein kinase 0.0179 0.0122 0.0135
Schistosoma mansoni tripartite motif protein trim9 0.008 0.0029 0.0028
Onchocerca volvulus 0.008 0.0029 0.0295
Brugia malayi Cyclin, N-terminal domain containing protein 0.331 0.3057 0.4304
Echinococcus multilocularis twitchin 0.0099 0.0047 0.0047
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.1604 0.1458 0.1457
Schistosoma mansoni tyrosine kinase 0.0205 0.0147 0.0145
Echinococcus multilocularis neuroglian 0.0131 0.0077 0.0077
Schistosoma mansoni hypothetical protein 0.0075 0.0025 0.0024
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.065 0.0564 0.0631
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0025 0.0034
Loa Loa (eye worm) TK/ROR protein kinase 0.0138 0.0084 0.0093
Loa Loa (eye worm) hypothetical protein 0.0131 0.0077 0.0085
Loa Loa (eye worm) hypothetical protein 0.0131 0.0077 0.0085
Plasmodium falciparum serine/threonine protein kinase, putative 0.0092 0.0041 0.0298
Trichomonas vaginalis PIKK family atypical protein kinase 0.1887 0.1723 0.2411
Echinococcus multilocularis titin 0.0179 0.0122 0.0122
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0085 0.0035 0.0035
Loa Loa (eye worm) UNCoordinated family member 0.008 0.0029 0.0031
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0025 0.0034
Brugia malayi Furin-like cysteine rich region family protein 0.0289 0.0225 0.0316
Loa Loa (eye worm) hypothetical protein 0.0087 0.0036 0.0039
Brugia malayi Fibronectin type III domain containing protein 0.0136 0.0082 0.0113
Brugia malayi Cyclin, N-terminal domain containing protein 0.0679 0.0591 0.083
Schistosoma mansoni factor for adipocyte differentiation 0.008 0.0029 0.0028
Giardia lamblia Kinase, CMGC GSK 0.1062 0.095 0.2171
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0034 0.0028
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.0131 0.0077 0.0273
Toxoplasma gondii hypothetical protein 0.0412 0.0341 0.1913
Onchocerca volvulus Cyclin L homolog 0.0131 0.0077 0.0802
Schistosoma mansoni factor for adipocyte differentiation 0.008 0.0029 0.0028
Trichomonas vaginalis CMGC family protein kinase 0.065 0.0564 0.0776
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0268 0.0206 0.023
Loa Loa (eye worm) hypothetical protein 0.0075 0.0025 0.0027
Brugia malayi Prion-like- 0.0075 0.0025 0.0034
Schistosoma mansoni tyrosine kinase 0.0252 0.0191 0.019
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0025 0.0034
Toxoplasma gondii FATC domain-containing protein 0.1604 0.1458 0.84
Entamoeba histolytica PH domain containing protein kinase, putative 0.0051 0.0002 0.0003
Schistosoma mansoni myosin-binding protein-related 0.0155 0.01 0.0099
Schistosoma mansoni phosphatidylinositol 4-kinase 0.1499 0.1359 0.1358
Echinococcus granulosus tyrosine protein kinase otk 0.0083 0.0032 0.0032
Echinococcus granulosus tyrosine protein kinase Src42A 0.0092 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.008 0.0029 0.0031
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0604 0.052 0.1711
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0083 0.0032 0.0324
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0085 0.0034 0.0096
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.7625 0.71 1
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0167 0.0166
Schistosoma mansoni titin 0.0075 0.0025 0.0024
Schistosoma mansoni cyclin l 0.0131 0.0077 0.0076
Onchocerca volvulus 0.008 0.0029 0.0295
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.3259 0.3009 0.4237
Echinococcus granulosus cyclins 0.0543 0.0463 0.0463
Trichomonas vaginalis conserved hypothetical protein 0.07 0.0611 0.0842
Schistosoma mansoni g1/s-specific cyclin C 0.0131 0.0077 0.0076
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0579 0.0497 0.0699
Brugia malayi Cyclin, N-terminal domain containing protein 0.0131 0.0077 0.0107
Onchocerca volvulus Cyclin L homolog 0.0131 0.0077 0.0802
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0131 0.0077 0.0085
Loa Loa (eye worm) hypothetical protein 0.0075 0.0025 0.0027
Echinococcus granulosus cyclin B 0.0604 0.052 0.052
Echinococcus multilocularis Fibronectin, type III 0.008 0.0029 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0041 0.0038
Trichomonas vaginalis cyclin B, putative 0.0131 0.0077 0.0089
Trypanosoma brucei protein kinase, putative 0.0085 0.0034 0.0096
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.07 0.0611 0.0611
Trichomonas vaginalis cyclin B, putative 0.0543 0.0463 0.0634
Brugia malayi Peroxidasin 0.0083 0.0032 0.0043
Echinococcus multilocularis dual specificity mitogen activated protein 0.0114 0.0061 0.0061
Echinococcus multilocularis cyclin G2 0.0131 0.0077 0.0077
Echinococcus granulosus mitogen activated protein kinase 3 0.0085 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0075 0.0025 0.0027
Entamoeba histolytica protein kinase, putative 0.0092 0.0041 0.0057
Brugia malayi Lethal protein 805 0.008 0.0029 0.0039
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1876 0.1713 0.702
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0092 0.0041 0.0041
Schistosoma mansoni titin 0.0179 0.0122 0.0121
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0114 0.0061 0.0067
Echinococcus granulosus insulin receptor 0.0252 0.0191 0.0191
Echinococcus multilocularis 0.0579 0.0497 0.0497
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0092 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0075 0.0025 0.0027
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.008 0.0029 0.0029
Onchocerca volvulus 0.008 0.0029 0.0295
Echinococcus granulosus lachesin 0.0083 0.0032 0.0032
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.1912 0.1747 0.1747
Schistosoma mansoni cyclin d 0.0131 0.0077 0.0076
Loa Loa (eye worm) hypothetical protein 0.008 0.0029 0.0031
Trypanosoma cruzi cyclin, putative 0.0604 0.052 0.0733
Echinococcus granulosus activin receptor type 0.006 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.1898 0.1734 0.2426
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0075 0.0025 0.0034
Echinococcus multilocularis cyclin 0.0131 0.0077 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.219 0.2007 0.2812
Trypanosoma cruzi cdc2-related kinase 1 0.065 0.0564 0.0795
Echinococcus multilocularis Immunoglobulin 0.0056 0.0007 0.0007
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1604 0.1458 0.2052
Onchocerca volvulus Putative titin 0.0075 0.0025 0.0251
Leishmania major phosphatidylinositol 3-kinase, putative 0.1876 0.1713 0.5719
Entamoeba histolytica protein kinase domain containing protein 0.1062 0.095 0.1337
Schistosoma mansoni hypothetical protein 0.0075 0.0025 0.0024
Echinococcus granulosus titin 0.0179 0.0122 0.0122
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0082 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0075 0.0025 0.0027
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0579 0.0497 0.366
Trypanosoma brucei rac serine-threonine kinase, putative 0.0064 0.0014 0.0013
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.1499 0.1359 0.453
Loa Loa (eye worm) hypothetical protein 0.008 0.0029 0.0031
Echinococcus multilocularis tyrosine protein kinase Blk 0.0085 0.0035 0.0035
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0057 0.0008 0.0008
Brugia malayi hypothetical protein 0.0131 0.0077 0.0107
Brugia malayi MAP kinase sur-1 0.0085 0.0034 0.0047
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.1499 0.1359 0.1914
Trichomonas vaginalis PIKK family atypical protein kinase 0.1604 0.1458 0.2037
Onchocerca volvulus 0.0579 0.0497 0.5232
Echinococcus multilocularis transfer RNA-Phe 0.0155 0.01 0.01
Leishmania major cyclin 0.0604 0.052 0.1711
Plasmodium falciparum protein kinase 5 0.065 0.0564 0.4151
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0056 0.0007 0.0007
Schistosoma mansoni receptor protein tyrosine phosphatase 0.008 0.0029 0.0028
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.2647 0.2435 0.3416
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.006 0.0011 0.0016
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0083 0.0032 0.0031
Loa Loa (eye worm) cyclin domain-containing protein 0.331 0.3057 0.3424
Trypanosoma cruzi Fibronectin type III domain containing protein, putative 0.008 0.0029 0.0041
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0092 0.0041 0.0041
Schistosoma mansoni nephrin 0.0162 0.0107 0.0105
Echinococcus granulosus Netrin receptor DCC 0.008 0.0029 0.0029
Brugia malayi Prion-like- 0.0075 0.0025 0.0034
Schistosoma mansoni hypothetical protein 0.0579 0.0497 0.0496
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0075 0.0025 0.0027
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0092 0.0041 0.0041
Schistosoma mansoni cell adhesion molecule 0.0155 0.01 0.0099
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0085 0.0034 0.0048
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0092 0.0041 0.0041
Echinococcus granulosus cyclin t1 0.0131 0.0077 0.0077
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0332 0.0266 0.0266
Loa Loa (eye worm) hypothetical protein 0.0083 0.0032 0.0034
Echinococcus granulosus raf serine:threonine protein kinase 0.03 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0075 0.0025 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.1887 0.1723 0.2411
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.7625 0.71 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0087 0.0036 0.0039
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.1912 0.1747 0.246
Trichomonas vaginalis conserved hypothetical protein 0.1279 0.1153 0.1608
Leishmania major protein kinase, putative 0.0092 0.0041 0.0099
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0162 0.0107 0.0118
Loa Loa (eye worm) AUR protein kinase 0.0092 0.0041 0.0044
Echinococcus multilocularis Immunoglobulin 0.0056 0.0007 0.0007
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0032 0.0025
Loa Loa (eye worm) hypothetical protein 0.07 0.0611 0.0683
Trypanosoma brucei protein kinase, putative 0.1062 0.095 0.3872
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0162 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.008 0.0029 0.0031
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0083 0.0032 0.0032
Plasmodium falciparum cyclin 1 0.0131 0.0077 0.0569
Schistosoma mansoni tyrosine kinase 0.0157 0.0102 0.01
Brugia malayi serine/threonine kinase 12 0.0092 0.0041 0.0055
Brugia malayi Immunoglobulin I-set domain containing protein 0.0155 0.01 0.0139
Loa Loa (eye worm) hypothetical protein 0.008 0.0029 0.0031
Giardia lamblia Hypothetical protein 0.0131 0.0077 0.0177
Echinococcus multilocularis titin 0.008 0.0029 0.0029
Brugia malayi hypothetical protein 0.008 0.0029 0.0039
Brugia malayi Immunoglobulin I-set domain containing protein 0.0268 0.0206 0.0289
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0157 0.0102 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.1305 0.1177 0.1641
Giardia lamblia Aurora kinase 0.0092 0.0041 0.0093
Echinococcus multilocularis tyrosine kinase 0.005 0.0001 0.0001
Brugia malayi kettin 0.0075 0.0025 0.0034
Schistosoma mansoni tyrosine kinase 0.0168 0.0112 0.0111
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.1912 0.1747 0.246
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0579 0.0497 0.366
Echinococcus granulosus epidermal growth factor receptor 0.0205 0.0147 0.0147
Trypanosoma brucei cyclin 9 0.0131 0.0077 0.0273
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.2647 0.2435 0.3416
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0114 0.0061 0.0086
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0162 0.0107 0.0107
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0085 0.0034 0.0078
Brugia malayi myotactin form A 0.008 0.0029 0.0039
Schistosoma mansoni protein kinase 0.006 0.0011 0.001
Brugia malayi SPRY domain containing protein 0.008 0.0029 0.0039
Entamoeba histolytica cyclin, putative 0.0543 0.0463 0.0653
Schistosoma mansoni hypothetical protein 0.0075 0.0025 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.1876 0.1713 0.2397
Loa Loa (eye worm) SRC-1 0.0092 0.0041 0.0044
Entamoeba histolytica cell division protein kinase 2, putative 0.065 0.0564 0.0795
Loa Loa (eye worm) phosphatidylinositol 3 0.0579 0.0497 0.0556
Entamoeba histolytica cyclin family protein 0.0543 0.0463 0.0653
Echinococcus granulosus hemicentin 1 0.0083 0.0032 0.0032
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0162 0.0107 0.0107
Trichomonas vaginalis cyclin B, putative 0.0604 0.052 0.0714
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0579 0.0497 0.2007
Loa Loa (eye worm) hypothetical protein 0.0056 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0056 0.0007 0.0006
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0579 0.0497 0.2824
Loa Loa (eye worm) hypothetical protein 0.008 0.0029 0.0031
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0579 0.0497 0.0701
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0131 0.0077 0.0385
Trypanosoma brucei mitotic cyclin 6 0.0604 0.052 0.21
Echinococcus granulosus cyclin B3 1 0.0543 0.0463 0.0463
Brugia malayi intracellular kinase 0.1062 0.095 0.1336
Loa Loa (eye worm) hypothetical protein 0.0155 0.01 0.011
Giardia lamblia Kinase, CDC7 0.0092 0.0041 0.0094
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.1062 0.095 0.5449
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.1912 0.1747 0.246
Loa Loa (eye worm) myotactin form A 0.008 0.0029 0.0031
Trypanosoma cruzi cyclin 9, putative 0.0131 0.0077 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.1176 0.1057 0.1471
Onchocerca volvulus 0.0179 0.0122 0.1271
Echinococcus granulosus tyrosine protein kinase Lyn 0.0116 0.0063 0.0063
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 1.0719 1 1
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0579 0.0497 0.0497
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.1062 0.095 0.095
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0092 0.0041 0.0041
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0579 0.0497 0.0497
Brugia malayi Protein kinase domain containing protein 0.0748 0.0655 0.0921
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.1912 0.1747 0.5833
Brugia malayi Immunoglobulin I-set domain containing protein 0.0155 0.01 0.0139
Entamoeba histolytica protein kinase, putative 0.0082 0.0032 0.0045
Loa Loa (eye worm) cyclin domain-containing protein 0.0679 0.0591 0.066
Trichomonas vaginalis PIKK family atypical protein kinase 0.1898 0.1734 0.2426
Schistosoma mansoni cyclin B3 0.0679 0.0591 0.0589
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0075 0.0025 0.0025
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0112 0.006 0.006
Onchocerca volvulus Peroxidasin homolog 0.0075 0.0025 0.0251
Schistosoma mansoni ephrin receptor 0.0117 0.0064 0.0062
Echinococcus multilocularis serine protein kinase ATM 0.1604 0.1458 0.1458
Loa Loa (eye worm) phosphatidylinositol 3 0.0579 0.0497 0.0556
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.008 0.0029 0.0028
Schistosoma mansoni hypothetical protein 0.0075 0.0025 0.0024
Schistosoma mansoni factor for adipocyte differentiation 0.008 0.0029 0.0028
Brugia malayi Fibronectin type III domain containing protein 0.008 0.0029 0.0039
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0179 0.0122 0.0135
Echinococcus granulosus Fibronectin type III domain containing protein 0.008 0.0029 0.0029
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0157 0.0102 0.0102
Echinococcus multilocularis lachesin 0.0083 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0075 0.0025 0.0024
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.0131 0.0077 0.0385
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.1604 0.1458 0.2053
Echinococcus multilocularis cyclin dependent kinase 0.065 0.0564 0.0564
Trichomonas vaginalis AGC family protein kinase 0.0092 0.0041 0.0037
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0579 0.0497 0.0497
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.1176 0.1057 0.1057
Toxoplasma gondii cyclin 4, putative 0.0131 0.0077 0.0385
Loa Loa (eye worm) hypothetical protein 0.0075 0.0025 0.0027
Schistosoma mansoni cyclins 0.0543 0.0463 0.0462
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0092 0.0041 0.0041
Echinococcus multilocularis cyclin t1 0.0131 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0075 0.0025 0.0027
Brugia malayi Immunoglobulin I-set domain containing protein 0.0162 0.0107 0.0149
Echinococcus multilocularis 0.0075 0.0025 0.0025
Echinococcus multilocularis tyrosine protein kinase ABL1 0.005 0.0001 0.0001
Entamoeba histolytica cell division protein kinase 2, putative 0.065 0.0564 0.0795
Echinococcus multilocularis epidermal growth factor receptor 0.0289 0.0225 0.0225
Onchocerca volvulus 0.0075 0.0025 0.0251
Echinococcus granulosus anosmin 1 0.008 0.0029 0.0029
Echinococcus granulosus cyclin dependent kinase 0.065 0.0564 0.0564
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.4717 0.4375 1
Echinococcus granulosus tyrosine protein kinase Src64B 0.0092 0.0041 0.0041
Brugia malayi Fibronectin type III domain containing protein 0.008 0.0029 0.0039
Schistosoma mansoni tyrosine kinase 0.012 0.0067 0.0065
Echinococcus multilocularis cyclins 0.0543 0.0463 0.0463
Loa Loa (eye worm) hypothetical protein 0.0162 0.0107 0.0118
Onchocerca volvulus 0.0155 0.01 0.1039
Trichomonas vaginalis PIKK family atypical protein kinase 0.1887 0.1723 0.2412
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.008 0.0029 0.0039
Echinococcus granulosus tyrosine protein kinase Fyn 0.0092 0.0041 0.0041
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.7625 0.71 1
Echinococcus multilocularis rac serine:threonine kinase 0.0051 0.0002 0.0002
Echinococcus multilocularis cyclins 0.0543 0.0463 0.0463
Onchocerca volvulus 0.0131 0.0077 0.0802
Brugia malayi Cyclin, N-terminal domain containing protein 0.0131 0.0077 0.0107
Echinococcus multilocularis fibronectin type III domain-containing protein 0.008 0.0029 0.0029
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0083 0.0032 0.0034
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.1008 0.0899 0.1266
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0075 0.0025 0.0027
Loa Loa (eye worm) hypothetical protein 0.0083 0.0032 0.0034
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.1499 0.1359 0.7826
Entamoeba histolytica protein kinase domain containing protein 0.1062 0.095 0.1337
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.1499 0.1359 0.1913
Loa Loa (eye worm) hypothetical protein 0.0314 0.0249 0.0277
Onchocerca volvulus 0.0075 0.0025 0.0251
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0579 0.0497 0.0682
Entamoeba histolytica hypothetical protein 0.0131 0.0077 0.0109
Leishmania major phosphatidylinositol kinase related protein, putative 0.1008 0.0899 0.2984
Echinococcus multilocularis insulin growth factor binding 0.0075 0.0025 0.0025
Loa Loa (eye worm) TK/EGFR protein kinase 0.0289 0.0225 0.0251
Loa Loa (eye worm) one IG domain family member 0.0075 0.0025 0.0027
Schistosoma mansoni titin 0.0155 0.01 0.0099
Brugia malayi protein-tyrosine kinase 0.0085 0.0035 0.0047
Leishmania major cyclin 9, putative 0.0131 0.0077 0.0223
Echinococcus granulosus CDC7 cell division cycle 7 0.0092 0.0041 0.0041
Echinococcus granulosus titin 0.0075 0.0025 0.0025
Giardia lamblia Kinase, CMGC CDK 0.065 0.0564 0.1289
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.4407 0.4085 0.4085
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.008 0.0029 0.0029
Echinococcus multilocularis protein kinase shaggy 0.1062 0.095 0.095
Giardia lamblia Cyclin fold protein 1, putative 0.0131 0.0077 0.0177
Echinococcus granulosus roundabout 2 0.0218 0.0159 0.0159
Schistosoma mansoni septate junction protein 0.0083 0.0032 0.0031
Echinococcus multilocularis cyclin B3 1 0.0543 0.0463 0.0463
Schistosoma mansoni cyclin k 0.0131 0.0077 0.0076
Toxoplasma gondii non-specific serine/threonine protein kinase 0.1279 0.1153 0.6632
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.1062 0.095 0.3154
Entamoeba histolytica hypothetical protein 0.6477 0.6024 0.8485
Trichomonas vaginalis conserved hypothetical protein 0.0543 0.0463 0.0634
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.006 0.0011 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.1887 0.1723 0.2412
Leishmania major mitotic cyclin, putative 0.0131 0.0077 0.0223
Schistosoma mansoni hypothetical protein 0.008 0.0029 0.0028
Trypanosoma cruzi mitotic cyclin, putative 0.0131 0.0077 0.0109
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.1912 0.1747 0.5833
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0114 0.0061 0.0084
Loa Loa (eye worm) cyclin domain-containing protein 0.0131 0.0077 0.0085
Trichomonas vaginalis STE family protein kinase 0.0114 0.0061 0.0066
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.3347 0.3091 0.4354
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0092 0.0041 0.0057
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0131 0.0077 0.0077
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1176 0.1057 0.1487
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.1912 0.1747 0.7161
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.1499 0.1359 0.1898
Echinococcus multilocularis aurora kinase A 0.0092 0.0041 0.0041
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.1912 0.1747 0.1747
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0082 0.0032 0.0034
Entamoeba histolytica SH2-protein kinase domain containing protein 0.005 0.0001 0.0002
Schistosoma mansoni cell adhesion molecule 0.0083 0.0032 0.0031
Onchocerca volvulus 0.0579 0.0497 0.5232
Brugia malayi Immunoglobulin I-set domain containing protein 0.0162 0.0107 0.0149
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.065 0.0564 0.1859
Schistosoma mansoni cyclin G2 0.0131 0.0077 0.0076
Echinococcus multilocularis raf serine:threonine protein kinase 0.03 0.0236 0.0236
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0092 0.0041 0.0298
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.1912 0.1747 0.246
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.008 0.0029 0.0031
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.1499 0.1359 0.1914
Schistosoma mansoni cell adhesion molecule 0.0143 0.0088 0.0087
Echinococcus granulosus tyrosine kinase 0.0085 0.0035 0.0035
Schistosoma mansoni tyrosine kinase 0.0168 0.0112 0.0111
Echinococcus granulosus tyrosine protein kinase Fyn 0.0092 0.0041 0.0041
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.1499 0.1359 0.1522
Loa Loa (eye worm) phosphatidylinositol 3 0.0579 0.0497 0.0556
Echinococcus multilocularis Cyclin L1 0.0131 0.0077 0.0077
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0679 0.0591 0.0591
Entamoeba histolytica protein kinase rad3, putative 0.1176 0.1057 0.1488
Echinococcus multilocularis 0.0077 0.0027 0.0027
Echinococcus granulosus epidermal growth factor receptor 0.0289 0.0225 0.0225
Trichomonas vaginalis AGC family protein kinase 0.0092 0.0041 0.0037
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.4407 0.4085 0.5752
Echinococcus granulosus neuroglian 0.0131 0.0077 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.1898 0.1734 0.2426
Trichomonas vaginalis PIKK family atypical protein kinase 0.1887 0.1723 0.2411
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0579 0.0497 0.0496
Loa Loa (eye worm) TK protein kinase 0.0072 0.0022 0.0024
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0131 0.0077 0.0077
Echinococcus multilocularis cyclin dependent kinase 5 0.065 0.0564 0.0564
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0025 0.0034
Giardia lamblia Kinase, CMGC MAPK 0.0085 0.0034 0.0078
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.008 0.0029 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.1198 0.1078 0.15
Echinococcus multilocularis cyclin dependent kinase 1 0.065 0.0564 0.0564
Brugia malayi Immunoglobulin I-set domain containing protein 0.0083 0.0032 0.0043
Echinococcus multilocularis anosmin 1 0.008 0.0029 0.0029
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0131 0.0077 0.0076
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.1062 0.095 0.1337
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0075 0.0025 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.1898 0.1734 0.2426
Loa Loa (eye worm) hypothetical protein 0.0314 0.0249 0.0277
Trichomonas vaginalis PIKK family atypical protein kinase 0.1198 0.1078 0.15
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.1499 0.1359 0.1914
Echinococcus granulosus glycogen synthase kinase 3 beta 0.1062 0.095 0.095
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0579 0.0497 0.0496
Trichomonas vaginalis PIKK family atypical protein kinase 0.1898 0.1734 0.2426
Echinococcus multilocularis usherin 0.008 0.0029 0.0029
Entamoeba histolytica protein kinase, putative 0.0064 0.0014 0.002
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0679 0.0591 0.0591
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.2647 0.2435 0.3429
Brugia malayi Myb-like DNA-binding domain containing protein 0.0075 0.0025 0.0034
Loa Loa (eye worm) phosphatidylinositol kinase 0.0579 0.0497 0.0556
Schistosoma mansoni cell adhesion molecule 0.0155 0.01 0.0099
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0041 0.0038
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.005 0.0001 0.0001
Brugia malayi Fibronectin type III domain containing protein 0.008 0.0029 0.0039
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.219 0.2007 0.8234
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0063 0.0014 0.0014
Trichomonas vaginalis cyclin B, putative 0.0604 0.052 0.0714
Echinococcus multilocularis mitogen activated protein kinase 0.0085 0.0034 0.0034
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.008 0.0029 0.0028
Entamoeba histolytica cyclin C, putative 0.0131 0.0077 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.1912 0.1747 0.2445
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0087 0.0036 0.0036
Trichomonas vaginalis cyclin B, putative 0.0604 0.052 0.0714
Giardia lamblia Hypothetical protein 0.0579 0.0497 0.1137
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0114 0.0061 0.0168
Brugia malayi myotactin form B 0.008 0.0029 0.0039
Loa Loa (eye worm) AGC/AKT protein kinase 0.0064 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.008 0.0029 0.0031
Loa Loa (eye worm) phosphatidylinositol 3 0.9571 0.8924 1
Echinococcus granulosus EG95 0.008 0.0029 0.0029
Brugia malayi Raf kinase 0.0291 0.0227 0.0318
Trichomonas vaginalis AGC family protein kinase 0.0092 0.0041 0.0037
Schistosoma mansoni titin 0.008 0.0029 0.0028
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0162 0.0107 0.0107
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.008 0.0029 0.0031
Echinococcus multilocularis epidermal growth factor receptor 0.0205 0.0147 0.0147
Echinococcus granulosus anosmin 1 0.008 0.0029 0.0029
Brugia malayi Protein-tyrosine phosphatase 0.008 0.0029 0.0039
Toxoplasma gondii hypothetical protein 0.0131 0.0077 0.0385
Loa Loa (eye worm) cyclin C 0.0131 0.0077 0.0085
Plasmodium falciparum glycogen synthase kinase 3 0.1062 0.095 0.6987
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0075 0.0025 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.2656 0.2444 0.3442
Trichomonas vaginalis PIKK family atypical protein kinase 0.1912 0.1747 0.2445
Trypanosoma cruzi mitotic cyclin, putative 0.0131 0.0077 0.0109
Entamoeba histolytica hypothetical protein 0.0579 0.0497 0.0701
Brugia malayi Immunoglobulin I-set domain containing protein 0.0083 0.0032 0.0043
Schistosoma mansoni hypothetical protein 0.0131 0.0077 0.0076
Brugia malayi phosphoinositide-dependent protein kinase I 0.0082 0.0032 0.0043
Entamoeba histolytica protein kinase, putative 0.1062 0.095 0.1337
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0085 0.0034 0.0078
Plasmodium vivax cyclin dependent kinase binding protein, putative 0.0131 0.0077 0.0569
Echinococcus granulosus cyclin G2 0.0131 0.0077 0.0077
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0155 0.01 0.011
Brugia malayi hypothetical protein 0.0131 0.0077 0.0107
Schistosoma mansoni serine/threonine protein kinase 0.0179 0.0122 0.0121
Onchocerca volvulus 0.0155 0.01 0.1039
Echinococcus multilocularis titin 0.0075 0.0025 0.0025
Brugia malayi Prion-like- 0.0083 0.0032 0.0043
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.1499 0.1359 0.1359
Schistosoma mansoni cell adhesion molecule 0.0162 0.0107 0.0105
Loa Loa (eye worm) hypothetical protein 0.008 0.0029 0.0031
Schistosoma mansoni titin 0.0075 0.0025 0.0024
Loa Loa (eye worm) TK protein kinase 0.0232 0.0172 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.1876 0.1713 0.2397
Trypanosoma cruzi aurora B kinase, putative 0.0092 0.0041 0.0057
Echinococcus multilocularis cyclins 0.0543 0.0463 0.0463
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0047 0.0046
Trichomonas vaginalis STE family protein kinase 0.0114 0.0061 0.0066
Loa Loa (eye worm) CDC7 protein kinase 0.0092 0.0041 0.0045
Schistosoma mansoni protein kinase 0.006 0.0011 0.001
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0579 0.0497 0.0496
Trypanosoma brucei mitotic cyclin 0.0131 0.0077 0.0273
Loa Loa (eye worm) hypothetical protein 0.0604 0.052 0.0582
Loa Loa (eye worm) AUR protein kinase 0.0092 0.0041 0.0044
Onchocerca volvulus 0.008 0.0029 0.0295
Echinococcus granulosus cyclin b3 0.0543 0.0463 0.0463
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0579 0.0497 0.0699
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0748 0.0655 0.0733
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0155 0.01 0.011
Echinococcus multilocularis Netrin receptor DCC 0.008 0.0029 0.0029
Loa Loa (eye worm) cyclin domain-containing protein 0.0131 0.0077 0.0085
Entamoeba histolytica protein kinase, putative 0.0061 0.0012 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0034 0.0033
Loa Loa (eye worm) hypothetical protein 0.0075 0.0025 0.0027
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0092 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.07 0.0611 0.0609
Loa Loa (eye worm) hypothetical protein 0.008 0.0029 0.0031
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.3347 0.3091 0.3091
Toxoplasma gondii target of rapamycin (TOR), putative 0.1898 0.1734 1
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.1499 0.1359 0.1359
Trypanosoma brucei cdc2-related kinase 1 0.065 0.0564 0.2282
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.1499 0.1359 1
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0112 0.006 0.006
Trichomonas vaginalis cyclin A, putative 0.0604 0.052 0.0714
Trichomonas vaginalis PIKK family atypical protein kinase 0.1887 0.1723 0.2412
Entamoeba histolytica protein kinase, putative 0.0092 0.0041 0.0057
Trichomonas vaginalis cyclin B3, putative 0.0543 0.0463 0.0634
Echinococcus granulosus cyclins 0.0543 0.0463 0.0463
Trichomonas vaginalis PIKK family atypical protein kinase 0.1201 0.108 0.1504
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0082 0.0032 0.0032
Echinococcus multilocularis activin receptor type 0.006 0.0011 0.0011
Echinococcus granulosus defective proboscis extension response 0.0056 0.0007 0.0007
Brugia malayi Immunoglobulin I-set domain containing protein 0.0155 0.01 0.0139
Brugia malayi Immunoglobulin I-set domain containing protein 0.0075 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.008 0.0029 0.0031
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.065 0.0564 0.0631
Loa Loa (eye worm) hypothetical protein 0.3218 0.297 0.3327
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.3094 0.2854 0.4019
Trichomonas vaginalis CMGC family protein kinase 0.065 0.0564 0.0776
Trichomonas vaginalis PIKK family atypical protein kinase 0.1901 0.1736 0.243
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0579 0.0497 0.0497
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0579 0.0497 0.0701
Echinococcus granulosus fibronectin type III domain-containing protein 0.008 0.0029 0.0029
Echinococcus multilocularis cyclin G2 0.0131 0.0077 0.0077
Brugia malayi Fibronectin type III domain containing protein 0.008 0.0029 0.0039
Schistosoma mansoni Cyclin fold protein 0.0131 0.0077 0.0076
Echinococcus granulosus tyrosine protein kinase Srms 0.005 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.1887 0.1723 0.2412
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.1499 0.1359 0.1898
Brugia malayi Immunoglobulin I-set domain containing protein 0.0083 0.0032 0.0043
Echinococcus granulosus cyclin 0.0131 0.0077 0.0077
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0748 0.0655 0.0655
Trichomonas vaginalis PIKK family atypical protein kinase 0.1901 0.1736 0.243
Schistosoma mansoni serine/threonine-protein kinase 0.0051 0.0002 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0155 0.01 0.0139
Schistosoma mansoni protein kinase 0.0114 0.0061 0.006
Echinococcus multilocularis CDC7 cell division cycle 7 0.0092 0.0041 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0082 0.0032 0.0025
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.7625 0.71 1
Schistosoma mansoni vesicular amine transporter 0.0057 0.0008 0.0007
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0075 0.0025 0.0024
Echinococcus granulosus cyclins 0.0543 0.0463 0.0463
Loa Loa (eye worm) CYL-1 protein 0.0131 0.0077 0.0085
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0579 0.0497 0.0682
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.065 0.0564 0.3211
Entamoeba histolytica cyclin, putative 0.0604 0.052 0.0733
Trypanosoma cruzi cdc2-related kinase 3 0.065 0.0564 0.0795
Echinococcus granulosus c src tyrosine kinase 0.0057 0.0008 0.0008
Echinococcus granulosus mitogen activated protein kinase 0.0085 0.0034 0.0034
Trypanosoma brucei Fibronectin type III domain containing protein, putative 0.008 0.0029 0.0075
Loa Loa (eye worm) hypothetical protein 0.0083 0.0032 0.0034
Schistosoma mansoni tyrosine kinase 0.0168 0.0112 0.0111
Loa Loa (eye worm) hypothetical protein 0.008 0.0029 0.0031
Echinococcus granulosus roundabout 2 0.0162 0.0107 0.0107
Echinococcus granulosus peroxidasin 0.0083 0.0032 0.0032
Echinococcus multilocularis cyclin B 0.0604 0.052 0.052
Schistosoma mansoni tyrosine kinase 0.0092 0.0041 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0077 0.0089
Loa Loa (eye worm) phosphatidylinositol 3 0.1912 0.1747 0.1956
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.008 0.0029 0.0029
Onchocerca volvulus 0.008 0.0029 0.0295
Leishmania major hypothetical protein, conserved 0.3235 0.2987 1
Trypanosoma cruzi cdc2-related kinase 1 0.065 0.0564 0.0795
Loa Loa (eye worm) phosphatidylinositol 3 0.0579 0.0497 0.0556
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0032 0.003
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0748 0.0655 0.0921
Loa Loa (eye worm) hypothetical protein 0.0075 0.0025 0.0027
Echinococcus multilocularis G1:S specific cyclin D1 0.0131 0.0077 0.0077
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1062 0.095 0.1063
Trypanosoma cruzi hypothetical protein, conserved 0.0131 0.0077 0.0109
Loa Loa (eye worm) hypothetical protein 0.1176 0.1057 0.1183
Giardia lamblia Cyclin B-like protein 0.0131 0.0077 0.0177
Trichomonas vaginalis cyclins, putative 0.0192 0.0134 0.0169
Trypanosoma brucei aurora B kinase 0.0092 0.0041 0.0122
Entamoeba histolytica cyclin, domain containing protein 0.0131 0.0077 0.0109
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.3347 0.3091 0.3091
Trichomonas vaginalis CMGC family protein kinase 0.1062 0.095 0.132

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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